1LQ8A

Crystal structure of cleaved protein c inhibitor
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
329
structure length
329
Chain Sequence
RRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation
pubmed doi rcsb
molecule tags Blood clotting
molecule keywords plasma serine protease inhibitor
total genus 94
structure length 329
sequence length 329
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2002-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 1lq8A01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 1lq8A02
3DRUA 5CDXA 3PZFA 1HP7A 1QLPA 1LJ5A 4P0FA 3PB1I 1KCTA 1EZXA 3FGQA 1HLEA 3EOXA 3Q02A 4ZK0A 2B4XI 3CWLA 3F1SA 4EB1L 5EI0A 1JTIA 4AU3A 1ATTA 4DY0A 2ANTI 3H5CA 3R4LA 1DVMA 4C49A 3NDAA 5C98A 9APIA 1OO8A 2WXXA 4C41A 7APIA 3EVJI 3STOA 1DZGI 2OAYA 2XN6A 4AQHA 1UHGA 2WXYC 1BR8I 3CWMA 2VDXA 3T1PA 3ZHAA 3KCGI 4X30A 1E03I 1PSIA 1QMNA 2H4QA 2PEEA 1ANTI 2B4XL 2ZNHA 1DB2A 1YXAA 3OZQA 1LQ8A 4ROBA 4ZK3A 1SR5A 2WXZC 1B3KA 4AJUA 1OYHI 1C5GA 3LW2A 4PYWA 3F02A 1BY7A 1DZGL 1M93B 1AS4A 1OPHA 2V95A 4G8OA 1XQJA 3VVJA 5BRRI 2H4RA 5IO1A 1DZHI 1A7CA 2B5TI 2XN5A 5HGCA 1WZ9A 1C8OA 4Y3KA 4CAAA 2GD4C 4P0OA 2HIJI 3NE4A 1OC0A 2ARRA 1OYHL 1ATUA 1JRRA 2RIVA 2WY1A 3UT3A 1K9OI 2DUTA 1AZXI 2HI9A 3DLWA 4Y40A 4AU4A 4IF8A 1NQ9I 1TB6I 4AU2A 5CDZA 1SNGA 2BEHI 1DZHL 1OVAC 3CAAA 3B9FI 4ROAA 1SEKA 4R9IA 1ATHA 2PEFA 2VH4A 8APIA 1OVAB 2HIJL 4KDSA 4DY7C 4AFXA 5INWA 4GA7A 3DY0A 1T1FA 2ACHA 1IMVA 2D26A 4IC0A 1F0CA 1XU8A 2BEHL 4RSQA 2R9YA 3F5NA 2OL2A 1MTPA 5CE0A 4G8RA 2RIWA 3DRMA 1DVNA 4AJTA 2ARQA 1QMBA 3NDDA 4AU3B 1JMJA 9PAIA 1R1LI 1IZ2A 1JJOC 2VDYA 1XQGA 3NDFA 2WXWA 4BB2A 4RO9A 1E04I 1LK6I 1JVQI 1OVAA 2WXZA 2XN7A 3LE2A 2CEOA 2H4PA 1JMOA 4DTEA 4EB1I 3CVMA 4YIAA 2WY0C 2QUGA 1D5SA 2ZV6A 2XN3A 1E05I 3Q03A
chains in the Genus database with same CATH superfamily
