5HGCA

A serpin structure
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
378
structure length
373
Chain Sequence
SNAEAMAALKLVPNNADFAFQFFREVTQEAPNKNIFYSPVSISTAFAMLALGARSATQSQILEGLAFNLTEIQEKEIHEGFHNLIHMLNHPEGGVQLNMMNAIFVTAALALLRKFLDDAKALYQLEAFTTDFNKPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKPFEAEHTEEREFFVDAETTVKVPMMYQMGRFDFYFDEELSCTVVRLHYNGSATAFLVLPAKGKMKQLEQTLDKETIQKWSDHLFQRFMNLYFPKFSISGSYEISNTLRKMGIVDVFTNQADLSGITGSPDLKVSKVVHKASLDVDEKGTTAVEIMPISFPPTIEFSHPFLMLIFDRDTNSTLFIGKIVNPTI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Blood clotting
molecule keywords Serpin
publication title A Serpin structure
doi rcsb
source organism Taeniopygia guttata
total genus 115
structure length 373
sequence length 378
ec nomenclature
pdb deposition date 2016-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00079 Serpin Serpin (serine protease inhibitor)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 5hgcA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 5hgcA01
4P0OA 4C41A 2H4QA 2WXWA 2VH4A 2B4XI 1DZHL 7APIA 2V95A 1T1FA 1D5SA 3FGQA 4X30A 2HIJL 3Q02A 2B5TI 1OVAC 2DUTA 2OAYA 3Q03A 1JVQI 1KCTA 2GD4C 2R9YA 4P0FA 4G8RA 1JMOA 1DVMA 1DZGL 1HLEA 3CWMA 3STOA 1IMVA 5EI0A 3B9FI 1JJOC 2WXXA 1XU8A 1EZXA 3R4LA 1OO8A 3EOXA 1A7CA 1QMBA 4RO9A 1ATUA 1ATTA 2OL2A 4AJTA 2B4XL 2D26A 5CE0A 3NDFA 4YIAA 4IF8A 2RIWA 5C98A 2VDXA 2XN5A 4AU3B 4ROAA 1SR5A 4AJUA 2WXZA 1WZ9A 2ARRA 1OVAB 1QMNA 3DRUA 3EVJI 4DY0A 1AS4A 5IO1A 3DRMA 4ZK0A 1LK6I 4ROBA 4EB1I 4GA7A 1DVNA 1YXAA 3ZHAA 2ARQA 2ZNHA 1OC0A 1MTPA 1C8OA 1TB6I 3NDDA 3OZQA 2HI9A 1R1LI 1NQ9I 2QUGA 1AZXI 2VDYA 2RIVA 2ACHA 2WXZC 3VVJA 2BEHI 3CVMA 1BY7A 5CDXA 8APIA 4IC0A 3F1SA 2WXYC 2ZV6A 1QLPA 4G8OA 4Y40A 1DB2A 3NE4A 3CWLA 1PSIA 4AQHA 2XN7A 4AU3A 4EB1L 1F0CA 1JMJA 1OYHI 1E03I 5INWA 1ATHA 1SNGA 3UT3A 4C49A 1UHGA 4KDSA 2WY1A 2H4RA 5HGCA 4AU2A 4DTEA 5CDZA 2H4PA 2PEFA 2ANTI 1B3KA 4AFXA 3H5CA 4R9IA 3KCGI 3CAAA 1LJ5A 9APIA 2WY0C 1K9OI 1E05I 1SEKA 2BEHL 1IZ2A 4CAAA 1OPHA 3PB1I 1ANTI 1DZHI 2XN3A 4Y3KA 1JRRA 1BR8I 1E04I 1XQJA 2HIJI 1XQGA 2XN6A 3LE2A 4AU4A 2CEOA 3DY0A 1OYHL 1DZGI 3LW2A 1C5GA 2PEEA 1OVAA 1LQ8A 4ZK3A 1M93B 3F02A 4BB2A 4RSQA 5BRRI 9PAIA 4DY7C 3PZFA 1HP7A 4PYWA 3T1PA 1JTIA 3DLWA 3NDAA 3F5NA
