1XQJA

3.10 a crystal structure of maspin, space group i 4 2 2
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
378
structure length
378
Chain Sequence
QGSMDALQLANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSINSKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKASLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVSLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFSSP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
pubmed doi rcsb
molecule tags Antitumor protein
source organism Homo sapiens
molecule keywords Maspin
total genus 103
structure length 378
sequence length 378
ec nomenclature
pdb deposition date 2004-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 1xqjA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 1xqjA01
2RIVA 3PB1I 2PEFA 3DLWA 3EOXA 4G8OA 2H4QA 1UHGA 4AFXA 1SR5A 8APIA 2WY0C 1A7CA 1QMBA 4ROAA 2B5TI 1QMNA 1LK6I 2GD4C 2WXXA 1JMOA 3CAAA 4ZK3A 4R9IA 2HIJI 5HGCA 2VDXA 4RSQA 1D5SA 3EVJI 1E03I 3T1PA 4AU4A 1OVAA 2VH4A 3F1SA 2WXYC 3NDDA 4AU3A 1HP7A 3LE2A 3F5NA 1R1LI 4X30A 2VDYA 1F0CA 3Q03A 1OVAC 1DB2A 2PEEA 1BY7A 1ATTA 1T1FA 2DUTA 1NQ9I 1OC0A 3FGQA 4CAAA 3ZHAA 5BRRI 1OYHL 2ZV6A 1C5GA 1OO8A 4P0FA 5CDZA 1AZXI 1DZGI 3CWLA 1JJOC 1QLPA 1ATHA 1DVMA 2WXWA 2ANTI 4AJTA 4EB1I 2B4XI 4Y40A 1E05I 1OVAB 2D26A 2BEHL 3DY0A 1AS4A 4YIAA 2ARQA 9PAIA 3NDFA 5INWA 2H4PA 4AU3B 2HI9A 1K9OI 2XN7A 1OPHA 3B9FI 3PZFA 4AQHA 3CWMA 9APIA 1JTIA 3CVMA 3DRUA 1DZHL 3NDAA 5EI0A 1XU8A 2OL2A 1JMJA 4DY7C 1SNGA 1B3KA 5IO1A 2H4RA 3NE4A 4RO9A 2HIJL 1OYHI 4AJUA 1ANTI 4KDSA 2CEOA 2WY1A 1LQ8A 2XN5A 1JRRA 1M93B 4P0OA 1HLEA 3Q02A 2XN6A 2ZNHA 4ROBA 4ZK0A 2R9YA 2WXZA 1C8OA 2QUGA 1WZ9A 1YXAA 4G8RA 5CDXA 1IZ2A 1IMVA 3KCGI 3OZQA 4BB2A 5CE0A 3STOA 2V95A 2OAYA 4IF8A 1BR8I 4PYWA 4C49A 1EZXA 5C98A 4C41A 7APIA 1DZHI 2WXZC 1XQJA 1SEKA 3VVJA 4IC0A 1LJ5A 2ARRA 1DVNA 2XN3A 1KCTA 4DTEA 1DZGL 3F02A 4AU2A 1E04I 2ACHA 3H5CA 4Y3KA 4EB1L 2B4XL 4GA7A 1JVQI 1XQGA 4DY0A 2RIWA 1PSIA 1TB6I 1ATUA 3LW2A 1MTPA 3R4LA 3DRMA 3UT3A 2BEHI
chains in the Genus database with same CATH superfamily
