3STOA

Serpin from the trematode schistosoma haematobium
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
388
structure length
370
Chain Sequence
ISSHKAFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLEENVVRISTGIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase inhibitor
molecule keywords Serine protease inhibitor
publication title Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain.
pubmed doi rcsb
source organism Schistosoma haematobium
total genus 113
structure length 370
sequence length 388
ec nomenclature
pdb deposition date 2011-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 3stoA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 3stoA01
3CVMA 1T1FA 3OZQA 1AS4A 2QUGA 2XN3A 3PB1I 1ATTA 4AQHA 2WXWA 9APIA 1LQ8A 1K9OI 4C41A 5CDXA 1DZHI 2WY0C 1E03I 2V95A 1QMNA 1ATHA 3DY0A 4AJTA 1AZXI 3R4LA 3F02A 3STOA 8APIA 4DY0A 1JRRA 2B4XL 3B9FI 3DRMA 2XN6A 1E05I 2ZV6A 1C5GA 1WZ9A 2H4QA 1R1LI 4ROAA 3PZFA 1OYHL 3NDFA 2BEHL 3H5CA 9PAIA 3DLWA 3CWLA 2ZNHA 1LJ5A 3FGQA 2H4PA 2WXXA 5HGCA 3EOXA 2GD4C 2D26A 2WXZA 2PEFA 2WXZC 4EB1L 1JVQI 4IF8A 2OAYA 2CEOA 2B5TI 3EVJI 2B4XI 1HP7A 5EI0A 1JMJA 1XU8A 2PEEA 3LW2A 1OPHA 4AJUA 1OYHI 1EZXA 3Q02A 1ANTI 3T1PA 2BEHI 4P0FA 1HLEA 1DVNA 4RO9A 1IMVA 2WXYC 3KCGI 1B3KA 1OO8A 4R9IA 2VDXA 2ANTI 2VH4A 4Y40A 1A7CA 1QLPA 1XQGA 3F5NA 4EB1I 4GA7A 2ARQA 4AFXA 3NE4A 1E04I 4G8OA 4P0OA 1OC0A 4X30A 2HIJL 4AU4A 3NDDA 2H4RA 5INWA 5IO1A 1DZGL 1IZ2A 3ZHAA 4C49A 1DB2A 1OVAB 3LE2A 4CAAA 1JMOA 2XN5A 4AU3B 3CAAA 1C8OA 1QMBA 2HI9A 2OL2A 2WY1A 1DVMA 1TB6I 3DRUA 4ZK3A 3F1SA 4PYWA 7APIA 1PSIA 3VVJA 1BY7A 1KCTA 1M93B 2XN7A 4YIAA 1D5SA 4ZK0A 4G8RA 1SR5A 1OVAA 4IC0A 4RSQA 1OVAC 2HIJI 4Y3KA 4AU2A 1SNGA 4AU3A 1YXAA 2RIVA 1DZGI 5CE0A 1NQ9I 5CDZA 1SEKA 2DUTA 4ROBA 2R9YA 1BR8I 5BRRI 1F0CA 1ATUA 2ACHA 4KDSA 1MTPA 4DTEA 2ARRA 1DZHL 1UHGA 3UT3A 2RIWA 4BB2A 1JJOC 1XQJA 3CWMA 1JTIA 3NDAA 3Q03A 2VDYA 5C98A 1LK6I 4DY7C
chains in the Genus database with same CATH superfamily
