2HIJL

Crystal structure of p14 alanine variant of antithrombin
Total Genus 111
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
426
structure length
409
Chain Sequence
VDICTAKPRDIPMNPMCIYRSPATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTKANRPFLVFIREVPLNTIIFMGRVANPC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal Structure of P14 Alanine Variant of Antithrombin
rcsb
molecule tags Blood clotting/ hydrolase inhibitor
source organism Homo sapiens
molecule keywords Antithrombin-III
total genus 111
structure length 409
sequence length 426
ec nomenclature
pdb deposition date 2006-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2hijL02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2hijL01
1B3KA 5IO1A 3T1PA 1XQJA 3Q03A 1QMNA 1M93B 3STOA 1DVMA 1E05I 3FGQA 3NDFA 1OVAB 2WXXA 4YIAA 7APIA 2ACHA 4Y40A 4IC0A 4DY7C 1OO8A 2DUTA 2HIJI 1ATUA 3B9FI 2PEFA 2H4PA 2ZNHA 2ANTI 4ZK3A 2WY0C 5EI0A 1E03I 2XN6A 4AQHA 4G8RA 5HGCA 1DZHL 4AU3B 1AS4A 1MTPA 1KCTA 2ARQA 2PEEA 1JMOA 1LQ8A 3R4LA 3CWMA 2D26A 3CAAA 3DY0A 2VDYA 1OPHA 9APIA 8APIA 1XU8A 4AJTA 1OYHL 5CDZA 3CWLA 1OVAA 2RIWA 4RSQA 2WXWA 2GD4C 4ROAA 4IF8A 4RO9A 1IZ2A 3ZHAA 1QMBA 2XN3A 5CE0A 3KCGI 1DZGL 1OC0A 1QLPA 4BB2A 1NQ9I 4DTEA 4AU4A 5BRRI 1TB6I 2VDXA 3EVJI 1BY7A 1ATHA 2RIVA 1JJOC 1OVAC 1F0CA 1YXAA 3NDDA 2BEHI 4AU3A 4C49A 2B5TI 3DLWA 4R9IA 2V95A 9PAIA 3Q02A 1JVQI 4CAAA 1K9OI 2HIJL 4C41A 2B4XL 1EZXA 1BR8I 4P0FA 2VH4A 5INWA 2H4RA 4EB1L 2HI9A 2XN5A 1DB2A 4KDSA 1XQGA 2WXYC 1HLEA 1LJ5A 1JMJA 3F02A 3LW2A 2ARRA 4G8OA 4ZK0A 2WY1A 2ZV6A 3F5NA 3H5CA 3PZFA 1HP7A 2QUGA 4X30A 2XN7A 1AZXI 1ATTA 4AU2A 2WXZA 5CDXA 1SR5A 1A7CA 1ANTI 1PSIA 2H4QA 3UT3A 4P0OA 3VVJA 1DVNA 1DZHI 3DRMA 1JTIA 3OZQA 3F1SA 2OAYA 4Y3KA 1SNGA 3NE4A 1WZ9A 4ROBA 2R9YA 3CVMA 1UHGA 2B4XI 3EOXA 1LK6I 2WXZC 4GA7A 1D5SA 1JRRA 1R1LI 5C98A 3NDAA 1OYHI 2BEHL 3LE2A 4PYWA 4EB1I 1C5GA 3DRUA 1C8OA 1E04I 1T1FA 4AJUA 4DY0A 4AFXA 2CEOA 2OL2A 3PB1I 1IMVA 1DZGI 1SEKA
chains in the Genus database with same CATH superfamily
