3EOXA

High quality structure of cleaved pai-1-stab
Total Genus 113
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
379
structure length
370
Chain Sequence
VHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFTVKQVDFSEVERARFIINDWVKTHTKGMISHLLGTGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRPFQADFTSLSDQEPLHVALALQKVKIEVNESGTVASSSTAVIVEIIIDRPFLFVVRHNPTGTVLFMGQVMEP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High quality structure of cleaved PAI-1-stab.
pubmed doi rcsb
molecule keywords Plasminogen activator inhibitor 1
molecule tags Blood clotting
source organism Homo sapiens
total genus 113
structure length 370
sequence length 379
ec nomenclature
pdb deposition date 2008-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3eoxA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3eoxA01
2HIJL 2VH4A 3DY0A 2H4PA 3Q02A 1UHGA 1QMNA 1XQJA 1BY7A 2BEHI 1YXAA 2WXWA 9PAIA 5CDZA 1WZ9A 3PZFA 1C8OA 3NDAA 3PB1I 4EB1L 3DLWA 1DZGL 2V95A 3NE4A 2WXXA 1D5SA 5BRRI 1T1FA 1ATTA 4AU2A 3DRUA 4ZK0A 1IMVA 5HGCA 2R9YA 1JMJA 2B4XL 3Q03A 4RO9A 4DTEA 3CVMA 4Y40A 4DY0A 2QUGA 1C5GA 1OVAC 1K9OI 3NDDA 1HP7A 4DY7C 2OAYA 3OZQA 1XQGA 4G8RA 4AJTA 3STOA 1ATUA 1BR8I 2B5TI 1XU8A 1TB6I 3FGQA 2GD4C 3EOXA 2VDXA 2PEEA 4AQHA 5EI0A 2XN6A 4YIAA 1HLEA 8APIA 4AFXA 1EZXA 1DZHI 1DVNA 1PSIA 3F1SA 2XN5A 2CEOA 4AU3B 1LK6I 3F02A 2ARQA 4KDSA 1LJ5A 3CWLA 1AS4A 1OYHI 4X30A 4AU3A 3CWMA 3DRMA 2WY1A 2RIWA 2XN7A 4RSQA 2RIVA 3R4LA 1KCTA 2WXZA 4C49A 1SNGA 1QLPA 3F5NA 4ZK3A 1JMOA 2HIJI 3LW2A 1E05I 4P0FA 1JRRA 4CAAA 2BEHL 1QMBA 1ANTI 1OVAB 9APIA 2XN3A 1OC0A 1OVAA 2DUTA 5CDXA 1E04I 2HI9A 2H4RA 1LQ8A 2ARRA 4EB1I 1DZGI 1NQ9I 2ZNHA 1E03I 1OYHL 4AU4A 1ATHA 3CAAA 1A7CA 5CE0A 4GA7A 2WY0C 4ROAA 3KCGI 2VDYA 1M93B 1DVMA 1R1LI 4P0OA 1B3KA 3LE2A 1AZXI 3ZHAA 3EVJI 2PEFA 4R9IA 5INWA 2D26A 2WXYC 5C98A 3T1PA 1SEKA 3H5CA 2ZV6A 1F0CA 2H4QA 4PYWA 4BB2A 1DB2A 1DZHL 1JJOC 1OPHA 3B9FI 3VVJA 2ACHA 2WXZC 2OL2A 7APIA 1MTPA 4C41A 1JTIA 4G8OA 4Y3KA 3UT3A 3NDFA 1OO8A 2B4XI 4ROBA 4AJUA 1IZ2A 1JVQI 2ANTI 4IF8A 5IO1A 4IC0A 1SR5A