2RIVA 3PB1I 2PEFA 3DLWA 3EOXA 4G8OA 2H4QA 1UHGA 4AFXA 1SR5A 8APIA 2WY0C 1A7CA 1QMBA 4ROAA 2B5TI 1QMNA 1LK6I 2GD4C 2WXXA 1JMOA 3CAAA 4ZK3A 4R9IA 2HIJI 5HGCA 2VDXA 4RSQA 1D5SA 3EVJI 1E03I 3T1PA 4AU4A 1OVAA 2VH4A 3F1SA 2WXYC 3NDDA 4AU3A 1HP7A 3LE2A 3F5NA 1R1LI 4X30A 2VDYA 1F0CA 3Q03A 1OVAC 1DB2A 2PEEA 1BY7A 1ATTA 1T1FA 2DUTA 1NQ9I 1OC0A 3FGQA 4CAAA 3ZHAA 5BRRI 1OYHL 2ZV6A 1C5GA 1OO8A 4P0FA 5CDZA 1AZXI 1DZGI 3CWLA 1JJOC 1QLPA 1ATHA 1DVMA 2WXWA 2ANTI 4AJTA 4EB1I 2B4XI 4Y40A 1E05I 1OVAB 2D26A 2BEHL 3DY0A 1AS4A 4YIAA 2ARQA 9PAIA 3NDFA 5INWA 2H4PA 4AU3B 2HI9A 1K9OI 2XN7A 1OPHA 3B9FI 3PZFA 4AQHA 3CWMA 9APIA 1JTIA 3CVMA 3DRUA 1DZHL 3NDAA 5EI0A 1XU8A 2OL2A 1JMJA 4DY7C 1SNGA 1B3KA 5IO1A 2H4RA 3NE4A 4RO9A 2HIJL 1OYHI 4AJUA 1ANTI 4KDSA 2CEOA 2WY1A 1LQ8A 2XN5A 1JRRA 1M93B 4P0OA 1HLEA 3Q02A 2XN6A 2ZNHA 4ROBA 4ZK0A 2R9YA 2WXZA 1C8OA 2QUGA 1WZ9A 1YXAA 4G8RA 5CDXA 1IZ2A 1IMVA 3KCGI 3OZQA 4BB2A 5CE0A 3STOA 2V95A 2OAYA 4IF8A 1BR8I 4PYWA 4C49A 1EZXA 5C98A 4C41A 7APIA 1DZHI 2WXZC 1XQJA 1SEKA 3VVJA 4IC0A 1LJ5A 2ARRA 1DVNA 2XN3A 1KCTA 4DTEA 1DZGL 3F02A 4AU2A 1E04I 2ACHA 3H5CA 4Y3KA 4EB1L 2B4XL 4GA7A 1JVQI 1XQGA 4DY0A 2RIWA 1PSIA 1TB6I 1ATUA 3LW2A 1MTPA 3R4LA 3DRMA 3UT3A 2BEHI
chains in the Genus database with same CATH topology
2RIVA 3PB1I 2PEFA 3DLWA 3EOXA 4G8OA 2H4QA 1UHGA 4AFXA 1SR5A 8APIA 2WY0C 1A7CA 1QMBA 4ROAA 2B5TI 1QMNA 1LK6I 2GD4C 2WXXA 1JMOA 3CAAA 4ZK3A 4R9IA 2HIJI 5HGCA 2VDXA 4RSQA 1D5SA 3EVJI 1E03I 3T1PA 4AU4A 1OVAA 2VH4A 3F1SA 2WXYC 3NDDA 4AU3A 1HP7A 3LE2A 3F5NA 1R1LI 4X30A 2VDYA 1F0CA 3Q03A 1OVAC 1DB2A 2PEEA 1BY7A 1ATTA 1T1FA 2DUTA 1NQ9I 1OC0A 3FGQA 4CAAA 3ZHAA 5BRRI 1OYHL 2ZV6A 1C5GA 1OO8A 4P0FA 5CDZA 1AZXI 1DZGI 3CWLA 1JJOC 1QLPA 1ATHA 1DVMA 2WXWA 2ANTI 4AJTA 4EB1I 2B4XI 4Y40A 1E05I 1OVAB 2D26A 2BEHL 3DY0A 1AS4A 4YIAA 2ARQA 9PAIA 3NDFA 5INWA 2H4PA 4AU3B 2HI9A 1K9OI 2XN7A 1OPHA 3B9FI 3PZFA 4AQHA 3CWMA 9APIA 1JTIA 3CVMA 3DRUA 1DZHL 3NDAA 5EI0A 1XU8A 2OL2A 1JMJA 4DY7C 1SNGA 1B3KA 5IO1A 2H4RA 3NE4A 4RO9A 2HIJL 1OYHI 4AJUA 1ANTI 4KDSA 2CEOA 2WY1A 1LQ8A 