3R5WA

Structure of ddn, the deazaflavin-dependent nitroreductase from mycobacterium tuberculosis involved in bioreductive activation of pa-824, with co-factor f420
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
109
structure length
109
Chain Sequence
KIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis
molecule keywords Deazaflavin-dependent nitroreductase
total genus 31
structure length 109
sequence length 109
chains with identical sequence B, C, D, E, K, L, M, N, O
ec nomenclature ec 1.-.-.-:
pdb deposition date 2011-03-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.110.10 Mainly Beta Roll Pnp Oxidase; Chain A Electron Transport, Fmn-binding Protein; Chain A 3r5wA00
1I0RA 3A6QA 3CB0A 4IRAA 2QCKA 5BNCA 3U35A 3RH7A 3R5ZA 2I51A 1RZ1A 1XHNA 2IG6A 2ARZA 1W3RA 1RZ0A 3DB0A 3A20A 4HMVA 1USFA 3CP3A 3TGVA 1TY9A 2HTIA 4Z85A 3E4VA 1WLKA 3ZOGA 3AWHA 2QEAA 2D5MA 1I0SA 4ZKYA 3K86A 1DNLA 4HMTA 3HY8A 2D37A 3F7EA 1Y30A 3IN6A 2FHQA 1YOAA 3EC6A 3PFTA 4N7RC 2Q9KA 2HHZA 2R0XA 3VYAA 1W3QA 3KYFA 2GJGA 3BNKA 3R5PA 2ASFA 4HX6A 3ZODA 5JABA 3FKHA 4HMUA 3ZOCA 3KYGA 3GASA 2X1KA 3VY2A 1FLMA 3R5LA 1WLIA 1JNWA 4HMWA 4F07A 2IABA 2E83A 2I02A 2RDEA 1G76A 4YWNA 1W9AA 3A6RA 3R5RA 1EJEA 4HMXA 3R5WA 3R5YA 3DMBA 5ESCA 3BPKA 3K87A 1T9MA 4XJ2A 2OL5A 4QVBA 2D36A 1YLNA 1WGBA 3HMZA 4HMSA 3FGEA 2HQ7A 2ECUA 3SWJA 3ZOEA 2IMLA 1G77A 4Y9IA 2AQ6A 2ED4A 3H96A 1W3OA 3AMFA 4R82A 3ZOFA 1NRGA 3K88A 2HTDA 2FURA 1VL7A 1G78A 3NFWA 2X1JA 1USCA 3VY5A 1CI0A 2NR4A 1XXOA 1W3PA 2A2JA 1RFEA 4L82A 3U34A 2D38A 3B5MA 5CHEC 1G79A 2RE7A 4YBNA 2ECRA 3BA3A 2VPAA 2R6VA 2PTFA 3ZOHA 4XHYA 5CHOA 2FG9A 1WV4A 2HQ9A 2OU5A 3DNHA 3U5WA 1AXJA 3U0IA
chains in the Genus database with same CATH superfamily
1I0RA 3A6QA 4MTKA 2L1TA 3CB0A 4IRAA 2QCKA 5BNCA 3U35A 3RH7A 3R5ZA 2I51A 1RZ1A 1XHNA 2IG6A 2ARZA 1W3RA 1RZ0A 3DB0A 3A20A 4HMVA 1USFA 3CP3A 3TGVA 1TY9A 2HTIA 4Z85A 3E4VA 3U0IA 1WLKA 3ZOGA 3AWHA 2QEAA 2D5MA 1I0SA 4ZKYA 3K86A 1DNLA 4HMTA 3HY8A 2D37A 3F7EA 1Y30A 3IN6A 3HE1A 3V4HA 2FHQA 1YOAA 3EC6A 3PFTA 4N7RC 2Q9KA 2HHZA 2R0XA 3VYAA 1W3QA 3KYFA 2GJGA 3BNKA 3R5PA 2ASFA 