2OL2A

High resolution structure of native pci in space group p21
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
360
structure length
360
Chain Sequence
DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of native protein C inhibitor provides insight into its multiple functions.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Homo sapiens
molecule keywords Plasma serine protease inhibitor
total genus 99
structure length 360
sequence length 360
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2ol2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2ol2A01
5BRRI 2XN5A 1BR8I 1SR5A 1E05I 2XN3A 4G8OA 2WXWA 1QMBA 3B9FI 1ATTA 2WY0C 1OYHL 3DRMA 4IF8A 1ATHA 3DRUA 4RSQA 3NDFA 4ROAA 1F0CA 1OO8A 1K9OI 2BEHI 2R9YA 2ZNHA 1A7CA 4RO9A 2PEEA 2DUTA 4EB1I 5CDZA 1JTIA 4GA7A 5EI0A 4Y3KA 1NQ9I 3CAAA 3H5CA 4AU3B 2RIWA 2HIJI 2ARRA 3CWMA 2OL2A 2PEFA 3F02A 4AJUA 4CAAA 3F5NA 1ANTI 1DVNA 3R4LA 4BB2A 2BEHL 1OC0A 1IZ2A 3CVMA 3FGQA 1AZXI 2XN7A 3PZFA 1DZGI 3PB1I 2CEOA 1E04I 4EB1L 2RIVA 3T1PA 2ARQA 1JMOA 3EVJI 2ACHA 4Y40A 2B4XL 1AS4A 3CWLA 1OVAB 4AFXA 2HIJL 5IO1A 4AU4A 3Q03A 3UT3A 3STOA 2XN6A 2B4XI 2ZV6A 9APIA 1HLEA 4DY7C 2WXXA 1C8OA 2B5TI 2WXZC 2V95A 2D26A 2WXZA 2H4PA 1DZGL 1KCTA 4P0OA 4R9IA 4YIAA 1IMVA 1SEKA 3DY0A 4C49A 3DLWA 2VDXA 1JVQI 3KCGI 3NE4A 2GD4C 2QUGA 1DB2A 1DVMA 3LE2A 1PSIA 3ZHAA 4KDSA 2OAYA 4AJTA 4C41A 4ZK0A 1D5SA 1EZXA 2H4RA 4AU3A 5CE0A 1WZ9A 1B3KA 1DZHI 5C98A 2H4QA 1JMJA 1JJOC 1E03I 3NDAA 4PYWA 2HI9A 4AQHA 8APIA 2ANTI 2VH4A 1QLPA 1UHGA 3OZQA 4P0FA 1JRRA 4ZK3A 4DY0A 1HP7A 1BY7A 5HGCA 1T1FA 1LQ8A 1XQJA 4ROBA 1C5GA 9PAIA 1QMNA 1OVAC 1LK6I 3NDDA 4G8RA 1OPHA 1MTPA 1OVAA 1M93B 1OYHI 1DZHL 1SNGA 4IC0A 3VVJA 5CDXA 4X30A 4AU2A 1TB6I 2VDYA 1R1LI 5INWA 3EOXA 3LW2A 4DTEA 1YXAA 1XQGA 3Q02A 1ATUA 2WY1A 7APIA 3F1SA 1XU8A 2WXYC 1LJ5A
chains in the Genus database with same CATH superfamily
