2PEEA

Crystal structure of a thermophilic serpin, tengpin, in the native state
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
387
structure length
387
Chain Sequence
VQAANLMDRIKANPVSEKNIDEKFIYNTADFSIELFKNSIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALGKDISIEDLNKYLYTYMKKLPNEEKSKLTIANSIWFKENDFMPSKDFLQIIADYYKADIFKAAFDSSTVSDINNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEWETVYEKASVHEDIFTDVYGNRQKVEFMNSEENLYIEEENAIGFVKPYAKNHYSFVAILPDENISVNEYIKTLTGQKFIDLIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTDAFLPDKADFSKLGKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFKTVKLNRPFIFAIIDNSTNLPIFIGTVLSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The N terminus of the serpin, tengpin, functions to trap the metastable native state.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Thermoanaerobacter tengcongensis
molecule keywords Serine protease inhibitor
total genus 121
structure length 387
sequence length 387
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2peeA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2peeA01
2ARQA 4YIAA 1LJ5A 4X30A 4C49A 1DZHI 3CAAA 5IO1A 3KCGI 5BRRI 2H4RA 3R4LA 2WXXA 3NE4A 1QMNA 5HGCA 1HP7A 5CDXA 1E03I 3EOXA 3LE2A 3PZFA 1DZGI 4GA7A 1R1LI 3Q02A 5EI0A 3F1SA 1QMBA 4IC0A 2HIJI 9PAIA 4RSQA 4Y40A 2DUTA 5INWA 4AU2A 4AQHA 4BB2A 4ZK0A 1UHGA 4DTEA 1SNGA 3T1PA 2VH4A 2B4XL 1OYHI 3DLWA 4AJUA 2WXZA 3B9FI 2VDXA 1JMJA 1TB6I 4P0OA 4RO9A 1XQGA 3H5CA 1B3KA 1JVQI 2QUGA 4ROBA 1DVNA 4DY7C 2XN7A 3ZHAA 1JRRA 4P0FA 1BY7A 2WY1A 2WY0C 3DRUA 1ATHA 1ANTI 2PEEA 3Q03A 1C8OA 1AZXI 4C41A 1F0CA 1SEKA 2BEHI 1JTIA 1LK6I 1K9OI 2D26A 2ARRA 2OAYA 2HI9A 5CDZA 2VDYA 3STOA 1OVAA 2XN3A 3F02A 1OC0A 1AS4A 3NDFA 4AU4A 5C98A 1IZ2A 4CAAA 1XQJA 1IMVA 3DY0A 2WXZC 5CE0A 4EB1L 1DZHL 7APIA 4ROAA 1E05I 1XU8A 2WXWA 2XN5A 4G8RA 2R9YA 2RIVA 2B5TI 2XN6A 1DZGL 1E04I 4IF8A 4ZK3A 4AU3A 1OO8A 2WXYC 3NDDA 2ZNHA 4G8OA 1PSIA 4Y3KA 2OL2A 1HLEA 3NDAA 2B4XI 2RIWA 1YXAA 4AJTA 9APIA 8APIA 1DVMA 1OYHL 1LQ8A 2GD4C 2V95A 3PB1I 4EB1I 1OVAB 4R9IA 1NQ9I 1T1FA 3DRMA 3VVJA 1OVAC 1DB2A 2ANTI 4AFXA 1JJOC 2ZV6A 1C5GA 2PEFA 2CEOA 3CVMA 3EVJI 3CWMA 1EZXA 2H4PA 3UT3A 4DY0A 1SR5A 1WZ9A 3F5NA 2H4QA 2HIJL 1KCTA 2ACHA 3OZQA 4AU3B 1ATTA 4PYWA 3CWLA 1OPHA 3LW2A 2BEHL 1JMOA 1ATUA 1M93B 4KDSA 1QLPA 1A7CA 3FGQA 1BR8I 1D5SA 1MTPA
