3CAAA

Cleaved antichymotrypsin a347r
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
334
structure length
334
Chain Sequence
ASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTERSAATAVKITLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
pubmed doi rcsb
molecule keywords ANTICHYMOTRYPSIN
molecule tags Serpin
source organism Homo sapiens
total genus 92
structure length 334
sequence length 334
ec nomenclature
pdb deposition date 1997-08-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3caaA01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3caaA02
2BEHI 1OVAA 3EOXA 4P0OA 4RSQA 2XN7A 3DRMA 2H4RA 3DLWA 4GA7A 4RO9A 4C41A 2D26A 1DB2A 4P0FA 8APIA 1BY7A 2B5TI 4AU3A 3B9FI 3NDAA 3LE2A 4PYWA 5CDZA 3F02A 4IC0A 5BRRI 1A7CA 1ANTI 4IF8A 4R9IA 2PEEA 1EZXA 3CVMA 1ATTA 2OL2A 3DY0A 1WZ9A 4ZK0A 2WXWA 2RIWA 1MTPA 1SR5A 2WY1A 1AZXI 1QLPA 3OZQA 1K9OI 2XN3A 1B3KA 3FGQA 3STOA 2XN6A 2R9YA 1LK6I 3H5CA 1E03I 1BR8I 4Y40A 5INWA 9APIA 4AFXA 3PZFA 1DZHL 3DRUA 1JMJA 1HP7A 4EB1I 2CEOA 2H4QA 2H4PA 2ARQA 1DZHI 4G8RA 4DTEA 5CDXA 1JJOC 4ZK3A 1E05I 1TB6I 1AS4A 2B4XL 3Q02A 4Y3KA 3VVJA 2WXZA 4ROAA 2GD4C 2B4XI 4G8OA 1T1FA 9PAIA 1C5GA 1HLEA 1XQJA 4KDSA 2HIJL 1OC0A 2VH4A 1IMVA 1OVAC 2VDYA 4AQHA 1OO8A 3KCGI 1XQGA 3CWLA 2HIJI 3R4LA 2ACHA 1PSIA 2PEFA 2ARRA 2WXYC 1UHGA 2ZV6A 4C49A 7APIA 1OYHL 1LQ8A 2WY0C 3CAAA 1DVMA 3F5NA 2XN5A 1D5SA 3NDFA 1C8OA 1JTIA 1OYHI 3F1SA 1NQ9I 2VDXA 5IO1A 1QMNA 1E04I 2WXZC 4YIAA 2DUTA 3EVJI 4DY7C 5C98A 1ATHA 1XU8A 1IZ2A 1M93B 1ATUA 1JVQI 1DZGL 3NE4A 1LJ5A 4AU3B 1SNGA 2ZNHA 4AU4A 2V95A 1OPHA 1DVNA 1F0CA 2ANTI 3UT3A 1DZGI 5HGCA 4AU2A 5CE0A 4CAAA 2QUGA 1R1LI 3Q03A 3PB1I 4ROBA 1JRRA 2WXXA 3CWMA 2OAYA 1JMOA 3ZHAA 4DY0A 1KCTA 3NDDA 2HI9A 2RIVA 3LW2A 4EB1L 1YXAA 1QMBA 3T1PA 1OVAB 2BEHL 4AJTA 5EI0A 1SEKA 4BB2A 4X30A 4AJUA
chains in the Genus database with same CATH superfamily
