5INWA

Structure of reaction loop cleaved lamprey angiotensinogen
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
345
structure length
335
Chain Sequence
KKSKTQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASALGVVTAGANGSTRAELDTALGFKSMKYFARLNGALYKRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFKSNVRSVDFGDSKNAVELMNAYIEKVTSKKFPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPDLTKNVRFWVNSSYSMMVPTMHQRAKLSYTQDRKLRSTVVKLPYEGGASMLVIVPHRTEDLPKVEESVSQEQLEEWLSLLGPSNHYVQLSLPKFKISVSYDLKAYLSAMGMSSMFSYGADLSRITGMQKLHVDKITHKSVLHVNEEGTEAKAETVVGIMA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
pubmed doi rcsb
molecule tags Hormone
source organism Lampetra fluviatilis
molecule keywords Putative angiotensinogen
total genus 88
structure length 335
sequence length 345
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-03-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.39.10 Mainly Beta Roll Alpha-1-antitrypsin; domain 1 Alpha-1-antitrypsin, domain 1 5inwA02
3.30.497.10 Alpha Beta 2-Layer Sandwich Antithrombin; Chain I, domain 2 Antithrombin, subunit I, domain 2 5inwA01
1HP7A 4IC0A 1OO8A 1A7CA 1JJOC 3EVJI 3Q02A 2XN3A 4AU4A 2B5TI 3LE2A 2H4PA 4C49A 2QUGA 1SNGA 2ANTI 3FGQA 4AU3A 3NE4A 9APIA 5INWA 1TB6I 2WXZC 1XU8A 2B4XI 2R9YA 1JTIA 4P0OA 1QLPA 1C5GA 2ACHA 3NDAA 9PAIA 5IO1A 1QMBA 5HGCA 1DVNA 1HLEA 1XQGA 2VDXA 2WXZA 2B4XL 2WXWA 2ZV6A 1JMOA 3CAAA 4RSQA 3UT3A 1LJ5A 3PB1I 4AQHA 1DVMA 2ARQA 2DUTA 2XN5A 3R4LA 4IF8A 2RIVA 1UHGA 2ZNHA 1DZHI 2HIJI 2VDYA 1YXAA 2XN6A 3B9FI 4AU2A 1PSIA 5CDXA 3NDFA 2PEFA 3F02A 3STOA 1OVAB 4C41A 4ZK3A 1ATUA 2WY1A 2PEEA 1DZHL 1T1FA 2HIJL 1R1LI 4ZK0A 2OAYA 2WXYC 1E03I 1E05I 1JMJA 3OZQA 4AJUA 3VVJA 1DB2A 3KCGI 1OVAC 3F5NA 3LW2A 4KDSA 2WY0C 1NQ9I 2XN7A 5CE0A 1LQ8A 1IMVA 1SEKA 3DRMA 3CVMA 3H5CA 4Y40A 2RIWA 2ARRA 3PZFA 3CWLA 3DLWA 4P0FA 1EZXA 3ZHAA 1KCTA 4BB2A 1OVAA 1JRRA 3T1PA 7APIA 2GD4C 1LK6I 4CAAA 5CDZA 2H4RA 2WXXA 4GA7A 1QMNA 4AFXA 1DZGI 2HI9A 1OC0A 1WZ9A 4DY0A 1C8OA 3CWMA 2VH4A 4G8OA 1ATHA 1ATTA 2D26A 4Y3KA 2CEOA 3DY0A 2OL2A 2BEHI 1MTPA 1DZGL 4ROAA 1E04I 1ANTI 1SR5A 1AZXI 4AU3B 1K9OI 2H4QA 3EOXA 4DY7C 1D5SA 4G8RA 4X30A 1AS4A 1F0CA 1OYHI 1M93B 2V95A 4EB1I 4RO9A 3NDDA 3Q03A 1BR8I 1BY7A 1XQJA 4AJTA 2BEHL 1JVQI 4DTEA 8APIA 4PYWA 3DRUA 1OPHA 1B3KA 3F1SA 5BRRI 1OYHL 4ROBA 5EI0A 1IZ2A 4R9IA 4YIAA 5C98A 4EB1L
