1XQGA

3.10 a crystal structure of maspin, space group p 4 21 2
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
378
structure length
378
Chain Sequence
QGSMDALQLANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKESPFRVNKTDTKPVQMMNMEATFSMGNIDSINSKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKASLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVSLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFSSP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Human Maspin, a Serpin with Antitumor Properties: Reactive Center Loop of Mapsin is Exposed but Constrained
pubmed doi rcsb
molecule tags Antitumor protein
source organism Homo sapiens
molecule keywords Maspin
total genus 116
structure length 378
sequence length 378
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 1xqgA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 1xqgA01
2B5TI 4AJUA 2XN6A 3LE2A 1OYHI 1IMVA 5IO1A 4BB2A 1XQGA 1B3KA 5HGCA 2ANTI 1DB2A 1WZ9A 3NDAA 2ZNHA 3R4LA 3B9FI 4AJTA 3F1SA 9APIA 1ATUA 1K9OI 1AZXI 2XN7A 4PYWA 4Y3KA 3STOA 3NDDA 1HP7A 3ZHAA 3PZFA 1NQ9I 1OC0A 4AU3B 2HI9A 5CE0A 1EZXA 4AQHA 7APIA 1ATHA 4ZK3A 3NE4A 2QUGA 2VH4A 4EB1I 2BEHL 4G8RA 2PEEA 4YIAA 2VDXA 3DY0A 1QMBA 1QMNA 4C49A 2XN5A 4DTEA 3OZQA 2R9YA 3CWLA 2HIJL 1BR8I 1KCTA 3NDFA 5CDZA 3EOXA 1DZGI 2GD4C 1JVQI 1ATTA 1XU8A 1JMOA 1OYHL 2WXXA 3LW2A 4CAAA 4ZK0A 5INWA 1E05I 3CVMA 3UT3A 2H4QA 4AU3A 1JMJA 1DVMA 2CEOA 2WY1A 1C5GA 4G8OA 4Y40A 3CWMA 2OL2A 2XN3A 2WXZC 1DVNA 1XQJA 1YXAA 1SEKA 5BRRI 4IF8A 3CAAA 1JTIA 1A7CA 1DZHI 3T1PA 4EB1L 1QLPA 1AS4A 3DLWA 9PAIA 1F0CA 1HLEA 2WXZA 4P0FA 2DUTA 4ROAA 4AU2A 4P0OA 2WY0C 2ARRA 2D26A 1DZGL 4X30A 4RSQA 2RIVA 2VDYA 1M93B 4R9IA 1LJ5A 3EVJI 1T1FA 1TB6I 4AFXA 1R1LI 1D5SA 1OVAB 3DRUA 3Q02A 2B4XI 1PSIA 2ARQA 2RIWA 3Q03A 3F02A 2WXYC 2B4XL 3PB1I 1E03I 8APIA 3H5CA 2H4PA 2V95A 2WXWA 1MTPA 2OAYA 3VVJA 3KCGI 3DRMA 4IC0A 1ANTI 4ROBA 1OVAC 1DZHL 2PEFA 1LK6I 4GA7A 2H4RA 4C41A 2ACHA 4DY7C 4KDSA 4AU4A 1OO8A 1JRRA 1OPHA 1OVAA 1LQ8A 3F5NA 4DY0A 5C98A 5CDXA 1C8OA 1JJOC 2BEHI 4RO9A 1SNGA 1SR5A 1BY7A 1IZ2A 3FGQA 1E04I 1UHGA 2ZV6A 5EI0A 2HIJI
