2WXZC

Crystal structure of rat angiotensinogen in c2 space group
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
Knots found
sequence length
445
structure length
413
Chain Sequence
HPFHLLYYSKSTCAQTLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
molecule keywords ANGIOTENSINOGEN
publication title A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
pubmed doi rcsb
source organism Rattus norvegicus
total genus 106
structure length 413
sequence length 445
other databases KnotProt 2.0: S +31
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2wxzC01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2wxzC02
3R4LA 2XN3A 2ZNHA 3PB1I 3H5CA 1JTIA 1LK6I 1R1LI 1IMVA 4AU3A 4DY7C 2WY1A 4PYWA 1A7CA 5BRRI 4RO9A 4P0OA 2B4XI 1M93B 4EB1I 2OAYA 2ARQA 1DVNA 3DLWA 1BR8I 2WXYC 1OYHI 2XN6A 2HI9A 3T1PA 1NQ9I 1OPHA 9PAIA 4C41A 1LQ8A 3CWMA 3PZFA 1AZXI 4KDSA 1HLEA 3VVJA 1SEKA 2VH4A 3NDAA 4Y3KA 1IZ2A 2HIJL 3FGQA 2WXXA 5C98A 5HGCA 4BB2A 2GD4C 4ROAA 4C49A 3F02A 1DB2A 2XN7A 2ACHA 3EOXA 1XU8A 3CWLA 2WY0C 2PEEA 1BY7A 4ZK0A 1C5GA 1DZHI 4G8OA 4ROBA 2ZV6A 1XQGA 1TB6I 4YIAA 2BEHI 1WZ9A 1K9OI 2PEFA 2CEOA 2ARRA 1KCTA 2WXZA 1DZGL 2R9YA 3F1SA 4X30A 2WXWA 5INWA 3ZHAA 1XQJA 3KCGI 3DRUA 4AJTA 2QUGA 4CAAA 4DY0A 2WXZC 1JVQI 4IC0A 4GA7A 4AQHA 3NDDA 1PSIA 1ANTI 3B9FI 7APIA 5CE0A 3LE2A 1LJ5A 1QMNA 2V95A 3STOA 2ANTI 1YXAA 3EVJI 1JRRA 4AU2A 1MTPA 2VDYA 1C8OA 2B4XL 1SR5A 1OVAA 4AU3B 4EB1L 4AFXA 1JJOC 1OVAC 3NE4A 3F5NA 3CAAA 3DRMA 1ATHA 1OC0A 1UHGA 4AU4A 2HIJI 1F0CA 5CDXA 2D26A 3Q02A 1B3KA 2B5TI 1SNGA 1AS4A 1HP7A 1JMOA 3OZQA 4R9IA 5CDZA 1E04I 2H4QA 4G8RA 1JMJA 2XN5A 2H4RA 3LW2A 2RIVA 1DVMA 1D5SA 4RSQA 3Q03A 3NDFA 1E05I 4DTEA 4AJUA 4ZK3A 4IF8A 9APIA 3UT3A 5IO1A 1EZXA 3CVMA 3DY0A 2VDXA 1DZHL 1DZGI 1E03I 1OO8A 4P0FA 8APIA 4Y40A 1OYHL 1T1FA 2H4PA 2OL2A 1QLPA 1ATTA 2BEHL 2RIWA 1ATUA 2DUTA 1OVAB 5EI0A 1QMBA
chains in the Genus database with same CATH superfamily
