3OZQA

Crystal structure of serpin48, which is a highly specific serpin in the insect tenebrio molitor
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
376
structure length
364
Chain Sequence
GHMEDQEFPNAVNSFTPSVYKEVLKTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQVLHFVGDREKAEGAVKEVLSKLTNEEYTLHTANKIYVKTNFSVREEFQKIAVEVYGAQSENVDFSEKNDAAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFNAKWLVPFPPFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYECHHLDAKLLELPFKGGASLTIVLSNQIEGLVSLESKIKRSFLPHNLTKQLVNVALPKFKIESTVDFKKVLKKLGVKKAFGDEADLSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVSPKQFIVDHPFIFYIKVKGMILFAGRVTTLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional characterization of a highly specific serpin in the insect innate immunity
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Tenebrio molitor
molecule keywords Serpin48
total genus 101
structure length 364
sequence length 376
ec nomenclature
pdb deposition date 2010-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3ozqA01
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3ozqA02
2WY0C 3OZQA 7APIA 4Y3KA 4EB1L 1ATUA 9APIA 2CEOA 3KCGI 2D26A 2VH4A 3STOA 1M93B 3NE4A 4IC0A 2XN5A 1QLPA 2QUGA 3NDAA 1DZGL 1SNGA 2OL2A 1DZHI 1TB6I 3CWMA 2WY1A 3EVJI 3NDFA 5IO1A 2B4XL 1BR8I 1OYHI 4AFXA 1JMJA 3PZFA 2ZV6A 1AS4A 4ROBA 9PAIA 1XU8A 4AU3A 2ANTI 2VDXA 1JRRA 1KCTA 1DVMA 4AU3B 4EB1I 1D5SA 5HGCA 4DTEA 1XQGA 3F02A 2HI9A 1JJOC 3Q03A 1E04I 3VVJA 3NDDA 1DVNA 3F5NA 2DUTA 2GD4C 3PB1I 3CVMA 1DZGI 4G8RA 4C41A 2PEEA 3T1PA 1OC0A 1QMBA 2BEHL 2B4XI 1OVAA 2H4PA 4R9IA 4Y40A 4AQHA 4PYWA 1OVAB 4YIAA 5CDXA 1IMVA 4IF8A 1HLEA 2XN7A 4KDSA 5BRRI 1BY7A 1LK6I 1OPHA 5INWA 1ATTA 2ACHA 3UT3A 1EZXA 5CE0A 5CDZA 1B3KA 3DY0A 2V95A 1LJ5A 2H4QA 1K9OI 3LE2A 1C8OA 1OVAC 2BEHI 2PEFA 2WXZC 4RSQA 3CWLA 8APIA 3Q02A 3EOXA 4CAAA 2RIVA 5EI0A 3CAAA 1E05I 2WXWA 2WXZA 4ROAA 1HP7A 3DRUA 1C5GA 1WZ9A 1SR5A 1E03I 2HIJL 2XN3A 3DLWA 2WXXA 4DY0A 5C98A 4AJTA 1JTIA 1R1LI 4RO9A 3F1SA 3LW2A 2WXYC 1ANTI 1F0CA 2ARQA 3B9FI 1JMOA 4GA7A 3ZHAA 3DRMA 3H5CA 1MTPA 4P0FA 4X30A 4BB2A 1NQ9I 1YXAA 4C49A 2B5TI 2RIWA 2ZNHA 4G8OA 1DB2A 4ZK0A 1ATHA 1SEKA 2XN6A 4DY7C 1LQ8A 2HIJI 2VDYA 4P0OA 1T1FA 2OAYA 1AZXI 4AU4A 3FGQA 1PSIA 1XQJA 4AJUA 4AU2A 3R4LA 4ZK3A 1IZ2A 1DZHL 1QMNA 2ARRA 1UHGA 1A7CA 2H4RA 1OYHL 1OO8A 1JVQI 2R9YA