2XN5A 1JRRA 1M93B 4P0OA 1HLEA 3Q02A 2XN6A 2ZNHA 4ROBA 4ZK0A 2R9YA 2WXZA 1C8OA 2QUGA 1WZ9A 1YXAA 4G8RA 5CDXA 1IZ2A 1IMVA 3KCGI 3OZQA 4BB2A 5CE0A 3STOA 2V95A 2OAYA 4IF8A 1BR8I 4PYWA 4C49A 1EZXA 5C98A 4C41A 7APIA 1DZHI 2WXZC 1XQJA 1SEKA 3VVJA 4IC0A 1LJ5A 2ARRA 1DVNA 2XN3A 1KCTA 4DTEA 1DZGL 3F02A 4AU2A 1E04I 2ACHA 3H5CA 4Y3KA 4EB1L 2B4XL 4GA7A 1JVQI 1XQGA 4DY0A 2RIWA 1PSIA 1TB6I 1ATUA 3LW2A 1MTPA 3R4LA 3DRMA 3UT3A 2BEHI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RIV A;  3PB1 I;  2PEF A;  3DLW A;  3EOX A;  4G8O A;  2H4Q A;  1UHG A;  4AFX A;  1SR5 A;  8API A;  2WY0 C;  1A7C A;  1QMB A;  4ROA A;  2B5T I;  1QMN A;  1LK6 I;  2GD4 C;  2WXX A;  1JMO A;  3CAA A;  4ZK3 A;  4R9I A;  2HIJ I;  5HGC A;  2VDX A;  4RSQ A;  1D5S A;  3EVJ I;  1E03 I;  3T1P A;  4AU4 A;  1OVA A;  2VH4 A;  3F1S A;  2WXY C;  3NDD A;  4AU3 A;  1HP7 A;  3LE2 A;  3F5N A;  1R1L I;  4X30 A;  2VDY A;  1F0C A;  3Q03 A;  1OVA C;  1DB2 A;  2PEE A;  1BY7 A;  1ATT A;  1T1F A;  2DUT A;  1NQ9 I;  1OC0 A;  3FGQ A;  4CAA A;  3ZHA A;  5BRR I;  1OYH L;  2ZV6 A;  1C5G A;  1OO8 A;  4P0F A;  5CDZ A;  1AZX I;  1DZG I;  3CWL A;  1JJO C;  1QLP A;  1ATH A;  1DVM A;  2WXW A;  2ANT I;  4AJT A;  4EB1 I;  2B4X I;  4Y40 A;  1E05 I;  1OVA B;  2D26 A;  2BEH L;  3DY0 A;  1AS4 A;  4YIA A;  2ARQ A;  9PAI A;  3NDF A;  5INW A;  2H4P A;  4AU3 B;  2HI9 A;  1K9O I;  2XN7 A;  1OPH A;  3B9F I;  3PZF A;  4AQH A;  3CWM A;  9API A;  1JTI A;  3CVM A;  3DRU A;  1DZH L;  3NDA A;  5EI0 A;  1XU8 A;  2OL2 A;  1JMJ A;  4DY7 C;  1SNG A;  1B3K A;  5IO1 A;  2H4R A;  3NE4 A;  4RO9 A;  2HIJ L;  1OYH I;  4AJU A;  1ANT I;  4KDS A;  2CEO A;  2WY1 A;  1LQ8 A;  2XN5 A;  1JRR A;  1M93 B;  4P0O A;  1HLE A;  3Q02 A;  2XN6 A;  2ZNH A;  4ROB A;  4ZK0 A;  2R9Y A;  2WXZ A;  1C8O A;  2QUG A;  1WZ9 A;  1YXA A;  4G8R A;  5CDX A;  1IZ2 A;  1IMV A;  3KCG I;  3OZQ A;  4BB2 A;  5CE0 A;  3STO A;  2V95 A;  2OAY A;  4IF8 A;  1BR8 I;  4PYW A;  4C49 A;  1EZX A;  5C98 A;  4C41 A;  7API A;  1DZH I;  2WXZ C;  1XQJ A;  1SEK A;  3VVJ A;  4IC0 A;  1LJ5 A;  2ARR A;  1DVN A;  2XN3 A;  1KCT A;  4DTE A;  1DZG L;  3F02 A;  4AU2 A;  1E04 I;  2ACH A;  3H5C A;  4Y3K A;  4EB1 L;  2B4X L;  4GA7 A;  1JVQ I;  1XQG A;  4DY0 A;  2RIW A;  1PSI A;  1TB6 I;  1ATU A;  3LW2 A;  1MTP A;  3R4L A;  3DRM A;  3UT3 A;  2BEH I; 
