1N7OA

Streptococcus pneumoniae hyaluronate lyase f343v mutant
Total Genus 259
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
259
sequence length
721
structure length
721
Chain Sequence
b'VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPVKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords hyaluronidase
publication title The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 259
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1n7oA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1n7oA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1n7oA01
1NSXA 2HTAA 4MMIA 1MMZA 2D73A 2E22A 3K25A 2JKAA 1JZ6A 3DECA 3VSNA 2WMHA 3VD7A 1LXKA 2BRWA 1L7KA 2WW0A 3IAQA 3VDAA 3E1F1 2X03A 5A1AA 3OBAA 2CISA 1ULVA 2E24A 2CIRA 2BRPA 1RW9A 3AFLA 1NKGA 4OK2A 1JYNA 2ZXQA 1DP0A 3T08A 4D6HA 3T09A 4DUWA 1OJNA 4OZVA 2WCOA 1PX4A 2WMKA 1JYXA 3T0AA 4FNVA 1K1XA 3DYPA 2CIQA 3BGAA 1K1WA 1K1YA 3ECQA 3NJXA 1JZ4A 2XHNA 1OJOA 2JKPA 1HMUA 1EGUA 2WW2A 3E80A 1NSRA 1JZ8A 2WMFA 3J7HA 4D71A 1NSVA 1YGAA 1I8QA 1OJPA 1NSUA 2WZSA 1X1HA 4F10A 1PX3A 3Q1NA 4E1YA 4D6GA 3MV01 4DUVA 4DUXA 3DCDA 1J0NA 2WMIB 1C82A 4D6DA 4NEIA 1JOVA 1MN0A 1NS0A 4D6FA 1JZ5A 1HM3A 4TTGA 3OB8A 1SNZA 3MV11 3VDCA 1W3YA 2HTBA 4BZHA 3OS7A 1N7RA 1RWGA 4F13A 1JZ7A 2WW3A 2WVXA 5JMFA 1NS2A 4OZWA 3A0OA 3VSMA 4MMHA 3MUZ1 5E1QA 3VD3A 1HV6A 4AQ0A 3I3EA 1QAZA 1OJMA 3IMHA 4D72A 1NSMA 4D6IA 1JYWA 1J0MA 1JYVA 1F4AA 2WDAA 4OJZA 3CZJA 1LOHA 2ZQ0A 1NSSA 3VD9A 1NS4A 1RWAA 2WMGA 1X1IA 2BRVX 3NJVA 2JKEA 3DYMA 3T2OA 4BZEA 1L7JA 1LF9A 2FUQA 3VDBA 1HN1A 2WVZA 3T0DA 4D6EA 1SO0A 3VD5A 3IAPA 1NS8A 3NFVA 1NS7A 3DYOA 1MMYA 1Z45A 1JZ3A 3NREA 3SEPA 3MUY1 1RWFA 2WMJA 3T0BA 3T2PA 1N7PA 3VD4A 2XSGA 4BZFA 1RWHA 3NNBA 3E7JA 4D6JA 3WFAA 1HN0A 1TXKA 1N7NA 2FUTA 1HM2A 1LF6A 1YQ2A 1N7QA 1F9GA 3T2QA 1UG9A 1HMWA 3I3DA 4BZGA 1F1SA 1F4HA 4RNLA 1LURA 1JZ2A 2WVXB 1CB8A 1MMXA 1RWCA 2WVYA 3MWXA 2Q1FA 3I3BA 1N7OA 1X1JA 4D6CA 1LXMA 1MMUA 2WMIA 5JMDA 3A24A 4OK4A 2WW1A 1NSZA
chains in the Genus database with same CATH superfamily
5IL3A 4EV5A 3GT5A 4MMIA 2V8KA 3G4DA 3BS6A 3D4YA 3E33B 5EASA 2CFKA 1V5CA 1JZ6A 3LZ9A 3VD7A 1LXKA 2G0DA 3KSLB 3PQIA 4GTTB 1OACA 2KXSA 2F7OA 2WW0A 3X42A 1IQXA 1GLMA 1TNUB 3M7EA 5GY3A 4FNTA 1FMIA 3OBAA 3SDTA 3S4CA 3DSVB 5ILDA 1N21A 1O6HA 1FBOA 3W7XA 2CIRA 1RW9A 4Z4LA 1W7CA 3RRSA 3T08A 1TF4A 3Q78B 2NVPA 1OJNA 1FPPB 3AMOA 4XUVA 1JYXA 3QRYA 3DYPA 3X41A 3EQAA 2GOXA 3DX2A 2FV0A 5ILKA 3ECQA 3QT3A 1GAHA 3H7LA 2I07B 3KQ4A 2CG0A 2FUZA 1V5DA 2DRQA 5IK9A 2CWVA 3J7HA 2SQCA 2OOVA 5IK0A 2V8IA 4DLQA 1NSUA 1G9GA 3EJSA 3SDUA 1W6CA 4DUXA 1GA2A 3PZ3B 1J0NA 3WIQA 1C82A 3WKHA 4NEIA 2WMIB 3EUVB 1SNZA 2J5CA 2CWUA 1D6YA 1FP3A 1KWFA 3M00A 4Z4JA 3QR8A 3X17A 2XN1A 2Z07A 1N7RA 1O79A 1RWGA 1TNBB 4F13A 3PMMA 3PZ1B 1H13A 