4BB2A

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
337
structure length
332
Chain Sequence
HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFALEMTMGNALFLDGSLELLESFSADIAHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
publication title Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
pubmed doi rcsb
source organism Homo sapiens
total genus 98
structure length 332
sequence length 337
ec nomenclature
pdb deposition date 2012-09-19
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4bb2A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4bb2A01
3ZHAA 9APIA 1DZHL 1KCTA 9PAIA 4BB2A 1BY7A 1B3KA 4C49A 3DRUA 4IC0A 1DB2A 2B4XI 1XQGA 1LK6I 3R4LA 3H5CA 2B4XL 1LJ5A 3EOXA 3FGQA 2BEHI 4IF8A 2D26A 1D5SA 1JMJA 3PZFA 2ZV6A 1ATUA 3CWMA 1SR5A 1JTIA 2BEHL 2DUTA 1ATHA 2PEEA 5BRRI 4Y40A 2ACHA 5CDZA 1A7CA 1DZGI 4DY0A 1DVNA 1SEKA 1UHGA 5HGCA 1C5GA 1E04I 1PSIA 1M93B 4CAAA 7APIA 1F0CA 1QMBA 2VDYA 3F1SA 1R1LI 1OO8A 3EVJI 2ZNHA 4RO9A 2XN6A 3CWLA 3CVMA 3DRMA 4AU4A 4AU3B 8APIA 3KCGI 3Q03A 2VH4A 4ZK3A 3T1PA 1OVAA 1JJOC 1QMNA 1JVQI 1T1FA 3OZQA 4KDSA 3STOA 4G8RA 2WXZA 5CE0A 1LQ8A 2RIWA 3CAAA 5CDXA 1OPHA 2HIJI 2WXYC 3PB1I 4ROAA 4DTEA 3Q02A 2WY0C 2GD4C 2WXWA 1DZGL 1HP7A 1E05I 2OAYA 4AU2A 2PEFA 5EI0A 3F5NA 1AZXI 4EB1I 1XQJA 2ARRA 1SNGA 3DY0A 4P0FA 1BR8I 4PYWA 4AJTA 1OYHI 1JRRA 5INWA 2WY1A 3B9FI 1AS4A 1YXAA 3NDDA 4R9IA 1JMOA 1WZ9A 2ARQA 2R9YA 3DLWA 2OL2A 1NQ9I 2RIVA 2V95A 3UT3A 1K9OI 4RSQA 4Y3KA 2CEOA 3NE4A 4C41A 1DZHI 2WXXA 1TB6I 2VDXA 4AU3A 1MTPA 2ANTI 2B5TI 1OVAB 4AJUA 5IO1A 2H4RA 1ATTA 2HIJL 1QLPA 2H4PA 1XU8A 1OVAC 1ANTI 4AQHA 3F02A 1IMVA 1E03I 1EZXA 4GA7A 4DY7C 4P0OA 5C98A 4ZK0A 2XN7A 2WXZC 1C8OA 4EB1L 2XN5A 1HLEA 1OYHL 1IZ2A 2H4QA 4YIAA 3NDAA 1DVMA 1OC0A 2HI9A 2QUGA 4ROBA 3VVJA 4X30A 3NDFA 3LW2A 4G8OA 3LE2A 4AFXA 2XN3A
chains in the Genus database with same CATH superfamily
