2WXZA

Crystal structure of rat angiotensinogen in c2 space group
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
445
structure length
422
Chain Sequence
HPFHLLYYSKSTCAQTLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFVGFRMYKMLSEARVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
pubmed doi rcsb
molecule tags Hormone
source organism Rattus norvegicus
molecule keywords ANGIOTENSINOGEN
total genus 105
structure length 422
sequence length 445
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2wxzA01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2wxzA02
3UT3A 1LJ5A 1E04I 1LK6I 3VVJA 2XN5A 2B5TI 4YIAA 1EZXA 3PB1I 1D5SA 1C5GA 3Q02A 4AJUA 1A7CA 1OVAC 1C8OA 2HIJI 3DRUA 2BEHL 2B4XL 3ZHAA 4AFXA 4EB1L 1YXAA 2D26A 4CAAA 3T1PA 3LW2A 8APIA 1NQ9I 3STOA 3NDFA 2WXWA 3B9FI 4ZK3A 3F02A 4AQHA 2BEHI 2RIVA 1JRRA 1E03I 2OL2A 4DY0A 1F0CA 1IZ2A 2PEFA 3NDAA 4EB1I 4DTEA 1ATTA 4C49A 5CDZA 4ROBA 4AU3A 1R1LI 2PEEA 2QUGA 1DZHL 1LQ8A 1OYHL 4C41A 4GA7A 2XN3A 3FGQA 4P0OA 4IF8A 2VDYA 5CE0A 4ZK0A 1DVNA 1JMJA 2WXYC 1UHGA 2ACHA 2ARRA 1DZHI 1OYHI 1KCTA 3DLWA 1MTPA 4X30A 3KCGI 1SNGA 4G8OA 3F1SA 1E05I 2B4XI 4RSQA 2H4RA 4G8RA 1JJOC 1AS4A 1XQGA 2H4PA 3F5NA 2GD4C 5BRRI 2WXZA 3EVJI 4PYWA 5EI0A 1OVAA 4IC0A 3PZFA 2ZNHA 2XN7A 4AU3B 2ZV6A 1T1FA 1XQJA 5HGCA 4BB2A 1DZGL 1AZXI 2HIJL 3Q03A 3CAAA 4R9IA 4Y3KA 9PAIA 2DUTA 3DRMA 4DY7C 5INWA 1ATHA 1OC0A 1TB6I 3NDDA 2XN6A 2VH4A 2ARQA 2OAYA 4ROAA 1DVMA 3LE2A 4RO9A 1SEKA 2WXZC 1BR8I 4AJTA 1JVQI 1SR5A 2WY0C 7APIA 3CWLA 1OPHA 1DZGI 1ATUA 1HP7A 1QMBA 1JMOA 1HLEA 4AU2A 1PSIA 2CEOA 1OO8A 2R9YA 9APIA 1B3KA 3H5CA 1DB2A 5IO1A 5C98A 2ANTI 3CWMA 2H4QA 1QLPA 1IMVA 2VDXA 2WY1A 3CVMA 1BY7A 1M93B 3OZQA 1ANTI 4Y40A 3R4LA 2HI9A 4AU4A 1WZ9A 3EOXA 1QMNA 3DY0A 3NE4A 4KDSA 1OVAB 4P0FA 2RIWA 1K9OI 2V95A 1XU8A 2WXXA 1JTIA 5CDXA
chains in the Genus database with same CATH superfamily