2BEHI 1OVAA 3EOXA 4P0OA 4RSQA 2XN7A 3DRMA 2H4RA 3DLWA 4GA7A 4RO9A 4C41A 2D26A 1DB2A 4P0FA 8APIA 1BY7A 2B5TI 4AU3A 3B9FI 3NDAA 3LE2A 4PYWA 5CDZA 3F02A 4IC0A 5BRRI 1A7CA 1ANTI 4IF8A 4R9IA 2PEEA 1EZXA 3CVMA 1ATTA 2OL2A 3DY0A 1WZ9A 4ZK0A 2WXWA 2RIWA 1MTPA 1SR5A 2WY1A 1AZXI 1QLPA 3OZQA 1K9OI 2XN3A 1B3KA 3FGQA 3STOA 2XN6A 2R9YA 1LK6I 3H5CA 1E03I 1BR8I 4Y40A 5INWA 9APIA 4AFXA 3PZFA 1DZHL 3DRUA 1JMJA 1HP7A 4EB1I 2CEOA 2H4QA 2H4PA 2ARQA 1DZHI 4G8RA 4DTEA 5CDXA 1JJOC 4ZK3A 1E05I 1TB6I 1AS4A 2B4XL 3Q02A 4Y3KA 3VVJA 2WXZA 4ROAA 2GD4C 2B4XI 4G8OA 1T1FA 9PAIA 1C5GA 1HLEA 1XQJA 4KDSA 2HIJL 1OC0A 2VH4A 1IMVA 1OVAC 2VDYA 4AQHA 1OO8A 3KCGI 1XQGA 3CWLA 2HIJI 3R4LA 2ACHA 1PSIA 2PEFA 2ARRA 2WXYC 1UHGA 2ZV6A 4C49A 7APIA 1OYHL 1LQ8A 2WY0C 3CAAA 1DVMA 3F5NA 2XN5A 1D5SA 3NDFA 1C8OA 1JTIA 1OYHI 3F1SA 1NQ9I 2VDXA 5IO1A 1QMNA 1E04I 2WXZC 4YIAA 2DUTA 3EVJI 4DY7C 5C98A 1ATHA 1XU8A 1IZ2A 1M93B 1ATUA 1JVQI 1DZGL 3NE4A 1LJ5A 4AU3B 1SNGA 2ZNHA 4AU4A 2V95A 1OPHA 1DVNA 1F0CA 2ANTI 3UT3A 1DZGI 5HGCA 4AU2A 5CE0A 4CAAA 2QUGA 1R1LI 3Q03A 3PB1I 4ROBA 1JRRA 2WXXA 3CWMA 2OAYA 1JMOA 3ZHAA 4DY0A 1KCTA 3NDDA 2HI9A 2RIVA 3LW2A 4EB1L 1YXAA 1QMBA 3T1PA 1OVAB 2BEHL 4AJTA 5EI0A 1SEKA 4BB2A 4X30A 4AJUA
chains in the Genus database with same CATH topology
2BEHI 1OVAA 3EOXA 4P0OA 4RSQA 2XN7A 3DRMA 2H4RA 3DLWA 4GA7A 4RO9A 4C41A 2D26A 1DB2A 4P0FA 8APIA 1BY7A 2B5TI 4AU3A 3B9FI 3NDAA 3LE2A 4PYWA 5CDZA 3F02A 4IC0A 5BRRI 1A7CA 1ANTI 4IF8A 4R9IA 2PEEA 1EZXA 3CVMA 1ATTA 2OL2A 3DY0A 1WZ9A 4ZK0A 2WXWA 2RIWA 1MTPA 1SR5A 2WY1A 1AZXI 1QLPA 3OZQA 1K9OI 2XN3A 1B3KA 3FGQA 3STOA 2XN6A 2R9YA 1LK6I 3H5CA 1E03I 1BR8I 4Y40A 5INWA 9APIA 4AFXA 3PZFA 1DZHL 3DRUA 1JMJA 1HP7A 4EB1I 2CEOA 2H4QA 2H4PA 2ARQA 1DZHI 4G8RA 4DTEA 5CDXA 1JJOC 4ZK3A 1E05I 1TB6I 1AS4A 2B4XL 3Q02A 4Y3KA 3VVJA 2WXZA 4ROAA 2GD4C 2B4XI 4G8OA 1T1FA 9PAIA 1C5GA 1HLEA 1XQJA 4KDSA 2HIJL 1OC0A 2VH4A 1IMVA 1OVAC 2VDYA 4AQHA 1OO8A 3KCGI 1XQGA 3CWLA 2HIJI 3R4LA 2ACHA 1PSIA 2PEFA 2ARRA 2WXYC 1UHGA 2ZV6A 4C49A 7APIA 1OYHL 1LQ8A 2WY0C 3CAAA 1DVMA 3F5NA 2XN5A 1D5SA 3NDFA 1C8OA 1JTIA 1OYHI 3F1SA 1NQ9I 2VDXA 5IO1A 1QMNA 1E04I 2WXZC 4YIAA 2DUTA 3EVJI 4DY7C 5C98A 1ATHA 1XU8A 