3CVMA 1T1FA 3OZQA 1AS4A 2QUGA 2XN3A 3PB1I 1ATTA 4AQHA 2WXWA 9APIA 1LQ8A 1K9OI 4C41A 5CDXA 1DZHI 2WY0C 1E03I 2V95A 1QMNA 1ATHA 3DY0A 4AJTA 1AZXI 3R4LA 3F02A 3STOA 8APIA 4DY0A 1JRRA 2B4XL 3B9FI 3DRMA 2XN6A 1E05I 2ZV6A 1C5GA 1WZ9A 2H4QA 1R1LI 4ROAA 3PZFA 1OYHL 3NDFA 2BEHL 3H5CA 9PAIA 3DLWA 3CWLA 2ZNHA 1LJ5A 3FGQA 2H4PA 2WXXA 5HGCA 3EOXA 2GD4C 2D26A 2WXZA 2PEFA 2WXZC 4EB1L 1JVQI 4IF8A 2OAYA 2CEOA 2B5TI 3EVJI 2B4XI 1HP7A 5EI0A 1JMJA 1XU8A 2PEEA 3LW2A 1OPHA 4AJUA 1OYHI 1EZXA 3Q02A 1ANTI 3T1PA 2BEHI 4P0FA 1HLEA 1DVNA 4RO9A 1IMVA 2WXYC 3KCGI 1B3KA 1OO8A 4R9IA 2VDXA 2ANTI 2VH4A 4Y40A 1A7CA 1QLPA 1XQGA 3F5NA 4EB1I 4GA7A 2ARQA 4AFXA 3NE4A 1E04I 4G8OA 4P0OA 1OC0A 4X30A 2HIJL 4AU4A 3NDDA 2H4RA 5INWA 5IO1A 1DZGL 1IZ2A 3ZHAA 4C49A 1DB2A 1OVAB 3LE2A 4CAAA 1JMOA 2XN5A 4AU3B 3CAAA 1C8OA 1QMBA 2HI9A 2OL2A 2WY1A 1DVMA 1TB6I 3DRUA 4ZK3A 3F1SA 4PYWA 7APIA 1PSIA 3VVJA 1BY7A 1KCTA 1M93B 2XN7A 4YIAA 1D5SA 4ZK0A 4G8RA 1SR5A 1OVAA 4IC0A 4RSQA 1OVAC 2HIJI 4Y3KA 4AU2A 1SNGA 4AU3A 1YXAA 2RIVA 1DZGI 5CE0A 1NQ9I 5CDZA 1SEKA 2DUTA 4ROBA 2R9YA 1BR8I 5BRRI 1F0CA 1ATUA 2ACHA 4KDSA 1MTPA 4DTEA 2ARRA 1DZHL 1UHGA 3UT3A 2RIWA 4BB2A 1JJOC 1XQJA 3CWMA 1JTIA 3NDAA 3Q03A 2VDYA 5C98A 1LK6I 4DY7C
chains in the Genus database with same CATH topology
3CVMA 1T1FA 3OZQA 1AS4A 2QUGA 2XN3A 3PB1I 1ATTA 4AQHA 2WXWA 9APIA 1LQ8A 1K9OI 4C41A 5CDXA 1DZHI 2WY0C 1E03I 2V95A 1QMNA 1ATHA 3DY0A 4AJTA 1AZXI 3R4LA 3F02A 3STOA 8APIA 4DY0A 1JRRA 2B4XL 3B9FI 3DRMA 2XN6A 1E05I 2ZV6A 1C5GA 1WZ9A 2H4QA 1R1LI 4ROAA 3PZFA 1OYHL 3NDFA 2BEHL 3H5CA 9PAIA 3DLWA 3CWLA 2ZNHA 1LJ5A 3FGQA 2H4PA 2WXXA 5HGCA 3EOXA 2GD4C 2D26A 2WXZA 2PEFA 2WXZC 4EB1L 1JVQI 4IF8A 2OAYA 2CEOA 2B5TI 3EVJI 2B4XI 1HP7A 5EI0A 1JMJA 1XU8A 2PEEA 3LW2A 1OPHA 4AJUA 1OYHI 1EZXA 3Q02A 1ANTI 3T1PA 2BEHI 4P0FA 1HLEA 1DVNA 4RO9A 1IMVA 2WXYC 3KCGI 1B3KA 1OO8A 4R9IA 2VDXA 2ANTI 2VH4A 4Y40A 1A7CA 1QLPA 1XQGA 3F5NA 4EB1I 4GA7A 2ARQA 4AFXA 3NE4A 1E04I 4G8OA 4P0OA 1OC0A 4X30A 2HIJL 4AU4A 3NDDA 2H4RA 5INWA 5IO1A 1DZGL 1IZ2A 3ZHAA 4C49A 1DB2A 1OVAB 3LE2A 4CAAA 1JMOA 2XN5A 4AU3B 3CAAA 1C8OA 1QMBA 2HI9A 2OL2A 