3STOA

Serpin from the trematode schistosoma haematobium
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
388
structure length
370
Chain Sequence
ISSHKAFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLEENVVRISTGIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Schistosoma haematobium
molecule keywords Serine protease inhibitor
total genus 113
structure length 370
sequence length 388
ec nomenclature
pdb deposition date 2011-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3stoA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3stoA01
3B9FI 4AFXA 2GD4C 2H4RA 1DVMA 3LE2A 4P0OA 1JTIA 4DTEA 2BEHI 2XN3A 3Q03A 1E04I 3CVMA 2HIJI 2OL2A 1QMBA 3CAAA 1JVQI 1E03I 1ATHA 2XN6A 1TB6I 2ZNHA 3VVJA 1QLPA 4AJUA 2ANTI 3DRMA 4EB1L 1DB2A 4C49A 3ZHAA 5EI0A 1A7CA 1KCTA 2V95A 4C41A 2WXWA 1E05I 1HP7A 1D5SA 4ROAA 1XQJA 4CAAA 1IZ2A 2RIVA 2ARQA 3DY0A 1F0CA 4Y40A 3Q02A 1XQGA 1QMNA 2BEHL 4PYWA 8APIA 3EVJI 3PB1I 2H4PA 2HIJL 4IF8A 4ZK3A 2XN7A 4G8OA 4Y3KA 1LJ5A 1PSIA 2R9YA 2H4QA 2WXYC 3EOXA 3T1PA 1C5GA 2B4XI 1SR5A 2QUGA 4R9IA 3F1SA 2ZV6A 3NDAA 4AQHA 1ANTI 5HGCA 2B5TI 1IMVA 5BRRI 4BB2A 3LW2A 3DLWA 4KDSA 3F5NA 1ATUA 4AJTA 1SNGA 1XU8A 4G8RA 3NDDA 4AU4A 2ACHA 2XN5A 3NDFA 1OVAC 1DZGI 4IC0A 2WXZC 4DY0A 4YIAA 1UHGA 4RO9A 3NE4A 2PEFA 2ARRA 1BY7A 7APIA 5IO1A 3PZFA 1OYHI 2B4XL 1SEKA 4DY7C 1OVAB 4EB1I 4ZK0A 2VDXA 1DZHI 4P0FA 9APIA 1JRRA 2CEOA 1AS4A 4AU3B 4AU2A 3F02A 5C98A 3OZQA 1MTPA 1T1FA 3CWMA 1OVAA 5CDXA 1K9OI 1ATTA 4ROBA 3CWLA 2WXZA 5CDZA 1OO8A 4AU3A 1EZXA 1C8OA 3R4LA 3H5CA 2OAYA 3FGQA 1OPHA 1AZXI 1DZGL 3KCGI 4X30A 1OC0A 5INWA 4GA7A 4RSQA 1JMJA 1DVNA 1R1LI 2WY0C 1HLEA 3UT3A 1LQ8A 1OYHL 2VH4A 1YXAA 9PAIA 1LK6I 2RIWA 2DUTA 1BR8I 2WY1A 1JJOC 3DRUA 2VDYA 1DZHL 5CE0A 2WXXA 2D26A 1M93B 1WZ9A 3STOA 2PEEA 1NQ9I 2HI9A 1B3KA 1JMOA
chains in the Genus database with same CATH superfamily