3R4LA 2XN3A 2ZNHA 3PB1I 3H5CA 1JTIA 1LK6I 1R1LI 1IMVA 4AU3A 4DY7C 2WY1A 4PYWA 1A7CA 5BRRI 4RO9A 4P0OA 2B4XI 1M93B 4EB1I 2OAYA 2ARQA 1DVNA 3DLWA 1BR8I 2WXYC 1OYHI 2XN6A 2HI9A 3T1PA 1NQ9I 1OPHA 9PAIA 4C41A 1LQ8A 3CWMA 3PZFA 1AZXI 4KDSA 1HLEA 3VVJA 1SEKA 2VH4A 3NDAA 4Y3KA 1IZ2A 2HIJL 3FGQA 2WXXA 5C98A 5HGCA 4BB2A 2GD4C 4ROAA 4C49A 3F02A 1DB2A 2XN7A 2ACHA 3EOXA 1XU8A 3CWLA 2WY0C 2PEEA 1BY7A 4ZK0A 1C5GA 1DZHI 4G8OA 4ROBA 2ZV6A 1XQGA 1TB6I 4YIAA 2BEHI 1WZ9A 1K9OI 2PEFA 2CEOA 2ARRA 1KCTA 2WXZA 1DZGL 2R9YA 3F1SA 4X30A 2WXWA 5INWA 3ZHAA 1XQJA 3KCGI 3DRUA 4AJTA 2QUGA 4CAAA 4DY0A 2WXZC 1JVQI 4IC0A 4GA7A 4AQHA 3NDDA 1PSIA 1ANTI 3B9FI 7APIA 5CE0A 3LE2A 1LJ5A 1QMNA 2V95A 3STOA 2ANTI 1YXAA 3EVJI 1JRRA 4AU2A 1MTPA 2VDYA 1C8OA 2B4XL 1SR5A 1OVAA 4AU3B 4EB1L 4AFXA 1JJOC 1OVAC 3NE4A 3F5NA 3CAAA 3DRMA 1ATHA 1OC0A 1UHGA 4AU4A 2HIJI 1F0CA 5CDXA 2D26A 3Q02A 1B3KA 2B5TI 1SNGA 1AS4A 1HP7A 1JMOA 3OZQA 4R9IA 5CDZA 1E04I 2H4QA 4G8RA 1JMJA 2XN5A 2H4RA 3LW2A 2RIVA 1DVMA 1D5SA 4RSQA 3Q03A 3NDFA 1E05I 4DTEA 4AJUA 4ZK3A 4IF8A 9APIA 3UT3A 5IO1A 1EZXA 3CVMA 3DY0A 2VDXA 1DZHL 1DZGI 1E03I 1OO8A 4P0FA 8APIA 4Y40A 1OYHL 1T1FA 2H4PA 2OL2A 1QLPA 1ATTA 2BEHL 2RIWA 1ATUA 2DUTA 1OVAB 5EI0A 1QMBA
chains in the Genus database with same CATH topology
3R4LA 2XN3A 2ZNHA 3PB1I 3H5CA 1JTIA 1LK6I 1R1LI 1IMVA 4AU3A 4DY7C 2WY1A 4PYWA 1A7CA 5BRRI 4RO9A 4P0OA 2B4XI 1M93B 4EB1I 2OAYA 2ARQA 1DVNA 3DLWA 1BR8I 2WXYC 1OYHI 2XN6A 2HI9A 3T1PA 1NQ9I 1OPHA 9PAIA 4C41A 1LQ8A 3CWMA 3PZFA 1AZXI 4KDSA 1HLEA 3VVJA 1SEKA 2VH4A 3NDAA 4Y3KA 1IZ2A 2HIJL 3FGQA 2WXXA 5C98A 5HGCA 4BB2A 2GD4C 4ROAA 4C49A 3F02A 1DB2A 2XN7A 2ACHA 3EOXA 1XU8A 3CWLA 2WY0C 2PEEA 1BY7A 4ZK0A 1C5GA 1DZHI 4G8OA 4ROBA 2ZV6A 1XQGA 1TB6I 4YIAA 2BEHI 1WZ9A 1K9OI 2PEFA 2CEOA 2ARRA 1KCTA 2WXZA 1DZGL 2R9YA 3F1SA 4X30A 2WXWA 5INWA 3ZHAA 1XQJA 3KCGI 3DRUA 4AJTA 2QUGA 4CAAA 4DY0A 2WXZC 1JVQI 4IC0A 4GA7A 4AQHA 3NDDA 1PSIA 1ANTI 3B9FI 7APIA 5CE0A 3LE2A 1LJ5A 1QMNA 2V95A 3STOA 2ANTI 1YXAA 3EVJI 1JRRA 4AU2A 1MTPA 2VDYA 1C8OA 2B4XL 1SR5A 1OVAA 4AU3B 4EB1L 4AFXA 1JJOC 1OVAC 3NE4A 3F5NA 3CAAA 3DRMA 1ATHA 1OC0A 1UHGA 4AU4A 2HIJI 1F0CA 