1N7RA

Streptococcus pneumoniae hyaluronate lyase w291a/w292a/f343v mutant complex with hexasaccharide hyaluronan
Total Genus 250
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
250
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNAADYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPVKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords HYALURONIDASE
publication title The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
pubmed doi rcsb
source organism Streptococcus pneumoniae
total genus 250
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1n7rA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1n7rA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1n7rA01
4DUVA 1RWGA 2ZXQA 1HM2A 4D6FA 3E7JA 2CIQA 1N7PA 1NS0A 1NSSA 3K25A 4DUXA 1JYWA 1W3YA 1L7JA 1HM3A 1YGAA 2WVXA 1HMWA 2CISA 4OK2A 3I3DA 1HN0A 3VSNA 1LOHA 2E22A 2CIRA 3CZJA 3IAQA 2WMIB 3OS7A 3DCDA 3AFLA 3ECQA 3VDBA 3T2PA 4AQ0A 1C82A 3SEPA 1F4AA 2X03A 1SNZA 3T0DA 3MWXA 3VD7A 1ULVA 4FNVA 4D71A 4DUWA 2WMIA 3Q1NA 2FUTA 2WW2A 3A24A 1L7KA 1J0MA 1EGUA 2BRWA 3MV01 4D6EA 1MMUA 1Z45A 3MUY1 1N7NA 1SO0A 1JZ3A 3VD3A 1NS7A 4TTGA 4F10A 5JMFA 1J0NA 3NJXA 3NJVA 1NSRA 3NFVA 1MMZA 3DECA 1PX3A 2D73A 2WW3A 3MUZ1 2JKEA 1HN1A 2WMGA 3T09A 1JZ4A 1RWFA 1DP0A 2WDAA 1UG9A 2E24A 1NSUA 2WMKA 1OJPA 4D6CA 1OJOA 5JMDA 2ZQ0A 3VD4A 1X1JA 2WMJA 3T0AA 3T2OA 1NSZA 2HTBA 2FUQA 3BGAA 3I3EA 1LF6A 4OK4A 2JKAA 1NS4A 4D6JA 1LF9A 3NREA 4NEIA 1NSXA 1N7QA 1JZ5A 1OJMA 3DYMA 4D6IA 1RWAA 1MMXA 3T08A 3OB8A 5A1AA 1JOVA 3OBAA 1X1IA 1MN0A 1CB8A 1JZ2A 4BZFA 4MMHA 2WCOA 2BRPA 3T0BA 1OJNA 1RW9A 1MMYA 2WW0A 2BRVX 1LXKA 1NS2A 2XSGA 3NNBA 1TXKA 2HTAA 1RWCA 1JYNA 2WMHA 4D72A 1JYVA 3VD9A 3IAPA 2WZSA 1YQ2A 1JZ6A 1K1YA 2Q1FA 1LXMA 2WVZA 3A0OA 4OZWA 4MMIA 1F9GA 2WVYA 3VD5A 1JZ8A 4D6DA 4D6GA 4F13A 4BZEA 1LURA 1N7RA 3T2QA 3I3BA 1N7OA 1PX4A 1I8QA 2JKPA 1NKGA 4BZHA 3WFAA 1HMUA 3MV11 1K1WA 1JZ7A 2XHNA 1JYXA 2WMFA 3VSMA 3IMHA 4D6HA 3DYPA 1X1HA 2WW1A 1K1XA 3E1F1 1QAZA 1F4HA 4OZVA 4RNLA 3E80A 4OJZA 3DYOA 5E1QA 3VDCA 3J7HA 4E1YA 1HV6A 1NSMA 1F1SA 1NS8A 4BZGA 2WVXB 3VDAA 1RWHA 1NSVA
chains in the Genus database with same CATH superfamily
4EHMB 2XQWA 4D1JA 1IA7A 1KFGA 1UT9A 3Q78B 3VXDA 1N95B 1SA4B 2EADA 4DUXA 4M76A 3QXFA 1TN6B 2CISA 1MZCB 3SFXB 2V3NA 3I3DA 3PZ3B 5IL8A 1AVLA 4ZRPA 1IVVA 2OW6A 3EJPA 1TU5A 1FO2A 4BTYA 2YFOA 3SEPA 4LNVA 2JF4A 1NL4B 2Z07A 1WMPA 3BVTA 1PU4A 1N94B 4FUSA 3T0DA 3EJTA 3M77A 3VD7A 5FO8B 3DDGA 2G0DA 1KSDA 2WW2A 3AFJA 5EAUA 1XW2A 3ON6A 1LVNA 4GTOB 1MMUA 3X3XA 1N7NA 4ZG8A 4TTGA 4D94A 1PS3A 1J0NA 4D1IA 3NJVA 3M7EA 1N1BA 3OEDA 2D73A 3DECA 2GH4A 2JKEA 1HN1A 1H14A 1JZ4A 1RWFA 2DRQA 3HXBB 2CG1A 5M7IA 3K5TA 4GTSB 1HXCA 1OJPA 2WYIA 5JMDA 3BUDA 1LTXB 2KXRA 1X1JA 1W5ZA 3EJSA 3SX1A 2BEDB 3E32B 3BGAA 3I3EA 