4C49A

Reactive loop cleaved human cbg in complex with cortisol
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
368
structure length
367
Chain Sequence
GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLRKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords CORTICOSTEROID-BINDING GLOBULIN
publication title Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg
rcsb
source organism Homo sapiens
total genus 105
structure length 367
sequence length 368
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 4c49A02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 4c49A01
4RSQA 1DVNA 4AU2A 1QLPA 2WXWA 3Q03A 1EZXA 1OPHA 1OC0A 1LK6I 1ATUA 2BEHL 3DY0A 1E03I 3B9FI 3F1SA 1DZGL 1OO8A 3R4LA 1DZHI 2VDYA 3F02A 4ROAA 2OAYA 5CE0A 1C5GA 4R9IA 4G8RA 2D26A 4IF8A 3NE4A 2XN5A 1DB2A 1SR5A 1WZ9A 1KCTA 1C8OA 3CWMA 5CDZA 1D5SA 2XN6A 5EI0A 3NDAA 1JVQI 4AFXA 5CDXA 4AQHA 3F5NA 4DTEA 3NDFA 2HIJI 5HGCA 4DY7C 2WXYC 4Y40A 1ANTI 1AZXI 2ZNHA 1PSIA 1JMOA 2WXZC 1TB6I 3NDDA 1LQ8A 5BRRI 1HLEA 2DUTA 4AU3A 3PZFA 4G8OA 2WY1A 3DRMA 2VH4A 7APIA 2ZV6A 4DY0A 3STOA 2ARRA 3UT3A 2B4XL 3DRUA 1XQJA 1IMVA 1OVAB 2PEFA 2QUGA 2RIWA 2WXXA 3FGQA 3ZHAA 2PEEA 4P0FA 1NQ9I 1E04I 1YXAA 1LJ5A 4ZK3A 9APIA 2VDXA 9PAIA 1XQGA 2R9YA 3CAAA 4IC0A 3VVJA 1IZ2A 2H4RA 4Y3KA 4AU3B 1XU8A 1JJOC 2B5TI 3H5CA 2ANTI 4C49A 1OVAA 2ARQA 2BEHI 3CVMA 1QMBA 1DVMA 1OYHL 1DZGI 1E05I 2WY0C 5C98A 3EOXA 4ROBA 2ACHA 2XN3A 3DLWA 5IO1A 1MTPA 1OVAC 5INWA 2RIVA 4CAAA 4GA7A 1T1FA 4P0OA 4AU4A 3EVJI 4KDSA 1JMJA 3CWLA 4PYWA 3Q02A 3T1PA 1SEKA 1UHGA 2HI9A 4EB1L 1ATTA 1JTIA 2OL2A 2HIJL 1OYHI 4YIAA 3LE2A 2H4PA 1BR8I 2V95A 4ZK0A 3LW2A 4X30A 1M93B 3OZQA 4AJUA 3KCGI 1F0CA 4BB2A 1K9OI 2XN7A 1R1LI 4AJTA 1ATHA 1B3KA 1DZHL 2B4XI 1QMNA 1BY7A 4RO9A 4C41A 3PB1I 4EB1I 1JRRA 1AS4A 1A7CA 1SNGA 8APIA 2CEOA 2WXZA 1HP7A 2H4QA 2GD4C
chains in the Genus database with same CATH superfamily
