4BB2A

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
337
structure length
332
Chain Sequence
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Homo sapiens
publication title Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
pubmed doi rcsb
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
total genus 98
structure length 332
sequence length 337
ec nomenclature
pdb deposition date 2012-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4bb2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4bb2A01
4AQHA 1M93B 1K9OI 1R1LI 4X30A 3VVJA 1DZHL 1UHGA 8APIA 1OYHL 3F02A 1E04I 3CWMA 2ARRA 1DVNA 2DUTA 1DZHI 3ZHAA 2D26A 3EVJI 1OYHI 2V95A 1F0CA 2B4XL 4ROAA 4R9IA 5BRRI 2PEFA 2OAYA 1AZXI 2WXXA 4AFXA 2GD4C 1OPHA 2B4XI 4GA7A 5HGCA 1LK6I 1HLEA 1OVAC 4AJUA 2XN6A 5CE0A 1OO8A 2CEOA 4P0FA 3NDAA 4YIAA 1B3KA 1DVMA 2QUGA 1QLPA 1LJ5A 3CVMA 1DB2A 3DY0A 1E05I 2XN3A 1JJOC 2BEHL 2ZV6A 1IMVA 4RO9A 1C8OA 1XQGA 2H4QA 2VH4A 1JRRA 2OL2A 2BEHI 2ACHA 4C41A 1E03I 1TB6I 1QMBA 3LE2A 4DTEA 9APIA 1IZ2A 3Q02A 4ZK0A 2ZNHA 1MTPA 4IF8A 2H4PA 3F1SA 4G8OA 1BY7A 2HIJL 3NE4A 1JMJA 3PZFA 3Q03A 2WY0C 1ATUA 4ROBA 4AU3A 1HP7A 3LW2A 2HIJI 4Y3KA 1SR5A 2H4RA 3EOXA 3F5NA 2ARQA 4AU4A 5CDXA 2XN7A 4RSQA 1AS4A 2R9YA 4KDSA 1WZ9A 3UT3A 2WY1A 4P0OA 7APIA 2VDYA 1ANTI 1LQ8A 1OVAA 3DRMA 2WXYC 3DRUA 3CAAA 1JTIA 1KCTA 4EB1L 1OC0A 4C49A 2ANTI 1A7CA 4AJTA 4ZK3A 2WXWA 3FGQA 4G8RA 9PAIA 3NDDA 5INWA 3PB1I 2B5TI 4BB2A 4EB1I 1QMNA 2WXZC 1OVAB 5CDZA 3CWLA 1C5GA 4AU2A 4CAAA 3DLWA 1XQJA 2VDXA 4Y40A 3NDFA 1PSIA 1D5SA 3OZQA 4PYWA 1YXAA 1JMOA 2RIVA 1EZXA 1T1FA 2WXZA 1ATHA 2XN5A 4DY0A 1DZGL 2PEEA 4IC0A 4AU3B 2RIWA 1ATTA 1JVQI 1SNGA 4DY7C 1NQ9I 3KCGI 1DZGI 1SEKA 3T1PA 5IO1A 3R4LA 3H5CA 1BR8I 3STOA 5EI0A 5C98A 1XU8A 3B9FI 2HI9A
chains in the Genus database with same CATH superfamily