chains in the Genus database with same CATH superfamily
1HP7A 4IC0A 1OO8A 1A7CA 1JJOC 3EVJI 3Q02A 2XN3A 4AU4A 2B5TI 3LE2A 2H4PA 4C49A 2QUGA 1SNGA 2ANTI 3FGQA 4AU3A 3NE4A 9APIA 5INWA 1TB6I 2WXZC 1XU8A 2B4XI 2R9YA 1JTIA 4P0OA 1QLPA 1C5GA 2ACHA 3NDAA 9PAIA 5IO1A 1QMBA 5HGCA 1DVNA 1HLEA 1XQGA 2VDXA 2WXZA 2B4XL 2WXWA 2ZV6A 1JMOA 3CAAA 4RSQA 3UT3A 1LJ5A 3PB1I 4AQHA 1DVMA 2ARQA 2DUTA 2XN5A 3R4LA 4IF8A 2RIVA 1UHGA 2ZNHA 1DZHI 2HIJI 2VDYA 1YXAA 2XN6A 3B9FI 4AU2A 1PSIA 5CDXA 3NDFA 2PEFA 3F02A 3STOA 1OVAB 4C41A 4ZK3A 1ATUA 2WY1A 2PEEA 1DZHL 1T1FA 2HIJL 1R1LI 4ZK0A 2OAYA 2WXYC 1E03I 1E05I 1JMJA 3OZQA 4AJUA 3VVJA 1DB2A 3KCGI 1OVAC 3F5NA 3LW2A 4KDSA 2WY0C 1NQ9I 2XN7A 5CE0A 1LQ8A 1IMVA 1SEKA 3DRMA 3CVMA 3H5CA 4Y40A 2RIWA 2ARRA 3PZFA 3CWLA 3DLWA 4P0FA 1EZXA 3ZHAA 1KCTA 4BB2A 1OVAA 1JRRA 3T1PA 7APIA 2GD4C 1LK6I 4CAAA 5CDZA 2H4RA 2WXXA 4GA7A 1QMNA 4AFXA 1DZGI 2HI9A 1OC0A 1WZ9A 4DY0A 1C8OA 3CWMA 2VH4A 4G8OA 1ATHA 1ATTA 2D26A 4Y3KA 2CEOA 3DY0A 2OL2A 2BEHI 1MTPA 1DZGL 4ROAA 1E04I 1ANTI 1SR5A 1AZXI 4AU3B 1K9OI 2H4QA 3EOXA 4DY7C 1D5SA 4G8RA 4X30A 1AS4A 1F0CA 1OYHI 1M93B 2V95A 4EB1I 4RO9A 3NDDA 3Q03A 1BR8I 1BY7A 1XQJA 4AJTA 2BEHL 1JVQI 4DTEA 8APIA 4PYWA 3DRUA 1OPHA 1B3KA 3F1SA 5BRRI 1OYHL 4ROBA 5EI0A 1IZ2A 4R9IA 4YIAA 5C98A 4EB1L
chains in the Genus database with same CATH topology
1HP7A 4IC0A 1OO8A 1A7CA 1JJOC 3EVJI 3Q02A 2XN3A 4AU4A 2B5TI 3LE2A 2H4PA 4C49A 2QUGA 1SNGA 2ANTI 3FGQA 4AU3A 3NE4A 9APIA 5INWA 1TB6I 2WXZC 1XU8A 2B4XI 2R9YA 1JTIA 4P0OA 1QLPA 1C5GA 2ACHA 3NDAA 9PAIA 5IO1A 1QMBA 5HGCA 1DVNA 1HLEA 1XQGA 2VDXA 2WXZA 2B4XL 2WXWA 2ZV6A 1JMOA 3CAAA 4RSQA 3UT3A 1LJ5A 3PB1I 4AQHA 1DVMA 2ARQA 2DUTA 2XN5A 3R4LA 4IF8A 2RIVA 1UHGA 2ZNHA 1DZHI 2HIJI 2VDYA 1YXAA 2XN6A 3B9FI 4AU2A 1PSIA 5CDXA 3NDFA 2PEFA 3F02A 3STOA 1OVAB 4C41A 4ZK3A 1ATUA 2WY1A 2PEEA 1DZHL 1T1FA 2HIJL 1R1LI 4ZK0A 2OAYA 2WXYC 1E03I 1E05I 1JMJA 3OZQA 4AJUA 