1HLEA

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 angstroms resolution
Total Genus 102
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
344
structure length
344
Chain Sequence
MEQLSTANTHFAVDLFRALNESDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDTVEDIHSRFQSLNADINKPGAPYILKLANRLYGEKTYNFLADFLASTQKMYGAELASVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKFMKEATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIEDLKCRVLELPYQGKELSMIILLPDDIEDESTGLEKIEKQLTLDKLREWTKPENLYLAEVNVHLPRFKLEESYDLTSHLARLGVQDLFNRGKADLSGMSGARDLFVSKIIHKSFVDLNEEGTEAAAATAGTILLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution.
pubmed doi rcsb
molecule tags Hydrolase inhibitor(serine proteinase)
source organism Equus caballus
molecule keywords HORSE LEUKOCYTE ELASTASE INHIBITOR
total genus 102
structure length 344
sequence length 344
ec nomenclature
pdb deposition date 1992-04-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 1hleA01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 1hleA02
2B5TI 5INWA 2V95A 4AU3B 1DB2A 2WY0C 2WXZC 1C5GA 4EB1I 1HLEA 1C8OA 4YIAA 1DVNA 2VDYA 3B9FI 4AU4A 1OPHA 3KCGI 1M93B 3NDFA 4C49A 2D26A 2XN5A 2H4RA 2VH4A 1SNGA 2WY1A 2XN3A 1AZXI 5BRRI 2B4XI 1HP7A 1QMBA 2WXZA 3PZFA 2OL2A 1K9OI 3DLWA 1LQ8A 3NDDA 4CAAA 1YXAA 1R1LI 3DRMA 1KCTA 3CVMA 3DY0A 1TB6I 3T1PA 5C98A 1QMNA 3CWMA 2R9YA 1E05I 4DY0A 2HI9A 4AQHA 1LJ5A 2RIVA 9APIA 1EZXA 1OVAB 2OAYA 2CEOA 4IC0A 4RO9A 1ANTI 1IZ2A 1AS4A 4P0FA 1JMOA 1OVAC 3EVJI 5HGCA 1E04I 2H4PA 1WZ9A 3NE4A 2RIWA 1XU8A 1NQ9I 1BR8I 4RSQA 3DRUA 1JMJA 2ARRA 4Y40A 2ZNHA 4R9IA 1B3KA 3F1SA 2XN7A 1IMVA 4GA7A 1OVAA 1D5SA 2ZV6A 4X30A 2GD4C 2PEEA 4AU2A 7APIA 3UT3A 4ROAA 1DZHL 4ROBA 2ARQA 1ATUA 8APIA 1OYHL 4G8OA 3F5NA 1F0CA 2QUGA 3OZQA 4AFXA 3CWLA 1JTIA 2DUTA 2VDXA 3FGQA 3Q02A 1DZGL 2ACHA 3CAAA 2HIJL 5CE0A 4AJTA 2BEHL 4C41A 4G8RA 2ANTI 1T1FA 1OO8A 1OC0A 2PEFA 4ZK0A 1SEKA 2WXYC 3ZHAA 2XN6A 1JRRA 4PYWA 9PAIA 4EB1L 1UHGA 4Y3KA 2WXXA 3LW2A 4DTEA 1DVMA 4IF8A 3H5CA 1JVQI 1ATHA 5EI0A 2WXWA 1DZHI 2H4QA 4KDSA 3STOA 3NDAA 2B4XL 1OYHI 3EOXA 4BB2A 1ATTA 1XQJA 3LE2A 3R4LA 1DZGI 1LK6I 3VVJA 1XQGA 5CDXA 5CDZA 3PB1I 4DY7C 5IO1A 2HIJI 1E03I 1MTPA 1A7CA 1JJOC 4AU3A 1PSIA 4P0OA 2BEHI 3Q03A 4AJUA 1BY7A 3F02A 1SR5A 4ZK3A 1QLPA