chains in the Genus database with same CATH superfamily
2WY0C 3OZQA 7APIA 4Y3KA 4EB1L 1ATUA 9APIA 2CEOA 3KCGI 2D26A 2VH4A 3STOA 1M93B 3NE4A 4IC0A 2XN5A 1QLPA 2QUGA 3NDAA 1DZGL 1SNGA 2OL2A 1DZHI 1TB6I 3CWMA 2WY1A 3EVJI 3NDFA 5IO1A 2B4XL 1BR8I 1OYHI 4AFXA 1JMJA 3PZFA 2ZV6A 1AS4A 4ROBA 9PAIA 1XU8A 4AU3A 2ANTI 2VDXA 1JRRA 1KCTA 1DVMA 4AU3B 4EB1I 1D5SA 5HGCA 4DTEA 1XQGA 3F02A 2HI9A 1JJOC 3Q03A 1E04I 3VVJA 3NDDA 1DVNA 3F5NA 2DUTA 2GD4C 3PB1I 3CVMA 1DZGI 4G8RA 4C41A 2PEEA 3T1PA 1OC0A 1QMBA 2BEHL 2B4XI 1OVAA 2H4PA 4R9IA 4Y40A 4AQHA 4PYWA 1OVAB 4YIAA 5CDXA 1IMVA 4IF8A 1HLEA 2XN7A 4KDSA 5BRRI 1BY7A 1LK6I 1OPHA 5INWA 1ATTA 2ACHA 3UT3A 1EZXA 5CE0A 5CDZA 1B3KA 3DY0A 2V95A 1LJ5A 2H4QA 1K9OI 3LE2A 1C8OA 1OVAC 2BEHI 2PEFA 2WXZC 4RSQA 3CWLA 8APIA 3Q02A 3EOXA 4CAAA 2RIVA 5EI0A 3CAAA 1E05I 2WXWA 2WXZA 4ROAA 1HP7A 3DRUA 1C5GA 1WZ9A 1SR5A 1E03I 2HIJL 2XN3A 3DLWA 2WXXA 4DY0A 5C98A 4AJTA 1JTIA 1R1LI 4RO9A 3F1SA 3LW2A 2WXYC 1ANTI 1F0CA 2ARQA 3B9FI 1JMOA 4GA7A 3ZHAA 3DRMA 3H5CA 1MTPA 4P0FA 4X30A 4BB2A 1NQ9I 1YXAA 4C49A 2B5TI 2RIWA 2ZNHA 4G8OA 1DB2A 4ZK0A 1ATHA 1SEKA 2XN6A 4DY7C 1LQ8A 2HIJI 2VDYA 4P0OA 1T1FA 2OAYA 1AZXI 4AU4A 3FGQA 1PSIA 1XQJA 4AJUA 4AU2A 3R4LA 4ZK3A 1IZ2A 1DZHL 1QMNA 2ARRA 1UHGA 1A7CA 2H4RA 1OYHL 1OO8A 1JVQI 2R9YA
chains in the Genus database with same CATH topology
2WY0C 3OZQA 7APIA 4Y3KA 4EB1L 1ATUA 9APIA 2CEOA 3KCGI 2D26A 2VH4A 3STOA 1M93B 3NE4A 4IC0A 2XN5A 1QLPA 2QUGA 3NDAA 1DZGL 1SNGA 2OL2A 1DZHI 1TB6I 3CWMA 2WY1A 3EVJI 3NDFA 5IO1A 2B4XL 1BR8I 1OYHI 4AFXA 1JMJA 3PZFA 2ZV6A 1AS4A 4ROBA 9PAIA 1XU8A 4AU3A 2ANTI 2VDXA 1JRRA 1KCTA 1DVMA 4AU3B 4EB1I 1D5SA 5HGCA 4DTEA 1XQGA 3F02A 2HI9A 1JJOC 3Q03A 1E04I 3VVJA 3NDDA 1DVNA 3F5NA 2DUTA 2GD4C 3PB1I 3CVMA 1DZGI 4G8RA 4C41A 2PEEA 3T1PA 1OC0A 1QMBA 2BEHL 2B4XI 1OVAA 2H4PA 4R9IA 4Y40A 4AQHA 4PYWA 1OVAB 4YIAA 5CDXA 1IMVA 4IF8A 1HLEA 2XN7A 4KDSA 5BRRI 1BY7A 1LK6I 1OPHA 5INWA 