4F0PA

Mspji restriction endonuclease - p31 form
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
450
structure length
450
Chain Sequence
DIAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium sp.
molecule keywords Restriction endonuclease
total genus 120
structure length 450
sequence length 450
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2012-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04471 Mrr_cat Restriction endonuclease
A PF18062 RE_AspBHI_N Restriction endonuclease AspBHI N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.20 Mainly Beta Roll PUA domain-like PUA domain-like 4f0pA01
3.40.91.100 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 4f0pA02
4RZLA 4R28A 4F0PA 4F0QA 4OC8A
chains in the Genus database with same CATH superfamily
1VRRA 2ZO2B 4R28A 1BAMA 3EBJA 4AWFA 3Q0CA 4NFZA 2P14A 5FDDA 3V20A 3MQ6A 5EGAA 2PFJA 5CGVA 2ZO0B 5JHVA 3MQYA 5I13A 2BAMA 5DBSA 3DPGA 3Q0BX 5CZNA 3WVHA 5D42A 3WVGA 3N78A 4ZI0A 4AWHA 1DC1A 3HW5A 4CHCA 1BHMA 4E5EA 3HW6A 4E5HA 2EWFA 3DW9A 5D4GA 2XI7A 4E5FA 3F8IA 3V1ZA 3HW3A 4RZLA 5DEBA 4YYLA 4NJ5A 2PB7A 2ZKGA 5D9JA 4OC8A 1FOKA 1KNVA 3F8JB 4AWGA 3BM3A 2P0JA 5FDGA 2GB7A 5D2OA 2FQZA 3WVIA 1M0IA 4F0PA 4PW7A 4CGXA 3CAEA 5DESA 3N7BA 3Q0DA 4AVLA 4AVQA 3WVPA 2ZKEA 1ES8A 1CFRA 2ZO1B 4YGIA 4AVGA 1DFMA 5CL0A 5CCYA 3DVOA 4ZQQA 3OLNA 4CGSA 2XI5A 1ESGA 2E52A 4E5GA 4AWKA 2ZKFA 1M0DA 3BI7A 5JHTA 3ODHA 2FOKA 3FDEA 4AWMA 1SDOA 3V21A 3DWHA 3WVKA 3A4KA 4PW6A 3HW4A 4E5LA 3Q0FA 4E5JA 1FZRA 4F0QA 4E5IA 3BAMA 3CLZA 2ZKDA 1D2IA 4PW5A 5D8UA 4ZHZA
chains in the Genus database with same CATH topology
1VRRA 4R28A 1BAMA 3EBJA 4AWFA 3Q0CA 4NFZA 2P14A 5FDDA 3V20A 3MQ6A 5EGAA 2PFJA 5CGVA 5JHVA 3MQYA 5I13A 2BAMA 5DBSA 3DPGA 3Q0BX 5CZNA 3WVHA 5D42A 3WVGA 3N78A 4ZI0A 4AWHA 1DC1A 3HW5A 4CHCA 1BHMA 4E5EA 3HW6A 4E5HA 2EWFA 3DW9A 5D4GA 2XI7A 4E5FA 3V1ZA 3HW3A 4RZLA 5DEBA 4YYLA 5D9JA 4OC8A 1FOKA 1KNVA 4AWGA 3BM3A 2P0JA 5FDGA 2GB7A 5D2OA 2FQZA 3WVIA 1M0IA 4F0PA 4CGXA 3CAEA 5DESA 3N7BA 3Q0DA 4AVLA 4AVQA 3WVPA 1ES8A 1CFRA 4YGIA 4AVGA 1DFMA 5CL0A 5CCYA 3DVOA 4ZQQA 4CGSA 2XI5A 1ESGA 2E52A 4E5GA 4AWKA 1M0DA 5JHTA 3ODHA 2FOKA 4AWMA 1SDOA 3V21A 3WVKA 3A4KA 3HW4A 4E5LA 3Q0FA 4E5JA 1FZRA 4F0QA 4E5IA 3BAMA 1D2IA 5D8UA 4ZHZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RZL A;  4R28 A;  4F0P A;  4F0Q A;  4OC8 A; 