3PYAA 3KBTC 1D6ZA 1WMPA 3CZNA 2OQEA 3GLYA 3D51A 5CZLA 1H36A 2CG1A 1UI7A 1OJMA 2RGKA 4ZRQA 1WU6A 1W6GA 1O5MB 1H12A 1XWTA 4D72A 1JYWA 1N4QB 4L6XA 4D6IA 1J0MA 2ALWA 3D5RA 1FAEA 2WDAA 3D5SA 4OJZA 2E2VA 3TY1A 4BTXA 2ZQ0A 1AVLA 1NS4A 1FO2A 2WMGA 2B4FA 1QQFA 3SQCA 3DYMA 2ZISB 1TQSA 1HN1A 4AYOA 3VDBA 3VD5A 3H3KA 1HXGA 3NFVA 1TN6B 1QALA 4AYPA 4MBGB 5FO9B 1NS7A 5DHKA 3X40A 2F7PA 1IQYA 1G87A 4KFEA 3QT9A 3E32B 2WMJA 1G6IA 3WIWA 4Q88A 3T0BA 2JJBA 3DX3A 3VD4A 3ALAA 4FNSA 4BZFA 1KRFA 3NNBA 3N0GA 3E7JA 3HI7A 1HN0A 1GHQA 3WKFA 5ILHA 3SAEA 1HX9A 2WW1A 1AVKA 1CLCA 4DI5A 1XWQA 3M75A 1HMWA 2PNCA 4RNQA 1SQCA 4BZGA 3RJ3A 3K11A 4BOKA 1TN7B 1TQUA 3CZSA 2CWTA 2WVYA 3E37B 2CFWA 2Q1FA 2ZL8A 3A24A 2FBAA 1SPUA 5JMDA 1KSIA 4OK4A 5MEHA 1NSZA 2YFNA 3WIRA 4AYRA 3SDVA 3WKIA 4WU0A 1QAKA 2V3PA 4FNUA 3BVXA 2JKAA 3VSNA 3RX8A 4TF4A 2WMHA 2F7QA 2F6DA 2FYVA 3IAQA 3VDAA 4DLOA 2CISA 4CJ0A 4ZH5A 3M7BA 1GXNA 3AFLA 3E30B 4OK2A 3LVTA 1QBQB 3ACSA 5DHIA 2ZXQA 2W0QA 5IL8A 1IVXA 2YFOA 4DUWA 2D5JA 2YIKA 1N9AB 2WCOA 5CA3A 2WMKA 4D4AA 3W5NA 3BUDA 3MI6A 1K1XA 4D4DA 2CIQA 4EL8A 1WU5A 3RSYA 1HMUA 1EGUA 2H6GB 2D8LA 3W7UA 2WW2A 4L9PB 2WMFA 4FJQA 1D8DB 1EKMA 5FO8B 1W6JA 4L0GA 2CFGA 1AGMA 1X1HA 3DSTB 1N4RB 2DROA 1KZOB 4GTPB 3H2WA 3SDRA 3T0DA 1JOVA 3F59A 4EV2A 3VXDA 4M76A 1HM3A 2EADA 1X81B 3OB8A 3M72A 3EZ8A 3HXFB 2BBCA 4KKJA 2JG0A 1HXKA 3VDCA 3P5RA 2HTBA 3HIGA 2WYIA 1O1SB 2WW3A 1O1TB 4GTMB 1TNOB 2EACA 3CIHA 5JMFA 4C1SA 1NS2A 4GTQB 3A0OA 4OZWA 2OOVC 2BB5A 3BUIA 3MUZ1 3VD3A 3OXUA 4AQ0A 3BVWA 1F9OA 3QG0A 4GTSB 2PN5A 4FXKB 4K3AA 1O6RA 3WA3A 1WMNA 4EHMB 2WINB 1CEMA 3ANIA 3HXCB 3DX1A 1SIHA 1GXMA 2B39A 5AGDA 4BZEA 3KLSA 2XWJB 2FUQA 3UD2A 2WVZA 4D6EA 3VW5A 2CQSA 3E73A 3E6UA 1IU7A 2OQEC 1V7WA 1QWUA 1H14A 5KBPA 2BB6A 2RI9A 4KTPA 3WVFA 2ZIRB 3SEPA 5DGQA 3ANJA 3MUY1 1KFGA 1O6QA 2XSGA 1N4SB 1H3AA 2VN4A 1RWHA 3EJQA 4D6JA 3WFAA 3KSQB 3K7XA 5FOBB 3U7VA 1F9DA 2FUTA 1R76A 3Q79B 1HM2A 3NBBA 3SX1A 1LF6A 3QXFA 1F9GA 2XN0A 2ONHA 3T2QA 4QT9A 3I3DA 4LIXA 3EJTA 4RNLA 3KN4A 2VN7A 1RJOA 3M7LA 4GTOB 1CB8A 2WVXB 1RWCA 3I3BA 3QXQA 1N7OA 1X1JA 1JCQB 4D6CA 1LXMA 1V7XA 2WMIA 1MMUA 1FO3A 3W7WA 1PU4A 4WVAA 4BOJA 2WO0A 3BLBA 2HTAA 1KREA 4GL3A 5IKAA 3X3YA 2E2TA 4JJJA 2D73A 2E22A 1PS3A 1V7VA 3Q7FB 1UI8A 3DECA 3OEDA 4K35A 1KZPB 1DL2A 1HTYA 1L7KA 3Q7AB 4FXGB 3E1F1 2X03A 4D4CA 5A1AA 2F7RA 3AFJA 1KSDA 1AYXA 5IK6A 5CD2A 1H3CA 1H39A 2DRSA 4J5TA 1TQVA 2E24A 4GTRB 1HZFA 2BRPA 5EATA 1QSJA 4V1RA 1QWNA 1NC5A 1JYNA 1SA5B 3QFZA 4GTVB 1N95B 3T09A 4OZVA 1PX4A 1G9JA 2ZZRA 3T0AA 4FNVA 2F0YB 1HCUA 4CE7A 3RX7A 3HIIA 4FNQA 1IA7A 1K1WA 1K1YA 1WU4A 1JZ4A 1W5ZA 4ONTA 3M74A 3QSPA 3QDEA 1HXCA 3M01A 2XN2A 3N0FA 1H35A 1NL4B 3E80A 3EJRA 1NSRA 1TN8B 1KKTA 1FT1B 4Q2BA 1NSVA 3DRAB 1QX1A 3ON6A 2WZSA 3T0UA 4CJ1A 3EU5B 3E34B 2V8JA 4F10A 