3UT3A 1LJ5A 1E04I 1LK6I 3VVJA 2XN5A 2B5TI 4YIAA 1EZXA 3PB1I 1D5SA 1C5GA 3Q02A 4AJUA 1A7CA 1OVAC 1C8OA 2HIJI 3DRUA 2BEHL 2B4XL 3ZHAA 4AFXA 4EB1L 1YXAA 2D26A 4CAAA 3T1PA 3LW2A 8APIA 1NQ9I 3STOA 3NDFA 2WXWA 3B9FI 4ZK3A 3F02A 4AQHA 2BEHI 2RIVA 1JRRA 1E03I 2OL2A 4DY0A 1F0CA 1IZ2A 2PEFA 3NDAA 4EB1I 4DTEA 1ATTA 4C49A 5CDZA 4ROBA 4AU3A 1R1LI 2PEEA 2QUGA 1DZHL 1LQ8A 1OYHL 4C41A 4GA7A 2XN3A 3FGQA 4P0OA 4IF8A 2VDYA 5CE0A 4ZK0A 1DVNA 1JMJA 2WXYC 1UHGA 2ACHA 2ARRA 1DZHI 1OYHI 1KCTA 3DLWA 1MTPA 4X30A 3KCGI 1SNGA 4G8OA 3F1SA 1E05I 2B4XI 4RSQA 2H4RA 4G8RA 1JJOC 1AS4A 1XQGA 2H4PA 3F5NA 2GD4C 5BRRI 2WXZA 3EVJI 4PYWA 5EI0A 1OVAA 4IC0A 3PZFA 2ZNHA 2XN7A 4AU3B 2ZV6A 1T1FA 1XQJA 5HGCA 4BB2A 1DZGL 1AZXI 2HIJL 3Q03A 3CAAA 4R9IA 4Y3KA 9PAIA 2DUTA 3DRMA 4DY7C 5INWA 1ATHA 1OC0A 1TB6I 3NDDA 2XN6A 2VH4A 2ARQA 2OAYA 4ROAA 1DVMA 3LE2A 4RO9A 1SEKA 2WXZC 1BR8I 4AJTA 1JVQI 1SR5A 2WY0C 7APIA 3CWLA 1OPHA 1DZGI 1ATUA 1HP7A 1QMBA 1JMOA 1HLEA 4AU2A 1PSIA 2CEOA 1OO8A 2R9YA 9APIA 1B3KA 3H5CA 1DB2A 5IO1A 5C98A 2ANTI 3CWMA 2H4QA 1QLPA 1IMVA 2VDXA 2WY1A 3CVMA 1BY7A 1M93B 3OZQA 1ANTI 4Y40A 3R4LA 2HI9A 4AU4A 1WZ9A 3EOXA 1QMNA 3DY0A 3NE4A 4KDSA 1OVAB 4P0FA 2RIWA 1K9OI 2V95A 1XU8A 2WXXA 1JTIA 5CDXA
chains in the Genus database with same CATH topology
3UT3A 1LJ5A 1E04I 1LK6I 3VVJA 2XN5A 2B5TI 4YIAA 1EZXA 3PB1I 1D5SA 1C5GA 3Q02A 4AJUA 1A7CA 1OVAC 1C8OA 2HIJI 3DRUA 2BEHL 2B4XL 3ZHAA 4AFXA 4EB1L 1YXAA 2D26A 4CAAA 3T1PA 3LW2A 8APIA 1NQ9I 3STOA 3NDFA 2WXWA 3B9FI 4ZK3A 3F02A 4AQHA 2BEHI 2RIVA 1JRRA 1E03I 2OL2A 4DY0A 1F0CA 1IZ2A 2PEFA 3NDAA 4EB1I 4DTEA 1ATTA 4C49A 5CDZA 4ROBA 4AU3A 1R1LI 2PEEA 2QUGA 1DZHL 1LQ8A 1OYHL 4C41A 4GA7A 2XN3A 3FGQA 4P0OA 4IF8A 2VDYA 5CE0A 4ZK0A 1DVNA 1JMJA 2WXYC 1UHGA 2ACHA 2ARRA 1DZHI 1OYHI 1KCTA 3DLWA 1MTPA 4X30A 3KCGI 1SNGA 4G8OA 3F1SA 1E05I 2B4XI 4RSQA 2H4RA 4G8RA 1JJOC 1AS4A 1XQGA 2H4PA 3F5NA 2GD4C 5BRRI 2WXZA 3EVJI 4PYWA 5EI0A 1OVAA 4IC0A 3PZFA 2ZNHA 2XN7A 4AU3B 2ZV6A 1T1FA 1XQJA 5HGCA 4BB2A 1DZGL 1AZXI 2HIJL 3Q03A 3CAAA 4R9IA 4Y3KA 9PAIA 2DUTA 3DRMA 4DY7C 5INWA 1ATHA 1OC0A 1TB6I 3NDDA 2XN6A 2VH4A 2ARQA 2OAYA 4ROAA 1DVMA 3LE2A 4RO9A 1SEKA 2WXZC 1BR8I 4AJTA 1JVQI 1SR5A 