chains in the Genus database with same CATH superfamily
2B5TI 4AJUA 2XN6A 3LE2A 1OYHI 1IMVA 5IO1A 4BB2A 1XQGA 1B3KA 5HGCA 2ANTI 1DB2A 1WZ9A 3NDAA 2ZNHA 3R4LA 3B9FI 4AJTA 3F1SA 9APIA 1ATUA 1K9OI 1AZXI 2XN7A 4PYWA 4Y3KA 3STOA 3NDDA 1HP7A 3ZHAA 3PZFA 1NQ9I 1OC0A 4AU3B 2HI9A 5CE0A 1EZXA 4AQHA 7APIA 1ATHA 4ZK3A 3NE4A 2QUGA 2VH4A 4EB1I 2BEHL 4G8RA 2PEEA 4YIAA 2VDXA 3DY0A 1QMBA 1QMNA 4C49A 2XN5A 4DTEA 3OZQA 2R9YA 3CWLA 2HIJL 1BR8I 1KCTA 3NDFA 5CDZA 3EOXA 1DZGI 2GD4C 1JVQI 1ATTA 1XU8A 1JMOA 1OYHL 2WXXA 3LW2A 4CAAA 4ZK0A 5INWA 1E05I 3CVMA 3UT3A 2H4QA 4AU3A 1JMJA 1DVMA 2CEOA 2WY1A 1C5GA 4G8OA 4Y40A 3CWMA 2OL2A 2XN3A 2WXZC 1DVNA 1XQJA 1YXAA 1SEKA 5BRRI 4IF8A 3CAAA 1JTIA 1A7CA 1DZHI 3T1PA 4EB1L 1QLPA 1AS4A 3DLWA 9PAIA 1F0CA 1HLEA 2WXZA 4P0FA 2DUTA 4ROAA 4AU2A 4P0OA 2WY0C 2ARRA 2D26A 1DZGL 4X30A 4RSQA 2RIVA 2VDYA 1M93B 4R9IA 1LJ5A 3EVJI 1T1FA 1TB6I 4AFXA 1R1LI 1D5SA 1OVAB 3DRUA 3Q02A 2B4XI 1PSIA 2ARQA 2RIWA 3Q03A 3F02A 2WXYC 2B4XL 3PB1I 1E03I 8APIA 3H5CA 2H4PA 2V95A 2WXWA 1MTPA 2OAYA 3VVJA 3KCGI 3DRMA 4IC0A 1ANTI 4ROBA 1OVAC 1DZHL 2PEFA 1LK6I 4GA7A 2H4RA 4C41A 2ACHA 4DY7C 4KDSA 4AU4A 1OO8A 1JRRA 1OPHA 1OVAA 1LQ8A 3F5NA 4DY0A 5C98A 5CDXA 1C8OA 1JJOC 2BEHI 4RO9A 1SNGA 1SR5A 1BY7A 1IZ2A 3FGQA 1E04I 1UHGA 2ZV6A 5EI0A 2HIJI
chains in the Genus database with same CATH topology
2B5TI 4AJUA 2XN6A 3LE2A 1OYHI 1IMVA 5IO1A 4BB2A 1XQGA 1B3KA 5HGCA 2ANTI 1DB2A 1WZ9A 3NDAA 2ZNHA 3R4LA 3B9FI 4AJTA 3F1SA 9APIA 1ATUA 1K9OI 1AZXI 2XN7A 4PYWA 4Y3KA 3STOA 3NDDA 1HP7A 3ZHAA 3PZFA 1NQ9I 1OC0A 4AU3B 2HI9A 5CE0A 1EZXA 4AQHA 7APIA 1ATHA 4ZK3A 3NE4A 2QUGA 2VH4A 4EB1I 2BEHL 4G8RA 2PEEA 4YIAA 2VDXA 3DY0A 1QMBA 1QMNA 4C49A 2XN5A 4DTEA 3OZQA 2R9YA 3CWLA 2HIJL 1BR8I 1KCTA 3NDFA 5CDZA 3EOXA 1DZGI 2GD4C 1JVQI 1ATTA 1XU8A 1JMOA 1OYHL 2WXXA 3LW2A 4CAAA 4ZK0A 5INWA 1E05I 3CVMA 3UT3A 2H4QA 4AU3A 1JMJA 1DVMA 2CEOA 2WY1A 1C5GA 4G8OA 4Y40A 3CWMA 2OL2A 2XN3A 2WXZC 1DVNA 1XQJA 1YXAA 1SEKA 5BRRI 4IF8A 3CAAA 1JTIA 1A7CA 1DZHI 3T1PA 4EB1L 1QLPA 1AS4A 3DLWA 9PAIA 1F0CA 1HLEA 2WXZA 4P0FA 2DUTA 