2WY1A 1DVMA 1TB6I 3DRUA 4ZK3A 3F1SA 4PYWA 7APIA 1PSIA 3VVJA 1BY7A 1KCTA 1M93B 2XN7A 4YIAA 1D5SA 4ZK0A 4G8RA 1SR5A 1OVAA 4IC0A 4RSQA 1OVAC 2HIJI 4Y3KA 4AU2A 1SNGA 4AU3A 1YXAA 2RIVA 1DZGI 5CE0A 1NQ9I 5CDZA 1SEKA 2DUTA 4ROBA 2R9YA 1BR8I 5BRRI 1F0CA 1ATUA 2ACHA 4KDSA 1MTPA 4DTEA 2ARRA 1DZHL 1UHGA 3UT3A 2RIWA 4BB2A 1JJOC 1XQJA 3CWMA 1JTIA 3NDAA 3Q03A 2VDYA 5C98A 1LK6I 4DY7C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CVM A;  1T1F A;  3OZQ A;  1AS4 A;  2QUG A;  2XN3 A;  3PB1 I;  1ATT A;  4AQH A;  2WXW A;  9API A;  1LQ8 A;  1K9O I;  4C41 A;  5CDX A;  1DZH I;  2WY0 C;  1E03 I;  2V95 A;  1QMN A;  1ATH A;  3DY0 A;  4AJT A;  1AZX I;  3R4L A;  3F02 A;  3STO A;  8API A;  4DY0 A;  1JRR A;  2B4X L;  3B9F I;  3DRM A;  2XN6 A;  1E05 I;  2ZV6 A;  1C5G A;  1WZ9 A;  2H4Q A;  1R1L I;  4ROA A;  3PZF A;  1OYH L;  3NDF A;  2BEH L;  3H5C A;  9PAI A;  3DLW A;  3CWL A;  2ZNH A;  1LJ5 A;  3FGQ A;  2H4P A;  2WXX A;  5HGC A;  3EOX A;  2GD4 C;  2D26 A;  2WXZ A;  2PEF A;  2WXZ C;  4EB1 L;  1JVQ I;  4IF8 A;  2OAY A;  2CEO A;  2B5T I;  3EVJ I;  2B4X I;  1HP7 A;  5EI0 A;  1JMJ A;  1XU8 A;  2PEE A;  3LW2 A;  1OPH A;  4AJU A;  1OYH I;  1EZX A;  3Q02 A;  1ANT I;  3T1P A;  2BEH I;  4P0F A;  1HLE A;  1DVN A;  4RO9 A;  1IMV A;  2WXY C;  3KCG I;  1B3K A;  1OO8 A;  4R9I A;  2VDX A;  2ANT I;  2VH4 A;  4Y40 A;  1A7C A;  1QLP A;  1XQG A;  3F5N A;  4EB1 I;  4GA7 A;  2ARQ A;  4AFX A;  3NE4 A;  1E04 I;  4G8O A;  4P0O A;  1OC0 A;  4X30 A;  2HIJ L;  4AU4 A;  3NDD A;  2H4R A;  5INW A;  5IO1 A;  1DZG L;  1IZ2 A;  3ZHA A;  4C49 A;  1DB2 A;  1OVA B;  3LE2 A;  4CAA A;  1JMO A;  2XN5 A;  4AU3 B;  3CAA A;  1C8O A;  1QMB A;  2HI9 A;  2OL2 A;  2WY1 A;  1DVM A;  1TB6 I;  3DRU A;  4ZK3 A;  3F1S A;  4PYW A;  7API A;  1PSI A;  3VVJ A;  1BY7 A;  1KCT A;  1M93 B;  2XN7 A;  4YIA A;  1D5S A;  4ZK0 A;  4G8R A;  1SR5 A;  1OVA A;  4IC0 A;  4RSQ A;  1OVA C;  2HIJ I;  4Y3K A;  4AU2 A;  1SNG A;  4AU3 A;  1YXA A;  2RIV A;  1DZG I;  5CE0 A;  1NQ9 I;  5CDZ A;  1SEK A;  2DUT A;  4ROB A;  2R9Y A;  1BR8 I;  5BRR I;  1F0C A;  1ATU A;  2ACH A;  4KDS A;  1MTP A;  4DTE A;  2ARR A;  1DZH L;  1UHG A;  3UT3 A;  2RIW A;  4BB2 A;  1JJO C;  1XQJ A;  3CWM A;  1JTI A;  3NDA A;  3Q03 A;  2VDY A;  5C98 A;  1LK6 I;  4DY7 C; 