1B3KA 5IO1A 3T1PA 1XQJA 3Q03A 1QMNA 1M93B 3STOA 1DVMA 1E05I 3FGQA 3NDFA 1OVAB 2WXXA 4YIAA 7APIA 2ACHA 4Y40A 4IC0A 4DY7C 1OO8A 2DUTA 2HIJI 1ATUA 3B9FI 2PEFA 2H4PA 2ZNHA 2ANTI 4ZK3A 2WY0C 5EI0A 1E03I 2XN6A 4AQHA 4G8RA 5HGCA 1DZHL 4AU3B 1AS4A 1MTPA 1KCTA 2ARQA 2PEEA 1JMOA 1LQ8A 3R4LA 3CWMA 2D26A 3CAAA 3DY0A 2VDYA 1OPHA 9APIA 8APIA 1XU8A 4AJTA 1OYHL 5CDZA 3CWLA 1OVAA 2RIWA 4RSQA 2WXWA 2GD4C 4ROAA 4IF8A 4RO9A 1IZ2A 3ZHAA 1QMBA 2XN3A 5CE0A 3KCGI 1DZGL 1OC0A 1QLPA 4BB2A 1NQ9I 4DTEA 4AU4A 5BRRI 1TB6I 2VDXA 3EVJI 1BY7A 1ATHA 2RIVA 1JJOC 1OVAC 1F0CA 1YXAA 3NDDA 2BEHI 4AU3A 4C49A 2B5TI 3DLWA 4R9IA 2V95A 9PAIA 3Q02A 1JVQI 4CAAA 1K9OI 2HIJL 4C41A 2B4XL 1EZXA 1BR8I 4P0FA 2VH4A 5INWA 2H4RA 4EB1L 2HI9A 2XN5A 1DB2A 4KDSA 1XQGA 2WXYC 1HLEA 1LJ5A 1JMJA 3F02A 3LW2A 2ARRA 4G8OA 4ZK0A 2WY1A 2ZV6A 3F5NA 3H5CA 3PZFA 1HP7A 2QUGA 4X30A 2XN7A 1AZXI 1ATTA 4AU2A 2WXZA 5CDXA 1SR5A 1A7CA 1ANTI 1PSIA 2H4QA 3UT3A 4P0OA 3VVJA 1DVNA 1DZHI 3DRMA 1JTIA 3OZQA 3F1SA 2OAYA 4Y3KA 1SNGA 3NE4A 1WZ9A 4ROBA 2R9YA 3CVMA 1UHGA 2B4XI 3EOXA 1LK6I 2WXZC 4GA7A 1D5SA 1JRRA 1R1LI 5C98A 3NDAA 1OYHI 2BEHL 3LE2A 4PYWA 4EB1I 1C5GA 3DRUA 1C8OA 1E04I 1T1FA 4AJUA 4DY0A 4AFXA 2CEOA 2OL2A 3PB1I 1IMVA 1DZGI 1SEKA
chains in the Genus database with same CATH topology
1B3KA 5IO1A 3T1PA 1XQJA 3Q03A 1QMNA 1M93B 3STOA 1DVMA 1E05I 3FGQA 3NDFA 1OVAB 2WXXA 4YIAA 7APIA 2ACHA 4Y40A 4IC0A 4DY7C 1OO8A 2DUTA 2HIJI 1ATUA 3B9FI 2PEFA 2H4PA 2ZNHA 2ANTI 4ZK3A 2WY0C 5EI0A 1E03I 2XN6A 4AQHA 4G8RA 5HGCA 1DZHL 4AU3B 1AS4A 1MTPA 1KCTA 2ARQA 2PEEA 1JMOA 1LQ8A 3R4LA 3CWMA 2D26A 3CAAA 3DY0A 2VDYA 1OPHA 9APIA 8APIA 1XU8A 4AJTA 1OYHL 5CDZA 3CWLA 1OVAA 2RIWA 4RSQA 2WXWA 2GD4C 4ROAA 4IF8A 4RO9A 1IZ2A 3ZHAA 1QMBA 2XN3A 5CE0A 3KCGI 1DZGL 1OC0A 1QLPA 4BB2A 1NQ9I 4DTEA 4AU4A 5BRRI 1TB6I 2VDXA 3EVJI 1BY7A 1ATHA 2RIVA 1JJOC 1OVAC 1F0CA 1YXAA 3NDDA 2BEHI 4AU3A 4C49A 2B5TI 3DLWA 4R9IA 2V95A 9PAIA 3Q02A 1JVQI 4CAAA 1K9OI 2HIJL 4C41A 2B4XL 1EZXA 1BR8I 4P0FA 2VH4A 5INWA 2H4RA 4EB1L 2HI9A 2XN5A 1DB2A 4KDSA 1XQGA 2WXYC 1HLEA 1LJ5A 1JMJA 3F02A 3LW2A 