chains in the Genus database with same CATH superfamily
2HIJL 2VH4A 3DY0A 2H4PA 3Q02A 1UHGA 1QMNA 1XQJA 1BY7A 2BEHI 1YXAA 2WXWA 9PAIA 5CDZA 1WZ9A 3PZFA 1C8OA 3NDAA 3PB1I 4EB1L 3DLWA 1DZGL 2V95A 3NE4A 2WXXA 1D5SA 5BRRI 1T1FA 1ATTA 4AU2A 3DRUA 4ZK0A 1IMVA 5HGCA 2R9YA 1JMJA 2B4XL 3Q03A 4RO9A 4DTEA 3CVMA 4Y40A 4DY0A 2QUGA 1C5GA 1OVAC 1K9OI 3NDDA 1HP7A 4DY7C 2OAYA 3OZQA 1XQGA 4G8RA 4AJTA 3STOA 1ATUA 1BR8I 2B5TI 1XU8A 1TB6I 3FGQA 2GD4C 3EOXA 2VDXA 2PEEA 4AQHA 5EI0A 2XN6A 4YIAA 1HLEA 8APIA 4AFXA 1EZXA 1DZHI 1DVNA 1PSIA 3F1SA 2XN5A 2CEOA 4AU3B 1LK6I 3F02A 2ARQA 4KDSA 1LJ5A 3CWLA 1AS4A 1OYHI 4X30A 4AU3A 3CWMA 3DRMA 2WY1A 2RIWA 2XN7A 4RSQA 2RIVA 3R4LA 1KCTA 2WXZA 4C49A 1SNGA 1QLPA 3F5NA 4ZK3A 1JMOA 2HIJI 3LW2A 1E05I 4P0FA 1JRRA 4CAAA 2BEHL 1QMBA 1ANTI 1OVAB 9APIA 2XN3A 1OC0A 1OVAA 2DUTA 5CDXA 1E04I 2HI9A 2H4RA 1LQ8A 2ARRA 4EB1I 1DZGI 1NQ9I 2ZNHA 1E03I 1OYHL 4AU4A 1ATHA 3CAAA 1A7CA 5CE0A 4GA7A 2WY0C 4ROAA 3KCGI 2VDYA 1M93B 1DVMA 1R1LI 4P0OA 1B3KA 3LE2A 1AZXI 3ZHAA 3EVJI 2PEFA 4R9IA 5INWA 2D26A 2WXYC 5C98A 3T1PA 1SEKA 3H5CA 2ZV6A 1F0CA 2H4QA 4PYWA 4BB2A 1DB2A 1DZHL 1JJOC 1OPHA 3B9FI 3VVJA 2ACHA 2WXZC 2OL2A 7APIA 1MTPA 4C41A 1JTIA 4G8OA 4Y3KA 3UT3A 3NDFA 1OO8A 2B4XI 4ROBA 4AJUA 1IZ2A 1JVQI 2ANTI 4IF8A 5IO1A 4IC0A 1SR5A
chains in the Genus database with same CATH topology
2HIJL 2VH4A 3DY0A 2H4PA 3Q02A 1UHGA 1QMNA 1XQJA 1BY7A 2BEHI 1YXAA 2WXWA 9PAIA 5CDZA 1WZ9A 3PZFA 1C8OA 3NDAA 3PB1I 4EB1L 3DLWA 1DZGL 2V95A 3NE4A 2WXXA 1D5SA 5BRRI 1T1FA 1ATTA 4AU2A 3DRUA 4ZK0A 1IMVA 5HGCA 2R9YA 1JMJA 2B4XL 3Q03A 4RO9A 4DTEA 3CVMA 4Y40A 4DY0A 2QUGA 1C5GA 1OVAC 1K9OI 3NDDA 1HP7A 4DY7C 2OAYA 3OZQA 1XQGA 4G8RA 4AJTA 3STOA 1ATUA 1BR8I 2B5TI 1XU8A 1TB6I 3FGQA 2GD4C 3EOXA 2VDXA 2PEEA 4AQHA 5EI0A 2XN6A 4YIAA 1HLEA 8APIA 4AFXA 1EZXA 1DZHI 1DVNA 1PSIA 3F1SA 2XN5A 2CEOA 4AU3B 1LK6I 3F02A 2ARQA 4KDSA 1LJ5A 3CWLA 1AS4A 1OYHI 4X30A 4AU3A 3CWMA 3DRMA 2WY1A 2RIWA 2XN7A 4RSQA 2RIVA 3R4LA 1KCTA 2WXZA 4C49A 1SNGA 1QLPA 3F5NA 4ZK3A 1JMOA 2HIJI 3LW2A 1E05I 4P0FA 1JRRA 4CAAA 2BEHL 1QMBA 1ANTI 1OVAB 9APIA 2XN3A 