3B9FI 4AFXA 2GD4C 2H4RA 1DVMA 3LE2A 4P0OA 1JTIA 4DTEA 2BEHI 2XN3A 3Q03A 1E04I 3CVMA 2HIJI 2OL2A 1QMBA 3CAAA 1JVQI 1E03I 1ATHA 2XN6A 1TB6I 2ZNHA 3VVJA 1QLPA 4AJUA 2ANTI 3DRMA 4EB1L 1DB2A 4C49A 3ZHAA 5EI0A 1A7CA 1KCTA 2V95A 4C41A 2WXWA 1E05I 1HP7A 1D5SA 4ROAA 1XQJA 4CAAA 1IZ2A 2RIVA 2ARQA 3DY0A 1F0CA 4Y40A 3Q02A 1XQGA 1QMNA 2BEHL 4PYWA 8APIA 3EVJI 3PB1I 2H4PA 2HIJL 4IF8A 4ZK3A 2XN7A 4G8OA 4Y3KA 1LJ5A 1PSIA 2R9YA 2H4QA 2WXYC 3EOXA 3T1PA 1C5GA 2B4XI 1SR5A 2QUGA 4R9IA 3F1SA 2ZV6A 3NDAA 4AQHA 1ANTI 5HGCA 2B5TI 1IMVA 5BRRI 4BB2A 3LW2A 3DLWA 4KDSA 3F5NA 1ATUA 4AJTA 1SNGA 1XU8A 4G8RA 3NDDA 4AU4A 2ACHA 2XN5A 3NDFA 1OVAC 1DZGI 4IC0A 2WXZC 4DY0A 4YIAA 1UHGA 4RO9A 3NE4A 2PEFA 2ARRA 1BY7A 7APIA 5IO1A 3PZFA 1OYHI 2B4XL 1SEKA 4DY7C 1OVAB 4EB1I 4ZK0A 2VDXA 1DZHI 4P0FA 9APIA 1JRRA 2CEOA 1AS4A 4AU3B 4AU2A 3F02A 5C98A 3OZQA 1MTPA 1T1FA 3CWMA 1OVAA 5CDXA 1K9OI 1ATTA 4ROBA 3CWLA 2WXZA 5CDZA 1OO8A 4AU3A 1EZXA 1C8OA 3R4LA 3H5CA 2OAYA 3FGQA 1OPHA 1AZXI 1DZGL 3KCGI 4X30A 1OC0A 5INWA 4GA7A 4RSQA 1JMJA 1DVNA 1R1LI 2WY0C 1HLEA 3UT3A 1LQ8A 1OYHL 2VH4A 1YXAA 9PAIA 1LK6I 2RIWA 2DUTA 1BR8I 2WY1A 1JJOC 3DRUA 2VDYA 1DZHL 5CE0A 2WXXA 2D26A 1M93B 1WZ9A 3STOA 2PEEA 1NQ9I 2HI9A 1B3KA 1JMOA
chains in the Genus database with same CATH topology
3B9FI 4AFXA 2GD4C 2H4RA 1DVMA 3LE2A 4P0OA 1JTIA 4DTEA 2BEHI 2XN3A 3Q03A 1E04I 3CVMA 2HIJI 2OL2A 1QMBA 3CAAA 1JVQI 1E03I 1ATHA 2XN6A 1TB6I 2ZNHA 3VVJA 1QLPA 4AJUA 2ANTI 3DRMA 4EB1L 1DB2A 4C49A 3ZHAA 5EI0A 1A7CA 1KCTA 2V95A 4C41A 2WXWA 1E05I 1HP7A 1D5SA 4ROAA 1XQJA 4CAAA 1IZ2A 2RIVA 2ARQA 3DY0A 1F0CA 4Y40A 3Q02A 1XQGA 1QMNA 2BEHL 4PYWA 8APIA 3EVJI 3PB1I 2H4PA 2HIJL 4IF8A 4ZK3A 2XN7A 4G8OA 4Y3KA 1LJ5A 1PSIA 2R9YA 2H4QA 2WXYC 3EOXA 3T1PA 1C5GA 2B4XI 1SR5A 2QUGA 4R9IA 3F1SA 2ZV6A 3NDAA 4AQHA 1ANTI 5HGCA 2B5TI 1IMVA 5BRRI 4BB2A 3LW2A 3DLWA 4KDSA 3F5NA 1ATUA 4AJTA 1SNGA 1XU8A 4G8RA 3NDDA 4AU4A 2ACHA 2XN5A 3NDFA 1OVAC 1DZGI 4IC0A 2WXZC 4DY0A 4YIAA 1UHGA 4RO9A 3NE4A 2PEFA 2ARRA 1BY7A 7APIA 5IO1A 3PZFA 1OYHI 2B4XL 1SEKA 4DY7C 1OVAB 4EB1I 4ZK0A 2VDXA 1DZHI 4P0FA 9APIA 1JRRA 2CEOA 1AS4A 4AU3B 4AU2A 3F02A 5C98A 3OZQA 1MTPA 1T1FA 3CWMA 1OVAA 5CDXA 1K9OI 1ATTA 4ROBA 3CWLA 