4BB2A

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
337
structure length
332
Chain Sequence
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
pubmed doi rcsb
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
molecule tags Transport protein
source organism Homo sapiens
total genus 98
structure length 332
sequence length 337
ec nomenclature
pdb deposition date 2012-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4bb2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4bb2A01
2B4XI 1LJ5A 2ANTI 3T1PA 2D26A 2XN6A 2B4XL 4EB1L 2WXXA 2H4QA 2ARQA 4C49A 1OC0A 1ATTA 1DZHL 1SR5A 3VVJA 3ZHAA 3STOA 5CDXA 1JVQI 1DZGL 1XQJA 4IC0A 3DLWA 9APIA 1DVNA 1E04I 2PEFA 1C5GA 2WXWA 4AU4A 3PB1I 1D5SA 2DUTA 1BR8I 3DRMA 4AU2A 1IMVA 2ARRA 1JMJA 2PEEA 1T1FA 4C41A 4DY7C 1E03I 4AJTA 4R9IA 2VDXA 3CWLA 4RO9A 1AS4A 1F0CA 3CWMA 1OYHI 2VDYA 2R9YA 3F5NA 4CAAA 4Y3KA 4EB1I 5CE0A 1WZ9A 2ZV6A 3H5CA 4G8OA 1QMBA 2RIWA 1OYHL 1DB2A 4X30A 9PAIA 1DZHI 1QLPA 3PZFA 2HIJI 2QUGA 3OZQA 1DZGI 2CEOA 2HIJL 3UT3A 2ACHA 2WXZC 1AZXI 1C8OA 4AU3B 2V95A 3NDDA 1JTIA 3B9FI 3NDFA 1IZ2A 1BY7A 1ATHA 1MTPA 2H4RA 3DY0A 3Q02A 3F1SA 1K9OI 7APIA 1B3KA 4IF8A 4PYWA 2WXYC 3DRUA 1JJOC 3KCGI 2XN7A 4BB2A 2VH4A 2ZNHA 3CVMA 1HP7A 4P0OA 4DTEA 4G8RA 1NQ9I 4Y40A 1KCTA 2BEHI 3CAAA 1JRRA 1SEKA 1UHGA 2BEHL 2WY0C 3EVJI 1EZXA 2XN5A 2WXZA 1XQGA 4ZK0A 3F02A 1ANTI 4AU3A 4ZK3A 8APIA 1DVMA 5CDZA 1OVAB 1QMNA 3NE4A 1LK6I 1OVAC 3LE2A 3NDAA 2B5TI 2RIVA 1A7CA 1HLEA 4GA7A 1E05I 4ROBA 5INWA 4YIAA 4KDSA 4ROAA 1TB6I 4AQHA 2OAYA 5IO1A 4RSQA 1OO8A 5EI0A 2XN3A 1ATUA 1JMOA 2OL2A 2WY1A 1R1LI 1YXAA 2HI9A 3EOXA 3FGQA 5HGCA 1M93B 1OPHA 3Q03A 4AFXA 2H4PA 1LQ8A 3R4LA 4AJUA 1SNGA 1OVAA 2GD4C 5C98A 4DY0A 1PSIA 4P0FA 1XU8A 5BRRI 3LW2A
chains in the Genus database with same CATH superfamily