1IZ2A 1M93B 1ATUA 1JVQI 1DZGL 3NE4A 1LJ5A 4AU3B 1SNGA 2ZNHA 4AU4A 2V95A 1OPHA 1DVNA 1F0CA 2ANTI 3UT3A 1DZGI 5HGCA 4AU2A 5CE0A 4CAAA 2QUGA 1R1LI 3Q03A 3PB1I 4ROBA 1JRRA 2WXXA 3CWMA 2OAYA 1JMOA 3ZHAA 4DY0A 1KCTA 3NDDA 2HI9A 2RIVA 3LW2A 4EB1L 1YXAA 1QMBA 3T1PA 1OVAB 2BEHL 4AJTA 5EI0A 1SEKA 4BB2A 4X30A 4AJUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BEH I;  1OVA A;  3EOX A;  4P0O A;  4RSQ A;  2XN7 A;  3DRM A;  2H4R A;  3DLW A;  4GA7 A;  4RO9 A;  4C41 A;  2D26 A;  1DB2 A;  4P0F A;  8API A;  1BY7 A;  2B5T I;  4AU3 A;  3B9F I;  3NDA A;  3LE2 A;  4PYW A;  5CDZ A;  3F02 A;  4IC0 A;  5BRR I;  1A7C A;  1ANT I;  4IF8 A;  4R9I A;  2PEE A;  1EZX A;  3CVM A;  1ATT A;  2OL2 A;  3DY0 A;  1WZ9 A;  4ZK0 A;  2WXW A;  2RIW A;  1MTP A;  1SR5 A;  2WY1 A;  1AZX I;  1QLP A;  3OZQ A;  1K9O I;  2XN3 A;  1B3K A;  3FGQ A;  3STO A;  2XN6 A;  2R9Y A;  1LK6 I;  3H5C A;  1E03 I;  1BR8 I;  4Y40 A;  5INW A;  9API A;  4AFX A;  3PZF A;  1DZH L;  3DRU A;  1JMJ A;  1HP7 A;  4EB1 I;  2CEO A;  2H4Q A;  2H4P A;  2ARQ A;  1DZH I;  4G8R A;  4DTE A;  5CDX A;  1JJO C;  4ZK3 A;  1E05 I;  1TB6 I;  1AS4 A;  2B4X L;  3Q02 A;  4Y3K A;  3VVJ A;  2WXZ A;  4ROA A;  2GD4 C;  2B4X I;  4G8O A;  1T1F A;  9PAI A;  1C5G A;  1HLE A;  1XQJ A;  4KDS A;  2HIJ L;  1OC0 A;  2VH4 A;  1IMV A;  1OVA C;  2VDY A;  4AQH A;  1OO8 A;  3KCG I;  1XQG A;  3CWL A;  2HIJ I;  3R4L A;  2ACH A;  1PSI A;  2PEF A;  2ARR A;  2WXY C;  1UHG A;  2ZV6 A;  4C49 A;  7API A;  1OYH L;  1LQ8 A;  2WY0 C;  3CAA A;  1DVM A;  3F5N A;  2XN5 A;  1D5S A;  3NDF A;  1C8O A;  1JTI A;  1OYH I;  3F1S A;  1NQ9 I;  2VDX A;  5IO1 A;  1QMN A;  1E04 I;  2WXZ C;  4YIA A;  2DUT A;  3EVJ I;  4DY7 C;  5C98 A;  1ATH A;  1XU8 A;  1IZ2 A;  1M93 B;  1ATU A;  1JVQ I;  1DZG L;  3NE4 A;  1LJ5 A;  4AU3 B;  1SNG A;  2ZNH A;  4AU4 A;  2V95 A;  1OPH A;  1DVN A;  1F0C A;  2ANT I;  3UT3 A;  1DZG I;  5HGC A;  4AU2 A;  5CE0 A;  4CAA A;  2QUG A;  1R1L I;  3Q03 A;  3PB1 I;  4ROB A;  1JRR A;  2WXX A;  3CWM A;  2OAY A;  1JMO A;  3ZHA A;  4DY0 A;  1KCT A;  3NDD A;  2HI9 A;  2RIV A;  3LW2 A;  4EB1 L;  1YXA A;  1QMB A;  3T1P A;  1OVA B;  2BEH L;  4AJT A;  5EI0 A;  1SEK A;  4BB2 A;  4X30 A;  4AJU A; 