3DRUA 5CDXA 3PZFA 1HP7A 1QLPA 1LJ5A 4P0FA 3PB1I 1KCTA 1EZXA 3FGQA 1HLEA 3EOXA 3Q02A 4ZK0A 2B4XI 3CWLA 3F1SA 4EB1L 5EI0A 1JTIA 4AU3A 1ATTA 4DY0A 2ANTI 3H5CA 3R4LA 1DVMA 4C49A 3NDAA 5C98A 9APIA 1OO8A 2WXXA 4C41A 7APIA 3EVJI 3STOA 1DZGI 2OAYA 2XN6A 4AQHA 1UHGA 2WXYC 1BR8I 3CWMA 2VDXA 3T1PA 3ZHAA 3KCGI 4X30A 1E03I 1PSIA 1QMNA 2H4QA 2PEEA 1ANTI 2B4XL 2ZNHA 1DB2A 1YXAA 3OZQA 1LQ8A 4ROBA 4ZK3A 1SR5A 2WXZC 1B3KA 4AJUA 1OYHI 1C5GA 3LW2A 4PYWA 3F02A 1BY7A 1DZGL 1M93B 1AS4A 1OPHA 2V95A 4G8OA 1XQJA 3VVJA 5BRRI 2H4RA 5IO1A 1DZHI 1A7CA 2B5TI 2XN5A 5HGCA 1WZ9A 1C8OA 4Y3KA 4CAAA 2GD4C 4P0OA 2HIJI 3NE4A 1OC0A 2ARRA 1OYHL 1ATUA 1JRRA 2RIVA 2WY1A 3UT3A 1K9OI 2DUTA 1AZXI 2HI9A 3DLWA 4Y40A 4AU4A 4IF8A 1NQ9I 1TB6I 4AU2A 5CDZA 1SNGA 2BEHI 1DZHL 1OVAC 3CAAA 3B9FI 4ROAA 1SEKA 4R9IA 1ATHA 2PEFA 2VH4A 8APIA 1OVAB 2HIJL 4KDSA 4DY7C 4AFXA 5INWA 4GA7A 3DY0A 1T1FA 2ACHA 1IMVA 2D26A 4IC0A 1F0CA 1XU8A 2BEHL 4RSQA 2R9YA 3F5NA 2OL2A 1MTPA 5CE0A 4G8RA 2RIWA 3DRMA 1DVNA 4AJTA 2ARQA 1QMBA 3NDDA 4AU3B 1JMJA 9PAIA 1R1LI 1IZ2A 1JJOC 2VDYA 1XQGA 3NDFA 2WXWA 4BB2A 4RO9A 1E04I 1LK6I 1JVQI 1OVAA 2WXZA 2XN7A 3LE2A 2CEOA 2H4PA 1JMOA 4DTEA 4EB1I 3CVMA 4YIAA 2WY0C 2QUGA 1D5SA 2ZV6A 2XN3A 1E05I 3Q03A
chains in the Genus database with same CATH topology
3DRUA 5CDXA 3PZFA 1HP7A 1QLPA 1LJ5A 4P0FA 3PB1I 1KCTA 1EZXA 3FGQA 1HLEA 3EOXA 3Q02A 4ZK0A 2B4XI 3CWLA 3F1SA 4EB1L 5EI0A 1JTIA 4AU3A 1ATTA 4DY0A 2ANTI 3H5CA 3R4LA 1DVMA 4C49A 3NDAA 5C98A 9APIA 1OO8A 2WXXA 4C41A 7APIA 3EVJI 3STOA 1DZGI 2OAYA 2XN6A 4AQHA 1UHGA 2WXYC 1BR8I 3CWMA 2VDXA 3T1PA 3ZHAA 3KCGI 4X30A 1E03I 1PSIA 1QMNA 2H4QA 2PEEA 1ANTI 2B4XL 2ZNHA 1DB2A 1YXAA 3OZQA 1LQ8A 4ROBA 4ZK3A 1SR5A 2WXZC 1B3KA 4AJUA 1OYHI 1C5GA 3LW2A 4PYWA 3F02A 1BY7A 1DZGL 1M93B 1AS4A 1OPHA 2V95A 4G8OA 1XQJA 3VVJA 5BRRI 2H4RA 5IO1A 1DZHI 1A7CA 2B5TI 2XN5A 5HGCA 1WZ9A 1C8OA 4Y3KA 4CAAA 2GD4C 4P0OA 2HIJI 3NE4A 1OC0A 2ARRA 1OYHL 1ATUA 1JRRA 2RIVA 2WY1A 3UT3A 1K9OI 2DUTA 1AZXI 2HI9A 3DLWA 4Y40A 4AU4A 4IF8A 1NQ9I 1TB6I 4AU2A 5CDZA 1SNGA 2BEHI 1DZHL 1OVAC 3CAAA 3B9FI 4ROAA 1SEKA 4R9IA 1ATHA 2PEFA 2VH4A 8APIA 1OVAB 2HIJL 4KDSA 4DY7C 4AFXA 5INWA 4GA7A 3DY0A 1T1FA 2ACHA 1IMVA 2D26A 4IC0A 1F0CA 1XU8A 