1PX3A 3Q1NA 1N24A 3CV5A 4D6DA 1JZ5A 1NS0A 4TTGA 3M73A 3QFYA 3MPHA 3MV11 2H6HB 1DCEB 3S4AA 4D4BA 2R2LB 3M78A 1LVNA 2BT3A 2IEJB 3BUPA 3WUXA 3M02A 3BVVA 2WOFA 4D94A 2GZ6A 1LTXB 3KIIA 3PZ2B 1D6UA 2GH4A 4MU9A 3VSMA 5ILIA 1IS9A 4LNVA 1JCRB 1HV6A 1S64B 1QAZA 4KTRA 3WA2X 4D1JA 3PZ4B 3IMHA 4BTWA 4KFDA 1FBWA 3DSUB 5EAUA 1F4AA 3Q73B 3S4BA 1JS4A 1N94B 2CQTA 4GAXA 3AMOB 1RWAA 1X1IA 2BRVX 3NJVA 4WVCA 2JKEA 2XQWA 1LF9A 3IAPA 1O1RB 1NS8A 1LD8B 3C72B 5ILJA 3DSXB 4ZH1A 3SFYB 1Z45A 1IVWA 1JZ3A 3M76A 2WY7A 5E2JA 2E2UA 2F1AA 3T2PA 1N7PA 1SA4B 3P2CA 2EABA 3M77A 1N4PB 3Q75B 3KBUC 1L2AA 1GXOA 1TXKA 2C11A 1N7NA 3DSSB 5M7IA 1HXAA 3RENA 1TQWA 3D50A 1YQ2A 1N7QA 1AV4A 3HXDB 3G6JB 3W5MA 4KFFA 3QPFA 1F4HA 1LURA 1JZ2A 5FO7B 5GZKA 2AHGA 1A2VA 1MMXA 3MWXA 3EJPA 2WOHA 2YX9A 1JZ8A 2PMVA 4LNBB 1N1BA 1N1ZA 3D3IA 4FUSA 1NSXA 1N22A 5ILYA 2D1WA 3G4FA 1VD5A 1MMZA 3K25A 3CU7A 3SDQA 3DX0A 5KKBA 2QNOA 4D1IA 1JRQA 2WGQA 2Y73A 2BRWA 2WY8A 3D52A 2WIIB 4YDEB 1R33A 5GW7A 1L1YA 1RQ5A 1C3DA 1ULVA 5C05A 2A73B 3EU8A 5IKHA 4ZG8A 3DDFA 3DDGA 3BUQA 1NKGA 1K72A 2OKXA 1H54A 3UD1A 1DP0A 4DOEA 4D6HA 1KSCA 1D8EB 1S63B 2A8ZA 4YDOB 1RKYA 3BGAA 1MZCB 1NI1B 3NJXA 1US1A 2XHNA 1OJOA 2JKPA 1H37A 3S4DA 3WC3A 4FNPA 1N20A 1TNYB 4LNGB 4KKIA 2V3NA 3SFXB 4D71A 1HWWA 1YGAA 1I8QA 1N23A 3ACTA 1OJPA 3HXBB 3T33A 1X9DA 2AHFA 3DPYB 3TF4A 1XW2A 4DUVA 1UT9A 1W6KA 2P0VA 4E1YA 1H3BA 4D6GA 1TQTA 3DCDA 3MV01 1MN0A 1GSZA 3SXXA 4D6FA 4TXTA 1TU5A 3QWTA 2EAEA 3WKGA 2JF4A 1W3YA 3LOYA 4BZHA 1WZZA 1O7DD 3NBJA 3OS7A 1R34A 1JZ7A 3BVTA 1NXCA 3M71A 1DYUA 4UFCA 1IVUA 2WVXA 1N9EA 3W7TA 2DRRA 2ONGA 5E1QA 4MMHA 3EJUA 3PGBA 5ILZA 4D8OA 3I3EA 2RI8A 2H6FB 2WYNA 3BUBA 4V1SA 3BVUA 2KXRA 4BTYA 3BLCA 1NSMA 2CFLA 1JYVA 3ANKA 5M7YA 1WMOA 3A3VA 5JPMB 2F1BA 3M7CA 3CZJA 4FNRA 1LOHA 2CFDA 1NSSA 3K5TA 3RX5A 3N9HA 3VD9A 1JCSB 1W2ZA 4ZRPA 2RDYA 3D4ZA 3T2OA 1L7JA 2OW6A 1SO0A 2XFGA 4YCRA 2G02A 3DYOA 1MMYA 3P5PA 1W4NA 2Y74A 2BEDB 3NREA 1FCEA 1RWFA 1TNZB 2H6IB 3PYBA 1SIIA 1KS8A 2NOJA 2C10A 1IA6A 2WYHA 1QAFA 5IM1A 4WVBA 4DODA 1FT2B 1DOGA 3HXEB 5JPNB 1LD7B 1UG9A 2F18A 3X3XA 3DSWB 4AYQA 5DGRA 3S9VA 1F1SA 1UMPA 2FV1A 2AFAA 1IVVA 1GAIA 2XWBB 3X3ZA 3GZKA 2ZBLA 3DX4A 2OW7A 3W7SA
chains in the Genus database with same CATH topology
1NSXA 2HTAA 4MMIA 3BS6A 1MMZA 2D73A 2E22A 3K25A 2JKAA 1JZ6A 3DECA 3VSNA 2WMHA 3VD7A 1LXKA 2BRWA 1L7KA 2WW0A 3IAQA 3VDAA 3E1F1 2X03A 5A1AA 3OBAA 2CISA 1ULVA 4J5TA 2E24A 2CIRA 2BRPA 1RW9A 3AFLA 1NKGA 4OK2A 1JYNA 2ZXQA 1DP0A 3T08A 4D6HA 3T09A 4DUWA 1OJNA 4OZVA 2WCOA 1PX4A 2WMKA 1JYXA 3T0AA 4FNVA 1K1XA 3DYPA 2CIQA 3BGAA 1K1WA 1K1YA 3ECQA 3NJXA 1JZ4A 2XHNA 1OJOA 2JKPA 1HMUA 1EGUA 2WW2A 3E80A 1NSRA 1JZ8A 2WMFA 3J7HA 4D71A 1NSVA 1YGAA 1I8QA 1OJPA 1NSUA 2WZSA 1X1HA 4F10A 1PX3A 3Q1NA 4E1YA 4D6GA 3MV01 4DUVA 4DUXA 3DCDA 