2WXYC

Crystal structure of mouse angiotensinogen in the reduced form
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
449
structure length
419
Chain Sequence
RVYIHPFHLLYHNKSTLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTPLLQSIVVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCISDLDRVEALIFQDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
pubmed doi rcsb
molecule tags Hormone
source organism Mus musculus
molecule keywords ANGIOTENSINOGEN
total genus 128
structure length 419
sequence length 449
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2wxyC01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2wxyC02
2R9YA 8APIA 1KCTA 4AJUA 2H4QA 2ARRA 1K9OI 2ZV6A 4EB1L 3STOA 1OVAB 1E03I 4KDSA 2VH4A 3DLWA 3LW2A 2ANTI 1DB2A 1EZXA 1NQ9I 1JRRA 4ROBA 2XN6A 2B4XL 4YIAA 1IMVA 4AU4A 3NDFA 1OVAA 2PEFA 4CAAA 2WXYC 1DZHL 1TB6I 1R1LI 3NDDA 2H4RA 4C49A 2DUTA 1JJOC 3Q03A 2BEHI 1E04I 3DRMA 3PB1I 4ROAA 5INWA 2HI9A 4BB2A 2HIJI 1WZ9A 5EI0A 2VDXA 4AQHA 2XN7A 4Y40A 4IF8A 1ANTI 1PSIA 2WXWA 2OAYA 1HLEA 1HP7A 2ZNHA 3NE4A 3Q02A 5CE0A 4AJTA 3CVMA 1A7CA 2BEHL 4GA7A 3EOXA 3F1SA 4AU3B 2H4PA 4RO9A 1OVAC 5BRRI 4IC0A 4ZK3A 4ZK0A 4Y3KA 2HIJL 3DY0A 1C8OA 2WXZA 4G8OA 1C5GA 3OZQA 3CAAA 2V95A 2PEEA 4AU3A 3ZHAA 5HGCA 1QLPA 1D5SA 2XN3A 1XQGA 3H5CA 1OPHA 3FGQA 1QMNA 1DZGI 1F0CA 3F5NA 2XN5A 1LJ5A 2ARQA 3EVJI 4DY7C 1OC0A 4DTEA 2RIWA 1JMJA 1T1FA 1BR8I 1M93B 1DVMA 9PAIA 2WY0C 3KCGI 3VVJA 1MTPA 1ATTA 2VDYA 5CDXA 1OO8A 4DY0A 1YXAA 3UT3A 2ACHA 1DZGL 9APIA 1JVQI 1XQJA 4P0FA 2WXZC 1SEKA 4R9IA 1E05I 3T1PA 1DVNA 4G8RA 1IZ2A 3CWMA 1OYHI 5CDZA 1BY7A 2B5TI 1AS4A 2GD4C 2OL2A 2D26A 4AU2A 4RSQA 1ATHA 4C41A 1JMOA 1JTIA 4P0OA 2WY1A 5C98A 1LQ8A 1B3KA 4X30A 2CEOA 3CWLA 4EB1I 3PZFA 1XU8A 2WXXA 1ATUA 2RIVA 3F02A 1OYHL 1SR5A 1QMBA 7APIA 1UHGA 1SNGA 3LE2A 2B4XI 3B9FI 4AFXA 3DRUA 1DZHI 4PYWA 3R4LA 2QUGA 5IO1A 3NDAA 1LK6I 1AZXI
chains in the Genus database with same CATH superfamily