#chains in the Genus database with same CATH topology
 3CVM A;  1T1F A;  3OZQ A;  1AS4 A;  2QUG A;  2XN3 A;  3PB1 I;  1ATT A;  4AQH A;  2WXW A;  9API A;  1LQ8 A;  1K9O I;  4C41 A;  5CDX A;  1DZH I;  2WY0 C;  1E03 I;  2V95 A;  1QMN A;  1ATH A;  3DY0 A;  4AJT A;  1AZX I;  3R4L A;  3F02 A;  3STO A;  8API A;  4DY0 A;  1JRR A;  2B4X L;  3B9F I;  3DRM A;  2XN6 A;  1E05 I;  2ZV6 A;  1C5G A;  1WZ9 A;  2H4Q A;  1R1L I;  4ROA A;  3PZF A;  1OYH L;  3NDF A;  2BEH L;  3H5C A;  9PAI A;  3DLW A;  3CWL A;  2ZNH A;  1LJ5 A;  3FGQ A;  2H4P A;  2WXX A;  5HGC A;  3EOX A;  2GD4 C;  2D26 A;  2WXZ A;  2PEF A;  2WXZ C;  4EB1 L;  1JVQ I;  4IF8 A;  2OAY A;  2CEO A;  2B5T I;  3EVJ I;  2B4X I;  1HP7 A;  5EI0 A;  1JMJ A;  1XU8 A;  2PEE A;  3LW2 A;  1OPH A;  4AJU A;  1OYH I;  1EZX A;  3Q02 A;  1ANT I;  3T1P A;  2BEH I;  4P0F A;  1HLE A;  1DVN A;  4RO9 A;  1IMV A;  2WXY C;  3KCG I;  1B3K A;  1OO8 A;  4R9I A;  2VDX A;  2ANT I;  2VH4 A;  4Y40 A;  1A7C A;  1QLP A;  1XQG A;  3F5N A;  4EB1 I;  4GA7 A;  2ARQ A;  4AFX A;  3NE4 A;  1E04 I;  4G8O A;  4P0O A;  1OC0 A;  4X30 A;  2HIJ L;  4AU4 A;  3NDD A;  2H4R A;  5INW A;  5IO1 A;  1DZG L;  1IZ2 A;  3ZHA A;  4C49 A;  1DB2 A;  1OVA B;  3LE2 A;  4CAA A;  1JMO A;  2XN5 A;  4AU3 B;  3CAA A;  1C8O A;  1QMB A;  2HI9 A;  2OL2 A;  2WY1 A;  1DVM A;  1TB6 I;  3DRU A;  4ZK3 A;  3F1S A;  4PYW A;  7API A;  1PSI A;  3VVJ A;  1BY7 A;  1KCT A;  1M93 B;  2XN7 A;  4YIA A;  1D5S A;  4ZK0 A;  4G8R A;  1SR5 A;  1OVA A;  4IC0 A;  4RSQ A;  1OVA C;  2HIJ I;  4Y3K A;  4AU2 A;  1SNG A;  4AU3 A;  1YXA A;  2RIV A;  1DZG I;  5CE0 A;  1NQ9 I;  5CDZ A;  1SEK A;  2DUT A;  4ROB A;  2R9Y A;  1BR8 I;  5BRR I;  1F0C A;  1ATU A;  2ACH A;  4KDS A;  1MTP A;  4DTE A;  2ARR A;  1DZH L;  1UHG A;  3UT3 A;  2RIW A;  4BB2 A;  1JJO C;  1XQJ A;  3CWM A;  1JTI A;  3NDA A;  3Q03 A;  2VDY A;  5C98 A;  1LK6 I;  4DY7 C; 
