3R5PA

Structure of ddn, the deazaflavin-dependent nitroreductase from mycobacterium tuberculosis involved in bioreductive activation of pa-824
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
113
structure length
113
Chain Sequence
GTFQKIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Deazaflavin-dependent nitroreductase
total genus 25
structure length 113
sequence length 113
ec nomenclature ec 1.-.-.-:
pdb deposition date 2011-03-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.110.10 Mainly Beta Roll Pnp Oxidase; Chain A Electron Transport, Fmn-binding Protein; Chain A 3r5pA00
2OU5A 3U35A 3AWHA 3ZOCA 2PTFA 1WLIA 3FKHA 4ZKYA 2E83A 2D36A 3TGVA 1G78A 1NRGA 2ASFA 3VYAA 3GASA 4HMSA 1XHNA 4YBNA 1I0RA 1T9MA 2IMLA 1Y30A 2D38A 1WGBA 3BA3A 3BNKA 2ECRA 2FG9A 1W3OA 1W3QA 3ZODA 3HMZA 2FURA 4F07A 2HQ7A 3A6QA 3KYGA 4HMUA 3RH7A 3B5MA 1DNLA 2X1KA 4HMTA 2ECUA 2R0XA 2ARZA 1WLKA 1USCA 4Y9IA 1W9AA 1WV4A 4Z85A 5ESCA 2GJGA 3BPKA 3E4VA 3U5WA 3K86A 2D37A 4R82A 2QCKA 3H96A 3ZOFA 3DB0A 5JABA 3AMFA 1RZ0A 4HMVA 3ZOEA 1RFEA 3CP3A 1AXJA 3K87A 3R5PA 1FLMA 2I51A 3FGEA 2ED4A 3VY2A 3A6RA 3DNHA 1G77A 1RZ1A 1JNWA 3A20A 2FHQA 3F7EA 5CHOA 2HHZA 1I0SA 1W3PA 3K88A 2R6VA 4XJ2A 2D5MA 3R5WA 2X1JA 1CI0A 4N7RC 3U34A 2RDEA 4L82A 2HQ9A 2IABA 1YOAA 2HTIA 2I02A 5CHEC 1G79A 3ZOHA 3CB0A 2Q9KA 2AQ6A 3EC6A 4XHYA 2IG6A 2NR4A 1W3RA 4IRAA 3SWJA 4HX6A 3R5YA 2OL5A 1VL7A 3R5ZA 2A2JA 3R5LA 4HMXA 4YWNA 1USFA 3DMBA 1G76A 3R5RA 4HMWA 5BNCA 2VPAA 1YLNA 3VY5A 3PFTA 3ZOGA 3KYFA 3U0IA 1XXOA 1TY9A 3IN6A 2RE7A 3NFWA 3HY8A 2HTDA 4QVBA 2QEAA 1EJEA
chains in the Genus database with same CATH superfamily
3V4HA 2OU5A 3U35A 3AWHA 3ZOCA 2PTFA 1WLIA 3FKHA 4ZKYA 2E83A 2P5ZX 2D36A 3TGVA 1G78A 1NRGA 2ASFA 3VYAA 3GASA 4HMSA 1XHNA 4YBNA 1I0RA 1T9MA 2IMLA 4W64A 1Y30A 2D38A 1WGBA 3BA3A 3BNKA 2ECRA 2FG9A 1W3OA 1W3QA 3ZODA 3HMZA 2FURA 4F07A 2HQ7A 3A6QA 3KYGA 4HMUA 3RH7A 3B5MA 1DNLA 2X1KA 4HMTA 2ECUA 2R0XA 2ARZA 1WLKA 1USCA 4Y9IA 1W9AA 1WV4A 4TV4A 4Z85A 5ESCA 2GJGA 3BPKA 3E4VA 3U5WA 4HKHA 3K86A 2D37A 4UHVA 4R82A 2QCKA 3H96A 3ZOFA 3DB0A 5JABA 3AMFA 