4RSQA 1DVNA 4AU2A 1QLPA 2WXWA 3Q03A 1EZXA 1OPHA 1OC0A 1LK6I 1ATUA 2BEHL 3DY0A 1E03I 3B9FI 3F1SA 1DZGL 1OO8A 3R4LA 1DZHI 2VDYA 3F02A 4ROAA 2OAYA 5CE0A 1C5GA 4R9IA 4G8RA 2D26A 4IF8A 3NE4A 2XN5A 1DB2A 1SR5A 1WZ9A 1KCTA 1C8OA 3CWMA 5CDZA 1D5SA 2XN6A 5EI0A 3NDAA 1JVQI 4AFXA 5CDXA 4AQHA 3F5NA 4DTEA 3NDFA 2HIJI 5HGCA 4DY7C 2WXYC 4Y40A 1ANTI 1AZXI 2ZNHA 1PSIA 1JMOA 2WXZC 1TB6I 3NDDA 1LQ8A 5BRRI 1HLEA 2DUTA 4AU3A 3PZFA 4G8OA 2WY1A 3DRMA 2VH4A 7APIA 2ZV6A 4DY0A 3STOA 2ARRA 3UT3A 2B4XL 3DRUA 1XQJA 1IMVA 1OVAB 2PEFA 2QUGA 2RIWA 2WXXA 3FGQA 3ZHAA 2PEEA 4P0FA 1NQ9I 1E04I 1YXAA 1LJ5A 4ZK3A 9APIA 2VDXA 9PAIA 1XQGA 2R9YA 3CAAA 4IC0A 3VVJA 1IZ2A 2H4RA 4Y3KA 4AU3B 1XU8A 1JJOC 2B5TI 3H5CA 2ANTI 4C49A 1OVAA 2ARQA 2BEHI 3CVMA 1QMBA 1DVMA 1OYHL 1DZGI 1E05I 2WY0C 5C98A 3EOXA 4ROBA 2ACHA 2XN3A 3DLWA 5IO1A 1MTPA 1OVAC 5INWA 2RIVA 4CAAA 4GA7A 1T1FA 4P0OA 4AU4A 3EVJI 4KDSA 1JMJA 3CWLA 4PYWA 3Q02A 3T1PA 1SEKA 1UHGA 2HI9A 4EB1L 1ATTA 1JTIA 2OL2A 2HIJL 1OYHI 4YIAA 3LE2A 2H4PA 1BR8I 2V95A 4ZK0A 3LW2A 4X30A 1M93B 3OZQA 4AJUA 3KCGI 1F0CA 4BB2A 1K9OI 2XN7A 1R1LI 4AJTA 1ATHA 1B3KA 1DZHL 2B4XI 1QMNA 1BY7A 4RO9A 4C41A 3PB1I 4EB1I 1JRRA 1AS4A 1A7CA 1SNGA 8APIA 2CEOA 2WXZA 1HP7A 2H4QA 2GD4C
chains in the Genus database with same CATH topology
4RSQA 1DVNA 4AU2A 1QLPA 2WXWA 3Q03A 1EZXA 1OPHA 1OC0A 1LK6I 1ATUA 2BEHL 3DY0A 1E03I 3B9FI 3F1SA 1DZGL 1OO8A 3R4LA 1DZHI 2VDYA 3F02A 4ROAA 2OAYA 5CE0A 1C5GA 4R9IA 4G8RA 2D26A 4IF8A 3NE4A 2XN5A 1DB2A 1SR5A 1WZ9A 1KCTA 1C8OA 3CWMA 5CDZA 1D5SA 2XN6A 5EI0A 3NDAA 1JVQI 4AFXA 5CDXA 4AQHA 3F5NA 4DTEA 3NDFA 2HIJI 5HGCA 4DY7C 2WXYC 4Y40A 1ANTI 1AZXI 2ZNHA 1PSIA 1JMOA 2WXZC 1TB6I 3NDDA 1LQ8A 5BRRI 1HLEA 2DUTA 4AU3A 3PZFA 4G8OA 2WY1A 3DRMA 2VH4A 7APIA 2ZV6A 4DY0A 3STOA 2ARRA 3UT3A 2B4XL 3DRUA 1XQJA 1IMVA 1OVAB 2PEFA 2QUGA 2RIWA 2WXXA 3FGQA 3ZHAA 2PEEA 4P0FA 1NQ9I 1E04I 1YXAA 1LJ5A 4ZK3A 9APIA 2VDXA 9PAIA 1XQGA 2R9YA 3CAAA 4IC0A 3VVJA 1IZ2A 2H4RA 4Y3KA 4AU3B 1XU8A 1JJOC 2B5TI 3H5CA 2ANTI 4C49A 1OVAA 2ARQA 2BEHI 3CVMA 1QMBA 1DVMA 1OYHL 1DZGI 1E05I 2WY0C 5C98A 3EOXA 4ROBA 2ACHA 2XN3A 3DLWA 5IO1A 1MTPA 1OVAC 5INWA 2RIVA 4CAAA 4GA7A 1T1FA 4P0OA 4AU4A 3EVJI 4KDSA 