4AQHA 1M93B 1K9OI 1R1LI 4X30A 3VVJA 1DZHL 1UHGA 8APIA 1OYHL 3F02A 1E04I 3CWMA 2ARRA 1DVNA 2DUTA 1DZHI 3ZHAA 2D26A 3EVJI 1OYHI 2V95A 1F0CA 2B4XL 4ROAA 4R9IA 5BRRI 2PEFA 2OAYA 1AZXI 2WXXA 4AFXA 2GD4C 1OPHA 2B4XI 4GA7A 5HGCA 1LK6I 1HLEA 1OVAC 4AJUA 2XN6A 5CE0A 1OO8A 2CEOA 4P0FA 3NDAA 4YIAA 1B3KA 1DVMA 2QUGA 1QLPA 1LJ5A 3CVMA 1DB2A 3DY0A 1E05I 2XN3A 1JJOC 2BEHL 2ZV6A 1IMVA 4RO9A 1C8OA 1XQGA 2H4QA 2VH4A 1JRRA 2OL2A 2BEHI 2ACHA 4C41A 1E03I 1TB6I 1QMBA 3LE2A 4DTEA 9APIA 1IZ2A 3Q02A 4ZK0A 2ZNHA 1MTPA 4IF8A 2H4PA 3F1SA 4G8OA 1BY7A 2HIJL 3NE4A 1JMJA 3PZFA 3Q03A 2WY0C 1ATUA 4ROBA 4AU3A 1HP7A 3LW2A 2HIJI 4Y3KA 1SR5A 2H4RA 3EOXA 3F5NA 2ARQA 4AU4A 5CDXA 2XN7A 4RSQA 1AS4A 2R9YA 4KDSA 1WZ9A 3UT3A 2WY1A 4P0OA 7APIA 2VDYA 1ANTI 1LQ8A 1OVAA 3DRMA 2WXYC 3DRUA 3CAAA 1JTIA 1KCTA 4EB1L 1OC0A 4C49A 2ANTI 1A7CA 4AJTA 4ZK3A 2WXWA 3FGQA 4G8RA 9PAIA 3NDDA 5INWA 3PB1I 2B5TI 4BB2A 4EB1I 1QMNA 2WXZC 1OVAB 5CDZA 3CWLA 1C5GA 4AU2A 4CAAA 3DLWA 1XQJA 2VDXA 4Y40A 3NDFA 1PSIA 1D5SA 3OZQA 4PYWA 1YXAA 1JMOA 2RIVA 1EZXA 1T1FA 2WXZA 1ATHA 2XN5A 4DY0A 1DZGL 2PEEA 4IC0A 4AU3B 2RIWA 1ATTA 1JVQI 1SNGA 4DY7C 1NQ9I 3KCGI 1DZGI 1SEKA 3T1PA 5IO1A 3R4LA 3H5CA 1BR8I 3STOA 5EI0A 5C98A 1XU8A 3B9FI 2HI9A
chains in the Genus database with same CATH topology
4AQHA 1M93B 1K9OI 1R1LI 4X30A 3VVJA 1DZHL 1UHGA 8APIA 1OYHL 3F02A 1E04I 3CWMA 2ARRA 1DVNA 2DUTA 1DZHI 3ZHAA 2D26A 3EVJI 1OYHI 2V95A 1F0CA 2B4XL 4ROAA 4R9IA 5BRRI 2PEFA 2OAYA 1AZXI 2WXXA 4AFXA 2GD4C 1OPHA 2B4XI 4GA7A 5HGCA 1LK6I 1HLEA 1OVAC 4AJUA 2XN6A 5CE0A 1OO8A 2CEOA 4P0FA 3NDAA 4YIAA 1B3KA 1DVMA 2QUGA 1QLPA 1LJ5A 3CVMA 1DB2A 3DY0A 1E05I 2XN3A 1JJOC 2BEHL 2ZV6A 1IMVA 4RO9A 1C8OA 1XQGA 2H4QA 2VH4A 1JRRA 2OL2A 2BEHI 2ACHA 4C41A 1E03I 1TB6I 1QMBA 3LE2A 4DTEA 9APIA 1IZ2A 3Q02A 4ZK0A 2ZNHA 1MTPA 4IF8A 2H4PA 3F1SA 4G8OA 1BY7A 2HIJL 3NE4A 1JMJA 3PZFA 3Q03A 2WY0C 1ATUA 4ROBA 4AU3A 1HP7A 3LW2A 2HIJI 4Y3KA 1SR5A 2H4RA 3EOXA 3F5NA 2ARQA 4AU4A 5CDXA 2XN7A 4RSQA 1AS4A 2R9YA 4KDSA 1WZ9A 3UT3A 2WY1A 4P0OA 7APIA 2VDYA 1ANTI 1LQ8A 1OVAA 3DRMA 2WXYC 3DRUA 3CAAA 1JTIA 1KCTA 4EB1L 1OC0A 4C49A 2ANTI 1A7CA 4AJTA 4ZK3A 2WXWA 3FGQA 4G8RA 9PAIA 3NDDA 5INWA 3PB1I 2B5TI 4BB2A 4EB1I 1QMNA 2WXZC 1OVAB 5CDZA 