#chains in the Genus database with same CATH topology
 2RIV A;  3PB1 I;  2PEF A;  3DLW A;  3EOX A;  4G8O A;  2H4Q A;  1UHG A;  4AFX A;  1SR5 A;  8API A;  2WY0 C;  1A7C A;  1QMB A;  4ROA A;  2B5T I;  1QMN A;  1LK6 I;  2GD4 C;  2WXX A;  1JMO A;  3CAA A;  4ZK3 A;  4R9I A;  2HIJ I;  5HGC A;  2VDX A;  4RSQ A;  1D5S A;  3EVJ I;  1E03 I;  3T1P A;  4AU4 A;  1OVA A;  2VH4 A;  3F1S A;  2WXY C;  3NDD A;  4AU3 A;  1HP7 A;  3LE2 A;  3F5N A;  1R1L I;  4X30 A;  2VDY A;  1F0C A;  3Q03 A;  1OVA C;  1DB2 A;  2PEE A;  1BY7 A;  1ATT A;  1T1F A;  2DUT A;  1NQ9 I;  1OC0 A;  3FGQ A;  4CAA A;  3ZHA A;  5BRR I;  1OYH L;  2ZV6 A;  1C5G A;  1OO8 A;  4P0F A;  5CDZ A;  1AZX I;  1DZG I;  3CWL A;  1JJO C;  1QLP A;  1ATH A;  1DVM A;  2WXW A;  2ANT I;  4AJT A;  4EB1 I;  2B4X I;  4Y40 A;  1E05 I;  1OVA B;  2D26 A;  2BEH L;  3DY0 A;  1AS4 A;  4YIA A;  2ARQ A;  9PAI A;  3NDF A;  5INW A;  2H4P A;  4AU3 B;  2HI9 A;  1K9O I;  2XN7 A;  1OPH A;  3B9F I;  3PZF A;  4AQH A;  3CWM A;  9API A;  1JTI A;  3CVM A;  3DRU A;  1DZH L;  3NDA A;  5EI0 A;  1XU8 A;  2OL2 A;  1JMJ A;  4DY7 C;  1SNG A;  1B3K A;  5IO1 A;  2H4R A;  3NE4 A;  4RO9 A;  2HIJ L;  1OYH I;  4AJU A;  1ANT I;  4KDS A;  2CEO A;  2WY1 A;  1LQ8 A;  2XN5 A;  1JRR A;  1M93 B;  4P0O A;  1HLE A;  3Q02 A;  2XN6 A;  2ZNH A;  4ROB A;  4ZK0 A;  2R9Y A;  2WXZ A;  1C8O A;  2QUG A;  1WZ9 A;  1YXA A;  4G8R A;  5CDX A;  1IZ2 A;  1IMV A;  3KCG I;  3OZQ A;  4BB2 A;  5CE0 A;  3STO A;  2V95 A;  2OAY A;  4IF8 A;  1BR8 I;  4PYW A;  4C49 A;  1EZX A;  5C98 A;  4C41 A;  7API A;  1DZH I;  2WXZ C;  1XQJ A;  1SEK A;  3VVJ A;  4IC0 A;  1LJ5 A;  2ARR A;  1DVN A;  2XN3 A;  1KCT A;  4DTE A;  1DZG L;  3F02 A;  4AU2 A;  1E04 I;  2ACH A;  3H5C A;  4Y3K A;  4EB1 L;  2B4X L;  4GA7 A;  1JVQ I;  1XQG A;  4DY0 A;  2RIW A;  1PSI A;  1TB6 I;  1ATU A;  3LW2 A;  1MTP A;  3R4L A;  3DRM A;  3UT3 A;  2BEH I; 
