2JC5A

Apurinic apyrimidinic (ap) endonuclease (nape) from neisseria meningitidis
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Ap Endonuclease Paralogues with Distinct Activities in DNA Repair and Bacterial Pathogenesis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Neisseria meningitidis
molecule keywords EXODEOXYRIBONUCLEASE
total genus 83
structure length 259
sequence length 259
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2006-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 2jc5A00
3NGQA 5INQA 5INLA 1HD7A 3G0AA 4L1YA 5DV4A 1YJHA 5DFIA 2O3CA 4GZ2A 4QHEA 4LNDA 1ZWXA 5A7IA 2DDTA 1DNKA 2A42B 1Y21A 5J3PA 4B5GA 2J63A 4CMLA 3NGOA 5EWTA 2JC5A 4FPVA 3I5VA 2F1NA 3WCXA 5INNA 5DFHA 3G91A 4F1HA 3G1KA 5DG0A 4B5FA 2D1KB 3FZIA 2DNJA 2F2FB 4F1IA 1DE8A 3MTCA 1WDUA 4QHDA 4GZ1A 4IEMA 3I41A 2O3HA 5J3ZA 5A7JA 3G3CA 1DEWA 5DFJA 2XSWA 1SR4B 2A3ZB 1BIXA 1DE9A 5J42A 4L1ZA 2IMQX 5INOA 5CFGA 4F1RA 2ISIA 5DV2A 3W2XA 4GZ0A 5DFFA 2V0RA 1SI6X 4B5IA 5HT2A 3G6SA 1VYBA 3CJCD 1NTFA 2JC4A 3G0RA 1AKOA 3MPRA 4L21A 5INPA 3G8VA 4FVAA 4L20A 3I48A 5J8NA 4RUWA 4PUQA 2DDSA 4K6LF 2VOAA 2A41B 2UYRX 2DDRA 4AWNA 5INKA 3G2CA 1ATND 2EI9A 3NGNA 3L1WA 3G38A 3NR8A 4QH9A 2V0SA 4B5JA 4C1RA 1E9NA 3K55A 3G00A 3DNIA 3TEBA 3G3YA 4B5HA 3U8UA 1I9YA 3G2DA 3I46A 2A40B 3N9VA 4GYZA 3W2YA 4F1HB 3W3DB 4A9CA 1I9ZA 5CFEA 3GA6A 3G4TA 4JG3A 4CMNA 4B5MA 4GEWA 5J3SA 5INMA
chains in the Genus database with same CATH superfamily
3NGQA 5INQA 5INLA 1HD7A 3G0AA 4L1YA 5DV4A 1YJHA 5DFIA 2O3CA 4GZ2A 4QHEA 4LNDA 1ZWXA 5A7IA 2DDTA 1DNKA 2A42B 1Y21A 5J3PA 4B5GA 2J63A 4CMLA 3NGOA 5EWTA 2JC5A 4FPVA 3I5VA 2F1NA 3WCXA 5INNA 5DFHA 3G91A 4F1HA 3G1KA 5DG0A 4B5FA 2D1KB 3FZIA 2DNJA 2F2FB 4F1IA 1DE8A 3MTCA 1WDUA 4QHDA 4GZ1A 4IEMA 3I41A 2O3HA 5J3ZA 5A7JA 3G3CA 1DEWA 5DFJA 2XSWA 1SR4B 2A3ZB 1BIXA 1DE9A 5J42A 4L1ZA 2IMQX 5INOA 5CFGA 4F1RA 2ISIA 5DV2A 3W2XA 4GZ0A 5DFFA 2V0RA 1SI6X 4B5IA 5HT2A 3G6SA 1VYBA 3CJCD 1NTFA 2JC4A 3G0RA 1AKOA 3MPRA 4L21A 5INPA 3G8VA 4FVAA 4L20A 3I48A 5J8NA 4RUWA 4PUQA 2DDSA 4K6LF 2VOAA 2A41B 2UYRX 2DDRA 4AWNA 5INKA 3G2CA 1ATND 2EI9A 3NGNA 3L1WA 3G38A 3NR8A 4QH9A 2V0SA 4B5JA 4C1RA 1E9NA 3K55A 3G00A 3DNIA 3TEBA 3G3YA 4B5HA 3U8UA 1I9YA 3G2DA 3I46A 2A40B 3N9VA 4GYZA 3W2YA 4F1HB 3W3DB 4A9CA 1I9ZA 5CFEA 3GA6A 3G4TA 4JG3A 4CMNA 4B5MA 4GEWA 5J3SA 5INMA
chains in the Genus database with same CATH topology
