4C41A

Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236
Total Genus 117
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
369
structure length
367
Chain Sequence
RGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTCLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYCGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLRPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents.
pubmed doi rcsb
molecule tags Transport protein
source organism Homo sapiens
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
total genus 117
structure length 367
sequence length 369
ec nomenclature
pdb deposition date 2013-08-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4c41A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4c41A01
3T1PA 1ATTA 3DRUA 1ATHA 3UT3A 4DY0A 3PB1I 1TB6I 4EB1L 1DVMA 1R1LI 2CEOA 4KDSA 4BB2A 1XQGA 2ZNHA 2HIJI 2WXZA 3R4LA 1T1FA 2B5TI 1M93B 1AZXI 2B4XI 4C49A 1D5SA 4PYWA 3OZQA 5C98A 1BY7A 1NQ9I 2WXYC 3CWMA 3KCGI 3F1SA 3VVJA 8APIA 2WY1A 1QMNA 2DUTA 4RSQA 1HP7A 1SR5A 2HIJL 3NDAA 1DVNA 4Y40A 5IO1A 1SEKA 4X30A 4ZK3A 1C5GA 1OVAC 1DZGI 1JMOA 3PZFA 1E05I 1UHGA 1KCTA 1C8OA 2ZV6A 4P0OA 1QLPA 4RO9A 3F02A 3F5NA 2XN7A 4P0FA 2RIVA 1DZGL 1OPHA 1ATUA 3CWLA 4ROAA 4DTEA 2VDXA 4C41A 1LQ8A 2VH4A 1XQJA 3DY0A 2XN5A 4AU2A 5EI0A 2PEFA 2R9YA 1K9OI 2H4PA 9APIA 2HI9A 4AU4A 1OVAA 1OC0A 2RIWA 1XU8A 3NDDA 1OVAB 1B3KA 2XN3A 4CAAA 2WXWA 3EVJI 3Q02A 2BEHL 1E03I 3B9FI 1JMJA 1EZXA 4G8OA 3STOA 1AS4A 5CDXA 2PEEA 2V95A 2ARRA 2H4QA 2ANTI 2XN6A 1IZ2A 2D26A 1ANTI 3CVMA 1JJOC 3DLWA 2QUGA 3ZHAA 4AJUA 3EOXA 1BR8I 1A7CA 2WXXA 2BEHI 5CE0A 1PSIA 3LW2A 4AU3B 2VDYA 1OYHL 2GD4C 3NE4A 3CAAA 5BRRI 3DRMA 1YXAA 1LK6I 1IMVA 7APIA 2OL2A 4ROBA 4AJTA 4R9IA 1F0CA 5CDZA 1QMBA 1HLEA 1E04I 2H4RA 1JTIA 1LJ5A 1WZ9A 4DY7C 2OAYA 1SNGA 3LE2A 4IF8A 4G8RA 3Q03A 2WXZC 4Y3KA 9PAIA 1DB2A 1OO8A 1OYHI 1JVQI 3H5CA 1DZHI 3NDFA 4AFXA 4YIAA 5INWA 1MTPA 2B4XL 4IC0A 4AU3A 4ZK0A 2ARQA 2WY0C 4GA7A 2ACHA 4AQHA 1JRRA 5HGCA 4EB1I 3FGQA 1DZHL
chains in the Genus database with same CATH superfamily