2WXZA 5CDZA 1OO8A 4AU3A 1EZXA 1C8OA 3R4LA 3H5CA 2OAYA 3FGQA 1OPHA 1AZXI 1DZGL 3KCGI 4X30A 1OC0A 5INWA 4GA7A 4RSQA 1JMJA 1DVNA 1R1LI 2WY0C 1HLEA 3UT3A 1LQ8A 1OYHL 2VH4A 1YXAA 9PAIA 1LK6I 2RIWA 2DUTA 1BR8I 2WY1A 1JJOC 3DRUA 2VDYA 1DZHL 5CE0A 2WXXA 2D26A 1M93B 1WZ9A 3STOA 2PEEA 1NQ9I 2HI9A 1B3KA 1JMOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B9F I;  4AFX A;  2GD4 C;  2H4R A;  1DVM A;  3LE2 A;  4P0O A;  1JTI A;  4DTE A;  2BEH I;  2XN3 A;  3Q03 A;  1E04 I;  3CVM A;  2HIJ I;  2OL2 A;  1QMB A;  3CAA A;  1JVQ I;  1E03 I;  1ATH A;  2XN6 A;  1TB6 I;  2ZNH A;  3VVJ A;  1QLP A;  4AJU A;  2ANT I;  3DRM A;  4EB1 L;  1DB2 A;  4C49 A;  3ZHA A;  5EI0 A;  1A7C A;  1KCT A;  2V95 A;  4C41 A;  2WXW A;  1E05 I;  1HP7 A;  1D5S A;  4ROA A;  1XQJ A;  4CAA A;  1IZ2 A;  2RIV A;  2ARQ A;  3DY0 A;  1F0C A;  4Y40 A;  3Q02 A;  1XQG A;  1QMN A;  2BEH L;  4PYW A;  8API A;  3EVJ I;  3PB1 I;  2H4P A;  2HIJ L;  4IF8 A;  4ZK3 A;  2XN7 A;  4G8O A;  4Y3K A;  1LJ5 A;  1PSI A;  2R9Y A;  2H4Q A;  2WXY C;  3EOX A;  3T1P A;  1C5G A;  2B4X I;  1SR5 A;  2QUG A;  4R9I A;  3F1S A;  2ZV6 A;  3NDA A;  4AQH A;  1ANT I;  5HGC A;  2B5T I;  1IMV A;  5BRR I;  4BB2 A;  3LW2 A;  3DLW A;  4KDS A;  3F5N A;  1ATU A;  4AJT A;  1SNG A;  1XU8 A;  4G8R A;  3NDD A;  4AU4 A;  2ACH A;  2XN5 A;  3NDF A;  1OVA C;  1DZG I;  4IC0 A;  2WXZ C;  4DY0 A;  4YIA A;  1UHG A;  4RO9 A;  3NE4 A;  2PEF A;  2ARR A;  1BY7 A;  7API A;  5IO1 A;  3PZF A;  1OYH I;  2B4X L;  1SEK A;  4DY7 C;  1OVA B;  4EB1 I;  4ZK0 A;  2VDX A;  1DZH I;  4P0F A;  9API A;  1JRR A;  2CEO A;  1AS4 A;  4AU3 B;  4AU2 A;  3F02 A;  5C98 A;  3OZQ A;  1MTP A;  1T1F A;  3CWM A;  1OVA A;  5CDX A;  1K9O I;  1ATT A;  4ROB A;  3CWL A;  2WXZ A;  5CDZ A;  1OO8 A;  4AU3 A;  1EZX A;  1C8O A;  3R4L A;  3H5C A;  2OAY A;  3FGQ A;  1OPH A;  1AZX I;  1DZG L;  3KCG I;  4X30 A;  1OC0 A;  5INW A;  4GA7 A;  4RSQ A;  1JMJ A;  1DVN A;  1R1L I;  2WY0 C;  1HLE A;  3UT3 A;  1LQ8 A;  1OYH L;  2VH4 A;  1YXA A;  9PAI A;  1LK6 I;  2RIW A;  2DUT A;  1BR8 I;  2WY1 A;  1JJO C;  3DRU A;  2VDY A;  1DZH L;  5CE0 A;  2WXX A;  2D26 A;  1M93 B;  1WZ9 A;  3STO A;  2PEE A;  1NQ9 I;  2HI9 A;  1B3K A;  1JMO A; 
