4BB2A

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
337
structure length
332
Chain Sequence
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
total genus 98
structure length 332
sequence length 337
ec nomenclature
pdb deposition date 2012-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4bb2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4bb2A01
1E04I 4AQHA 1AZXI 1DB2A 1KCTA 4ZK3A 1WZ9A 1TB6I 5HGCA 1AS4A 3DLWA 3NE4A 1OVAA 4AJUA 2ACHA 4G8RA 3CVMA 2H4RA 2WY0C 2VDXA 4ZK0A 2OAYA 5CDZA 2WY1A 2RIVA 3UT3A 3NDFA 1ANTI 2B4XI 5C98A 1E03I 1NQ9I 1T1FA 2V95A 1C5GA 3NDDA 1YXAA 3OZQA 8APIA 3KCGI 1SEKA 1XU8A 3VVJA 4AU3B 2DUTA 2ZNHA 3CWMA 2B4XL 4BB2A 1SR5A 4CAAA 9APIA 2PEFA 2WXYC 1EZXA 2XN5A 1HLEA 1QMNA 2D26A 1QLPA 3CWLA 1PSIA 2H4PA 4AU3A 1LQ8A 3T1PA 2RIWA 1JMJA 4Y40A 3FGQA 1DZGL 1BY7A 1DVMA 1JVQI 2XN7A 3F1SA 3LE2A 2H4QA 4AU2A 2HIJI 4P0OA 5CDXA 2QUGA 2WXZA 5IO1A 1DVNA 1QMBA 4P0FA 4AFXA 3CAAA 4DY0A 4G8OA 3LW2A 2HIJL 1M93B 2OL2A 1DZGI 4R9IA 1IZ2A 2ARRA 4GA7A 1IMVA 1OYHL 2XN6A 3H5CA 3F5NA 2WXWA 1JTIA 3Q03A 3R4LA 1C8OA 1XQGA 1F0CA 1SNGA 3DY0A 1LK6I 4C49A 1B3KA 1JMOA 1HP7A 4RSQA 3ZHAA 4EB1L 1OVAC 3EOXA 4X30A 4PYWA 2ARQA 5INWA 1ATUA 3F02A 1MTPA 1OPHA 3B9FI 1JJOC 3Q02A 5CE0A 2BEHI 9PAIA 1ATHA 1UHGA 1OYHI 2PEEA 3DRUA 1JRRA 2WXZC 1ATTA 2VH4A 1R1LI 2HI9A 2GD4C 4EB1I 2VDYA 1BR8I 1LJ5A 2BEHL 5EI0A 4C41A 1DZHL 4ROBA 1D5SA 4Y3KA 2CEOA 3PZFA 4DY7C 2R9YA 4YIAA 1XQJA 4AU4A 7APIA 3DRMA 1OO8A 2ZV6A 4KDSA 1A7CA 1E05I 4ROAA 4IC0A 4AJTA 2WXXA 1OC0A 1K9OI 3EVJI 1DZHI 2B5TI 4RO9A 3PB1I 3NDAA 3STOA 2ANTI 1OVAB 4DTEA 5BRRI 2XN3A 4IF8A
chains in the Genus database with same CATH superfamily
1E04I 4AQHA 1AZXI 1DB2A 1KCTA 4ZK3A 1WZ9A 1TB6I 5HGCA 1AS4A 3DLWA 3NE4A 1OVAA 4AJUA 2ACHA 4G8RA 3CVMA 2H4RA 2WY0C 2VDXA 4ZK0A 2OAYA 5CDZA 2WY1A 2RIVA 3UT3A 3NDFA 1ANTI 2B4XI 5C98A 1E03I 1NQ9I 1T1FA 2V95A 1C5GA 3NDDA 1YXAA 3OZQA 8APIA 3KCGI 1SEKA 1XU8A 3VVJA 4AU3B 2DUTA 2ZNHA 3CWMA 2B4XL 4BB2A 1SR5A 4CAAA 