chains in the Genus database with same CATH superfamily
2B5TI 5INWA 2V95A 4AU3B 1DB2A 2WY0C 2WXZC 1C5GA 4EB1I 1HLEA 1C8OA 4YIAA 1DVNA 2VDYA 3B9FI 4AU4A 1OPHA 3KCGI 1M93B 3NDFA 4C49A 2D26A 2XN5A 2H4RA 2VH4A 1SNGA 2WY1A 2XN3A 1AZXI 5BRRI 2B4XI 1HP7A 1QMBA 2WXZA 3PZFA 2OL2A 1K9OI 3DLWA 1LQ8A 3NDDA 4CAAA 1YXAA 1R1LI 3DRMA 1KCTA 3CVMA 3DY0A 1TB6I 3T1PA 5C98A 1QMNA 3CWMA 2R9YA 1E05I 4DY0A 2HI9A 4AQHA 1LJ5A 2RIVA 9APIA 1EZXA 1OVAB 2OAYA 2CEOA 4IC0A 4RO9A 1ANTI 1IZ2A 1AS4A 4P0FA 1JMOA 1OVAC 3EVJI 5HGCA 1E04I 2H4PA 1WZ9A 3NE4A 2RIWA 1XU8A 1NQ9I 1BR8I 4RSQA 3DRUA 1JMJA 2ARRA 4Y40A 2ZNHA 4R9IA 1B3KA 3F1SA 2XN7A 1IMVA 4GA7A 1OVAA 1D5SA 2ZV6A 4X30A 2GD4C 2PEEA 4AU2A 7APIA 3UT3A 4ROAA 1DZHL 4ROBA 2ARQA 1ATUA 8APIA 1OYHL 4G8OA 3F5NA 1F0CA 2QUGA 3OZQA 4AFXA 3CWLA 1JTIA 2DUTA 2VDXA 3FGQA 3Q02A 1DZGL 2ACHA 3CAAA 2HIJL 5CE0A 4AJTA 2BEHL 4C41A 4G8RA 2ANTI 1T1FA 1OO8A 1OC0A 2PEFA 4ZK0A 1SEKA 2WXYC 3ZHAA 2XN6A 1JRRA 4PYWA 9PAIA 4EB1L 1UHGA 4Y3KA 2WXXA 3LW2A 4DTEA 1DVMA 4IF8A 3H5CA 1JVQI 1ATHA 5EI0A 2WXWA 1DZHI 2H4QA 4KDSA 3STOA 3NDAA 2B4XL 1OYHI 3EOXA 4BB2A 1ATTA 1XQJA 3LE2A 3R4LA 1DZGI 1LK6I 3VVJA 1XQGA 5CDXA 5CDZA 3PB1I 4DY7C 5IO1A 2HIJI 1E03I 1MTPA 1A7CA 1JJOC 4AU3A 1PSIA 4P0OA 2BEHI 3Q03A 4AJUA 1BY7A 3F02A 1SR5A 4ZK3A 1QLPA
chains in the Genus database with same CATH topology
2B5TI 5INWA 2V95A 4AU3B 1DB2A 2WY0C 2WXZC 1C5GA 4EB1I 1HLEA 1C8OA 4YIAA 1DVNA 2VDYA 3B9FI 4AU4A 1OPHA 3KCGI 1M93B 3NDFA 4C49A 2D26A 2XN5A 2H4RA 2VH4A 1SNGA 2WY1A 2XN3A 1AZXI 5BRRI 2B4XI 1HP7A 1QMBA 2WXZA 3PZFA 2OL2A 1K9OI 3DLWA 1LQ8A 3NDDA 4CAAA 1YXAA 1R1LI 3DRMA 1KCTA 3CVMA 3DY0A 1TB6I 3T1PA 5C98A 1QMNA 3CWMA 2R9YA 1E05I 4DY0A 2HI9A 4AQHA 1LJ5A 2RIVA 9APIA 1EZXA 1OVAB 2OAYA 2CEOA 4IC0A 4RO9A 1ANTI 1IZ2A 1AS4A 4P0FA 1JMOA 1OVAC 3EVJI 5HGCA 1E04I 2H4PA 1WZ9A 3NE4A 2RIWA 1XU8A 1NQ9I 1BR8I 4RSQA 3DRUA 1JMJA 2ARRA 4Y40A 2ZNHA 4R9IA 1B3KA 3F1SA 2XN7A 1IMVA 4GA7A 1OVAA 1D5SA 2ZV6A 