2BEHL 4RSQA 2R9YA 3F5NA 2OL2A 1MTPA 5CE0A 4G8RA 2RIWA 3DRMA 1DVNA 4AJTA 2ARQA 1QMBA 3NDDA 4AU3B 1JMJA 9PAIA 1R1LI 1IZ2A 1JJOC 2VDYA 1XQGA 3NDFA 2WXWA 4BB2A 4RO9A 1E04I 1LK6I 1JVQI 1OVAA 2WXZA 2XN7A 3LE2A 2CEOA 2H4PA 1JMOA 4DTEA 4EB1I 3CVMA 4YIAA 2WY0C 2QUGA 1D5SA 2ZV6A 2XN3A 1E05I 3Q03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DRU A;  5CDX A;  3PZF A;  1HP7 A;  1QLP A;  1LJ5 A;  4P0F A;  3PB1 I;  1KCT A;  1EZX A;  3FGQ A;  1HLE A;  3EOX A;  3Q02 A;  4ZK0 A;  2B4X I;  3CWL A;  3F1S A;  4EB1 L;  5EI0 A;  1JTI A;  4AU3 A;  1ATT A;  4DY0 A;  2ANT I;  3H5C A;  3R4L A;  1DVM A;  4C49 A;  3NDA A;  5C98 A;  9API A;  1OO8 A;  2WXX A;  4C41 A;  7API A;  3EVJ I;  3STO A;  1DZG I;  2OAY A;  2XN6 A;  4AQH A;  1UHG A;  2WXY C;  1BR8 I;  3CWM A;  2VDX A;  3T1P A;  3ZHA A;  3KCG I;  4X30 A;  1E03 I;  1PSI A;  1QMN A;  2H4Q A;  2PEE A;  1ANT I;  2B4X L;  2ZNH A;  1DB2 A;  1YXA A;  3OZQ A;  1LQ8 A;  4ROB A;  4ZK3 A;  1SR5 A;  2WXZ C;  1B3K A;  4AJU A;  1OYH I;  1C5G A;  3LW2 A;  4PYW A;  3F02 A;  1BY7 A;  1DZG L;  1M93 B;  1AS4 A;  1OPH A;  2V95 A;  4G8O A;  1XQJ A;  3VVJ A;  5BRR I;  2H4R A;  5IO1 A;  1DZH I;  1A7C A;  2B5T I;  2XN5 A;  5HGC A;  1WZ9 A;  1C8O A;  4Y3K A;  4CAA A;  2GD4 C;  4P0O A;  2HIJ I;  3NE4 A;  1OC0 A;  2ARR A;  1OYH L;  1ATU A;  1JRR A;  2RIV A;  2WY1 A;  3UT3 A;  1K9O I;  2DUT A;  1AZX I;  2HI9 A;  3DLW A;  4Y40 A;  4AU4 A;  4IF8 A;  1NQ9 I;  1TB6 I;  4AU2 A;  5CDZ A;  1SNG A;  2BEH I;  1DZH L;  1OVA C;  3CAA A;  3B9F I;  4ROA A;  1SEK A;  4R9I A;  1ATH A;  2PEF A;  2VH4 A;  8API A;  1OVA B;  2HIJ L;  4KDS A;  4DY7 C;  4AFX A;  5INW A;  4GA7 A;  3DY0 A;  1T1F A;  2ACH A;  1IMV A;  2D26 A;  4IC0 A;  1F0C A;  1XU8 A;  2BEH L;  4RSQ A;  2R9Y A;  3F5N A;  2OL2 A;  1MTP A;  5CE0 A;  4G8R A;  2RIW A;  3DRM A;  1DVN A;  4AJT A;  2ARQ A;  1QMB A;  3NDD A;  4AU3 B;  1JMJ A;  9PAI A;  1R1L I;  1IZ2 A;  1JJO C;  2VDY A;  1XQG A;  3NDF A;  2WXW A;  4BB2 A;  4RO9 A;  1E04 I;  1LK6 I;  1JVQ I;  1OVA A;  2WXZ A;  2XN7 A;  3LE2 A;  2CEO A;  2H4P A;  1JMO A;  4DTE A;  4EB1 I;  3CVM A;  4YIA A;  2WY0 C;  2QUG A;  1D5S A;  2ZV6 A;  2XN3 A;  1E05 I;  3Q03 A; 