3T1PA 1ATTA 3DRUA 1ATHA 3UT3A 4DY0A 3PB1I 1TB6I 4EB1L 1DVMA 1R1LI 2CEOA 4KDSA 4BB2A 1XQGA 2ZNHA 2HIJI 2WXZA 3R4LA 1T1FA 2B5TI 1M93B 1AZXI 2B4XI 4C49A 1D5SA 4PYWA 3OZQA 5C98A 1BY7A 1NQ9I 2WXYC 3CWMA 3KCGI 3F1SA 3VVJA 8APIA 2WY1A 1QMNA 2DUTA 4RSQA 1HP7A 1SR5A 2HIJL 3NDAA 1DVNA 4Y40A 5IO1A 1SEKA 4X30A 4ZK3A 1C5GA 1OVAC 1DZGI 1JMOA 3PZFA 1E05I 1UHGA 1KCTA 1C8OA 2ZV6A 4P0OA 1QLPA 4RO9A 3F02A 3F5NA 2XN7A 4P0FA 2RIVA 1DZGL 1OPHA 1ATUA 3CWLA 4ROAA 4DTEA 2VDXA 4C41A 1LQ8A 2VH4A 1XQJA 3DY0A 2XN5A 4AU2A 5EI0A 2PEFA 2R9YA 1K9OI 2H4PA 9APIA 2HI9A 4AU4A 1OVAA 1OC0A 2RIWA 1XU8A 3NDDA 1OVAB 1B3KA 2XN3A 4CAAA 2WXWA 3EVJI 3Q02A 2BEHL 1E03I 3B9FI 1JMJA 1EZXA 4G8OA 3STOA 1AS4A 5CDXA 2PEEA 2V95A 2ARRA 2H4QA 2ANTI 2XN6A 1IZ2A 2D26A 1ANTI 3CVMA 1JJOC 3DLWA 2QUGA 3ZHAA 4AJUA 3EOXA 1BR8I 1A7CA 2WXXA 2BEHI 5CE0A 1PSIA 3LW2A 4AU3B 2VDYA 1OYHL 2GD4C 3NE4A 3CAAA 5BRRI 3DRMA 1YXAA 1LK6I 1IMVA 7APIA 2OL2A 4ROBA 4AJTA 4R9IA 1F0CA 5CDZA 1QMBA 1HLEA 1E04I 2H4RA 1JTIA 1LJ5A 1WZ9A 4DY7C 2OAYA 1SNGA 3LE2A 4IF8A 4G8RA 3Q03A 2WXZC 4Y3KA 9PAIA 1DB2A 1OO8A 1OYHI 1JVQI 3H5CA 1DZHI 3NDFA 4AFXA 4YIAA 5INWA 1MTPA 2B4XL 4IC0A 4AU3A 4ZK0A 2ARQA 2WY0C 4GA7A 2ACHA 4AQHA 1JRRA 5HGCA 4EB1I 3FGQA 1DZHL
chains in the Genus database with same CATH topology
3T1PA 1ATTA 3DRUA 1ATHA 3UT3A 4DY0A 3PB1I 1TB6I 4EB1L 1DVMA 1R1LI 2CEOA 4KDSA 4BB2A 1XQGA 2ZNHA 2HIJI 2WXZA 3R4LA 1T1FA 2B5TI 1M93B 1AZXI 2B4XI 4C49A 1D5SA 4PYWA 3OZQA 5C98A 1BY7A 1NQ9I 2WXYC 3CWMA 3KCGI 3F1SA 3VVJA 8APIA 2WY1A 1QMNA 2DUTA 4RSQA 1HP7A 1SR5A 2HIJL 3NDAA 1DVNA 4Y40A 5IO1A 1SEKA 4X30A 4ZK3A 1C5GA 1OVAC 1DZGI 1JMOA 3PZFA 1E05I 1UHGA 1KCTA 1C8OA 2ZV6A 4P0OA 1QLPA 4RO9A 3F02A 3F5NA 2XN7A 4P0FA 2RIVA 1DZGL 1OPHA 1ATUA 3CWLA 4ROAA 4DTEA 2VDXA 4C41A 1LQ8A 2VH4A 1XQJA 3DY0A 2XN5A 4AU2A 5EI0A 2PEFA 2R9YA 1K9OI 2H4PA 9APIA 2HI9A 4AU4A 1OVAA 1OC0A 2RIWA 1XU8A 3NDDA 1OVAB 1B3KA 2XN3A 4CAAA 2WXWA 3EVJI 3Q02A 2BEHL 1E03I 3B9FI 1JMJA 1EZXA 4G8OA 3STOA 1AS4A 5CDXA 2PEEA 2V95A 2ARRA 2H4QA 2ANTI 2XN6A 1IZ2A 2D26A 1ANTI 3CVMA 1JJOC 