1JMJA 3CWLA 4PYWA 3Q02A 3T1PA 1SEKA 1UHGA 2HI9A 4EB1L 1ATTA 1JTIA 2OL2A 2HIJL 1OYHI 4YIAA 3LE2A 2H4PA 1BR8I 2V95A 4ZK0A 3LW2A 4X30A 1M93B 3OZQA 4AJUA 3KCGI 1F0CA 4BB2A 1K9OI 2XN7A 1R1LI 4AJTA 1ATHA 1B3KA 1DZHL 2B4XI 1QMNA 1BY7A 4RO9A 4C41A 3PB1I 4EB1I 1JRRA 1AS4A 1A7CA 1SNGA 8APIA 2CEOA 2WXZA 1HP7A 2H4QA 2GD4C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RSQ A;  1DVN A;  4AU2 A;  1QLP A;  2WXW A;  3Q03 A;  1EZX A;  1OPH A;  1OC0 A;  1LK6 I;  1ATU A;  2BEH L;  3DY0 A;  1E03 I;  3B9F I;  3F1S A;  1DZG L;  1OO8 A;  3R4L A;  1DZH I;  2VDY A;  3F02 A;  4ROA A;  2OAY A;  5CE0 A;  1C5G A;  4R9I A;  4G8R A;  2D26 A;  4IF8 A;  3NE4 A;  2XN5 A;  1DB2 A;  1SR5 A;  1WZ9 A;  1KCT A;  1C8O A;  3CWM A;  5CDZ A;  1D5S A;  2XN6 A;  5EI0 A;  3NDA A;  1JVQ I;  4AFX A;  5CDX A;  4AQH A;  3F5N A;  4DTE A;  3NDF A;  2HIJ I;  5HGC A;  4DY7 C;  2WXY C;  4Y40 A;  1ANT I;  1AZX I;  2ZNH A;  1PSI A;  1JMO A;  2WXZ C;  1TB6 I;  3NDD A;  1LQ8 A;  5BRR I;  1HLE A;  2DUT A;  4AU3 A;  3PZF A;  4G8O A;  2WY1 A;  3DRM A;  2VH4 A;  7API A;  2ZV6 A;  4DY0 A;  3STO A;  2ARR A;  3UT3 A;  2B4X L;  3DRU A;  1XQJ A;  1IMV A;  1OVA B;  2PEF A;  2QUG A;  2RIW A;  2WXX A;  3FGQ A;  3ZHA A;  2PEE A;  4P0F A;  1NQ9 I;  1E04 I;  1YXA A;  1LJ5 A;  4ZK3 A;  9API A;  2VDX A;  9PAI A;  1XQG A;  2R9Y A;  3CAA A;  4IC0 A;  3VVJ A;  1IZ2 A;  2H4R A;  4Y3K A;  4AU3 B;  1XU8 A;  1JJO C;  2B5T I;  3H5C A;  2ANT I;  4C49 A;  1OVA A;  2ARQ A;  2BEH I;  3CVM A;  1QMB A;  1DVM A;  1OYH L;  1DZG I;  1E05 I;  2WY0 C;  5C98 A;  3EOX A;  4ROB A;  2ACH A;  2XN3 A;  3DLW A;  5IO1 A;  1MTP A;  1OVA C;  5INW A;  2RIV A;  4CAA A;  4GA7 A;  1T1F A;  4P0O A;  4AU4 A;  3EVJ I;  4KDS A;  1JMJ A;  3CWL A;  4PYW A;  3Q02 A;  3T1P A;  1SEK A;  1UHG A;  2HI9 A;  4EB1 L;  1ATT A;  1JTI A;  2OL2 A;  2HIJ L;  1OYH I;  4YIA A;  3LE2 A;  2H4P A;  1BR8 I;  2V95 A;  4ZK0 A;  3LW2 A;  4X30 A;  1M93 B;  3OZQ A;  4AJU A;  3KCG I;  1F0C A;  4BB2 A;  1K9O I;  2XN7 A;  1R1L I;  4AJT A;  1ATH A;  1B3K A;  1DZH L;  2B4X I;  1QMN A;  1BY7 A;  4RO9 A;  4C41 A;  3PB1 I;  4EB1 I;  1JRR A;  1AS4 A;  1A7C A;  1SNG A;  8API A;  2CEO A;  2WXZ A;  1HP7 A;  2H4Q A;  2GD4 C; 