4HX6A 2P5ZX 3ZODA 5JABA 3FKHA 4HMUA 3ZOCA 3KYGA 3GASA 2X1KA 3VY2A 1FLMA 3R5LA 1WLIA 1JNWA 4HMWA 4F07A 2IABA 2E83A 2I02A 2RDEA 1G76A 4YWNA 1W9AA 3A6RA 3R5RA 1EJEA 4HMXA 3R5WA 3R5YA 3DMBA 5ESCA 3BPKA 3K87A 1T9MA 4XJ2A 2OL5A 4QVBA 2D36A 1YLNA 1WGBA 3HMZA 4HMSA 3FGEA 2HQ7A 2ECUA 3SWJA 4HKHA 3ZOEA 2IMLA 3EAAA 1G77A 4Y9IA 2AQ6A 2ED4A 3H96A 1W3OA 3AMFA 4R82A 3ZOFA 1NRGA 2GUJA 3K88A 2HTDA 2FURA 1VL7A 1G78A 3NFWA 2X1JA 4W64A 1USCA 3VY5A 1CI0A 2NR4A 1XXOA 2K4QA 1Y12A 1W3PA 2A2JA 1RFEA 4L82A 3U34A 2D38A 3B5MA 5CHEC 1G79A 2RE7A 4YBNA 2ECRA 3BA3A 2VPAA 2R6VA 2PTFA 3ZOHA 4XHYA 5CHOA 4TV4A 2FG9A 1WV4A 2HQ9A 2OU5A 3DNHA 3U5WA 1AXJA 4UHVA
chains in the Genus database with same CATH topology
1I0RA 3A6QA 3CB0A 4IRAA 2QCKA 5BNCA 3U35A 3RH7A 3R5ZA 2I51A 1RZ1A 1XHNA 2IG6A 2ARZA 1W3RA 1RZ0A 3DB0A 3A20A 4HMVA 1USFA 3CP3A 3TGVA 1TY9A 2HTIA 4Z85A 3E4VA 1WLKA 3ZOGA 3AWHA 2QEAA 2D5MA 1I0SA 4ZKYA 3K86A 1DNLA 4HMTA 3HY8A 2D37A 3F7EA 1Y30A 3IN6A 2FHQA 1YOAA 3EC6A 3PFTA 4N7RC 2Q9KA 2HHZA 2R0XA 3VYAA 1W3QA 3KYFA 2GJGA 3BNKA 3R5PA 2ASFA 4HX6A 3ZODA 5JABA 3FKHA 4HMUA 3ZOCA 3KYGA 3GASA 2X1KA 3VY2A 1FLMA 3R5LA 1WLIA 1JNWA 4HMWA 4F07A 2IABA 2E83A 2I02A 2RDEA 1G76A 4YWNA 1W9AA 3A6RA 3R5RA 1EJEA 4HMXA 3R5WA 3R5YA 3DMBA 5ESCA 3BPKA 3K87A 1T9MA 4XJ2A 2OL5A 4QVBA 2D36A 1YLNA 1WGBA 3HMZA 4HMSA 3FGEA 2HQ7A 2ECUA 3SWJA 3ZOEA 2IMLA 1G77A 4Y9IA 2AQ6A 2ED4A 3H96A 1W3OA 3AMFA 4R82A 3ZOFA 1NRGA 3K88A 2HTDA 2FURA 1VL7A 1G78A 3NFWA 2X1JA 1USCA 3VY5A 1CI0A 2NR4A 1XXOA 1W3PA 2A2JA 1RFEA 4L82A 3U34A 2D38A 3B5MA 5CHEC 1G79A 2RE7A 4YBNA 2ECRA 3BA3A 2VPAA 2R6VA 2PTFA 3ZOHA 4XHYA 5CHOA 2FG9A 1WV4A 2HQ9A 2OU5A 3DNHA 3U5WA 1AXJA 3U0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I0R A;  3A6Q A;  3CB0 A;  4IRA A;  2QCK A;  5BNC A;  3U35 A;  3RH7 A;  3R5Z A;  2I51 A;  1RZ1 A;  1XHN A;  2IG6 A;  2ARZ A;  1W3R A;  1RZ0 A;  3DB0 A;  3A20 A;  4HMV A;  1USF A;  3CP3 A;  3TGV A;  1TY9 A;  2HTI A;  4Z85 A;  3E4V A;  1WLK A;  3ZOG A;  3AWH A;  2QEA A;  2D5M A;  1I0S A;  4ZKY A;  3K86 A;  1DNL A;  4HMT A;  3HY8 A;  2D37 A;  3F7E A;  1Y30 A;  3IN6 A;  2FHQ A;  1YOA A;  