1J0NA 2WMIB 1C82A 4D6DA 4NEIA 1JOVA 1MN0A 1NS0A 4D6FA 1JZ5A 1HM3A 4TTGA 3OB8A 1SNZA 3MV11 3VDCA 1W3YA 2HTBA 4BZHA 3OS7A 1N7RA 1RWGA 4F13A 1JZ7A 2WW3A 2WVXA 5JMFA 1NS2A 4OZWA 3A0OA 3VSMA 4MMHA 3MUZ1 5E1QA 3VD3A 1HV6A 4AQ0A 3I3EA 1QAZA 1OJMA 3IMHA 4D72A 3BLCA 1NSMA 4D6IA 1JYWA 1J0MA 1JYVA 1F4AA 2WDAA 4OJZA 3TY1A 3CZJA 1LOHA 2ZQ0A 1NSSA 3VD9A 1NS4A 1RWAA 2WMGA 1X1IA 2BRVX 3NJVA 2JKEA 3DYMA 3T2OA 4BZEA 1L7JA 1LF9A 2FUQA 3VDBA 1HN1A 2WVZA 3T0DA 4D6EA 1SO0A 3VD5A 3IAPA 1NS8A 3NFVA 1NS7A 3DYOA 1MMYA 3WVFA 1Z45A 1JZ3A 3NREA 3SEPA 3MUY1 1RWFA 2WMJA 3T0BA 3T2PA 1N7PA 3VD4A 2XSGA 4BZFA 1RWHA 3NNBA 3E7JA 4D6JA 3WFAA 1HN0A 1TXKA 1N7NA 2FUTA 1HM2A 1LF6A 1YQ2A 1N7QA 1F9GA 3T2QA 1UG9A 1HMWA 3I3DA 4BZGA 1F1SA 1F4HA 4RNLA 1LURA 1JZ2A 2WVXB 1CB8A 1MMXA 1RWCA 2WVYA 3MWXA 2Q1FA 3I3BA 1N7OA 1X1JA 4D6CA 1LXMA 1MMUA 2WMIA 5JMDA 3A24A 4OK4A 2WW1A 1NSZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NSX A;  2HTA A;  4MMI A;  1MMZ A;  2D73 A;  2E22 A;  3K25 A;  2JKA A;  1JZ6 A;  3DEC A;  3VSN A;  2WMH A;  3VD7 A;  1LXK A;  2BRW A;  1L7K A;  2WW0 A;  3IAQ A;  3VDA A;  3E1F 1;  2X03 A;  5A1A A;  3OBA A;  2CIS A;  1ULV A;  2E24 A;  2CIR A;  2BRP A;  1RW9 A;  3AFL A;  1NKG A;  4OK2 A;  1JYN A;  2ZXQ A;  1DP0 A;  3T08 A;  4D6H A;  3T09 A;  4DUW A;  1OJN A;  4OZV A;  2WCO A;  1PX4 A;  2WMK A;  1JYX A;  3T0A A;  4FNV A;  1K1X A;  3DYP A;  2CIQ A;  3BGA A;  1K1W A;  1K1Y A;  3ECQ A;  3NJX A;  1JZ4 A;  2XHN A;  1OJO A;  2JKP A;  1HMU A;  1EGU A;  2WW2 A;  3E80 A;  1NSR A;  1JZ8 A;  2WMF A;  3J7H A;  4D71 A;  1NSV A;  1YGA A;  1I8Q A;  1OJP A;  1NSU A;  2WZS A;  1X1H A;  4F10 A;  1PX3 A;  3Q1N A;  4E1Y A;  4D6G A;  3MV0 1;  4DUV A;  4DUX A;  3DCD A;  1J0N A;  2WMI B;  1C82 A;  4D6D A;  4NEI A;  1JOV A;  1MN0 A;  1NS0 A;  4D6F A;  1JZ5 A;  1HM3 A;  4TTG A;  3OB8 A;  1SNZ A;  3MV1 1;  3VDC A;  1W3Y A;  2HTB A;  4BZH A;  3OS7 A;  1N7R A;  1RWG A;  4F13 A;  1JZ7 A;  2WW3 A;  2WVX A;  5JMF A;  1NS2 A;  4OZW A;  3A0O A;  3VSM A;  4MMH A;  3MUZ 1;  5E1Q A;  3VD3 A;  1HV6 A;  4AQ0 A;  3I3E A;  1QAZ A;  1OJM A;  3IMH A;  4D72 A;  1NSM A;  4D6I A;  1JYW A;  1J0M A;  1JYV A;  1F4A A;  2WDA A;  4OJZ A;  3CZJ A;  1LOH A;  2ZQ0 A;  1NSS A;  3VD9 A;  1NS4 A;  1RWA A;  2WMG A;  1X1I A;  2BRV X;  3NJV A;  2JKE A;  3DYM A;  3T2O A;  4BZE A;  1L7J A;  1LF9 A;  2FUQ A;  3VDB A;  1HN1 A;  2WVZ A;  3T0D A;  4D6E A;  1SO0 A;  3VD5 A;  3IAP A;  1NS8 A;  3NFV A;  1NS7 A;  3DYO A;  1MMY A;  1Z45 A;  1JZ3 A;  3NRE A;  3SEP A;  3MUY 1;  1RWF A;  2WMJ A;  3T0B A;  3T2P A;  1N7P A;  3VD4 A;  2XSG A;  4BZF A;  1RWH A;  3NNB A;  3E7J A;  4D6J A;  3WFA A;  1HN0 A;  1TXK A;  1N7N A;  2FUT A;  1HM2 A;  1LF6 A;  1YQ2 A;  1N7Q A;  1F9G A;  3T2Q A;  1UG9 A;  1HMW A;  3I3D A;  4BZG A;  1F1S A;  1F4H A;  4RNL A;  1LUR A;  1JZ2 A;  2WVX B;  1CB8 A;  1MMX A;  1RWC A;  2WVY A;  3MWX A;  2Q1F A;  3I3B A;  1N7O A;  1X1J A;  4D6C A;  1LXM A;  1MMU A;  2WMI A;  5JMD A;  3A24 A;  4OK4 A;  2WW1 A;  1NSZ A; 