3ZHAA 9APIA 1DZHL 1KCTA 9PAIA 4BB2A 1BY7A 1B3KA 4C49A 3DRUA 4IC0A 1DB2A 2B4XI 1XQGA 1LK6I 3R4LA 3H5CA 2B4XL 1LJ5A 3EOXA 3FGQA 2BEHI 4IF8A 2D26A 1D5SA 1JMJA 3PZFA 2ZV6A 1ATUA 3CWMA 1SR5A 1JTIA 2BEHL 2DUTA 1ATHA 2PEEA 5BRRI 4Y40A 2ACHA 5CDZA 1A7CA 1DZGI 4DY0A 1DVNA 1SEKA 1UHGA 5HGCA 1C5GA 1E04I 1PSIA 1M93B 4CAAA 7APIA 1F0CA 1QMBA 2VDYA 3F1SA 1R1LI 1OO8A 3EVJI 2ZNHA 4RO9A 2XN6A 3CWLA 3CVMA 3DRMA 4AU4A 4AU3B 8APIA 3KCGI 3Q03A 2VH4A 4ZK3A 3T1PA 1OVAA 1JJOC 1QMNA 1JVQI 1T1FA 3OZQA 4KDSA 3STOA 4G8RA 2WXZA 5CE0A 1LQ8A 2RIWA 3CAAA 5CDXA 1OPHA 2HIJI 2WXYC 3PB1I 4ROAA 4DTEA 3Q02A 2WY0C 2GD4C 2WXWA 1DZGL 1HP7A 1E05I 2OAYA 4AU2A 2PEFA 5EI0A 3F5NA 1AZXI 4EB1I 1XQJA 2ARRA 1SNGA 3DY0A 4P0FA 1BR8I 4PYWA 4AJTA 1OYHI 1JRRA 5INWA 2WY1A 3B9FI 1AS4A 1YXAA 3NDDA 4R9IA 1JMOA 1WZ9A 2ARQA 2R9YA 3DLWA 2OL2A 1NQ9I 2RIVA 2V95A 3UT3A 1K9OI 4RSQA 4Y3KA 2CEOA 3NE4A 4C41A 1DZHI 2WXXA 1TB6I 2VDXA 4AU3A 1MTPA 2ANTI 2B5TI 1OVAB 4AJUA 5IO1A 2H4RA 1ATTA 2HIJL 1QLPA 2H4PA 1XU8A 1OVAC 1ANTI 4AQHA 3F02A 1IMVA 1E03I 1EZXA 4GA7A 4DY7C 4P0OA 5C98A 4ZK0A 2XN7A 2WXZC 1C8OA 4EB1L 2XN5A 1HLEA 1OYHL 1IZ2A 2H4QA 4YIAA 3NDAA 1DVMA 1OC0A 2HI9A 2QUGA 4ROBA 3VVJA 4X30A 3NDFA 3LW2A 4G8OA 3LE2A 4AFXA 2XN3A
chains in the Genus database with same CATH topology
3ZHAA 9APIA 1DZHL 1KCTA 9PAIA 4BB2A 1BY7A 1B3KA 4C49A 3DRUA 4IC0A 1DB2A 2B4XI 1XQGA 1LK6I 3R4LA 3H5CA 2B4XL 1LJ5A 3EOXA 3FGQA 2BEHI 4IF8A 2D26A 1D5SA 1JMJA 3PZFA 2ZV6A 1ATUA 3CWMA 1SR5A 1JTIA 2BEHL 2DUTA 1ATHA 2PEEA 5BRRI 4Y40A 2ACHA 5CDZA 1A7CA 1DZGI 4DY0A 1DVNA 1SEKA 1UHGA 5HGCA 1C5GA 1E04I 1PSIA 1M93B 4CAAA 7APIA 1F0CA 1QMBA 2VDYA 3F1SA 1R1LI 1OO8A 3EVJI 2ZNHA 4RO9A 2XN6A 3CWLA 3CVMA 3DRMA 4AU4A 4AU3B 8APIA 3KCGI 3Q03A 2VH4A 4ZK3A 3T1PA 1OVAA 1JJOC 1QMNA 1JVQI 1T1FA 3OZQA 4KDSA 3STOA 4G8RA 2WXZA 5CE0A 1LQ8A 2RIWA 3CAAA 5CDXA 1OPHA 2HIJI 2WXYC 3PB1I 4ROAA 4DTEA 3Q02A 2WY0C 2GD4C 2WXWA 1DZGL 1HP7A 1E05I 2OAYA 4AU2A 2PEFA 5EI0A 3F5NA 1AZXI 4EB1I 1XQJA 2ARRA 1SNGA 3DY0A 4P0FA 1BR8I 4PYWA 4AJTA 1OYHI 1JRRA 5INWA 2WY1A 3B9FI 1AS4A 1YXAA 3NDDA 4R9IA 1JMOA 1WZ9A 2ARQA 2R9YA 3DLWA 2OL2A 1NQ9I 2RIVA 2V95A 3UT3A 1K9OI 4RSQA 4Y3KA 2CEOA 3NE4A 4C41A 1DZHI 2WXXA 