2R9YA 8APIA 1KCTA 4AJUA 2H4QA 2ARRA 1K9OI 2ZV6A 4EB1L 3STOA 1OVAB 1E03I 4KDSA 2VH4A 3DLWA 3LW2A 2ANTI 1DB2A 1EZXA 1NQ9I 1JRRA 4ROBA 2XN6A 2B4XL 4YIAA 1IMVA 4AU4A 3NDFA 1OVAA 2PEFA 4CAAA 2WXYC 1DZHL 1TB6I 1R1LI 3NDDA 2H4RA 4C49A 2DUTA 1JJOC 3Q03A 2BEHI 1E04I 3DRMA 3PB1I 4ROAA 5INWA 2HI9A 4BB2A 2HIJI 1WZ9A 5EI0A 2VDXA 4AQHA 2XN7A 4Y40A 4IF8A 1ANTI 1PSIA 2WXWA 2OAYA 1HLEA 1HP7A 2ZNHA 3NE4A 3Q02A 5CE0A 4AJTA 3CVMA 1A7CA 2BEHL 4GA7A 3EOXA 3F1SA 4AU3B 2H4PA 4RO9A 1OVAC 5BRRI 4IC0A 4ZK3A 4ZK0A 4Y3KA 2HIJL 3DY0A 1C8OA 2WXZA 4G8OA 1C5GA 3OZQA 3CAAA 2V95A 2PEEA 4AU3A 3ZHAA 5HGCA 1QLPA 1D5SA 2XN3A 1XQGA 3H5CA 1OPHA 3FGQA 1QMNA 1DZGI 1F0CA 3F5NA 2XN5A 1LJ5A 2ARQA 3EVJI 4DY7C 1OC0A 4DTEA 2RIWA 1JMJA 1T1FA 1BR8I 1M93B 1DVMA 9PAIA 2WY0C 3KCGI 3VVJA 1MTPA 1ATTA 2VDYA 5CDXA 1OO8A 4DY0A 1YXAA 3UT3A 2ACHA 1DZGL 9APIA 1JVQI 1XQJA 4P0FA 2WXZC 1SEKA 4R9IA 1E05I 3T1PA 1DVNA 4G8RA 1IZ2A 3CWMA 1OYHI 5CDZA 1BY7A 2B5TI 1AS4A 2GD4C 2OL2A 2D26A 4AU2A 4RSQA 1ATHA 4C41A 1JMOA 1JTIA 4P0OA 2WY1A 5C98A 1LQ8A 1B3KA 4X30A 2CEOA 3CWLA 4EB1I 3PZFA 1XU8A 2WXXA 1ATUA 2RIVA 3F02A 1OYHL 1SR5A 1QMBA 7APIA 1UHGA 1SNGA 3LE2A 2B4XI 3B9FI 4AFXA 3DRUA 1DZHI 4PYWA 3R4LA 2QUGA 5IO1A 3NDAA 1LK6I 1AZXI
chains in the Genus database with same CATH topology
2R9YA 8APIA 1KCTA 4AJUA 2H4QA 2ARRA 1K9OI 2ZV6A 4EB1L 3STOA 1OVAB 1E03I 4KDSA 2VH4A 3DLWA 3LW2A 2ANTI 1DB2A 1EZXA 1NQ9I 1JRRA 4ROBA 2XN6A 2B4XL 4YIAA 1IMVA 4AU4A 3NDFA 1OVAA 2PEFA 4CAAA 2WXYC 1DZHL 1TB6I 1R1LI 3NDDA 2H4RA 4C49A 2DUTA 1JJOC 3Q03A 2BEHI 1E04I 3DRMA 3PB1I 4ROAA 5INWA 2HI9A 4BB2A 2HIJI 1WZ9A 5EI0A 2VDXA 4AQHA 2XN7A 4Y40A 4IF8A 1ANTI 1PSIA 2WXWA 2OAYA 1HLEA 1HP7A 2ZNHA 3NE4A 3Q02A 5CE0A 4AJTA 3CVMA 1A7CA 2BEHL 4GA7A 3EOXA 3F1SA 4AU3B 2H4PA 4RO9A 1OVAC 5BRRI 4IC0A 4ZK3A 4ZK0A 4Y3KA 2HIJL 3DY0A 1C8OA 2WXZA 4G8OA 1C5GA 3OZQA 3CAAA 2V95A 2PEEA 4AU3A 3ZHAA 5HGCA 1QLPA 1D5SA 2XN3A 1XQGA 3H5CA 1OPHA 3FGQA 1QMNA 1DZGI 1F0CA 3F5NA 2XN5A 1LJ5A 2ARQA 3EVJI 4DY7C 1OC0A 4DTEA 2RIWA 1JMJA 1T1FA 1BR8I 1M93B 1DVMA 9PAIA 2WY0C 3KCGI 3VVJA 1MTPA 1ATTA 2VDYA 5CDXA 1OO8A 4DY0A 1YXAA 3UT3A 2ACHA 1DZGL 9APIA 1JVQI 1XQJA 