9APIA 2PEFA 2WXYC 1EZXA 2XN5A 1HLEA 1QMNA 2D26A 1QLPA 3CWLA 1PSIA 2H4PA 4AU3A 1LQ8A 3T1PA 2RIWA 1JMJA 4Y40A 3FGQA 1DZGL 1BY7A 1DVMA 1JVQI 2XN7A 3F1SA 3LE2A 2H4QA 4AU2A 2HIJI 4P0OA 5CDXA 2QUGA 2WXZA 5IO1A 1DVNA 1QMBA 4P0FA 4AFXA 3CAAA 4DY0A 4G8OA 3LW2A 2HIJL 1M93B 2OL2A 1DZGI 4R9IA 1IZ2A 2ARRA 4GA7A 1IMVA 1OYHL 2XN6A 3H5CA 3F5NA 2WXWA 1JTIA 3Q03A 3R4LA 1C8OA 1XQGA 1F0CA 1SNGA 3DY0A 1LK6I 4C49A 1B3KA 1JMOA 1HP7A 4RSQA 3ZHAA 4EB1L 1OVAC 3EOXA 4X30A 4PYWA 2ARQA 5INWA 1ATUA 3F02A 1MTPA 1OPHA 3B9FI 1JJOC 3Q02A 5CE0A 2BEHI 9PAIA 1ATHA 1UHGA 1OYHI 2PEEA 3DRUA 1JRRA 2WXZC 1ATTA 2VH4A 1R1LI 2HI9A 2GD4C 4EB1I 2VDYA 1BR8I 1LJ5A 2BEHL 5EI0A 4C41A 1DZHL 4ROBA 1D5SA 4Y3KA 2CEOA 3PZFA 4DY7C 2R9YA 4YIAA 1XQJA 4AU4A 7APIA 3DRMA 1OO8A 2ZV6A 4KDSA 1A7CA 1E05I 4ROAA 4IC0A 4AJTA 2WXXA 1OC0A 1K9OI 3EVJI 1DZHI 2B5TI 4RO9A 3PB1I 3NDAA 3STOA 2ANTI 1OVAB 4DTEA 5BRRI 2XN3A 4IF8A
chains in the Genus database with same CATH topology
1E04I 4AQHA 1AZXI 1DB2A 1KCTA 4ZK3A 1WZ9A 1TB6I 5HGCA 1AS4A 3DLWA 3NE4A 1OVAA 4AJUA 2ACHA 4G8RA 3CVMA 2H4RA 2WY0C 2VDXA 4ZK0A 2OAYA 5CDZA 2WY1A 2RIVA 3UT3A 3NDFA 1ANTI 2B4XI 5C98A 1E03I 1NQ9I 1T1FA 2V95A 1C5GA 3NDDA 1YXAA 3OZQA 8APIA 3KCGI 1SEKA 1XU8A 3VVJA 4AU3B 2DUTA 2ZNHA 3CWMA 2B4XL 4BB2A 1SR5A 4CAAA 9APIA 2PEFA 2WXYC 1EZXA 2XN5A 1HLEA 1QMNA 2D26A 1QLPA 3CWLA 1PSIA 2H4PA 4AU3A 1LQ8A 3T1PA 2RIWA 1JMJA 4Y40A 3FGQA 1DZGL 1BY7A 1DVMA 1JVQI 2XN7A 3F1SA 3LE2A 2H4QA 4AU2A 2HIJI 4P0OA 5CDXA 2QUGA 2WXZA 5IO1A 1DVNA 1QMBA 4P0FA 4AFXA 3CAAA 4DY0A 4G8OA 3LW2A 2HIJL 1M93B 2OL2A 1DZGI 4R9IA 1IZ2A 2ARRA 4GA7A 1IMVA 1OYHL 2XN6A 3H5CA 3F5NA 2WXWA 1JTIA 3Q03A 3R4LA 1C8OA 1XQGA 1F0CA 1SNGA 3DY0A 1LK6I 4C49A 1B3KA 1JMOA 1HP7A 4RSQA 3ZHAA 4EB1L 1OVAC 3EOXA 4X30A 4PYWA 2ARQA 5INWA 1ATUA 3F02A 1MTPA 1OPHA 3B9FI 1JJOC 3Q02A 5CE0A 2BEHI 9PAIA 1ATHA 1UHGA 1OYHI 2PEEA 3DRUA 1JRRA 2WXZC 1ATTA 2VH4A 1R1LI 2HI9A 2GD4C 4EB1I 2VDYA 1BR8I 1LJ5A 2BEHL 5EI0A 4C41A 1DZHL 4ROBA 1D5SA 4Y3KA 2CEOA 3PZFA 