3EC6 A;  3PFT A;  4N7R C;  2Q9K A;  2HHZ A;  2R0X A;  3VYA A;  1W3Q A;  3KYF A;  2GJG A;  3BNK A;  3R5P A;  2ASF A;  4HX6 A;  3ZOD A;  5JAB A;  3FKH A;  4HMU A;  3ZOC A;  3KYG A;  3GAS A;  2X1K A;  3VY2 A;  1FLM A;  3R5L A;  1WLI A;  1JNW A;  4HMW A;  4F07 A;  2IAB A;  2E83 A;  2I02 A;  2RDE A;  1G76 A;  4YWN A;  1W9A A;  3A6R A;  3R5R A;  1EJE A;  4HMX A;  3R5W A;  3R5Y A;  3DMB A;  5ESC A;  3BPK A;  3K87 A;  1T9M A;  4XJ2 A;  2OL5 A;  4QVB A;  2D36 A;  1YLN A;  1WGB A;  3HMZ A;  4HMS A;  3FGE A;  2HQ7 A;  2ECU A;  3SWJ A;  3ZOE A;  2IML A;  1G77 A;  4Y9I A;  2AQ6 A;  2ED4 A;  3H96 A;  1W3O A;  3AMF A;  4R82 A;  3ZOF A;  1NRG A;  3K88 A;  2HTD A;  2FUR A;  1VL7 A;  1G78 A;  3NFW A;  2X1J A;  1USC A;  3VY5 A;  1CI0 A;  2NR4 A;  1XXO A;  1W3P A;  2A2J A;  1RFE A;  4L82 A;  3U34 A;  2D38 A;  3B5M A;  5CHE C;  1G79 A;  2RE7 A;  4YBN A;  2ECR A;  3BA3 A;  2VPA A;  2R6V A;  2PTF A;  3ZOH A;  4XHY A;  5CHO A;  2FG9 A;  1WV4 A;  2HQ9 A;  2OU5 A;  3DNH A;  3U5W A;  1AXJ A;  3U0I A; 
#chains in the Genus database with same CATH topology
 1I0R A;  3A6Q A;  4MTK A;  2L1T A;  3CB0 A;  4IRA A;  2QCK A;  5BNC A;  3U35 A;  3RH7 A;  3R5Z A;  2I51 A;  1RZ1 A;  1XHN A;  2IG6 A;  2ARZ A;  1W3R A;  1RZ0 A;  3DB0 A;  3A20 A;  4HMV A;  1USF A;  3CP3 A;  3TGV A;  1TY9 A;  2HTI A;  4Z85 A;  3E4V A;  3U0I A;  1WLK A;  3ZOG A;  3AWH A;  2QEA A;  2D5M A;  1I0S A;  4ZKY A;  3K86 A;  1DNL A;  4HMT A;  3HY8 A;  2D37 A;  3F7E A;  1Y30 A;  3IN6 A;  3HE1 A;  3V4H A;  2FHQ A;  1YOA A;  3EC6 A;  3PFT A;  4N7R C;  2Q9K A;  2HHZ A;  2R0X A;  3VYA A;  1W3Q A;  3KYF A;  2GJG A;  3BNK A;  3R5P A;  2ASF A;  4HX6 A;  2P5Z X;  3ZOD A;  5JAB A;  3FKH A;  4HMU A;  3ZOC A;  3KYG A;  3GAS A;  2X1K A;  3VY2 A;  1FLM A;  3R5L A;  1WLI A;  1JNW A;  4HMW A;  4F07 A;  2IAB A;  2E83 A;  2I02 A;  2RDE A;  1G76 A;  4YWN A;  1W9A A;  3A6R A;  3R5R A;  1EJE A;  4HMX A;  3R5W A;  3R5Y A;  3DMB A;  5ESC A;  3BPK A;  3K87 A;  1T9M A;  4XJ2 A;  2OL5 A;  4QVB A;  2D36 A;  1YLN A;  1WGB A;  3HMZ A;  4HMS A;  3FGE A;  2HQ7 A;  2ECU A;  3SWJ A;  4HKH A;  3ZOE A;  