5CDXA 2D26A 3Q02A 1B3KA 2B5TI 1SNGA 1AS4A 1HP7A 1JMOA 3OZQA 4R9IA 5CDZA 1E04I 2H4QA 4G8RA 1JMJA 2XN5A 2H4RA 3LW2A 2RIVA 1DVMA 1D5SA 4RSQA 3Q03A 3NDFA 1E05I 4DTEA 4AJUA 4ZK3A 4IF8A 9APIA 3UT3A 5IO1A 1EZXA 3CVMA 3DY0A 2VDXA 1DZHL 1DZGI 1E03I 1OO8A 4P0FA 8APIA 4Y40A 1OYHL 1T1FA 2H4PA 2OL2A 1QLPA 1ATTA 2BEHL 2RIWA 1ATUA 2DUTA 1OVAB 5EI0A 1QMBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R4L A;  2XN3 A;  2ZNH A;  3PB1 I;  3H5C A;  1JTI A;  1LK6 I;  1R1L I;  1IMV A;  4AU3 A;  4DY7 C;  2WY1 A;  4PYW A;  1A7C A;  5BRR I;  4RO9 A;  4P0O A;  2B4X I;  1M93 B;  4EB1 I;  2OAY A;  2ARQ A;  1DVN A;  3DLW A;  1BR8 I;  2WXY C;  1OYH I;  2XN6 A;  2HI9 A;  3T1P A;  1NQ9 I;  1OPH A;  9PAI A;  4C41 A;  1LQ8 A;  3CWM A;  3PZF A;  1AZX I;  4KDS A;  1HLE A;  3VVJ A;  1SEK A;  2VH4 A;  3NDA A;  4Y3K A;  1IZ2 A;  2HIJ L;  3FGQ A;  2WXX A;  5C98 A;  5HGC A;  4BB2 A;  2GD4 C;  4ROA A;  4C49 A;  3F02 A;  1DB2 A;  2XN7 A;  2ACH A;  3EOX A;  1XU8 A;  3CWL A;  2WY0 C;  2PEE A;  1BY7 A;  4ZK0 A;  1C5G A;  1DZH I;  4G8O A;  4ROB A;  2ZV6 A;  1XQG A;  1TB6 I;  4YIA A;  2BEH I;  1WZ9 A;  1K9O I;  2PEF A;  2CEO A;  2ARR A;  1KCT A;  2WXZ A;  1DZG L;  2R9Y A;  3F1S A;  4X30 A;  2WXW A;  5INW A;  3ZHA A;  1XQJ A;  3KCG I;  3DRU A;  4AJT A;  2QUG A;  4CAA A;  4DY0 A;  2WXZ C;  1JVQ I;  4IC0 A;  4GA7 A;  4AQH A;  3NDD A;  1PSI A;  1ANT I;  3B9F I;  7API A;  5CE0 A;  3LE2 A;  1LJ5 A;  1QMN A;  2V95 A;  3STO A;  2ANT I;  1YXA A;  3EVJ I;  1JRR A;  4AU2 A;  1MTP A;  2VDY A;  1C8O A;  2B4X L;  1SR5 A;  1OVA A;  4AU3 B;  4EB1 L;  4AFX A;  1JJO C;  1OVA C;  3NE4 A;  3F5N A;  3CAA A;  3DRM A;  1ATH A;  1OC0 A;  1UHG A;  4AU4 A;  2HIJ I;  1F0C A;  5CDX A;  2D26 A;  3Q02 A;  1B3K A;  2B5T I;  1SNG A;  1AS4 A;  1HP7 A;  1JMO A;  3OZQ A;  4R9I A;  5CDZ A;  1E04 I;  2H4Q A;  4G8R A;  1JMJ A;  2XN5 A;  2H4R A;  3LW2 A;  2RIV A;  1DVM A;  1D5S A;  4RSQ A;  3Q03 A;  3NDF A;  1E05 I;  4DTE A;  4AJU A;  4ZK3 A;  4IF8 A;  9API A;  3UT3 A;  5IO1 A;  1EZX A;  3CVM A;  3DY0 A;  2VDX A;  1DZH L;  1DZG I;  1E03 I;  1OO8 A;  4P0F A;  8API A;  4Y40 A;  1OYH L;  1T1F A;  2H4P A;  2OL2 A;  1QLP A;  1ATT A;  2BEH L;  2RIW A;  1ATU A;  2DUT A;  1OVA B;  5EI0 A;  1QMB A; 
