2KXRA

Zo1 zu5 domain mc/aa mutation
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
118
structure length
118
Chain Sequence
TVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPLVAAGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANCVSVLIDHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Tight junction protein ZO-1
total genus 8
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2010-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00791 ZU5 ZU5 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.220.30 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Chondroitinase Ac; Chain A, domain 3 2kxrA01
3KBUC 4D8OA 3UD2A 2KXSA 3F59A 3KBTC 3UD1A 2KXRA
chains in the Genus database with same CATH superfamily
1J0NA 1RWFA 2WCOA 1HM3A 1LXMA 1W3YA 4D6HA 3UD2A 4D6CA 2BRWA 4DLOA 1HN0A 1HM2A 1X1JA 3UD1A 1RW9A 2WMFA 4D1IA 4D6DA 4D6FA 1OJOA 2WMGA 1F9GA 3KBUC 4D8OA 4DLQA 1N7NA 2KXSA 1X1IA 2BRVX 2E22A 2Q1FA 2WDAA 1J0MA 2KXRA 2WMIB 1C82A 1I8QA 1N7RA 4D6IA 1LOHA 1X1HA 1LXKA 1OJPA 1N7QA 3QR8A 1N7PA 4D6EA 1RWAA 4D6GA 2WMHA 1N7OA 1OJNA 1F1SA 2BRPA 2WMJA 2X03A 1EGUA 1RWCA 3U7VA 4D6JA 1OJMA 4D72A 1RWGA 2WMIA 2WMKA 1HMWA 1RWHA 3F59A 4D1JA 4D71A 1CB8A 3KBTC 1HMUA 3PQIA 2E24A
chains in the Genus database with same CATH topology
4DLQA 3KBUC 4D8OA 3UD2A 2KXSA 4DLOA 3F59A 3QR8A 3KBTC 3UD1A 3PQIA 2KXRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KBU C;  4D8O A;  3UD2 A;  2KXS A;  3F59 A;  3KBT C;  3UD1 A;  2KXR A; 
#chains in the Genus database with same CATH topology
 1J0N A;  1RWF A;  2WCO A;  1HM3 A;  1LXM A;  1W3Y A;  4D6H A;  3UD2 A;  4D6C A;  2BRW A;  4DLO A;  1HN0 A;  1HM2 A;  1X1J A;  3UD1 A;  1RW9 A;  2WMF A;  4D1I A;  4D6D A;  4D6F A;  1OJO A;  2WMG A;  1F9G A;  3KBU C;  4D8O A;  4DLQ A;  1N7N A;  2KXS A;  1X1I A;  2BRV X;  2E22 A;  2Q1F A;  2WDA A;  1J0M A;  2KXR A;  2WMI B;  1C82 A;  1I8Q A;  1N7R A;  4D6I A;  1LOH A;  1X1H A;  1LXK A;  1OJP A;  1N7Q A;  3QR8 A;  1N7P A;  4D6E A;  1RWA A;  4D6G A;  2WMH A;  1N7O A;  1OJN A;  1F1S A;  2BRP A;  2WMJ A;  2X03 A;  1EGU A;  1RWC A;  3U7V A;  4D6J A;  1OJM A;  4D72 A;  1RWG A;  2WMI A;  2WMK A;  1HMW A;  1RWH A;  3F59 A;  4D1J A;  4D71 A;  1CB8 A;  3KBT C;  1HMU A;  3PQI A;  2E24 A; 
#chains in the Genus database with same CATH homology
 4DLQ A;  3KBU C;  4D8O A;  3UD2 A;  2KXS A;  4DLO A;  3F59 A;  3QR8 A;  3KBT C;  3UD1 A;  3PQI A;  2KXR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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