chains in the Genus database with same CATH superfamily
2ARQA 4YIAA 1LJ5A 4X30A 4C49A 1DZHI 3CAAA 5IO1A 3KCGI 5BRRI 2H4RA 3R4LA 2WXXA 3NE4A 1QMNA 5HGCA 1HP7A 5CDXA 1E03I 3EOXA 3LE2A 3PZFA 1DZGI 4GA7A 1R1LI 3Q02A 5EI0A 3F1SA 1QMBA 4IC0A 2HIJI 9PAIA 4RSQA 4Y40A 2DUTA 5INWA 4AU2A 4AQHA 4BB2A 4ZK0A 1UHGA 4DTEA 1SNGA 3T1PA 2VH4A 2B4XL 1OYHI 3DLWA 4AJUA 2WXZA 3B9FI 2VDXA 1JMJA 1TB6I 4P0OA 4RO9A 1XQGA 3H5CA 1B3KA 1JVQI 2QUGA 4ROBA 1DVNA 4DY7C 2XN7A 3ZHAA 1JRRA 4P0FA 1BY7A 2WY1A 2WY0C 3DRUA 1ATHA 1ANTI 2PEEA 3Q03A 1C8OA 1AZXI 4C41A 1F0CA 1SEKA 2BEHI 1JTIA 1LK6I 1K9OI 2D26A 2ARRA 2OAYA 2HI9A 5CDZA 2VDYA 3STOA 1OVAA 2XN3A 3F02A 1OC0A 1AS4A 3NDFA 4AU4A 5C98A 1IZ2A 4CAAA 1XQJA 1IMVA 3DY0A 2WXZC 5CE0A 4EB1L 1DZHL 7APIA 4ROAA 1E05I 1XU8A 2WXWA 2XN5A 4G8RA 2R9YA 2RIVA 2B5TI 2XN6A 1DZGL 1E04I 4IF8A 4ZK3A 4AU3A 1OO8A 2WXYC 3NDDA 2ZNHA 4G8OA 1PSIA 4Y3KA 2OL2A 1HLEA 3NDAA 2B4XI 2RIWA 1YXAA 4AJTA 9APIA 8APIA 1DVMA 1OYHL 1LQ8A 2GD4C 2V95A 3PB1I 4EB1I 1OVAB 4R9IA 1NQ9I 1T1FA 3DRMA 3VVJA 1OVAC 1DB2A 2ANTI 4AFXA 1JJOC 2ZV6A 1C5GA 2PEFA 2CEOA 3CVMA 3EVJI 3CWMA 1EZXA 2H4PA 3UT3A 4DY0A 1SR5A 1WZ9A 3F5NA 2H4QA 2HIJL 1KCTA 2ACHA 3OZQA 4AU3B 1ATTA 4PYWA 3CWLA 1OPHA 3LW2A 2BEHL 1JMOA 1ATUA 1M93B 4KDSA 1QLPA 1A7CA 3FGQA 1BR8I 1D5SA 1MTPA
chains in the Genus database with same CATH topology
2ARQA 4YIAA 1LJ5A 4X30A 4C49A 1DZHI 3CAAA 5IO1A 3KCGI 5BRRI 2H4RA 3R4LA 2WXXA 3NE4A 1QMNA 5HGCA 1HP7A 5CDXA 1E03I 3EOXA 3LE2A 3PZFA 1DZGI 4GA7A 1R1LI 3Q02A 5EI0A 3F1SA 1QMBA 4IC0A 2HIJI 9PAIA 4RSQA 4Y40A 2DUTA 5INWA 4AU2A 4AQHA 4BB2A 4ZK0A 1UHGA 4DTEA 1SNGA 3T1PA 2VH4A 2B4XL 1OYHI 3DLWA 4AJUA 2WXZA 3B9FI 2VDXA 1JMJA 1TB6I 4P0OA 4RO9A 1XQGA 3H5CA 1B3KA 1JVQI 2QUGA 4ROBA 1DVNA 4DY7C 2XN7A 3ZHAA 1JRRA 4P0FA 1BY7A 2WY1A 2WY0C 3DRUA 1ATHA 1ANTI 2PEEA 3Q03A 1C8OA 1AZXI 4C41A 1F0CA 1SEKA 2BEHI 1JTIA 1LK6I 1K9OI 2D26A 2ARRA 2OAYA 2HI9A 5CDZA 2VDYA 3STOA 1OVAA 2XN3A 