3D4ZA 1N4SB 3M02A 5GZKA 1H35A 2A8ZA 3QT9A 2DRSA 2FV0A 1JZ5A 1L1YA 3BUPA 3DSUB 4BTXA 4YCRA 4BOKA 3DPYB 5ILIA 3BLBA 3S4DA 2XN2A 2FUZA 4EV2A 1H3CA 1WZZA 4BZFA 1WMNA 1CLCA 1FBWA 2BRPA 5IKAA 3T0BA 1D8EB 4D4BA 3DSXB 3PZ1B 1MMYA 2OKXA 4KTRA 1NS2A 3E73A 3BVUA 2WOHA 3EU8A 3NNBA 4FNRA 3HI7A 1RWCA 2CFDA 1W6JA 2WMHA 5ILJA 4WU0A 1FP3A 3P2CA 1YQ2A 1XWTA 1QSJA 5CD2A 4GL3A 1AGMA 2WVZA 1F9GA 2WVYA 4YDOB 5ILKA 1JZ8A 1O6HA 4D6GA 3I3BA 1I8QA 3X3ZA 3ANIA 1NC5A 3WA3A 3S4CA 1HXAA 2CFGA 3CZSA 3OXUA 3MV11 3VSMA 3D4YA 3IMHA 3DYPA 2JG0A 3PYAA 2WW1A 1TN8B 4OZVA 4RNLA 2G02A 5IK0A 1JCQB 3HXDB 4DODA 3DYOA 3NBJA 2DRRA 3NBBA 1HWWA 1GA2A 2ALWA 3GT5A 3QPFA 1N1ZA 3H3KA 4BZGA 2WINB 2WVXB 3VDAA 1RWHA 2FYVA 4Q88A 1RWGA 2ONHA 3PGBA 2GOXA 1TQWA 3P5PA 2CIQA 2F0YB 2I07B 3KBTC 1W6KA 2VN4A 1NSSA 2OQEA 3K25A 3WKFA 1JYWA 4C1SA 1W3YA 3X17A 3M7CA 2CG0A 2WVXA 3Q7FB 1HMWA 3E34B 3D52A 4L6XA 3K11A 2CIRA 3IAQA 2QNOA 3D5SA 1SQCA 2CQTA 2IEJB 5EASA 3UD1A 1IA6A 4ZRQA 3VDBA 2CFKA 3T2PA 1VD5A 4D4DA 1KS8A 1HXGA 3DSTB 4FXGB 4QT9A 1F4AA 4AQ0A 1G9GA 4YDEB 5MEHA 4CJ1A 5IK9A 3H7LA 1W6GA 1ULVA 4FNVA 5C05A 1FT1B 5FO7B 1O1SB 5JPNB 3K7XA 2FUTA 4CE7A 3W5NA 2V3PA 2RGKA 3HIIA 4AYQA 1A2VA 1IVXA 1UI7A 1SO0A 1Z45A 3MI6A 2SQCA 1O79A 3F59A 4LNGB 2NVPA 4F10A 5JMFA 2WYHA 3KIIA 1NSRA 2YIKA 4V1SA 3LZ9A 3M00A 1MMZA 3BVVA 3T09A 2WMGA 1IQYA 2V8IA 3M71A 2RI8A 2WDAA 3BUBA 1NSUA 1HX9A 1H3BA 3VD4A 3ALAA 4FNSA 4DLOA 2H6IB 2EABA 2BBCA 2ZZRA 2FUQA 1GXOA 2WYNA 4V1RA 2F7RA 3EJRA 3PZ4B 4TF4A 1F9DA 4EL8A 5FO9B 1LF9A 1KZOB 5DGRA 1N7QA 4Z4LA 5KKBA 3DYMA 2XFGA 1RWAA 3CU7A 3HXEB 2PMVA 1MN0A 1TN7B 1JZ2A 1O1TB 3WIQA 2Y74A 1DOGA 1S64B 1W2ZA 3Q79B 3DDFA 3M75A 1QBQB 3E6UA 1LD8B 2BRVX 4FXKB 3S4BA 1N9AB 1AV4A 3VW5A 5IL3A 4ONTA 1FMIA 1HXKA 3PQIA 3ACSA 4D72A 5IM1A 2CWUA 1FAEA 3H2WA 2OOVC 3BUQA 3IAPA 1JYVA 1RKYA 5ILDA 1IQXA 1JZ6A 1KSCA 1KSIA 3A0OA 3VD5A 3QDEA 2W0QA 4BZEA 1UMPA 3M7BA 3BUIA 3T2QA 1R34A 1PX4A 2F6DA 1FT2B 4FNPA 2H6HB 1HMUA 3SDRA 2R2LB 1XWQA 2FBAA 1V5DA 1X1HA 3X41A 1K1XA 3G4DA 3E80A 4OJZA 4GTVB 5E1QA 4WVAA 3QR8A 1WU5A 1W6CA 3P5RA 2Y73A 3LVTA 3J7HA 1HV6A 1EKMA 1R33A 1F1SA 5E2JA 3DX1A 2YFNA 2E2TA 1NSVA 3AMOB 3CZNA 2ZXQA 1HM2A 1FO3A 3N0FA 4WVBA 5DGQA 4D6FA 1RQ5A 3E7JA 1N7PA 1NS0A 3SFYB 1TF4A 4XUVA 2XWBB 3EQAA 2YX9A 2F1BA 1DCEB 3AMOA 3SDTA 4K3AA 2PNCA 1N23A 4AYPA 1QAFA 1FPPB 2E22A 2XN0A 3OS7A 3D3IA 3CV5A 3ECQA 4EV5A 2OW7A 1F9OA 1C82A 3WC3A 1W4NA 1TNUB 4L9PB 2X03A 4KKIA 3EJUA 1QQFA 3SQCA 1GLMA 3EUVB 3WVFA 3QSPA 5GY3A 3M74A 3M72A 3A24A 1L7KA 1J0MA 1EGUA 2BRWA 3RJ3A 4D6EA 3KSQB 3MUY1 3DSVB 3PYBA 3DX2A 2WOFA 3T0UA 2EAEA 1KZPB 2F7OA 3BVWA 1IS9A 2WY8A 2NOJA 1PX3A 2WW3A 3MUZ1 1DP0A 3T33A 2E24A 2XWJB 4KKJA 2H6FB 2EACA 4ZH1A 4D6CA 2ZQ0A 2WMJA 1WU6A 1NI1B 1N21A 4KFFA 3C72B 2A73B 1JCSB 3RX7A 3W7UA 3U7VA 2HTBA 5M7YA 1LF6A 1H36A 1N20A 4OK4A 3X42A 4L0GA 5ILZA 2C11A 1WMOA 4D6JA 3W5MA 4AYRA 3TY1A 1O5MB 3NREA 1NSXA 3ANJA 3BVXA 4GTPB 2D8LA 1KRFA 5KBPA 1OJMA 4D4CA 3KBUC 3X3YA 3E33B 4D6IA 1O6RA 1UI8A 1H13A 2D5JA 1MMXA 1D6UA 4GTMB 4FNUA 3RX8A 3T08A 1JOVA 5A1AA 4D4AA 2XN1A 3OBAA 1G6IA 2E2UA 3HXFB 1CB8A 1QWUA 1JCRB 3RX5A 3BS6A 3DX0A 3WKIA 2ONGA 2WCOA 2F7QA 1OJNA 1KWFA 2F7PA 5CA3A 1OACA 2ZIRB 2WGQA 3X40A 1LXKA 3WA2X 2XSGA 1TXKA 1SA5B 1FCEA 1GSZA 1N24A 4Q2BA 2RDYA 1IU7A 2WZSA 2ZL8A 2CQSA 3WKGA 2DROA 3Q75B 5DHIA 3RENA 4MMIA 3S9VA 1QAKA 1IVWA 4D6DA 4FNTA 1LD7B 1LURA 2E2VA 2OOVA 2GZ6A 4WVCA 3Q7AB 1O1RB 3DX3A 2B39A 2PN5A 2F18A 2JKPA 1N4RB 3RRSA 3WFAA 1X81B 1K1WA 1JZ7A 1JYXA 2ZBLA 1NXCA 1V7VA 1H3AA 4D6HA 2D1WA 3A3VA 3E1F1 1QAZA 1F4HA 1GXMA 5ILYA 5EATA 1HTYA 1X9DA 1H39A 1GXNA 3HXCB 3UD2A 1GAHA 3MPHA 1SIHA 3QFZA 4E1YA 1NSMA 3KQ4A 3SXXA 1NS8A 4DUVA 1KREA 1HZFA 3SDUA 4LIXA 2BB6A 1GHQA 5ILHA 1V5CA 1TNOB 3PMMA 1L7JA 5IKHA 1RJOA 1HM3A 1YGAA 1N22A 3HIGA 4OK2A 1TNZB 3M73A 4CJ0A 3GLYA 1HN0A 3VSNA 1O6QA 1LOHA 1QALA 3QFYA 3CZJA 3GZKA 3W7WA 2WMIB 1SPUA 4AYOA 3DCDA 3AFLA 3M76A 4GTTB 1GAIA 1N4PB 2H6GB 1G9JA 5CZLA 2KXSA 1S63B 1O7DD 3G4FA 1SNZA 3MWXA 2CWTA 4D71A 4DUWA 2WMIA 4GAXA 1D6YA 3Q1NA 3S4AA 2P0VA 4MBGB 4FNQA 1FBOA 1WU4A 3RSYA 1JRQA 3KN4A 3EZ8A 1N9EA 3MV01 1JZ3A 3M01A 2B4FA 1NS7A 3VD3A 3KLSA 1TQUA 3NJXA 3SDQA 3WKHA 2BB5A 3NFVA 1KKTA 3SDVA 4DI5A 4BOJA 4TXTA 1G87A 1UG9A 4BTWA 3DSWB 1US1A 1TQVA 1C3DA 1D6ZA 3QRYA 2WMKA 2CWVA 1DL2A 1H12A 1OJOA 2WO0A 4UFCA 3T0AA 2J5CA 4KFDA 3T2OA 1NSZA 1AVKA 1TQTA 1DYUA 2V8JA 3TF4A 3DSSB 2JKAA 4GTQB 1NS4A 1N4QB 1L2AA 1SIIA 2BT3A 5DHKA 3WIWA 3ACTA 4NEIA 1CEMA 2WY7A 4DLQA 3G6JB 3D50A 4K35A 1H54A 1QWNA 3DRAB 2CFWA 3OB8A 4Z4JA 4GTRB 3W7SA 3M78A 1X1IA 2RI9A 3D5RA 4MMHA 4DOEA 2FV1A 3PZ2B 5GW7A 3EU5B 3QXQA 2WIIB 5JPMB 3W7XA 3W7TA 1TQSA 2C10A 1RW9A 2WW0A 1TNYB 2HTAA 1JYNA 1K72A 1V7WA 3M7LA 3VD9A 3Q73B 3EJQA 1W7CA 1HCUA 3WUXA 3E37B 4JJJA 4MU9A 1K1YA 2Q1FA 2CFLA 1LXMA 3QT3A 4OZWA 1AYXA 2ZISB 4J5TA 4RNQA 3QWTA 4F13A 1N7RA 2AFAA 1D8DB 2VN7A 1N7OA 1H37A 2V8KA 1NKGA 1QX1A 4BZHA 3KSLB 2AHFA 2JJBA 4FJQA 5IK6A 1V7XA 2WMFA 3QG0A 1IVUA 2XHNA 3DX4A 4KFEA 4KTPA 3E30B 4ZH5A 3N9HA 2AHGA 1JS4A 3BLCA 4LNBB 1R76A 5FOBB 4D8OA 5AGDA 3VDCA 1TNBB 2OQEC 3D51A 3LOYA 2F1AA 3CIHA 3ANKA 3WIRA 3N0GA 3SAEA
chains in the Genus database with same CATH topology
4DUVA 1RWGA 2ZXQA 1HM2A 4D6FA 3E7JA 2CIQA 1N7PA 1NS0A 1NSSA 3K25A 4DUXA 1JYWA 1W3YA 1L7JA 1HM3A 1YGAA 2WVXA 1HMWA 2CISA 4OK2A 3I3DA 1HN0A 3VSNA 1LOHA 2E22A 2CIRA 3CZJA 3IAQA 2WMIB 3OS7A 3DCDA 3AFLA 3ECQA 3VDBA 3T2PA 4AQ0A 1C82A 3SEPA 1F4AA 2X03A 1SNZA 3T0DA 3MWXA 3VD7A 1ULVA 4FNVA 4D71A 3WVFA 4DUWA 2WMIA 3Q1NA 2FUTA 2WW2A 3A24A 1L7KA 1J0MA 1EGUA 2BRWA 3MV01 4D6EA 1MMUA 1Z45A 3MUY1 1N7NA 1SO0A 1JZ3A 3VD3A 1NS7A 4TTGA 4F10A 5JMFA 1J0NA 3NJXA 