#chains in the Genus database with same CATH topology
 3R4L A;  2XN3 A;  2ZNH A;  3PB1 I;  3H5C A;  1JTI A;  1LK6 I;  1R1L I;  1IMV A;  4AU3 A;  4DY7 C;  2WY1 A;  4PYW A;  1A7C A;  5BRR I;  4RO9 A;  4P0O A;  2B4X I;  1M93 B;  4EB1 I;  2OAY A;  2ARQ A;  1DVN A;  3DLW A;  1BR8 I;  2WXY C;  1OYH I;  2XN6 A;  2HI9 A;  3T1P A;  1NQ9 I;  1OPH A;  9PAI A;  4C41 A;  1LQ8 A;  3CWM A;  3PZF A;  1AZX I;  4KDS A;  1HLE A;  3VVJ A;  1SEK A;  2VH4 A;  3NDA A;  4Y3K A;  1IZ2 A;  2HIJ L;  3FGQ A;  2WXX A;  5C98 A;  5HGC A;  4BB2 A;  2GD4 C;  4ROA A;  4C49 A;  3F02 A;  1DB2 A;  2XN7 A;  2ACH A;  3EOX A;  1XU8 A;  3CWL A;  2WY0 C;  2PEE A;  1BY7 A;  4ZK0 A;  1C5G A;  1DZH I;  4G8O A;  4ROB A;  2ZV6 A;  1XQG A;  1TB6 I;  4YIA A;  2BEH I;  1WZ9 A;  1K9O I;  2PEF A;  2CEO A;  2ARR A;  1KCT A;  2WXZ A;  1DZG L;  2R9Y A;  3F1S A;  4X30 A;  2WXW A;  5INW A;  3ZHA A;  1XQJ A;  3KCG I;  3DRU A;  4AJT A;  2QUG A;  4CAA A;  4DY0 A;  2WXZ C;  1JVQ I;  4IC0 A;  4GA7 A;  4AQH A;  3NDD A;  1PSI A;  1ANT I;  3B9F I;  7API A;  5CE0 A;  3LE2 A;  1LJ5 A;  1QMN A;  2V95 A;  3STO A;  2ANT I;  1YXA A;  3EVJ I;  1JRR A;  4AU2 A;  1MTP A;  2VDY A;  1C8O A;  2B4X L;  1SR5 A;  1OVA A;  4AU3 B;  4EB1 L;  4AFX A;  1JJO C;  1OVA C;  3NE4 A;  3F5N A;  3CAA A;  3DRM A;  1ATH A;  1OC0 A;  1UHG A;  4AU4 A;  2HIJ I;  1F0C A;  5CDX A;  2D26 A;  3Q02 A;  1B3K A;  2B5T I;  1SNG A;  1AS4 A;  1HP7 A;  1JMO A;  3OZQ A;  4R9I A;  5CDZ A;  1E04 I;  2H4Q A;  4G8R A;  1JMJ A;  2XN5 A;  2H4R A;  3LW2 A;  2RIV A;  1DVM A;  1D5S A;  4RSQ A;  3Q03 A;  3NDF A;  1E05 I;  4DTE A;  4AJU A;  4ZK3 A;  4IF8 A;  9API A;  3UT3 A;  5IO1 A;  1EZX A;  3CVM A;  3DY0 A;  2VDX A;  1DZH L;  1DZG I;  1E03 I;  1OO8 A;  4P0F A;  8API A;  4Y40 A;  1OYH L;  1T1F A;  2H4P A;  2OL2 A;  1QLP A;  1ATT A;  2BEH L;  2RIW A;  1ATU A;  2DUT A;  1OVA B;  5EI0 A;  1QMB A; 