4X30A 2GD4C 2PEEA 4AU2A 7APIA 3UT3A 4ROAA 1DZHL 4ROBA 2ARQA 1ATUA 8APIA 1OYHL 4G8OA 3F5NA 1F0CA 2QUGA 3OZQA 4AFXA 3CWLA 1JTIA 2DUTA 2VDXA 3FGQA 3Q02A 1DZGL 2ACHA 3CAAA 2HIJL 5CE0A 4AJTA 2BEHL 4C41A 4G8RA 2ANTI 1T1FA 1OO8A 1OC0A 2PEFA 4ZK0A 1SEKA 2WXYC 3ZHAA 2XN6A 1JRRA 4PYWA 9PAIA 4EB1L 1UHGA 4Y3KA 2WXXA 3LW2A 4DTEA 1DVMA 4IF8A 3H5CA 1JVQI 1ATHA 5EI0A 2WXWA 1DZHI 2H4QA 4KDSA 3STOA 3NDAA 2B4XL 1OYHI 3EOXA 4BB2A 1ATTA 1XQJA 3LE2A 3R4LA 1DZGI 1LK6I 3VVJA 1XQGA 5CDXA 5CDZA 3PB1I 4DY7C 5IO1A 2HIJI 1E03I 1MTPA 1A7CA 1JJOC 4AU3A 1PSIA 4P0OA 2BEHI 3Q03A 4AJUA 1BY7A 3F02A 1SR5A 4ZK3A 1QLPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B5T I;  5INW A;  2V95 A;  4AU3 B;  1DB2 A;  2WY0 C;  2WXZ C;  1C5G A;  4EB1 I;  1HLE A;  1C8O A;  4YIA A;  1DVN A;  2VDY A;  3B9F I;  4AU4 A;  1OPH A;  3KCG I;  1M93 B;  3NDF A;  4C49 A;  2D26 A;  2XN5 A;  2H4R A;  2VH4 A;  1SNG A;  2WY1 A;  2XN3 A;  1AZX I;  5BRR I;  2B4X I;  1HP7 A;  1QMB A;  2WXZ A;  3PZF A;  2OL2 A;  1K9O I;  3DLW A;  1LQ8 A;  3NDD A;  4CAA A;  1YXA A;  1R1L I;  3DRM A;  1KCT A;  3CVM A;  3DY0 A;  1TB6 I;  3T1P A;  5C98 A;  1QMN A;  3CWM A;  2R9Y A;  1E05 I;  4DY0 A;  2HI9 A;  4AQH A;  1LJ5 A;  2RIV A;  9API A;  1EZX A;  1OVA B;  2OAY A;  2CEO A;  4IC0 A;  4RO9 A;  1ANT I;  1IZ2 A;  1AS4 A;  4P0F A;  1JMO A;  1OVA C;  3EVJ I;  5HGC A;  1E04 I;  2H4P A;  1WZ9 A;  3NE4 A;  2RIW A;  1XU8 A;  1NQ9 I;  1BR8 I;  4RSQ A;  3DRU A;  1JMJ A;  2ARR A;  4Y40 A;  2ZNH A;  4R9I A;  1B3K A;  3F1S A;  2XN7 A;  1IMV A;  4GA7 A;  1OVA A;  1D5S A;  2ZV6 A;  4X30 A;  2GD4 C;  2PEE A;  4AU2 A;  7API A;  3UT3 A;  4ROA A;  1DZH L;  4ROB A;  2ARQ A;  1ATU A;  8API A;  1OYH L;  4G8O A;  3F5N A;  1F0C A;  2QUG A;  3OZQ A;  4AFX A;  3CWL A;  1JTI A;  2DUT A;  2VDX A;  3FGQ A;  3Q02 A;  1DZG L;  2ACH A;  3CAA A;  2HIJ L;  5CE0 A;  4AJT A;  2BEH L;  4C41 A;  4G8R A;  2ANT I;  1T1F A;  1OO8 A;  1OC0 A;  2PEF A;  4ZK0 A;  1SEK A;  2WXY C;  3ZHA A;  2XN6 A;  1JRR A;  4PYW A;  9PAI A;  4EB1 L;  1UHG A;  4Y3K A;  2WXX A;  3LW2 A;  4DTE A;  1DVM A;  4IF8 A;  3H5C A;  1JVQ I;  1ATH A;  5EI0 A;  2WXW A;  1DZH I;  2H4Q A;  4KDS A;  3STO A;  3NDA A;  2B4X L;  1OYH I;  3EOX A;  4BB2 A;  1ATT A;  1XQJ A;  3LE2 A;  3R4L A;  1DZG I;  1LK6 I;  3VVJ A;  1XQG A;  5CDX A;  5CDZ A;  3PB1 I;  4DY7 C;  5IO1 A;  2HIJ I;  1E03 I;  1MTP A;  1A7C A;  1JJO C;  4AU3 A;  1PSI A;  4P0O A;  2BEH I;  3Q03 A;  4AJU A;  1BY7 A;  3F02 A;  1SR5 A;  4ZK3 A;  1QLP A; 
#chains in the Genus database with same CATH topology
 2B5T I;  5INW A;  2V95 A;  4AU3 B;  1DB2 A;  2WY0 C;  2WXZ C;  1C5G A;  4EB1 I;  1HLE A;  1C8O A;  4YIA A;  1DVN A;  2VDY A;  3B9F I;  4AU4 A;  1OPH A;  3KCG I;  1M93 B;  3NDF A;  4C49 A;  2D26 A;  2XN5 A;  2H4R A;  2VH4 A;  1SNG A;  2WY1 A;  2XN3 A;  1AZX I;  5BRR I;  2B4X I;  1HP7 A;  1QMB A;  2WXZ A;  3PZF A;  2OL2 A;  1K9O I;  3DLW A;  1LQ8 A;  3NDD A;  4CAA A;  1YXA A;  1R1L I;  3DRM A;  1KCT A;  3CVM A;  3DY0 A;  1TB6 I;  3T1P A;  5C98 A;  1QMN A;  3CWM A;  2R9Y A;  1E05 I;  4DY0 A;  2HI9 A;  4AQH A;  1LJ5 A;  2RIV A;  9API A;  1EZX A;  1OVA B;  2OAY A;  2CEO A;  4IC0 A;  4RO9 A;  1ANT I;  1IZ2 A;  1AS4 A;  4P0F A;  1JMO A;  1OVA C;  3EVJ I;  5HGC A;  1E04 I;  2H4P A;  1WZ9 A;  3NE4 A;  2RIW A;  1XU8 A;  1NQ9 I;  1BR8 I;  4RSQ A;  3DRU A;  1JMJ A;  2ARR A;  4Y40 A;  2ZNH A;  4R9I A;  1B3K A;  3F1S A;  2XN7 A;  1IMV A;  4GA7 A;  1OVA A;  1D5S A;  2ZV6 A;  4X30 A;  2GD4 C;  2PEE A;  4AU2 A;  7API A;  3UT3 A;  4ROA A;  1DZH L;  4ROB A;  2ARQ A;  1ATU A;  8API A;  1OYH L;  4G8O A;  3F5N A;  1F0C A;  2QUG A;  3OZQ A;  4AFX A;  3CWL A;  1JTI A;  2DUT A;  2VDX A;  3FGQ A;  3Q02 A;  1DZG L;  2ACH A;  3CAA A;  2HIJ L;  5CE0 A;  4AJT A;  2BEH L;  4C41 A;  4G8R A;  2ANT I;  1T1F A;  1OO8 A;  1OC0 A;  2PEF A;  4ZK0 A;  1SEK A;  2WXY C;  3ZHA A;  2XN6 A;  1JRR A;  4PYW A;  9PAI A;  4EB1 L;  1UHG A;  4Y3K A;  2WXX A;  3LW2 A;  4DTE A;  1DVM A;  4IF8 A;  3H5C A;  1JVQ I;  1ATH A;  5EI0 A;  2WXW A;  1DZH I;  2H4Q A;  4KDS A;  3STO A;  3NDA A;  2B4X L;  1OYH I;  3EOX A;  4BB2 A;  1ATT A;  1XQJ A;  3LE2 A;  3R4L A;  1DZG I;  1LK6 I;  3VVJ A;  1XQG A;  5CDX A;  5CDZ A;  3PB1 I;  4DY7 C;  5IO1 A;  2HIJ I;  1E03 I;  1MTP A;  1A7C A;  1JJO C;  4AU3 A;  1PSI A;  4P0O A;  2BEH I;  3Q03 A;  4AJU A;  1BY7 A;  3F02 A;  1SR5 A;  4ZK3 A;  1QLP A; 