3NJVA 1NSRA 3NFVA 1MMZA 3DECA 1PX3A 2D73A 2WW3A 3MUZ1 2JKEA 1HN1A 2WMGA 3T09A 1JZ4A 1RWFA 1DP0A 2WDAA 1UG9A 2E24A 1NSUA 2WMKA 1OJPA 4D6CA 1OJOA 5JMDA 2ZQ0A 3VD4A 1X1JA 2WMJA 3T0AA 3T2OA 1NSZA 2HTBA 2FUQA 3BGAA 3I3EA 1LF6A 4OK4A 2JKAA 1NS4A 4D6JA 3TY1A 1LF9A 3NREA 4NEIA 1NSXA 1N7QA 1JZ5A 1OJMA 3DYMA 4D6IA 1RWAA 1MMXA 3T08A 3OB8A 5A1AA 1JOVA 3OBAA 1X1IA 1MN0A 1CB8A 1JZ2A 3BS6A 4BZFA 4MMHA 2WCOA 2BRPA 3T0BA 1OJNA 1RW9A 1MMYA 2WW0A 2BRVX 1LXKA 1NS2A 2XSGA 3NNBA 1TXKA 2HTAA 1RWCA 1JYNA 2WMHA 4D72A 1JYVA 3VD9A 3IAPA 2WZSA 1YQ2A 1JZ6A 1K1YA 2Q1FA 1LXMA 2WVZA 3A0OA 4OZWA 4MMIA 1F9GA 2WVYA 3VD5A 4J5TA 4D6DA 4D6GA 4F13A 4BZEA 1LURA 1JZ8A 1N7RA 3T2QA 3I3BA 1N7OA 1PX4A 1I8QA 2JKPA 1NKGA 4BZHA 3WFAA 1HMUA 3MV11 1K1WA 1JZ7A 2XHNA 1JYXA 2WMFA 3VSMA 3IMHA 4D6HA 3DYPA 1X1HA 2WW1A 3BLCA 1K1XA 3E1F1 1QAZA 1F4HA 4OZVA 4RNLA 3E80A 4OJZA 3DYOA 5E1QA 3VDCA 3J7HA 4E1YA 1HV6A 1NSMA 1F1SA 1NS8A 4BZGA 2WVXB 3VDAA 1RWHA 1NSVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DUV A;  1RWG A;  2ZXQ A;  1HM2 A;  4D6F A;  3E7J A;  2CIQ A;  1N7P A;  1NS0 A;  1NSS A;  3K25 A;  4DUX A;  1JYW A;  1W3Y A;  1L7J A;  1HM3 A;  1YGA A;  2WVX A;  1HMW A;  2CIS A;  4OK2 A;  3I3D A;  1HN0 A;  3VSN A;  1LOH A;  2E22 A;  2CIR A;  3CZJ A;  3IAQ A;  2WMI B;  3OS7 A;  3DCD A;  3AFL A;  3ECQ A;  3VDB A;  3T2P A;  4AQ0 A;  1C82 A;  3SEP A;  1F4A A;  2X03 A;  1SNZ A;  3T0D A;  3MWX A;  3VD7 A;  1ULV A;  4FNV A;  4D71 A;  4DUW A;  2WMI A;  3Q1N A;  2FUT A;  2WW2 A;  3A24 A;  1L7K A;  1J0M A;  1EGU A;  2BRW A;  3MV0 1;  4D6E A;  1MMU A;  1Z45 A;  3MUY 1;  1N7N A;  1SO0 A;  1JZ3 A;  3VD3 A;  1NS7 A;  4TTG A;  4F10 A;  5JMF A;  1J0N A;  3NJX A;  3NJV A;  1NSR A;  3NFV A;  1MMZ A;  3DEC A;  1PX3 A;  2D73 A;  2WW3 A;  3MUZ 1;  2JKE A;  1HN1 A;  2WMG A;  3T09 A;  1JZ4 A;  1RWF A;  1DP0 A;  2WDA A;  1UG9 A;  2E24 A;  1NSU A;  2WMK A;  1OJP A;  4D6C A;  1OJO A;  5JMD A;  2ZQ0 A;  3VD4 A;  1X1J A;  2WMJ A;  3T0A A;  3T2O A;  1NSZ A;  2HTB A;  2FUQ A;  3BGA A;  3I3E A;  1LF6 A;  4OK4 A;  2JKA A;  1NS4 A;  4D6J A;  1LF9 A;  3NRE A;  4NEI A;  1NSX A;  1N7Q A;  1JZ5 A;  1OJM A;  3DYM A;  4D6I A;  1RWA A;  1MMX A;  3T08 A;  3OB8 A;  5A1A A;  1JOV A;  3OBA A;  1X1I A;  1MN0 A;  1CB8 A;  1JZ2 A;  4BZF A;  4MMH A;  2WCO A;  2BRP A;  3T0B A;  1OJN A;  1RW9 A;  1MMY A;  2WW0 A;  2BRV X;  1LXK A;  1NS2 A;  2XSG A;  3NNB A;  1TXK A;  2HTA A;  1RWC A;  1JYN A;  2WMH A;  4D72 A;  1JYV A;  3VD9 A;  3IAP A;  2WZS A;  1YQ2 A;  1JZ6 A;  1K1Y A;  2Q1F A;  1LXM A;  2WVZ A;  3A0O A;  4OZW A;  4MMI A;  1F9G A;  2WVY A;  3VD5 A;  1JZ8 A;  4D6D A;  4D6G A;  4F13 A;  4BZE A;  1LUR A;  1N7R A;  3T2Q A;  3I3B A;  1N7O A;  1PX4 A;  1I8Q A;  2JKP A;  1NKG A;  4BZH A;  3WFA A;  1HMU A;  3MV1 1;  1K1W A;  1JZ7 A;  2XHN A;  1JYX A;  2WMF A;  3VSM A;  3IMH A;  4D6H A;  3DYP A;  1X1H A;  2WW1 A;  1K1X A;  3E1F 1;  1QAZ A;  1F4H A;  4OZV A;  4RNL A;  3E80 A;  4OJZ A;  3DYO A;  5E1Q A;  3VDC A;  3J7H A;  4E1Y A;  1HV6 A;  1NSM A;  1F1S A;  1NS8 A;  4BZG A;  2WVX B;  3VDA A;  1RWH A;  1NSV A; 