2ARRA 4G8OA 4ZK0A 2WY1A 2ZV6A 3F5NA 3H5CA 3PZFA 1HP7A 2QUGA 4X30A 2XN7A 1AZXI 1ATTA 4AU2A 2WXZA 5CDXA 1SR5A 1A7CA 1ANTI 1PSIA 2H4QA 3UT3A 4P0OA 3VVJA 1DVNA 1DZHI 3DRMA 1JTIA 3OZQA 3F1SA 2OAYA 4Y3KA 1SNGA 3NE4A 1WZ9A 4ROBA 2R9YA 3CVMA 1UHGA 2B4XI 3EOXA 1LK6I 2WXZC 4GA7A 1D5SA 1JRRA 1R1LI 5C98A 3NDAA 1OYHI 2BEHL 3LE2A 4PYWA 4EB1I 1C5GA 3DRUA 1C8OA 1E04I 1T1FA 4AJUA 4DY0A 4AFXA 2CEOA 2OL2A 3PB1I 1IMVA 1DZGI 1SEKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B3K A;  5IO1 A;  3T1P A;  1XQJ A;  3Q03 A;  1QMN A;  1M93 B;  3STO A;  1DVM A;  1E05 I;  3FGQ A;  3NDF A;  1OVA B;  2WXX A;  4YIA A;  7API A;  2ACH A;  4Y40 A;  4IC0 A;  4DY7 C;  1OO8 A;  2DUT A;  2HIJ I;  1ATU A;  3B9F I;  2PEF A;  2H4P A;  2ZNH A;  2ANT I;  4ZK3 A;  2WY0 C;  5EI0 A;  1E03 I;  2XN6 A;  4AQH A;  4G8R A;  5HGC A;  1DZH L;  4AU3 B;  1AS4 A;  1MTP A;  1KCT A;  2ARQ A;  2PEE A;  1JMO A;  1LQ8 A;  3R4L A;  3CWM A;  2D26 A;  3CAA A;  3DY0 A;  2VDY A;  1OPH A;  9API A;  8API A;  1XU8 A;  4AJT A;  1OYH L;  5CDZ A;  3CWL A;  1OVA A;  2RIW A;  4RSQ A;  2WXW A;  2GD4 C;  4ROA A;  4IF8 A;  4RO9 A;  1IZ2 A;  3ZHA A;  1QMB A;  2XN3 A;  5CE0 A;  3KCG I;  1DZG L;  1OC0 A;  1QLP A;  4BB2 A;  1NQ9 I;  4DTE A;  4AU4 A;  5BRR I;  1TB6 I;  2VDX A;  3EVJ I;  1BY7 A;  1ATH A;  2RIV A;  1JJO C;  1OVA C;  1F0C A;  1YXA A;  3NDD A;  2BEH I;  4AU3 A;  4C49 A;  2B5T I;  3DLW A;  4R9I A;  2V95 A;  9PAI A;  3Q02 A;  1JVQ I;  4CAA A;  1K9O I;  2HIJ L;  4C41 A;  2B4X L;  1EZX A;  1BR8 I;  4P0F A;  2VH4 A;  5INW A;  2H4R A;  4EB1 L;  2HI9 A;  2XN5 A;  1DB2 A;  4KDS A;  1XQG A;  2WXY C;  1HLE A;  1LJ5 A;  1JMJ A;  3F02 A;  3LW2 A;  2ARR A;  4G8O A;  4ZK0 A;  2WY1 A;  2ZV6 A;  3F5N A;  3H5C A;  3PZF A;  1HP7 A;  2QUG A;  4X30 A;  2XN7 A;  1AZX I;  1ATT A;  4AU2 A;  2WXZ A;  5CDX A;  1SR5 A;  1A7C A;  1ANT I;  1PSI A;  2H4Q A;  3UT3 A;  4P0O A;  3VVJ A;  1DVN A;  1DZH I;  3DRM A;  1JTI A;  3OZQ A;  3F1S A;  2OAY A;  4Y3K A;  1SNG A;  3NE4 A;  1WZ9 A;  4ROB A;  2R9Y A;  3CVM A;  1UHG A;  2B4X I;  3EOX A;  1LK6 I;  2WXZ C;  4GA7 A;  1D5S A;  1JRR A;  1R1L I;  5C98 A;  3NDA A;  1OYH I;  2BEH L;  3LE2 A;  4PYW A;  4EB1 I;  1C5G A;  3DRU A;  1C8O A;  1E04 I;  1T1F A;  4AJU A;  4DY0 A;  4AFX A;  2CEO A;  2OL2 A;  3PB1 I;  1IMV A;  1DZG I;  1SEK A; 
