4BB2A

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
337
structure length
332
Chain Sequence
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
total genus 98
structure length 332
sequence length 337
ec nomenclature
pdb deposition date 2012-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4bb2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4bb2A01
1OVAC 3DRUA 1DVMA 1F0CA 1K9OI 2ZNHA 2XN5A 1EZXA 7APIA 1OO8A 1DZHI 4EB1L 2H4QA 5CE0A 1E04I 1IMVA 9PAIA 3CWLA 2XN3A 1XU8A 4AQHA 2PEEA 1HP7A 1KCTA 1OYHL 2WXWA 3FGQA 2R9YA 8APIA 3LW2A 3T1PA 3Q03A 4GA7A 2VDXA 2ARQA 2H4RA 4P0OA 3CAAA 1LJ5A 3NDDA 4AU2A 1QMBA 1QMNA 4ROAA 1OPHA 2HIJL 3UT3A 1ATHA 2OL2A 1JMOA 2WXZA 1OVAA 3EVJI 2V95A 1E05I 2BEHI 4DY0A 3VVJA 2GD4C 2VH4A 4Y3KA 1DB2A 1LQ8A 4YIAA 1SNGA 2OAYA 4EB1I 3DRMA 1WZ9A 5INWA 3STOA 1OVAB 1DVNA 1C8OA 4P0FA 4RO9A 1D5SA 2PEFA 4AU4A 4C49A 3F02A 2QUGA 4RSQA 4G8RA 4X30A 3KCGI 5HGCA 4AJTA 4ROBA 5C98A 4CAAA 2HIJI 3NDAA 4IF8A 4DTEA 1DZGL 9APIA 5EI0A 1MTPA 5CDXA 2VDYA 2ACHA 3R4LA 1DZHL 2RIVA 1AZXI 4ZK0A 1LK6I 2HI9A 3CVMA 1UHGA 1HLEA 1TB6I 2XN6A 3Q02A 1R1LI 3F1SA 1SR5A 5CDZA 1BY7A 2XN7A 2ZV6A 3F5NA 2WXYC 1XQGA 1OYHI 2B4XL 4BB2A 1XQJA 4Y40A 1IZ2A 4AU3A 3NE4A 3DLWA 4KDSA 1SEKA 3PB1I 3PZFA 3B9FI 4AJUA 2H4PA 5IO1A 1PSIA 1JTIA 2CEOA 1ANTI 1JMJA 1AS4A 2WY0C 2D26A 4DY7C 2WXXA 3EOXA 2WY1A 4IC0A 1JVQI 1YXAA 1BR8I 1OC0A 1E03I 4AU3B 2RIWA 4C41A 3CWMA 4G8OA 1JRRA 4PYWA 4ZK3A 4AFXA 2B5TI 1C5GA 1ATTA 1A7CA 1B3KA 1JJOC 1M93B 2B4XI 2ARRA 5BRRI 1T1FA 3DY0A 2ANTI 3LE2A 3OZQA 2BEHL 1NQ9I 3NDFA 1QLPA 4R9IA 1DZGI 1ATUA 3H5CA 2WXZC 2DUTA 3ZHAA
chains in the Genus database with same CATH superfamily
1OVAC 3DRUA 1DVMA 1F0CA 1K9OI 2ZNHA 2XN5A 1EZXA 7APIA 1OO8A 1DZHI 4EB1L 2H4QA 5CE0A 1E04I 1IMVA 9PAIA 3CWLA 2XN3A 1XU8A 4AQHA 2PEEA 1HP7A 1KCTA 1OYHL 2WXWA 3FGQA 2R9YA 8APIA 3LW2A 3T1PA 3Q03A 4GA7A 2VDXA 2ARQA 2H4RA 4P0OA 3CAAA 1LJ5A 3NDDA 4AU2A 1QMBA 1QMNA 4ROAA 1OPHA 2HIJL 3UT3A 1ATHA 2OL2A 1JMOA 2WXZA 