#chains in the Genus database with same CATH homology
 3CVM A;  1T1F A;  3OZQ A;  1AS4 A;  2QUG A;  2XN3 A;  3PB1 I;  1ATT A;  4AQH A;  2WXW A;  9API A;  1LQ8 A;  1K9O I;  4C41 A;  5CDX A;  1DZH I;  2WY0 C;  1E03 I;  2V95 A;  1QMN A;  1ATH A;  3DY0 A;  4AJT A;  1AZX I;  3R4L A;  3F02 A;  3STO A;  8API A;  4DY0 A;  1JRR A;  2B4X L;  3B9F I;  3DRM A;  2XN6 A;  1E05 I;  2ZV6 A;  1C5G A;  1WZ9 A;  2H4Q A;  1R1L I;  4ROA A;  3PZF A;  1OYH L;  3NDF A;  2BEH L;  3H5C A;  9PAI A;  3DLW A;  3CWL A;  2ZNH A;  1LJ5 A;  3FGQ A;  2H4P A;  2WXX A;  5HGC A;  3EOX A;  2GD4 C;  2D26 A;  2WXZ A;  2PEF A;  2WXZ C;  4EB1 L;  1JVQ I;  4IF8 A;  2OAY A;  2CEO A;  2B5T I;  3EVJ I;  2B4X I;  1HP7 A;  5EI0 A;  1JMJ A;  1XU8 A;  2PEE A;  3LW2 A;  1OPH A;  4AJU A;  1OYH I;  1EZX A;  3Q02 A;  1ANT I;  3T1P A;  2BEH I;  4P0F A;  1HLE A;  1DVN A;  4RO9 A;  1IMV A;  2WXY C;  3KCG I;  1B3K A;  1OO8 A;  4R9I A;  2VDX A;  2ANT I;  2VH4 A;  4Y40 A;  1A7C A;  1QLP A;  1XQG A;  3F5N A;  4EB1 I;  4GA7 A;  2ARQ A;  4AFX A;  3NE4 A;  1E04 I;  4G8O A;  4P0O A;  1OC0 A;  4X30 A;  2HIJ L;  4AU4 A;  3NDD A;  2H4R A;  5INW A;  5IO1 A;  1DZG L;  1IZ2 A;  3ZHA A;  4C49 A;  1DB2 A;  1OVA B;  3LE2 A;  4CAA A;  1JMO A;  2XN5 A;  4AU3 B;  3CAA A;  1C8O A;  1QMB A;  2HI9 A;  2OL2 A;  2WY1 A;  1DVM A;  1TB6 I;  3DRU A;  4ZK3 A;  3F1S A;  4PYW A;  7API A;  1PSI A;  3VVJ A;  1BY7 A;  1KCT A;  1M93 B;  2XN7 A;  4YIA A;  1D5S A;  4ZK0 A;  4G8R A;  1SR5 A;  1OVA A;  4IC0 A;  4RSQ A;  1OVA C;  2HIJ I;  4Y3K A;  4AU2 A;  1SNG A;  4AU3 A;  1YXA A;  2RIV A;  1DZG I;  5CE0 A;  1NQ9 I;  5CDZ A;  1SEK A;  2DUT A;  4ROB A;  2R9Y A;  1BR8 I;  5BRR I;  1F0C A;  1ATU A;  2ACH A;  4KDS A;  1MTP A;  4DTE A;  2ARR A;  1DZH L;  1UHG A;  3UT3 A;  2RIW A;  4BB2 A;  1JJO C;  1XQJ A;  3CWM A;  1JTI A;  3NDA A;  3Q03 A;  2VDY A;  5C98 A;  1LK6 I;  4DY7 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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