3F02A 1OC0A 1AS4A 3NDFA 4AU4A 5C98A 1IZ2A 4CAAA 1XQJA 1IMVA 3DY0A 2WXZC 5CE0A 4EB1L 1DZHL 7APIA 4ROAA 1E05I 1XU8A 2WXWA 2XN5A 4G8RA 2R9YA 2RIVA 2B5TI 2XN6A 1DZGL 1E04I 4IF8A 4ZK3A 4AU3A 1OO8A 2WXYC 3NDDA 2ZNHA 4G8OA 1PSIA 4Y3KA 2OL2A 1HLEA 3NDAA 2B4XI 2RIWA 1YXAA 4AJTA 9APIA 8APIA 1DVMA 1OYHL 1LQ8A 2GD4C 2V95A 3PB1I 4EB1I 1OVAB 4R9IA 1NQ9I 1T1FA 3DRMA 3VVJA 1OVAC 1DB2A 2ANTI 4AFXA 1JJOC 2ZV6A 1C5GA 2PEFA 2CEOA 3CVMA 3EVJI 3CWMA 1EZXA 2H4PA 3UT3A 4DY0A 1SR5A 1WZ9A 3F5NA 2H4QA 2HIJL 1KCTA 2ACHA 3OZQA 4AU3B 1ATTA 4PYWA 3CWLA 1OPHA 3LW2A 2BEHL 1JMOA 1ATUA 1M93B 4KDSA 1QLPA 1A7CA 3FGQA 1BR8I 1D5SA 1MTPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ARQ A;  4YIA A;  1LJ5 A;  4X30 A;  4C49 A;  1DZH I;  3CAA A;  5IO1 A;  3KCG I;  5BRR I;  2H4R A;  3R4L A;  2WXX A;  3NE4 A;  1QMN A;  5HGC A;  1HP7 A;  5CDX A;  1E03 I;  3EOX A;  3LE2 A;  3PZF A;  1DZG I;  4GA7 A;  1R1L I;  3Q02 A;  5EI0 A;  3F1S A;  1QMB A;  4IC0 A;  2HIJ I;  9PAI A;  4RSQ A;  4Y40 A;  2DUT A;  5INW A;  4AU2 A;  4AQH A;  4BB2 A;  4ZK0 A;  1UHG A;  4DTE A;  1SNG A;  3T1P A;  2VH4 A;  2B4X L;  1OYH I;  3DLW A;  4AJU A;  2WXZ A;  3B9F I;  2VDX A;  1JMJ A;  1TB6 I;  4P0O A;  4RO9 A;  1XQG A;  3H5C A;  1B3K A;  1JVQ I;  2QUG A;  4ROB A;  1DVN A;  4DY7 C;  2XN7 A;  3ZHA A;  1JRR A;  4P0F A;  1BY7 A;  2WY1 A;  2WY0 C;  3DRU A;  1ATH A;  1ANT I;  2PEE A;  3Q03 A;  1C8O A;  1AZX I;  4C41 A;  1F0C A;  1SEK A;  2BEH I;  1JTI A;  1LK6 I;  1K9O I;  2D26 A;  2ARR A;  2OAY A;  2HI9 A;  5CDZ A;  2VDY A;  3STO A;  1OVA A;  2XN3 A;  3F02 A;  1OC0 A;  1AS4 A;  3NDF A;  4AU4 A;  5C98 A;  1IZ2 A;  4CAA A;  1XQJ A;  1IMV A;  3DY0 A;  2WXZ C;  5CE0 A;  4EB1 L;  1DZH L;  7API A;  4ROA A;  1E05 I;  1XU8 A;  2WXW A;  2XN5 A;  4G8R A;  2R9Y A;  2RIV A;  2B5T I;  2XN6 A;  1DZG L;  1E04 I;  4IF8 A;  4ZK3 A;  4AU3 A;  1OO8 A;  2WXY C;  3NDD A;  2ZNH A;  4G8O A;  1PSI A;  4Y3K A;  2OL2 A;  1HLE A;  3NDA A;  2B4X I;  2RIW A;  1YXA A;  4AJT A;  9API A;  8API A;  1DVM A;  1OYH L;  1LQ8 A;  2GD4 C;  2V95 A;  3PB1 I;  4EB1 I;  1OVA B;  4R9I A;  1NQ9 I;  1T1F A;  3DRM A;  3VVJ A;  