chains in the Genus database with same CATH superfamily
4P0OA 4C41A 2H4QA 2WXWA 2VH4A 2B4XI 1DZHL 7APIA 2V95A 1T1FA 1D5SA 3FGQA 4X30A 2HIJL 3Q02A 2B5TI 1OVAC 2DUTA 2OAYA 3Q03A 1JVQI 1KCTA 2GD4C 2R9YA 4P0FA 4G8RA 1JMOA 1DVMA 1DZGL 1HLEA 3CWMA 3STOA 1IMVA 5EI0A 3B9FI 1JJOC 2WXXA 1XU8A 1EZXA 3R4LA 1OO8A 3EOXA 1A7CA 1QMBA 4RO9A 1ATUA 1ATTA 2OL2A 4AJTA 2B4XL 2D26A 5CE0A 3NDFA 4YIAA 4IF8A 2RIWA 5C98A 2VDXA 2XN5A 4AU3B 4ROAA 1SR5A 4AJUA 2WXZA 1WZ9A 2ARRA 1OVAB 1QMNA 3DRUA 3EVJI 4DY0A 1AS4A 5IO1A 3DRMA 4ZK0A 1LK6I 4ROBA 4EB1I 4GA7A 1DVNA 1YXAA 3ZHAA 2ARQA 2ZNHA 1OC0A 1MTPA 1C8OA 1TB6I 3NDDA 3OZQA 2HI9A 1R1LI 1NQ9I 2QUGA 1AZXI 2VDYA 2RIVA 2ACHA 2WXZC 3VVJA 2BEHI 3CVMA 1BY7A 5CDXA 8APIA 4IC0A 3F1SA 2WXYC 2ZV6A 1QLPA 4G8OA 4Y40A 1DB2A 3NE4A 3CWLA 1PSIA 4AQHA 2XN7A 4AU3A 4EB1L 1F0CA 1JMJA 1OYHI 1E03I 5INWA 1ATHA 1SNGA 3UT3A 4C49A 1UHGA 4KDSA 2WY1A 2H4RA 5HGCA 4AU2A 4DTEA 5CDZA 2H4PA 2PEFA 2ANTI 1B3KA 4AFXA 3H5CA 4R9IA 3KCGI 3CAAA 1LJ5A 9APIA 2WY0C 1K9OI 1E05I 1SEKA 2BEHL 1IZ2A 4CAAA 1OPHA 3PB1I 1ANTI 1DZHI 2XN3A 4Y3KA 1JRRA 1BR8I 1E04I 1XQJA 2HIJI 1XQGA 2XN6A 3LE2A 4AU4A 2CEOA 3DY0A 1OYHL 1DZGI 3LW2A 1C5GA 2PEEA 1OVAA 1LQ8A 4ZK3A 1M93B 3F02A 4BB2A 4RSQA 5BRRI 9PAIA 4DY7C 3PZFA 1HP7A 4PYWA 3T1PA 1JTIA 3DLWA 3NDAA 3F5NA
chains in the Genus database with same CATH topology
4P0OA 4C41A 2H4QA 2WXWA 2VH4A 2B4XI 1DZHL 7APIA 2V95A 1T1FA 1D5SA 3FGQA 4X30A 2HIJL 3Q02A 2B5TI 1OVAC 2DUTA 2OAYA 3Q03A 1JVQI 1KCTA 2GD4C 2R9YA 4P0FA 4G8RA 1JMOA 1DVMA 1DZGL 1HLEA 3CWMA 3STOA 1IMVA 5EI0A 3B9FI 1JJOC 2WXXA 1XU8A 1EZXA 3R4LA 1OO8A 3EOXA 1A7CA 1QMBA 4RO9A 1ATUA 1ATTA 2OL2A 4AJTA 2B4XL 2D26A 5CE0A 3NDFA 4YIAA 4IF8A 2RIWA 5C98A 2VDXA 2XN5A 4AU3B 4ROAA 1SR5A 4AJUA 2WXZA 1WZ9A 2ARRA 1OVAB 1QMNA 3DRUA 3EVJI 4DY0A 1AS4A 5IO1A 3DRMA 4ZK0A 1LK6I 4ROBA 4EB1I 4GA7A 1DVNA 1YXAA 3ZHAA 2ARQA 2ZNHA 1OC0A 1MTPA 1C8OA 1TB6I 3NDDA 3OZQA 2HI9A 1R1LI 1NQ9I 2QUGA 1AZXI 2VDYA 2RIVA 2ACHA 2WXZC 3VVJA 2BEHI 3CVMA 