4P0FA 2WXZC 1SEKA 4R9IA 1E05I 3T1PA 1DVNA 4G8RA 1IZ2A 3CWMA 1OYHI 5CDZA 1BY7A 2B5TI 1AS4A 2GD4C 2OL2A 2D26A 4AU2A 4RSQA 1ATHA 4C41A 1JMOA 1JTIA 4P0OA 2WY1A 5C98A 1LQ8A 1B3KA 4X30A 2CEOA 3CWLA 4EB1I 3PZFA 1XU8A 2WXXA 1ATUA 2RIVA 3F02A 1OYHL 1SR5A 1QMBA 7APIA 1UHGA 1SNGA 3LE2A 2B4XI 3B9FI 4AFXA 3DRUA 1DZHI 4PYWA 3R4LA 2QUGA 5IO1A 3NDAA 1LK6I 1AZXI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R9Y A;  8API A;  1KCT A;  4AJU A;  2H4Q A;  2ARR A;  1K9O I;  2ZV6 A;  4EB1 L;  3STO A;  1OVA B;  1E03 I;  4KDS A;  2VH4 A;  3DLW A;  3LW2 A;  2ANT I;  1DB2 A;  1EZX A;  1NQ9 I;  1JRR A;  4ROB A;  2XN6 A;  2B4X L;  4YIA A;  1IMV A;  4AU4 A;  3NDF A;  1OVA A;  2PEF A;  4CAA A;  2WXY C;  1DZH L;  1TB6 I;  1R1L I;  3NDD A;  2H4R A;  4C49 A;  2DUT A;  1JJO C;  3Q03 A;  2BEH I;  1E04 I;  3DRM A;  3PB1 I;  4ROA A;  5INW A;  2HI9 A;  4BB2 A;  2HIJ I;  1WZ9 A;  5EI0 A;  2VDX A;  4AQH A;  2XN7 A;  4Y40 A;  4IF8 A;  1ANT I;  1PSI A;  2WXW A;  2OAY A;  1HLE A;  1HP7 A;  2ZNH A;  3NE4 A;  3Q02 A;  5CE0 A;  4AJT A;  3CVM A;  1A7C A;  2BEH L;  4GA7 A;  3EOX A;  3F1S A;  4AU3 B;  2H4P A;  4RO9 A;  1OVA C;  5BRR I;  4IC0 A;  4ZK3 A;  4ZK0 A;  4Y3K A;  2HIJ L;  3DY0 A;  1C8O A;  2WXZ A;  4G8O A;  1C5G A;  3OZQ A;  3CAA A;  2V95 A;  2PEE A;  4AU3 A;  3ZHA A;  5HGC A;  1QLP A;  1D5S A;  2XN3 A;  1XQG A;  3H5C A;  1OPH A;  3FGQ A;  1QMN A;  1DZG I;  1F0C A;  3F5N A;  2XN5 A;  1LJ5 A;  2ARQ A;  3EVJ I;  4DY7 C;  1OC0 A;  4DTE A;  2RIW A;  1JMJ A;  1T1F A;  1BR8 I;  1M93 B;  1DVM A;  9PAI A;  2WY0 C;  3KCG I;  3VVJ A;  1MTP A;  1ATT A;  2VDY A;  5CDX A;  1OO8 A;  4DY0 A;  1YXA A;  3UT3 A;  2ACH A;  1DZG L;  9API A;  1JVQ I;  1XQJ A;  4P0F A;  2WXZ C;  1SEK A;  4R9I A;  1E05 I;  3T1P A;  1DVN A;  4G8R A;  1IZ2 A;  3CWM A;  1OYH I;  5CDZ A;  1BY7 A;  2B5T I;  1AS4 A;  2GD4 C;  2OL2 A;  2D26 A;  4AU2 A;  4RSQ A;  1ATH A;  4C41 A;  1JMO A;  1JTI A;  4P0O A;  2WY1 A;  5C98 A;  1LQ8 A;  1B3K A;  4X30 A;  2CEO A;  3CWL A;  4EB1 I;  3PZF A;  1XU8 A;  2WXX A;  1ATU A;  2RIV A;  3F02 A;  1OYH L;  1SR5 A;  1QMB A;  7API A;  1UHG A;  1SNG A;  3LE2 A;  2B4X I;  3B9F I;  4AFX A;  3DRU A;  1DZH I;  4PYW A;  3R4L A;  2QUG A;  5IO1 A;  3NDA A;  1LK6 I;  1AZX I; 