#chains in the Genus database with same CATH topology
 2BEH I;  1OVA A;  3EOX A;  4P0O A;  4RSQ A;  2XN7 A;  3DRM A;  2H4R A;  3DLW A;  4GA7 A;  4RO9 A;  4C41 A;  2D26 A;  1DB2 A;  4P0F A;  8API A;  1BY7 A;  2B5T I;  4AU3 A;  3B9F I;  3NDA A;  3LE2 A;  4PYW A;  5CDZ A;  3F02 A;  4IC0 A;  5BRR I;  1A7C A;  1ANT I;  4IF8 A;  4R9I A;  2PEE A;  1EZX A;  3CVM A;  1ATT A;  2OL2 A;  3DY0 A;  1WZ9 A;  4ZK0 A;  2WXW A;  2RIW A;  1MTP A;  1SR5 A;  2WY1 A;  1AZX I;  1QLP A;  3OZQ A;  1K9O I;  2XN3 A;  1B3K A;  3FGQ A;  3STO A;  2XN6 A;  2R9Y A;  1LK6 I;  3H5C A;  1E03 I;  1BR8 I;  4Y40 A;  5INW A;  9API A;  4AFX A;  3PZF A;  1DZH L;  3DRU A;  1JMJ A;  1HP7 A;  4EB1 I;  2CEO A;  2H4Q A;  2H4P A;  2ARQ A;  1DZH I;  4G8R A;  4DTE A;  5CDX A;  1JJO C;  4ZK3 A;  1E05 I;  1TB6 I;  1AS4 A;  2B4X L;  3Q02 A;  4Y3K A;  3VVJ A;  2WXZ A;  4ROA A;  2GD4 C;  2B4X I;  4G8O A;  1T1F A;  9PAI A;  1C5G A;  1HLE A;  1XQJ A;  4KDS A;  2HIJ L;  1OC0 A;  2VH4 A;  1IMV A;  1OVA C;  2VDY A;  4AQH A;  1OO8 A;  3KCG I;  1XQG A;  3CWL A;  2HIJ I;  3R4L A;  2ACH A;  1PSI A;  2PEF A;  2ARR A;  2WXY C;  1UHG A;  2ZV6 A;  4C49 A;  7API A;  1OYH L;  1LQ8 A;  2WY0 C;  3CAA A;  1DVM A;  3F5N A;  2XN5 A;  1D5S A;  3NDF A;  1C8O A;  1JTI A;  1OYH I;  3F1S A;  1NQ9 I;  2VDX A;  5IO1 A;  1QMN A;  1E04 I;  2WXZ C;  4YIA A;  2DUT A;  3EVJ I;  4DY7 C;  5C98 A;  1ATH A;  1XU8 A;  1IZ2 A;  1M93 B;  1ATU A;  1JVQ I;  1DZG L;  3NE4 A;  1LJ5 A;  4AU3 B;  1SNG A;  2ZNH A;  4AU4 A;  2V95 A;  1OPH A;  1DVN A;  1F0C A;  2ANT I;  3UT3 A;  1DZG I;  5HGC A;  4AU2 A;  5CE0 A;  4CAA A;  2QUG A;  1R1L I;  3Q03 A;  3PB1 I;  4ROB A;  1JRR A;  2WXX A;  3CWM A;  2OAY A;  1JMO A;  3ZHA A;  4DY0 A;  1KCT A;  3NDD A;  2HI9 A;  2RIV A;  3LW2 A;  4EB1 L;  1YXA A;  1QMB A;  3T1P A;  1OVA B;  2BEH L;  4AJT A;  5EI0 A;  1SEK A;  4BB2 A;  4X30 A;  4AJU A; 