1OVAA 3EVJI 2V95A 1E05I 2BEHI 4DY0A 3VVJA 2GD4C 2VH4A 4Y3KA 1DB2A 1LQ8A 4YIAA 1SNGA 2OAYA 4EB1I 3DRMA 1WZ9A 5INWA 3STOA 1OVAB 1DVNA 1C8OA 4P0FA 4RO9A 1D5SA 2PEFA 4AU4A 4C49A 3F02A 2QUGA 4RSQA 4G8RA 4X30A 3KCGI 5HGCA 4AJTA 4ROBA 5C98A 4CAAA 2HIJI 3NDAA 4IF8A 4DTEA 1DZGL 9APIA 5EI0A 1MTPA 5CDXA 2VDYA 2ACHA 3R4LA 1DZHL 2RIVA 1AZXI 4ZK0A 1LK6I 2HI9A 3CVMA 1UHGA 1HLEA 1TB6I 2XN6A 3Q02A 1R1LI 3F1SA 1SR5A 5CDZA 1BY7A 2XN7A 2ZV6A 3F5NA 2WXYC 1XQGA 1OYHI 2B4XL 4BB2A 1XQJA 4Y40A 1IZ2A 4AU3A 3NE4A 3DLWA 4KDSA 1SEKA 3PB1I 3PZFA 3B9FI 4AJUA 2H4PA 5IO1A 1PSIA 1JTIA 2CEOA 1ANTI 1JMJA 1AS4A 2WY0C 2D26A 4DY7C 2WXXA 3EOXA 2WY1A 4IC0A 1JVQI 1YXAA 1BR8I 1OC0A 1E03I 4AU3B 2RIWA 4C41A 3CWMA 4G8OA 1JRRA 4PYWA 4ZK3A 4AFXA 2B5TI 1C5GA 1ATTA 1A7CA 1B3KA 1JJOC 1M93B 2B4XI 2ARRA 5BRRI 1T1FA 3DY0A 2ANTI 3LE2A 3OZQA 2BEHL 1NQ9I 3NDFA 1QLPA 4R9IA 1DZGI 1ATUA 3H5CA 2WXZC 2DUTA 3ZHAA
chains in the Genus database with same CATH topology
1OVAC 3DRUA 1DVMA 1F0CA 1K9OI 2ZNHA 2XN5A 1EZXA 7APIA 1OO8A 1DZHI 4EB1L 2H4QA 5CE0A 1E04I 1IMVA 9PAIA 3CWLA 2XN3A 1XU8A 4AQHA 2PEEA 1HP7A 1KCTA 1OYHL 2WXWA 3FGQA 2R9YA 8APIA 3LW2A 3T1PA 3Q03A 4GA7A 2VDXA 2ARQA 2H4RA 4P0OA 3CAAA 1LJ5A 3NDDA 4AU2A 1QMBA 1QMNA 4ROAA 1OPHA 2HIJL 3UT3A 1ATHA 2OL2A 1JMOA 2WXZA 1OVAA 3EVJI 2V95A 1E05I 2BEHI 4DY0A 3VVJA 2GD4C 2VH4A 4Y3KA 1DB2A 1LQ8A 4YIAA 1SNGA 2OAYA 4EB1I 3DRMA 1WZ9A 5INWA 3STOA 1OVAB 1DVNA 1C8OA 4P0FA 4RO9A 1D5SA 2PEFA 4AU4A 4C49A 3F02A 2QUGA 4RSQA 4G8RA 4X30A 3KCGI 5HGCA 4AJTA 4ROBA 5C98A 4CAAA 2HIJI 3NDAA 4IF8A 4DTEA 1DZGL 9APIA 5EI0A 1MTPA 5CDXA 2VDYA 2ACHA 3R4LA 1DZHL 2RIVA 1AZXI 4ZK0A 1LK6I 2HI9A 3CVMA 1UHGA 1HLEA 1TB6I 2XN6A 3Q02A 1R1LI 3F1SA 1SR5A 5CDZA 1BY7A 2XN7A 2ZV6A 3F5NA 2WXYC 1XQGA 1OYHI 2B4XL 4BB2A 1XQJA 4Y40A 1IZ2A 4AU3A 3NE4A 3DLWA 4KDSA 1SEKA 3PB1I 3PZFA 3B9FI 4AJUA 2H4PA 5IO1A 1PSIA 1JTIA 2CEOA 1ANTI 1JMJA 1AS4A 2WY0C 2D26A 4DY7C 2WXXA 3EOXA 2WY1A 4IC0A 1JVQI 1YXAA 1BR8I 1OC0A 1E03I 4AU3B 2RIWA 4C41A 3CWMA 