3VVJA 1DB2A 3KCGI 1OVAC 3F5NA 3LW2A 4KDSA 2WY0C 1NQ9I 2XN7A 5CE0A 1LQ8A 1IMVA 1SEKA 3DRMA 3CVMA 3H5CA 4Y40A 2RIWA 2ARRA 3PZFA 3CWLA 3DLWA 4P0FA 1EZXA 3ZHAA 1KCTA 4BB2A 1OVAA 1JRRA 3T1PA 7APIA 2GD4C 1LK6I 4CAAA 5CDZA 2H4RA 2WXXA 4GA7A 1QMNA 4AFXA 1DZGI 2HI9A 1OC0A 1WZ9A 4DY0A 1C8OA 3CWMA 2VH4A 4G8OA 1ATHA 1ATTA 2D26A 4Y3KA 2CEOA 3DY0A 2OL2A 2BEHI 1MTPA 1DZGL 4ROAA 1E04I 1ANTI 1SR5A 1AZXI 4AU3B 1K9OI 2H4QA 3EOXA 4DY7C 1D5SA 4G8RA 4X30A 1AS4A 1F0CA 1OYHI 1M93B 2V95A 4EB1I 4RO9A 3NDDA 3Q03A 1BR8I 1BY7A 1XQJA 4AJTA 2BEHL 1JVQI 4DTEA 8APIA 4PYWA 3DRUA 1OPHA 1B3KA 3F1SA 5BRRI 1OYHL 4ROBA 5EI0A 1IZ2A 4R9IA 4YIAA 5C98A 4EB1L
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HP7 A;  4IC0 A;  1OO8 A;  1A7C A;  1JJO C;  3EVJ I;  3Q02 A;  2XN3 A;  4AU4 A;  2B5T I;  3LE2 A;  2H4P A;  4C49 A;  2QUG A;  1SNG A;  2ANT I;  3FGQ A;  4AU3 A;  3NE4 A;  9API A;  5INW A;  1TB6 I;  2WXZ C;  1XU8 A;  2B4X I;  2R9Y A;  1JTI A;  4P0O A;  1QLP A;  1C5G A;  2ACH A;  3NDA A;  9PAI A;  5IO1 A;  1QMB A;  5HGC A;  1DVN A;  1HLE A;  1XQG A;  2VDX A;  2WXZ A;  2B4X L;  2WXW A;  2ZV6 A;  1JMO A;  3CAA A;  4RSQ A;  3UT3 A;  1LJ5 A;  3PB1 I;  4AQH A;  1DVM A;  2ARQ A;  2DUT A;  2XN5 A;  3R4L A;  4IF8 A;  2RIV A;  1UHG A;  2ZNH A;  1DZH I;  2HIJ I;  2VDY A;  1YXA A;  2XN6 A;  3B9F I;  4AU2 A;  1PSI A;  5CDX A;  3NDF A;  2PEF A;  3F02 A;  3STO A;  1OVA B;  4C41 A;  4ZK3 A;  1ATU A;  2WY1 A;  2PEE A;  1DZH L;  1T1F A;  2HIJ L;  1R1L I;  4ZK0 A;  2OAY A;  2WXY C;  1E03 I;  1E05 I;  1JMJ A;  3OZQ A;  4AJU A;  3VVJ A;  1DB2 A;  3KCG I;  1OVA C;  3F5N A;  3LW2 A;  4KDS A;  2WY0 C;  1NQ9 I;  2XN7 A;  5CE0 A;  1LQ8 A;  1IMV A;  1SEK A;  3DRM A;  3CVM A;  3H5C A;  4Y40 A;  2RIW A;  2ARR A;  3PZF A;  3CWL A;  3DLW A;  4P0F A;  1EZX A;  3ZHA A;  1KCT A;  4BB2 A;  1OVA A;  1JRR A;  3T1P A;  7API A;  2GD4 C;  1LK6 I;  4CAA A;  5CDZ A;  2H4R A;  2WXX A;  4GA7 A;  1QMN A;  4AFX A;  1DZG I;  2HI9 A;  1OC0 A;  1WZ9 A;  4DY0 A;  1C8O A;  3CWM A;  2VH4 A;  4G8O A;  1ATH A;  1ATT A;  2D26 A;  4Y3K A;  2CEO A;  3DY0 A;  2OL2 A;  2BEH I;  1MTP A;  1DZG L;  4ROA A;  1E04 I;  