1MTPA

The x-ray crystal structure of a serpin from a thermophilic prokaryote
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
320
structure length
320
Chain Sequence
GGFLRDDHLEFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAPLLAALDRAVTDSPDLASRTVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNPEGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTREGTFRTPRGPKRVPFMHRTKTMPYATARGWRMVTLHAHDELAVDVLLPPGTNAAAVPTAPLLTALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGISTVPLYVDTVIHQARLRVDERGAEGAAATAAMMLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment
pubmed doi rcsb
molecule tags Structural genomics
source organism Thermobifida fusca
molecule keywords Serine Proteinase Inhibitor (SERPIN), Chain A
total genus 89
structure length 320
sequence length 320
ec nomenclature
pdb deposition date 2002-09-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 1mtpA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 1mtpA01
2HI9A 2XN6A 1E03I 1F0CA 7APIA 4KDSA 4C49A 1E04I 3H5CA 3CWLA 4RSQA 3EVJI 1JTIA 1OVAB 5BRRI 4DY7C 2V95A 3DRMA 1ATHA 4GA7A 3T1PA 1T1FA 1HP7A 1ATTA 4IF8A 4P0FA 2ACHA 2PEEA 4X30A 2GD4C 3DY0A 1XQGA 2CEOA 1DZHI 1IMVA 1OPHA 3NDDA 4Y40A 1JMJA 3Q02A 2R9YA 9PAIA 1XU8A 2XN3A 1OC0A 4P0OA 3LW2A 2VDXA 2ARRA 2H4QA 3R4LA 2XN5A 3UT3A 1DVMA 1OO8A 2H4PA 3B9FI 2D26A 2WY1A 2B5TI 2H4RA 3CAAA 3LE2A 1JRRA 2RIWA 5HGCA 4ZK3A 1M93B 4DTEA 5CDXA 2WY0C 2WXYC 1BY7A 4AU3B 1QLPA 4AJUA 3Q03A 1SR5A 1DB2A 3F1SA 1E05I 2WXXA 1PSIA 3NDFA 4EB1L 1JMOA 2WXZC 2VDYA 1ANTI 5INWA 4CAAA 1KCTA 3PB1I 2ANTI 1YXAA 2OAYA 4ROAA 2B4XL 2BEHL 4G8OA 4AJTA 2XN7A 4R9IA 1TB6I 3F02A 4ZK0A 2HIJI 1IZ2A 1ATUA 1B3KA 4AU3A 2ARQA 3FGQA 1K9OI 1SEKA 4EB1I 4YIAA 8APIA 1DZGI 1OYHL 3CVMA 1WZ9A 5C98A 1MTPA 1C5GA 3VVJA 4AFXA 2ZV6A 2HIJL 2B4XI 2BEHI 1JJOC 4IC0A 4DY0A 2WXZA 1QMNA 3DRUA 1DZGL 1DVNA 4AQHA 4AU4A 1AS4A 1NQ9I 3NE4A 1OVAC 1XQJA 1LQ8A 2PEFA 3NDAA 3ZHAA 2ZNHA 5EI0A 5IO1A 1C8OA 4PYWA 2QUGA 1OYHI 3EOXA 1AZXI 4AU2A 4RO9A 1D5SA 1LK6I 1QMBA 1BR8I 3F5NA 3OZQA 3PZFA 4BB2A 4ROBA 1HLEA 1JVQI 2VH4A 9APIA 1SNGA 2DUTA 5CDZA 4Y3KA 5CE0A 3KCGI 2RIVA 1EZXA 1LJ5A 2OL2A 2WXWA 4G8RA 3DLWA 4C41A 1A7CA 1R1LI 1OVAA 1UHGA 1DZHL 3STOA 3CWMA