#chains in the Genus database with same CATH topology
 4EHM B;  2XQW A;  4D1J A;  1IA7 A;  1KFG A;  1UT9 A;  3Q78 B;  3VXD A;  1N95 B;  1SA4 B;  2EAD A;  4DUX A;  4M76 A;  3QXF A;  1TN6 B;  2CIS A;  1MZC B;  3SFX B;  2V3N A;  3I3D A;  3PZ3 B;  5IL8 A;  1AVL A;  4ZRP A;  1IVV A;  2OW6 A;  3EJP A;  1TU5 A;  1FO2 A;  4BTY A;  2YFO A;  3SEP A;  4LNV A;  2JF4 A;  1NL4 B;  2Z07 A;  1WMP A;  3BVT A;  1PU4 A;  1N94 B;  4FUS A;  3T0D A;  3EJT A;  3M77 A;  3VD7 A;  5FO8 B;  3DDG A;  2G0D A;  1KSD A;  2WW2 A;  3AFJ A;  5EAU A;  1XW2 A;  3ON6 A;  1LVN A;  4GTO B;  1MMU A;  3X3X A;  1N7N A;  4ZG8 A;  4TTG A;  4D94 A;  1PS3 A;  1J0N A;  4D1I A;  3NJV A;  3M7E A;  1N1B A;  3OED A;  2D73 A;  3DEC A;  2GH4 A;  2JKE A;  1HN1 A;  1H14 A;  1JZ4 A;  1RWF A;  2DRQ A;  3HXB B;  2CG1 A;  5M7I A;  3K5T A;  4GTS B;  1HXC A;  1OJP A;  2WYI A;  5JMD A;  3BUD A;  1LTX B;  2KXR A;  1X1J A;  1W5Z A;  3EJS A;  3SX1 A;  2BED B;  3E32 B;  3BGA A;  3I3E A;  3D4Z A;  1N4S B;  3M02 A;  5GZK A;  1H35 A;  2A8Z A;  3QT9 A;  2DRS A;  2FV0 A;  1JZ5 A;  1L1Y A;  3BUP A;  3DSU B;  4BTX A;  4YCR A;  4BOK A;  3DPY B;  5ILI A;  3BLB A;  3S4D A;  2XN2 A;  2FUZ A;  4EV2 A;  1H3C A;  1WZZ A;  4BZF A;  1WMN A;  1CLC A;  1FBW A;  2BRP A;  5IKA A;  3T0B A;  1D8E B;  4D4B A;  3DSX B;  3PZ1 B;  1MMY A;  2OKX A;  4KTR A;  1NS2 A;  3E73 A;  3BVU A;  2WOH A;  3EU8 A;  3NNB A;  4FNR A;  3HI7 A;  1RWC A;  2CFD A;  1W6J A;  2WMH A;  5ILJ A;  4WU0 A;  1FP3 A;  3P2C A;  1YQ2 A;  1XWT A;  1QSJ A;  5CD2 A;  4GL3 A;  1AGM A;  2WVZ A;  1F9G A;  2WVY A;  4YDO B;  5ILK A;  1JZ8 A;  1O6H A;  4D6G A;  3I3B A;  1I8Q A;  3X3Z A;  3ANI A;  1NC5 A;  3WA3 A;  3S4C A;  1HXA A;  2CFG A;  3CZS A;  3OXU A;  3MV1 1;  3VSM A;  3D4Y A;  3IMH A;  3DYP A;  2JG0 A;  3PYA A;  2WW1 A;  1TN8 B;  4OZV A;  4RNL A;  2G02 A;  5IK0 A;  1JCQ B;  3HXD B;  4DOD A;  3DYO A;  3NBJ A;  2DRR A;  3NBB A;  1HWW A;  1GA2 A;  2ALW A;  3GT5 A;  3QPF A;  1N1Z A;  3H3K A;  4BZG A;  2WIN B;  2WVX B;  3VDA A;  1RWH A;  2FYV A;  4Q88 A;  1RWG A;  2ONH A;  3PGB A;  2GOX A;  1TQW A;  3P5P A;  2CIQ A;  2F0Y B;  2I07 B;  3KBT C;  1W6K A;  2VN4 A;  1NSS A;  2OQE A;  3K25 A;  3WKF A;  1JYW A;  4C1S A;  1W3Y A;  3X17 A;  3M7C A;  2CG0 A;  2WVX A;  3Q7F B;  1HMW A;  3E34 B;  3D52 A;  4L6X A;  3K11 A;  2CIR A;  3IAQ A;  2QNO A;  3D5S A;  1SQC A;  2CQT A;  2IEJ B;  5EAS A;  3UD1 A;  1IA6 A;  4ZRQ A;  3VDB A;  2CFK A;  3T2P A;  1VD5 A;  4D4D A;  1KS8 A;  1HXG A;  