1ANT I;  1SR5 A;  1AZX I;  4AU3 B;  1K9O I;  2H4Q A;  3EOX A;  4DY7 C;  1D5S A;  4G8R A;  4X30 A;  1AS4 A;  1F0C A;  1OYH I;  1M93 B;  2V95 A;  4EB1 I;  4RO9 A;  3NDD A;  3Q03 A;  1BR8 I;  1BY7 A;  1XQJ A;  4AJT A;  2BEH L;  1JVQ I;  4DTE A;  8API A;  4PYW A;  3DRU A;  1OPH A;  1B3K A;  3F1S A;  5BRR I;  1OYH L;  4ROB A;  5EI0 A;  1IZ2 A;  4R9I A;  4YIA A;  5C98 A;  4EB1 L; 
#chains in the Genus database with same CATH topology
 1HP7 A;  4IC0 A;  1OO8 A;  1A7C A;  1JJO C;  3EVJ I;  3Q02 A;  2XN3 A;  4AU4 A;  2B5T I;  3LE2 A;  2H4P A;  4C49 A;  2QUG A;  1SNG A;  2ANT I;  3FGQ A;  4AU3 A;  3NE4 A;  9API A;  5INW A;  1TB6 I;  2WXZ C;  1XU8 A;  2B4X I;  2R9Y A;  1JTI A;  4P0O A;  1QLP A;  1C5G A;  2ACH A;  3NDA A;  9PAI A;  5IO1 A;  1QMB A;  5HGC A;  1DVN A;  1HLE A;  1XQG A;  2VDX A;  2WXZ A;  2B4X L;  2WXW A;  2ZV6 A;  1JMO A;  3CAA A;  4RSQ A;  3UT3 A;  1LJ5 A;  3PB1 I;  4AQH A;  1DVM A;  2ARQ A;  2DUT A;  2XN5 A;  3R4L A;  4IF8 A;  2RIV A;  1UHG A;  2ZNH A;  1DZH I;  2HIJ I;  2VDY A;  1YXA A;  2XN6 A;  3B9F I;  4AU2 A;  1PSI A;  5CDX A;  3NDF A;  2PEF A;  3F02 A;  3STO A;  1OVA B;  4C41 A;  4ZK3 A;  1ATU A;  2WY1 A;  2PEE A;  1DZH L;  1T1F A;  2HIJ L;  1R1L I;  4ZK0 A;  2OAY A;  2WXY C;  1E03 I;  1E05 I;  1JMJ A;  3OZQ A;  4AJU A;  3VVJ A;  1DB2 A;  3KCG I;  1OVA C;  3F5N A;  3LW2 A;  4KDS A;  2WY0 C;  1NQ9 I;  2XN7 A;  5CE0 A;  1LQ8 A;  1IMV A;  1SEK A;  3DRM A;  3CVM A;  3H5C A;  4Y40 A;  2RIW A;  2ARR A;  3PZF A;  3CWL A;  3DLW A;  4P0F A;  1EZX A;  3ZHA A;  1KCT A;  4BB2 A;  1OVA A;  1JRR A;  3T1P A;  7API A;  2GD4 C;  1LK6 I;  4CAA A;  5CDZ A;  2H4R A;  2WXX A;  4GA7 A;  1QMN A;  4AFX A;  1DZG I;  2HI9 A;  1OC0 A;  1WZ9 A;  4DY0 A;  1C8O A;  3CWM A;  2VH4 A;  4G8O A;  1ATH A;  1ATT A;  2D26 A;  4Y3K A;  2CEO A;  3DY0 A;  2OL2 A;  2BEH I;  1MTP A;  1DZG L;  4ROA A;  1E04 I;  1ANT I;  1SR5 A;  1AZX I;  4AU3 B;  1K9O I;  2H4Q A;  3EOX A;  4DY7 C;  1D5S A;  4G8R A;  4X30 A;  1AS4 A;  1F0C A;  1OYH I;  1M93 B;  2V95 A;  4EB1 I;  4RO9 A;  3NDD A;  3Q03 A;  1BR8 I;  1BY7 A;  1XQJ A;  4AJT A;  2BEH L;  1JVQ I;  4DTE A;  8API A;  4PYW A;  3DRU A;  1OPH A;  1B3K A;  3F1S A;  5BRR I;  1OYH L;  4ROB A;  5EI0 A;  1IZ2 A;  4R9I A;  4YIA A;  5C98 A;  4EB1 L; 
