2DUTA

Crystal structure of a m-loop deletion variant of ment in the native conformation
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
382
structure length
366
Chain Sequence
MEQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFIHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLKNKSKPVKMMYMRDTFPVLIMEKMNFKMIELPYVKRELSMFILLPDDTGLEQLERELTYERLSEWADSKMMTETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDLAISKVIHQSFVAVDEKGTEAAAATAVIISFTTSVHVLKFKVDHPFHFFIRHNKSKTILFFGRFCCPVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Gallus gallus
molecule keywords Heterochromatin-associated protein MENT
total genus 85
structure length 366
sequence length 382
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2006-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2dutA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2dutA01
1ATHA 1WZ9A 4Y40A 2B4XL 2HIJL 2ARQA 5HGCA 4DY0A 2ARRA 2B5TI 4BB2A 4AU3B 3VVJA 3KCGI 1IMVA 2VDYA 1LQ8A 3CVMA 4IC0A 4ZK3A 1DZGI 5CDZA 8APIA 3T1PA 1JMOA 1DVNA 1OO8A 2XN3A 1ATUA 1JRRA 1MTPA 1UHGA 2VDXA 2HIJI 4KDSA 5BRRI 4Y3KA 1JTIA 1T1FA 1DVMA 2ZNHA 1BR8I 2H4RA 1F0CA 1NQ9I 1XQJA 3B9FI 2ZV6A 4ROAA 4RSQA 1OPHA 1QMBA 1B3KA 1TB6I 1HP7A 3Q03A 1LK6I 4C49A 1C5GA 3F02A 2WXWA 3NE4A 2HI9A 2ACHA 1E03I 1JMJA 2WY0C 1XU8A 4AJTA 2D26A 1D5SA 1QMNA 3NDDA 7APIA 2WXXA 3NDFA 2B4XI 1AZXI 2XN5A 9APIA 4AFXA 1BY7A 2PEFA 2WY1A 2H4PA 2H4QA 2QUGA 2GD4C 1AS4A 3F1SA 2RIWA 2CEOA 4DY7C 3CWLA 9PAIA 4G8RA 1OVAB 1OVAC 1KCTA 3LE2A 2RIVA 3R4LA 4AU3A 3UT3A 4CAAA 2R9YA 1M93B 4AJUA 3STOA 1JVQI 5C98A 3DRUA 4IF8A 4ROBA 1IZ2A 5CDXA 1EZXA 4R9IA 3PB1I 4DTEA 1PSIA 4AU2A 1ANTI 1DZHL 1R1LI 2DUTA 3DY0A 3OZQA 5INWA 1HLEA 4P0OA 2ANTI 4YIAA 3LW2A 5EI0A 1E04I 2WXZA 4RO9A 4EB1L 1LJ5A 1OYHL 1K9OI 3PZFA 4C41A 3CWMA 3H5CA 1SNGA 4AU4A 1DZHI 3F5NA 2BEHL 3ZHAA 1YXAA 1QLPA 2OAYA 2XN6A 3EVJI 5IO1A 5CE0A 4EB1I 1A7CA 1OYHI 1DB2A 2XN7A 1E05I 3DLWA 3NDAA 4GA7A 1OC0A 3DRMA 1SEKA 4P0FA 4G8OA 1XQGA 1SR5A 2BEHI 2OL2A 3Q02A 1JJOC 4AQHA 1C8OA 2PEEA 4PYWA 1OVAA 2WXYC 3EOXA 1DZGL 1ATTA 4ZK0A 2VH4A 4X30A 2WXZC 3CAAA 2V95A 3FGQA