chains in the Genus database with same CATH superfamily
2HI9A 2XN6A 1E03I 1F0CA 7APIA 4KDSA 4C49A 1E04I 3H5CA 3CWLA 4RSQA 3EVJI 1JTIA 1OVAB 5BRRI 4DY7C 2V95A 3DRMA 1ATHA 4GA7A 3T1PA 1T1FA 1HP7A 1ATTA 4IF8A 4P0FA 2ACHA 2PEEA 4X30A 2GD4C 3DY0A 1XQGA 2CEOA 1DZHI 1IMVA 1OPHA 3NDDA 4Y40A 1JMJA 3Q02A 2R9YA 9PAIA 1XU8A 2XN3A 1OC0A 4P0OA 3LW2A 2VDXA 2ARRA 2H4QA 3R4LA 2XN5A 3UT3A 1DVMA 1OO8A 2H4PA 3B9FI 2D26A 2WY1A 2B5TI 2H4RA 3CAAA 3LE2A 1JRRA 2RIWA 5HGCA 4ZK3A 1M93B 4DTEA 5CDXA 2WY0C 2WXYC 1BY7A 4AU3B 1QLPA 4AJUA 3Q03A 1SR5A 1DB2A 3F1SA 1E05I 2WXXA 1PSIA 3NDFA 4EB1L 1JMOA 2WXZC 2VDYA 1ANTI 5INWA 4CAAA 1KCTA 3PB1I 2ANTI 1YXAA 2OAYA 4ROAA 2B4XL 2BEHL 4G8OA 4AJTA 2XN7A 4R9IA 1TB6I 3F02A 4ZK0A 2HIJI 1IZ2A 1ATUA 1B3KA 4AU3A 2ARQA 3FGQA 1K9OI 1SEKA 4EB1I 4YIAA 8APIA 1DZGI 1OYHL 3CVMA 1WZ9A 5C98A 1MTPA 1C5GA 3VVJA 4AFXA 2ZV6A 2HIJL 2B4XI 2BEHI 1JJOC 4IC0A 4DY0A 2WXZA 1QMNA 3DRUA 1DZGL 1DVNA 4AQHA 4AU4A 1AS4A 1NQ9I 3NE4A 1OVAC 1XQJA 1LQ8A 2PEFA 3NDAA 3ZHAA 2ZNHA 5EI0A 5IO1A 1C8OA 4PYWA 2QUGA 1OYHI 3EOXA 1AZXI 4AU2A 4RO9A 1D5SA 1LK6I 1QMBA 1BR8I 3F5NA 3OZQA 3PZFA 4BB2A 4ROBA 1HLEA 1JVQI 2VH4A 9APIA 1SNGA 2DUTA 5CDZA 4Y3KA 5CE0A 3KCGI 2RIVA 1EZXA 1LJ5A 2OL2A 2WXWA 4G8RA 3DLWA 4C41A 1A7CA 1R1LI 1OVAA 1UHGA 1DZHL 3STOA 3CWMA
chains in the Genus database with same CATH topology
2HI9A 2XN6A 1E03I 1F0CA 7APIA 4KDSA 4C49A 1E04I 3H5CA 3CWLA 4RSQA 3EVJI 1JTIA 1OVAB 5BRRI 4DY7C 2V95A 3DRMA 1ATHA 4GA7A 3T1PA 1T1FA 1HP7A 1ATTA 4IF8A 4P0FA 2ACHA 2PEEA 4X30A 2GD4C 3DY0A 1XQGA 2CEOA 1DZHI 1IMVA 1OPHA 3NDDA 4Y40A 1JMJA 3Q02A 2R9YA 9PAIA 1XU8A 2XN3A 1OC0A 4P0OA 3LW2A 2VDXA 2ARRA 2H4QA 3R4LA 2XN5A 3UT3A 1DVMA 1OO8A 2H4PA 3B9FI 2D26A 2WY1A 2B5TI 2H4RA 3CAAA 3LE2A 1JRRA 2RIWA 5HGCA 4ZK3A 1M93B 4DTEA 5CDXA 2WY0C 2WXYC 1BY7A 4AU3B 1QLPA 4AJUA 3Q03A 1SR5A 1DB2A 3F1SA 1E05I 2WXXA 1PSIA 3NDFA 4EB1L 1JMOA 2WXZC 2VDYA 1ANTI 5INWA 4CAAA 1KCTA 3PB1I 2ANTI 1YXAA 2OAYA 4ROAA 2B4XL 2BEHL 4G8OA 4AJTA 2XN7A 4R9IA 1TB6I 3F02A 4ZK0A 