3DLWA 2QUGA 3ZHAA 4AJUA 3EOXA 1BR8I 1A7CA 2WXXA 2BEHI 5CE0A 1PSIA 3LW2A 4AU3B 2VDYA 1OYHL 2GD4C 3NE4A 3CAAA 5BRRI 3DRMA 1YXAA 1LK6I 1IMVA 7APIA 2OL2A 4ROBA 4AJTA 4R9IA 1F0CA 5CDZA 1QMBA 1HLEA 1E04I 2H4RA 1JTIA 1LJ5A 1WZ9A 4DY7C 2OAYA 1SNGA 3LE2A 4IF8A 4G8RA 3Q03A 2WXZC 4Y3KA 9PAIA 1DB2A 1OO8A 1OYHI 1JVQI 3H5CA 1DZHI 3NDFA 4AFXA 4YIAA 5INWA 1MTPA 2B4XL 4IC0A 4AU3A 4ZK0A 2ARQA 2WY0C 4GA7A 2ACHA 4AQHA 1JRRA 5HGCA 4EB1I 3FGQA 1DZHL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T1P A;  1ATT A;  3DRU A;  1ATH A;  3UT3 A;  4DY0 A;  3PB1 I;  1TB6 I;  4EB1 L;  1DVM A;  1R1L I;  2CEO A;  4KDS A;  4BB2 A;  1XQG A;  2ZNH A;  2HIJ I;  2WXZ A;  3R4L A;  1T1F A;  2B5T I;  1M93 B;  1AZX I;  2B4X I;  4C49 A;  1D5S A;  4PYW A;  3OZQ A;  5C98 A;  1BY7 A;  1NQ9 I;  2WXY C;  3CWM A;  3KCG I;  3F1S A;  3VVJ A;  8API A;  2WY1 A;  1QMN A;  2DUT A;  4RSQ A;  1HP7 A;  1SR5 A;  2HIJ L;  3NDA A;  1DVN A;  4Y40 A;  5IO1 A;  1SEK A;  4X30 A;  4ZK3 A;  1C5G A;  1OVA C;  1DZG I;  1JMO A;  3PZF A;  1E05 I;  1UHG A;  1KCT A;  1C8O A;  2ZV6 A;  4P0O A;  1QLP A;  4RO9 A;  3F02 A;  3F5N A;  2XN7 A;  4P0F A;  2RIV A;  1DZG L;  1OPH A;  1ATU A;  3CWL A;  4ROA A;  4DTE A;  2VDX A;  4C41 A;  1LQ8 A;  2VH4 A;  1XQJ A;  3DY0 A;  2XN5 A;  4AU2 A;  5EI0 A;  2PEF A;  2R9Y A;  1K9O I;  2H4P A;  9API A;  2HI9 A;  4AU4 A;  1OVA A;  1OC0 A;  2RIW A;  1XU8 A;  3NDD A;  1OVA B;  1B3K A;  2XN3 A;  4CAA A;  2WXW A;  3EVJ I;  3Q02 A;  2BEH L;  1E03 I;  3B9F I;  1JMJ A;  1EZX A;  4G8O A;  3STO A;  1AS4 A;  5CDX A;  2PEE A;  2V95 A;  2ARR A;  2H4Q A;  2ANT I;  2XN6 A;  1IZ2 A;  2D26 A;  1ANT I;  3CVM A;  1JJO C;  3DLW A;  2QUG A;  3ZHA A;  4AJU A;  3EOX A;  1BR8 I;  1A7C A;  2WXX A;  2BEH I;  5CE0 A;  1PSI A;  3LW2 A;  4AU3 B;  2VDY A;  1OYH L;  2GD4 C;  3NE4 A;  3CAA A;  5BRR I;  3DRM A;  1YXA A;  1LK6 I;  1IMV A;  7API A;  2OL2 A;  4ROB A;  4AJT A;  4R9I A;  1F0C A;  5CDZ A;  1QMB A;  1HLE A;  1E04 I;  2H4R A;  1JTI A;  1LJ5 A;  1WZ9 A;  4DY7 C;  2OAY A;  1SNG A;  3LE2 A;  4IF8 A;  4G8R A;  3Q03 A;  2WXZ C;  4Y3K A;  9PAI A;  1DB2 A;  1OO8 A;  1OYH I;  1JVQ I;  3H5C A;  1DZH I;  3NDF A;  4AFX A;  4YIA A;  5INW A;  1MTP A;  2B4X L;  4IC0 A;  4AU3 A;  4ZK0 A;  2ARQ A;  2WY0 C;  4GA7 A;  2ACH A;  4AQH A;  1JRR A;  5HGC A;  4EB1 I;  3FGQ A;  1DZH L; 