3DST B;  4FXG B;  4QT9 A;  1F4A A;  4AQ0 A;  1G9G A;  4YDE B;  5MEH A;  4CJ1 A;  5IK9 A;  3H7L A;  1W6G A;  1ULV A;  4FNV A;  5C05 A;  1FT1 B;  5FO7 B;  1O1S B;  5JPN B;  3K7X A;  2FUT A;  4CE7 A;  3W5N A;  2V3P A;  2RGK A;  3HII A;  4AYQ A;  1A2V A;  1IVX A;  1UI7 A;  1SO0 A;  1Z45 A;  3MI6 A;  2SQC A;  1O79 A;  3F59 A;  4LNG B;  2NVP A;  4F10 A;  5JMF A;  2WYH A;  3KII A;  1NSR A;  2YIK A;  4V1S A;  3LZ9 A;  3M00 A;  1MMZ A;  3BVV A;  3T09 A;  2WMG A;  1IQY A;  2V8I A;  3M71 A;  2RI8 A;  2WDA A;  3BUB A;  1NSU A;  1HX9 A;  1H3B A;  3VD4 A;  3ALA A;  4FNS A;  4DLO A;  2H6I B;  2EAB A;  2BBC A;  2ZZR A;  2FUQ A;  1GXO A;  2WYN A;  4V1R A;  2F7R A;  3EJR A;  3PZ4 B;  4TF4 A;  1F9D A;  4EL8 A;  5FO9 B;  1LF9 A;  1KZO B;  5DGR A;  1N7Q A;  4Z4L A;  5KKB A;  3DYM A;  2XFG A;  1RWA A;  3CU7 A;  3HXE B;  2PMV A;  1MN0 A;  1TN7 B;  1JZ2 A;  1O1T B;  3WIQ A;  2Y74 A;  1DOG A;  1S64 B;  1W2Z A;  3Q79 B;  3DDF A;  3M75 A;  1QBQ B;  3E6U A;  1LD8 B;  2BRV X;  4FXK B;  3S4B A;  1N9A B;  1AV4 A;  3VW5 A;  5IL3 A;  4ONT A;  1FMI A;  1HXK A;  3PQI A;  3ACS A;  4D72 A;  5IM1 A;  2CWU A;  1FAE A;  3H2W A;  2OOV C;  3BUQ A;  3IAP A;  1JYV A;  1RKY A;  5ILD A;  1IQX A;  1JZ6 A;  1KSC A;  1KSI A;  3A0O A;  3VD5 A;  3QDE A;  2W0Q A;  4BZE A;  1UMP A;  3M7B A;  3BUI A;  3T2Q A;  1R34 A;  1PX4 A;  2F6D A;  1FT2 B;  4FNP A;  2H6H B;  1HMU A;  3SDR A;  2R2L B;  1XWQ A;  2FBA A;  1V5D A;  1X1H A;  3X41 A;  1K1X A;  3G4D A;  3E80 A;  4OJZ A;  4GTV B;  5E1Q A;  4WVA A;  3QR8 A;  1WU5 A;  1W6C A;  3P5R A;  2Y73 A;  3LVT A;  3J7H A;  1HV6 A;  1EKM A;  1R33 A;  1F1S A;  5E2J A;  3DX1 A;  2YFN A;  2E2T A;  1NSV A;  3AMO B;  3CZN A;  2ZXQ A;  1HM2 A;  1FO3 A;  3N0F A;  4WVB A;  5DGQ A;  4D6F A;  1RQ5 A;  3E7J A;  1N7P A;  1NS0 A;  3SFY B;  1TF4 A;  4XUV A;  2XWB B;  3EQA A;  2YX9 A;  2F1B A;  1DCE B;  3AMO A;  3SDT A;  4K3A A;  2PNC A;  1N23 A;  4AYP A;  1QAF A;  1FPP B;  2E22 A;  2XN0 A;  3OS7 A;  3D3I A;  3CV5 A;  3ECQ A;  4EV5 A;  2OW7 A;  1F9O A;  1C82 A;  3WC3 A;  1W4N A;  1TNU B;  4L9P B;  2X03 A;  4KKI A;  3EJU A;  1QQF A;  3SQC A;  1GLM A;  3EUV B;  3WVF A;  3QSP A;  5GY3 A;  3M74 A;  3M72 A;  3A24 A;  1L7K A;  1J0M A;  1EGU A;  2BRW A;  3RJ3 A;  4D6E A;  3KSQ B;  3MUY 1;  3DSV B;  3PYB A;  3DX2 A;  2WOF A;  3T0U A;  2EAE A;  1KZP B;  2F7O A;  3BVW A;  1IS9 A;  2WY8 A;  2NOJ A;  1PX3 A;  2WW3 A;  3MUZ 1;  1DP0 A;  3T33 A;  2E24 A;  2XWJ B;  4KKJ A;  2H6F B;  2EAC A;  4ZH1 A;  4D6C A;  2ZQ0 A;  2WMJ A;  1WU6 A;  1NI1 B;  1N21 A;  4KFF A;  3C72 B;  2A73 B;  1JCS B;  3RX7 A;  3W7U A;  3U7V A;  2HTB A;  5M7Y A;  1LF6 A;  1H36 A;  1N20 A;  4OK4 A;  3X42 A;  4L0G A;  5ILZ A;  2C11 A;  1WMO A;  4D6J A;  3W5M A;  4AYR A;  3TY1 A;  1O5M B;  3NRE A;  1NSX A;  