#chains in the Genus database with same CATH topology
 4RSQ A;  1DVN A;  4AU2 A;  1QLP A;  2WXW A;  3Q03 A;  1EZX A;  1OPH A;  1OC0 A;  1LK6 I;  1ATU A;  2BEH L;  3DY0 A;  1E03 I;  3B9F I;  3F1S A;  1DZG L;  1OO8 A;  3R4L A;  1DZH I;  2VDY A;  3F02 A;  4ROA A;  2OAY A;  5CE0 A;  1C5G A;  4R9I A;  4G8R A;  2D26 A;  4IF8 A;  3NE4 A;  2XN5 A;  1DB2 A;  1SR5 A;  1WZ9 A;  1KCT A;  1C8O A;  3CWM A;  5CDZ A;  1D5S A;  2XN6 A;  5EI0 A;  3NDA A;  1JVQ I;  4AFX A;  5CDX A;  4AQH A;  3F5N A;  4DTE A;  3NDF A;  2HIJ I;  5HGC A;  4DY7 C;  2WXY C;  4Y40 A;  1ANT I;  1AZX I;  2ZNH A;  1PSI A;  1JMO A;  2WXZ C;  1TB6 I;  3NDD A;  1LQ8 A;  5BRR I;  1HLE A;  2DUT A;  4AU3 A;  3PZF A;  4G8O A;  2WY1 A;  3DRM A;  2VH4 A;  7API A;  2ZV6 A;  4DY0 A;  3STO A;  2ARR A;  3UT3 A;  2B4X L;  3DRU A;  1XQJ A;  1IMV A;  1OVA B;  2PEF A;  2QUG A;  2RIW A;  2WXX A;  3FGQ A;  3ZHA A;  2PEE A;  4P0F A;  1NQ9 I;  1E04 I;  1YXA A;  1LJ5 A;  4ZK3 A;  9API A;  2VDX A;  9PAI A;  1XQG A;  2R9Y A;  3CAA A;  4IC0 A;  3VVJ A;  1IZ2 A;  2H4R A;  4Y3K A;  4AU3 B;  1XU8 A;  1JJO C;  2B5T I;  3H5C A;  2ANT I;  4C49 A;  1OVA A;  2ARQ A;  2BEH I;  3CVM A;  1QMB A;  1DVM A;  1OYH L;  1DZG I;  1E05 I;  2WY0 C;  5C98 A;  3EOX A;  4ROB A;  2ACH A;  2XN3 A;  3DLW A;  5IO1 A;  1MTP A;  1OVA C;  5INW A;  2RIV A;  4CAA A;  4GA7 A;  1T1F A;  4P0O A;  4AU4 A;  3EVJ I;  4KDS A;  1JMJ A;  3CWL A;  4PYW A;  3Q02 A;  3T1P A;  1SEK A;  1UHG A;  2HI9 A;  4EB1 L;  1ATT A;  1JTI A;  2OL2 A;  2HIJ L;  1OYH I;  4YIA A;  3LE2 A;  2H4P A;  1BR8 I;  2V95 A;  4ZK0 A;  3LW2 A;  4X30 A;  1M93 B;  3OZQ A;  4AJU A;  3KCG I;  1F0C A;  4BB2 A;  1K9O I;  2XN7 A;  1R1L I;  4AJT A;  1ATH A;  1B3K A;  1DZH L;  2B4X I;  1QMN A;  1BY7 A;  4RO9 A;  4C41 A;  3PB1 I;  4EB1 I;  1JRR A;  1AS4 A;  1A7C A;  1SNG A;  8API A;  2CEO A;  2WXZ A;  1HP7 A;  2H4Q A;  2GD4 C; 