1ATTA 2ACHA 3UT3A 1EZXA 5CE0A 5CDZA 1B3KA 3DY0A 2V95A 1LJ5A 2H4QA 1K9OI 3LE2A 1C8OA 1OVAC 2BEHI 2PEFA 2WXZC 4RSQA 3CWLA 8APIA 3Q02A 3EOXA 4CAAA 2RIVA 5EI0A 3CAAA 1E05I 2WXWA 2WXZA 4ROAA 1HP7A 3DRUA 1C5GA 1WZ9A 1SR5A 1E03I 2HIJL 2XN3A 3DLWA 2WXXA 4DY0A 5C98A 4AJTA 1JTIA 1R1LI 4RO9A 3F1SA 3LW2A 2WXYC 1ANTI 1F0CA 2ARQA 3B9FI 1JMOA 4GA7A 3ZHAA 3DRMA 3H5CA 1MTPA 4P0FA 4X30A 4BB2A 1NQ9I 1YXAA 4C49A 2B5TI 2RIWA 2ZNHA 4G8OA 1DB2A 4ZK0A 1ATHA 1SEKA 2XN6A 4DY7C 1LQ8A 2HIJI 2VDYA 4P0OA 1T1FA 2OAYA 1AZXI 4AU4A 3FGQA 1PSIA 1XQJA 4AJUA 4AU2A 3R4LA 4ZK3A 1IZ2A 1DZHL 1QMNA 2ARRA 1UHGA 1A7CA 2H4RA 1OYHL 1OO8A 1JVQI 2R9YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WY0 C;  3OZQ A;  7API A;  4Y3K A;  4EB1 L;  1ATU A;  9API A;  2CEO A;  3KCG I;  2D26 A;  2VH4 A;  3STO A;  1M93 B;  3NE4 A;  4IC0 A;  2XN5 A;  1QLP A;  2QUG A;  3NDA A;  1DZG L;  1SNG A;  2OL2 A;  1DZH I;  1TB6 I;  3CWM A;  2WY1 A;  3EVJ I;  3NDF A;  5IO1 A;  2B4X L;  1BR8 I;  1OYH I;  4AFX A;  1JMJ A;  3PZF A;  2ZV6 A;  1AS4 A;  4ROB A;  9PAI A;  1XU8 A;  4AU3 A;  2ANT I;  2VDX A;  1JRR A;  1KCT A;  1DVM A;  4AU3 B;  4EB1 I;  1D5S A;  5HGC A;  4DTE A;  1XQG A;  3F02 A;  2HI9 A;  1JJO C;  3Q03 A;  1E04 I;  3VVJ A;  3NDD A;  1DVN A;  3F5N A;  2DUT A;  2GD4 C;  3PB1 I;  3CVM A;  1DZG I;  4G8R A;  4C41 A;  2PEE A;  3T1P A;  1OC0 A;  1QMB A;  2BEH L;  2B4X I;  1OVA A;  2H4P A;  4R9I A;  4Y40 A;  4AQH A;  4PYW A;  1OVA B;  4YIA A;  5CDX A;  1IMV A;  4IF8 A;  1HLE A;  2XN7 A;  4KDS A;  5BRR I;  1BY7 A;  1LK6 I;  1OPH A;  5INW A;  1ATT A;  2ACH A;  3UT3 A;  1EZX A;  5CE0 A;  5CDZ A;  1B3K A;  3DY0 A;  2V95 A;  1LJ5 A;  2H4Q A;  1K9O I;  3LE2 A;  1C8O A;  1OVA C;  2BEH I;  2PEF A;  2WXZ C;  4RSQ A;  3CWL A;  8API A;  3Q02 A;  3EOX A;  4CAA A;  2RIV A;  5EI0 A;  3CAA A;  1E05 I;  2WXW A;  2WXZ A;  4ROA A;  1HP7 A;  3DRU A;  1C5G A;  1WZ9 A;  1SR5 A;  1E03 I;  2HIJ L;  2XN3 A;  3DLW A;  2WXX A;  4DY0 A;  5C98 A;  4AJT A;  1JTI A;  1R1L I;  4RO9 A;  3F1S A;  3LW2 A;  2WXY C;  1ANT I;  1F0C A;  2ARQ A;  3B9F I;  1JMO A;  4GA7 A;  3ZHA A;  3DRM A;  3H5C A;  1MTP A;  4P0F