2IML A;  3EAA A;  1G77 A;  4Y9I A;  2AQ6 A;  2ED4 A;  3H96 A;  1W3O A;  3AMF A;  4R82 A;  3ZOF A;  1NRG A;  2GUJ A;  3K88 A;  2HTD A;  2FUR A;  1VL7 A;  1G78 A;  3NFW A;  2X1J A;  4W64 A;  1USC A;  3VY5 A;  1CI0 A;  2NR4 A;  1XXO A;  2K4Q A;  1Y12 A;  1W3P A;  2A2J A;  1RFE A;  4L82 A;  3U34 A;  2D38 A;  3B5M A;  5CHE C;  1G79 A;  2RE7 A;  4YBN A;  2ECR A;  3BA3 A;  2VPA A;  2R6V A;  2PTF A;  3ZOH A;  4XHY A;  5CHO A;  4TV4 A;  2FG9 A;  1WV4 A;  2HQ9 A;  2OU5 A;  3DNH A;  3U5W A;  1AXJ A;  4UHV A; 
#chains in the Genus database with same CATH homology
 1I0R A;  3A6Q A;  3CB0 A;  4IRA A;  2QCK A;  5BNC A;  3U35 A;  3RH7 A;  3R5Z A;  2I51 A;  1RZ1 A;  1XHN A;  2IG6 A;  2ARZ A;  1W3R A;  1RZ0 A;  3DB0 A;  3A20 A;  4HMV A;  1USF A;  3CP3 A;  3TGV A;  1TY9 A;  2HTI A;  4Z85 A;  3E4V A;  1WLK A;  3ZOG A;  3AWH A;  2QEA A;  2D5M A;  1I0S A;  4ZKY A;  3K86 A;  1DNL A;  4HMT A;  3HY8 A;  2D37 A;  3F7E A;  1Y30 A;  3IN6 A;  2FHQ A;  1YOA A;  3EC6 A;  3PFT A;  4N7R C;  2Q9K A;  2HHZ A;  2R0X A;  3VYA A;  1W3Q A;  3KYF A;  2GJG A;  3BNK A;  3R5P A;  2ASF A;  4HX6 A;  3ZOD A;  5JAB A;  3FKH A;  4HMU A;  3ZOC A;  3KYG A;  3GAS A;  2X1K A;  3VY2 A;  1FLM A;  3R5L A;  1WLI A;  1JNW A;  4HMW A;  4F07 A;  2IAB A;  2E83 A;  2I02 A;  2RDE A;  1G76 A;  4YWN A;  1W9A A;  3A6R A;  3R5R A;  1EJE A;  4HMX A;  3R5W A;  3R5Y A;  3DMB A;  5ESC A;  3BPK A;  3K87 A;  1T9M A;  4XJ2 A;  2OL5 A;  4QVB A;  2D36 A;  1YLN A;  1WGB A;  3HMZ A;  4HMS A;  3FGE A;  2HQ7 A;  2ECU A;  3SWJ A;  3ZOE A;  2IML A;  1G77 A;  4Y9I A;  2AQ6 A;  2ED4 A;  3H96 A;  1W3O A;  3AMF A;  4R82 A;  3ZOF A;  1NRG A;  3K88 A;  2HTD A;  2FUR A;  1VL7 A;  1G78 A;  3NFW A;  2X1J A;  1USC A;  3VY5 A;  1CI0 A;  2NR4 A;  1XXO A;  1W3P A;  2A2J A;  1RFE A;  4L82 A;  3U34 A;  2D38 A;  3B5M A;  5CHE C;  1G79 A;  2RE7 A;  4YBN A;  2ECR A;  3BA3 A;  2VPA A;  2R6V A;  2PTF A;  3ZOH A;  4XHY A;  5CHO A;  2FG9 A;  1WV4 A;  2HQ9 A;  2OU5 A;  3DNH A;  3U5W A;  1AXJ A;  3U0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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