3NGQA 5INQA 5INLA 1HD7A 3G0AA 4L1YA 5DV4A 1YJHA 5DFIA 2O3CA 4GZ2A 4QHEA 4LNDA 1ZWXA 5A7IA 2DDTA 1DNKA 2A42B 1Y21A 5J3PA 4B5GA 2J63A 4CMLA 3NGOA 5EWTA 2JC5A 4FPVA 3I5VA 2F1NA 3WCXA 5INNA 5DFHA 3G91A 4F1HA 3G1KA 5DG0A 4B5FA 2D1KB 3FZIA 2DNJA 2F2FB 4F1IA 1DE8A 3MTCA 1WDUA 4QHDA 4GZ1A 4IEMA 3I41A 2O3HA 5J3ZA 5A7JA 3G3CA 1DEWA 5DFJA 2XSWA 1SR4B 2A3ZB 1BIXA 1DE9A 5J42A 4L1ZA 2IMQX 5INOA 5CFGA 4F1RA 2ISIA 5DV2A 3W2XA 4GZ0A 5DFFA 2V0RA 1SI6X 4B5IA 5HT2A 3G6SA 1VYBA 3CJCD 1NTFA 2JC4A 3G0RA 1AKOA 3MPRA 4L21A 5INPA 3G8VA 4FVAA 4L20A 3I48A 5J8NA 4RUWA 4PUQA 2DDSA 4K6LF 2VOAA 2A41B 2UYRX 2DDRA 4AWNA 5INKA 3G2CA 1ATND 2EI9A 3NGNA 3L1WA 3G38A 3NR8A 4QH9A 2V0SA 4B5JA 4C1RA 1E9NA 3K55A 3G00A 3DNIA 3TEBA 3G3YA 4B5HA 3U8UA 1I9YA 3G2DA 3I46A 2A40B 3N9VA 4GYZA 3W2YA 4F1HB 3W3DB 4A9CA 1I9ZA 5CFEA 3GA6A 3G4TA 4JG3A 4CMNA 4B5MA 4GEWA 5J3SA 5INMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NGQ A;  5INQ A;  5INL A;  1HD7 A;  3G0A A;  4L1Y A;  5DV4 A;  1YJH A;  5DFI A;  2O3C A;  4GZ2 A;  4QHE A;  4LND A;  1ZWX A;  5A7I A;  2DDT A;  1DNK A;  2A42 B;  1Y21 A;  5J3P A;  4B5G A;  2J63 A;  4CML A;  3NGO A;  5EWT A;  2JC5 A;  4FPV A;  3I5V A;  2F1N A;  3WCX A;  5INN A;  5DFH A;  3G91 A;  4F1H A;  3G1K A;  5DG0 A;  4B5F A;  2D1K B;  3FZI A;  2DNJ A;  2F2F B;  4F1I A;  1DE8 A;  3MTC A;  1WDU A;  4QHD A;  4GZ1 A;  4IEM A;  3I41 A;  2O3H A;  5J3Z A;  5A7J A;  3G3C A;  1DEW A;  5DFJ A;  2XSW A;  1SR4 B;  2A3Z B;  1BIX A;  1DE9 A;  5J42 A;  4L1Z A;  2IMQ X;  5INO A;  5CFG A;  4F1R A;  2ISI A;  5DV2 A;  3W2X A;  4GZ0 A;  5DFF A;  2V0R A;  1SI6 X;  4B5I A;  5HT2 A;  3G6S A;  1VYB A;  3CJC D;  1NTF A;  2JC4 A;  3G0R A;  1AKO A;  3MPR A;  4L21 A;  5INP A;  3G8V A;  4FVA A;  4L20 A;  3I48 A;  5J8N A;  4RUW A;  4PUQ A;  2DDS A;  4K6L F;  2VOA A;  2A41 B;  2UYR X;  2DDR A;  4AWN A;  5INK A;  3G2C A;  1ATN D;  2EI9 A;  3NGN A;  3L1W A;  3G38 A;  3NR8 A;  4QH9 A;  2V0S A;  4B5J A;  4C1R A;  1E9N A;  3K55 A;  3G00 A;  3DNI A;  3TEB A;  3G3Y A;  4B5H A;  3U8U A;  1I9Y A;  3G2D A;  3I46 A;  2A40 B;  3N9V A;  4GYZ A;  3W2Y A;  4F1H B;  3W3D B;  4A9C A;  1I9Z A;  5CFE A;  3GA6 A;  3G4T A;  4JG3 A;  4CMN A;  4B5M A;  4GEW A;  5J3S A;  5INM A; 
#chains in the Genus database with same CATH topology