1BY7A 5CDXA 8APIA 4IC0A 3F1SA 2WXYC 2ZV6A 1QLPA 4G8OA 4Y40A 1DB2A 3NE4A 3CWLA 1PSIA 4AQHA 2XN7A 4AU3A 4EB1L 1F0CA 1JMJA 1OYHI 1E03I 5INWA 1ATHA 1SNGA 3UT3A 4C49A 1UHGA 4KDSA 2WY1A 2H4RA 5HGCA 4AU2A 4DTEA 5CDZA 2H4PA 2PEFA 2ANTI 1B3KA 4AFXA 3H5CA 4R9IA 3KCGI 3CAAA 1LJ5A 9APIA 2WY0C 1K9OI 1E05I 1SEKA 2BEHL 1IZ2A 4CAAA 1OPHA 3PB1I 1ANTI 1DZHI 2XN3A 4Y3KA 1JRRA 1BR8I 1E04I 1XQJA 2HIJI 1XQGA 2XN6A 3LE2A 4AU4A 2CEOA 3DY0A 1OYHL 1DZGI 3LW2A 1C5GA 2PEEA 1OVAA 1LQ8A 4ZK3A 1M93B 3F02A 4BB2A 4RSQA 5BRRI 9PAIA 4DY7C 3PZFA 1HP7A 4PYWA 3T1PA 1JTIA 3DLWA 3NDAA 3F5NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P0O A;  4C41 A;  2H4Q A;  2WXW A;  2VH4 A;  2B4X I;  1DZH L;  7API A;  2V95 A;  1T1F A;  1D5S A;  3FGQ A;  4X30 A;  2HIJ L;  3Q02 A;  2B5T I;  1OVA C;  2DUT A;  2OAY A;  3Q03 A;  1JVQ I;  1KCT A;  2GD4 C;  2R9Y A;  4P0F A;  4G8R A;  1JMO A;  1DVM A;  1DZG L;  1HLE A;  3CWM A;  3STO A;  1IMV A;  5EI0 A;  3B9F I;  1JJO C;  2WXX A;  1XU8 A;  1EZX A;  3R4L A;  1OO8 A;  3EOX A;  1A7C A;  1QMB A;  4RO9 A;  1ATU A;  1ATT A;  2OL2 A;  4AJT A;  2B4X L;  2D26 A;  5CE0 A;  3NDF A;  4YIA A;  4IF8 A;  2RIW A;  5C98 A;  2VDX A;  2XN5 A;  4AU3 B;  4ROA A;  1SR5 A;  4AJU A;  2WXZ A;  1WZ9 A;  2ARR A;  1OVA B;  1QMN A;  3DRU A;  3EVJ I;  4DY0 A;  1AS4 A;  5IO1 A;  3DRM A;  4ZK0 A;  1LK6 I;  4ROB A;  4EB1 I;  4GA7 A;  1DVN A;  1YXA A;  3ZHA A;  2ARQ A;  2ZNH A;  1OC0 A;  1MTP A;  1C8O A;  1TB6 I;  3NDD A;  3OZQ A;  2HI9 A;  1R1L I;  1NQ9 I;  2QUG A;  1AZX I;  2VDY A;  2RIV A;  2ACH A;  2WXZ C;  3VVJ A;  2BEH I;  3CVM A;  1BY7 A;  5CDX A;  8API A;  4IC0 A;  3F1S A;  2WXY C;  2ZV6 A;  1QLP A;  4G8O A;  4Y40 A;  1DB2 A;  3NE4 A;  3CWL A;  1PSI A;  4AQH A;  2XN7 A;  4AU3 A;  4EB1 L;  1F0C A;  1JMJ A;  1OYH I;  1E03 I;  5INW A;  1ATH A;  1SNG A;  3UT3 A;  4C49 A;  1UHG A;  4KDS A;  2WY1 A;  2H4R A;  5HGC A;  4AU2 A;  4DTE A;  5CDZ A;  2H4P A;  2PEF A;  2ANT I;  1B3K A;  4AFX A;  3H5C A;  4R9I A;  3KCG I;  3CAA A;  1LJ5 A;  9API A;  2WY0 C;  1K9O I;  1E05 I;  1SEK A;  2BEH L;  1IZ2 A;  4CAA A;  1OPH A;  3PB1 I;  1ANT