5BRRI 2XN5A 1BR8I 1SR5A 1E05I 2XN3A 4G8OA 2WXWA 1QMBA 3B9FI 1ATTA 2WY0C 1OYHL 3DRMA 4IF8A 1ATHA 3DRUA 4RSQA 3NDFA 4ROAA 1F0CA 1OO8A 1K9OI 2BEHI 2R9YA 2ZNHA 1A7CA 4RO9A 2PEEA 2DUTA 4EB1I 5CDZA 1JTIA 4GA7A 5EI0A 4Y3KA 1NQ9I 3CAAA 3H5CA 4AU3B 2RIWA 2HIJI 2ARRA 3CWMA 2OL2A 2PEFA 3F02A 4AJUA 4CAAA 3F5NA 1ANTI 1DVNA 3R4LA 4BB2A 2BEHL 1OC0A 1IZ2A 3CVMA 3FGQA 1AZXI 2XN7A 3PZFA 1DZGI 3PB1I 2CEOA 1E04I 4EB1L 2RIVA 3T1PA 2ARQA 1JMOA 3EVJI 2ACHA 4Y40A 2B4XL 1AS4A 3CWLA 1OVAB 4AFXA 2HIJL 5IO1A 4AU4A 3Q03A 3UT3A 3STOA 2XN6A 2B4XI 2ZV6A 9APIA 1HLEA 4DY7C 2WXXA 1C8OA 2B5TI 2WXZC 2V95A 2D26A 2WXZA 2H4PA 1DZGL 1KCTA 4P0OA 4R9IA 4YIAA 1IMVA 1SEKA 3DY0A 4C49A 3DLWA 2VDXA 1JVQI 3KCGI 3NE4A 2GD4C 2QUGA 1DB2A 1DVMA 3LE2A 1PSIA 3ZHAA 4KDSA 2OAYA 4AJTA 4C41A 4ZK0A 1D5SA 1EZXA 2H4RA 4AU3A 5CE0A 1WZ9A 1B3KA 1DZHI 5C98A 2H4QA 1JMJA 1JJOC 1E03I 3NDAA 4PYWA 2HI9A 4AQHA 8APIA 2ANTI 2VH4A 1QLPA 1UHGA 3OZQA 4P0FA 1JRRA 4ZK3A 4DY0A 1HP7A 1BY7A 5HGCA 1T1FA 1LQ8A 1XQJA 4ROBA 1C5GA 9PAIA 1QMNA 1OVAC 1LK6I 3NDDA 4G8RA 1OPHA 1MTPA 1OVAA 1M93B 1OYHI 1DZHL 1SNGA 4IC0A 3VVJA 5CDXA 4X30A 4AU2A 1TB6I 2VDYA 1R1LI 5INWA 3EOXA 3LW2A 4DTEA 1YXAA 1XQGA 3Q02A 1ATUA 2WY1A 7APIA 3F1SA 1XU8A 2WXYC 1LJ5A
chains in the Genus database with same CATH topology
5BRRI 2XN5A 1BR8I 1SR5A 1E05I 2XN3A 4G8OA 2WXWA 1QMBA 3B9FI 1ATTA 2WY0C 1OYHL 3DRMA 4IF8A 1ATHA 3DRUA 4RSQA 3NDFA 4ROAA 1F0CA 1OO8A 1K9OI 2BEHI 2R9YA 2ZNHA 1A7CA 4RO9A 2PEEA 2DUTA 4EB1I 5CDZA 1JTIA 4GA7A 5EI0A 4Y3KA 1NQ9I 3CAAA 3H5CA 4AU3B 2RIWA 2HIJI 2ARRA 3CWMA 2OL2A 2PEFA 3F02A 4AJUA 4CAAA 3F5NA 1ANTI 1DVNA 3R4LA 4BB2A 2BEHL 1OC0A 1IZ2A 3CVMA 3FGQA 1AZXI 2XN7A 3PZFA 1DZGI 3PB1I 2CEOA 1E04I 4EB1L 2RIVA 3T1PA 2ARQA 1JMOA 3EVJI 2ACHA 4Y40A 2B4XL 1AS4A 3CWLA 1OVAB 4AFXA 2HIJL 5IO1A 4AU4A 3Q03A 3UT3A 3STOA 2XN6A 2B4XI 2ZV6A 9APIA 1HLEA 4DY7C 2WXXA 1C8OA 2B5TI 2WXZC 2V95A 2D26A 2WXZA 2H4PA 1DZGL 1KCTA 4P0OA 4R9IA 4YIAA 1IMVA 1SEKA 3DY0A 4C49A 3DLWA 2VDXA 1JVQI 3KCGI 3NE4A 2GD4C 2QUGA 1DB2A 1DVMA 3LE2A 1PSIA 3ZHAA 4KDSA 2OAYA 4AJTA 4C41A 4ZK0A 1D5SA 1EZXA 2H4RA 4AU3A 5CE0A 1WZ9A 1B3KA 1DZHI 5C98A 2H4QA 1JMJA 1JJOC 1E03I 3NDAA 4PYWA 2HI9A 4AQHA 8APIA 