1OVA C;  1DB2 A;  2ANT I;  4AFX A;  1JJO C;  2ZV6 A;  1C5G A;  2PEF A;  2CEO A;  3CVM A;  3EVJ I;  3CWM A;  1EZX A;  2H4P A;  3UT3 A;  4DY0 A;  1SR5 A;  1WZ9 A;  3F5N A;  2H4Q A;  2HIJ L;  1KCT A;  2ACH A;  3OZQ A;  4AU3 B;  1ATT A;  4PYW A;  3CWL A;  1OPH A;  3LW2 A;  2BEH L;  1JMO A;  1ATU A;  1M93 B;  4KDS A;  1QLP A;  1A7C A;  3FGQ A;  1BR8 I;  1D5S A;  1MTP A; 
#chains in the Genus database with same CATH topology
 2ARQ A;  4YIA A;  1LJ5 A;  4X30 A;  4C49 A;  1DZH I;  3CAA A;  5IO1 A;  3KCG I;  5BRR I;  2H4R A;  3R4L A;  2WXX A;  3NE4 A;  1QMN A;  5HGC A;  1HP7 A;  5CDX A;  1E03 I;  3EOX A;  3LE2 A;  3PZF A;  1DZG I;  4GA7 A;  1R1L I;  3Q02 A;  5EI0 A;  3F1S A;  1QMB A;  4IC0 A;  2HIJ I;  9PAI A;  4RSQ A;  4Y40 A;  2DUT A;  5INW A;  4AU2 A;  4AQH A;  4BB2 A;  4ZK0 A;  1UHG A;  4DTE A;  1SNG A;  3T1P A;  2VH4 A;  2B4X L;  1OYH I;  3DLW A;  4AJU A;  2WXZ A;  3B9F I;  2VDX A;  1JMJ A;  1TB6 I;  4P0O A;  4RO9 A;  1XQG A;  3H5C A;  1B3K A;  1JVQ I;  2QUG A;  4ROB A;  1DVN A;  4DY7 C;  2XN7 A;  3ZHA A;  1JRR A;  4P0F A;  1BY7 A;  2WY1 A;  2WY0 C;  3DRU A;  1ATH A;  1ANT I;  2PEE A;  3Q03 A;  1C8O A;  1AZX I;  4C41 A;  1F0C A;  1SEK A;  2BEH I;  1JTI A;  1LK6 I;  1K9O I;  2D26 A;  2ARR A;  2OAY A;  2HI9 A;  5CDZ A;  2VDY A;  3STO A;  1OVA A;  2XN3 A;  3F02 A;  1OC0 A;  1AS4 A;  3NDF A;  4AU4 A;  5C98 A;  1IZ2 A;  4CAA A;  1XQJ A;  1IMV A;  3DY0 A;  2WXZ C;  5CE0 A;  4EB1 L;  1DZH L;  7API A;  4ROA A;  1E05 I;  1XU8 A;  2WXW A;  2XN5 A;  4G8R A;  2R9Y A;  2RIV A;  2B5T I;  2XN6 A;  1DZG L;  1E04 I;  4IF8 A;  4ZK3 A;  4AU3 A;  1OO8 A;  2WXY C;  3NDD A;  2ZNH A;  4G8O A;  1PSI A;  4Y3K A;  2OL2 A;  1HLE A;  3NDA A;  2B4X I;  2RIW A;  1YXA A;  4AJT A;  9API A;  8API A;  1DVM A;  1OYH L;  1LQ8 A;  2GD4 C;  2V95 A;  3PB1 I;  4EB1 I;  1OVA B;  4R9I A;  1NQ9 I;  1T1F A;  3DRM A;  3VVJ A;  1OVA C;  1DB2 A;  2ANT I;  4AFX A;  1JJO C;  2ZV6 A;  1C5G A;  2PEF A;  2CEO A;  3CVM A;  3EVJ I;  3CWM A;  1EZX A;  2H4P A;  3UT3 A;  4DY0 A;  1SR5 A;  1WZ9 A;  3F5N A;  2H4Q A;  2HIJ L;  1KCT A;  2ACH A;  3OZQ A;  4AU3 B;  1ATT A;  4PYW A;  3CWL A;  1OPH A;  3LW2 A;  2BEH L;  1JMO A;  1ATU A;  1M93 B;  4KDS A;  1QLP A;  1A7C A;  3FGQ A;  1BR8 I;  1D5S A;  1MTP A; 
