3STOA

Serpin from the trematode schistosoma haematobium
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
388
structure length
370
Chain Sequence
ISSHKAFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLEENVVRISTGIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
pubmed doi rcsb
molecule tags Hydrolase inhibitor
source organism Schistosoma haematobium
molecule keywords Serine protease inhibitor
total genus 113
structure length 370
sequence length 388
ec nomenclature
pdb deposition date 2011-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3stoA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3stoA01
2ZV6A 3NDDA 5CDZA 1ANTI 9APIA 1JMOA 2BEHI 3Q02A 2RIWA 2B4XI 3DRUA 3R4LA 4RSQA 3F1SA 4R9IA 2XN3A 1C8OA 1QLPA 5EI0A 1E05I 2ANTI 4X30A 1HLEA 1TB6I 2H4QA 3F02A 2R9YA 2RIVA 3NE4A 1OVAC 2VDYA 1QMNA 4AJUA 3LE2A 2CEOA 1DVNA 4AU2A 4C49A 9PAIA 1M93B 4IF8A 3UT3A 3FGQA 1XQJA 1HP7A 3Q03A 1ATUA 4Y40A 1PSIA 1YXAA 1LJ5A 3CAAA 4AU4A 2H4RA 1OO8A 1DZGI 4DY0A 1JTIA 1QMBA 4EB1I 4YIAA 4BB2A 3B9FI 1D5SA 2VDXA 2ARQA 3CVMA 4G8OA 3F5NA 2HIJI 2ARRA 2VH4A 5CE0A 8APIA 3DLWA 1OYHI 2BEHL 4IC0A 4C41A 3KCGI 4Y3KA 2B5TI 1UHGA 2ACHA 5C98A 1JMJA 2B4XL 2QUGA 1R1LI 1DZHI 1ATHA 3PB1I 4ZK3A 4AQHA 1JJOC 1OC0A 2WXZA 1OPHA 3STOA 1EZXA 1LK6I 1DB2A 3DRMA 3ZHAA 2WXWA 2GD4C 4KDSA 4P0OA 1IMVA 2D26A 1BY7A 7APIA 2XN7A 1A7CA 3CWLA 2OAYA 2PEEA 3H5CA 1KCTA 1DVMA 5IO1A 1BR8I 3EOXA 5HGCA 1OVAB 4RO9A 3EVJI 4GA7A 2WY1A 3CWMA 4DY7C 1K9OI 1ATTA 2XN5A 3VVJA 5INWA 5CDXA 1DZGL 3PZFA 1MTPA 4EB1L 4AU3B 1IZ2A 1F0CA 1AZXI 2H4PA 4AJTA 2XN6A 4ROBA 1JRRA 1B3KA 1WZ9A 3LW2A 2HIJL 1C5GA 2OL2A 1OYHL 1XQGA 3NDFA 1OVAA 3T1PA 1SR5A 4AFXA 1T1FA 4ROAA 1AS4A 3DY0A 2WXZC 2DUTA 1DZHL 3NDAA 2V95A 2ZNHA 4PYWA 1SNGA 2WXXA 2WXYC 1JVQI 5BRRI 2PEFA 4DTEA 4CAAA 4AU3A 2HI9A 2WY0C 1NQ9I 1E04I 4G8RA 4P0FA 4ZK0A 3OZQA 1XU8A 1LQ8A 1E03I 1SEKA
chains in the Genus database with same CATH superfamily