2ANTI 2VH4A 1QLPA 1UHGA 3OZQA 4P0FA 1JRRA 4ZK3A 4DY0A 1HP7A 1BY7A 5HGCA 1T1FA 1LQ8A 1XQJA 4ROBA 1C5GA 9PAIA 1QMNA 1OVAC 1LK6I 3NDDA 4G8RA 1OPHA 1MTPA 1OVAA 1M93B 1OYHI 1DZHL 1SNGA 4IC0A 3VVJA 5CDXA 4X30A 4AU2A 1TB6I 2VDYA 1R1LI 5INWA 3EOXA 3LW2A 4DTEA 1YXAA 1XQGA 3Q02A 1ATUA 2WY1A 7APIA 3F1SA 1XU8A 2WXYC 1LJ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BRR I;  2XN5 A;  1BR8 I;  1SR5 A;  1E05 I;  2XN3 A;  4G8O A;  2WXW A;  1QMB A;  3B9F I;  1ATT A;  2WY0 C;  1OYH L;  3DRM A;  4IF8 A;  1ATH A;  3DRU A;  4RSQ A;  3NDF A;  4ROA A;  1F0C A;  1OO8 A;  1K9O I;  2BEH I;  2R9Y A;  2ZNH A;  1A7C A;  4RO9 A;  2PEE A;  2DUT A;  4EB1 I;  5CDZ A;  1JTI A;  4GA7 A;  5EI0 A;  4Y3K A;  1NQ9 I;  3CAA A;  3H5C A;  4AU3 B;  2RIW A;  2HIJ I;  2ARR A;  3CWM A;  2OL2 A;  2PEF A;  3F02 A;  4AJU A;  4CAA A;  3F5N A;  1ANT I;  1DVN A;  3R4L A;  4BB2 A;  2BEH L;  1OC0 A;  1IZ2 A;  3CVM A;  3FGQ A;  1AZX I;  2XN7 A;  3PZF A;  1DZG I;  3PB1 I;  2CEO A;  1E04 I;  4EB1 L;  2RIV A;  3T1P A;  2ARQ A;  1JMO A;  3EVJ I;  2ACH A;  4Y40 A;  2B4X L;  1AS4 A;  3CWL A;  1OVA B;  4AFX A;  2HIJ L;  5IO1 A;  4AU4 A;  3Q03 A;  3UT3 A;  3STO A;  2XN6 A;  2B4X I;  2ZV6 A;  9API A;  1HLE A;  4DY7 C;  2WXX A;  1C8O A;  2B5T I;  2WXZ C;  2V95 A;  2D26 A;  2WXZ A;  2H4P A;  1DZG L;  1KCT A;  4P0O A;  4R9I A;  4YIA A;  1IMV A;  1SEK A;  3DY0 A;  4C49 A;  3DLW A;  2VDX A;  1JVQ I;  3KCG I;  3NE4 A;  2GD4 C;  2QUG A;  1DB2 A;  1DVM A;  3LE2 A;  1PSI A;  3ZHA A;  4KDS A;  2OAY A;  4AJT A;  4C41 A;  4ZK0 A;  1D5S A;  1EZX A;  2H4R A;  4AU3 A;  5CE0 A;  1WZ9 A;  1B3K A;  1DZH I;  5C98 A;  2H4Q A;  1JMJ A;  1JJO C;  1E03 I;  3NDA A;  4PYW A;  2HI9 A;  4AQH A;  8API A;  2ANT I;  2VH4 A;  1QLP A;  1UHG A;  3OZQ A;  4P0F A;  1JRR A;  4ZK3 A;  4DY0 A;  1HP7 A;  1BY7 A;  5HGC A;  1T1F A;  1LQ8 A;  1XQJ A;  4ROB A;  1C5G A;  9PAI A;  1QMN A;  1OVA C;  1LK6 I;  3NDD A;  4G8R A;  1OPH A;  1MTP A;  1OVA A;  1M93 B;  1OYH I;  1DZH L;  1SNG A;  4IC0 A;  3VVJ A;  5CDX A;  4X30 A;  4AU2 A;  1TB6 I;  2VDY A;  1R1L I;  5INW A;  3EOX A;  3LW2 A;  4DTE A;  1YXA A;  1XQG A;  3Q02 A;  1ATU A;  2WY1 A;  7API A;  3F1S A;  1XU8 A;  2WXY C;  1LJ5 A; 