#chains in the Genus database with same CATH homology
 2ARQ A;  4YIA A;  1LJ5 A;  4X30 A;  4C49 A;  1DZH I;  3CAA A;  5IO1 A;  3KCG I;  5BRR I;  2H4R A;  3R4L A;  2WXX A;  3NE4 A;  1QMN A;  5HGC A;  1HP7 A;  5CDX A;  1E03 I;  3EOX A;  3LE2 A;  3PZF A;  1DZG I;  4GA7 A;  1R1L I;  3Q02 A;  5EI0 A;  3F1S A;  1QMB A;  4IC0 A;  2HIJ I;  9PAI A;  4RSQ A;  4Y40 A;  2DUT A;  5INW A;  4AU2 A;  4AQH A;  4BB2 A;  4ZK0 A;  1UHG A;  4DTE A;  1SNG A;  3T1P A;  2VH4 A;  2B4X L;  1OYH I;  3DLW A;  4AJU A;  2WXZ A;  3B9F I;  2VDX A;  1JMJ A;  1TB6 I;  4P0O A;  4RO9 A;  1XQG A;  3H5C A;  1B3K A;  1JVQ I;  2QUG A;  4ROB A;  1DVN A;  4DY7 C;  2XN7 A;  3ZHA A;  1JRR A;  4P0F A;  1BY7 A;  2WY1 A;  2WY0 C;  3DRU A;  1ATH A;  1ANT I;  2PEE A;  3Q03 A;  1C8O A;  1AZX I;  4C41 A;  1F0C A;  1SEK A;  2BEH I;  1JTI A;  1LK6 I;  1K9O I;  2D26 A;  2ARR A;  2OAY A;  2HI9 A;  5CDZ A;  2VDY A;  3STO A;  1OVA A;  2XN3 A;  3F02 A;  1OC0 A;  1AS4 A;  3NDF A;  4AU4 A;  5C98 A;  1IZ2 A;  4CAA A;  1XQJ A;  1IMV A;  3DY0 A;  2WXZ C;  5CE0 A;  4EB1 L;  1DZH L;  7API A;  4ROA A;  1E05 I;  1XU8 A;  2WXW A;  2XN5 A;  4G8R A;  2R9Y A;  2RIV A;  2B5T I;  2XN6 A;  1DZG L;  1E04 I;  4IF8 A;  4ZK3 A;  4AU3 A;  1OO8 A;  2WXY C;  3NDD A;  2ZNH A;  4G8O A;  1PSI A;  4Y3K A;  2OL2 A;  1HLE A;  3NDA A;  2B4X I;  2RIW A;  1YXA A;  4AJT A;  9API A;  8API A;  1DVM A;  1OYH L;  1LQ8 A;  2GD4 C;  2V95 A;  3PB1 I;  4EB1 I;  1OVA B;  4R9I A;  1NQ9 I;  1T1F A;  3DRM A;  3VVJ A;  1OVA C;  1DB2 A;  2ANT I;  4AFX A;  1JJO C;  2ZV6 A;  1C5G A;  2PEF A;  2CEO A;  3CVM A;  3EVJ I;  3CWM A;  1EZX A;  2H4P A;  3UT3 A;  4DY0 A;  1SR5 A;  1WZ9 A;  3F5N A;  2H4Q A;  2HIJ L;  1KCT A;  2ACH A;  3OZQ A;  4AU3 B;  1ATT A;  4PYW A;  3CWL A;  1OPH A;  3LW2 A;  2BEH L;  1JMO A;  1ATU A;  1M93 B;  4KDS A;  1QLP A;  1A7C A;  3FGQ A;  1BR8 I;  1D5S A;  1MTP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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