1TB6I 2VDXA 4AU3A 1MTPA 2ANTI 2B5TI 1OVAB 4AJUA 5IO1A 2H4RA 1ATTA 2HIJL 1QLPA 2H4PA 1XU8A 1OVAC 1ANTI 4AQHA 3F02A 1IMVA 1E03I 1EZXA 4GA7A 4DY7C 4P0OA 5C98A 4ZK0A 2XN7A 2WXZC 1C8OA 4EB1L 2XN5A 1HLEA 1OYHL 1IZ2A 2H4QA 4YIAA 3NDAA 1DVMA 1OC0A 2HI9A 2QUGA 4ROBA 3VVJA 4X30A 3NDFA 3LW2A 4G8OA 3LE2A 4AFXA 2XN3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZHA A;  9API A;  1DZH L;  1KCT A;  9PAI A;  4BB2 A;  1BY7 A;  1B3K A;  4C49 A;  3DRU A;  4IC0 A;  1DB2 A;  2B4X I;  1XQG A;  1LK6 I;  3R4L A;  3H5C A;  2B4X L;  1LJ5 A;  3EOX A;  3FGQ A;  2BEH I;  4IF8 A;  2D26 A;  1D5S A;  1JMJ A;  3PZF A;  2ZV6 A;  1ATU A;  3CWM A;  1SR5 A;  1JTI A;  2BEH L;  2DUT A;  1ATH A;  2PEE A;  5BRR I;  4Y40 A;  2ACH A;  5CDZ A;  1A7C A;  1DZG I;  4DY0 A;  1DVN A;  1SEK A;  1UHG A;  5HGC A;  1C5G A;  1E04 I;  1PSI A;  1M93 B;  4CAA A;  7API A;  1F0C A;  1QMB A;  2VDY A;  3F1S A;  1R1L I;  1OO8 A;  3EVJ I;  2ZNH A;  4RO9 A;  2XN6 A;  3CWL A;  3CVM A;  3DRM A;  4AU4 A;  4AU3 B;  8API A;  3KCG I;  3Q03 A;  2VH4 A;  4ZK3 A;  3T1P A;  1OVA A;  1JJO C;  1QMN A;  1JVQ I;  1T1F A;  3OZQ A;  4KDS A;  3STO A;  4G8R A;  2WXZ A;  5CE0 A;  1LQ8 A;  2RIW A;  3CAA A;  5CDX A;  1OPH A;  2HIJ I;  2WXY C;  3PB1 I;  4ROA A;  4DTE A;  3Q02 A;  2WY0 C;  2GD4 C;  2WXW A;  1DZG L;  1HP7 A;  1E05 I;  2OAY A;  4AU2 A;  2PEF A;  5EI0 A;  3F5N A;  1AZX I;  4EB1 I;  1XQJ A;  2ARR A;  1SNG A;  3DY0 A;  4P0F A;  1BR8 I;  4PYW A;  4AJT A;  1OYH I;  1JRR A;  5INW A;  2WY1 A;  3B9F I;  1AS4 A;  1YXA A;  3NDD A;  4R9I A;  1JMO A;  1WZ9 A;  2ARQ A;  2R9Y A;  3DLW A;  2OL2 A;  1NQ9 I;  2RIV A;  2V95 A;  3UT3 A;  1K9O I;  4RSQ A;  4Y3K A;  2CEO A;  3NE4 A;  4C41 A;  1DZH I;  2WXX A;  1TB6 I;  2VDX A;  4AU3 A;  1MTP A;  2ANT I;  2B5T I;  1OVA B;  4AJU A;  5IO1 A;  2H4R A;  1ATT A;  2HIJ L;  1QLP A;  2H4P A;  1XU8 A;  1OVA C;  1ANT I;  4AQH A;  3F02 A;  1IMV A;  1E03 I;  1EZX A;  4GA7 A;  4DY7 C;  4P0O A;  5C98 A;  4ZK0 A;  2XN7 A;  2WXZ C;  1C8O A;  4EB1 L;  2XN5 A;  1HLE A;  1OYH L;  1IZ2 A;  2H4Q A;  4YIA A;  3NDA A;  1DVM A;  1OC0 A;  2HI9 A;  2QUG A;  4ROB A;  3VVJ A;  4X30 A;  3NDF A;  3LW2 A;  4G8O A;  3LE2 A;  4AFX A;  2XN3 A; 