#chains in the Genus database with same CATH topology
 5IL3 A;  4EV5 A;  3GT5 A;  4MMI A;  2V8K A;  3G4D A;  3BS6 A;  3D4Y A;  3E33 B;  5EAS A;  2CFK A;  1V5C A;  1JZ6 A;  3LZ9 A;  3VD7 A;  1LXK A;  2G0D A;  3KSL B;  3PQI A;  4GTT B;  1OAC A;  2KXS A;  2F7O A;  2WW0 A;  3X42 A;  1IQX A;  1GLM A;  1TNU B;  3M7E A;  5GY3 A;  4FNT A;  1FMI A;  3OBA A;  3SDT A;  3S4C A;  3DSV B;  5ILD A;  1N21 A;  1O6H A;  1FBO A;  3W7X A;  2CIR A;  1RW9 A;  4Z4L A;  1W7C A;  3RRS A;  3T08 A;  1TF4 A;  3Q78 B;  2NVP A;  1OJN A;  1FPP B;  3AMO A;  4XUV A;  1JYX A;  3QRY A;  3DYP A;  3X41 A;  3EQA A;  2GOX A;  3DX2 A;  2FV0 A;  5ILK A;  3ECQ A;  3QT3 A;  1GAH A;  3H7L A;  2I07 B;  3KQ4 A;  2CG0 A;  2FUZ A;  1V5D A;  2DRQ A;  5IK9 A;  2CWV A;  3J7H A;  2SQC A;  2OOV A;  5IK0 A;  2V8I A;  4DLQ A;  1NSU A;  1G9G A;  3EJS A;  3SDU A;  1W6C A;  4DUX A;  1GA2 A;  3PZ3 B;  1J0N A;  3WIQ A;  1C82 A;  3WKH A;  4NEI A;  2WMI B;  3EUV B;  1SNZ A;  2J5C A;  2CWU A;  1D6Y A;  1FP3 A;  1KWF A;  3M00 A;  4Z4J A;  3QR8 A;  3X17 A;  2XN1 A;  2Z07 A;  1N7R A;  1O79 A;  1RWG A;  1TNB B;  4F13 A;  3PMM A;  3PZ1 B;  1H13 A;  3PYA A;  3KBT C;  1D6Z A;  1WMP A;  3CZN A;  2OQE A;  3GLY A;  3D51 A;  5CZL A;  1H36 A;  2CG1 A;  1UI7 A;  1OJM A;  2RGK A;  4ZRQ A;  1WU6 A;  1W6G A;  1O5M B;  1H12 A;  1XWT A;  4D72 A;  1JYW A;  1N4Q B;  4L6X A;  4D6I A;  1J0M A;  2ALW A;  3D5R A;  1FAE A;  2WDA A;  3D5S A;  4OJZ A;  2E2V A;  3TY1 A;  4BTX A;  2ZQ0 A;  1AVL A;  1NS4 A;  1FO2 A;  2WMG A;  2B4F A;  1QQF A;  3SQC A;  3DYM A;  2ZIS B;  1TQS A;  1HN1 A;  4AYO A;  3VDB A;  3VD5 A;  3H3K A;  1HXG A;  3NFV A;  1TN6 B;  1QAL A;  4AYP A;  4MBG B;  5FO9 B;  1NS7 A;  5DHK A;  3X40 A;  2F7P A;  1IQY A;  1G87 A;  4KFE A;  3QT9 A;  3E32 B;  2WMJ A;  1G6I A;  3WIW A;  4Q88 A;  3T0B A;  2JJB A;  3DX3 A;  3VD4 A;  3ALA A;  4FNS A;  4BZF A;  1KRF A;  3NNB A;  3N0G A;  3E7J A;  3HI7 A;  1HN0 A;  1GHQ A;  3WKF A;  5ILH A;  3SAE A;  1HX9 A;  2WW1 A;  1AVK A;  1CLC A;  4DI5 A;  1XWQ A;  3M75 A;  1HMW A;  2PNC A;  4RNQ A;  1SQC A;  4BZG A;  3RJ3 A;  3K11 A;  4BOK A;  1TN7 B;  1TQU A;  3CZS A;  2CWT A;  2WVY A;  3E37 B;  2CFW A;  2Q1F A;  2ZL8 A;  3A24 A;  2FBA A;  1SPU A;  5JMD A;  1KSI A;  4OK4 A;  5MEH A;  1NSZ A;  2YFN A;  3WIR A;  4AYR A;  3SDV A;  3WKI A;  4WU0 A;  1QAK A;  2V3P A;  4FNU A;  3BVX A;  2JKA A;  3VSN A;  3RX8 A;  4TF4 A;  2WMH A;  2F7Q A;  2F6D A;  2FYV A;  3IAQ A;  3VDA A;  4DLO A;  2CIS A;  4CJ0 A;  4ZH5 A;  3M7B A;  1GXN A;  3AFL A;  3E30 B;  