4DY7C 2R9YA 4YIAA 1XQJA 4AU4A 7APIA 3DRMA 1OO8A 2ZV6A 4KDSA 1A7CA 1E05I 4ROAA 4IC0A 4AJTA 2WXXA 1OC0A 1K9OI 3EVJI 1DZHI 2B5TI 4RO9A 3PB1I 3NDAA 3STOA 2ANTI 1OVAB 4DTEA 5BRRI 2XN3A 4IF8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E04 I;  4AQH A;  1AZX I;  1DB2 A;  1KCT A;  4ZK3 A;  1WZ9 A;  1TB6 I;  5HGC A;  1AS4 A;  3DLW A;  3NE4 A;  1OVA A;  4AJU A;  2ACH A;  4G8R A;  3CVM A;  2H4R A;  2WY0 C;  2VDX A;  4ZK0 A;  2OAY A;  5CDZ A;  2WY1 A;  2RIV A;  3UT3 A;  3NDF A;  1ANT I;  2B4X I;  5C98 A;  1E03 I;  1NQ9 I;  1T1F A;  2V95 A;  1C5G A;  3NDD A;  1YXA A;  3OZQ A;  8API A;  3KCG I;  1SEK A;  1XU8 A;  3VVJ A;  4AU3 B;  2DUT A;  2ZNH A;  3CWM A;  2B4X L;  4BB2 A;  1SR5 A;  4CAA A;  9API A;  2PEF A;  2WXY C;  1EZX A;  2XN5 A;  1HLE A;  1QMN A;  2D26 A;  1QLP A;  3CWL A;  1PSI A;  2H4P A;  4AU3 A;  1LQ8 A;  3T1P A;  2RIW A;  1JMJ A;  4Y40 A;  3FGQ A;  1DZG L;  1BY7 A;  1DVM A;  1JVQ I;  2XN7 A;  3F1S A;  3LE2 A;  2H4Q A;  4AU2 A;  2HIJ I;  4P0O A;  5CDX A;  2QUG A;  2WXZ A;  5IO1 A;  1DVN A;  1QMB A;  4P0F A;  4AFX A;  3CAA A;  4DY0 A;  4G8O A;  3LW2 A;  2HIJ L;  1M93 B;  2OL2 A;  1DZG I;  4R9I A;  1IZ2 A;  2ARR A;  4GA7 A;  1IMV A;  1OYH L;  2XN6 A;  3H5C A;  3F5N A;  2WXW A;  1JTI A;  3Q03 A;  3R4L A;  1C8O A;  1XQG A;  1F0C A;  1SNG A;  3DY0 A;  1LK6 I;  4C49 A;  1B3K A;  1JMO A;  1HP7 A;  4RSQ A;  3ZHA A;  4EB1 L;  1OVA C;  3EOX A;  4X30 A;  4PYW A;  2ARQ A;  5INW A;  1ATU A;  3F02 A;  1MTP A;  1OPH A;  3B9F I;  1JJO C;  3Q02 A;  5CE0 A;  2BEH I;  9PAI A;  1ATH A;  1UHG A;  1OYH I;  2PEE A;  3DRU A;  1JRR A;  2WXZ C;  1ATT A;  2VH4 A;  1R1L I;  2HI9 A;  2GD4 C;  4EB1 I;  2VDY A;  1BR8 I;  1LJ5 A;  2BEH L;  5EI0 A;  4C41 A;  1DZH L;  4ROB A;  1D5S A;  4Y3K A;  2CEO A;  3PZF A;  4DY7 C;  2R9Y A;  4YIA A;  1XQJ A;  4AU4 A;  7API A;  3DRM A;  1OO8 A;  2ZV6 A;  4KDS A;  1A7C A;  1E05 I;  4ROA A;  4IC0 A;  4AJT A;  2WXX A;  1OC0 A;  1K9O I;  3EVJ I;  1DZH I;  2B5T I;  4RO9 A;  3PB1 I;  3NDA A;  3STO A;  2ANT I;  1OVA B;  4DTE A;  5BRR I;  2XN3 A;  4IF8 A; 