2B4XI 1LJ5A 2ANTI 3T1PA 2D26A 2XN6A 2B4XL 4EB1L 2WXXA 2H4QA 2ARQA 4C49A 1OC0A 1ATTA 1DZHL 1SR5A 3VVJA 3ZHAA 3STOA 5CDXA 1JVQI 1DZGL 1XQJA 4IC0A 3DLWA 9APIA 1DVNA 1E04I 2PEFA 1C5GA 2WXWA 4AU4A 3PB1I 1D5SA 2DUTA 1BR8I 3DRMA 4AU2A 1IMVA 2ARRA 1JMJA 2PEEA 1T1FA 4C41A 4DY7C 1E03I 4AJTA 4R9IA 2VDXA 3CWLA 4RO9A 1AS4A 1F0CA 3CWMA 1OYHI 2VDYA 2R9YA 3F5NA 4CAAA 4Y3KA 4EB1I 5CE0A 1WZ9A 2ZV6A 3H5CA 4G8OA 1QMBA 2RIWA 1OYHL 1DB2A 4X30A 9PAIA 1DZHI 1QLPA 3PZFA 2HIJI 2QUGA 3OZQA 1DZGI 2CEOA 2HIJL 3UT3A 2ACHA 2WXZC 1AZXI 1C8OA 4AU3B 2V95A 3NDDA 1JTIA 3B9FI 3NDFA 1IZ2A 1BY7A 1ATHA 1MTPA 2H4RA 3DY0A 3Q02A 3F1SA 1K9OI 7APIA 1B3KA 4IF8A 4PYWA 2WXYC 3DRUA 1JJOC 3KCGI 2XN7A 4BB2A 2VH4A 2ZNHA 3CVMA 1HP7A 4P0OA 4DTEA 4G8RA 1NQ9I 4Y40A 1KCTA 2BEHI 3CAAA 1JRRA 1SEKA 1UHGA 2BEHL 2WY0C 3EVJI 1EZXA 2XN5A 2WXZA 1XQGA 4ZK0A 3F02A 1ANTI 4AU3A 4ZK3A 8APIA 1DVMA 5CDZA 1OVAB 1QMNA 3NE4A 1LK6I 1OVAC 3LE2A 3NDAA 2B5TI 2RIVA 1A7CA 1HLEA 4GA7A 1E05I 4ROBA 5INWA 4YIAA 4KDSA 4ROAA 1TB6I 4AQHA 2OAYA 5IO1A 4RSQA 1OO8A 5EI0A 2XN3A 1ATUA 1JMOA 2OL2A 2WY1A 1R1LI 1YXAA 2HI9A 3EOXA 3FGQA 5HGCA 1M93B 1OPHA 3Q03A 4AFXA 2H4PA 1LQ8A 3R4LA 4AJUA 1SNGA 1OVAA 2GD4C 5C98A 4DY0A 1PSIA 4P0FA 1XU8A 5BRRI 3LW2A
chains in the Genus database with same CATH topology
2B4XI 1LJ5A 2ANTI 3T1PA 2D26A 2XN6A 2B4XL 4EB1L 2WXXA 2H4QA 2ARQA 4C49A 1OC0A 1ATTA 1DZHL 1SR5A 3VVJA 3ZHAA 3STOA 5CDXA 1JVQI 1DZGL 1XQJA 4IC0A 3DLWA 9APIA 1DVNA 1E04I 2PEFA 1C5GA 2WXWA 4AU4A 3PB1I 1D5SA 2DUTA 1BR8I 3DRMA 4AU2A 1IMVA 2ARRA 1JMJA 2PEEA 1T1FA 4C41A 4DY7C 1E03I 4AJTA 4R9IA 2VDXA 3CWLA 4RO9A 1AS4A 1F0CA 3CWMA 1OYHI 2VDYA 2R9YA 3F5NA 4CAAA 4Y3KA 4EB1I 5CE0A 1WZ9A 2ZV6A 3H5CA 4G8OA 1QMBA 2RIWA 1OYHL 1DB2A 4X30A 9PAIA 1DZHI 1QLPA 3PZFA 2HIJI 2QUGA 3OZQA 1DZGI 2CEOA 2HIJL 3UT3A 2ACHA 2WXZC 1AZXI 1C8OA 4AU3B 2V95A 3NDDA 1JTIA 3B9FI 3NDFA 1IZ2A 1BY7A 1ATHA 1MTPA 2H4RA 3DY0A 3Q02A 3F1SA 1K9OI 7APIA 1B3KA 4IF8A 4PYWA 2WXYC 3DRUA 1JJOC 3KCGI 2XN7A 4BB2A 2VH4A 2ZNHA 3CVMA 1HP7A 4P0OA 4DTEA 4G8RA 1NQ9I 4Y40A 1KCTA 2BEHI 3CAAA 1JRRA 1SEKA 1UHGA 2BEHL 2WY0C 3EVJI 1EZXA 2XN5A 2WXZA 1XQGA 4ZK0A 3F02A 1ANTI 4AU3A 4ZK3A 8APIA 1DVMA 5CDZA 1OVAB 1QMNA 3NE4A 1LK6I 1OVAC 3LE2A 3NDAA 2B5TI 2RIVA 1A7CA 