#chains in the Genus database with same CATH topology
 1B3K A;  5IO1 A;  3T1P A;  1XQJ A;  3Q03 A;  1QMN A;  1M93 B;  3STO A;  1DVM A;  1E05 I;  3FGQ A;  3NDF A;  1OVA B;  2WXX A;  4YIA A;  7API A;  2ACH A;  4Y40 A;  4IC0 A;  4DY7 C;  1OO8 A;  2DUT A;  2HIJ I;  1ATU A;  3B9F I;  2PEF A;  2H4P A;  2ZNH A;  2ANT I;  4ZK3 A;  2WY0 C;  5EI0 A;  1E03 I;  2XN6 A;  4AQH A;  4G8R A;  5HGC A;  1DZH L;  4AU3 B;  1AS4 A;  1MTP A;  1KCT A;  2ARQ A;  2PEE A;  1JMO A;  1LQ8 A;  3R4L A;  3CWM A;  2D26 A;  3CAA A;  3DY0 A;  2VDY A;  1OPH A;  9API A;  8API A;  1XU8 A;  4AJT A;  1OYH L;  5CDZ A;  3CWL A;  1OVA A;  2RIW A;  4RSQ A;  2WXW A;  2GD4 C;  4ROA A;  4IF8 A;  4RO9 A;  1IZ2 A;  3ZHA A;  1QMB A;  2XN3 A;  5CE0 A;  3KCG I;  1DZG L;  1OC0 A;  1QLP A;  4BB2 A;  1NQ9 I;  4DTE A;  4AU4 A;  5BRR I;  1TB6 I;  2VDX A;  3EVJ I;  1BY7 A;  1ATH A;  2RIV A;  1JJO C;  1OVA C;  1F0C A;  1YXA A;  3NDD A;  2BEH I;  4AU3 A;  4C49 A;  2B5T I;  3DLW A;  4R9I A;  2V95 A;  9PAI A;  3Q02 A;  1JVQ I;  4CAA A;  1K9O I;  2HIJ L;  4C41 A;  2B4X L;  1EZX A;  1BR8 I;  4P0F A;  2VH4 A;  5INW A;  2H4R A;  4EB1 L;  2HI9 A;  2XN5 A;  1DB2 A;  4KDS A;  1XQG A;  2WXY C;  1HLE A;  1LJ5 A;  1JMJ A;  3F02 A;  3LW2 A;  2ARR A;  4G8O A;  4ZK0 A;  2WY1 A;  2ZV6 A;  3F5N A;  3H5C A;  3PZF A;  1HP7 A;  2QUG A;  4X30 A;  2XN7 A;  1AZX I;  1ATT A;  4AU2 A;  2WXZ A;  5CDX A;  1SR5 A;  1A7C A;  1ANT I;  1PSI A;  2H4Q A;  3UT3 A;  4P0O A;  3VVJ A;  1DVN A;  1DZH I;  3DRM A;  1JTI A;  3OZQ A;  3F1S A;  2OAY A;  4Y3K A;  1SNG A;  3NE4 A;  1WZ9 A;  4ROB A;  2R9Y A;  3CVM A;  1UHG A;  2B4X I;  3EOX A;  1LK6 I;  2WXZ C;  4GA7 A;  1D5S A;  1JRR A;  1R1L I;  5C98 A;  3NDA A;  1OYH I;  2BEH L;  3LE2 A;  4PYW A;  4EB1 I;  1C5G A;  3DRU A;  1C8O A;  1E04 I;  1T1F A;  4AJU A;  4DY0 A;  4AFX A;  2CEO A;  2OL2 A;  3PB1 I;  1IMV A;  1DZG I;  1SEK A; 