4OK2 A;  3LVT A;  1QBQ B;  3ACS A;  5DHI A;  2ZXQ A;  2W0Q A;  5IL8 A;  1IVX A;  2YFO A;  4DUW A;  2D5J A;  2YIK A;  1N9A B;  2WCO A;  5CA3 A;  2WMK A;  4D4A A;  3W5N A;  3BUD A;  3MI6 A;  1K1X A;  4D4D A;  2CIQ A;  4EL8 A;  1WU5 A;  3RSY A;  1HMU A;  1EGU A;  2H6G B;  2D8L A;  3W7U A;  2WW2 A;  4L9P B;  2WMF A;  4FJQ A;  1D8D B;  1EKM A;  5FO8 B;  1W6J A;  4L0G A;  2CFG A;  1AGM A;  1X1H A;  3DST B;  1N4R B;  2DRO A;  1KZO B;  4GTP B;  3H2W A;  3SDR A;  3T0D A;  1JOV A;  3F59 A;  4EV2 A;  3VXD A;  4M76 A;  1HM3 A;  2EAD A;  1X81 B;  3OB8 A;  3M72 A;  3EZ8 A;  3HXF B;  2BBC A;  4KKJ A;  2JG0 A;  1HXK A;  3VDC A;  3P5R A;  2HTB A;  3HIG A;  2WYI A;  1O1S B;  2WW3 A;  1O1T B;  4GTM B;  1TNO B;  2EAC A;  3CIH A;  5JMF A;  4C1S A;  1NS2 A;  4GTQ B;  3A0O A;  4OZW A;  2OOV C;  2BB5 A;  3BUI A;  3MUZ 1;  3VD3 A;  3OXU A;  4AQ0 A;  3BVW A;  1F9O A;  3QG0 A;  4GTS B;  2PN5 A;  4FXK B;  4K3A A;  1O6R A;  3WA3 A;  1WMN A;  4EHM B;  2WIN B;  1CEM A;  3ANI A;  3HXC B;  3DX1 A;  1SIH A;  1GXM A;  2B39 A;  5AGD A;  4BZE A;  3KLS A;  2XWJ B;  2FUQ A;  3UD2 A;  2WVZ A;  4D6E A;  3VW5 A;  2CQS A;  3E73 A;  3E6U A;  1IU7 A;  2OQE C;  1V7W A;  1QWU A;  1H14 A;  5KBP A;  2BB6 A;  2RI9 A;  4KTP A;  3WVF A;  2ZIR B;  3SEP A;  5DGQ A;  3ANJ A;  3MUY 1;  1KFG A;  1O6Q A;  2XSG A;  1N4S B;  1H3A A;  2VN4 A;  1RWH A;  3EJQ A;  4D6J A;  3WFA A;  3KSQ B;  3K7X A;  5FOB B;  3U7V A;  1F9D A;  2FUT A;  1R76 A;  3Q79 B;  1HM2 A;  3NBB A;  3SX1 A;  1LF6 A;  3QXF A;  1F9G A;  2XN0 A;  2ONH A;  3T2Q A;  4QT9 A;  3I3D A;  4LIX A;  3EJT A;  4RNL A;  3KN4 A;  2VN7 A;  1RJO A;  3M7L A;  4GTO B;  1CB8 A;  2WVX B;  1RWC A;  3I3B A;  3QXQ A;  1N7O A;  1X1J A;  1JCQ B;  4D6C A;  1LXM A;  1V7X A;  2WMI A;  1MMU A;  1FO3 A;  3W7W A;  1PU4 A;  4WVA A;  4BOJ A;  2WO0 A;  3BLB A;  2HTA A;  1KRE A;  4GL3 A;  5IKA A;  3X3Y A;  2E2T A;  4JJJ A;  2D73 A;  2E22 A;  1PS3 A;  1V7V A;  3Q7F B;  1UI8 A;  3DEC A;  3OED A;  4K35 A;  1KZP B;  1DL2 A;  1HTY A;  1L7K A;  3Q7A B;  4FXG B;  3E1F 1;  2X03 A;  4D4C A;  5A1A A;  2F7R A;  3AFJ A;  1KSD A;  1AYX A;  5IK6 A;  5CD2 A;  1H3C A;  1H39 A;  2DRS A;  4J5T A;  1TQV A;  2E24 A;  4GTR B;  1HZF A;  2BRP A;  5EAT A;  1QSJ A;  4V1R A;  1QWN A;  1NC5 A;  1JYN A;  1SA5 B;  3QFZ A;  4GTV B;  1N95 B;  3T09 A;  4OZV A;  1PX4 A;  1G9J A;  2ZZR A;  3T0A A;  4FNV A;  2F0Y B;  1HCU A;  4CE7 A;  3RX7 A;  3HII A;  4FNQ A;  1IA7 A;  1K1W A;  1K1Y A;  1WU4 A;  1JZ4 A;  1W5Z A;  4ONT A;  3M74 A;  3QSP A;  3QDE A;  1HXC A;  3M01 A;  2XN2 A;  3N0F A;  1H35 A;  1NL4 B;  3E80 A;  3EJR A;  1NSR A;  1TN8 B;  1KKT A;  1FT1 B;  4Q2B A;  1NSV A;  3DRA B;  1QX1 A;  3ON6 A;  2WZS A;  3T0U A;  4CJ1 A;  3EU5 B;  3E34 B;  2V8J A;  4F10 A;  1PX3 A;  