4G8OA 1JRRA 4PYWA 4ZK3A 4AFXA 2B5TI 1C5GA 1ATTA 1A7CA 1B3KA 1JJOC 1M93B 2B4XI 2ARRA 5BRRI 1T1FA 3DY0A 2ANTI 3LE2A 3OZQA 2BEHL 1NQ9I 3NDFA 1QLPA 4R9IA 1DZGI 1ATUA 3H5CA 2WXZC 2DUTA 3ZHAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OVA C;  3DRU A;  1DVM A;  1F0C A;  1K9O I;  2ZNH A;  2XN5 A;  1EZX A;  7API A;  1OO8 A;  1DZH I;  4EB1 L;  2H4Q A;  5CE0 A;  1E04 I;  1IMV A;  9PAI A;  3CWL A;  2XN3 A;  1XU8 A;  4AQH A;  2PEE A;  1HP7 A;  1KCT A;  1OYH L;  2WXW A;  3FGQ A;  2R9Y A;  8API A;  3LW2 A;  3T1P A;  3Q03 A;  4GA7 A;  2VDX A;  2ARQ A;  2H4R A;  4P0O A;  3CAA A;  1LJ5 A;  3NDD A;  4AU2 A;  1QMB A;  1QMN A;  4ROA A;  1OPH A;  2HIJ L;  3UT3 A;  1ATH A;  2OL2 A;  1JMO A;  2WXZ A;  1OVA A;  3EVJ I;  2V95 A;  1E05 I;  2BEH I;  4DY0 A;  3VVJ A;  2GD4 C;  2VH4 A;  4Y3K A;  1DB2 A;  1LQ8 A;  4YIA A;  1SNG A;  2OAY A;  4EB1 I;  3DRM A;  1WZ9 A;  5INW A;  3STO A;  1OVA B;  1DVN A;  1C8O A;  4P0F A;  4RO9 A;  1D5S A;  2PEF A;  4AU4 A;  4C49 A;  3F02 A;  2QUG A;  4RSQ A;  4G8R A;  4X30 A;  3KCG I;  5HGC A;  4AJT A;  4ROB A;  5C98 A;  4CAA A;  2HIJ I;  3NDA A;  4IF8 A;  4DTE A;  1DZG L;  9API A;  5EI0 A;  1MTP A;  5CDX A;  2VDY A;  2ACH A;  3R4L A;  1DZH L;  2RIV A;  1AZX I;  4ZK0 A;  1LK6 I;  2HI9 A;  3CVM A;  1UHG A;  1HLE A;  1TB6 I;  2XN6 A;  3Q02 A;  1R1L I;  3F1S A;  1SR5 A;  5CDZ A;  1BY7 A;  2XN7 A;  2ZV6 A;  3F5N A;  2WXY C;  1XQG A;  1OYH I;  2B4X L;  4BB2 A;  1XQJ A;  4Y40 A;  1IZ2 A;  4AU3 A;  3NE4 A;  3DLW A;  4KDS A;  1SEK A;  3PB1 I;  3PZF A;  3B9F I;  4AJU A;  2H4P A;  5IO1 A;  1PSI A;  1JTI A;  2CEO A;  1ANT I;  1JMJ A;  1AS4 A;  2WY0 C;  2D26 A;  4DY7 C;  2WXX A;  3EOX A;  2WY1 A;  4IC0 A;  1JVQ I;  1YXA A;  1BR8 I;  1OC0 A;  1E03 I;  4AU3 B;  2RIW A;  4C41 A;  3CWM A;  4G8O A;  1JRR A;  4PYW A;  4ZK3 A;  4AFX A;  2B5T I;  1C5G A;  1ATT A;  1A7C A;  1B3K A;  1JJO C;  1M93 B;  2B4X I;  2ARR A;  5BRR I;  1T1F A;  3DY0 A;  2ANT I;  3LE2 A;  3OZQ A;  2BEH L;  1NQ9 I;  3NDF A;  1QLP A;  4R9I A;  1DZG I;  1ATU A;  3H5C A;  2WXZ C;  2DUT A;  3ZHA A; 
