2WY0C

Crystal structure of mouse angiotensinogen in the oxidised form with space group p6122
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
450
structure length
424
Chain Sequence
DRVYIHPFHLLYHNKSTCETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTTPLLQSIVVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCISDLDRVEALIFQDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
pubmed doi rcsb
molecule tags Hormone
source organism Mus musculus
molecule keywords ANGIOTENSINOGEN
total genus 126
structure length 424
sequence length 450
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 2wy0C01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 2wy0C02
3B9FI 4AU3A 1K9OI 2RIWA 1UHGA 4AQHA 4AU2A 1JMJA 4ROAA 4IF8A 7APIA 1LQ8A 3ZHAA 1OVAA 4AU4A 5INWA 2WY0C 2ZV6A 1E04I 1DZHL 1T1FA 1PSIA 1DVMA 4EB1L 4X30A 3DLWA 1WZ9A 2QUGA 1XQJA 2ARRA 2OAYA 4ZK0A 3F02A 1DZHI 5C98A 4KDSA 4ROBA 3NE4A 2WXWA 3DRMA 4EB1I 1M93B 1DZGL 8APIA 3NDDA 2H4PA 2WXXA 3NDAA 3DY0A 1SR5A 2R9YA 1ANTI 1IMVA 4DTEA 1OC0A 1QMBA 3KCGI 2D26A 1BY7A 1DZGI 1OYHL 2WXZA 1ATUA 2ARQA 4ZK3A 3PZFA 1A7CA 1E05I 1NQ9I 2WY1A 1HLEA 2OL2A 5CDXA 1OPHA 2GD4C 1MTPA 1OYHI 3R4LA 1LJ5A 1YXAA 4P0OA 4AU3B 2XN7A 4YIAA 5EI0A 3H5CA 3NDFA 1HP7A 2DUTA 5HGCA 2HIJL 1DVNA 2H4RA 2HI9A 1BR8I 3EOXA 3F5NA 3CWLA 4R9IA 1F0CA 3VVJA 1C5GA 1LK6I 1JVQI 4BB2A 2XN5A 2V95A 1QMNA 2HIJI 4RSQA 1AZXI 3CWMA 1C8OA 1R1LI 4G8RA 2PEEA 1QLPA 1TB6I 3CAAA 4DY7C 1IZ2A 4IC0A 5CDZA 5CE0A 2VDYA 1XQGA 3PB1I 4GA7A 3DRUA 3LW2A 4PYWA 4Y40A 4AJTA 2ANTI 3STOA 4AFXA 2CEOA 2PEFA 4C49A 1D5SA 4CAAA 1OVAB 1SEKA 2ACHA 5BRRI 3LE2A 1DB2A 1E03I 1OVAC 2B4XL 2B5TI 4Y3KA 1AS4A 2VH4A 1JJOC 4DY0A 9APIA 2VDXA 4AJUA 2XN3A 1XU8A 1JMOA 1OO8A 2WXYC 1KCTA 2XN6A 4RO9A 9PAIA 2B4XI 3FGQA 3UT3A 2BEHL 1SNGA 4C41A 5IO1A 3CVMA 1JRRA 1ATHA 3Q02A 1ATTA 3EVJI 4P0FA 3F1SA 2H4QA 3Q03A 3OZQA 1JTIA 1B3KA 2BEHI 2RIVA 1EZXA 3T1PA 2ZNHA 4G8OA 2WXZC
chains in the Genus database with same CATH superfamily