#chains in the Genus database with same CATH topology
 5BRR I;  2XN5 A;  1BR8 I;  1SR5 A;  1E05 I;  2XN3 A;  4G8O A;  2WXW A;  1QMB A;  3B9F I;  1ATT A;  2WY0 C;  1OYH L;  3DRM A;  4IF8 A;  1ATH A;  3DRU A;  4RSQ A;  3NDF A;  4ROA A;  1F0C A;  1OO8 A;  1K9O I;  2BEH I;  2R9Y A;  2ZNH A;  1A7C A;  4RO9 A;  2PEE A;  2DUT A;  4EB1 I;  5CDZ A;  1JTI A;  4GA7 A;  5EI0 A;  4Y3K A;  1NQ9 I;  3CAA A;  3H5C A;  4AU3 B;  2RIW A;  2HIJ I;  2ARR A;  3CWM A;  2OL2 A;  2PEF A;  3F02 A;  4AJU A;  4CAA A;  3F5N A;  1ANT I;  1DVN A;  3R4L A;  4BB2 A;  2BEH L;  1OC0 A;  1IZ2 A;  3CVM A;  3FGQ A;  1AZX I;  2XN7 A;  3PZF A;  1DZG I;  3PB1 I;  2CEO A;  1E04 I;  4EB1 L;  2RIV A;  3T1P A;  2ARQ A;  1JMO A;  3EVJ I;  2ACH A;  4Y40 A;  2B4X L;  1AS4 A;  3CWL A;  1OVA B;  4AFX A;  2HIJ L;  5IO1 A;  4AU4 A;  3Q03 A;  3UT3 A;  3STO A;  2XN6 A;  2B4X I;  2ZV6 A;  9API A;  1HLE A;  4DY7 C;  2WXX A;  1C8O A;  2B5T I;  2WXZ C;  2V95 A;  2D26 A;  2WXZ A;  2H4P A;  1DZG L;  1KCT A;  4P0O A;  4R9I A;  4YIA A;  1IMV A;  1SEK A;  3DY0 A;  4C49 A;  3DLW A;  2VDX A;  1JVQ I;  3KCG I;  3NE4 A;  2GD4 C;  2QUG A;  1DB2 A;  1DVM A;  3LE2 A;  1PSI A;  3ZHA A;  4KDS A;  2OAY A;  4AJT A;  4C41 A;  4ZK0 A;  1D5S A;  1EZX A;  2H4R A;  4AU3 A;  5CE0 A;  1WZ9 A;  1B3K A;  1DZH I;  5C98 A;  2H4Q A;  1JMJ A;  1JJO C;  1E03 I;  3NDA A;  4PYW A;  2HI9 A;  4AQH A;  8API A;  2ANT I;  2VH4 A;  1QLP A;  1UHG A;  3OZQ A;  4P0F A;  1JRR A;  4ZK3 A;  4DY0 A;  1HP7 A;  1BY7 A;  5HGC A;  1T1F A;  1LQ8 A;  1XQJ A;  4ROB A;  1C5G A;  9PAI A;  1QMN A;  1OVA C;  1LK6 I;  3NDD A;  4G8R A;  1OPH A;  1MTP A;  1OVA A;  1M93 B;  1OYH I;  1DZH L;  1SNG A;  4IC0 A;  3VVJ A;  5CDX A;  4X30 A;  4AU2 A;  1TB6 I;  2VDY A;  1R1L I;  5INW A;  3EOX A;  3LW2 A;  4DTE A;  1YXA A;  1XQG A;  3Q02 A;  1ATU A;  2WY1 A;  7API A;  3F1S A;  1XU8 A;  2WXY C;  1LJ5 A; 