2ZV6A 3NDDA 5CDZA 1ANTI 9APIA 1JMOA 2BEHI 3Q02A 2RIWA 2B4XI 3DRUA 3R4LA 4RSQA 3F1SA 4R9IA 2XN3A 1C8OA 1QLPA 5EI0A 1E05I 2ANTI 4X30A 1HLEA 1TB6I 2H4QA 3F02A 2R9YA 2RIVA 3NE4A 1OVAC 2VDYA 1QMNA 4AJUA 3LE2A 2CEOA 1DVNA 4AU2A 4C49A 9PAIA 1M93B 4IF8A 3UT3A 3FGQA 1XQJA 1HP7A 3Q03A 1ATUA 4Y40A 1PSIA 1YXAA 1LJ5A 3CAAA 4AU4A 2H4RA 1OO8A 1DZGI 4DY0A 1JTIA 1QMBA 4EB1I 4YIAA 4BB2A 3B9FI 1D5SA 2VDXA 2ARQA 3CVMA 4G8OA 3F5NA 2HIJI 2ARRA 2VH4A 5CE0A 8APIA 3DLWA 1OYHI 2BEHL 4IC0A 4C41A 3KCGI 4Y3KA 2B5TI 1UHGA 2ACHA 5C98A 1JMJA 2B4XL 2QUGA 1R1LI 1DZHI 1ATHA 3PB1I 4ZK3A 4AQHA 1JJOC 1OC0A 2WXZA 1OPHA 3STOA 1EZXA 1LK6I 1DB2A 3DRMA 3ZHAA 2WXWA 2GD4C 4KDSA 4P0OA 1IMVA 2D26A 1BY7A 7APIA 2XN7A 1A7CA 3CWLA 2OAYA 2PEEA 3H5CA 1KCTA 1DVMA 5IO1A 1BR8I 3EOXA 5HGCA 1OVAB 4RO9A 3EVJI 4GA7A 2WY1A 3CWMA 4DY7C 1K9OI 1ATTA 2XN5A 3VVJA 5INWA 5CDXA 1DZGL 3PZFA 1MTPA 4EB1L 4AU3B 1IZ2A 1F0CA 1AZXI 2H4PA 4AJTA 2XN6A 4ROBA 1JRRA 1B3KA 1WZ9A 3LW2A 2HIJL 1C5GA 2OL2A 1OYHL 1XQGA 3NDFA 1OVAA 3T1PA 1SR5A 4AFXA 1T1FA 4ROAA 1AS4A 3DY0A 2WXZC 2DUTA 1DZHL 3NDAA 2V95A 2ZNHA 4PYWA 1SNGA 2WXXA 2WXYC 1JVQI 5BRRI 2PEFA 4DTEA 4CAAA 4AU3A 2HI9A 2WY0C 1NQ9I 1E04I 4G8RA 4P0FA 4ZK0A 3OZQA 1XU8A 1LQ8A 1E03I 1SEKA
chains in the Genus database with same CATH topology
2ZV6A 3NDDA 5CDZA 1ANTI 9APIA 1JMOA 2BEHI 3Q02A 2RIWA 2B4XI 3DRUA 3R4LA 4RSQA 3F1SA 4R9IA 2XN3A 1C8OA 1QLPA 5EI0A 1E05I 2ANTI 4X30A 1HLEA 1TB6I 2H4QA 3F02A 2R9YA 2RIVA 3NE4A 1OVAC 2VDYA 1QMNA 4AJUA 3LE2A 2CEOA 1DVNA 4AU2A 4C49A 9PAIA 1M93B 4IF8A 3UT3A 3FGQA 1XQJA 1HP7A 3Q03A 1ATUA 4Y40A 1PSIA 1YXAA 1LJ5A 3CAAA 4AU4A 2H4RA 1OO8A 1DZGI 4DY0A 1JTIA 1QMBA 4EB1I 4YIAA 4BB2A 3B9FI 1D5SA 2VDXA 2ARQA 3CVMA 4G8OA 3F5NA 2HIJI 2ARRA 2VH4A 5CE0A 8APIA 3DLWA 1OYHI 2BEHL 4IC0A 4C41A 3KCGI 4Y3KA 2B5TI 1UHGA 2ACHA 5C98A 1JMJA 2B4XL 2QUGA 1R1LI 1DZHI 1ATHA 3PB1I 4ZK3A 4AQHA 1JJOC 1OC0A 2WXZA 1OPHA 3STOA 1EZXA 1LK6I 1DB2A 3DRMA 3ZHAA 2WXWA 2GD4C 4KDSA 4P0OA 1IMVA 2D26A 1BY7A 7APIA 2XN7A 1A7CA 3CWLA 2OAYA 2PEEA 3H5CA 1KCTA 1DVMA 5IO1A 1BR8I 3EOXA 5HGCA 1OVAB 4RO9A 3EVJI 4GA7A 2WY1A 3CWMA 4DY7C 1K9OI 1ATTA 2XN5A 3VVJA 5INWA 5CDXA 1DZGL 3PZFA 