3B9FI 4AU3A 1K9OI 2RIWA 1UHGA 4AQHA 4AU2A 1JMJA 4ROAA 4IF8A 7APIA 1LQ8A 3ZHAA 1OVAA 4AU4A 5INWA 2WY0C 2ZV6A 1E04I 1DZHL 1T1FA 1PSIA 1DVMA 4EB1L 4X30A 3DLWA 1WZ9A 2QUGA 1XQJA 2ARRA 2OAYA 4ZK0A 3F02A 1DZHI 5C98A 4KDSA 4ROBA 3NE4A 2WXWA 3DRMA 4EB1I 1M93B 1DZGL 8APIA 3NDDA 2H4PA 2WXXA 3NDAA 3DY0A 1SR5A 2R9YA 1ANTI 1IMVA 4DTEA 1OC0A 1QMBA 3KCGI 2D26A 1BY7A 1DZGI 1OYHL 2WXZA 1ATUA 2ARQA 4ZK3A 3PZFA 1A7CA 1E05I 1NQ9I 2WY1A 1HLEA 2OL2A 5CDXA 1OPHA 2GD4C 1MTPA 1OYHI 3R4LA 1LJ5A 1YXAA 4P0OA 4AU3B 2XN7A 4YIAA 5EI0A 3H5CA 3NDFA 1HP7A 2DUTA 5HGCA 2HIJL 1DVNA 2H4RA 2HI9A 1BR8I 3EOXA 3F5NA 3CWLA 4R9IA 1F0CA 3VVJA 1C5GA 1LK6I 1JVQI 4BB2A 2XN5A 2V95A 1QMNA 2HIJI 4RSQA 1AZXI 3CWMA 1C8OA 1R1LI 4G8RA 2PEEA 1QLPA 1TB6I 3CAAA 4DY7C 1IZ2A 4IC0A 5CDZA 5CE0A 2VDYA 1XQGA 3PB1I 4GA7A 3DRUA 3LW2A 4PYWA 4Y40A 4AJTA 2ANTI 3STOA 4AFXA 2CEOA 2PEFA 4C49A 1D5SA 4CAAA 1OVAB 1SEKA 2ACHA 5BRRI 3LE2A 1DB2A 1E03I 1OVAC 2B4XL 2B5TI 4Y3KA 1AS4A 2VH4A 1JJOC 4DY0A 9APIA 2VDXA 4AJUA 2XN3A 1XU8A 1JMOA 1OO8A 2WXYC 1KCTA 2XN6A 4RO9A 9PAIA 2B4XI 3FGQA 3UT3A 2BEHL 1SNGA 4C41A 5IO1A 3CVMA 1JRRA 1ATHA 3Q02A 1ATTA 3EVJI 4P0FA 3F1SA 2H4QA 3Q03A 3OZQA 1JTIA 1B3KA 2BEHI 2RIVA 1EZXA 3T1PA 2ZNHA 4G8OA 2WXZC
chains in the Genus database with same CATH topology
3B9FI 4AU3A 1K9OI 2RIWA 1UHGA 4AQHA 4AU2A 1JMJA 4ROAA 4IF8A 7APIA 1LQ8A 3ZHAA 1OVAA 4AU4A 5INWA 2WY0C 2ZV6A 1E04I 1DZHL 1T1FA 1PSIA 1DVMA 4EB1L 4X30A 3DLWA 1WZ9A 2QUGA 1XQJA 2ARRA 2OAYA 4ZK0A 3F02A 1DZHI 5C98A 4KDSA 4ROBA 3NE4A 2WXWA 3DRMA 4EB1I 1M93B 1DZGL 8APIA 3NDDA 2H4PA 2WXXA 3NDAA 3DY0A 1SR5A 2R9YA 1ANTI 1IMVA 4DTEA 1OC0A 1QMBA 3KCGI 2D26A 1BY7A 1DZGI 1OYHL 2WXZA 1ATUA 2ARQA 4ZK3A 3PZFA 1A7CA 1E05I 1NQ9I 2WY1A 1HLEA 2OL2A 5CDXA 1OPHA 2GD4C 1MTPA 1OYHI 3R4LA 1LJ5A 1YXAA 4P0OA 4AU3B 2XN7A 4YIAA 5EI0A 3H5CA 3NDFA 1HP7A 2DUTA 5HGCA 2HIJL 1DVNA 2H4RA 2HI9A 1BR8I 3EOXA 3F5NA 3CWLA 4R9IA 1F0CA 3VVJA 1C5GA 1LK6I 1JVQI 4BB2A 2XN5A 2V95A 1QMNA 2HIJI 4RSQA 1AZXI 3CWMA 1C8OA 1R1LI 4G8RA 2PEEA 1QLPA 1TB6I 3CAAA 4DY7C 1IZ2A 4IC0A 5CDZA 5CE0A 2VDYA 1XQGA 3PB1I 4GA7A 3DRUA 3LW2A 4PYWA 4Y40A 4AJTA 2ANTI 