#chains in the Genus database with same CATH topology
 1VRR A;  2ZO2 B;  4R28 A;  1BAM A;  3EBJ A;  4AWF A;  3Q0C A;  4NFZ A;  2P14 A;  5FDD A;  3V20 A;  3MQ6 A;  5EGA A;  2PFJ A;  5CGV A;  2ZO0 B;  5JHV A;  3MQY A;  5I13 A;  2BAM A;  5DBS A;  3DPG A;  3Q0B X;  5CZN A;  3WVH A;  5D42 A;  3WVG A;  3N78 A;  4ZI0 A;  4AWH A;  1DC1 A;  3HW5 A;  4CHC A;  1BHM A;  4E5E A;  3HW6 A;  4E5H A;  2EWF A;  3DW9 A;  5D4G A;  2XI7 A;  4E5F A;  3F8I A;  3V1Z A;  3HW3 A;  4RZL A;  5DEB A;  4YYL A;  4NJ5 A;  2PB7 A;  2ZKG A;  5D9J A;  4OC8 A;  1FOK A;  1KNV A;  3F8J B;  4AWG A;  3BM3 A;  2P0J A;  5FDG A;  2GB7 A;  5D2O A;  2FQZ A;  3WVI A;  1M0I A;  4F0P A;  4PW7 A;  4CGX A;  3CAE A;  5DES A;  3N7B A;  3Q0D A;  4AVL A;  4AVQ A;  3WVP A;  2ZKE A;  1ES8 A;  1CFR A;  2ZO1 B;  4YGI A;  4AVG A;  1DFM A;  5CL0 A;  5CCY A;  3DVO A;  4ZQQ A;  3OLN A;  4CGS A;  2XI5 A;  1ESG A;  2E52 A;  4E5G A;  4AWK A;  2ZKF A;  1M0D A;  3BI7 A;  5JHT A;  3ODH A;  2FOK A;  3FDE A;  4AWM A;  1SDO A;  3V21 A;  3DWH A;  3WVK A;  3A4K A;  4PW6 A;  3HW4 A;  4E5L A;  3Q0F A;  4E5J A;  1FZR A;  4F0Q A;  4E5I A;  3BAM A;  3CLZ A;  2ZKD A;  1D2I A;  4PW5 A;  5D8U A;  4ZHZ A; 
#chains in the Genus database with same CATH homology
 1VRR A;  4R28 A;  1BAM A;  3EBJ A;  4AWF A;  3Q0C A;  4NFZ A;  2P14 A;  5FDD A;  3V20 A;  3MQ6 A;  5EGA A;  2PFJ A;  5CGV A;  5JHV A;  3MQY A;  5I13 A;  2BAM A;  5DBS A;  3DPG A;  3Q0B X;  5CZN A;  3WVH A;  5D42 A;  3WVG A;  3N78 A;  4ZI0 A;  4AWH A;  1DC1 A;  3HW5 A;  4CHC A;  1BHM A;  4E5E A;  3HW6 A;  4E5H A;  2EWF A;  3DW9 A;  5D4G A;  2XI7 A;  4E5F A;  3V1Z A;  3HW3 A;  4RZL A;  5DEB A;  4YYL A;  5D9J A;  4OC8 A;  1FOK A;  1KNV A;  4AWG A;  3BM3 A;  2P0J A;  5FDG A;  2GB7 A;  5D2O A;  2FQZ A;  3WVI A;  1M0I A;  4F0P A;  4CGX A;  3CAE A;  5DES A;  3N7B A;  3Q0D A;  4AVL A;  4AVQ A;  3WVP A;  1ES8 A;  1CFR A;  4YGI A;  4AVG A;  1DFM A;  5CL0 A;  5CCY A;  3DVO A;  4ZQQ A;  4CGS A;  2XI5 A;  1ESG A;  2E52 A;  4E5G A;  4AWK A;  1M0D A;  5JHT A;  3ODH A;  2FOK A;  4AWM A;  1SDO A;  3V21 A;  3WVK A;  3A4K A;  3HW4 A;  4E5L A;  3Q0F A;  4E5J A;  1FZR A;  4F0Q A;  4E5I A;  3BAM A;  1D2I A;  5D8U A;  4ZHZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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