3Q1N A;  1N24 A;  3CV5 A;  4D6D A;  1JZ5 A;  1NS0 A;  4TTG A;  3M73 A;  3QFY A;  3MPH A;  3MV1 1;  2H6H B;  1DCE B;  3S4A A;  4D4B A;  2R2L B;  3M78 A;  1LVN A;  2BT3 A;  2IEJ B;  3BUP A;  3WUX A;  3M02 A;  3BVV A;  2WOF A;  4D94 A;  2GZ6 A;  1LTX B;  3KII A;  3PZ2 B;  1D6U A;  2GH4 A;  4MU9 A;  3VSM A;  5ILI A;  1IS9 A;  4LNV A;  1JCR B;  1HV6 A;  1S64 B;  1QAZ A;  4KTR A;  3WA2 X;  4D1J A;  3PZ4 B;  3IMH A;  4BTW A;  4KFD A;  1FBW A;  3DSU B;  5EAU A;  1F4A A;  3Q73 B;  3S4B A;  1JS4 A;  1N94 B;  2CQT A;  4GAX A;  3AMO B;  1RWA A;  1X1I A;  2BRV X;  3NJV A;  4WVC A;  2JKE A;  2XQW A;  1LF9 A;  3IAP A;  1O1R B;  1NS8 A;  1LD8 B;  3C72 B;  5ILJ A;  3DSX B;  4ZH1 A;  3SFY B;  1Z45 A;  1IVW A;  1JZ3 A;  3M76 A;  2WY7 A;  5E2J A;  2E2U A;  2F1A A;  3T2P A;  1N7P A;  1SA4 B;  3P2C A;  2EAB A;  3M77 A;  1N4P B;  3Q75 B;  3KBU C;  1L2A A;  1GXO A;  1TXK A;  2C11 A;  1N7N A;  3DSS B;  5M7I A;  1HXA A;  3REN A;  1TQW A;  3D50 A;  1YQ2 A;  1N7Q A;  1AV4 A;  3HXD B;  3G6J B;  3W5M A;  4KFF A;  3QPF A;  1F4H A;  1LUR A;  1JZ2 A;  5FO7 B;  5GZK A;  2AHG A;  1A2V A;  1MMX A;  3MWX A;  3EJP A;  2WOH A;  2YX9 A;  1JZ8 A;  2PMV A;  4LNB B;  1N1B A;  1N1Z A;  3D3I A;  4FUS A;  1NSX A;  1N22 A;  5ILY A;  2D1W A;  3G4F A;  1VD5 A;  1MMZ A;  3K25 A;  3CU7 A;  3SDQ A;  3DX0 A;  5KKB A;  2QNO A;  4D1I A;  1JRQ A;  2WGQ A;  2Y73 A;  2BRW A;  2WY8 A;  3D52 A;  2WII B;  4YDE B;  1R33 A;  5GW7 A;  1L1Y A;  1RQ5 A;  1C3D A;  1ULV A;  5C05 A;  2A73 B;  3EU8 A;  5IKH A;  4ZG8 A;  3DDF A;  3DDG A;  3BUQ A;  1NKG A;  1K72 A;  2OKX A;  1H54 A;  3UD1 A;  1DP0 A;  4DOE A;  4D6H A;  1KSC A;  1D8E B;  1S63 B;  2A8Z A;  4YDO B;  1RKY A;  3BGA A;  1MZC B;  1NI1 B;  3NJX A;  1US1 A;  2XHN A;  1OJO A;  2JKP A;  1H37 A;  3S4D A;  3WC3 A;  4FNP A;  1N20 A;  1TNY B;  4LNG B;  4KKI A;  2V3N A;  3SFX B;  4D71 A;  1HWW A;  1YGA A;  1I8Q A;  1N23 A;  3ACT A;  1OJP A;  3HXB B;  3T33 A;  1X9D A;  2AHF A;  3DPY B;  3TF4 A;  1XW2 A;  4DUV A;  1UT9 A;  1W6K A;  2P0V A;  4E1Y A;  1H3B A;  4D6G A;  1TQT A;  3DCD A;  3MV0 1;  1MN0 A;  1GSZ A;  3SXX A;  4D6F A;  4TXT A;  1TU5 A;  3QWT A;  2EAE A;  3WKG A;  2JF4 A;  1W3Y A;  3LOY A;  4BZH A;  1WZZ A;  1O7D D;  3NBJ A;  3OS7 A;  1R34 A;  1JZ7 A;  3BVT A;  1NXC A;  3M71 A;  1DYU A;  4UFC A;  1IVU A;  2WVX A;  1N9E A;  3W7T A;  2DRR A;  2ONG A;  5E1Q A;  4MMH A;  3EJU A;  3PGB A;  5ILZ A;  4D8O A;  3I3E A;  2RI8 A;  2H6F B;  2WYN A;  3BUB A;  4V1S A;  3BVU A;  2KXR A;  4BTY A;  3BLC A;  1NSM A;  2CFL A;  1JYV A;  3ANK A;  5M7Y A;  1WMO A;  3A3V A;  5JPM B;  2F1B A;  3M7C A;  3CZJ A;  4FNR A;  1LOH A;  2CFD A;  1NSS A;  3K5T A;  3RX5 A;  3N9H A;  3VD9 A;  1JCS B;  1W2Z A;  4ZRP A;  2RDY A;  3D4Z A;  3T2O A;  1L7J A;  