1OC0A 1OVAA 2DUTA 5CDXA 1E04I 2HI9A 2H4RA 1LQ8A 2ARRA 4EB1I 1DZGI 1NQ9I 2ZNHA 1E03I 1OYHL 4AU4A 1ATHA 3CAAA 1A7CA 5CE0A 4GA7A 2WY0C 4ROAA 3KCGI 2VDYA 1M93B 1DVMA 1R1LI 4P0OA 1B3KA 3LE2A 1AZXI 3ZHAA 3EVJI 2PEFA 4R9IA 5INWA 2D26A 2WXYC 5C98A 3T1PA 1SEKA 3H5CA 2ZV6A 1F0CA 2H4QA 4PYWA 4BB2A 1DB2A 1DZHL 1JJOC 1OPHA 3B9FI 3VVJA 2ACHA 2WXZC 2OL2A 7APIA 1MTPA 4C41A 1JTIA 4G8OA 4Y3KA 3UT3A 3NDFA 1OO8A 2B4XI 4ROBA 4AJUA 1IZ2A 1JVQI 2ANTI 4IF8A 5IO1A 4IC0A 1SR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HIJ L;  2VH4 A;  3DY0 A;  2H4P A;  3Q02 A;  1UHG A;  1QMN A;  1XQJ A;  1BY7 A;  2BEH I;  1YXA A;  2WXW A;  9PAI A;  5CDZ A;  1WZ9 A;  3PZF A;  1C8O A;  3NDA A;  3PB1 I;  4EB1 L;  3DLW A;  1DZG L;  2V95 A;  3NE4 A;  2WXX A;  1D5S A;  5BRR I;  1T1F A;  1ATT A;  4AU2 A;  3DRU A;  4ZK0 A;  1IMV A;  5HGC A;  2R9Y A;  1JMJ A;  2B4X L;  3Q03 A;  4RO9 A;  4DTE A;  3CVM A;  4Y40 A;  4DY0 A;  2QUG A;  1C5G A;  1OVA C;  1K9O I;  3NDD A;  1HP7 A;  4DY7 C;  2OAY A;  3OZQ A;  1XQG A;  4G8R A;  4AJT A;  3STO A;  1ATU A;  1BR8 I;  2B5T I;  1XU8 A;  1TB6 I;  3FGQ A;  2GD4 C;  3EOX A;  2VDX A;  2PEE A;  4AQH A;  5EI0 A;  2XN6 A;  4YIA A;  1HLE A;  8API A;  4AFX A;  1EZX A;  1DZH I;  1DVN A;  1PSI A;  3F1S A;  2XN5 A;  2CEO A;  4AU3 B;  1LK6 I;  3F02 A;  2ARQ A;  4KDS A;  1LJ5 A;  3CWL A;  1AS4 A;  1OYH I;  4X30 A;  4AU3 A;  3CWM A;  3DRM A;  2WY1 A;  2RIW A;  2XN7 A;  4RSQ A;  2RIV A;  3R4L A;  1KCT A;  2WXZ A;  4C49 A;  1SNG A;  1QLP A;  3F5N A;  4ZK3 A;  1JMO A;  2HIJ I;  3LW2 A;  1E05 I;  4P0F A;  1JRR A;  4CAA A;  2BEH L;  1QMB A;  1ANT I;  1OVA B;  9API A;  2XN3 A;  1OC0 A;  1OVA A;  2DUT A;  5CDX A;  1E04 I;  2HI9 A;  2H4R A;  1LQ8 A;  2ARR A;  4EB1 I;  1DZG I;  1NQ9 I;  2ZNH A;  1E03 I;  1OYH L;  4AU4 A;  1ATH A;  3CAA A;  1A7C A;  5CE0 A;  4GA7 A;  2WY0 C;  4ROA A;  3KCG I;  2VDY A;  1M93 B;  1DVM A;  1R1L I;  4P0O A;  1B3K A;  3LE2 A;  1AZX I;  3ZHA A;  3EVJ I;  2PEF A;  4R9I A;  5INW A;  2D26 A;  2WXY C;  5C98 A;  3T1P A;  1SEK A;  3H5C A;  2ZV6 A;  1F0C A;  2H4Q A;  4PYW A;  4BB2 A;  1DB2 A;  1DZH L;  1JJO C;  1OPH A;  3B9F I;  3VVJ A;  2ACH A;  2WXZ C;  2OL2 A;  7API A;  1MTP A;  4C41 A;  1JTI A;  4G8O A;  4Y3K A;  3UT3 A;  3NDF A;  1OO8 A;  2B4X I;  4ROB A;  4AJU A;  1IZ2 A;  1JVQ I;  2ANT I;  4IF8 A;  5IO1 A;  4IC0 A;  1SR5 A; 
