4F0PA

Mspji restriction endonuclease - p31 form
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
450
structure length
450
Chain Sequence
DIAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium sp.
molecule keywords Restriction endonuclease
total genus 120
structure length 450
sequence length 450
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2012-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04471 Mrr_cat Restriction endonuclease
A PF18062 RE_AspBHI_N Restriction endonuclease AspBHI N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.20 Mainly Beta Roll PUA domain-like PUA domain-like 4f0pA01
3.40.91.100 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 4f0pA02
4F0PA 4RZLA 4OC8A 4R28A 4F0QA
chains in the Genus database with same CATH superfamily
3FDEA 4CGSA 3CAEA 3HW3A 3DWHA 1BHMA 5D4GA 4AWMA 3OLNA 1KNVA 1DC1A 2P0JA 5D42A 3N78A 3DPGA 4AVQA 2ZO2B 1ES8A 5FDDA 5CL0A 2PFJA 3Q0DA 4E5GA 2XI5A 3Q0CA 4ZHZA 5D9JA 1SDOA 5CCYA 4E5IA 3A4KA 2E52A 1FZRA 3MQYA 3BI7A 3HW5A 2ZKDA 5D8UA 3HW4A 1M0DA 4R28A 4CGXA 2PB7A 2ZO0B 4AVGA 1M0IA 1VRRA 3WVPA 2FOKA 1CFRA 3BAMA 4F0QA 3Q0FA 3V1ZA 2EWFA 5DEBA 3F8IA 2ZKEA 4AWKA 5CZNA 1FOKA 2GB7A 4RZLA 3WVHA 4OC8A 4CHCA 4E5HA 3ODHA 4PW6A 2XI7A 4ZQQA 4PW7A 4YYLA 4PW5A 3HW6A 4ZI0A 4YGIA 4NJ5A 2ZKFA 3V20A 5FDGA 3MQ6A 3CLZA 2FQZA 3WVKA 1BAMA 3N7BA 4NFZA 4E5JA 2ZO1B 1D2IA 5DBSA 2P14A 3DW9A 5JHTA 1DFMA 3WVIA 4AWFA 4AVLA 4E5FA 4AWGA 5JHVA 3F8JB 5D2OA 3DVOA 5CGVA 2BAMA 3V21A 4F0PA 2ZKGA 5I13A 1ESGA 4E5EA 4E5LA 5EGAA 3WVGA 3Q0BX 3BM3A 5DESA 4AWHA 3EBJA
chains in the Genus database with same CATH topology
4CGSA 3CAEA 3HW3A 1BHMA 5D4GA 4AWMA 1KNVA 1DC1A 2P0JA 5D42A 3N78A 3DPGA 4AVQA 1ES8A 5FDDA 5CL0A 2PFJA 3Q0DA 4E5GA 2XI5A 3Q0CA 4ZHZA 5D9JA 1SDOA 5CCYA 4E5IA 3A4KA 2E52A 1FZRA 3MQYA 3HW5A 5D8UA 3HW4A 1M0DA 4R28A 4CGXA 4AVGA 1M0IA 1VRRA 3WVPA 2FOKA 1CFRA 3BAMA 4F0QA 3Q0FA 3V1ZA 2EWFA 5DEBA 4AWKA 5CZNA 1FOKA 2GB7A 4RZLA 3WVHA 4OC8A 4CHCA 4E5HA 3ODHA 2XI7A 4ZQQA 4YYLA 3HW6A 4ZI0A 4YGIA 3V20A 5FDGA 3MQ6A 2FQZA 3WVKA 1BAMA 3EBJA 3N7BA 4NFZA 4E5JA 1D2IA 5DBSA 2P14A 3DW9A 5JHTA 1DFMA 3WVIA 4AWFA 4AVLA 4E5FA 4AWGA 5JHVA 5D2OA 3DVOA 5CGVA 2BAMA 3V21A 4F0PA 5I13A 1ESGA 4E5EA 5EGAA 3WVGA 3Q0BX 3BM3A 5DESA 4AWHA 4E5LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F0P A;  4RZL A;  4OC8 A;  4R28 A;  4F0Q A; 