#chains in the Genus database with same CATH homology
 2B5T I;  5INW A;  2V95 A;  4AU3 B;  1DB2 A;  2WY0 C;  2WXZ C;  1C5G A;  4EB1 I;  1HLE A;  1C8O A;  4YIA A;  1DVN A;  2VDY A;  3B9F I;  4AU4 A;  1OPH A;  3KCG I;  1M93 B;  3NDF A;  4C49 A;  2D26 A;  2XN5 A;  2H4R A;  2VH4 A;  1SNG A;  2WY1 A;  2XN3 A;  1AZX I;  5BRR I;  2B4X I;  1HP7 A;  1QMB A;  2WXZ A;  3PZF A;  2OL2 A;  1K9O I;  3DLW A;  1LQ8 A;  3NDD A;  4CAA A;  1YXA A;  1R1L I;  3DRM A;  1KCT A;  3CVM A;  3DY0 A;  1TB6 I;  3T1P A;  5C98 A;  1QMN A;  3CWM A;  2R9Y A;  1E05 I;  4DY0 A;  2HI9 A;  4AQH A;  1LJ5 A;  2RIV A;  9API A;  1EZX A;  1OVA B;  2OAY A;  2CEO A;  4IC0 A;  4RO9 A;  1ANT I;  1IZ2 A;  1AS4 A;  4P0F A;  1JMO A;  1OVA C;  3EVJ I;  5HGC A;  1E04 I;  2H4P A;  1WZ9 A;  3NE4 A;  2RIW A;  1XU8 A;  1NQ9 I;  1BR8 I;  4RSQ A;  3DRU A;  1JMJ A;  2ARR A;  4Y40 A;  2ZNH A;  4R9I A;  1B3K A;  3F1S A;  2XN7 A;  1IMV A;  4GA7 A;  1OVA A;  1D5S A;  2ZV6 A;  4X30 A;  2GD4 C;  2PEE A;  4AU2 A;  7API A;  3UT3 A;  4ROA A;  1DZH L;  4ROB A;  2ARQ A;  1ATU A;  8API A;  1OYH L;  4G8O A;  3F5N A;  1F0C A;  2QUG A;  3OZQ A;  4AFX A;  3CWL A;  1JTI A;  2DUT A;  2VDX A;  3FGQ A;  3Q02 A;  1DZG L;  2ACH A;  3CAA A;  2HIJ L;  5CE0 A;  4AJT A;  2BEH L;  4C41 A;  4G8R A;  2ANT I;  1T1F A;  1OO8 A;  1OC0 A;  2PEF A;  4ZK0 A;  1SEK A;  2WXY C;  3ZHA A;  2XN6 A;  1JRR A;  4PYW A;  9PAI A;  4EB1 L;  1UHG A;  4Y3K A;  2WXX A;  3LW2 A;  4DTE A;  1DVM A;  4IF8 A;  3H5C A;  1JVQ I;  1ATH A;  5EI0 A;  2WXW A;  1DZH I;  2H4Q A;  4KDS A;  3STO A;  3NDA A;  2B4X L;  1OYH I;  3EOX A;  4BB2 A;  1ATT A;  1XQJ A;  3LE2 A;  3R4L A;  1DZG I;  1LK6 I;  3VVJ A;  1XQG A;  5CDX A;  5CDZ A;  3PB1 I;  4DY7 C;  5IO1 A;  2HIJ I;  1E03 I;  1MTP A;  1A7C A;  1JJO C;  4AU3 A;  1PSI A;  4P0O A;  2BEH I;  3Q03 A;  4AJU A;  1BY7 A;  3F02 A;  1SR5 A;  4ZK3 A;  1QLP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...