#chains in the Genus database with same CATH topology
 3B9F I;  4AFX A;  2GD4 C;  2H4R A;  1DVM A;  3LE2 A;  4P0O A;  1JTI A;  4DTE A;  2BEH I;  2XN3 A;  3Q03 A;  1E04 I;  3CVM A;  2HIJ I;  2OL2 A;  1QMB A;  3CAA A;  1JVQ I;  1E03 I;  1ATH A;  2XN6 A;  1TB6 I;  2ZNH A;  3VVJ A;  1QLP A;  4AJU A;  2ANT I;  3DRM A;  4EB1 L;  1DB2 A;  4C49 A;  3ZHA A;  5EI0 A;  1A7C A;  1KCT A;  2V95 A;  4C41 A;  2WXW A;  1E05 I;  1HP7 A;  1D5S A;  4ROA A;  1XQJ A;  4CAA A;  1IZ2 A;  2RIV A;  2ARQ A;  3DY0 A;  1F0C A;  4Y40 A;  3Q02 A;  1XQG A;  1QMN A;  2BEH L;  4PYW A;  8API A;  3EVJ I;  3PB1 I;  2H4P A;  2HIJ L;  4IF8 A;  4ZK3 A;  2XN7 A;  4G8O A;  4Y3K A;  1LJ5 A;  1PSI A;  2R9Y A;  2H4Q A;  2WXY C;  3EOX A;  3T1P A;  1C5G A;  2B4X I;  1SR5 A;  2QUG A;  4R9I A;  3F1S A;  2ZV6 A;  3NDA A;  4AQH A;  1ANT I;  5HGC A;  2B5T I;  1IMV A;  5BRR I;  4BB2 A;  3LW2 A;  3DLW A;  4KDS A;  3F5N A;  1ATU A;  4AJT A;  1SNG A;  1XU8 A;  4G8R A;  3NDD A;  4AU4 A;  2ACH A;  2XN5 A;  3NDF A;  1OVA C;  1DZG I;  4IC0 A;  2WXZ C;  4DY0 A;  4YIA A;  1UHG A;  4RO9 A;  3NE4 A;  2PEF A;  2ARR A;  1BY7 A;  7API A;  5IO1 A;  3PZF A;  1OYH I;  2B4X L;  1SEK A;  4DY7 C;  1OVA B;  4EB1 I;  4ZK0 A;  2VDX A;  1DZH I;  4P0F A;  9API A;  1JRR A;  2CEO A;  1AS4 A;  4AU3 B;  4AU2 A;  3F02 A;  5C98 A;  3OZQ A;  1MTP A;  1T1F A;  3CWM A;  1OVA A;  5CDX A;  1K9O I;  1ATT A;  4ROB A;  3CWL A;  2WXZ A;  5CDZ A;  1OO8 A;  4AU3 A;  1EZX A;  1C8O A;  3R4L A;  3H5C A;  2OAY A;  3FGQ A;  1OPH A;  1AZX I;  1DZG L;  3KCG I;  4X30 A;  1OC0 A;  5INW A;  4GA7 A;  4RSQ A;  1JMJ A;  1DVN A;  1R1L I;  2WY0 C;  1HLE A;  3UT3 A;  1LQ8 A;  1OYH L;  2VH4 A;  1YXA A;  9PAI A;  1LK6 I;  2RIW A;  2DUT A;  1BR8 I;  2WY1 A;  1JJO C;  3DRU A;  2VDY A;  1DZH L;  5CE0 A;  2WXX A;  2D26 A;  1M93 B;  1WZ9 A;  3STO A;  2PEE A;  1NQ9 I;  2HI9 A;  1B3K A;  1JMO A; 
