The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
93
|
sequence length |
337
|
structure length |
337
|
Chain Sequence |
LGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLL
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins.
pubmed doi rcsb |
| molecule tags |
Proteinase inhibitor
|
| source organism |
Homo sapiens
|
| molecule keywords |
ALPHA 1-ANTICHYMOTRYPSIN
|
| total genus |
93
|
| structure length |
337
|
| sequence length |
337
|
| ec nomenclature | |
| pdb deposition date | 1993-04-26 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Roll | Alpha-1-antitrypsin; domain 1 | Alpha-1-antitrypsin, domain 1 | ||
| Alpha Beta | 2-Layer Sandwich | Antithrombin; Chain I, domain 2 | Antithrombin, subunit I, domain 2 |
#chains in the Genus database with same CATH superfamily 3NDA A; 2H4P A; 3EVJ I; 2BEH I; 4DY0 A; 9API A; 1C8O A; 2ARR A; 1JRR A; 2PEE A; 4X30 A; 4DY7 C; 3PZF A; 1DZG I; 2HIJ L; 8API A; 2XN3 A; 2XN7 A; 1D5S A; 1EZX A; 2B4X I; 1LK6 I; 2XN5 A; 1HLE A; 1BY7 A; 1OVA A; 3FGQ A; 1BR8 I; 1JMJ A; 1XQG A; 1SR5 A; 2WXZ C; 2WXW A; 3DLW A; 4Y40 A; 3STO A; 4AJT A; 3LW2 A; 1ATT A; 4G8O A; 5BRR I; 1QMN A; 5CDX A; 1JTI A; 5CE0 A; 1OC0 A; 2GD4 C; 3OZQ A; 3T1P A; 1OVA B; 2VDY A; 3H5C A; 5CDZ A; 3Q02 A; 2VDX A; 3VVJ A; 3EOX A; 2ZNH A; 1SEK A; 1DVM A; 1JJO C; 1AS4 A; 1KCT A; 2WXY C; 1NQ9 I; 2ARQ A; 2HIJ I; 3DRU A; 4P0F A; 4BB2 A; 4DTE A; 1QLP A; 1DZH L; 4AU3 A; 1JMO A; 1QMB A; 3NDF A; 1PSI A; 1SNG A; 3NDD A; 4Y3K A; 5HGC A; 4AU3 B; 4AU2 A; 3CWM A; 4G8R A; 1R1L I; 4IF8 A; 1HP7 A; 2CEO A; 1YXA A; 4ZK3 A; 4RSQ A; 4AFX A; 2OAY A; 1OPH A; 1OO8 A; 4PYW A; 1OYH L; 2WY1 A; 4EB1 L; 1C5G A; 4ROA A; 1ATH A; 3ZHA A; 1XQJ A; 1AZX I; 4GA7 A; 2XN6 A; 3Q03 A; 1OVA C; 2PEF A; 3NE4 A; 3F5N A; 2RIW A; 1DZH I; 2D26 A; 4C49 A; 5INW A; 1XU8 A; 3CWL A; 2HI9 A; 1B3K A; 3PB1 I; 3F1S A; 4AQH A; 1E05 I; 3F02 A; 1WZ9 A; 2WY0 C; 4CAA A; 1JVQ I; 1K9O I; 2OL2 A; 9PAI