#chains in the Genus database with same CATH homology
 2BEH I;  1OVA A;  3EOX A;  4P0O A;  4RSQ A;  2XN7 A;  3DRM A;  2H4R A;  3DLW A;  4GA7 A;  4RO9 A;  4C41 A;  2D26 A;  1DB2 A;  4P0F A;  8API A;  1BY7 A;  2B5T I;  4AU3 A;  3B9F I;  3NDA A;  3LE2 A;  4PYW A;  5CDZ A;  3F02 A;  4IC0 A;  5BRR I;  1A7C A;  1ANT I;  4IF8 A;  4R9I A;  2PEE A;  1EZX A;  3CVM A;  1ATT A;  2OL2 A;  3DY0 A;  1WZ9 A;  4ZK0 A;  2WXW A;  2RIW A;  1MTP A;  1SR5 A;  2WY1 A;  1AZX I;  1QLP A;  3OZQ A;  1K9O I;  2XN3 A;  1B3K A;  3FGQ A;  3STO A;  2XN6 A;  2R9Y A;  1LK6 I;  3H5C A;  1E03 I;  1BR8 I;  4Y40 A;  5INW A;  9API A;  4AFX A;  3PZF A;  1DZH L;  3DRU A;  1JMJ A;  1HP7 A;  4EB1 I;  2CEO A;  2H4Q A;  2H4P A;  2ARQ A;  1DZH I;  4G8R A;  4DTE A;  5CDX A;  1JJO C;  4ZK3 A;  1E05 I;  1TB6 I;  1AS4 A;  2B4X L;  3Q02 A;  4Y3K A;  3VVJ A;  2WXZ A;  4ROA A;  2GD4 C;  2B4X I;  4G8O A;  1T1F A;  9PAI A;  1C5G A;  1HLE A;  1XQJ A;  4KDS A;  2HIJ L;  1OC0 A;  2VH4 A;  1IMV A;  1OVA C;  2VDY A;  4AQH A;  1OO8 A;  3KCG I;  1XQG A;  3CWL A;  2HIJ I;  3R4L A;  2ACH A;  1PSI A;  2PEF A;  2ARR A;  2WXY C;  1UHG A;  2ZV6 A;  4C49 A;  7API A;  1OYH L;  1LQ8 A;  2WY0 C;  3CAA A;  1DVM A;  3F5N A;  2XN5 A;  1D5S A;  3NDF A;  1C8O A;  1JTI A;  1OYH I;  3F1S A;  1NQ9 I;  2VDX A;  5IO1 A;  1QMN A;  1E04 I;  2WXZ C;  4YIA A;  2DUT A;  3EVJ I;  4DY7 C;  5C98 A;  1ATH A;  1XU8 A;  1IZ2 A;  1M93 B;  1ATU A;  1JVQ I;  1DZG L;  3NE4 A;  1LJ5 A;  4AU3 B;  1SNG A;  2ZNH A;  4AU4 A;  2V95 A;  1OPH A;  1DVN A;  1F0C A;  2ANT I;  3UT3 A;  1DZG I;  5HGC A;  4AU2 A;  5CE0 A;  4CAA A;  2QUG A;  1R1L I;  3Q03 A;  3PB1 I;  4ROB A;  1JRR A;  2WXX A;  3CWM A;  2OAY A;  1JMO A;  3ZHA A;  4DY0 A;  1KCT A;  3NDD A;  2HI9 A;  2RIV A;  3LW2 A;  4EB1 L;  1YXA A;  1QMB A;  3T1P A;  1OVA B;  2BEH L;  4AJT A;  5EI0 A;  1SEK A;  4BB2 A;  4X30 A;  4AJU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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