chains in the Genus database with same CATH superfamily
1ATHA 1WZ9A 4Y40A 2B4XL 2HIJL 2ARQA 5HGCA 4DY0A 2ARRA 2B5TI 4BB2A 4AU3B 3VVJA 3KCGI 1IMVA 2VDYA 1LQ8A 3CVMA 4IC0A 4ZK3A 1DZGI 5CDZA 8APIA 3T1PA 1JMOA 1DVNA 1OO8A 2XN3A 1ATUA 1JRRA 1MTPA 1UHGA 2VDXA 2HIJI 4KDSA 5BRRI 4Y3KA 1JTIA 1T1FA 1DVMA 2ZNHA 1BR8I 2H4RA 1F0CA 1NQ9I 1XQJA 3B9FI 2ZV6A 4ROAA 4RSQA 1OPHA 1QMBA 1B3KA 1TB6I 1HP7A 3Q03A 1LK6I 4C49A 1C5GA 3F02A 2WXWA 3NE4A 2HI9A 2ACHA 1E03I 1JMJA 2WY0C 1XU8A 4AJTA 2D26A 1D5SA 1QMNA 3NDDA 7APIA 2WXXA 3NDFA 2B4XI 1AZXI 2XN5A 9APIA 4AFXA 1BY7A 2PEFA 2WY1A 2H4PA 2H4QA 2QUGA 2GD4C 1AS4A 3F1SA 2RIWA 2CEOA 4DY7C 3CWLA 9PAIA 4G8RA 1OVAB 1OVAC 1KCTA 3LE2A 2RIVA 3R4LA 4AU3A 3UT3A 4CAAA 2R9YA 1M93B 4AJUA 3STOA 1JVQI 5C98A 3DRUA 4IF8A 4ROBA 1IZ2A 5CDXA 1EZXA 4R9IA 3PB1I 4DTEA 1PSIA 4AU2A 1ANTI 1DZHL 1R1LI 2DUTA 3DY0A 3OZQA 5INWA 1HLEA 4P0OA 2ANTI 4YIAA 3LW2A 5EI0A 1E04I 2WXZA 4RO9A 4EB1L 1LJ5A 1OYHL 1K9OI 3PZFA 4C41A 3CWMA 3H5CA 1SNGA 4AU4A 1DZHI 3F5NA 2BEHL 3ZHAA 1YXAA 1QLPA 2OAYA 2XN6A 3EVJI 5IO1A 5CE0A 4EB1I 1A7CA 1OYHI 1DB2A 2XN7A 1E05I 3DLWA 3NDAA 4GA7A 1OC0A 3DRMA 1SEKA 4P0FA 4G8OA 1XQGA 1SR5A 2BEHI 2OL2A 3Q02A 1JJOC 4AQHA 1C8OA 2PEEA 4PYWA 1OVAA 2WXYC 3EOXA 1DZGL 1ATTA 4ZK0A 2VH4A 4X30A 2WXZC 3CAAA 2V95A 3FGQA
chains in the Genus database with same CATH topology
1ATHA 1WZ9A 4Y40A 2B4XL 2HIJL 2ARQA 5HGCA 4DY0A 2ARRA 2B5TI 4BB2A 4AU3B 3VVJA 3KCGI 1IMVA 2VDYA 1LQ8A 3CVMA 4IC0A 4ZK3A 1DZGI 5CDZA 8APIA 3T1PA 1JMOA 1DVNA 1OO8A 2XN3A 1ATUA 1JRRA 1MTPA 1UHGA 2VDXA 2HIJI 4KDSA 5BRRI 4Y3KA 1JTIA 1T1FA 1DVMA 2ZNHA 1BR8I 2H4RA 1F0CA 1NQ9I 1XQJA 3B9FI 2ZV6A 4ROAA 4RSQA 1OPHA 1QMBA 1B3KA 1TB6I 1HP7A 3Q03A 1LK6I 4C49A 1C5GA 3F02A 2WXWA 3NE4A 2HI9A 2ACHA 1E03I 1JMJA 2WY0C 1XU8A 4AJTA 2D26A 1D5SA 1QMNA 3NDDA 7APIA 2WXXA 3NDFA 2B4XI 1AZXI 2XN5A 9APIA 4AFXA 1BY7A 2PEFA 2WY1A 2H4PA 2H4QA 2QUGA 2GD4C 1AS4A 3F1SA 2RIWA 2CEOA 4DY7C 3CWLA 9PAIA 4G8RA 1OVAB 1OVAC 1KCTA 3LE2A 2RIVA 3R4LA 4AU3A 3UT3A 4CAAA 2R9YA 1M93B 4AJUA 3STOA 1JVQI 5C98A 3DRUA 4IF8A 4ROBA 1IZ2A 5CDXA 