4ROAA 4AU2A 4P0OA 2WY0C 2ARRA 2D26A 1DZGL 4X30A 4RSQA 2RIVA 2VDYA 1M93B 4R9IA 1LJ5A 3EVJI 1T1FA 1TB6I 4AFXA 1R1LI 1D5SA 1OVAB 3DRUA 3Q02A 2B4XI 1PSIA 2ARQA 2RIWA 3Q03A 3F02A 2WXYC 2B4XL 3PB1I 1E03I 8APIA 3H5CA 2H4PA 2V95A 2WXWA 1MTPA 2OAYA 3VVJA 3KCGI 3DRMA 4IC0A 1ANTI 4ROBA 1OVAC 1DZHL 2PEFA 1LK6I 4GA7A 2H4RA 4C41A 2ACHA 4DY7C 4KDSA 4AU4A 1OO8A 1JRRA 1OPHA 1OVAA 1LQ8A 3F5NA 4DY0A 5C98A 5CDXA 1C8OA 1JJOC 2BEHI 4RO9A 1SNGA 1SR5A 1BY7A 1IZ2A 3FGQA 1E04I 1UHGA 2ZV6A 5EI0A 2HIJI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2B5T I;  4AJU A;  2XN6 A;  3LE2 A;  1OYH I;  1IMV A;  5IO1 A;  4BB2 A;  1XQG A;  1B3K A;  5HGC A;  2ANT I;  1DB2 A;  1WZ9 A;  3NDA A;  2ZNH A;  3R4L A;  3B9F I;  4AJT A;  3F1S A;  9API A;  1ATU A;  1K9O I;  1AZX I;  2XN7 A;  4PYW A;  4Y3K A;  3STO A;  3NDD A;  1HP7 A;  3ZHA A;  3PZF A;  1NQ9 I;  1OC0 A;  4AU3 B;  2HI9 A;  5CE0 A;  1EZX A;  4AQH A;  7API A;  1ATH A;  4ZK3 A;  3NE4 A;  2QUG A;  2VH4 A;  4EB1 I;  2BEH L;  4G8R A;  2PEE A;  4YIA A;  2VDX A;  3DY0 A;  1QMB A;  1QMN A;  4C49 A;  2XN5 A;  4DTE A;  3OZQ A;  2R9Y A;  3CWL A;  2HIJ L;  1BR8 I;  1KCT A;  3NDF A;  5CDZ A;  3EOX A;  1DZG I;  2GD4 C;  1JVQ I;  1ATT A;  1XU8 A;  1JMO A;  1OYH L;  2WXX A;  3LW2 A;  4CAA A;  4ZK0 A;  5INW A;  1E05 I;  3CVM A;  3UT3 A;  2H4Q A;  4AU3 A;  1JMJ A;  1DVM A;  2CEO A;  2WY1 A;  1C5G A;  4G8O A;  4Y40 A;  3CWM A;  2OL2 A;  2XN3 A;  2WXZ C;  1DVN A;  1XQJ A;  1YXA A;  1SEK A;  5BRR I;  4IF8 A;  3CAA A;  1JTI A;  1A7C A;  1DZH I;  3T1P A;  4EB1 L;  1QLP A;  1AS4 A;  3DLW A;  9PAI A;  1F0C A;  1HLE A;  2WXZ A;  4P0F A;  2DUT A;  4ROA A;  4AU2 A;  4P0O A;  2WY0 C;  2ARR A;  2D26 A;  1DZG L;  4X30 A;  4RSQ A;  2RIV A;  2VDY A;  1M93 B;  4R9I A;  1LJ5 A;  3EVJ I;  1T1F A;  1TB6 I;  4AFX A;  1R1L I;  1D5S A;  1OVA B;  3DRU A;  3Q02 A;  2B4X I;  1PSI A;  2ARQ A;  2RIW A;  3Q03 A;  3F02 A;  2WXY C;  2B4X L;  3PB1 I;  1E03 I;  8API A;  3H5C A;  2H4P A;  2V95 A;  2WXW A;  1MTP A;  2OAY A;  3VVJ A;  3KCG I;  3DRM A;  4IC0 A;  1ANT I;  4ROB A;  1OVA C;  1DZH L;  2PEF A;  1LK6 I;  4GA7 A;  2H4R A;  4C41 A;  2ACH A;  4DY7 C;  4KDS A;  4AU4 A;  1OO8 A;  1JRR A;  1OPH A;  1OVA A;  1LQ8 A;  3F5N A;  4DY0 A;  5C98 A;  5CDX A;  1C8O A;  1JJO C;  2BEH I;  4RO9 A;  1SNG A;  1SR5 A;  1BY7 A;  1IZ2 A;  3FGQ A;  1E04 I;  1UHG A;  2ZV6 A;  5EI0 A;  2HIJ I; 