3ANJ A;  3BVX A;  4GTP B;  2D8L A;  1KRF A;  5KBP A;  1OJM A;  4D4C A;  3KBU C;  3X3Y A;  3E33 B;  4D6I A;  1O6R A;  1UI8 A;  1H13 A;  2D5J A;  1MMX A;  1D6U A;  4GTM B;  4FNU A;  3RX8 A;  3T08 A;  1JOV A;  5A1A A;  4D4A A;  2XN1 A;  3OBA A;  1G6I A;  2E2U A;  3HXF B;  1CB8 A;  1QWU A;  1JCR B;  3RX5 A;  3BS6 A;  3DX0 A;  3WKI A;  2ONG A;  2WCO A;  2F7Q A;  1OJN A;  1KWF A;  2F7P A;  5CA3 A;  1OAC A;  2ZIR B;  2WGQ A;  3X40 A;  1LXK A;  3WA2 X;  2XSG A;  1TXK A;  1SA5 B;  1FCE A;  1GSZ A;  1N24 A;  4Q2B A;  2RDY A;  1IU7 A;  2WZS A;  2ZL8 A;  2CQS A;  3WKG A;  2DRO A;  3Q75 B;  5DHI A;  3REN A;  4MMI A;  3S9V A;  1QAK A;  1IVW A;  4D6D A;  4FNT A;  1LD7 B;  1LUR A;  2E2V A;  2OOV A;  2GZ6 A;  4WVC A;  3Q7A B;  1O1R B;  3DX3 A;  2B39 A;  2PN5 A;  2F18 A;  2JKP A;  1N4R B;  3RRS A;  3WFA A;  1X81 B;  1K1W A;  1JZ7 A;  1JYX A;  2ZBL A;  1NXC A;  1V7V A;  1H3A A;  4D6H A;  2D1W A;  3A3V A;  3E1F 1;  1QAZ A;  1F4H A;  1GXM A;  5ILY A;  5EAT A;  1HTY A;  1X9D A;  1H39 A;  1GXN A;  3HXC B;  3UD2 A;  1GAH A;  3MPH A;  1SIH A;  3QFZ A;  4E1Y A;  1NSM A;  3KQ4 A;  3SXX A;  1NS8 A;  4DUV A;  1KRE A;  1HZF A;  3SDU A;  4LIX A;  2BB6 A;  1GHQ A;  5ILH A;  1V5C A;  1TNO B;  3PMM A;  1L7J A;  5IKH A;  1RJO A;  1HM3 A;  1YGA A;  1N22 A;  3HIG A;  4OK2 A;  1TNZ B;  3M73 A;  4CJ0 A;  3GLY A;  1HN0 A;  3VSN A;  1O6Q A;  1LOH A;  1QAL A;  3QFY A;  3CZJ A;  3GZK A;  3W7W A;  2WMI B;  1SPU A;  4AYO A;  3DCD A;  3AFL A;  3M76 A;  4GTT B;  1GAI A;  1N4P B;  2H6G B;  1G9J A;  5CZL A;  2KXS A;  1S63 B;  1O7D D;  3G4F A;  1SNZ A;  3MWX A;  2CWT A;  4D71 A;  4DUW A;  2WMI A;  4GAX A;  1D6Y A;  3Q1N A;  3S4A A;  2P0V A;  4MBG B;  4FNQ A;  1FBO A;  1WU4 A;  3RSY A;  1JRQ A;  3KN4 A;  3EZ8 A;  1N9E A;  3MV0 1;  1JZ3 A;  3M01 A;  2B4F A;  1NS7 A;  3VD3 A;  3KLS A;  1TQU A;  3NJX A;  3SDQ A;  3WKH A;  2BB5 A;  3NFV A;  1KKT A;  3SDV A;  4DI5 A;  4BOJ A;  4TXT A;  1G87 A;  1UG9 A;  4BTW A;  3DSW B;  1US1 A;  1TQV A;  1C3D A;  1D6Z A;  3QRY A;  2WMK A;  2CWV A;  1DL2 A;  1H12 A;  1OJO A;  2WO0 A;  4UFC A;  3T0A A;  2J5C A;  4KFD A;  3T2O A;  1NSZ A;  1AVK A;  1TQT A;  1DYU A;  2V8J A;  3TF4 A;  3DSS B;  2JKA A;  4GTQ B;  1NS4 A;  1N4Q B;  1L2A A;  1SII A;  2BT3 A;  5DHK A;  3WIW A;  3ACT A;  4NEI A;  1CEM A;  2WY7 A;  4DLQ A;  3G6J B;  3D50 A;  4K35 A;  1H54 A;  1QWN A;  3DRA B;  2CFW A;  3OB8 A;  4Z4J A;  4GTR B;  3W7S A;  3M78 A;  1X1I A;  2RI9 A;  3D5R A;  4MMH A;  4DOE A;  2FV1 A;  3PZ2 B;  5GW7 A;  3EU5 B;  3QXQ A;  2WII B;  5JPM B;  3W7X A;  3W7T A;  1TQS A;  2C10 A;  1RW9 A;  2WW0 A;  1TNY B;  2HTA A;  1JYN A;  1K72 A;  1V7W A;  3M7L A;  3VD9 A;  3Q73 B;  3EJQ A;  1W7C A;  1HCU A;  3WUX A;  3E37 B;  4JJJ A;  4MU9 A;  1K1Y A;  2Q1F A;  2CFL A;  1LXM