2WY0C 7APIA 3CWLA 1OPHA 1DZGI 1ATUA 1HP7A 1QMBA 1JMOA 1HLEA 4AU2A 1PSIA 2CEOA 1OO8A 2R9YA 9APIA 1B3KA 3H5CA 1DB2A 5IO1A 5C98A 2ANTI 3CWMA 2H4QA 1QLPA 1IMVA 2VDXA 2WY1A 3CVMA 1BY7A 1M93B 3OZQA 1ANTI 4Y40A 3R4LA 2HI9A 4AU4A 1WZ9A 3EOXA 1QMNA 3DY0A 3NE4A 4KDSA 1OVAB 4P0FA 2RIWA 1K9OI 2V95A 1XU8A 2WXXA 1JTIA 5CDXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UT3 A;  1LJ5 A;  1E04 I;  1LK6 I;  3VVJ A;  2XN5 A;  2B5T I;  4YIA A;  1EZX A;  3PB1 I;  1D5S A;  1C5G A;  3Q02 A;  4AJU A;  1A7C A;  1OVA C;  1C8O A;  2HIJ I;  3DRU A;  2BEH L;  2B4X L;  3ZHA A;  4AFX A;  4EB1 L;  1YXA A;  2D26 A;  4CAA A;  3T1P A;  3LW2 A;  8API A;  1NQ9 I;  3STO A;  3NDF A;  2WXW A;  3B9F I;  4ZK3 A;  3F02 A;  4AQH A;  2BEH I;  2RIV A;  1JRR A;  1E03 I;  2OL2 A;  4DY0 A;  1F0C A;  1IZ2 A;  2PEF A;  3NDA A;  4EB1 I;  4DTE A;  1ATT A;  4C49 A;  5CDZ A;  4ROB A;  4AU3 A;  1R1L I;  2PEE A;  2QUG A;  1DZH L;  1LQ8 A;  1OYH L;  4C41 A;  4GA7 A;  2XN3 A;  3FGQ A;  4P0O A;  4IF8 A;  2VDY A;  5CE0 A;  4ZK0 A;  1DVN A;  1JMJ A;  2WXY C;  1UHG A;  2ACH A;  2ARR A;  1DZH I;  1OYH I;  1KCT A;  3DLW A;  1MTP A;  4X30 A;  3KCG I;  1SNG A;  4G8O A;  3F1S A;  1E05 I;  2B4X I;  4RSQ A;  2H4R A;  4G8R A;  1JJO C;  1AS4 A;  1XQG A;  2H4P A;  3F5N A;  2GD4 C;  5BRR I;  2WXZ A;  3EVJ I;  4PYW A;  5EI0 A;  1OVA A;  4IC0 A;  3PZF A;  2ZNH A;  2XN7 A;  4AU3 B;  2ZV6 A;  1T1F A;  1XQJ A;  5HGC A;  4BB2 A;  1DZG L;  1AZX I;  2HIJ L;  3Q03 A;  3CAA A;  4R9I A;  4Y3K A;  9PAI A;  2DUT A;  3DRM A;  4DY7 C;  5INW A;  1ATH A;  1OC0 A;  1TB6 I;  3NDD A;  2XN6 A;  2VH4 A;  2ARQ A;  2OAY A;  4ROA A;  1DVM A;  3LE2 A;  4RO9 A;  1SEK A;  2WXZ C;  1BR8 I;  4AJT A;  1JVQ I;  1SR5 A;  2WY0 C;  7API A;  3CWL A;  1OPH A;  1DZG I;  1ATU A;  1HP7 A;  1QMB A;  1JMO A;  1HLE A;  4AU2 A;  1PSI A;  2CEO A;  1OO8 A;  2R9Y A;  9API A;  1B3K A;  3H5C A;  1DB2 A;  5IO1 A;  5C98 A;  2ANT I;  3CWM A;  2H4Q A;  1QLP A;  1IMV A;  2VDX A;  2WY1 A;  3CVM A;  1BY7 A;  1M93 B;  3OZQ A;  1ANT I;  4Y40 A;  3R4L A;  2HI9 A;  4AU4 A;  1WZ9 A;  3EOX A;  1QMN A;  3DY0 A;  3NE4 A;  4KDS A;  1OVA B;  4P0F A;  2RIW A;  1K9O I;  2V95 A;  1XU8 A;  2WXX A;  1JTI A;  5CDX A; 