#chains in the Genus database with same CATH topology
 2HIJ L;  2VH4 A;  3DY0 A;  2H4P A;  3Q02 A;  1UHG A;  1QMN A;  1XQJ A;  1BY7 A;  2BEH I;  1YXA A;  2WXW A;  9PAI A;  5CDZ A;  1WZ9 A;  3PZF A;  1C8O A;  3NDA A;  3PB1 I;  4EB1 L;  3DLW A;  1DZG L;  2V95 A;  3NE4 A;  2WXX A;  1D5S A;  5BRR I;  1T1F A;  1ATT A;  4AU2 A;  3DRU A;  4ZK0 A;  1IMV A;  5HGC A;  2R9Y A;  1JMJ A;  2B4X L;  3Q03 A;  4RO9 A;  4DTE A;  3CVM A;  4Y40 A;  4DY0 A;  2QUG A;  1C5G A;  1OVA C;  1K9O I;  3NDD A;  1HP7 A;  4DY7 C;  2OAY A;  3OZQ A;  1XQG A;  4G8R A;  4AJT A;  3STO A;  1ATU A;  1BR8 I;  2B5T I;  1XU8 A;  1TB6 I;  3FGQ A;  2GD4 C;  3EOX A;  2VDX A;  2PEE A;  4AQH A;  5EI0 A;  2XN6 A;  4YIA A;  1HLE A;  8API A;  4AFX A;  1EZX A;  1DZH I;  1DVN A;  1PSI A;  3F1S A;  2XN5 A;  2CEO A;  4AU3 B;  1LK6 I;  3F02 A;  2ARQ A;  4KDS A;  1LJ5 A;  3CWL A;  1AS4 A;  1OYH I;  4X30 A;  4AU3 A;  3CWM A;  3DRM A;  2WY1 A;  2RIW A;  2XN7 A;  4RSQ A;  2RIV A;  3R4L A;  1KCT A;  2WXZ A;  4C49 A;  1SNG A;  1QLP A;  3F5N A;  4ZK3 A;  1JMO A;  2HIJ I;  3LW2 A;  1E05 I;  4P0F A;  1JRR A;  4CAA A;  2BEH L;  1QMB A;  1ANT I;  1OVA B;  9API A;  2XN3 A;  1OC0 A;  1OVA A;  2DUT A;  5CDX A;  1E04 I;  2HI9 A;  2H4R A;  1LQ8 A;  2ARR A;  4EB1 I;  1DZG I;  1NQ9 I;  2ZNH A;  1E03 I;  1OYH L;  4AU4 A;  1ATH A;  3CAA A;  1A7C A;  5CE0 A;  4GA7 A;  2WY0 C;  4ROA A;  3KCG I;  2VDY A;  1M93 B;  1DVM A;  1R1L I;  4P0O A;  1B3K A;  3LE2 A;  1AZX I;  3ZHA A;  3EVJ I;  2PEF A;  4R9I A;  5INW A;  2D26 A;  2WXY C;  5C98 A;  3T1P A;  1SEK A;  3H5C A;  2ZV6 A;  1F0C A;  2H4Q A;  4PYW A;  4BB2 A;  1DB2 A;  1DZH L;  1JJO C;  1OPH A;  3B9F I;  3VVJ A;  2ACH A;  2WXZ C;  2OL2 A;  7API A;  1MTP A;  4C41 A;  1JTI A;  4G8O A;  4Y3K A;  3UT3 A;  3NDF A;  1OO8 A;  2B4X I;  4ROB A;  4AJU A;  1IZ2 A;  1JVQ I;  2ANT I;  4IF8 A;  5IO1 A;  4IC0 A;  1SR5 A; 