#chains in the Genus database with same CATH topology
 2R9Y A;  8API A;  1KCT A;  4AJU A;  2H4Q A;  2ARR A;  1K9O I;  2ZV6 A;  4EB1 L;  3STO A;  1OVA B;  1E03 I;  4KDS A;  2VH4 A;  3DLW A;  3LW2 A;  2ANT I;  1DB2 A;  1EZX A;  1NQ9 I;  1JRR A;  4ROB A;  2XN6 A;  2B4X L;  4YIA A;  1IMV A;  4AU4 A;  3NDF A;  1OVA A;  2PEF A;  4CAA A;  2WXY C;  1DZH L;  1TB6 I;  1R1L I;  3NDD A;  2H4R A;  4C49 A;  2DUT A;  1JJO C;  3Q03 A;  2BEH I;  1E04 I;  3DRM A;  3PB1 I;  4ROA A;  5INW A;  2HI9 A;  4BB2 A;  2HIJ I;  1WZ9 A;  5EI0 A;  2VDX A;  4AQH A;  2XN7 A;  4Y40 A;  4IF8 A;  1ANT I;  1PSI A;  2WXW A;  2OAY A;  1HLE A;  1HP7 A;  2ZNH A;  3NE4 A;  3Q02 A;  5CE0 A;  4AJT A;  3CVM A;  1A7C A;  2BEH L;  4GA7 A;  3EOX A;  3F1S A;  4AU3 B;  2H4P A;  4RO9 A;  1OVA C;  5BRR I;  4IC0 A;  4ZK3 A;  4ZK0 A;  4Y3K A;  2HIJ L;  3DY0 A;  1C8O A;  2WXZ A;  4G8O A;  1C5G A;  3OZQ A;  3CAA A;  2V95 A;  2PEE A;  4AU3 A;  3ZHA A;  5HGC A;  1QLP A;  1D5S A;  2XN3 A;  1XQG A;  3H5C A;  1OPH A;  3FGQ A;  1QMN A;  1DZG I;  1F0C A;  3F5N A;  2XN5 A;  1LJ5 A;  2ARQ A;  3EVJ I;  4DY7 C;  1OC0 A;  4DTE A;  2RIW A;  1JMJ A;  1T1F A;  1BR8 I;  1M93 B;  1DVM A;  9PAI A;  2WY0 C;  3KCG I;  3VVJ A;  1MTP A;  1ATT A;  2VDY A;  5CDX A;  1OO8 A;  4DY0 A;  1YXA A;  3UT3 A;  2ACH A;  1DZG L;  9API A;  1JVQ I;  1XQJ A;  4P0F A;  2WXZ C;  1SEK A;  4R9I A;  1E05 I;  3T1P A;  1DVN A;  4G8R A;  1IZ2 A;  3CWM A;  1OYH I;  5CDZ A;  1BY7 A;  2B5T I;  1AS4 A;  2GD4 C;  2OL2 A;  2D26 A;  4AU2 A;  4RSQ A;  1ATH A;  4C41 A;  1JMO A;  1JTI A;  4P0O A;  2WY1 A;  5C98 A;  1LQ8 A;  1B3K A;  4X30 A;  2CEO A;  3CWL A;  4EB1 I;  3PZF A;  1XU8 A;  2WXX A;  1ATU A;  2RIV A;  3F02 A;  1OYH L;  1SR5 A;  1QMB A;  7API A;  1UHG A;  1SNG A;  3LE2 A;  2B4X I;  3B9F I;  4AFX A;  3DRU A;  1DZH I;  4PYW A;  3R4L A;  2QUG A;  5IO1 A;  3NDA A;  1LK6 I;  1AZX I; 