#chains in the Genus database with same CATH homology
 4RSQ A;  1DVN A;  4AU2 A;  1QLP A;  2WXW A;  3Q03 A;  1EZX A;  1OPH A;  1OC0 A;  1LK6 I;  1ATU A;  2BEH L;  3DY0 A;  1E03 I;  3B9F I;  3F1S A;  1DZG L;  1OO8 A;  3R4L A;  1DZH I;  2VDY A;  3F02 A;  4ROA A;  2OAY A;  5CE0 A;  1C5G A;  4R9I A;  4G8R A;  2D26 A;  4IF8 A;  3NE4 A;  2XN5 A;  1DB2 A;  1SR5 A;  1WZ9 A;  1KCT A;  1C8O A;  3CWM A;  5CDZ A;  1D5S A;  2XN6 A;  5EI0 A;  3NDA A;  1JVQ I;  4AFX A;  5CDX A;  4AQH A;  3F5N A;  4DTE A;  3NDF A;  2HIJ I;  5HGC A;  4DY7 C;  2WXY C;  4Y40 A;  1ANT I;  1AZX I;  2ZNH A;  1PSI A;  1JMO A;  2WXZ C;  1TB6 I;  3NDD A;  1LQ8 A;  5BRR I;  1HLE A;  2DUT A;  4AU3 A;  3PZF A;  4G8O A;  2WY1 A;  3DRM A;  2VH4 A;  7API A;  2ZV6 A;  4DY0 A;  3STO A;  2ARR A;  3UT3 A;  2B4X L;  3DRU A;  1XQJ A;  1IMV A;  1OVA B;  2PEF A;  2QUG A;  2RIW A;  2WXX A;  3FGQ A;  3ZHA A;  2PEE A;  4P0F A;  1NQ9 I;  1E04 I;  1YXA A;  1LJ5 A;  4ZK3 A;  9API A;  2VDX A;  9PAI A;  1XQG A;  2R9Y A;  3CAA A;  4IC0 A;  3VVJ A;  1IZ2 A;  2H4R A;  4Y3K A;  4AU3 B;  1XU8 A;  1JJO C;  2B5T I;  3H5C A;  2ANT I;  4C49 A;  1OVA A;  2ARQ A;  2BEH I;  3CVM A;  1QMB A;  1DVM A;  1OYH L;  1DZG I;  1E05 I;  2WY0 C;  5C98 A;  3EOX A;  4ROB A;  2ACH A;  2XN3 A;  3DLW A;  5IO1 A;  1MTP A;  1OVA C;  5INW A;  2RIV A;  4CAA A;  4GA7 A;  1T1F A;  4P0O A;  4AU4 A;  3EVJ I;  4KDS A;  1JMJ A;  3CWL A;  4PYW A;  3Q02 A;  3T1P A;  1SEK A;  1UHG A;  2HI9 A;  4EB1 L;  1ATT A;  1JTI A;  2OL2 A;  2HIJ L;  1OYH I;  4YIA A;  3LE2 A;  2H4P A;  1BR8 I;  2V95 A;  4ZK0 A;  3LW2 A;  4X30 A;  1M93 B;  3OZQ A;  4AJU A;  3KCG I;  1F0C A;  4BB2 A;  1K9O I;  2XN7 A;  1R1L I;  4AJT A;  1ATH A;  1B3K A;  1DZH L;  2B4X I;  1QMN A;  1BY7 A;  4RO9 A;  4C41 A;  3PB1 I;  4EB1 I;  1JRR A;  1AS4 A;  1A7C A;  1SNG A;  8API A;  2CEO A;  2WXZ A;  1HP7 A;  2H4Q A;  2GD4 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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