1MTPA 4EB1L 4AU3B 1IZ2A 1F0CA 1AZXI 2H4PA 4AJTA 2XN6A 4ROBA 1JRRA 1B3KA 1WZ9A 3LW2A 2HIJL 1C5GA 2OL2A 1OYHL 1XQGA 3NDFA 1OVAA 3T1PA 1SR5A 4AFXA 1T1FA 4ROAA 1AS4A 3DY0A 2WXZC 2DUTA 1DZHL 3NDAA 2V95A 2ZNHA 4PYWA 1SNGA 2WXXA 2WXYC 1JVQI 5BRRI 2PEFA 4DTEA 4CAAA 4AU3A 2HI9A 2WY0C 1NQ9I 1E04I 4G8RA 4P0FA 4ZK0A 3OZQA 1XU8A 1LQ8A 1E03I 1SEKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZV6 A;  3NDD A;  5CDZ A;  1ANT I;  9API A;  1JMO A;  2BEH I;  3Q02 A;  2RIW A;  2B4X I;  3DRU A;  3R4L A;  4RSQ A;  3F1S A;  4R9I A;  2XN3 A;  1C8O A;  1QLP A;  5EI0 A;  1E05 I;  2ANT I;  4X30 A;  1HLE A;  1TB6 I;  2H4Q A;  3F02 A;  2R9Y A;  2RIV A;  3NE4 A;  1OVA C;  2VDY A;  1QMN A;  4AJU A;  3LE2 A;  2CEO A;  1DVN A;  4AU2 A;  4C49 A;  9PAI A;  1M93 B;  4IF8 A;  3UT3 A;  3FGQ A;  1XQJ A;  1HP7 A;  3Q03 A;  1ATU A;  4Y40 A;  1PSI A;  1YXA A;  1LJ5 A;  3CAA A;  4AU4 A;  2H4R A;  1OO8 A;  1DZG I;  4DY0 A;  1JTI A;  1QMB A;  4EB1 I;  4YIA A;  4BB2 A;  3B9F I;  1D5S A;  2VDX A;  2ARQ A;  3CVM A;  4G8O A;  3F5N A;  2HIJ I;  2ARR A;  2VH4 A;  5CE0 A;  8API A;  3DLW A;  1OYH I;  2BEH L;  4IC0 A;  4C41 A;  3KCG I;  4Y3K A;  2B5T I;  1UHG A;  2ACH A;  5C98 A;  1JMJ A;  2B4X L;  2QUG A;  1R1L I;  1DZH I;  1ATH A;  3PB1 I;  4ZK3 A;  4AQH A;  1JJO C;  1OC0 A;  2WXZ A;  1OPH A;  3STO A;  1EZX A;  1LK6 I;  1DB2 A;  3DRM A;  3ZHA A;  2WXW A;  2GD4 C;  4KDS A;  4P0O A;  1IMV A;  2D26 A;  1BY7 A;  7API A;  2XN7 A;  1A7C A;  3CWL A;  2OAY A;  2PEE A;  3H5C A;  1KCT A;  1DVM A;  5IO1 A;  1BR8 I;  3EOX A;  5HGC A;  1OVA B;  4RO9 A;  3EVJ I;  4GA7 A;  2WY1 A;  3CWM A;  4DY7 C;  1K9O I;  1ATT A;  2XN5 A;  3VVJ A;  5INW A;  5CDX A;  1DZG L;  3PZF A;  1MTP A;  4EB1 L;  4AU3 B;  1IZ2 A;  1F0C A;  1AZX I;  2H4P A;  4AJT A;  2XN6 A;  4ROB A;  1JRR A;  1B3K A;  1WZ9 A;  3LW2 A;  2HIJ L;  1C5G A;  2OL2 A;  1OYH L;  1XQG A;  3NDF A;  1OVA A;  3T1P A;  1SR5 A;  4AFX A;  1T1F A;  4ROA A;  1AS4 A;  3DY0 A;  2WXZ C;  2DUT A;  1DZH L;  3NDA A;  2V95 A;  2ZNH A;  4PYW A;  1SNG A;  2WXX A;  2WXY C;  1JVQ I;  5BRR I;  2PEF A;  4DTE A;  4CAA A;  4AU3 A;  2HI9 A;  2WY0 C;  1NQ9 I;  1E04 I;  4G8R A;  4P0F A;  4ZK0 A;  3OZQ A;  1XU8 A;  1LQ8 A;  1E03 I;  1SEK A; 