#chains in the Genus database with same CATH topology
 3UT3 A;  1LJ5 A;  1E04 I;  1LK6 I;  3VVJ A;  2XN5 A;  2B5T I;  4YIA A;  1EZX A;  3PB1 I;  1D5S A;  1C5G A;  3Q02 A;  4AJU A;  1A7C A;  1OVA C;  1C8O A;  2HIJ I;  3DRU A;  2BEH L;  2B4X L;  3ZHA A;  4AFX A;  4EB1 L;  1YXA A;  2D26 A;  4CAA A;  3T1P A;  3LW2 A;  8API A;  1NQ9 I;  3STO A;  3NDF A;  2WXW A;  3B9F I;  4ZK3 A;  3F02 A;  4AQH A;  2BEH I;  2RIV A;  1JRR A;  1E03 I;  2OL2 A;  4DY0 A;  1F0C A;  1IZ2 A;  2PEF A;  3NDA A;  4EB1 I;  4DTE A;  1ATT A;  4C49 A;  5CDZ A;  4ROB A;  4AU3 A;  1R1L I;  2PEE A;  2QUG A;  1DZH L;  1LQ8 A;  1OYH L;  4C41 A;  4GA7 A;  2XN3 A;  3FGQ A;  4P0O A;  4IF8 A;  2VDY A;  5CE0 A;  4ZK0 A;  1DVN A;  1JMJ A;  2WXY C;  1UHG A;  2ACH A;  2ARR A;  1DZH I;  1OYH I;  1KCT A;  3DLW A;  1MTP A;  4X30 A;  3KCG I;  1SNG A;  4G8O A;  3F1S A;  1E05 I;  2B4X I;  4RSQ A;  2H4R A;  4G8R A;  1JJO C;  1AS4 A;  1XQG A;  2H4P A;  3F5N A;  2GD4 C;  5BRR I;  2WXZ A;  3EVJ I;  4PYW A;  5EI0 A;  1OVA A;  4IC0 A;  3PZF A;  2ZNH A;  2XN7 A;  4AU3 B;  2ZV6 A;  1T1F A;  1XQJ A;  5HGC A;  4BB2 A;  1DZG L;  1AZX I;  2HIJ L;  3Q03 A;  3CAA A;  4R9I A;  4Y3K A;  9PAI A;  2DUT A;  3DRM A;  4DY7 C;  5INW A;  1ATH A;  1OC0 A;  1TB6 I;  3NDD A;  2XN6 A;  2VH4 A;  2ARQ A;  2OAY A;  4ROA A;  1DVM A;  3LE2 A;  4RO9 A;  1SEK A;  2WXZ C;  1BR8 I;  4AJT A;  1JVQ I;  1SR5 A;  2WY0 C;  7API A;  3CWL A;  1OPH A;  1DZG I;  1ATU A;  1HP7 A;  1QMB A;  1JMO A;  1HLE A;  4AU2 A;  1PSI A;  2CEO A;  1OO8 A;  2R9Y A;  9API A;  1B3K A;  3H5C A;  1DB2 A;  5IO1 A;  5C98 A;  2ANT I;  3CWM A;  2H4Q A;  1QLP A;  1IMV A;  2VDX A;  2WY1 A;  3CVM A;  1BY7 A;  1M93 B;  3OZQ A;  1ANT I;  4Y40 A;  3R4L A;  2HI9 A;  4AU4 A;  1WZ9 A;  3EOX A;  1QMN A;  3DY0 A;  3NE4 A;  4KDS A;  1OVA B;  4P0F A;  2RIW A;  1K9O I;  2V95 A;  1XU8 A;  2WXX A;  1JTI A;  5CDX A; 