A; 4R9I A; 2H4Q A; 1E03 I; 1M93 B; 1OYH I; 3DRM A; 4EB1 I; 1IMV A; 1DVN A; 3KCG I; 2WXZ A; 4P0O A; 2DUT A; 4IC0 A; 2QUG A; 4AJU A; 7API A; 2V95 A; 2BEH L; 2ZV6 A; 4ZK0 A; 1TB6 I; 2ACH A; 1LQ8 A; 1T1F A; 2ANT I; 2WXX A; 2R9Y A; 1DZG L; 2H4R A; 3DY0 A; 1A7C A; 1E04 I; 1MTP A; 2B4X L; 3LE2 A; 1DB2 A; 4ROB A; 3CVM A; 4RO9 A; 2B5T I; 2VH4 A; 1IZ2 A; 1UHG A; 3R4L A; 4YIA A; 5EI0 A; 3B9F I; 1LJ5 A; 1ATU A; 4C41 A; 1F0C A; 1ANT I; 3CAA A; 5C98 A; 3UT3 A; 5IO1 A; 4KDS A; 4AU4 A; 2RIV A; #chains in the Genus database with same CATH topology 3NDA A; 2H4P A; 3EVJ I; 2BEH I; 4DY0 A; 9API A; 1C8O A; 2ARR A; 1JRR A; 2PEE A; 4X30 A; 4DY7 C; 3PZF A; 1DZG I; 2HIJ L; 8API A; 2XN3 A; 2XN7 A; 1D5S A; 1EZX A; 2B4X I; 1LK6 I; 2XN5 A; 1HLE A; 1BY7 A; 1OVA A; 3FGQ A; 1BR8 I; 1JMJ A; 1XQG A; 1SR5 A; 2WXZ C; 2WXW A; 3DLW A; 4Y40 A; 3STO A; 4AJT A; 3LW2 A; 1ATT A; 4G8O A; 5BRR I; 1QMN A; 5CDX A; 1JTI A; 5CE0 A; 1OC0 A; 2GD4 C; 3OZQ A; 3T1P A; 1OVA B; 2VDY A; 3H5C A; 5CDZ A; 3Q02 A; 2VDX A; 3VVJ A; 3EOX A; 2ZNH A; 1SEK A; 1DVM A; 1JJO C; 1AS4 A; 1KCT A; 2WXY C; 1NQ9 I; 2ARQ A; 2HIJ I; 3DRU A; 4P0F A; 4BB2 A; 4DTE A; 1QLP A; 1DZH L; 4AU3 A; 1JMO A; 1QMB A; 3NDF A; 1PSI A; 1SNG A; 3NDD A; 4Y3K A; 5HGC A; 4AU3 B; 4AU2 A; 3CWM A; 4G8R A; 1R1L I; 4IF8 A; 1HP7 A; 2CEO A; 1YXA A; 4ZK3 A; 4RSQ A; 4AFX A; 2OAY A; 1OPH A; 1OO8 A; 4PYW A; 1OYH L; 2WY1 A; 4EB1 L; 1C5G A; 4ROA A; 1ATH A; 3ZHA A; 1XQJ A; 1AZX I; 4GA7 A; 2XN6 A; 3Q03 A; 1OVA C; 2PEF A; 3NE4 A; 3F5N A; 2RIW A; 1DZH I; 2D26 A; 4C49 A; 5INW A; 1XU8 A; 3CWL A; 2HI9 A; 1B3K A; 3PB1 I; 3F1S A; 4AQH A; 1E05 I; 3F02 A; 1WZ9 A; 2WY0 C; 4CAA A; 1JVQ I; 1K9O I; 2OL2 A; 9PAI A; 4R9I A; 2H4Q A; 1E03 I; 1M93 B; 1OYH I; 3DRM A; 4EB1 I; 1IMV A; 1DVN A; 3KCG I; 2WXZ A; 4P0O A; 2DUT A; 4IC0 A; 2QUG A; 4AJU A; 7API A; 2V95 A; 2BEH L; 2ZV6 A; 4ZK0 A; 1TB6 I; 2ACH A; 1LQ8 A; 1T1F A; 2ANT I; 2WXX A; 2R9Y A; 1DZG L; 2H4R A; 3DY0 A; 1A7C A; 1E04 I; 