#chains in the Genus database with same CATH homology
 2R9Y A;  8API A;  1KCT A;  4AJU A;  2H4Q A;  2ARR A;  1K9O I;  2ZV6 A;  4EB1 L;  3STO A;  1OVA B;  1E03 I;  4KDS A;  2VH4 A;  3DLW A;  3LW2 A;  2ANT I;  1DB2 A;  1EZX A;  1NQ9 I;  1JRR A;  4ROB A;  2XN6 A;  2B4X L;  4YIA A;  1IMV A;  4AU4 A;  3NDF A;  1OVA A;  2PEF A;  4CAA A;  2WXY C;  1DZH L;  1TB6 I;  1R1L I;  3NDD A;  2H4R A;  4C49 A;  2DUT A;  1JJO C;  3Q03 A;  2BEH I;  1E04 I;  3DRM A;  3PB1 I;  4ROA A;  5INW A;  2HI9 A;  4BB2 A;  2HIJ I;  1WZ9 A;  5EI0 A;  2VDX A;  4AQH A;  2XN7 A;  4Y40 A;  4IF8 A;  1ANT I;  1PSI A;  2WXW A;  2OAY A;  1HLE A;  1HP7 A;  2ZNH A;  3NE4 A;  3Q02 A;  5CE0 A;  4AJT A;  3CVM A;  1A7C A;  2BEH L;  4GA7 A;  3EOX A;  3F1S A;  4AU3 B;  2H4P A;  4RO9 A;  1OVA C;  5BRR I;  4IC0 A;  4ZK3 A;  4ZK0 A;  4Y3K A;  2HIJ L;  3DY0 A;  1C8O A;  2WXZ A;  4G8O A;  1C5G A;  3OZQ A;  3CAA A;  2V95 A;  2PEE A;  4AU3 A;  3ZHA A;  5HGC A;  1QLP A;  1D5S A;  2XN3 A;  1XQG A;  3H5C A;  1OPH A;  3FGQ A;  1QMN A;  1DZG I;  1F0C A;  3F5N A;  2XN5 A;  1LJ5 A;  2ARQ A;  3EVJ I;  4DY7 C;  1OC0 A;  4DTE A;  2RIW A;  1JMJ A;  1T1F A;  1BR8 I;  1M93 B;  1DVM A;  9PAI A;  2WY0 C;  3KCG I;  3VVJ A;  1MTP A;  1ATT A;  2VDY A;  5CDX A;  1OO8 A;  4DY0 A;  1YXA A;  3UT3 A;  2ACH A;  1DZG L;  9API A;  1JVQ I;  1XQJ A;  4P0F A;  2WXZ C;  1SEK A;  4R9I A;  1E05 I;  3T1P A;  1DVN A;  4G8R A;  1IZ2 A;  3CWM A;  1OYH I;  5CDZ A;  1BY7 A;  2B5T I;  1AS4 A;  2GD4 C;  2OL2 A;  2D26 A;  4AU2 A;  4RSQ A;  1ATH A;  4C41 A;  1JMO A;  1JTI A;  4P0O A;  2WY1 A;  5C98 A;  1LQ8 A;  1B3K A;  4X30 A;  2CEO A;  3CWL A;  4EB1 I;  3PZF A;  1XU8 A;  2WXX A;  1ATU A;  2RIV A;  3F02 A;  1OYH L;  1SR5 A;  1QMB A;  7API A;  1UHG A;  1SNG A;  3LE2 A;  2B4X I;  3B9F I;  4AFX A;  3DRU A;  1DZH I;  4PYW A;  3R4L A;  2QUG A;  5IO1 A;  3NDA A;  1LK6 I;  1AZX I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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