#chains in the Genus database with same CATH topology
 1OVA C;  3DRU A;  1DVM A;  1F0C A;  1K9O I;  2ZNH A;  2XN5 A;  1EZX A;  7API A;  1OO8 A;  1DZH I;  4EB1 L;  2H4Q A;  5CE0 A;  1E04 I;  1IMV A;  9PAI A;  3CWL A;  2XN3 A;  1XU8 A;  4AQH A;  2PEE A;  1HP7 A;  1KCT A;  1OYH L;  2WXW A;  3FGQ A;  2R9Y A;  8API A;  3LW2 A;  3T1P A;  3Q03 A;  4GA7 A;  2VDX A;  2ARQ A;  2H4R A;  4P0O A;  3CAA A;  1LJ5 A;  3NDD A;  4AU2 A;  1QMB A;  1QMN A;  4ROA A;  1OPH A;  2HIJ L;  3UT3 A;  1ATH A;  2OL2 A;  1JMO A;  2WXZ A;  1OVA A;  3EVJ I;  2V95 A;  1E05 I;  2BEH I;  4DY0 A;  3VVJ A;  2GD4 C;  2VH4 A;  4Y3K A;  1DB2 A;  1LQ8 A;  4YIA A;  1SNG A;  2OAY A;  4EB1 I;  3DRM A;  1WZ9 A;  5INW A;  3STO A;  1OVA B;  1DVN A;  1C8O A;  4P0F A;  4RO9 A;  1D5S A;  2PEF A;  4AU4 A;  4C49 A;  3F02 A;  2QUG A;  4RSQ A;  4G8R A;  4X30 A;  3KCG I;  5HGC A;  4AJT A;  4ROB A;  5C98 A;  4CAA A;  2HIJ I;  3NDA A;  4IF8 A;  4DTE A;  1DZG L;  9API A;  5EI0 A;  1MTP A;  5CDX A;  2VDY A;  2ACH A;  3R4L A;  1DZH L;  2RIV A;  1AZX I;  4ZK0 A;  1LK6 I;  2HI9 A;  3CVM A;  1UHG A;  1HLE A;  1TB6 I;  2XN6 A;  3Q02 A;  1R1L I;  3F1S A;  1SR5 A;  5CDZ A;  1BY7 A;  2XN7 A;  2ZV6 A;  3F5N A;  2WXY C;  1XQG A;  1OYH I;  2B4X L;  4BB2 A;  1XQJ A;  4Y40 A;  1IZ2 A;  4AU3 A;  3NE4 A;  3DLW A;  4KDS A;  1SEK A;  3PB1 I;  3PZF A;  3B9F I;  4AJU A;  2H4P A;  5IO1 A;  1PSI A;  1JTI A;  2CEO A;  1ANT I;  1JMJ A;  1AS4 A;  2WY0 C;  2D26 A;  4DY7 C;  2WXX A;  3EOX A;  2WY1 A;  4IC0 A;  1JVQ I;  1YXA A;  1BR8 I;  1OC0 A;  1E03 I;  4AU3 B;  2RIW A;  4C41 A;  3CWM A;  4G8O A;  1JRR A;  4PYW A;  4ZK3 A;  4AFX A;  2B5T I;  1C5G A;  1ATT A;  1A7C A;  1B3K A;  1JJO C;  1M93 B;  2B4X I;  2ARR A;  5BRR I;  1T1F A;  3DY0 A;  2ANT I;  3LE2 A;  3OZQ A;  2BEH L;  1NQ9 I;  3NDF A;  1QLP A;  4R9I A;  1DZG I;  1ATU A;  3H5C A;  2WXZ C;  2DUT A;  3ZHA A; 