I;  1DZH I;  2XN3 A;  4Y3K A;  1JRR A;  1BR8 I;  1E04 I;  1XQJ A;  2HIJ I;  1XQG A;  2XN6 A;  3LE2 A;  4AU4 A;  2CEO A;  3DY0 A;  1OYH L;  1DZG I;  3LW2 A;  1C5G A;  2PEE A;  1OVA A;  1LQ8 A;  4ZK3 A;  1M93 B;  3F02 A;  4BB2 A;  4RSQ A;  5BRR I;  9PAI A;  4DY7 C;  3PZF A;  1HP7 A;  4PYW A;  3T1P A;  1JTI A;  3DLW A;  3NDA A;  3F5N A; 
#chains in the Genus database with same CATH topology
 4P0O A;  4C41 A;  2H4Q A;  2WXW A;  2VH4 A;  2B4X I;  1DZH L;  7API A;  2V95 A;  1T1F A;  1D5S A;  3FGQ A;  4X30 A;  2HIJ L;  3Q02 A;  2B5T I;  1OVA C;  2DUT A;  2OAY A;  3Q03 A;  1JVQ I;  1KCT A;  2GD4 C;  2R9Y A;  4P0F A;  4G8R A;  1JMO A;  1DVM A;  1DZG L;  1HLE A;  3CWM A;  3STO A;  1IMV A;  5EI0 A;  3B9F I;  1JJO C;  2WXX A;  1XU8 A;  1EZX A;  3R4L A;  1OO8 A;  3EOX A;  1A7C A;  1QMB A;  4RO9 A;  1ATU A;  1ATT A;  2OL2 A;  4AJT A;  2B4X L;  2D26 A;  5CE0 A;  3NDF A;  4YIA A;  4IF8 A;  2RIW A;  5C98 A;  2VDX A;  2XN5 A;  4AU3 B;  4ROA A;  1SR5 A;  4AJU A;  2WXZ A;  1WZ9 A;  2ARR A;  1OVA B;  1QMN A;  3DRU A;  3EVJ I;  4DY0 A;  1AS4 A;  5IO1 A;  3DRM A;  4ZK0 A;  1LK6 I;  4ROB A;  4EB1 I;  4GA7 A;  1DVN A;  1YXA A;  3ZHA A;  2ARQ A;  2ZNH A;  1OC0 A;  1MTP A;  1C8O A;  1TB6 I;  3NDD A;  3OZQ A;  2HI9 A;  1R1L I;  1NQ9 I;  2QUG A;  1AZX I;  2VDY A;  2RIV A;  2ACH A;  2WXZ C;  3VVJ A;  2BEH I;  3CVM A;  1BY7 A;  5CDX A;  8API A;  4IC0 A;  3F1S A;  2WXY C;  2ZV6 A;  1QLP A;  4G8O A;  4Y40 A;  1DB2 A;  3NE4 A;  3CWL A;  1PSI A;  4AQH A;  2XN7 A;  4AU3 A;  4EB1 L;  1F0C A;  1JMJ A;  1OYH I;  1E03 I;  5INW A;  1ATH A;  1SNG A;  3UT3 A;  4C49 A;  1UHG A;  4KDS A;  2WY1 A;  2H4R A;  5HGC A;  4AU2 A;  4DTE A;  5CDZ A;  2H4P A;  2PEF A;  2ANT I;  1B3K A;  4AFX A;  3H5C A;  4R9I A;  3KCG I;  3CAA A;  1LJ5 A;  9API A;  2WY0 C;  1K9O I;  1E05 I;  1SEK A;  2BEH L;  1IZ2 A;  4CAA A;  1OPH A;  3PB1 I;  1ANT I;  1DZH I;  2XN3 A;  4Y3K A;  1JRR A;  1BR8 I;  1E04 I;  1XQJ A;  2HIJ I;  1XQG A;  2XN6 A;  3LE2 A;  4AU4 A;  2CEO A;  3DY0 A;  1OYH L;  1DZG I;  3LW2 A;  1C5G A;  2PEE A;  1OVA A;  1LQ8 A;  4ZK3 A;  1M93 B;  3F02 A;  4BB2 A;  4RSQ A;  5BRR I;  9PAI A;  4DY7 C;  3PZF A;  1HP7 A;  4PYW A;  3T1P A;  1JTI A;  3DLW A;  3NDA A;  3F5N A; 