#chains in the Genus database with same CATH topology
 2ZV6 A;  3NDD A;  5CDZ A;  1ANT I;  9API A;  1JMO A;  2BEH I;  3Q02 A;  2RIW A;  2B4X I;  3DRU A;  3R4L A;  4RSQ A;  3F1S A;  4R9I A;  2XN3 A;  1C8O A;  1QLP A;  5EI0 A;  1E05 I;  2ANT I;  4X30 A;  1HLE A;  1TB6 I;  2H4Q A;  3F02 A;  2R9Y A;  2RIV A;  3NE4 A;  1OVA C;  2VDY A;  1QMN A;  4AJU A;  3LE2 A;  2CEO A;  1DVN A;  4AU2 A;  4C49 A;  9PAI A;  1M93 B;  4IF8 A;  3UT3 A;  3FGQ A;  1XQJ A;  1HP7 A;  3Q03 A;  1ATU A;  4Y40 A;  1PSI A;  1YXA A;  1LJ5 A;  3CAA A;  4AU4 A;  2H4R A;  1OO8 A;  1DZG I;  4DY0 A;  1JTI A;  1QMB A;  4EB1 I;  4YIA A;  4BB2 A;  3B9F I;  1D5S A;  2VDX A;  2ARQ A;  3CVM A;  4G8O A;  3F5N A;  2HIJ I;  2ARR A;  2VH4 A;  5CE0 A;  8API A;  3DLW A;  1OYH I;  2BEH L;  4IC0 A;  4C41 A;  3KCG I;  4Y3K A;  2B5T I;  1UHG A;  2ACH A;  5C98 A;  1JMJ A;  2B4X L;  2QUG A;  1R1L I;  1DZH I;  1ATH A;  3PB1 I;  4ZK3 A;  4AQH A;  1JJO C;  1OC0 A;  2WXZ A;  1OPH A;  3STO A;  1EZX A;  1LK6 I;  1DB2 A;  3DRM A;  3ZHA A;  2WXW A;  2GD4 C;  4KDS A;  4P0O A;  1IMV A;  2D26 A;  1BY7 A;  7API A;  2XN7 A;  1A7C A;  3CWL A;  2OAY A;  2PEE A;  3H5C A;  1KCT A;  1DVM A;  5IO1 A;  1BR8 I;  3EOX A;  5HGC A;  1OVA B;  4RO9 A;  3EVJ I;  4GA7 A;  2WY1 A;  3CWM A;  4DY7 C;  1K9O I;  1ATT A;  2XN5 A;  3VVJ A;  5INW A;  5CDX A;  1DZG L;  3PZF A;  1MTP A;  4EB1 L;  4AU3 B;  1IZ2 A;  1F0C A;  1AZX I;  2H4P A;  4AJT A;  2XN6 A;  4ROB A;  1JRR A;  1B3K A;  1WZ9 A;  3LW2 A;  2HIJ L;  1C5G A;  2OL2 A;  1OYH L;  1XQG A;  3NDF A;  1OVA A;  3T1P A;  1SR5 A;  4AFX A;  1T1F A;  4ROA A;  1AS4 A;  3DY0 A;  2WXZ C;  2DUT A;  1DZH L;  3NDA A;  2V95 A;  2ZNH A;  4PYW A;  1SNG A;  2WXX A;  2WXY C;  1JVQ I;  5BRR I;  2PEF A;  4DTE A;  4CAA A;  4AU3 A;  2HI9 A;  2WY0 C;  1NQ9 I;  1E04 I;  4G8R A;  4P0F A;  4ZK0 A;  3OZQ A;  1XU8 A;  1LQ8 A;  1E03 I;  1SEK A; 