2HIJI 1IZ2A 1ATUA 1B3KA 4AU3A 2ARQA 3FGQA 1K9OI 1SEKA 4EB1I 4YIAA 8APIA 1DZGI 1OYHL 3CVMA 1WZ9A 5C98A 1MTPA 1C5GA 3VVJA 4AFXA 2ZV6A 2HIJL 2B4XI 2BEHI 1JJOC 4IC0A 4DY0A 2WXZA 1QMNA 3DRUA 1DZGL 1DVNA 4AQHA 4AU4A 1AS4A 1NQ9I 3NE4A 1OVAC 1XQJA 1LQ8A 2PEFA 3NDAA 3ZHAA 2ZNHA 5EI0A 5IO1A 1C8OA 4PYWA 2QUGA 1OYHI 3EOXA 1AZXI 4AU2A 4RO9A 1D5SA 1LK6I 1QMBA 1BR8I 3F5NA 3OZQA 3PZFA 4BB2A 4ROBA 1HLEA 1JVQI 2VH4A 9APIA 1SNGA 2DUTA 5CDZA 4Y3KA 5CE0A 3KCGI 2RIVA 1EZXA 1LJ5A 2OL2A 2WXWA 4G8RA 3DLWA 4C41A 1A7CA 1R1LI 1OVAA 1UHGA 1DZHL 3STOA 3CWMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HI9 A;  2XN6 A;  1E03 I;  1F0C A;  7API A;  4KDS A;  4C49 A;  1E04 I;  3H5C A;  3CWL A;  4RSQ A;  3EVJ I;  1JTI A;  1OVA B;  5BRR I;  4DY7 C;  2V95 A;  3DRM A;  1ATH A;  4GA7 A;  3T1P A;  1T1F A;  1HP7 A;  1ATT A;  4IF8 A;  4P0F A;  2ACH A;  2PEE A;  4X30 A;  2GD4 C;  3DY0 A;  1XQG A;  2CEO A;  1DZH I;  1IMV A;  1OPH A;  3NDD A;  4Y40 A;  1JMJ A;  3Q02 A;  2R9Y A;  9PAI A;  1XU8 A;  2XN3 A;  1OC0 A;  4P0O A;  3LW2 A;  2VDX A;  2ARR A;  2H4Q A;  3R4L A;  2XN5 A;  3UT3 A;  1DVM A;  1OO8 A;  2H4P A;  3B9F I;  2D26 A;  2WY1 A;  2B5T I;  2H4R A;  3CAA A;  3LE2 A;  1JRR A;  2RIW A;  5HGC A;  4ZK3 A;  1M93 B;  4DTE A;  5CDX A;  2WY0 C;  2WXY C;  1BY7 A;  4AU3 B;  1QLP A;  4AJU A;  3Q03 A;  1SR5 A;  1DB2 A;  3F1S A;  1E05 I;  2WXX A;  1PSI A;  3NDF A;  4EB1 L;  1JMO A;  2WXZ C;  2VDY A;  1ANT I;  5INW A;  4CAA A;  1KCT A;  3PB1 I;  2ANT I;  1YXA A;  2OAY A;  4ROA A;  2B4X L;  2BEH L;  4G8O A;  4AJT A;  2XN7 A;  4R9I A;  1TB6 I;  3F02 A;  4ZK0 A;  2HIJ I;  1IZ2 A;  1ATU A;  1B3K A;  4AU3 A;  2ARQ A;  3FGQ A;  1K9O I;  1SEK A;  4EB1 I;  4YIA A;  8API A;  1DZG I;  1OYH L;  3CVM A;  1WZ9 A;  5C98 A;  1MTP A;  1C5G A;  3VVJ A;  4AFX A;  2ZV6 A;  2HIJ L;  2B4X I;  2BEH I;  1JJO C;  4IC0 A;  4DY0 A;  2WXZ A;  1QMN A;  3DRU A;  1DZG L;  1DVN A;  4AQH A;  4AU4 A;  1AS4 A;  1NQ9 I;  3NE4 A;  1OVA C;  1XQJ A;  1LQ8 A;  2PEF A;  3NDA A;  3ZHA A;  2ZNH A;  5EI0 A;  5IO1 A;  1C8O A;  4PYW A;  2QUG A;  1OYH I;  3EOX A;  1AZX I;  4AU2 