#chains in the Genus database with same CATH topology
 3ZHA A;  9API A;  1DZH L;  1KCT A;  9PAI A;  4BB2 A;  1BY7 A;  1B3K A;  4C49 A;  3DRU A;  4IC0 A;  1DB2 A;  2B4X I;  1XQG A;  1LK6 I;  3R4L A;  3H5C A;  2B4X L;  1LJ5 A;  3EOX A;  3FGQ A;  2BEH I;  4IF8 A;  2D26 A;  1D5S A;  1JMJ A;  3PZF A;  2ZV6 A;  1ATU A;  3CWM A;  1SR5 A;  1JTI A;  2BEH L;  2DUT A;  1ATH A;  2PEE A;  5BRR I;  4Y40 A;  2ACH A;  5CDZ A;  1A7C A;  1DZG I;  4DY0 A;  1DVN A;  1SEK A;  1UHG A;  5HGC A;  1C5G A;  1E04 I;  1PSI A;  1M93 B;  4CAA A;  7API A;  1F0C A;  1QMB A;  2VDY A;  3F1S A;  1R1L I;  1OO8 A;  3EVJ I;  2ZNH A;  4RO9 A;  2XN6 A;  3CWL A;  3CVM A;  3DRM A;  4AU4 A;  4AU3 B;  8API A;  3KCG I;  3Q03 A;  2VH4 A;  4ZK3 A;  3T1P A;  1OVA A;  1JJO C;  1QMN A;  1JVQ I;  1T1F A;  3OZQ A;  4KDS A;  3STO A;  4G8R A;  2WXZ A;  5CE0 A;  1LQ8 A;  2RIW A;  3CAA A;  5CDX A;  1OPH A;  2HIJ I;  2WXY C;  3PB1 I;  4ROA A;  4DTE A;  3Q02 A;  2WY0 C;  2GD4 C;  2WXW A;  1DZG L;  1HP7 A;  1E05 I;  2OAY A;  4AU2 A;  2PEF A;  5EI0 A;  3F5N A;  1AZX I;  4EB1 I;  1XQJ A;  2ARR A;  1SNG A;  3DY0 A;  4P0F A;  1BR8 I;  4PYW A;  4AJT A;  1OYH I;  1JRR A;  5INW A;  2WY1 A;  3B9F I;  1AS4 A;  1YXA A;  3NDD A;  4R9I A;  1JMO A;  1WZ9 A;  2ARQ A;  2R9Y A;  3DLW A;  2OL2 A;  1NQ9 I;  2RIV A;  2V95 A;  3UT3 A;  1K9O I;  4RSQ A;  4Y3K A;  2CEO A;  3NE4 A;  4C41 A;  1DZH I;  2WXX A;  1TB6 I;  2VDX A;  4AU3 A;  1MTP A;  2ANT I;  2B5T I;  1OVA B;  4AJU A;  5IO1 A;  2H4R A;  1ATT A;  2HIJ L;  1QLP A;  2H4P A;  1XU8 A;  1OVA C;  1ANT I;  4AQH A;  3F02 A;  1IMV A;  1E03 I;  1EZX A;  4GA7 A;  4DY7 C;  4P0O A;  5C98 A;  4ZK0 A;  2XN7 A;  2WXZ C;  1C8O A;  4EB1 L;  2XN5 A;  1HLE A;  1OYH L;  1IZ2 A;  2H4Q A;  4YIA A;  3NDA A;  1DVM A;  1OC0 A;  2HI9 A;  2QUG A;  4ROB A;  3VVJ A;  4X30 A;  3NDF A;  3LW2 A;  4G8O A;  3LE2 A;  4AFX A;  2XN3 A; 