1EZXA 4R9IA 3PB1I 4DTEA 1PSIA 4AU2A 1ANTI 1DZHL 1R1LI 2DUTA 3DY0A 3OZQA 5INWA 1HLEA 4P0OA 2ANTI 4YIAA 3LW2A 5EI0A 1E04I 2WXZA 4RO9A 4EB1L 1LJ5A 1OYHL 1K9OI 3PZFA 4C41A 3CWMA 3H5CA 1SNGA 4AU4A 1DZHI 3F5NA 2BEHL 3ZHAA 1YXAA 1QLPA 2OAYA 2XN6A 3EVJI 5IO1A 5CE0A 4EB1I 1A7CA 1OYHI 1DB2A 2XN7A 1E05I 3DLWA 3NDAA 4GA7A 1OC0A 3DRMA 1SEKA 4P0FA 4G8OA 1XQGA 1SR5A 2BEHI 2OL2A 3Q02A 1JJOC 4AQHA 1C8OA 2PEEA 4PYWA 1OVAA 2WXYC 3EOXA 1DZGL 1ATTA 4ZK0A 2VH4A 4X30A 2WXZC 3CAAA 2V95A 3FGQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ATH A;  1WZ9 A;  4Y40 A;  2B4X L;  2HIJ L;  2ARQ A;  5HGC A;  4DY0 A;  2ARR A;  2B5T I;  4BB2 A;  4AU3 B;  3VVJ A;  3KCG I;  1IMV A;  2VDY A;  1LQ8 A;  3CVM A;  4IC0 A;  4ZK3 A;  1DZG I;  5CDZ A;  8API A;  3T1P A;  1JMO A;  1DVN A;  1OO8 A;  2XN3 A;  1ATU A;  1JRR A;  1MTP A;  1UHG A;  2VDX A;  2HIJ I;  4KDS A;  5BRR I;  4Y3K A;  1JTI A;  1T1F A;  1DVM A;  2ZNH A;  1BR8 I;  2H4R A;  1F0C A;  1NQ9 I;  1XQJ A;  3B9F I;  2ZV6 A;  4ROA A;  4RSQ A;  1OPH A;  1QMB A;  1B3K A;  1TB6 I;  1HP7 A;  3Q03 A;  1LK6 I;  4C49 A;  1C5G A;  3F02 A;  2WXW A;  3NE4 A;  2HI9 A;  2ACH A;  1E03 I;  1JMJ A;  2WY0 C;  1XU8 A;  4AJT A;  2D26 A;  1D5S A;  1QMN A;  3NDD A;  7API A;  2WXX A;  3NDF A;  2B4X I;  1AZX I;  2XN5 A;  9API A;  4AFX A;  1BY7 A;  2PEF A;  2WY1 A;  2H4P A;  2H4Q A;  2QUG A;  2GD4 C;  1AS4 A;  3F1S A;  2RIW A;  2CEO A;  4DY7 C;  3CWL A;  9PAI A;  4G8R A;  1OVA B;  1OVA C;  1KCT A;  3LE2 A;  2RIV A;  3R4L A;  4AU3 A;  3UT3 A;  4CAA A;  2R9Y A;  1M93 B;  4AJU A;  3STO A;  1JVQ I;  5C98 A;  3DRU A;  4IF8 A;  4ROB A;  1IZ2 A;  5CDX A;  1EZX A;  4R9I A;  3PB1 I;  4DTE A;  1PSI A;  4AU2 A;  1ANT I;  1DZH L;  1R1L I;  2DUT A;  3DY0 A;  3OZQ A;  5INW A;  1HLE A;  4P0O A;  2ANT I;  4YIA A;  3LW2 A;  5EI0 A;  1E04 I;  2WXZ A;  4RO9 A;  4EB1 L;  1LJ5 A;  1OYH L;  1K9O I;  3PZF A;  4C41 A;  3CWM A;  3H5C A;  1SNG A;  4AU4 A;  1DZH I;  3F5N A;  2BEH L;  3ZHA A;  1YXA A;  1QLP A;  2OAY A;  2XN6 A;  3EVJ I;  5IO1 A;  5CE0 A;  4EB1 I;  1A7C A;  1OYH I;  1DB2 A;  2XN7 A;  1E05 I;  3DLW A;  3NDA A;  4GA7 A;  1OC0 A;  3DRM A;  1SEK A;  4P0F A;  4G8O A;  1XQG A;  1SR5 A;  2BEH I;  2OL2 A;  3Q02 A;  1JJO C;  4AQH A;  1C8O A;  2PEE A;  4PYW A;  1OVA A;  2WXY C;  3EOX A;  1DZG L;  1ATT A;  4ZK0 A;  2VH4 A;  4X30 A;  2WXZ C;  3CAA A;  2V95 A;  3FGQ A; 