 3NGQ A;  5INQ A;  5INL A;  1HD7 A;  3G0A A;  4L1Y A;  5DV4 A;  1YJH A;  5DFI A;  2O3C A;  4GZ2 A;  4QHE A;  4LND A;  1ZWX A;  5A7I A;  2DDT A;  1DNK A;  2A42 B;  1Y21 A;  5J3P A;  4B5G A;  2J63 A;  4CML A;  3NGO A;  5EWT A;  2JC5 A;  4FPV A;  3I5V A;  2F1N A;  3WCX A;  5INN A;  5DFH A;  3G91 A;  4F1H A;  3G1K A;  5DG0 A;  4B5F A;  2D1K B;  3FZI A;  2DNJ A;  2F2F B;  4F1I A;  1DE8 A;  3MTC A;  1WDU A;  4QHD A;  4GZ1 A;  4IEM A;  3I41 A;  2O3H A;  5J3Z A;  5A7J A;  3G3C A;  1DEW A;  5DFJ A;  2XSW A;  1SR4 B;  2A3Z B;  1BIX A;  1DE9 A;  5J42 A;  4L1Z A;  2IMQ X;  5INO A;  5CFG A;  4F1R A;  2ISI A;  5DV2 A;  3W2X A;  4GZ0 A;  5DFF A;  2V0R A;  1SI6 X;  4B5I A;  5HT2 A;  3G6S A;  1VYB A;  3CJC D;  1NTF A;  2JC4 A;  3G0R A;  1AKO A;  3MPR A;  4L21 A;  5INP A;  3G8V A;  4FVA A;  4L20 A;  3I48 A;  5J8N A;  4RUW A;  4PUQ A;  2DDS A;  4K6L F;  2VOA A;  2A41 B;  2UYR X;  2DDR A;  4AWN A;  5INK A;  3G2C A;  1ATN D;  2EI9 A;  3NGN A;  3L1W A;  3G38 A;  3NR8 A;  4QH9 A;  2V0S A;  4B5J A;  4C1R A;  1E9N A;  3K55 A;  3G00 A;  3DNI A;  3TEB A;  3G3Y A;  4B5H A;  3U8U A;  1I9Y A;  3G2D A;  3I46 A;  2A40 B;  3N9V A;  4GYZ A;  3W2Y A;  4F1H B;  3W3D B;  4A9C A;  1I9Z A;  5CFE A;  3GA6 A;  3G4T A;  4JG3 A;  4CMN A;  4B5M A;  4GEW A;  5J3S A;  5INM A; 
#chains in the Genus database with same CATH homology
 3NGQ A;  5INQ A;  5INL A;  1HD7 A;  3G0A A;  4L1Y A;  5DV4 A;  1YJH A;  5DFI A;  2O3C A;  4GZ2 A;  4QHE A;  4LND A;  1ZWX A;  5A7I A;  2DDT A;  1DNK A;  2A42 B;  1Y21 A;  5J3P A;  4B5G A;  2J63 A;  4CML A;  3NGO A;  5EWT A;  2JC5 A;  4FPV A;  3I5V A;  2F1N A;  3WCX A;  5INN A;  5DFH A;  3G91 A;  4F1H A;  3G1K A;  5DG0 A;  4B5F A;  2D1K B;  3FZI A;  2DNJ A;  2F2F B;  4F1I A;  1DE8 A;  3MTC A;  1WDU A;  4QHD A;  4GZ1 A;  4IEM A;  3I41 A;  2O3H A;  5J3Z A;  5A7J A;  3G3C A;  1DEW A;  5DFJ A;  2XSW A;  1SR4 B;  2A3Z B;  1BIX A;  1DE9 A;  5J42 A;  4L1Z A;  2IMQ X;  5INO A;  5CFG A;  4F1R A;  2ISI A;  5DV2 A;  3W2X A;  4GZ0 A;  5DFF A;  2V0R A;  1SI6 X;  4B5I A;  5HT2 A;  3G6S A;  1VYB A;  3CJC D;  1NTF A;  2JC4 A;  3G0R A;  1AKO A;  3MPR A;  4L21 A;  5INP A;  3G8V A;  4FVA A;  4L20 A;  3I48 A;  5J8N A;  4RUW A;  4PUQ A;  2DDS A;  4K6L F;  2VOA A;  2A41 B;  2UYR X;  2DDR A;  4AWN A;  5INK A;  3G2C A;  1ATN D;  2EI9 A;  3NGN A;  3L1W A;  3G38 A;  3NR8 A;  4QH9 A;  2V0S A;  4B5J A;  4C1R A;  1E9N A;  3K55 A;  3G00 A;  3DNI A;  3TEB A;  3G3Y A;  4B5H A;  3U8U A;  1I9Y A;  3G2D A;  3I46 A;  2A40 B;  3N9V A;  4GYZ A;  3W2Y A;  4F1H B;  3W3D B;  4A9C A;  1I9Z A;  5CFE A;  3GA6 A;  3G4T A;  4JG3 A;  4CMN A;  4B5M A;  4GEW A;  5J3S A;  5INM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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