3STOA 4AFXA 2CEOA 2PEFA 4C49A 1D5SA 4CAAA 1OVAB 1SEKA 2ACHA 5BRRI 3LE2A 1DB2A 1E03I 1OVAC 2B4XL 2B5TI 4Y3KA 1AS4A 2VH4A 1JJOC 4DY0A 9APIA 2VDXA 4AJUA 2XN3A 1XU8A 1JMOA 1OO8A 2WXYC 1KCTA 2XN6A 4RO9A 9PAIA 2B4XI 3FGQA 3UT3A 2BEHL 1SNGA 4C41A 5IO1A 3CVMA 1JRRA 1ATHA 3Q02A 1ATTA 3EVJI 4P0FA 3F1SA 2H4QA 3Q03A 3OZQA 1JTIA 1B3KA 2BEHI 2RIVA 1EZXA 3T1PA 2ZNHA 4G8OA 2WXZC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B9F I;  4AU3 A;  1K9O I;  2RIW A;  1UHG A;  4AQH A;  4AU2 A;  1JMJ A;  4ROA A;  4IF8 A;  7API A;  1LQ8 A;  3ZHA A;  1OVA A;  4AU4 A;  5INW A;  2WY0 C;  2ZV6 A;  1E04 I;  1DZH L;  1T1F A;  1PSI A;  1DVM A;  4EB1 L;  4X30 A;  3DLW A;  1WZ9 A;  2QUG A;  1XQJ A;  2ARR A;  2OAY A;  4ZK0 A;  3F02 A;  1DZH I;  5C98 A;  4KDS A;  4ROB A;  3NE4 A;  2WXW A;  3DRM A;  4EB1 I;  1M93 B;  1DZG L;  8API A;  3NDD A;  2H4P A;  2WXX A;  3NDA A;  3DY0 A;  1SR5 A;  2R9Y A;  1ANT I;  1IMV A;  4DTE A;  1OC0 A;  1QMB A;  3KCG I;  2D26 A;  1BY7 A;  1DZG I;  1OYH L;  2WXZ A;  1ATU A;  2ARQ A;  4ZK3 A;  3PZF A;  1A7C A;  1E05 I;  1NQ9 I;  2WY1 A;  1HLE A;  2OL2 A;  5CDX A;  1OPH A;  2GD4 C;  1MTP A;  1OYH I;  3R4L A;  1LJ5 A;  1YXA A;  4P0O A;  4AU3 B;  2XN7 A;  4YIA A;  5EI0 A;  3H5C A;  3NDF A;  1HP7 A;  2DUT A;  5HGC A;  2HIJ L;  1DVN A;  2H4R A;  2HI9 A;  1BR8 I;  3EOX A;  3F5N A;  3CWL A;  4R9I A;  1F0C A;  3VVJ A;  1C5G A;  1LK6 I;  1JVQ I;  4BB2 A;  2XN5 A;  2V95 A;  1QMN A;  2HIJ I;  4RSQ A;  1AZX I;  3CWM A;  1C8O A;  1R1L I;  4G8R A;  2PEE A;  1QLP A;  1TB6 I;  3CAA A;  4DY7 C;  1IZ2 A;  4IC0 A;  5CDZ A;  5CE0 A;  2VDY A;  1XQG A;  3PB1 I;  4GA7 A;  3DRU A;  3LW2 A;  4PYW A;  4Y40 A;  4AJT A;  2ANT I;  3STO A;  4AFX A;  2CEO A;  2PEF A;  4C49 A;  1D5S A;  4CAA A;  1OVA B;  1SEK A;  2ACH A;  5BRR I;  3LE2 A;  1DB2 A;  1E03 I;  1OVA C;  2B4X L;  2B5T I;  4Y3K A;  1AS4 A;  2VH4 A;  1JJO C;  4DY0 A;  9API A;  2VDX A;  4AJU A;  2XN3 A;  1XU8 A;  1JMO A;  1OO8 A;  2WXY C;  1KCT A;  2XN6 A;  4RO9 A;  9PAI A;  2B4X I;  3FGQ A;  3UT3 A;  2BEH L;  1SNG A;  4C41 A;  5IO1 A;  3CVM A;  1JRR A;  1ATH A;  3Q02 A;  1ATT A;  3EVJ I;  4P0F A;  3F1S A;  2H4Q A;  3Q03 A;  3OZQ A;  1JTI A;  1B3K A;  2BEH I;  2RIV A;  1EZX A;  3T1P A;  2ZNH A;  4G8O A;  2WXZ C; 