#chains in the Genus database with same CATH homology
 3R4L A;  2XN3 A;  2ZNH A;  3PB1 I;  3H5C A;  1JTI A;  1LK6 I;  1R1L I;  1IMV A;  4AU3 A;  4DY7 C;  2WY1 A;  4PYW A;  1A7C A;  5BRR I;  4RO9 A;  4P0O A;  2B4X I;  1M93 B;  4EB1 I;  2OAY A;  2ARQ A;  1DVN A;  3DLW A;  1BR8 I;  2WXY C;  1OYH I;  2XN6 A;  2HI9 A;  3T1P A;  1NQ9 I;  1OPH A;  9PAI A;  4C41 A;  1LQ8 A;  3CWM A;  3PZF A;  1AZX I;  4KDS A;  1HLE A;  3VVJ A;  1SEK A;  2VH4 A;  3NDA A;  4Y3K A;  1IZ2 A;  2HIJ L;  3FGQ A;  2WXX A;  5C98 A;  5HGC A;  4BB2 A;  2GD4 C;  4ROA A;  4C49 A;  3F02 A;  1DB2 A;  2XN7 A;  2ACH A;  3EOX A;  1XU8 A;  3CWL A;  2WY0 C;  2PEE A;  1BY7 A;  4ZK0 A;  1C5G A;  1DZH I;  4G8O A;  4ROB A;  2ZV6 A;  1XQG A;  1TB6 I;  4YIA A;  2BEH I;  1WZ9 A;  1K9O I;  2PEF A;  2CEO A;  2ARR A;  1KCT A;  2WXZ A;  1DZG L;  2R9Y A;  3F1S A;  4X30 A;  2WXW A;  5INW A;  3ZHA A;  1XQJ A;  3KCG I;  3DRU A;  4AJT A;  2QUG A;  4CAA A;  4DY0 A;  2WXZ C;  1JVQ I;  4IC0 A;  4GA7 A;  4AQH A;  3NDD A;  1PSI A;  1ANT I;  3B9F I;  7API A;  5CE0 A;  3LE2 A;  1LJ5 A;  1QMN A;  2V95 A;  3STO A;  2ANT I;  1YXA A;  3EVJ I;  1JRR A;  4AU2 A;  1MTP A;  2VDY A;  1C8O A;  2B4X L;  1SR5 A;  1OVA A;  4AU3 B;  4EB1 L;  4AFX A;  1JJO C;  1OVA C;  3NE4 A;  3F5N A;  3CAA A;  3DRM A;  1ATH A;  1OC0 A;  1UHG A;  4AU4 A;  2HIJ I;  1F0C A;  5CDX A;  2D26 A;  3Q02 A;  1B3K A;  2B5T I;  1SNG A;  1AS4 A;  1HP7 A;  1JMO A;  3OZQ A;  4R9I A;  5CDZ A;  1E04 I;  2H4Q A;  4G8R A;  1JMJ A;  2XN5 A;  2H4R A;  3LW2 A;  2RIV A;  1DVM A;  1D5S A;  4RSQ A;  3Q03 A;  3NDF A;  1E05 I;  4DTE A;  4AJU A;  4ZK3 A;  4IF8 A;  9API A;  3UT3 A;  5IO1 A;  1EZX A;  3CVM A;  3DY0 A;  2VDX A;  1DZH L;  1DZG I;  1E03 I;  1OO8 A;  4P0F A;  8API A;  4Y40 A;  1OYH L;  1T1F A;  2H4P A;  2OL2 A;  1QLP A;  1ATT A;  2BEH L;  2RIW A;  1ATU A;  2DUT A;  1OVA B;  5EI0 A;  1QMB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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