#chains in the Genus database with same CATH topology
 2B5T I;  4AJU A;  2XN6 A;  3LE2 A;  1OYH I;  1IMV A;  5IO1 A;  4BB2 A;  1XQG A;  1B3K A;  5HGC A;  2ANT I;  1DB2 A;  1WZ9 A;  3NDA A;  2ZNH A;  3R4L A;  3B9F I;  4AJT A;  3F1S A;  9API A;  1ATU A;  1K9O I;  1AZX I;  2XN7 A;  4PYW A;  4Y3K A;  3STO A;  3NDD A;  1HP7 A;  3ZHA A;  3PZF A;  1NQ9 I;  1OC0 A;  4AU3 B;  2HI9 A;  5CE0 A;  1EZX A;  4AQH A;  7API A;  1ATH A;  4ZK3 A;  3NE4 A;  2QUG A;  2VH4 A;  4EB1 I;  2BEH L;  4G8R A;  2PEE A;  4YIA A;  2VDX A;  3DY0 A;  1QMB A;  1QMN A;  4C49 A;  2XN5 A;  4DTE A;  3OZQ A;  2R9Y A;  3CWL A;  2HIJ L;  1BR8 I;  1KCT A;  3NDF A;  5CDZ A;  3EOX A;  1DZG I;  2GD4 C;  1JVQ I;  1ATT A;  1XU8 A;  1JMO A;  1OYH L;  2WXX A;  3LW2 A;  4CAA A;  4ZK0 A;  5INW A;  1E05 I;  3CVM A;  3UT3 A;  2H4Q A;  4AU3 A;  1JMJ A;  1DVM A;  2CEO A;  2WY1 A;  1C5G A;  4G8O A;  4Y40 A;  3CWM A;  2OL2 A;  2XN3 A;  2WXZ C;  1DVN A;  1XQJ A;  1YXA A;  1SEK A;  5BRR I;  4IF8 A;  3CAA A;  1JTI A;  1A7C A;  1DZH I;  3T1P A;  4EB1 L;  1QLP A;  1AS4 A;  3DLW A;  9PAI A;  1F0C A;  1HLE A;  2WXZ A;  4P0F A;  2DUT A;  4ROA A;  4AU2 A;  4P0O A;  2WY0 C;  2ARR A;  2D26 A;  1DZG L;  4X30 A;  4RSQ A;  2RIV A;  2VDY A;  1M93 B;  4R9I A;  1LJ5 A;  3EVJ I;  1T1F A;  1TB6 I;  4AFX A;  1R1L I;  1D5S A;  1OVA B;  3DRU A;  3Q02 A;  2B4X I;  1PSI A;  2ARQ A;  2RIW A;  3Q03 A;  3F02 A;  2WXY C;  2B4X L;  3PB1 I;  1E03 I;  8API A;  3H5C A;  2H4P A;  2V95 A;  2WXW A;  1MTP A;  2OAY A;  3VVJ A;  3KCG I;  3DRM A;  4IC0 A;  1ANT I;  4ROB A;  1OVA C;  1DZH L;  2PEF A;  1LK6 I;  4GA7 A;  2H4R A;  4C41 A;  2ACH A;  4DY7 C;  4KDS A;  4AU4 A;  1OO8 A;  1JRR A;  1OPH A;  1OVA A;  1LQ8 A;  3F5N A;  4DY0 A;  5C98 A;  5CDX A;  1C8O A;  1JJO C;  2BEH I;  4RO9 A;  1SNG A;  1SR5 A;  1BY7 A;  1IZ2 A;  3FGQ A;  1E04 I;  1UHG A;  2ZV6 A;  5EI0 A;  2HIJ I; 