#chains in the Genus database with same CATH topology
 3B9F I;  4AU3 A;  1K9O I;  2RIW A;  1UHG A;  4AQH A;  4AU2 A;  1JMJ A;  4ROA A;  4IF8 A;  7API A;  1LQ8 A;  3ZHA A;  1OVA A;  4AU4 A;  5INW A;  2WY0 C;  2ZV6 A;  1E04 I;  1DZH L;  1T1F A;  1PSI A;  1DVM A;  4EB1 L;  4X30 A;  3DLW A;  1WZ9 A;  2QUG A;  1XQJ A;  2ARR A;  2OAY A;  4ZK0 A;  3F02 A;  1DZH I;  5C98 A;  4KDS A;  4ROB A;  3NE4 A;  2WXW A;  3DRM A;  4EB1 I;  1M93 B;  1DZG L;  8API A;  3NDD A;  2H4P A;  2WXX A;  3NDA A;  3DY0 A;  1SR5 A;  2R9Y A;  1ANT I;  1IMV A;  4DTE A;  1OC0 A;  1QMB A;  3KCG I;  2D26 A;  1BY7 A;  1DZG I;  1OYH L;  2WXZ A;  1ATU A;  2ARQ A;  4ZK3 A;  3PZF A;  1A7C A;  1E05 I;  1NQ9 I;  2WY1 A;  1HLE A;  2OL2 A;  5CDX A;  1OPH A;  2GD4 C;  1MTP A;  1OYH I;  3R4L A;  1LJ5 A;  1YXA A;  4P0O A;  4AU3 B;  2XN7 A;  4YIA A;  5EI0 A;  3H5C A;  3NDF A;  1HP7 A;  2DUT A;  5HGC A;  2HIJ L;  1DVN A;  2H4R A;  2HI9 A;  1BR8 I;  3EOX A;  3F5N A;  3CWL A;  4R9I A;  1F0C A;  3VVJ A;  1C5G A;  1LK6 I;  1JVQ I;  4BB2 A;  2XN5 A;  2V95 A;  1QMN A;  2HIJ I;  4RSQ A;  1AZX I;  3CWM A;  1C8O A;  1R1L I;  4G8R A;  2PEE A;  1QLP A;  1TB6 I;  3CAA A;  4DY7 C;  1IZ2 A;  4IC0 A;  5CDZ A;  5CE0 A;  2VDY A;  1XQG A;  3PB1 I;  4GA7 A;  3DRU A;  3LW2 A;  4PYW A;  4Y40 A;  4AJT A;  2ANT I;  3STO A;  4AFX A;  2CEO A;  2PEF A;  4C49 A;  1D5S A;  4CAA A;  1OVA B;  1SEK A;  2ACH A;  5BRR I;  3LE2 A;  1DB2 A;  1E03 I;  1OVA C;  2B4X L;  2B5T I;  4Y3K A;  1AS4 A;  2VH4 A;  1JJO C;  4DY0 A;  9API A;  2VDX A;  4AJU A;  2XN3 A;  1XU8 A;  1JMO A;  1OO8 A;  2WXY C;  1KCT A;  2XN6 A;  4RO9 A;  9PAI A;  2B4X I;  3FGQ A;  3UT3 A;  2BEH L;  1SNG A;  4C41 A;  5IO1 A;  3CVM A;  1JRR A;  1ATH A;  3Q02 A;  1ATT A;  3EVJ I;  4P0F A;  3F1S A;  2H4Q A;  3Q03 A;  3OZQ A;  1JTI A;  1B3K A;  2BEH I;  2RIV A;  1EZX A;  3T1P A;  2ZNH A;  4G8O A;  2WXZ C; 