#chains in the Genus database with same CATH homology
 3B9F I;  4AFX A;  2GD4 C;  2H4R A;  1DVM A;  3LE2 A;  4P0O A;  1JTI A;  4DTE A;  2BEH I;  2XN3 A;  3Q03 A;  1E04 I;  3CVM A;  2HIJ I;  2OL2 A;  1QMB A;  3CAA A;  1JVQ I;  1E03 I;  1ATH A;  2XN6 A;  1TB6 I;  2ZNH A;  3VVJ A;  1QLP A;  4AJU A;  2ANT I;  3DRM A;  4EB1 L;  1DB2 A;  4C49 A;  3ZHA A;  5EI0 A;  1A7C A;  1KCT A;  2V95 A;  4C41 A;  2WXW A;  1E05 I;  1HP7 A;  1D5S A;  4ROA A;  1XQJ A;  4CAA A;  1IZ2 A;  2RIV A;  2ARQ A;  3DY0 A;  1F0C A;  4Y40 A;  3Q02 A;  1XQG A;  1QMN A;  2BEH L;  4PYW A;  8API A;  3EVJ I;  3PB1 I;  2H4P A;  2HIJ L;  4IF8 A;  4ZK3 A;  2XN7 A;  4G8O A;  4Y3K A;  1LJ5 A;  1PSI A;  2R9Y A;  2H4Q A;  2WXY C;  3EOX A;  3T1P A;  1C5G A;  2B4X I;  1SR5 A;  2QUG A;  4R9I A;  3F1S A;  2ZV6 A;  3NDA A;  4AQH A;  1ANT I;  5HGC A;  2B5T I;  1IMV A;  5BRR I;  4BB2 A;  3LW2 A;  3DLW A;  4KDS A;  3F5N A;  1ATU A;  4AJT A;  1SNG A;  1XU8 A;  4G8R A;  3NDD A;  4AU4 A;  2ACH A;  2XN5 A;  3NDF A;  1OVA C;  1DZG I;  4IC0 A;  2WXZ C;  4DY0 A;  4YIA A;  1UHG A;  4RO9 A;  3NE4 A;  2PEF A;  2ARR A;  1BY7 A;  7API A;  5IO1 A;  3PZF A;  1OYH I;  2B4X L;  1SEK A;  4DY7 C;  1OVA B;  4EB1 I;  4ZK0 A;  2VDX A;  1DZH I;  4P0F A;  9API A;  1JRR A;  2CEO A;  1AS4 A;  4AU3 B;  4AU2 A;  3F02 A;  5C98 A;  3OZQ A;  1MTP A;  1T1F A;  3CWM A;  1OVA A;  5CDX A;  1K9O I;  1ATT A;  4ROB A;  3CWL A;  2WXZ A;  5CDZ A;  1OO8 A;  4AU3 A;  1EZX A;  1C8O A;  3R4L A;  3H5C A;  2OAY A;  3FGQ A;  1OPH A;  1AZX I;  1DZG L;  3KCG I;  4X30 A;  1OC0 A;  5INW A;  4GA7 A;  4RSQ A;  1JMJ A;  1DVN A;  1R1L I;  2WY0 C;  1HLE A;  3UT3 A;  1LQ8 A;  1OYH L;  2VH4 A;  1YXA A;  9PAI A;  1LK6 I;  2RIW A;  2DUT A;  1BR8 I;  2WY1 A;  1JJO C;  3DRU A;  2VDY A;  1DZH L;  5CE0 A;  2WXX A;  2D26 A;  1M93 B;  1WZ9 A;  3STO A;  2PEE A;  1NQ9 I;  2HI9 A;  1B3K A;  1JMO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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