#chains in the Genus database with same CATH topology
 1E04 I;  4AQH A;  1AZX I;  1DB2 A;  1KCT A;  4ZK3 A;  1WZ9 A;  1TB6 I;  5HGC A;  1AS4 A;  3DLW A;  3NE4 A;  1OVA A;  4AJU A;  2ACH A;  4G8R A;  3CVM A;  2H4R A;  2WY0 C;  2VDX A;  4ZK0 A;  2OAY A;  5CDZ A;  2WY1 A;  2RIV A;  3UT3 A;  3NDF A;  1ANT I;  2B4X I;  5C98 A;  1E03 I;  1NQ9 I;  1T1F A;  2V95 A;  1C5G A;  3NDD A;  1YXA A;  3OZQ A;  8API A;  3KCG I;  1SEK A;  1XU8 A;  3VVJ A;  4AU3 B;  2DUT A;  2ZNH A;  3CWM A;  2B4X L;  4BB2 A;  1SR5 A;  4CAA A;  9API A;  2PEF A;  2WXY C;  1EZX A;  2XN5 A;  1HLE A;  1QMN A;  2D26 A;  1QLP A;  3CWL A;  1PSI A;  2H4P A;  4AU3 A;  1LQ8 A;  3T1P A;  2RIW A;  1JMJ A;  4Y40 A;  3FGQ A;  1DZG L;  1BY7 A;  1DVM A;  1JVQ I;  2XN7 A;  3F1S A;  3LE2 A;  2H4Q A;  4AU2 A;  2HIJ I;  4P0O A;  5CDX A;  2QUG A;  2WXZ A;  5IO1 A;  1DVN A;  1QMB A;  4P0F A;  4AFX A;  3CAA A;  4DY0 A;  4G8O A;  3LW2 A;  2HIJ L;  1M93 B;  2OL2 A;  1DZG I;  4R9I A;  1IZ2 A;  2ARR A;  4GA7 A;  1IMV A;  1OYH L;  2XN6 A;  3H5C A;  3F5N A;  2WXW A;  1JTI A;  3Q03 A;  3R4L A;  1C8O A;  1XQG A;  1F0C A;  1SNG A;  3DY0 A;  1LK6 I;  4C49 A;  1B3K A;  1JMO A;  1HP7 A;  4RSQ A;  3ZHA A;  4EB1 L;  1OVA C;  3EOX A;  4X30 A;  4PYW A;  2ARQ A;  5INW A;  1ATU A;  3F02 A;  1MTP A;  1OPH A;  3B9F I;  1JJO C;  3Q02 A;  5CE0 A;  2BEH I;  9PAI A;  1ATH A;  1UHG A;  1OYH I;  2PEE A;  3DRU A;  1JRR A;  2WXZ C;  1ATT A;  2VH4 A;  1R1L I;  2HI9 A;  2GD4 C;  4EB1 I;  2VDY A;  1BR8 I;  1LJ5 A;  2BEH L;  5EI0 A;  4C41 A;  1DZH L;  4ROB A;  1D5S A;  4Y3K A;  2CEO A;  3PZF A;  4DY7 C;  2R9Y A;  4YIA A;  1XQJ A;  4AU4 A;  7API A;  3DRM A;  1OO8 A;  2ZV6 A;  4KDS A;  1A7C A;  1E05 I;  4ROA A;  4IC0 A;  4AJT A;  2WXX A;  1OC0 A;  1K9O I;  3EVJ I;  1DZH I;  2B5T I;  4RO9 A;  3PB1 I;  3NDA A;  3STO A;  2ANT I;  1OVA B;  4DTE A;  5BRR I;  2XN3 A;  4IF8 A; 