1RZ0A 4HMVA 3ZOEA 3HE1A 1RFEA 3CP3A 1AXJA 3K87A 3R5PA 1FLMA 2I51A 3FGEA 2ED4A 3VY2A 3A6RA 3DNHA 1G77A 1RZ1A 2GUJA 3EAAA 1JNWA 3A20A 2FHQA 3F7EA 5CHOA 2HHZA 1I0SA 1W3PA 3K88A 2R6VA 4XJ2A 2D5MA 3R5WA 2X1JA 1CI0A 4N7RC 3U34A 2RDEA 4L82A 2HQ9A 2IABA 1YOAA 2HTIA 2I02A 5CHEC 1G79A 3ZOHA 3CB0A 2K4QA 2Q9KA 2AQ6A 1Y12A 3EC6A 4XHYA 2IG6A 2NR4A 1W3RA 2L1TA 4IRAA 3SWJA 4HX6A 3R5YA 2OL5A 1VL7A 3R5ZA 2A2JA 3R5LA 4HMXA 4YWNA 1USFA 3DMBA 1G76A 3R5RA 4HMWA 5BNCA 2VPAA 1YLNA 3VY5A 3PFTA 3ZOGA 3KYFA 3U0IA 1XXOA 4MTKA 1TY9A 3IN6A 2RE7A 3NFWA 3HY8A 2HTDA 4QVBA 2QEAA 1EJEA
chains in the Genus database with same CATH topology
2OU5A 3U35A 3AWHA 3ZOCA 2PTFA 1WLIA 3FKHA 4ZKYA 2E83A 2D36A 3TGVA 1G78A 1NRGA 2ASFA 3VYAA 3GASA 4HMSA 1XHNA 4YBNA 1I0RA 1T9MA 2IMLA 1Y30A 2D38A 1WGBA 3BA3A 3BNKA 2ECRA 2FG9A 1W3OA 1W3QA 3ZODA 3HMZA 2FURA 4F07A 2HQ7A 3A6QA 3KYGA 4HMUA 3RH7A 3B5MA 1DNLA 2X1KA 4HMTA 2ECUA 2R0XA 2ARZA 1WLKA 1USCA 4Y9IA 1W9AA 1WV4A 4Z85A 5ESCA 2GJGA 3BPKA 3E4VA 3U5WA 3K86A 2D37A 4R82A 2QCKA 3H96A 3ZOFA 3DB0A 5JABA 3AMFA 1RZ0A 4HMVA 3ZOEA 1RFEA 3CP3A 1AXJA 3K87A 3R5PA 1FLMA 2I51A 3FGEA 2ED4A 3VY2A 3A6RA 3DNHA 1G77A 1RZ1A 1JNWA 3A20A 2FHQA 3F7EA 5CHOA 2HHZA 1I0SA 1W3PA 3K88A 2R6VA 4XJ2A 2D5MA 3R5WA 2X1JA 1CI0A 4N7RC 3U34A 2RDEA 4L82A 2HQ9A 2IABA 1YOAA 2HTIA 2I02A 5CHEC 1G79A 3ZOHA 3CB0A 2Q9KA 2AQ6A 3EC6A 4XHYA 2IG6A 2NR4A 1W3RA 4IRAA 3SWJA 4HX6A 3R5YA 2OL5A 1VL7A 3R5ZA 2A2JA 3R5LA 4HMXA 4YWNA 1USFA 3DMBA 1G76A 3R5RA 4HMWA 5BNCA 2VPAA 1YLNA 3VY5A 3PFTA 3ZOGA 3KYFA 3U0IA 1XXOA 1TY9A 3IN6A 2RE7A 3NFWA 3HY8A 2HTDA 4QVBA 2QEAA 1EJEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OU5 A;  3U35 A;  3AWH A;  3ZOC A;  2PTF A;  1WLI A;  3FKH A;  4ZKY A;  2E83 A;  2D36 A;  3TGV A;  1G78 A;  1NRG A;  2ASF A;  3VYA A;  3GAS A;  4HMS A;  1XHN A;  4YBN A;  1I0R A;  1T9M A;  2IML A;  1Y30 A;  2D38 A;  1WGB A;  3BA3 A;  3BNK A;  2ECR A;  2FG9 A;  1W3O A;  1W3Q A;  3ZOD A;  3HMZ A;  2FUR A;  4F07 A;  2HQ7 A;  3A6Q A;  3KYG A;  4HMU A;  3RH7 A;  3B5M A;  1DNL A;  2X1K A;  4HMT A;  2ECU A;  2R0X A;  2ARZ A;  1WLK A;  