#chains in the Genus database with same CATH homology
 2B5T I;  4AJU A;  2XN6 A;  3LE2 A;  1OYH I;  1IMV A;  5IO1 A;  4BB2 A;  1XQG A;  1B3K A;  5HGC A;  2ANT I;  1DB2 A;  1WZ9 A;  3NDA A;  2ZNH A;  3R4L A;  3B9F I;  4AJT A;  3F1S A;  9API A;  1ATU A;  1K9O I;  1AZX I;  2XN7 A;  4PYW A;  4Y3K A;  3STO A;  3NDD A;  1HP7 A;  3ZHA A;  3PZF A;  1NQ9 I;  1OC0 A;  4AU3 B;  2HI9 A;  5CE0 A;  1EZX A;  4AQH A;  7API A;  1ATH A;  4ZK3 A;  3NE4 A;  2QUG A;  2VH4 A;  4EB1 I;  2BEH L;  4G8R A;  2PEE A;  4YIA A;  2VDX A;  3DY0 A;  1QMB A;  1QMN A;  4C49 A;  2XN5 A;  4DTE A;  3OZQ A;  2R9Y A;  3CWL A;  2HIJ L;  1BR8 I;  1KCT A;  3NDF A;  5CDZ A;  3EOX A;  1DZG I;  2GD4 C;  1JVQ I;  1ATT A;  1XU8 A;  1JMO A;  1OYH L;  2WXX A;  3LW2 A;  4CAA A;  4ZK0 A;  5INW A;  1E05 I;  3CVM A;  3UT3 A;  2H4Q A;  4AU3 A;  1JMJ A;  1DVM A;  2CEO A;  2WY1 A;  1C5G A;  4G8O A;  4Y40 A;  3CWM A;  2OL2 A;  2XN3 A;  2WXZ C;  1DVN A;  1XQJ A;  1YXA A;  1SEK A;  5BRR I;  4IF8 A;  3CAA A;  1JTI A;  1A7C A;  1DZH I;  3T1P A;  4EB1 L;  1QLP A;  1AS4 A;  3DLW A;  9PAI A;  1F0C A;  1HLE A;  2WXZ A;  4P0F A;  2DUT A;  4ROA A;  4AU2 A;  4P0O A;  2WY0 C;  2ARR A;  2D26 A;  1DZG L;  4X30 A;  4RSQ A;  2RIV A;  2VDY A;  1M93 B;  4R9I A;  1LJ5 A;  3EVJ I;  1T1F A;  1TB6 I;  4AFX A;  1R1L I;  1D5S A;  1OVA B;  3DRU A;  3Q02 A;  2B4X I;  1PSI A;  2ARQ A;  2RIW A;  3Q03 A;  3F02 A;  2WXY C;  2B4X L;  3PB1 I;  1E03 I;  8API A;  3H5C A;  2H4P A;  2V95 A;  2WXW A;  1MTP A;  2OAY A;  3VVJ A;  3KCG I;  3DRM A;  4IC0 A;  1ANT I;  4ROB A;  1OVA C;  1DZH L;  2PEF A;  1LK6 I;  4GA7 A;  2H4R A;  4C41 A;  2ACH A;  4DY7 C;  4KDS A;  4AU4 A;  1OO8 A;  1JRR A;  1OPH A;  1OVA A;  1LQ8 A;  3F5N A;  4DY0 A;  5C98 A;  5CDX A;  1C8O A;  1JJO C;  2BEH I;  4RO9 A;  1SNG A;  1SR5 A;  1BY7 A;  1IZ2 A;  3FGQ A;  1E04 I;  1UHG A;  2ZV6 A;  5EI0 A;  2HIJ I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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