A;  4X30 A;  4BB2 A;  1NQ9 I;  1YXA A;  4C49 A;  2B5T I;  2RIW A;  2ZNH A;  4G8O A;  1DB2 A;  4ZK0 A;  1ATH A;  1SEK A;  2XN6 A;  4DY7 C;  1LQ8 A;  2HIJ I;  2VDY A;  4P0O A;  1T1F A;  2OAY A;  1AZX I;  4AU4 A;  3FGQ A;  1PSI A;  1XQJ A;  4AJU A;  4AU2 A;  3R4L A;  4ZK3 A;  1IZ2 A;  1DZH L;  1QMN A;  2ARR A;  1UHG A;  1A7C A;  2H4R A;  1OYH L;  1OO8 A;  1JVQ I;  2R9Y A; 
#chains in the Genus database with same CATH topology
 2WY0 C;  3OZQ A;  7API A;  4Y3K A;  4EB1 L;  1ATU A;  9API A;  2CEO A;  3KCG I;  2D26 A;  2VH4 A;  3STO A;  1M93 B;  3NE4 A;  4IC0 A;  2XN5 A;  1QLP A;  2QUG A;  3NDA A;  1DZG L;  1SNG A;  2OL2 A;  1DZH I;  1TB6 I;  3CWM A;  2WY1 A;  3EVJ I;  3NDF A;  5IO1 A;  2B4X L;  1BR8 I;  1OYH I;  4AFX A;  1JMJ A;  3PZF A;  2ZV6 A;  1AS4 A;  4ROB A;  9PAI A;  1XU8 A;  4AU3 A;  2ANT I;  2VDX A;  1JRR A;  1KCT A;  1DVM A;  4AU3 B;  4EB1 I;  1D5S A;  5HGC A;  4DTE A;  1XQG A;  3F02 A;  2HI9 A;  1JJO C;  3Q03 A;  1E04 I;  3VVJ A;  3NDD A;  1DVN A;  3F5N A;  2DUT A;  2GD4 C;  3PB1 I;  3CVM A;  1DZG I;  4G8R A;  4C41 A;  2PEE A;  3T1P A;  1OC0 A;  1QMB A;  2BEH L;  2B4X I;  1OVA A;  2H4P A;  4R9I A;  4Y40 A;  4AQH A;  4PYW A;  1OVA B;  4YIA A;  5CDX A;  1IMV A;  4IF8 A;  1HLE A;  2XN7 A;  4KDS A;  5BRR I;  1BY7 A;  1LK6 I;  1OPH A;  5INW A;  1ATT A;  2ACH A;  3UT3 A;  1EZX A;  5CE0 A;  5CDZ A;  1B3K A;  3DY0 A;  2V95 A;  1LJ5 A;  2H4Q A;  1K9O I;  3LE2 A;  1C8O A;  1OVA C;  2BEH I;  2PEF A;  2WXZ C;  4RSQ A;  3CWL A;  8API A;  3Q02 A;  3EOX A;  4CAA A;  2RIV A;  5EI0 A;  3CAA A;  1E05 I;  2WXW A;  2WXZ A;  4ROA A;  1HP7 A;  3DRU A;  1C5G A;  1WZ9 A;  1SR5 A;  1E03 I;  2HIJ L;  2XN3 A;  3DLW A;  2WXX A;  4DY0 A;  5C98 A;  4AJT A;  1JTI A;  1R1L I;  4RO9 A;  3F1S A;  3LW2 A;  2WXY C;  1ANT I;  1F0C A;  2ARQ A;  3B9F I;  1JMO A;  4GA7 A;  3ZHA A;  3DRM A;  3H5C A;  1MTP A;  4P0F A;  4X30 A;  4BB2 A;  1NQ9 I;  1YXA A;  4C49 A;  2B5T I;  2RIW A;  2ZNH A;  4G8O A;  1DB2 A;  4ZK0 A;  1ATH A;  1SEK A;  2XN6 A;  4DY7 C;  1LQ8 A;  2HIJ I;  2VDY A;  4P0O A;  1T1F A;  2OAY A;  1AZX I;  4AU4 A;  3FGQ A;  1PSI A;  1XQJ A;  4AJU A;  4AU2 A;  3R4L A;  4ZK3 A;  1IZ2 A;  1DZH L;  1QMN A;  2ARR A;  1UHG A;  1A7C A;  2H4R A;  1OYH L;  1OO8 A;  1JVQ I;  2R9Y A; 