#chains in the Genus database with same CATH homology
 1E04 I;  4AQH A;  1AZX I;  1DB2 A;  1KCT A;  4ZK3 A;  1WZ9 A;  1TB6 I;  5HGC A;  1AS4 A;  3DLW A;  3NE4 A;  1OVA A;  4AJU A;  2ACH A;  4G8R A;  3CVM A;  2H4R A;  2WY0 C;  2VDX A;  4ZK0 A;  2OAY A;  5CDZ A;  2WY1 A;  2RIV A;  3UT3 A;  3NDF A;  1ANT I;  2B4X I;  5C98 A;  1E03 I;  1NQ9 I;  1T1F A;  2V95 A;  1C5G A;  3NDD A;  1YXA A;  3OZQ A;  8API A;  3KCG I;  1SEK A;  1XU8 A;  3VVJ A;  4AU3 B;  2DUT A;  2ZNH A;  3CWM A;  2B4X L;  4BB2 A;  1SR5 A;  4CAA A;  9API A;  2PEF A;  2WXY C;  1EZX A;  2XN5 A;  1HLE A;  1QMN A;  2D26 A;  1QLP A;  3CWL A;  1PSI A;  2H4P A;  4AU3 A;  1LQ8 A;  3T1P A;  2RIW A;  1JMJ A;  4Y40 A;  3FGQ A;  1DZG L;  1BY7 A;  1DVM A;  1JVQ I;  2XN7 A;  3F1S A;  3LE2 A;  2H4Q A;  4AU2 A;  2HIJ I;  4P0O A;  5CDX A;  2QUG A;  2WXZ A;  5IO1 A;  1DVN A;  1QMB A;  4P0F A;  4AFX A;  3CAA A;  4DY0 A;  4G8O A;  3LW2 A;  2HIJ L;  1M93 B;  2OL2 A;  1DZG I;  4R9I A;  1IZ2 A;  2ARR A;  4GA7 A;  1IMV A;  1OYH L;  2XN6 A;  3H5C A;  3F5N A;  2WXW A;  1JTI A;  3Q03 A;  3R4L A;  1C8O A;  1XQG A;  1F0C A;  1SNG A;  3DY0 A;  1LK6 I;  4C49 A;  1B3K A;  1JMO A;  1HP7 A;  4RSQ A;  3ZHA A;  4EB1 L;  1OVA C;  3EOX A;  4X30 A;  4PYW A;  2ARQ A;  5INW A;  1ATU A;  3F02 A;  1MTP A;  1OPH A;  3B9F I;  1JJO C;  3Q02 A;  5CE0 A;  2BEH I;  9PAI A;  1ATH A;  1UHG A;  1OYH I;  2PEE A;  3DRU A;  1JRR A;  2WXZ C;  1ATT A;  2VH4 A;  1R1L I;  2HI9 A;  2GD4 C;  4EB1 I;  2VDY A;  1BR8 I;  1LJ5 A;  2BEH L;  5EI0 A;  4C41 A;  1DZH L;  4ROB A;  1D5S A;  4Y3K A;  2CEO A;  3PZF A;  4DY7 C;  2R9Y A;  4YIA A;  1XQJ A;  4AU4 A;  7API A;  3DRM A;  1OO8 A;  2ZV6 A;  4KDS A;  1A7C A;  1E05 I;  4ROA A;  4IC0 A;  4AJT A;  2WXX A;  1OC0 A;  1K9O I;  3EVJ I;  1DZH I;  2B5T I;  4RO9 A;  3PB1 I;  3NDA A;  3STO A;  2ANT I;  1OVA B;  4DTE A;  5BRR I;  2XN3 A;  4IF8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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