1USC A;  4Y9I A;  1W9A A;  1WV4 A;  4Z85 A;  5ESC A;  2GJG A;  3BPK A;  3E4V A;  3U5W A;  3K86 A;  2D37 A;  4R82 A;  2QCK A;  3H96 A;  3ZOF A;  3DB0 A;  5JAB A;  3AMF A;  1RZ0 A;  4HMV A;  3ZOE A;  1RFE A;  3CP3 A;  1AXJ A;  3K87 A;  3R5P A;  1FLM A;  2I51 A;  3FGE A;  2ED4 A;  3VY2 A;  3A6R A;  3DNH A;  1G77 A;  1RZ1 A;  1JNW A;  3A20 A;  2FHQ A;  3F7E A;  5CHO A;  2HHZ A;  1I0S A;  1W3P A;  3K88 A;  2R6V A;  4XJ2 A;  2D5M A;  3R5W A;  2X1J A;  1CI0 A;  4N7R C;  3U34 A;  2RDE A;  4L82 A;  2HQ9 A;  2IAB A;  1YOA A;  2HTI A;  2I02 A;  5CHE C;  1G79 A;  3ZOH A;  3CB0 A;  2Q9K A;  2AQ6 A;  3EC6 A;  4XHY A;  2IG6 A;  2NR4 A;  1W3R A;  4IRA A;  3SWJ A;  4HX6 A;  3R5Y A;  2OL5 A;  1VL7 A;  3R5Z A;  2A2J A;  3R5L A;  4HMX A;  4YWN A;  1USF A;  3DMB A;  1G76 A;  3R5R A;  4HMW A;  5BNC A;  2VPA A;  1YLN A;  3VY5 A;  3PFT A;  3ZOG A;  3KYF A;  3U0I A;  1XXO A;  1TY9 A;  3IN6 A;  2RE7 A;  3NFW A;  3HY8 A;  2HTD A;  4QVB A;  2QEA A;  1EJE A; 
#chains in the Genus database with same CATH topology
 3V4H A;  2OU5 A;  3U35 A;  3AWH A;  3ZOC A;  2PTF A;  1WLI A;  3FKH A;  4ZKY A;  2E83 A;  2P5Z X;  2D36 A;  3TGV A;  1G78 A;  1NRG A;  2ASF A;  3VYA A;  3GAS A;  4HMS A;  1XHN A;  4YBN A;  1I0R A;  1T9M A;  2IML A;  4W64 A;  1Y30 A;  2D38 A;  1WGB A;  3BA3 A;  3BNK A;  2ECR A;  2FG9 A;  1W3O A;  1W3Q A;  3ZOD A;  3HMZ A;  2FUR A;  4F07 A;  2HQ7 A;  3A6Q A;  3KYG A;  4HMU A;  3RH7 A;  3B5M A;  1DNL A;  2X1K A;  4HMT A;  2ECU A;  2R0X A;  2ARZ A;  1WLK A;  1USC A;  4Y9I A;  1W9A A;  1WV4 A;  4TV4 A;  4Z85 A;  5ESC A;  2GJG A;  3BPK A;  3E4V A;  3U5W A;  4HKH A;  3K86 A;  2D37 A;  4UHV A;  4R82 A;  2QCK A;  3H96 A;  3ZOF A;  3DB0 A;  5JAB A;  3AMF A;  1RZ0 A;  4HMV A;  3ZOE A;  3HE1 A;  1RFE A;  3CP3 A;  1AXJ A;  3K87 A;  3R5P A;  1FLM A;  2I51 A;  3FGE A;  2ED4 A;  3VY2 A;  3A6R A;  3DNH A;  1G77 A;  1RZ1 A;  2GUJ A;  3EAA A;  1JNW A;  3A20 A;  2FHQ A;  3F7E A;  5CHO A;  2HHZ A;  1I0S A;  1W3P A;  3K88 A;  2R6V A;  4XJ2 A;  2D5M A;  3R5W A;  2X1J A;  1CI0 A;  4N7R C;  3U34 A;  2RDE A;  4L82 A;  2HQ9 