#chains in the Genus database with same CATH topology
 1ATH A;  1WZ9 A;  4Y40 A;  2B4X L;  2HIJ L;  2ARQ A;  5HGC A;  4DY0 A;  2ARR A;  2B5T I;  4BB2 A;  4AU3 B;  3VVJ A;  3KCG I;  1IMV A;  2VDY A;  1LQ8 A;  3CVM A;  4IC0 A;  4ZK3 A;  1DZG I;  5CDZ A;  8API A;  3T1P A;  1JMO A;  1DVN A;  1OO8 A;  2XN3 A;  1ATU A;  1JRR A;  1MTP A;  1UHG A;  2VDX A;  2HIJ I;  4KDS A;  5BRR I;  4Y3K A;  1JTI A;  1T1F A;  1DVM A;  2ZNH A;  1BR8 I;  2H4R A;  1F0C A;  1NQ9 I;  1XQJ A;  3B9F I;  2ZV6 A;  4ROA A;  4RSQ A;  1OPH A;  1QMB A;  1B3K A;  1TB6 I;  1HP7 A;  3Q03 A;  1LK6 I;  4C49 A;  1C5G A;  3F02 A;  2WXW A;  3NE4 A;  2HI9 A;  2ACH A;  1E03 I;  1JMJ A;  2WY0 C;  1XU8 A;  4AJT A;  2D26 A;  1D5S A;  1QMN A;  3NDD A;  7API A;  2WXX A;  3NDF A;  2B4X I;  1AZX I;  2XN5 A;  9API A;  4AFX A;  1BY7 A;  2PEF A;  2WY1 A;  2H4P A;  2H4Q A;  2QUG A;  2GD4 C;  1AS4 A;  3F1S A;  2RIW A;  2CEO A;  4DY7 C;  3CWL A;  9PAI A;  4G8R A;  1OVA B;  1OVA C;  1KCT A;  3LE2 A;  2RIV A;  3R4L A;  4AU3 A;  3UT3 A;  4CAA A;  2R9Y A;  1M93 B;  4AJU A;  3STO A;  1JVQ I;  5C98 A;  3DRU A;  4IF8 A;  4ROB A;  1IZ2 A;  5CDX A;  1EZX A;  4R9I A;  3PB1 I;  4DTE A;  1PSI A;  4AU2 A;  1ANT I;  1DZH L;  1R1L I;  2DUT A;  3DY0 A;  3OZQ A;  5INW A;  1HLE A;  4P0O A;  2ANT I;  4YIA A;  3LW2 A;  5EI0 A;  1E04 I;  2WXZ A;  4RO9 A;  4EB1 L;  1LJ5 A;  1OYH L;  1K9O I;  3PZF A;  4C41 A;  3CWM A;  3H5C A;  1SNG A;  4AU4 A;  1DZH I;  3F5N A;  2BEH L;  3ZHA A;  1YXA A;  1QLP A;  2OAY A;  2XN6 A;  3EVJ I;  5IO1 A;  5CE0 A;  4EB1 I;  1A7C A;  1OYH I;  1DB2 A;  2XN7 A;  1E05 I;  3DLW A;  3NDA A;  4GA7 A;  1OC0 A;  3DRM A;  1SEK A;  4P0F A;  4G8O A;  1XQG A;  1SR5 A;  2BEH I;  2OL2 A;  3Q02 A;  1JJO C;  4AQH A;  1C8O A;  2PEE A;  4PYW A;  1OVA A;  2WXY C;  3EOX A;  1DZG L;  1ATT A;  4ZK0 A;  2VH4 A;  4X30 A;  2WXZ C;  3CAA A;  2V95 A;  3FGQ A; 