#chains in the Genus database with same CATH homology
 5BRR I;  2XN5 A;  1BR8 I;  1SR5 A;  1E05 I;  2XN3 A;  4G8O A;  2WXW A;  1QMB A;  3B9F I;  1ATT A;  2WY0 C;  1OYH L;  3DRM A;  4IF8 A;  1ATH A;  3DRU A;  4RSQ A;  3NDF A;  4ROA A;  1F0C A;  1OO8 A;  1K9O I;  2BEH I;  2R9Y A;  2ZNH A;  1A7C A;  4RO9 A;  2PEE A;  2DUT A;  4EB1 I;  5CDZ A;  1JTI A;  4GA7 A;  5EI0 A;  4Y3K A;  1NQ9 I;  3CAA A;  3H5C A;  4AU3 B;  2RIW A;  2HIJ I;  2ARR A;  3CWM A;  2OL2 A;  2PEF A;  3F02 A;  4AJU A;  4CAA A;  3F5N A;  1ANT I;  1DVN A;  3R4L A;  4BB2 A;  2BEH L;  1OC0 A;  1IZ2 A;  3CVM A;  3FGQ A;  1AZX I;  2XN7 A;  3PZF A;  1DZG I;  3PB1 I;  2CEO A;  1E04 I;  4EB1 L;  2RIV A;  3T1P A;  2ARQ A;  1JMO A;  3EVJ I;  2ACH A;  4Y40 A;  2B4X L;  1AS4 A;  3CWL A;  1OVA B;  4AFX A;  2HIJ L;  5IO1 A;  4AU4 A;  3Q03 A;  3UT3 A;  3STO A;  2XN6 A;  2B4X I;  2ZV6 A;  9API A;  1HLE A;  4DY7 C;  2WXX A;  1C8O A;  2B5T I;  2WXZ C;  2V95 A;  2D26 A;  2WXZ A;  2H4P A;  1DZG L;  1KCT A;  4P0O A;  4R9I A;  4YIA A;  1IMV A;  1SEK A;  3DY0 A;  4C49 A;  3DLW A;  2VDX A;  1JVQ I;  3KCG I;  3NE4 A;  2GD4 C;  2QUG A;  1DB2 A;  1DVM A;  3LE2 A;  1PSI A;  3ZHA A;  4KDS A;  2OAY A;  4AJT A;  4C41 A;  4ZK0 A;  1D5S A;  1EZX A;  2H4R A;  4AU3 A;  5CE0 A;  1WZ9 A;  1B3K A;  1DZH I;  5C98 A;  2H4Q A;  1JMJ A;  1JJO C;  1E03 I;  3NDA A;  4PYW A;  2HI9 A;  4AQH A;  8API A;  2ANT I;  2VH4 A;  1QLP A;  1UHG A;  3OZQ A;  4P0F A;  1JRR A;  4ZK3 A;  4DY0 A;  1HP7 A;  1BY7 A;  5HGC A;  1T1F A;  1LQ8 A;  1XQJ A;  4ROB A;  1C5G A;  9PAI A;  1QMN A;  1OVA C;  1LK6 I;  3NDD A;  4G8R A;  1OPH A;  1MTP A;  1OVA A;  1M93 B;  1OYH I;  1DZH L;  1SNG A;  4IC0 A;  3VVJ A;  5CDX A;  4X30 A;  4AU2 A;  1TB6 I;  2VDY A;  1R1L I;  5INW A;  3EOX A;  3LW2 A;  4DTE A;  1YXA A;  1XQG A;  3Q02 A;  1ATU A;  2WY1 A;  7API A;  3F1S A;  1XU8 A;  2WXY C;  1LJ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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