A;  2IAB A;  1YOA A;  2HTI A;  2I02 A;  5CHE C;  1G79 A;  3ZOH A;  3CB0 A;  2K4Q A;  2Q9K A;  2AQ6 A;  1Y12 A;  3EC6 A;  4XHY A;  2IG6 A;  2NR4 A;  1W3R A;  2L1T A;  4IRA A;  3SWJ A;  4HX6 A;  3R5Y A;  2OL5 A;  1VL7 A;  3R5Z A;  2A2J A;  3R5L A;  4HMX A;  4YWN A;  1USF A;  3DMB A;  1G76 A;  3R5R A;  4HMW A;  5BNC A;  2VPA A;  1YLN A;  3VY5 A;  3PFT A;  3ZOG A;  3KYF A;  3U0I A;  1XXO A;  4MTK A;  1TY9 A;  3IN6 A;  2RE7 A;  3NFW A;  3HY8 A;  2HTD A;  4QVB A;  2QEA A;  1EJE A; 
#chains in the Genus database with same CATH homology
 2OU5 A;  3U35 A;  3AWH A;  3ZOC A;  2PTF A;  1WLI A;  3FKH A;  4ZKY A;  2E83 A;  2D36 A;  3TGV A;  1G78 A;  1NRG A;  2ASF A;  3VYA A;  3GAS A;  4HMS A;  1XHN A;  4YBN A;  1I0R A;  1T9M A;  2IML A;  1Y30 A;  2D38 A;  1WGB A;  3BA3 A;  3BNK A;  2ECR A;  2FG9 A;  1W3O A;  1W3Q A;  3ZOD A;  3HMZ A;  2FUR A;  4F07 A;  2HQ7 A;  3A6Q A;  3KYG A;  4HMU A;  3RH7 A;  3B5M A;  1DNL A;  2X1K A;  4HMT A;  2ECU A;  2R0X A;  2ARZ A;  1WLK A;  1USC A;  4Y9I A;  1W9A A;  1WV4 A;  4Z85 A;  5ESC A;  2GJG A;  3BPK A;  3E4V A;  3U5W A;  3K86 A;  2D37 A;  4R82 A;  2QCK A;  3H96 A;  3ZOF A;  3DB0 A;  5JAB A;  3AMF A;  1RZ0 A;  4HMV A;  3ZOE A;  1RFE A;  3CP3 A;  1AXJ A;  3K87 A;  3R5P A;  1FLM A;  2I51 A;  3FGE A;  2ED4 A;  3VY2 A;  3A6R A;  3DNH A;  1G77 A;  1RZ1 A;  1JNW A;  3A20 A;  2FHQ A;  3F7E A;  5CHO A;  2HHZ A;  1I0S A;  1W3P A;  3K88 A;  2R6V A;  4XJ2 A;  2D5M A;  3R5W A;  2X1J A;  1CI0 A;  4N7R C;  3U34 A;  2RDE A;  4L82 A;  2HQ9 A;  2IAB A;  1YOA A;  2HTI A;  2I02 A;  5CHE C;  1G79 A;  3ZOH A;  3CB0 A;  2Q9K A;  2AQ6 A;  3EC6 A;  4XHY A;  2IG6 A;  2NR4 A;  1W3R A;  4IRA A;  3SWJ A;  4HX6 A;  3R5Y A;  2OL5 A;  1VL7 A;  3R5Z A;  2A2J A;  3R5L A;  4HMX A;  4YWN A;  1USF A;  3DMB A;  1G76 A;  3R5R A;  4HMW A;  5BNC A;  2VPA A;  1YLN A;  3VY5 A;  3PFT A;  3ZOG A;  3KYF A;  3U0I A;  1XXO A;  1TY9 A;  3IN6 A;  2RE7 A;  3NFW A;  3HY8 A;  2HTD A;  4QVB A;  2QEA A;  1EJE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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