#chains in the Genus database with same CATH homology
 2WY0 C;  3OZQ A;  7API A;  4Y3K A;  4EB1 L;  1ATU A;  9API A;  2CEO A;  3KCG I;  2D26 A;  2VH4 A;  3STO A;  1M93 B;  3NE4 A;  4IC0 A;  2XN5 A;  1QLP A;  2QUG A;  3NDA A;  1DZG L;  1SNG A;  2OL2 A;  1DZH I;  1TB6 I;  3CWM A;  2WY1 A;  3EVJ I;  3NDF A;  5IO1 A;  2B4X L;  1BR8 I;  1OYH I;  4AFX A;  1JMJ A;  3PZF A;  2ZV6 A;  1AS4 A;  4ROB A;  9PAI A;  1XU8 A;  4AU3 A;  2ANT I;  2VDX A;  1JRR A;  1KCT A;  1DVM A;  4AU3 B;  4EB1 I;  1D5S A;  5HGC A;  4DTE A;  1XQG A;  3F02 A;  2HI9 A;  1JJO C;  3Q03 A;  1E04 I;  3VVJ A;  3NDD A;  1DVN A;  3F5N A;  2DUT A;  2GD4 C;  3PB1 I;  3CVM A;  1DZG I;  4G8R A;  4C41 A;  2PEE A;  3T1P A;  1OC0 A;  1QMB A;  2BEH L;  2B4X I;  1OVA A;  2H4P A;  4R9I A;  4Y40 A;  4AQH A;  4PYW A;  1OVA B;  4YIA A;  5CDX A;  1IMV A;  4IF8 A;  1HLE A;  2XN7 A;  4KDS A;  5BRR I;  1BY7 A;  1LK6 I;  1OPH A;  5INW A;  1ATT A;  2ACH A;  3UT3 A;  1EZX A;  5CE0 A;  5CDZ A;  1B3K A;  3DY0 A;  2V95 A;  1LJ5 A;  2H4Q A;  1K9O I;  3LE2 A;  1C8O A;  1OVA C;  2BEH I;  2PEF A;  2WXZ C;  4RSQ A;  3CWL A;  8API A;  3Q02 A;  3EOX A;  4CAA A;  2RIV A;  5EI0 A;  3CAA A;  1E05 I;  2WXW A;  2WXZ A;  4ROA A;  1HP7 A;  3DRU A;  1C5G A;  1WZ9 A;  1SR5 A;  1E03 I;  2HIJ L;  2XN3 A;  3DLW A;  2WXX A;  4DY0 A;  5C98 A;  4AJT A;  1JTI A;  1R1L I;  4RO9 A;  3F1S A;  3LW2 A;  2WXY C;  1ANT I;  1F0C A;  2ARQ A;  3B9F I;  1JMO A;  4GA7 A;  3ZHA A;  3DRM A;  3H5C A;  1MTP A;  4P0F A;  4X30 A;  4BB2 A;  1NQ9 I;  1YXA A;  4C49 A;  2B5T I;  2RIW A;  2ZNH A;  4G8O A;  1DB2 A;  4ZK0 A;  1ATH A;  1SEK A;  2XN6 A;  4DY7 C;  1LQ8 A;  2HIJ I;  2VDY A;  4P0O A;  1T1F A;  2OAY A;  1AZX I;  4AU4 A;  3FGQ A;  1PSI A;  1XQJ A;  4AJU A;  4AU2 A;  3R4L A;  4ZK3 A;  1IZ2 A;  1DZH L;  1QMN A;  2ARR A;  1UHG A;  1A7C A;  2H4R A;  1OYH L;  1OO8 A;  1JVQ I;  2R9Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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