3CWLA 1C5GA 4AU2A 4CAAA 3DLWA 1XQJA 2VDXA 4Y40A 3NDFA 1PSIA 1D5SA 3OZQA 4PYWA 1YXAA 1JMOA 2RIVA 1EZXA 1T1FA 2WXZA 1ATHA 2XN5A 4DY0A 1DZGL 2PEEA 4IC0A 4AU3B 2RIWA 1ATTA 1JVQI 1SNGA 4DY7C 1NQ9I 3KCGI 1DZGI 1SEKA 3T1PA 5IO1A 3R4LA 3H5CA 1BR8I 3STOA 5EI0A 5C98A 1XU8A 3B9FI 2HI9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AQH A;  1M93 B;  1K9O I;  1R1L I;  4X30 A;  3VVJ A;  1DZH L;  1UHG A;  8API A;  1OYH L;  3F02 A;  1E04 I;  3CWM A;  2ARR A;  1DVN A;  2DUT A;  1DZH I;  3ZHA A;  2D26 A;  3EVJ I;  1OYH I;  2V95 A;  1F0C A;  2B4X L;  4ROA A;  4R9I A;  5BRR I;  2PEF A;  2OAY A;  1AZX I;  2WXX A;  4AFX A;  2GD4 C;  1OPH A;  2B4X I;  4GA7 A;  5HGC A;  1LK6 I;  1HLE A;  1OVA C;  4AJU A;  2XN6 A;  5CE0 A;  1OO8 A;  2CEO A;  4P0F A;  3NDA A;  4YIA A;  1B3K A;  1DVM A;  2QUG A;  1QLP A;  1LJ5 A;  3CVM A;  1DB2 A;  3DY0 A;  1E05 I;  2XN3 A;  1JJO C;  2BEH L;  2ZV6 A;  1IMV A;  4RO9 A;  1C8O A;  1XQG A;  2H4Q A;  2VH4 A;  1JRR A;  2OL2 A;  2BEH I;  2ACH A;  4C41 A;  1E03 I;  1TB6 I;  1QMB A;  3LE2 A;  4DTE A;  9API A;  1IZ2 A;  3Q02 A;  4ZK0 A;  2ZNH A;  1MTP A;  4IF8 A;  2H4P A;  3F1S A;  4G8O A;  1BY7 A;  2HIJ L;  3NE4 A;  1JMJ A;  3PZF A;  3Q03 A;  2WY0 C;  1ATU A;  4ROB A;  4AU3 A;  1HP7 A;  3LW2 A;  2HIJ I;  4Y3K A;  1SR5 A;  2H4R A;  3EOX A;  3F5N A;  2ARQ A;  4AU4 A;  5CDX A;  2XN7 A;  4RSQ A;  1AS4 A;  2R9Y A;  4KDS A;  1WZ9 A;  3UT3 A;  2WY1 A;  4P0O A;  7API A;  2VDY A;  1ANT I;  1LQ8 A;  1OVA A;  3DRM A;  2WXY C;  3DRU A;  3CAA A;  1JTI A;  1KCT A;  4EB1 L;  1OC0 A;  4C49 A;  2ANT I;  1A7C A;  4AJT A;  4ZK3 A;  2WXW A;  3FGQ A;  4G8R A;  9PAI A;  3NDD A;  5INW A;  3PB1 I;  2B5T I;  4BB2 A;  4EB1 I;  1QMN A;  2WXZ C;  1OVA B;  5CDZ A;  3CWL A;  1C5G A;  4AU2 A;  4CAA A;  3DLW A;  1XQJ A;  2VDX A;  4Y40 A;  3NDF A;  1PSI A;  1D5S A;  3OZQ A;  4PYW A;  1YXA A;  1JMO A;  2RIV A;  1EZX A;  1T1F A;  2WXZ A;  1ATH A;  2XN5 A;  4DY0 A;  1DZG L;  2PEE A;  4IC0 A;  4AU3 B;  2RIW A;  1ATT A;  1JVQ I;  1SNG A;  4DY7 C;  1NQ9 I;  3KCG I;  1DZG I;  1SEK A;  3T1P A;  5IO1 A;  3R4L A;  3H5C A;  1BR8 I;  3STO A;  5EI0 A;  5C98 A;  1XU8 A;  3B9F I;  2HI9 A; 