#chains in the Genus database with same CATH topology
 3FDE A;  4CGS A;  3CAE A;  3HW3 A;  3DWH A;  1BHM A;  5D4G A;  4AWM A;  3OLN A;  1KNV A;  1DC1 A;  2P0J A;  5D42 A;  3N78 A;  3DPG A;  4AVQ A;  2ZO2 B;  1ES8 A;  5FDD A;  5CL0 A;  2PFJ A;  3Q0D A;  4E5G A;  2XI5 A;  3Q0C A;  4ZHZ A;  5D9J A;  1SDO A;  5CCY A;  4E5I A;  3A4K A;  2E52 A;  1FZR A;  3MQY A;  3BI7 A;  3HW5 A;  2ZKD A;  5D8U A;  3HW4 A;  1M0D A;  4R28 A;  4CGX A;  2PB7 A;  2ZO0 B;  4AVG A;  1M0I A;  1VRR A;  3WVP A;  2FOK A;  1CFR A;  3BAM A;  4F0Q A;  3Q0F A;  3V1Z A;  2EWF A;  5DEB A;  3F8I A;  2ZKE A;  4AWK A;  5CZN A;  1FOK A;  2GB7 A;  4RZL A;  3WVH A;  4OC8 A;  4CHC A;  4E5H A;  3ODH A;  4PW6 A;  2XI7 A;  4ZQQ A;  4PW7 A;  4YYL A;  4PW5 A;  3HW6 A;  4ZI0 A;  4YGI A;  4NJ5 A;  2ZKF A;  3V20 A;  5FDG A;  3MQ6 A;  3CLZ A;  2FQZ A;  3WVK A;  1BAM A;  3N7B A;  4NFZ A;  4E5J A;  2ZO1 B;  1D2I A;  5DBS A;  2P14 A;  3DW9 A;  5JHT A;  1DFM A;  3WVI A;  4AWF A;  4AVL A;  4E5F A;  4AWG A;  5JHV A;  3F8J B;  5D2O A;  3DVO A;  5CGV A;  2BAM A;  3V21 A;  4F0P A;  2ZKG A;  5I13 A;  1ESG A;  4E5E A;  4E5L A;  5EGA A;  3WVG A;  3Q0B X;  3BM3 A;  5DES A;  4AWH A;  3EBJ A; 
#chains in the Genus database with same CATH homology
 4CGS A;  3CAE A;  3HW3 A;  1BHM A;  5D4G A;  4AWM A;  1KNV A;  1DC1 A;  2P0J A;  5D42 A;  3N78 A;  3DPG A;  4AVQ A;  1ES8 A;  5FDD A;  5CL0 A;  2PFJ A;  3Q0D A;  4E5G A;  2XI5 A;  3Q0C A;  4ZHZ A;  5D9J A;  1SDO A;  5CCY A;  4E5I A;  3A4K A;  2E52 A;  1FZR A;  3MQY A;  3HW5 A;  5D8U A;  3HW4 A;  1M0D A;  4R28 A;  4CGX A;  4AVG A;  1M0I A;  1VRR A;  3WVP A;  2FOK A;  1CFR A;  3BAM A;  4F0Q A;  3Q0F A;  3V1Z A;  2EWF A;  5DEB A;  4AWK A;  5CZN A;  1FOK A;  2GB7 A;  4RZL A;  3WVH A;  4OC8 A;  4CHC A;  4E5H A;  3ODH A;  2XI7 A;  4ZQQ A;  4YYL A;  3HW6 A;  4ZI0 A;  4YGI A;  3V20 A;  5FDG A;  3MQ6 A;  2FQZ A;  3WVK A;  1BAM A;  3EBJ A;  3N7B A;  4NFZ A;  4E5J A;  1D2I A;  5DBS A;  2P14 A;  3DW9 A;  5JHT A;  1DFM A;  3WVI A;  4AWF A;  4AVL A;  4E5F A;  4AWG A;  5JHV A;  5D2O A;  3DVO A;  5CGV A;  2BAM A;  3V21 A;  4F0P A;  5I13 A;  1ESG A;  4E5E A;  5EGA A;  3WVG A;  3Q0B X;  3BM3 A;  5DES A;  4AWH A;  4E5L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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