A;  3QT3 A;  4OZW A;  1AYX A;  2ZIS B;  4J5T A;  4RNQ A;  3QWT A;  4F13 A;  1N7R A;  2AFA A;  1D8D B;  2VN7 A;  1N7O A;  1H37 A;  2V8K A;  1NKG A;  1QX1 A;  4BZH A;  3KSL B;  2AHF A;  2JJB A;  4FJQ A;  5IK6 A;  1V7X A;  2WMF A;  3QG0 A;  1IVU A;  2XHN A;  3DX4 A;  4KFE A;  4KTP A;  3E30 B;  4ZH5 A;  3N9H A;  2AHG A;  1JS4 A;  3BLC A;  4LNB B;  1R76 A;  5FOB B;  4D8O A;  5AGD A;  3VDC A;  1TNB B;  2OQE C;  3D51 A;  3LOY A;  2F1A A;  3CIH A;  3ANK A;  3WIR A;  3N0G A;  3SAE A; 
#chains in the Genus database with same CATH homology
 4DUV A;  1RWG A;  2ZXQ A;  1HM2 A;  4D6F A;  3E7J A;  2CIQ A;  1N7P A;  1NS0 A;  1NSS A;  3K25 A;  4DUX A;  1JYW A;  1W3Y A;  1L7J A;  1HM3 A;  1YGA A;  2WVX A;  1HMW A;  2CIS A;  4OK2 A;  3I3D A;  1HN0 A;  3VSN A;  1LOH A;  2E22 A;  2CIR A;  3CZJ A;  3IAQ A;  2WMI B;  3OS7 A;  3DCD A;  3AFL A;  3ECQ A;  3VDB A;  3T2P A;  4AQ0 A;  1C82 A;  3SEP A;  1F4A A;  2X03 A;  1SNZ A;  3T0D A;  3MWX A;  3VD7 A;  1ULV A;  4FNV A;  4D71 A;  3WVF A;  4DUW A;  2WMI A;  3Q1N A;  2FUT A;  2WW2 A;  3A24 A;  1L7K A;  1J0M A;  1EGU A;  2BRW A;  3MV0 1;  4D6E A;  1MMU A;  1Z45 A;  3MUY 1;  1N7N A;  1SO0 A;  1JZ3 A;  3VD3 A;  1NS7 A;  4TTG A;  4F10 A;  5JMF A;  1J0N A;  3NJX A;  3NJV A;  1NSR A;  3NFV A;  1MMZ A;  3DEC A;  1PX3 A;  2D73 A;  2WW3 A;  3MUZ 1;  2JKE A;  1HN1 A;  2WMG A;  3T09 A;  1JZ4 A;  1RWF A;  1DP0 A;  2WDA A;  1UG9 A;  2E24 A;  1NSU A;  2WMK A;  1OJP A;  4D6C A;  1OJO A;  5JMD A;  2ZQ0 A;  3VD4 A;  1X1J A;  2WMJ A;  3T0A A;  3T2O A;  1NSZ A;  2HTB A;  2FUQ A;  3BGA A;  3I3E A;  1LF6 A;  4OK4 A;  2JKA A;  1NS4 A;  4D6J A;  3TY1 A;  1LF9 A;  3NRE A;  4NEI A;  1NSX A;  1N7Q A;  1JZ5 A;  1OJM A;  3DYM A;  4D6I A;  1RWA A;  1MMX A;  3T08 A;  3OB8 A;  5A1A A;  1JOV A;  3OBA A;  1X1I A;  1MN0 A;  1CB8 A;  1JZ2 A;  3BS6 A;  4BZF A;  4MMH A;  2WCO A;  2BRP A;  3T0B A;  1OJN A;  1RW9 A;  1MMY A;  2WW0 A;  2BRV X;  1LXK A;  1NS2 A;  2XSG A;  3NNB A;  1TXK A;  2HTA A;  1RWC A;  1JYN A;  2WMH A;  4D72 A;  1JYV A;  3VD9 A;  3IAP A;  2WZS A;  1YQ2 A;  1JZ6 A;  1K1Y A;  2Q1F A;  1LXM A;  2WVZ A;  3A0O A;  4OZW A;  4MMI A;  1F9G A;  2WVY A;  3VD5 A;  4J5T A;  4D6D A;  4D6G A;  4F13 A;  4BZE A;  1LUR A;  1JZ8 A;  1N7R A;  3T2Q A;  3I3B A;  1N7O A;  1PX4 A;  1I8Q A;  2JKP A;  1NKG A;  4BZH A;  3WFA A;  1HMU A;  3MV1 1;  1K1W A;  1JZ7 A;  2XHN A;  1JYX A;  2WMF A;  3VSM A;  3IMH A;  4D6H A;  3DYP A;  1X1H A;  2WW1 A;  3BLC A;  1K1X A;  3E1F 1;  1QAZ A;  1F4H A;  4OZV A;  4RNL A;  3E80 A;  4OJZ A;  3DYO A;  5E1Q A;  3VDC A;  3J7H A;  4E1Y A;  1HV6 A;  1NSM A;  1F1S A;  1NS8 A;  4BZG A;  2WVX B;  3VDA A;  1RWH A;  1NSV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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