#chains in the Genus database with same CATH topology
 4AQH A;  1M93 B;  1K9O I;  1R1L I;  4X30 A;  3VVJ A;  1DZH L;  1UHG A;  8API A;  1OYH L;  3F02 A;  1E04 I;  3CWM A;  2ARR A;  1DVN A;  2DUT A;  1DZH I;  3ZHA A;  2D26 A;  3EVJ I;  1OYH I;  2V95 A;  1F0C A;  2B4X L;  4ROA A;  4R9I A;  5BRR I;  2PEF A;  2OAY A;  1AZX I;  2WXX A;  4AFX A;  2GD4 C;  1OPH A;  2B4X I;  4GA7 A;  5HGC A;  1LK6 I;  1HLE A;  1OVA C;  4AJU A;  2XN6 A;  5CE0 A;  1OO8 A;  2CEO A;  4P0F A;  3NDA A;  4YIA A;  1B3K A;  1DVM A;  2QUG A;  1QLP A;  1LJ5 A;  3CVM A;  1DB2 A;  3DY0 A;  1E05 I;  2XN3 A;  1JJO C;  2BEH L;  2ZV6 A;  1IMV A;  4RO9 A;  1C8O A;  1XQG A;  2H4Q A;  2VH4 A;  1JRR A;  2OL2 A;  2BEH I;  2ACH A;  4C41 A;  1E03 I;  1TB6 I;  1QMB A;  3LE2 A;  4DTE A;  9API A;  1IZ2 A;  3Q02 A;  4ZK0 A;  2ZNH A;  1MTP A;  4IF8 A;  2H4P A;  3F1S A;  4G8O A;  1BY7 A;  2HIJ L;  3NE4 A;  1JMJ A;  3PZF A;  3Q03 A;  2WY0 C;  1ATU A;  4ROB A;  4AU3 A;  1HP7 A;  3LW2 A;  2HIJ I;  4Y3K A;  1SR5 A;  2H4R A;  3EOX A;  3F5N A;  2ARQ A;  4AU4 A;  5CDX A;  2XN7 A;  4RSQ A;  1AS4 A;  2R9Y A;  4KDS A;  1WZ9 A;  3UT3 A;  2WY1 A;  4P0O A;  7API A;  2VDY A;  1ANT I;  1LQ8 A;  1OVA A;  3DRM A;  2WXY C;  3DRU A;  3CAA A;  1JTI A;  1KCT A;  4EB1 L;  1OC0 A;  4C49 A;  2ANT I;  1A7C A;  4AJT A;  4ZK3 A;  2WXW A;  3FGQ A;  4G8R A;  9PAI A;  3NDD A;  5INW A;  3PB1 I;  2B5T I;  4BB2 A;  4EB1 I;  1QMN A;  2WXZ C;  1OVA B;  5CDZ A;  3CWL A;  1C5G A;  4AU2 A;  4CAA A;  3DLW A;  1XQJ A;  2VDX A;  4Y40 A;  3NDF A;  1PSI A;  1D5S A;  3OZQ A;  4PYW A;  1YXA A;  1JMO A;  2RIV A;  1EZX A;  1T1F A;  2WXZ A;  1ATH A;  2XN5 A;  4DY0 A;  1DZG L;  2PEE A;  4IC0 A;  4AU3 B;  2RIW A;  1ATT A;  1JVQ I;  1SNG A;  4DY7 C;  1NQ9 I;  3KCG I;  1DZG I;  1SEK A;  3T1P A;  5IO1 A;  3R4L A;  3H5C A;  1BR8 I;  3STO A;  5EI0 A;  5C98 A;  1XU8 A;  3B9F I;  2HI9 A; 