1HLEA 4GA7A 1E05I 4ROBA 5INWA 4YIAA 4KDSA 4ROAA 1TB6I 4AQHA 2OAYA 5IO1A 4RSQA 1OO8A 5EI0A 2XN3A 1ATUA 1JMOA 2OL2A 2WY1A 1R1LI 1YXAA 2HI9A 3EOXA 3FGQA 5HGCA 1M93B 1OPHA 3Q03A 4AFXA 2H4PA 1LQ8A 3R4LA 4AJUA 1SNGA 1OVAA 2GD4C 5C98A 4DY0A 1PSIA 4P0FA 1XU8A 5BRRI 3LW2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B4X I;  1LJ5 A;  2ANT I;  3T1P A;  2D26 A;  2XN6 A;  2B4X L;  4EB1 L;  2WXX A;  2H4Q A;  2ARQ A;  4C49 A;  1OC0 A;  1ATT A;  1DZH L;  1SR5 A;  3VVJ A;  3ZHA A;  3STO A;  5CDX A;  1JVQ I;  1DZG L;  1XQJ A;  4IC0 A;  3DLW A;  9API A;  1DVN A;  1E04 I;  2PEF A;  1C5G A;  2WXW A;  4AU4 A;  3PB1 I;  1D5S A;  2DUT A;  1BR8 I;  3DRM A;  4AU2 A;  1IMV A;  2ARR A;  1JMJ A;  2PEE A;  1T1F A;  4C41 A;  4DY7 C;  1E03 I;  4AJT A;  4R9I A;  2VDX A;  3CWL A;  4RO9 A;  1AS4 A;  1F0C A;  3CWM A;  1OYH I;  2VDY A;  2R9Y A;  3F5N A;  4CAA A;  4Y3K A;  4EB1 I;  5CE0 A;  1WZ9 A;  2ZV6 A;  3H5C A;  4G8O A;  1QMB A;  2RIW A;  1OYH L;  1DB2 A;  4X30 A;  9PAI A;  1DZH I;  1QLP A;  3PZF A;  2HIJ I;  2QUG A;  3OZQ A;  1DZG I;  2CEO A;  2HIJ L;  3UT3 A;  2ACH A;  2WXZ C;  1AZX I;  1C8O A;  4AU3 B;  2V95 A;  3NDD A;  1JTI A;  3B9F I;  3NDF A;  1IZ2 A;  1BY7 A;  1ATH A;  1MTP A;  2H4R A;  3DY0 A;  3Q02 A;  3F1S A;  1K9O I;  7API A;  1B3K A;  4IF8 A;  4PYW A;  2WXY C;  3DRU A;  1JJO C;  3KCG I;  2XN7 A;  4BB2 A;  2VH4 A;  2ZNH A;  3CVM A;  1HP7 A;  4P0O A;  4DTE A;  4G8R A;  1NQ9 I;  4Y40 A;  1KCT A;  2BEH I;  3CAA A;  1JRR A;  1SEK A;  1UHG A;  2BEH L;  2WY0 C;  3EVJ I;  1EZX A;  2XN5 A;  2WXZ A;  1XQG A;  4ZK0 A;  3F02 A;  1ANT I;  4AU3 A;  4ZK3 A;  8API A;  1DVM A;  5CDZ A;  1OVA B;  1QMN A;  3NE4 A;  1LK6 I;  1OVA C;  3LE2 A;  3NDA A;  2B5T I;  2RIV A;  1A7C A;  1HLE A;  4GA7 A;  1E05 I;  4ROB A;  5INW A;  4YIA A;  4KDS A;  4ROA A;  1TB6 I;  4AQH A;  2OAY A;  5IO1 A;  4RSQ A;  1OO8 A;  5EI0 A;  2XN3 A;  1ATU A;  1JMO A;  2OL2 A;  2WY1 A;  1R1L I;  1YXA A;  2HI9 A;  3EOX A;  3FGQ A;  5HGC A;  1M93 B;  1OPH A;  3Q03 A;  4AFX A;  2H4P A;  1LQ8 A;  3R4L A;  4AJU A;  1SNG A;  1OVA A;  2GD4 C;  5C98 A;  4DY0 A;  1PSI A;  4P0F A;  1XU8 A;  5BRR I;  3LW2 A; 