#chains in the Genus database with same CATH homology
 4P0O A;  4C41 A;  2H4Q A;  2WXW A;  2VH4 A;  2B4X I;  1DZH L;  7API A;  2V95 A;  1T1F A;  1D5S A;  3FGQ A;  4X30 A;  2HIJ L;  3Q02 A;  2B5T I;  1OVA C;  2DUT A;  2OAY A;  3Q03 A;  1JVQ I;  1KCT A;  2GD4 C;  2R9Y A;  4P0F A;  4G8R A;  1JMO A;  1DVM A;  1DZG L;  1HLE A;  3CWM A;  3STO A;  1IMV A;  5EI0 A;  3B9F I;  1JJO C;  2WXX A;  1XU8 A;  1EZX A;  3R4L A;  1OO8 A;  3EOX A;  1A7C A;  1QMB A;  4RO9 A;  1ATU A;  1ATT A;  2OL2 A;  4AJT A;  2B4X L;  2D26 A;  5CE0 A;  3NDF A;  4YIA A;  4IF8 A;  2RIW A;  5C98 A;  2VDX A;  2XN5 A;  4AU3 B;  4ROA A;  1SR5 A;  4AJU A;  2WXZ A;  1WZ9 A;  2ARR A;  1OVA B;  1QMN A;  3DRU A;  3EVJ I;  4DY0 A;  1AS4 A;  5IO1 A;  3DRM A;  4ZK0 A;  1LK6 I;  4ROB A;  4EB1 I;  4GA7 A;  1DVN A;  1YXA A;  3ZHA A;  2ARQ A;  2ZNH A;  1OC0 A;  1MTP A;  1C8O A;  1TB6 I;  3NDD A;  3OZQ A;  2HI9 A;  1R1L I;  1NQ9 I;  2QUG A;  1AZX I;  2VDY A;  2RIV A;  2ACH A;  2WXZ C;  3VVJ A;  2BEH I;  3CVM A;  1BY7 A;  5CDX A;  8API A;  4IC0 A;  3F1S A;  2WXY C;  2ZV6 A;  1QLP A;  4G8O A;  4Y40 A;  1DB2 A;  3NE4 A;  3CWL A;  1PSI A;  4AQH A;  2XN7 A;  4AU3 A;  4EB1 L;  1F0C A;  1JMJ A;  1OYH I;  1E03 I;  5INW A;  1ATH A;  1SNG A;  3UT3 A;  4C49 A;  1UHG A;  4KDS A;  2WY1 A;  2H4R A;  5HGC A;  4AU2 A;  4DTE A;  5CDZ A;  2H4P A;  2PEF A;  2ANT I;  1B3K A;  4AFX A;  3H5C A;  4R9I A;  3KCG I;  3CAA A;  1LJ5 A;  9API A;  2WY0 C;  1K9O I;  1E05 I;  1SEK A;  2BEH L;  1IZ2 A;  4CAA A;  1OPH A;  3PB1 I;  1ANT I;  1DZH I;  2XN3 A;  4Y3K A;  1JRR A;  1BR8 I;  1E04 I;  1XQJ A;  2HIJ I;  1XQG A;  2XN6 A;  3LE2 A;  4AU4 A;  2CEO A;  3DY0 A;  1OYH L;  1DZG I;  3LW2 A;  1C5G A;  2PEE A;  1OVA A;  1LQ8 A;  4ZK3 A;  1M93 B;  3F02 A;  4BB2 A;  4RSQ A;  5BRR I;  9PAI A;  4DY7 C;  3PZF A;  1HP7 A;  4PYW A;  3T1P A;  1JTI A;  3DLW A;  3NDA A;  3F5N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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