2KXRA

Zo1 zu5 domain mc/aa mutation
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
118
structure length
118
Chain Sequence
TVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPLVAAGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANCVSVLIDHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Tight junction protein ZO-1
total genus 8
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2010-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00791 ZU5 ZU5 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.220.30 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Chondroitinase Ac; Chain A, domain 3 2kxrA01
3KBUC 2KXRA 4D8OA 3F59A 3KBTC 2KXSA 3UD2A 3UD1A
chains in the Genus database with same CATH superfamily
1RWGA 1RWAA 3QR8A 1HMWA 2BRWA 4DLOA 2WDAA 1N7PA 4D6GA 2E24A 1HN0A 1OJOA 4D71A 1RWHA 2WMIB 1X1HA 2WMFA 1HM3A 1LOHA 3F59A 1X1JA 4D6EA 4D6JA 2WCOA 2WMKA 4D6HA 1N7RA 3UD1A 3U7VA 2Q1FA 3KBUC 4DLQA 2WMGA 2KXRA 4D6CA 1RWFA 2BRVX 4D8OA 1CB8A 1LXKA 1N7QA 4D1JA 1F1SA 1EGUA 1I8QA 1HMUA 1C82A 1N7OA 1X1IA 2KXSA 1RWCA 1OJNA 2WMIA 3PQIA 2E22A 4D6DA 4D6IA 1W3YA 1F9GA 4D6FA 4D72A 1J0NA 2X03A 1HM2A 1RW9A 2WMHA 2BRPA 1OJMA 1N7NA 1OJPA 1LXMA 2WMJA 3KBTC 4D1IA 1J0MA 3UD2A
chains in the Genus database with same CATH topology
3KBUC 3QR8A 4DLOA 2KXRA 4DLQA 4D8OA 3F59A 3KBTC 2KXSA 3UD2A 3UD1A 3PQIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KBU C;  2KXR A;  4D8O A;  3F59 A;  3KBT C;  2KXS A;  3UD2 A;  3UD1 A; 
#chains in the Genus database with same CATH topology
 1RWG A;  1RWA A;  3QR8 A;  1HMW A;  2BRW A;  4DLO A;  2WDA A;  1N7P A;  4D6G A;  2E24 A;  1HN0 A;  1OJO A;  4D71 A;  1RWH A;  2WMI B;  1X1H A;  2WMF A;  1HM3 A;  1LOH A;  3F59 A;  1X1J A;  4D6E A;  4D6J A;  2WCO A;  2WMK A;  4D6H A;  1N7R A;  3UD1 A;  3U7V A;  2Q1F A;  3KBU C;  4DLQ A;  2WMG A;  2KXR A;  4D6C A;  1RWF A;  2BRV X;  4D8O A;  1CB8 A;  1LXK A;  1N7Q A;  4D1J A;  1F1S A;  1EGU A;  1I8Q A;  1HMU A;  1C82 A;  1N7O A;  1X1I A;  2KXS A;  1RWC A;  1OJN A;  2WMI A;  3PQI A;  2E22 A;  4D6D A;  4D6I A;  1W3Y A;  1F9G A;  4D6F A;  4D72 A;  1J0N A;  2X03 A;  1HM2 A;  1RW9 A;  2WMH A;  2BRP A;  1OJM A;  1N7N A;  1OJP A;  1LXM A;  2WMJ A;  3KBT C;  4D1I A;  1J0M A;  3UD2 A; 
#chains in the Genus database with same CATH homology
 3KBU C;  3QR8 A;  4DLO A;  2KXR A;  4DLQ A;  4D8O A;  3F59 A;  3KBT C;  2KXS A;  3UD2 A;  3UD1 A;  3PQI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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