2OW6 A;  1SO0 A;  2XFG A;  4YCR A;  2G02 A;  3DYO A;  1MMY A;  3P5P A;  1W4N A;  2Y74 A;  2BED B;  3NRE A;  1FCE A;  1RWF A;  1TNZ B;  2H6I B;  3PYB A;  1SII A;  1KS8 A;  2NOJ A;  2C10 A;  1IA6 A;  2WYH A;  1QAF A;  5IM1 A;  4WVB A;  4DOD A;  1FT2 B;  1DOG A;  3HXE B;  5JPN B;  1LD7 B;  1UG9 A;  2F18 A;  3X3X A;  3DSW B;  4AYQ A;  5DGR A;  3S9V A;  1F1S A;  1UMP A;  2FV1 A;  2AFA A;  1IVV A;  1GAI A;  2XWB B;  3X3Z A;  3GZK A;  2ZBL A;  3DX4 A;  2OW7 A;  3W7S A; 
#chains in the Genus database with same CATH homology
 1NSX A;  2HTA A;  4MMI A;  3BS6 A;  1MMZ A;  2D73 A;  2E22 A;  3K25 A;  2JKA A;  1JZ6 A;  3DEC A;  3VSN A;  2WMH A;  3VD7 A;  1LXK A;  2BRW A;  1L7K A;  2WW0 A;  3IAQ A;  3VDA A;  3E1F 1;  2X03 A;  5A1A A;  3OBA A;  2CIS A;  1ULV A;  4J5T A;  2E24 A;  2CIR A;  2BRP A;  1RW9 A;  3AFL A;  1NKG A;  4OK2 A;  1JYN A;  2ZXQ A;  1DP0 A;  3T08 A;  4D6H A;  3T09 A;  4DUW A;  1OJN A;  4OZV A;  2WCO A;  1PX4 A;  2WMK A;  1JYX A;  3T0A A;  4FNV A;  1K1X A;  3DYP A;  2CIQ A;  3BGA A;  1K1W A;  1K1Y A;  3ECQ A;  3NJX A;  1JZ4 A;  2XHN A;  1OJO A;  2JKP A;  1HMU A;  1EGU A;  2WW2 A;  3E80 A;  1NSR A;  1JZ8 A;  2WMF A;  3J7H A;  4D71 A;  1NSV A;  1YGA A;  1I8Q A;  1OJP A;  1NSU A;  2WZS A;  1X1H A;  4F10 A;  1PX3 A;  3Q1N A;  4E1Y A;  4D6G A;  3MV0 1;  4DUV A;  4DUX A;  3DCD A;  1J0N A;  2WMI B;  1C82 A;  4D6D A;  4NEI A;  1JOV A;  1MN0 A;  1NS0 A;  4D6F A;  1JZ5 A;  1HM3 A;  4TTG A;  3OB8 A;  1SNZ A;  3MV1 1;  3VDC A;  1W3Y A;  2HTB A;  4BZH A;  3OS7 A;  1N7R A;  1RWG A;  4F13 A;  1JZ7 A;  2WW3 A;  2WVX A;  5JMF A;  1NS2 A;  4OZW A;  3A0O A;  3VSM A;  4MMH A;  3MUZ 1;  5E1Q A;  3VD3 A;  1HV6 A;  4AQ0 A;  3I3E A;  1QAZ A;  1OJM A;  3IMH A;  4D72 A;  3BLC A;  1NSM A;  4D6I A;  1JYW A;  1J0M A;  1JYV A;  1F4A A;  2WDA A;  4OJZ A;  3TY1 A;  3CZJ A;  1LOH A;  2ZQ0 A;  1NSS A;  3VD9 A;  1NS4 A;  1RWA A;  2WMG A;  1X1I A;  2BRV X;  3NJV A;  2JKE A;  3DYM A;  3T2O A;  4BZE A;  1L7J A;  1LF9 A;  2FUQ A;  3VDB A;  1HN1 A;  2WVZ A;  3T0D A;  4D6E A;  1SO0 A;  3VD5 A;  3IAP A;  1NS8 A;  3NFV A;  1NS7 A;  3DYO A;  1MMY A;  3WVF A;  1Z45 A;  1JZ3 A;  3NRE A;  3SEP A;  3MUY 1;  1RWF A;  2WMJ A;  3T0B A;  3T2P A;  1N7P A;  3VD4 A;  2XSG A;  4BZF A;  1RWH A;  3NNB A;  3E7J A;  4D6J A;  3WFA A;  1HN0 A;  1TXK A;  1N7N A;  2FUT A;  1HM2 A;  1LF6 A;  1YQ2 A;  1N7Q A;  1F9G A;  3T2Q A;  1UG9 A;  1HMW A;  3I3D A;  4BZG A;  1F1S A;  1F4H A;  4RNL A;  1LUR A;  1JZ2 A;  2WVX B;  1CB8 A;  1MMX A;  1RWC A;  2WVY A;  3MWX A;  2Q1F A;  3I3B A;  1N7O A;  1X1J A;  4D6C A;  1LXM A;  1MMU A;  2WMI A;  5JMD A;  3A24 A;  4OK4 A;  2WW1 A;  1NSZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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