#chains in the Genus database with same CATH homology
 4AQH A;  1M93 B;  1K9O I;  1R1L I;  4X30 A;  3VVJ A;  1DZH L;  1UHG A;  8API A;  1OYH L;  3F02 A;  1E04 I;  3CWM A;  2ARR A;  1DVN A;  2DUT A;  1DZH I;  3ZHA A;  2D26 A;  3EVJ I;  1OYH I;  2V95 A;  1F0C A;  2B4X L;  4ROA A;  4R9I A;  5BRR I;  2PEF A;  2OAY A;  1AZX I;  2WXX A;  4AFX A;  2GD4 C;  1OPH A;  2B4X I;  4GA7 A;  5HGC A;  1LK6 I;  1HLE A;  1OVA C;  4AJU A;  2XN6 A;  5CE0 A;  1OO8 A;  2CEO A;  4P0F A;  3NDA A;  4YIA A;  1B3K A;  1DVM A;  2QUG A;  1QLP A;  1LJ5 A;  3CVM A;  1DB2 A;  3DY0 A;  1E05 I;  2XN3 A;  1JJO C;  2BEH L;  2ZV6 A;  1IMV A;  4RO9 A;  1C8O A;  1XQG A;  2H4Q A;  2VH4 A;  1JRR A;  2OL2 A;  2BEH I;  2ACH A;  4C41 A;  1E03 I;  1TB6 I;  1QMB A;  3LE2 A;  4DTE A;  9API A;  1IZ2 A;  3Q02 A;  4ZK0 A;  2ZNH A;  1MTP A;  4IF8 A;  2H4P A;  3F1S A;  4G8O A;  1BY7 A;  2HIJ L;  3NE4 A;  1JMJ A;  3PZF A;  3Q03 A;  2WY0 C;  1ATU A;  4ROB A;  4AU3 A;  1HP7 A;  3LW2 A;  2HIJ I;  4Y3K A;  1SR5 A;  2H4R A;  3EOX A;  3F5N A;  2ARQ A;  4AU4 A;  5CDX A;  2XN7 A;  4RSQ A;  1AS4 A;  2R9Y A;  4KDS A;  1WZ9 A;  3UT3 A;  2WY1 A;  4P0O A;  7API A;  2VDY A;  1ANT I;  1LQ8 A;  1OVA A;  3DRM A;  2WXY C;  3DRU A;  3CAA A;  1JTI A;  1KCT A;  4EB1 L;  1OC0 A;  4C49 A;  2ANT I;  1A7C A;  4AJT A;  4ZK3 A;  2WXW A;  3FGQ A;  4G8R A;  9PAI A;  3NDD A;  5INW A;  3PB1 I;  2B5T I;  4BB2 A;  4EB1 I;  1QMN A;  2WXZ C;  1OVA B;  5CDZ A;  3CWL A;  1C5G A;  4AU2 A;  4CAA A;  3DLW A;  1XQJ A;  2VDX A;  4Y40 A;  3NDF A;  1PSI A;  1D5S A;  3OZQ A;  4PYW A;  1YXA A;  1JMO A;  2RIV A;  1EZX A;  1T1F A;  2WXZ A;  1ATH A;  2XN5 A;  4DY0 A;  1DZG L;  2PEE A;  4IC0 A;  4AU3 B;  2RIW A;  1ATT A;  1JVQ I;  1SNG A;  4DY7 C;  1NQ9 I;  3KCG I;  1DZG I;  1SEK A;  3T1P A;  5IO1 A;  3R4L A;  3H5C A;  1BR8 I;  3STO A;  5EI0 A;  5C98 A;  1XU8 A;  3B9F I;  2HI9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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