1MTP A; 2B4X L; 3LE2 A; 1DB2 A; 4ROB A; 3CVM A; 4RO9 A; 2B5T I; 2VH4 A; 1IZ2 A; 1UHG A; 3R4L A; 4YIA A; 5EI0 A; 3B9F I; 1LJ5 A; 1ATU A; 4C41 A; 1F0C A; 1ANT I; 3CAA A; 5C98 A; 3UT3 A; 5IO1 A; 4KDS A; 4AU4 A; 2RIV A; #chains in the Genus database with same CATH homology 3NDA A; 2H4P A; 3EVJ I; 2BEH I; 4DY0 A; 9API A; 1C8O A; 2ARR A; 1JRR A; 2PEE A; 4X30 A; 4DY7 C; 3PZF A; 1DZG I; 2HIJ L; 8API A; 2XN3 A; 2XN7 A; 1D5S A; 1EZX A; 2B4X I; 1LK6 I; 2XN5 A; 1HLE A; 1BY7 A; 1OVA A; 3FGQ A; 1BR8 I; 1JMJ A; 1XQG A; 1SR5 A; 2WXZ C; 2WXW A; 3DLW A; 4Y40 A; 3STO A; 4AJT A; 3LW2 A; 1ATT A; 4G8O A; 5BRR I; 1QMN A; 5CDX A; 1JTI A; 5CE0 A; 1OC0 A; 2GD4 C; 3OZQ A; 3T1P A; 1OVA B; 2VDY A; 3H5C A; 5CDZ A; 3Q02 A; 2VDX A; 3VVJ A; 3EOX A; 2ZNH A; 1SEK A; 1DVM A; 1JJO C; 1AS4 A; 1KCT A; 2WXY C; 1NQ9 I; 2ARQ A; 2HIJ I; 3DRU A; 4P0F A; 4BB2 A; 4DTE A; 1QLP A; 1DZH L; 4AU3 A; 1JMO A; 1QMB A; 3NDF A; 1PSI A; 1SNG A; 3NDD A; 4Y3K A; 5HGC A; 4AU3 B; 4AU2 A; 3CWM A; 4G8R A; 1R1L I; 4IF8 A; 1HP7 A; 2CEO A; 1YXA A; 4ZK3 A; 4RSQ A; 4AFX A; 2OAY A; 1OPH A; 1OO8 A; 4PYW A; 1OYH L; 2WY1 A; 4EB1 L; 1C5G A; 4ROA A; 1ATH A; 3ZHA A; 1XQJ A; 1AZX I; 4GA7 A; 2XN6 A; 3Q03 A; 1OVA C; 2PEF A; 3NE4 A; 3F5N A; 2RIW A; 1DZH I; 2D26 A; 4C49 A; 5INW A; 1XU8 A; 3CWL A; 2HI9 A; 1B3K A; 3PB1 I; 3F1S A; 4AQH A; 1E05 I; 3F02 A; 1WZ9 A; 2WY0 C; 4CAA A; 1JVQ I; 1K9O I; 2OL2 A; 9PAI A; 4R9I A; 2H4Q A; 1E03 I; 1M93 B; 1OYH I; 3DRM A; 4EB1 I; 1IMV A; 1DVN A; 3KCG I; 2WXZ A; 4P0O A; 2DUT A; 4IC0 A; 2QUG A; 4AJU A; 7API A; 2V95 A; 2BEH L; 2ZV6 A; 4ZK0 A; 1TB6 I; 2ACH A; 1LQ8 A; 1T1F A; 2ANT I; 2WXX A; 2R9Y A; 1DZG L; 2H4R A; 3DY0 A; 1A7C A; 1E04 I; 1MTP A; 2B4X L; 3LE2 A; 1DB2 A; 4ROB A; 3CVM A; 4RO9 A; 2B5T I; 2VH4 A; 1IZ2 A; 1UHG A; 3R4L A; 4YIA A; 5EI0 A; 3B9F I; 1LJ5 A; 1ATU A; 4C41 A; 1F0C A; 1ANT I; 3CAA A; 5C98 A; 3UT3 A; 5IO1 A; 4KDS A; 4AU4 A; 2RIV A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