#chains in the Genus database with same CATH homology
 1OVA C;  3DRU A;  1DVM A;  1F0C A;  1K9O I;  2ZNH A;  2XN5 A;  1EZX A;  7API A;  1OO8 A;  1DZH I;  4EB1 L;  2H4Q A;  5CE0 A;  1E04 I;  1IMV A;  9PAI A;  3CWL A;  2XN3 A;  1XU8 A;  4AQH A;  2PEE A;  1HP7 A;  1KCT A;  1OYH L;  2WXW A;  3FGQ A;  2R9Y A;  8API A;  3LW2 A;  3T1P A;  3Q03 A;  4GA7 A;  2VDX A;  2ARQ A;  2H4R A;  4P0O A;  3CAA A;  1LJ5 A;  3NDD A;  4AU2 A;  1QMB A;  1QMN A;  4ROA A;  1OPH A;  2HIJ L;  3UT3 A;  1ATH A;  2OL2 A;  1JMO A;  2WXZ A;  1OVA A;  3EVJ I;  2V95 A;  1E05 I;  2BEH I;  4DY0 A;  3VVJ A;  2GD4 C;  2VH4 A;  4Y3K A;  1DB2 A;  1LQ8 A;  4YIA A;  1SNG A;  2OAY A;  4EB1 I;  3DRM A;  1WZ9 A;  5INW A;  3STO A;  1OVA B;  1DVN A;  1C8O A;  4P0F A;  4RO9 A;  1D5S A;  2PEF A;  4AU4 A;  4C49 A;  3F02 A;  2QUG A;  4RSQ A;  4G8R A;  4X30 A;  3KCG I;  5HGC A;  4AJT A;  4ROB A;  5C98 A;  4CAA A;  2HIJ I;  3NDA A;  4IF8 A;  4DTE A;  1DZG L;  9API A;  5EI0 A;  1MTP A;  5CDX A;  2VDY A;  2ACH A;  3R4L A;  1DZH L;  2RIV A;  1AZX I;  4ZK0 A;  1LK6 I;  2HI9 A;  3CVM A;  1UHG A;  1HLE A;  1TB6 I;  2XN6 A;  3Q02 A;  1R1L I;  3F1S A;  1SR5 A;  5CDZ A;  1BY7 A;  2XN7 A;  2ZV6 A;  3F5N A;  2WXY C;  1XQG A;  1OYH I;  2B4X L;  4BB2 A;  1XQJ A;  4Y40 A;  1IZ2 A;  4AU3 A;  3NE4 A;  3DLW A;  4KDS A;  1SEK A;  3PB1 I;  3PZF A;  3B9F I;  4AJU A;  2H4P A;  5IO1 A;  1PSI A;  1JTI A;  2CEO A;  1ANT I;  1JMJ A;  1AS4 A;  2WY0 C;  2D26 A;  4DY7 C;  2WXX A;  3EOX A;  2WY1 A;  4IC0 A;  1JVQ I;  1YXA A;  1BR8 I;  1OC0 A;  1E03 I;  4AU3 B;  2RIW A;  4C41 A;  3CWM A;  4G8O A;  1JRR A;  4PYW A;  4ZK3 A;  4AFX A;  2B5T I;  1C5G A;  1ATT A;  1A7C A;  1B3K A;  1JJO C;  1M93 B;  2B4X I;  2ARR A;  5BRR I;  1T1F A;  3DY0 A;  2ANT I;  3LE2 A;  3OZQ A;  2BEH L;  1NQ9 I;  3NDF A;  1QLP A;  4R9I A;  1DZG I;  1ATU A;  3H5C A;  2WXZ C;  2DUT A;  3ZHA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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