#chains in the Genus database with same CATH topology
 3DRU A;  5CDX A;  3PZF A;  1HP7 A;  1QLP A;  1LJ5 A;  4P0F A;  3PB1 I;  1KCT A;  1EZX A;  3FGQ A;  1HLE A;  3EOX A;  3Q02 A;  4ZK0 A;  2B4X I;  3CWL A;  3F1S A;  4EB1 L;  5EI0 A;  1JTI A;  4AU3 A;  1ATT A;  4DY0 A;  2ANT I;  3H5C A;  3R4L A;  1DVM A;  4C49 A;  3NDA A;  5C98 A;  9API A;  1OO8 A;  2WXX A;  4C41 A;  7API A;  3EVJ I;  3STO A;  1DZG I;  2OAY A;  2XN6 A;  4AQH A;  1UHG A;  2WXY C;  1BR8 I;  3CWM A;  2VDX A;  3T1P A;  3ZHA A;  3KCG I;  4X30 A;  1E03 I;  1PSI A;  1QMN A;  2H4Q A;  2PEE A;  1ANT I;  2B4X L;  2ZNH A;  1DB2 A;  1YXA A;  3OZQ A;  1LQ8 A;  4ROB A;  4ZK3 A;  1SR5 A;  2WXZ C;  1B3K A;  4AJU A;  1OYH I;  1C5G A;  3LW2 A;  4PYW A;  3F02 A;  1BY7 A;  1DZG L;  1M93 B;  1AS4 A;  1OPH A;  2V95 A;  4G8O A;  1XQJ A;  3VVJ A;  5BRR I;  2H4R A;  5IO1 A;  1DZH I;  1A7C A;  2B5T I;  2XN5 A;  5HGC A;  1WZ9 A;  1C8O A;  4Y3K A;  4CAA A;  2GD4 C;  4P0O A;  2HIJ I;  3NE4 A;  1OC0 A;  2ARR A;  1OYH L;  1ATU A;  1JRR A;  2RIV A;  2WY1 A;  3UT3 A;  1K9O I;  2DUT A;  1AZX I;  2HI9 A;  3DLW A;  4Y40 A;  4AU4 A;  4IF8 A;  1NQ9 I;  1TB6 I;  4AU2 A;  5CDZ A;  1SNG A;  2BEH I;  1DZH L;  1OVA C;  3CAA A;  3B9F I;  4ROA A;  1SEK A;  4R9I A;  1ATH A;  2PEF A;  2VH4 A;  8API A;  1OVA B;  2HIJ L;  4KDS A;  4DY7 C;  4AFX A;  5INW A;  4GA7 A;  3DY0 A;  1T1F A;  2ACH A;  1IMV A;  2D26 A;  4IC0 A;  1F0C A;  1XU8 A;  2BEH L;  4RSQ A;  2R9Y A;  3F5N A;  2OL2 A;  1MTP A;  5CE0 A;  4G8R A;  2RIW A;  3DRM A;  1DVN A;  4AJT A;  2ARQ A;  1QMB A;  3NDD A;  4AU3 B;  1JMJ A;  9PAI A;  1R1L I;  1IZ2 A;  1JJO C;  2VDY A;  1XQG A;  3NDF A;  2WXW A;  4BB2 A;  4RO9 A;  1E04 I;  1LK6 I;  1JVQ I;  1OVA A;  2WXZ A;  2XN7 A;  3LE2 A;  2CEO A;  2H4P A;  1JMO A;  4DTE A;  4EB1 I;  3CVM A;  4YIA A;  2WY0 C;  2QUG A;  1D5S A;  2ZV6 A;  2XN3 A;  1E05 I;  3Q03 A; 