#chains in the Genus database with same CATH topology
 3T1P A;  1ATT A;  3DRU A;  1ATH A;  3UT3 A;  4DY0 A;  3PB1 I;  1TB6 I;  4EB1 L;  1DVM A;  1R1L I;  2CEO A;  4KDS A;  4BB2 A;  1XQG A;  2ZNH A;  2HIJ I;  2WXZ A;  3R4L A;  1T1F A;  2B5T I;  1M93 B;  1AZX I;  2B4X I;  4C49 A;  1D5S A;  4PYW A;  3OZQ A;  5C98 A;  1BY7 A;  1NQ9 I;  2WXY C;  3CWM A;  3KCG I;  3F1S A;  3VVJ A;  8API A;  2WY1 A;  1QMN A;  2DUT A;  4RSQ A;  1HP7 A;  1SR5 A;  2HIJ L;  3NDA A;  1DVN A;  4Y40 A;  5IO1 A;  1SEK A;  4X30 A;  4ZK3 A;  1C5G A;  1OVA C;  1DZG I;  1JMO A;  3PZF A;  1E05 I;  1UHG A;  1KCT A;  1C8O A;  2ZV6 A;  4P0O A;  1QLP A;  4RO9 A;  3F02 A;  3F5N A;  2XN7 A;  4P0F A;  2RIV A;  1DZG L;  1OPH A;  1ATU A;  3CWL A;  4ROA A;  4DTE A;  2VDX A;  4C41 A;  1LQ8 A;  2VH4 A;  1XQJ A;  3DY0 A;  2XN5 A;  4AU2 A;  5EI0 A;  2PEF A;  2R9Y A;  1K9O I;  2H4P A;  9API A;  2HI9 A;  4AU4 A;  1OVA A;  1OC0 A;  2RIW A;  1XU8 A;  3NDD A;  1OVA B;  1B3K A;  2XN3 A;  4CAA A;  2WXW A;  3EVJ I;  3Q02 A;  2BEH L;  1E03 I;  3B9F I;  1JMJ A;  1EZX A;  4G8O A;  3STO A;  1AS4 A;  5CDX A;  2PEE A;  2V95 A;  2ARR A;  2H4Q A;  2ANT I;  2XN6 A;  1IZ2 A;  2D26 A;  1ANT I;  3CVM A;  1JJO C;  3DLW A;  2QUG A;  3ZHA A;  4AJU A;  3EOX A;  1BR8 I;  1A7C A;  2WXX A;  2BEH I;  5CE0 A;  1PSI A;  3LW2 A;  4AU3 B;  2VDY A;  1OYH L;  2GD4 C;  3NE4 A;  3CAA A;  5BRR I;  3DRM A;  1YXA A;  1LK6 I;  1IMV A;  7API A;  2OL2 A;  4ROB A;  4AJT A;  4R9I A;  1F0C A;  5CDZ A;  1QMB A;  1HLE A;  1E04 I;  2H4R A;  1JTI A;  1LJ5 A;  1WZ9 A;  4DY7 C;  2OAY A;  1SNG A;  3LE2 A;  4IF8 A;  4G8R A;  3Q03 A;  2WXZ C;  4Y3K A;  9PAI A;  1DB2 A;  1OO8 A;  1OYH I;  1JVQ I;  3H5C A;  1DZH I;  3NDF A;  4AFX A;  4YIA A;  5INW A;  1MTP A;  2B4X L;  4IC0 A;  4AU3 A;  4ZK0 A;  2ARQ A;  2WY0 C;  4GA7 A;  2ACH A;  4AQH A;  1JRR A;  5HGC A;  4EB1 I;  3FGQ A;  1DZH L; 