#chains in the Genus database with same CATH homology
 3B9F I;  4AU3 A;  1K9O I;  2RIW A;  1UHG A;  4AQH A;  4AU2 A;  1JMJ A;  4ROA A;  4IF8 A;  7API A;  1LQ8 A;  3ZHA A;  1OVA A;  4AU4 A;  5INW A;  2WY0 C;  2ZV6 A;  1E04 I;  1DZH L;  1T1F A;  1PSI A;  1DVM A;  4EB1 L;  4X30 A;  3DLW A;  1WZ9 A;  2QUG A;  1XQJ A;  2ARR A;  2OAY A;  4ZK0 A;  3F02 A;  1DZH I;  5C98 A;  4KDS A;  4ROB A;  3NE4 A;  2WXW A;  3DRM A;  4EB1 I;  1M93 B;  1DZG L;  8API A;  3NDD A;  2H4P A;  2WXX A;  3NDA A;  3DY0 A;  1SR5 A;  2R9Y A;  1ANT I;  1IMV A;  4DTE A;  1OC0 A;  1QMB A;  3KCG I;  2D26 A;  1BY7 A;  1DZG I;  1OYH L;  2WXZ A;  1ATU A;  2ARQ A;  4ZK3 A;  3PZF A;  1A7C A;  1E05 I;  1NQ9 I;  2WY1 A;  1HLE A;  2OL2 A;  5CDX A;  1OPH A;  2GD4 C;  1MTP A;  1OYH I;  3R4L A;  1LJ5 A;  1YXA A;  4P0O A;  4AU3 B;  2XN7 A;  4YIA A;  5EI0 A;  3H5C A;  3NDF A;  1HP7 A;  2DUT A;  5HGC A;  2HIJ L;  1DVN A;  2H4R A;  2HI9 A;  1BR8 I;  3EOX A;  3F5N A;  3CWL A;  4R9I A;  1F0C A;  3VVJ A;  1C5G A;  1LK6 I;  1JVQ I;  4BB2 A;  2XN5 A;  2V95 A;  1QMN A;  2HIJ I;  4RSQ A;  1AZX I;  3CWM A;  1C8O A;  1R1L I;  4G8R A;  2PEE A;  1QLP A;  1TB6 I;  3CAA A;  4DY7 C;  1IZ2 A;  4IC0 A;  5CDZ A;  5CE0 A;  2VDY A;  1XQG A;  3PB1 I;  4GA7 A;  3DRU A;  3LW2 A;  4PYW A;  4Y40 A;  4AJT A;  2ANT I;  3STO A;  4AFX A;  2CEO A;  2PEF A;  4C49 A;  1D5S A;  4CAA A;  1OVA B;  1SEK A;  2ACH A;  5BRR I;  3LE2 A;  1DB2 A;  1E03 I;  1OVA C;  2B4X L;  2B5T I;  4Y3K A;  1AS4 A;  2VH4 A;  1JJO C;  4DY0 A;  9API A;  2VDX A;  4AJU A;  2XN3 A;  1XU8 A;  1JMO A;  1OO8 A;  2WXY C;  1KCT A;  2XN6 A;  4RO9 A;  9PAI A;  2B4X I;  3FGQ A;  3UT3 A;  2BEH L;  1SNG A;  4C41 A;  5IO1 A;  3CVM A;  1JRR A;  1ATH A;  3Q02 A;  1ATT A;  3EVJ I;  4P0F A;  3F1S A;  2H4Q A;  3Q03 A;  3OZQ A;  1JTI A;  1B3K A;  2BEH I;  2RIV A;  1EZX A;  3T1P A;  2ZNH A;  4G8O A;  2WXZ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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