#chains in the Genus database with same CATH homology
 2ZV6 A;  3NDD A;  5CDZ A;  1ANT I;  9API A;  1JMO A;  2BEH I;  3Q02 A;  2RIW A;  2B4X I;  3DRU A;  3R4L A;  4RSQ A;  3F1S A;  4R9I A;  2XN3 A;  1C8O A;  1QLP A;  5EI0 A;  1E05 I;  2ANT I;  4X30 A;  1HLE A;  1TB6 I;  2H4Q A;  3F02 A;  2R9Y A;  2RIV A;  3NE4 A;  1OVA C;  2VDY A;  1QMN A;  4AJU A;  3LE2 A;  2CEO A;  1DVN A;  4AU2 A;  4C49 A;  9PAI A;  1M93 B;  4IF8 A;  3UT3 A;  3FGQ A;  1XQJ A;  1HP7 A;  3Q03 A;  1ATU A;  4Y40 A;  1PSI A;  1YXA A;  1LJ5 A;  3CAA A;  4AU4 A;  2H4R A;  1OO8 A;  1DZG I;  4DY0 A;  1JTI A;  1QMB A;  4EB1 I;  4YIA A;  4BB2 A;  3B9F I;  1D5S A;  2VDX A;  2ARQ A;  3CVM A;  4G8O A;  3F5N A;  2HIJ I;  2ARR A;  2VH4 A;  5CE0 A;  8API A;  3DLW A;  1OYH I;  2BEH L;  4IC0 A;  4C41 A;  3KCG I;  4Y3K A;  2B5T I;  1UHG A;  2ACH A;  5C98 A;  1JMJ A;  2B4X L;  2QUG A;  1R1L I;  1DZH I;  1ATH A;  3PB1 I;  4ZK3 A;  4AQH A;  1JJO C;  1OC0 A;  2WXZ A;  1OPH A;  3STO A;  1EZX A;  1LK6 I;  1DB2 A;  3DRM A;  3ZHA A;  2WXW A;  2GD4 C;  4KDS A;  4P0O A;  1IMV A;  2D26 A;  1BY7 A;  7API A;  2XN7 A;  1A7C A;  3CWL A;  2OAY A;  2PEE A;  3H5C A;  1KCT A;  1DVM A;  5IO1 A;  1BR8 I;  3EOX A;  5HGC A;  1OVA B;  4RO9 A;  3EVJ I;  4GA7 A;  2WY1 A;  3CWM A;  4DY7 C;  1K9O I;  1ATT A;  2XN5 A;  3VVJ A;  5INW A;  5CDX A;  1DZG L;  3PZF A;  1MTP A;  4EB1 L;  4AU3 B;  1IZ2 A;  1F0C A;  1AZX I;  2H4P A;  4AJT A;  2XN6 A;  4ROB A;  1JRR A;  1B3K A;  1WZ9 A;  3LW2 A;  2HIJ L;  1C5G A;  2OL2 A;  1OYH L;  1XQG A;  3NDF A;  1OVA A;  3T1P A;  1SR5 A;  4AFX A;  1T1F A;  4ROA A;  1AS4 A;  3DY0 A;  2WXZ C;  2DUT A;  1DZH L;  3NDA A;  2V95 A;  2ZNH A;  4PYW A;  1SNG A;  2WXX A;  2WXY C;  1JVQ I;  5BRR I;  2PEF A;  4DTE A;  4CAA A;  4AU3 A;  2HI9 A;  2WY0 C;  1NQ9 I;  1E04 I;  4G8R A;  4P0F A;  4ZK0 A;  3OZQ A;  1XU8 A;  1LQ8 A;  1E03 I;  1SEK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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