A;  4RO9 A;  1D5S A;  1LK6 I;  1QMB A;  1BR8 I;  3F5N A;  3OZQ A;  3PZF A;  4BB2 A;  4ROB A;  1HLE A;  1JVQ I;  2VH4 A;  9API A;  1SNG A;  2DUT A;  5CDZ A;  4Y3K A;  5CE0 A;  3KCG I;  2RIV A;  1EZX A;  1LJ5 A;  2OL2 A;  2WXW A;  4G8R A;  3DLW A;  4C41 A;  1A7C A;  1R1L I;  1OVA A;  1UHG A;  1DZH L;  3STO A;  3CWM A; 
#chains in the Genus database with same CATH topology
 2HI9 A;  2XN6 A;  1E03 I;  1F0C A;  7API A;  4KDS A;  4C49 A;  1E04 I;  3H5C A;  3CWL A;  4RSQ A;  3EVJ I;  1JTI A;  1OVA B;  5BRR I;  4DY7 C;  2V95 A;  3DRM A;  1ATH A;  4GA7 A;  3T1P A;  1T1F A;  1HP7 A;  1ATT A;  4IF8 A;  4P0F A;  2ACH A;  2PEE A;  4X30 A;  2GD4 C;  3DY0 A;  1XQG A;  2CEO A;  1DZH I;  1IMV A;  1OPH A;  3NDD A;  4Y40 A;  1JMJ A;  3Q02 A;  2R9Y A;  9PAI A;  1XU8 A;  2XN3 A;  1OC0 A;  4P0O A;  3LW2 A;  2VDX A;  2ARR A;  2H4Q A;  3R4L A;  2XN5 A;  3UT3 A;  1DVM A;  1OO8 A;  2H4P A;  3B9F I;  2D26 A;  2WY1 A;  2B5T I;  2H4R A;  3CAA A;  3LE2 A;  1JRR A;  2RIW A;  5HGC A;  4ZK3 A;  1M93 B;  4DTE A;  5CDX A;  2WY0 C;  2WXY C;  1BY7 A;  4AU3 B;  1QLP A;  4AJU A;  3Q03 A;  1SR5 A;  1DB2 A;  3F1S A;  1E05 I;  2WXX A;  1PSI A;  3NDF A;  4EB1 L;  1JMO A;  2WXZ C;  2VDY A;  1ANT I;  5INW A;  4CAA A;  1KCT A;  3PB1 I;  2ANT I;  1YXA A;  2OAY A;  4ROA A;  2B4X L;  2BEH L;  4G8O A;  4AJT A;  2XN7 A;  4R9I A;  1TB6 I;  3F02 A;  4ZK0 A;  2HIJ I;  1IZ2 A;  1ATU A;  1B3K A;  4AU3 A;  2ARQ A;  3FGQ A;  1K9O I;  1SEK A;  4EB1 I;  4YIA A;  8API A;  1DZG I;  1OYH L;  3CVM A;  1WZ9 A;  5C98 A;  1MTP A;  1C5G A;  3VVJ A;  4AFX A;  2ZV6 A;  2HIJ L;  2B4X I;  2BEH I;  1JJO C;  4IC0 A;  4DY0 A;  2WXZ A;  1QMN A;  3DRU A;  1DZG L;  1DVN A;  4AQH A;  4AU4 A;  1AS4 A;  1NQ9 I;  3NE4 A;  1OVA C;  1XQJ A;  1LQ8 A;  2PEF A;  3NDA A;  3ZHA A;  2ZNH A;  5EI0 A;  5IO1 A;  1C8O A;  4PYW A;  2QUG A;  1OYH I;  3EOX A;  1AZX I;  4AU2 A;  4RO9 A;  1D5S A;  1LK6 I;  1QMB A;  1BR8 I;  3F5N A;  3OZQ A;  3PZF A;  4BB2 A;  4ROB A;  1HLE A;  1JVQ I;  2VH4 A;  9API A;  1SNG A;  2DUT A;  5CDZ A;  4Y3K A;  5CE0 A;  3KCG I;  2RIV A;  1EZX A;  1LJ5 A;  2OL2 A;  2WXW A;  4G8R A;  3DLW A;  4C41 A;  1A7C A;  1R1L I;  1OVA A;  1UHG A;  1DZH L;  3STO A;  3CWM A; 