#chains in the Genus database with same CATH homology
 2HIJ L;  2VH4 A;  3DY0 A;  2H4P A;  3Q02 A;  1UHG A;  1QMN A;  1XQJ A;  1BY7 A;  2BEH I;  1YXA A;  2WXW A;  9PAI A;  5CDZ A;  1WZ9 A;  3PZF A;  1C8O A;  3NDA A;  3PB1 I;  4EB1 L;  3DLW A;  1DZG L;  2V95 A;  3NE4 A;  2WXX A;  1D5S A;  5BRR I;  1T1F A;  1ATT A;  4AU2 A;  3DRU A;  4ZK0 A;  1IMV A;  5HGC A;  2R9Y A;  1JMJ A;  2B4X L;  3Q03 A;  4RO9 A;  4DTE A;  3CVM A;  4Y40 A;  4DY0 A;  2QUG A;  1C5G A;  1OVA C;  1K9O I;  3NDD A;  1HP7 A;  4DY7 C;  2OAY A;  3OZQ A;  1XQG A;  4G8R A;  4AJT A;  3STO A;  1ATU A;  1BR8 I;  2B5T I;  1XU8 A;  1TB6 I;  3FGQ A;  2GD4 C;  3EOX A;  2VDX A;  2PEE A;  4AQH A;  5EI0 A;  2XN6 A;  4YIA A;  1HLE A;  8API A;  4AFX A;  1EZX A;  1DZH I;  1DVN A;  1PSI A;  3F1S A;  2XN5 A;  2CEO A;  4AU3 B;  1LK6 I;  3F02 A;  2ARQ A;  4KDS A;  1LJ5 A;  3CWL A;  1AS4 A;  1OYH I;  4X30 A;  4AU3 A;  3CWM A;  3DRM A;  2WY1 A;  2RIW A;  2XN7 A;  4RSQ A;  2RIV A;  3R4L A;  1KCT A;  2WXZ A;  4C49 A;  1SNG A;  1QLP A;  3F5N A;  4ZK3 A;  1JMO A;  2HIJ I;  3LW2 A;  1E05 I;  4P0F A;  1JRR A;  4CAA A;  2BEH L;  1QMB A;  1ANT I;  1OVA B;  9API A;  2XN3 A;  1OC0 A;  1OVA A;  2DUT A;  5CDX A;  1E04 I;  2HI9 A;  2H4R A;  1LQ8 A;  2ARR A;  4EB1 I;  1DZG I;  1NQ9 I;  2ZNH A;  1E03 I;  1OYH L;  4AU4 A;  1ATH A;  3CAA A;  1A7C A;  5CE0 A;  4GA7 A;  2WY0 C;  4ROA A;  3KCG I;  2VDY A;  1M93 B;  1DVM A;  1R1L I;  4P0O A;  1B3K A;  3LE2 A;  1AZX I;  3ZHA A;  3EVJ I;  2PEF A;  4R9I A;  5INW A;  2D26 A;  2WXY C;  5C98 A;  3T1P A;  1SEK A;  3H5C A;  2ZV6 A;  1F0C A;  2H4Q A;  4PYW A;  4BB2 A;  1DB2 A;  1DZH L;  1JJO C;  1OPH A;  3B9F I;  3VVJ A;  2ACH A;  2WXZ C;  2OL2 A;  7API A;  1MTP A;  4C41 A;  1JTI A;  4G8O A;  4Y3K A;  3UT3 A;  3NDF A;  1OO8 A;  2B4X I;  4ROB A;  4AJU A;  1IZ2 A;  1JVQ I;  2ANT I;  4IF8 A;  5IO1 A;  4IC0 A;  1SR5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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