#chains in the Genus database with same CATH homology
 3ZHA A;  9API A;  1DZH L;  1KCT A;  9PAI A;  4BB2 A;  1BY7 A;  1B3K A;  4C49 A;  3DRU A;  4IC0 A;  1DB2 A;  2B4X I;  1XQG A;  1LK6 I;  3R4L A;  3H5C A;  2B4X L;  1LJ5 A;  3EOX A;  3FGQ A;  2BEH I;  4IF8 A;  2D26 A;  1D5S A;  1JMJ A;  3PZF A;  2ZV6 A;  1ATU A;  3CWM A;  1SR5 A;  1JTI A;  2BEH L;  2DUT A;  1ATH A;  2PEE A;  5BRR I;  4Y40 A;  2ACH A;  5CDZ A;  1A7C A;  1DZG I;  4DY0 A;  1DVN A;  1SEK A;  1UHG A;  5HGC A;  1C5G A;  1E04 I;  1PSI A;  1M93 B;  4CAA A;  7API A;  1F0C A;  1QMB A;  2VDY A;  3F1S A;  1R1L I;  1OO8 A;  3EVJ I;  2ZNH A;  4RO9 A;  2XN6 A;  3CWL A;  3CVM A;  3DRM A;  4AU4 A;  4AU3 B;  8API A;  3KCG I;  3Q03 A;  2VH4 A;  4ZK3 A;  3T1P A;  1OVA A;  1JJO C;  1QMN A;  1JVQ I;  1T1F A;  3OZQ A;  4KDS A;  3STO A;  4G8R A;  2WXZ A;  5CE0 A;  1LQ8 A;  2RIW A;  3CAA A;  5CDX A;  1OPH A;  2HIJ I;  2WXY C;  3PB1 I;  4ROA A;  4DTE A;  3Q02 A;  2WY0 C;  2GD4 C;  2WXW A;  1DZG L;  1HP7 A;  1E05 I;  2OAY A;  4AU2 A;  2PEF A;  5EI0 A;  3F5N A;  1AZX I;  4EB1 I;  1XQJ A;  2ARR A;  1SNG A;  3DY0 A;  4P0F A;  1BR8 I;  4PYW A;  4AJT A;  1OYH I;  1JRR A;  5INW A;  2WY1 A;  3B9F I;  1AS4 A;  1YXA A;  3NDD A;  4R9I A;  1JMO A;  1WZ9 A;  2ARQ A;  2R9Y A;  3DLW A;  2OL2 A;  1NQ9 I;  2RIV A;  2V95 A;  3UT3 A;  1K9O I;  4RSQ A;  4Y3K A;  2CEO A;  3NE4 A;  4C41 A;  1DZH I;  2WXX A;  1TB6 I;  2VDX A;  4AU3 A;  1MTP A;  2ANT I;  2B5T I;  1OVA B;  4AJU A;  5IO1 A;  2H4R A;  1ATT A;  2HIJ L;  1QLP A;  2H4P A;  1XU8 A;  1OVA C;  1ANT I;  4AQH A;  3F02 A;  1IMV A;  1E03 I;  1EZX A;  4GA7 A;  4DY7 C;  4P0O A;  5C98 A;  4ZK0 A;  2XN7 A;  2WXZ C;  1C8O A;  4EB1 L;  2XN5 A;  1HLE A;  1OYH L;  1IZ2 A;  2H4Q A;  4YIA A;  3NDA A;  1DVM A;  1OC0 A;  2HI9 A;  2QUG A;  4ROB A;  3VVJ A;  4X30 A;  3NDF A;  3LW2 A;  4G8O A;  3LE2 A;  4AFX A;  2XN3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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