#chains in the Genus database with same CATH homology
 3UT3 A;  1LJ5 A;  1E04 I;  1LK6 I;  3VVJ A;  2XN5 A;  2B5T I;  4YIA A;  1EZX A;  3PB1 I;  1D5S A;  1C5G A;  3Q02 A;  4AJU A;  1A7C A;  1OVA C;  1C8O A;  2HIJ I;  3DRU A;  2BEH L;  2B4X L;  3ZHA A;  4AFX A;  4EB1 L;  1YXA A;  2D26 A;  4CAA A;  3T1P A;  3LW2 A;  8API A;  1NQ9 I;  3STO A;  3NDF A;  2WXW A;  3B9F I;  4ZK3 A;  3F02 A;  4AQH A;  2BEH I;  2RIV A;  1JRR A;  1E03 I;  2OL2 A;  4DY0 A;  1F0C A;  1IZ2 A;  2PEF A;  3NDA A;  4EB1 I;  4DTE A;  1ATT A;  4C49 A;  5CDZ A;  4ROB A;  4AU3 A;  1R1L I;  2PEE A;  2QUG A;  1DZH L;  1LQ8 A;  1OYH L;  4C41 A;  4GA7 A;  2XN3 A;  3FGQ A;  4P0O A;  4IF8 A;  2VDY A;  5CE0 A;  4ZK0 A;  1DVN A;  1JMJ A;  2WXY C;  1UHG A;  2ACH A;  2ARR A;  1DZH I;  1OYH I;  1KCT A;  3DLW A;  1MTP A;  4X30 A;  3KCG I;  1SNG A;  4G8O A;  3F1S A;  1E05 I;  2B4X I;  4RSQ A;  2H4R A;  4G8R A;  1JJO C;  1AS4 A;  1XQG A;  2H4P A;  3F5N A;  2GD4 C;  5BRR I;  2WXZ A;  3EVJ I;  4PYW A;  5EI0 A;  1OVA A;  4IC0 A;  3PZF A;  2ZNH A;  2XN7 A;  4AU3 B;  2ZV6 A;  1T1F A;  1XQJ A;  5HGC A;  4BB2 A;  1DZG L;  1AZX I;  2HIJ L;  3Q03 A;  3CAA A;  4R9I A;  4Y3K A;  9PAI A;  2DUT A;  3DRM A;  4DY7 C;  5INW A;  1ATH A;  1OC0 A;  1TB6 I;  3NDD A;  2XN6 A;  2VH4 A;  2ARQ A;  2OAY A;  4ROA A;  1DVM A;  3LE2 A;  4RO9 A;  1SEK A;  2WXZ C;  1BR8 I;  4AJT A;  1JVQ I;  1SR5 A;  2WY0 C;  7API A;  3CWL A;  1OPH A;  1DZG I;  1ATU A;  1HP7 A;  1QMB A;  1JMO A;  1HLE A;  4AU2 A;  1PSI A;  2CEO A;  1OO8 A;  2R9Y A;  9API A;  1B3K A;  3H5C A;  1DB2 A;  5IO1 A;  5C98 A;  2ANT I;  3CWM A;  2H4Q A;  1QLP A;  1IMV A;  2VDX A;  2WY1 A;  3CVM A;  1BY7 A;  1M93 B;  3OZQ A;  1ANT I;  4Y40 A;  3R4L A;  2HI9 A;  4AU4 A;  1WZ9 A;  3EOX A;  1QMN A;  3DY0 A;  3NE4 A;  4KDS A;  1OVA B;  4P0F A;  2RIW A;  1K9O I;  2V95 A;  1XU8 A;  2WXX A;  1JTI A;  5CDX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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