#chains in the Genus database with same CATH homology
 3T1P A;  1ATT A;  3DRU A;  1ATH A;  3UT3 A;  4DY0 A;  3PB1 I;  1TB6 I;  4EB1 L;  1DVM A;  1R1L I;  2CEO A;  4KDS A;  4BB2 A;  1XQG A;  2ZNH A;  2HIJ I;  2WXZ A;  3R4L A;  1T1F A;  2B5T I;  1M93 B;  1AZX I;  2B4X I;  4C49 A;  1D5S A;  4PYW A;  3OZQ A;  5C98 A;  1BY7 A;  1NQ9 I;  2WXY C;  3CWM A;  3KCG I;  3F1S A;  3VVJ A;  8API A;  2WY1 A;  1QMN A;  2DUT A;  4RSQ A;  1HP7 A;  1SR5 A;  2HIJ L;  3NDA A;  1DVN A;  4Y40 A;  5IO1 A;  1SEK A;  4X30 A;  4ZK3 A;  1C5G A;  1OVA C;  1DZG I;  1JMO A;  3PZF A;  1E05 I;  1UHG A;  1KCT A;  1C8O A;  2ZV6 A;  4P0O A;  1QLP A;  4RO9 A;  3F02 A;  3F5N A;  2XN7 A;  4P0F A;  2RIV A;  1DZG L;  1OPH A;  1ATU A;  3CWL A;  4ROA A;  4DTE A;  2VDX A;  4C41 A;  1LQ8 A;  2VH4 A;  1XQJ A;  3DY0 A;  2XN5 A;  4AU2 A;  5EI0 A;  2PEF A;  2R9Y A;  1K9O I;  2H4P A;  9API A;  2HI9 A;  4AU4 A;  1OVA A;  1OC0 A;  2RIW A;  1XU8 A;  3NDD A;  1OVA B;  1B3K A;  2XN3 A;  4CAA A;  2WXW A;  3EVJ I;  3Q02 A;  2BEH L;  1E03 I;  3B9F I;  1JMJ A;  1EZX A;  4G8O A;  3STO A;  1AS4 A;  5CDX A;  2PEE A;  2V95 A;  2ARR A;  2H4Q A;  2ANT I;  2XN6 A;  1IZ2 A;  2D26 A;  1ANT I;  3CVM A;  1JJO C;  3DLW A;  2QUG A;  3ZHA A;  4AJU A;  3EOX A;  1BR8 I;  1A7C A;  2WXX A;  2BEH I;  5CE0 A;  1PSI A;  3LW2 A;  4AU3 B;  2VDY A;  1OYH L;  2GD4 C;  3NE4 A;  3CAA A;  5BRR I;  3DRM A;  1YXA A;  1LK6 I;  1IMV A;  7API A;  2OL2 A;  4ROB A;  4AJT A;  4R9I A;  1F0C A;  5CDZ A;  1QMB A;  1HLE A;  1E04 I;  2H4R A;  1JTI A;  1LJ5 A;  1WZ9 A;  4DY7 C;  2OAY A;  1SNG A;  3LE2 A;  4IF8 A;  4G8R A;  3Q03 A;  2WXZ C;  4Y3K A;  9PAI A;  1DB2 A;  1OO8 A;  1OYH I;  1JVQ I;  3H5C A;  1DZH I;  3NDF A;  4AFX A;  4YIA A;  5INW A;  1MTP A;  2B4X L;  4IC0 A;  4AU3 A;  4ZK0 A;  2ARQ A;  2WY0 C;  4GA7 A;  2ACH A;  4AQH A;  1JRR A;  5HGC A;  4EB1 I;  3FGQ A;  1DZH L; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...