#chains in the Genus database with same CATH homology
 2RIV A;  3PB1 I;  2PEF A;  3DLW A;  3EOX A;  4G8O A;  2H4Q A;  1UHG A;  4AFX A;  1SR5 A;  8API A;  2WY0 C;  1A7C A;  1QMB A;  4ROA A;  2B5T I;  1QMN A;  1LK6 I;  2GD4 C;  2WXX A;  1JMO A;  3CAA A;  4ZK3 A;  4R9I A;  2HIJ I;  5HGC A;  2VDX A;  4RSQ A;  1D5S A;  3EVJ I;  1E03 I;  3T1P A;  4AU4 A;  1OVA A;  2VH4 A;  3F1S A;  2WXY C;  3NDD A;  4AU3 A;  1HP7 A;  3LE2 A;  3F5N A;  1R1L I;  4X30 A;  2VDY A;  1F0C A;  3Q03 A;  1OVA C;  1DB2 A;  2PEE A;  1BY7 A;  1ATT A;  1T1F A;  2DUT A;  1NQ9 I;  1OC0 A;  3FGQ A;  4CAA A;  3ZHA A;  5BRR I;  1OYH L;  2ZV6 A;  1C5G A;  1OO8 A;  4P0F A;  5CDZ A;  1AZX I;  1DZG I;  3CWL A;  1JJO C;  1QLP A;  1ATH A;  1DVM A;  2WXW A;  2ANT I;  4AJT A;  4EB1 I;  2B4X I;  4Y40 A;  1E05 I;  1OVA B;  2D26 A;  2BEH L;  3DY0 A;  1AS4 A;  4YIA A;  2ARQ A;  9PAI A;  3NDF A;  5INW A;  2H4P A;  4AU3 B;  2HI9 A;  1K9O I;  2XN7 A;  1OPH A;  3B9F I;  3PZF A;  4AQH A;  3CWM A;  9API A;  1JTI A;  3CVM A;  3DRU A;  1DZH L;  3NDA A;  5EI0 A;  1XU8 A;  2OL2 A;  1JMJ A;  4DY7 C;  1SNG A;  1B3K A;  5IO1 A;  2H4R A;  3NE4 A;  4RO9 A;  2HIJ L;  1OYH I;  4AJU A;  1ANT I;  4KDS A;  2CEO A;  2WY1 A;  1LQ8 A;  2XN5 A;  1JRR A;  1M93 B;  4P0O A;  1HLE A;  3Q02 A;  2XN6 A;  2ZNH A;  4ROB A;  4ZK0 A;  2R9Y A;  2WXZ A;  1C8O A;  2QUG A;  1WZ9 A;  1YXA A;  4G8R A;  5CDX A;  1IZ2 A;  1IMV A;  3KCG I;  3OZQ A;  4BB2 A;  5CE0 A;  3STO A;  2V95 A;  2OAY A;  4IF8 A;  1BR8 I;  4PYW A;  4C49 A;  1EZX A;  5C98 A;  4C41 A;  7API A;  1DZH I;  2WXZ C;  1XQJ A;  1SEK A;  3VVJ A;  4IC0 A;  1LJ5 A;  2ARR A;  1DVN A;  2XN3 A;  1KCT A;  4DTE A;  1DZG L;  3F02 A;  4AU2 A;  1E04 I;  2ACH A;  3H5C A;  4Y3K A;  4EB1 L;  2B4X L;  4GA7 A;  1JVQ I;  1XQG A;  4DY0 A;  2RIW A;  1PSI A;  1TB6 I;  1ATU A;  3LW2 A;  1MTP A;  3R4L A;  3DRM A;  3UT3 A;  2BEH I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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