#chains in the Genus database with same CATH topology
 2B4X I;  1LJ5 A;  2ANT I;  3T1P A;  2D26 A;  2XN6 A;  2B4X L;  4EB1 L;  2WXX A;  2H4Q A;  2ARQ A;  4C49 A;  1OC0 A;  1ATT A;  1DZH L;  1SR5 A;  3VVJ A;  3ZHA A;  3STO A;  5CDX A;  1JVQ I;  1DZG L;  1XQJ A;  4IC0 A;  3DLW A;  9API A;  1DVN A;  1E04 I;  2PEF A;  1C5G A;  2WXW A;  4AU4 A;  3PB1 I;  1D5S A;  2DUT A;  1BR8 I;  3DRM A;  4AU2 A;  1IMV A;  2ARR A;  1JMJ A;  2PEE A;  1T1F A;  4C41 A;  4DY7 C;  1E03 I;  4AJT A;  4R9I A;  2VDX A;  3CWL A;  4RO9 A;  1AS4 A;  1F0C A;  3CWM A;  1OYH I;  2VDY A;  2R9Y A;  3F5N A;  4CAA A;  4Y3K A;  4EB1 I;  5CE0 A;  1WZ9 A;  2ZV6 A;  3H5C A;  4G8O A;  1QMB A;  2RIW A;  1OYH L;  1DB2 A;  4X30 A;  9PAI A;  1DZH I;  1QLP A;  3PZF A;  2HIJ I;  2QUG A;  3OZQ A;  1DZG I;  2CEO A;  2HIJ L;  3UT3 A;  2ACH A;  2WXZ C;  1AZX I;  1C8O A;  4AU3 B;  2V95 A;  3NDD A;  1JTI A;  3B9F I;  3NDF A;  1IZ2 A;  1BY7 A;  1ATH A;  1MTP A;  2H4R A;  3DY0 A;  3Q02 A;  3F1S A;  1K9O I;  7API A;  1B3K A;  4IF8 A;  4PYW A;  2WXY C;  3DRU A;  1JJO C;  3KCG I;  2XN7 A;  4BB2 A;  2VH4 A;  2ZNH A;  3CVM A;  1HP7 A;  4P0O A;  4DTE A;  4G8R A;  1NQ9 I;  4Y40 A;  1KCT A;  2BEH I;  3CAA A;  1JRR A;  1SEK A;  1UHG A;  2BEH L;  2WY0 C;  3EVJ I;  1EZX A;  2XN5 A;  2WXZ A;  1XQG A;  4ZK0 A;  3F02 A;  1ANT I;  4AU3 A;  4ZK3 A;  8API A;  1DVM A;  5CDZ A;  1OVA B;  1QMN A;  3NE4 A;  1LK6 I;  1OVA C;  3LE2 A;  3NDA A;  2B5T I;  2RIV A;  1A7C A;  1HLE A;  4GA7 A;  1E05 I;  4ROB A;  5INW A;  4YIA A;  4KDS A;  4ROA A;  1TB6 I;  4AQH A;  2OAY A;  5IO1 A;  4RSQ A;  1OO8 A;  5EI0 A;  2XN3 A;  1ATU A;  1JMO A;  2OL2 A;  2WY1 A;  1R1L I;  1YXA A;  2HI9 A;  3EOX A;  3FGQ A;  5HGC A;  1M93 B;  1OPH A;  3Q03 A;  4AFX A;  2H4P A;  1LQ8 A;  3R4L A;  4AJU A;  1SNG A;  1OVA A;  2GD4 C;  5C98 A;  4DY0 A;  1PSI A;  4P0F A;  1XU8 A;  5BRR I;  3LW2 A; 