#chains in the Genus database with same CATH homology
 1B3K A;  5IO1 A;  3T1P A;  1XQJ A;  3Q03 A;  1QMN A;  1M93 B;  3STO A;  1DVM A;  1E05 I;  3FGQ A;  3NDF A;  1OVA B;  2WXX A;  4YIA A;  7API A;  2ACH A;  4Y40 A;  4IC0 A;  4DY7 C;  1OO8 A;  2DUT A;  2HIJ I;  1ATU A;  3B9F I;  2PEF A;  2H4P A;  2ZNH A;  2ANT I;  4ZK3 A;  2WY0 C;  5EI0 A;  1E03 I;  2XN6 A;  4AQH A;  4G8R A;  5HGC A;  1DZH L;  4AU3 B;  1AS4 A;  1MTP A;  1KCT A;  2ARQ A;  2PEE A;  1JMO A;  1LQ8 A;  3R4L A;  3CWM A;  2D26 A;  3CAA A;  3DY0 A;  2VDY A;  1OPH A;  9API A;  8API A;  1XU8 A;  4AJT A;  1OYH L;  5CDZ A;  3CWL A;  1OVA A;  2RIW A;  4RSQ A;  2WXW A;  2GD4 C;  4ROA A;  4IF8 A;  4RO9 A;  1IZ2 A;  3ZHA A;  1QMB A;  2XN3 A;  5CE0 A;  3KCG I;  1DZG L;  1OC0 A;  1QLP A;  4BB2 A;  1NQ9 I;  4DTE A;  4AU4 A;  5BRR I;  1TB6 I;  2VDX A;  3EVJ I;  1BY7 A;  1ATH A;  2RIV A;  1JJO C;  1OVA C;  1F0C A;  1YXA A;  3NDD A;  2BEH I;  4AU3 A;  4C49 A;  2B5T I;  3DLW A;  4R9I A;  2V95 A;  9PAI A;  3Q02 A;  1JVQ I;  4CAA A;  1K9O I;  2HIJ L;  4C41 A;  2B4X L;  1EZX A;  1BR8 I;  4P0F A;  2VH4 A;  5INW A;  2H4R A;  4EB1 L;  2HI9 A;  2XN5 A;  1DB2 A;  4KDS A;  1XQG A;  2WXY C;  1HLE A;  1LJ5 A;  1JMJ A;  3F02 A;  3LW2 A;  2ARR A;  4G8O A;  4ZK0 A;  2WY1 A;  2ZV6 A;  3F5N A;  3H5C A;  3PZF A;  1HP7 A;  2QUG A;  4X30 A;  2XN7 A;  1AZX I;  1ATT A;  4AU2 A;  2WXZ A;  5CDX A;  1SR5 A;  1A7C A;  1ANT I;  1PSI A;  2H4Q A;  3UT3 A;  4P0O A;  3VVJ A;  1DVN A;  1DZH I;  3DRM A;  1JTI A;  3OZQ A;  3F1S A;  2OAY A;  4Y3K A;  1SNG A;  3NE4 A;  1WZ9 A;  4ROB A;  2R9Y A;  3CVM A;  1UHG A;  2B4X I;  3EOX A;  1LK6 I;  2WXZ C;  4GA7 A;  1D5S A;  1JRR A;  1R1L I;  5C98 A;  3NDA A;  1OYH I;  2BEH L;  3LE2 A;  4PYW A;  4EB1 I;  1C5G A;  3DRU A;  1C8O A;  1E04 I;  1T1F A;  4AJU A;  4DY0 A;  4AFX A;  2CEO A;  2OL2 A;  3PB1 I;  1IMV A;  1DZG I;  1SEK A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...