#chains in the Genus database with same CATH homology
 1ATH A;  1WZ9 A;  4Y40 A;  2B4X L;  2HIJ L;  2ARQ A;  5HGC A;  4DY0 A;  2ARR A;  2B5T I;  4BB2 A;  4AU3 B;  3VVJ A;  3KCG I;  1IMV A;  2VDY A;  1LQ8 A;  3CVM A;  4IC0 A;  4ZK3 A;  1DZG I;  5CDZ A;  8API A;  3T1P A;  1JMO A;  1DVN A;  1OO8 A;  2XN3 A;  1ATU A;  1JRR A;  1MTP A;  1UHG A;  2VDX A;  2HIJ I;  4KDS A;  5BRR I;  4Y3K A;  1JTI A;  1T1F A;  1DVM A;  2ZNH A;  1BR8 I;  2H4R A;  1F0C A;  1NQ9 I;  1XQJ A;  3B9F I;  2ZV6 A;  4ROA A;  4RSQ A;  1OPH A;  1QMB A;  1B3K A;  1TB6 I;  1HP7 A;  3Q03 A;  1LK6 I;  4C49 A;  1C5G A;  3F02 A;  2WXW A;  3NE4 A;  2HI9 A;  2ACH A;  1E03 I;  1JMJ A;  2WY0 C;  1XU8 A;  4AJT A;  2D26 A;  1D5S A;  1QMN A;  3NDD A;  7API A;  2WXX A;  3NDF A;  2B4X I;  1AZX I;  2XN5 A;  9API A;  4AFX A;  1BY7 A;  2PEF A;  2WY1 A;  2H4P A;  2H4Q A;  2QUG A;  2GD4 C;  1AS4 A;  3F1S A;  2RIW A;  2CEO A;  4DY7 C;  3CWL A;  9PAI A;  4G8R A;  1OVA B;  1OVA C;  1KCT A;  3LE2 A;  2RIV A;  3R4L A;  4AU3 A;  3UT3 A;  4CAA A;  2R9Y A;  1M93 B;  4AJU A;  3STO A;  1JVQ I;  5C98 A;  3DRU A;  4IF8 A;  4ROB A;  1IZ2 A;  5CDX A;  1EZX A;  4R9I A;  3PB1 I;  4DTE A;  1PSI A;  4AU2 A;  1ANT I;  1DZH L;  1R1L I;  2DUT A;  3DY0 A;  3OZQ A;  5INW A;  1HLE A;  4P0O A;  2ANT I;  4YIA A;  3LW2 A;  5EI0 A;  1E04 I;  2WXZ A;  4RO9 A;  4EB1 L;  1LJ5 A;  1OYH L;  1K9O I;  3PZF A;  4C41 A;  3CWM A;  3H5C A;  1SNG A;  4AU4 A;  1DZH I;  3F5N A;  2BEH L;  3ZHA A;  1YXA A;  1QLP A;  2OAY A;  2XN6 A;  3EVJ I;  5IO1 A;  5CE0 A;  4EB1 I;  1A7C A;  1OYH I;  1DB2 A;  2XN7 A;  1E05 I;  3DLW A;  3NDA A;  4GA7 A;  1OC0 A;  3DRM A;  1SEK A;  4P0F A;  4G8O A;  1XQG A;  1SR5 A;  2BEH I;  2OL2 A;  3Q02 A;  1JJO C;  4AQH A;  1C8O A;  2PEE A;  4PYW A;  1OVA A;  2WXY C;  3EOX A;  1DZG L;  1ATT A;  4ZK0 A;  2VH4 A;  4X30 A;  2WXZ C;  3CAA A;  2V95 A;  3FGQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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