#chains in the Genus database with same CATH homology
 2HI9 A;  2XN6 A;  1E03 I;  1F0C A;  7API A;  4KDS A;  4C49 A;  1E04 I;  3H5C A;  3CWL A;  4RSQ A;  3EVJ I;  1JTI A;  1OVA B;  5BRR I;  4DY7 C;  2V95 A;  3DRM A;  1ATH A;  4GA7 A;  3T1P A;  1T1F A;  1HP7 A;  1ATT A;  4IF8 A;  4P0F A;  2ACH A;  2PEE A;  4X30 A;  2GD4 C;  3DY0 A;  1XQG A;  2CEO A;  1DZH I;  1IMV A;  1OPH A;  3NDD A;  4Y40 A;  1JMJ A;  3Q02 A;  2R9Y A;  9PAI A;  1XU8 A;  2XN3 A;  1OC0 A;  4P0O A;  3LW2 A;  2VDX A;  2ARR A;  2H4Q A;  3R4L A;  2XN5 A;  3UT3 A;  1DVM A;  1OO8 A;  2H4P A;  3B9F I;  2D26 A;  2WY1 A;  2B5T I;  2H4R A;  3CAA A;  3LE2 A;  1JRR A;  2RIW A;  5HGC A;  4ZK3 A;  1M93 B;  4DTE A;  5CDX A;  2WY0 C;  2WXY C;  1BY7 A;  4AU3 B;  1QLP A;  4AJU A;  3Q03 A;  1SR5 A;  1DB2 A;  3F1S A;  1E05 I;  2WXX A;  1PSI A;  3NDF A;  4EB1 L;  1JMO A;  2WXZ C;  2VDY A;  1ANT I;  5INW A;  4CAA A;  1KCT A;  3PB1 I;  2ANT I;  1YXA A;  2OAY A;  4ROA A;  2B4X L;  2BEH L;  4G8O A;  4AJT A;  2XN7 A;  4R9I A;  1TB6 I;  3F02 A;  4ZK0 A;  2HIJ I;  1IZ2 A;  1ATU A;  1B3K A;  4AU3 A;  2ARQ A;  3FGQ A;  1K9O I;  1SEK A;  4EB1 I;  4YIA A;  8API A;  1DZG I;  1OYH L;  3CVM A;  1WZ9 A;  5C98 A;  1MTP A;  1C5G A;  3VVJ A;  4AFX A;  2ZV6 A;  2HIJ L;  2B4X I;  2BEH I;  1JJO C;  4IC0 A;  4DY0 A;  2WXZ A;  1QMN A;  3DRU A;  1DZG L;  1DVN A;  4AQH A;  4AU4 A;  1AS4 A;  1NQ9 I;  3NE4 A;  1OVA C;  1XQJ A;  1LQ8 A;  2PEF A;  3NDA A;  3ZHA A;  2ZNH A;  5EI0 A;  5IO1 A;  1C8O A;  4PYW A;  2QUG A;  1OYH I;  3EOX A;  1AZX I;  4AU2 A;  4RO9 A;  1D5S A;  1LK6 I;  1QMB A;  1BR8 I;  3F5N A;  3OZQ A;  3PZF A;  4BB2 A;  4ROB A;  1HLE A;  1JVQ I;  2VH4 A;  9API A;  1SNG A;  2DUT A;  5CDZ A;  4Y3K A;  5CE0 A;  3KCG I;  2RIV A;  1EZX A;  1LJ5 A;  2OL2 A;  2WXW A;  4G8R A;  3DLW A;  4C41 A;  1A7C A;  1R1L I;  1OVA A;  1UHG A;  1DZH L;  3STO A;  3CWM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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