#chains in the Genus database with same CATH homology
 1HP7 A;  4IC0 A;  1OO8 A;  1A7C A;  1JJO C;  3EVJ I;  3Q02 A;  2XN3 A;  4AU4 A;  2B5T I;  3LE2 A;  2H4P A;  4C49 A;  2QUG A;  1SNG A;  2ANT I;  3FGQ A;  4AU3 A;  3NE4 A;  9API A;  5INW A;  1TB6 I;  2WXZ C;  1XU8 A;  2B4X I;  2R9Y A;  1JTI A;  4P0O A;  1QLP A;  1C5G A;  2ACH A;  3NDA A;  9PAI A;  5IO1 A;  1QMB A;  5HGC A;  1DVN A;  1HLE A;  1XQG A;  2VDX A;  2WXZ A;  2B4X L;  2WXW A;  2ZV6 A;  1JMO A;  3CAA A;  4RSQ A;  3UT3 A;  1LJ5 A;  3PB1 I;  4AQH A;  1DVM A;  2ARQ A;  2DUT A;  2XN5 A;  3R4L A;  4IF8 A;  2RIV A;  1UHG A;  2ZNH A;  1DZH I;  2HIJ I;  2VDY A;  1YXA A;  2XN6 A;  3B9F I;  4AU2 A;  1PSI A;  5CDX A;  3NDF A;  2PEF A;  3F02 A;  3STO A;  1OVA B;  4C41 A;  4ZK3 A;  1ATU A;  2WY1 A;  2PEE A;  1DZH L;  1T1F A;  2HIJ L;  1R1L I;  4ZK0 A;  2OAY A;  2WXY C;  1E03 I;  1E05 I;  1JMJ A;  3OZQ A;  4AJU A;  3VVJ A;  1DB2 A;  3KCG I;  1OVA C;  3F5N A;  3LW2 A;  4KDS A;  2WY0 C;  1NQ9 I;  2XN7 A;  5CE0 A;  1LQ8 A;  1IMV A;  1SEK A;  3DRM A;  3CVM A;  3H5C A;  4Y40 A;  2RIW A;  2ARR A;  3PZF A;  3CWL A;  3DLW A;  4P0F A;  1EZX A;  3ZHA A;  1KCT A;  4BB2 A;  1OVA A;  1JRR A;  3T1P A;  7API A;  2GD4 C;  1LK6 I;  4CAA A;  5CDZ A;  2H4R A;  2WXX A;  4GA7 A;  1QMN A;  4AFX A;  1DZG I;  2HI9 A;  1OC0 A;  1WZ9 A;  4DY0 A;  1C8O A;  3CWM A;  2VH4 A;  4G8O A;  1ATH A;  1ATT A;  2D26 A;  4Y3K A;  2CEO A;  3DY0 A;  2OL2 A;  2BEH I;  1MTP A;  1DZG L;  4ROA A;  1E04 I;  1ANT I;  1SR5 A;  1AZX I;  4AU3 B;  1K9O I;  2H4Q A;  3EOX A;  4DY7 C;  1D5S A;  4G8R A;  4X30 A;  1AS4 A;  1F0C A;  1OYH I;  1M93 B;  2V95 A;  4EB1 I;  4RO9 A;  3NDD A;  3Q03 A;  1BR8 I;  1BY7 A;  1XQJ A;  4AJT A;  2BEH L;  1JVQ I;  4DTE A;  8API A;  4PYW A;  3DRU A;  1OPH A;  1B3K A;  3F1S A;  5BRR I;  1OYH L;  4ROB A;  5EI0 A;  1IZ2 A;  4R9I A;  4YIA A;  5C98 A;  4EB1 L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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