#chains in the Genus database with same CATH homology
 3DRU A;  5CDX A;  3PZF A;  1HP7 A;  1QLP A;  1LJ5 A;  4P0F A;  3PB1 I;  1KCT A;  1EZX A;  3FGQ A;  1HLE A;  3EOX A;  3Q02 A;  4ZK0 A;  2B4X I;  3CWL A;  3F1S A;  4EB1 L;  5EI0 A;  1JTI A;  4AU3 A;  1ATT A;  4DY0 A;  2ANT I;  3H5C A;  3R4L A;  1DVM A;  4C49 A;  3NDA A;  5C98 A;  9API A;  1OO8 A;  2WXX A;  4C41 A;  7API A;  3EVJ I;  3STO A;  1DZG I;  2OAY A;  2XN6 A;  4AQH A;  1UHG A;  2WXY C;  1BR8 I;  3CWM A;  2VDX A;  3T1P A;  3ZHA A;  3KCG I;  4X30 A;  1E03 I;  1PSI A;  1QMN A;  2H4Q A;  2PEE A;  1ANT I;  2B4X L;  2ZNH A;  1DB2 A;  1YXA A;  3OZQ A;  1LQ8 A;  4ROB A;  4ZK3 A;  1SR5 A;  2WXZ C;  1B3K A;  4AJU A;  1OYH I;  1C5G A;  3LW2 A;  4PYW A;  3F02 A;  1BY7 A;  1DZG L;  1M93 B;  1AS4 A;  1OPH A;  2V95 A;  4G8O A;  1XQJ A;  3VVJ A;  5BRR I;  2H4R A;  5IO1 A;  1DZH I;  1A7C A;  2B5T I;  2XN5 A;  5HGC A;  1WZ9 A;  1C8O A;  4Y3K A;  4CAA A;  2GD4 C;  4P0O A;  2HIJ I;  3NE4 A;  1OC0 A;  2ARR A;  1OYH L;  1ATU A;  1JRR A;  2RIV A;  2WY1 A;  3UT3 A;  1K9O I;  2DUT A;  1AZX I;  2HI9 A;  3DLW A;  4Y40 A;  4AU4 A;  4IF8 A;  1NQ9 I;  1TB6 I;  4AU2 A;  5CDZ A;  1SNG A;  2BEH I;  1DZH L;  1OVA C;  3CAA A;  3B9F I;  4ROA A;  1SEK A;  4R9I A;  1ATH A;  2PEF A;  2VH4 A;  8API A;  1OVA B;  2HIJ L;  4KDS A;  4DY7 C;  4AFX A;  5INW A;  4GA7 A;  3DY0 A;  1T1F A;  2ACH A;  1IMV A;  2D26 A;  4IC0 A;  1F0C A;  1XU8 A;  2BEH L;  4RSQ A;  2R9Y A;  3F5N A;  2OL2 A;  1MTP A;  5CE0 A;  4G8R A;  2RIW A;  3DRM A;  1DVN A;  4AJT A;  2ARQ A;  1QMB A;  3NDD A;  4AU3 B;  1JMJ A;  9PAI A;  1R1L I;  1IZ2 A;  1JJO C;  2VDY A;  1XQG A;  3NDF A;  2WXW A;  4BB2 A;  4RO9 A;  1E04 I;  1LK6 I;  1JVQ I;  1OVA A;  2WXZ A;  2XN7 A;  3LE2 A;  2CEO A;  2H4P A;  1JMO A;  4DTE A;  4EB1 I;  3CVM A;  4YIA A;  2WY0 C;  2QUG A;  1D5S A;  2ZV6 A;  2XN3 A;  1E05 I;  3Q03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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