#chains in the Genus database with same CATH homology
 2B4X I;  1LJ5 A;  2ANT I;  3T1P A;  2D26 A;  2XN6 A;  2B4X L;  4EB1 L;  2WXX A;  2H4Q A;  2ARQ A;  4C49 A;  1OC0 A;  1ATT A;  1DZH L;  1SR5 A;  3VVJ A;  3ZHA A;  3STO A;  5CDX A;  1JVQ I;  1DZG L;  1XQJ A;  4IC0 A;  3DLW A;  9API A;  1DVN A;  1E04 I;  2PEF A;  1C5G A;  2WXW A;  4AU4 A;  3PB1 I;  1D5S A;  2DUT A;  1BR8 I;  3DRM A;  4AU2 A;  1IMV A;  2ARR A;  1JMJ A;  2PEE A;  1T1F A;  4C41 A;  4DY7 C;  1E03 I;  4AJT A;  4R9I A;  2VDX A;  3CWL A;  4RO9 A;  1AS4 A;  1F0C A;  3CWM A;  1OYH I;  2VDY A;  2R9Y A;  3F5N A;  4CAA A;  4Y3K A;  4EB1 I;  5CE0 A;  1WZ9 A;  2ZV6 A;  3H5C A;  4G8O A;  1QMB A;  2RIW A;  1OYH L;  1DB2 A;  4X30 A;  9PAI A;  1DZH I;  1QLP A;  3PZF A;  2HIJ I;  2QUG A;  3OZQ A;  1DZG I;  2CEO A;  2HIJ L;  3UT3 A;  2ACH A;  2WXZ C;  1AZX I;  1C8O A;  4AU3 B;  2V95 A;  3NDD A;  1JTI A;  3B9F I;  3NDF A;  1IZ2 A;  1BY7 A;  1ATH A;  1MTP A;  2H4R A;  3DY0 A;  3Q02 A;  3F1S A;  1K9O I;  7API A;  1B3K A;  4IF8 A;  4PYW A;  2WXY C;  3DRU A;  1JJO C;  3KCG I;  2XN7 A;  4BB2 A;  2VH4 A;  2ZNH A;  3CVM A;  1HP7 A;  4P0O A;  4DTE A;  4G8R A;  1NQ9 I;  4Y40 A;  1KCT A;  2BEH I;  3CAA A;  1JRR A;  1SEK A;  1UHG A;  2BEH L;  2WY0 C;  3EVJ I;  1EZX A;  2XN5 A;  2WXZ A;  1XQG A;  4ZK0 A;  3F02 A;  1ANT I;  4AU3 A;  4ZK3 A;  8API A;  1DVM A;  5CDZ A;  1OVA B;  1QMN A;  3NE4 A;  1LK6 I;  1OVA C;  3LE2 A;  3NDA A;  2B5T I;  2RIV A;  1A7C A;  1HLE A;  4GA7 A;  1E05 I;  4ROB A;  5INW A;  4YIA A;  4KDS A;  4ROA A;  1TB6 I;  4AQH A;  2OAY A;  5IO1 A;  4RSQ A;  1OO8 A;  5EI0 A;  2XN3 A;  1ATU A;  1JMO A;  2OL2 A;  2WY1 A;  1R1L I;  1YXA A;  2HI9 A;  3EOX A;  3FGQ A;  5HGC A;  1M93 B;  1OPH A;  3Q03 A;  4AFX A;  2H4P A;  1LQ8 A;  3R4L A;  4AJU A;  1SNG A;  1OVA A;  2GD4 C;  5C98 A;  4DY0 A;  1PSI A;  4P0F A;  1XU8 A;  5BRR I;  3LW2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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