1RWFA

Crystal structure of arthrobacter aurescens chondroitin ac lyase in complex with chondroitin tetrasaccharide
Total Genus 260
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
260
sequence length
754
structure length
754
Chain Sequence
PGAAEFAALRNRWVDQITGRNVIQAGDPDFAKAITALNNKAADSLAKLDAAAGRTSVFTDLSLAKDAEMVTTYTRLSQLATAWATPTAAVFGDAAVLAAIKAGLADANTLCYNDRKEEVGNWWSWEIGVPRALADAMVLLHAELSAAERTAYCAAIDHFVPDPWLQFPPKRGKITSVGANRVDLCQGIIIRSLAGEDPTKLNHAVAGLSQVWQYVTSGDGIFRDGSFIQHSTTPYTGSYGVVLLTGLSKLFSLLGGTAFEVSDPTRSIFFDAVEGSFAPVMINGAMADAVRGRSISREANTGYDLGASAIEAILLLARAMDPATAARWRGLCAGWIARDTYRPILNSASVPRTALVKQLEATGVAPVAEATGHKLFPAMDRTMHRGPGWALSLALSSNRIAWYECGNGENNRGYHTGSGMTYFYTSDLGQYDDAFWATANYNRLPGITVDTTPLPDKVEGQWGAAVPADEWSGATALGEVAAVGQHLVGPGRTGLTARKSWFVSGDVTVCLGADISTASGAKVETIVDHRNLHQGSNTLTTAAGTIAGTAGTVEVLGDGRWVHLEGFGGYAMLDDSPLHVLRETRSGSWSGVNINGSATVQQRNFATLYVNHGVGPVAGSYAYMVAPGASVDLTRKLLEGNKYSVIRNDATAQSVEFKTAKTTAATFWKPGMAGDLGASGPACVVFSRHGNELSLAVSEPTQKAAGLTLTLPEGTWSSVLEGAGTLGTDADGRSTLTLDTTGLSGKTKLIKLKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords chondroitin AC lyase
publication title High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism
pubmed doi rcsb
total genus 260
structure length 754
sequence length 754
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2003-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1rwfA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1rwfA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1rwfA02
1TXKA 2WVXA 1Z45A 1C82A 2JKPA 3VD5A 1LOHA 4D6HA 1NSUA 3J7HA 3A24A 3DYPA 3IAPA 1RWFA 3NREA 2BRVX 1F4AA 3OB8A 2Q1FA 1NSRA 2D73A 1OJPA 4BZGA 1JYXA 1DP0A 3I3BA 1N7RA 3VD9A 2WW2A 3MUY1 3T0DA 2XHNA 4AQ0A 2X03A 1NSVA 1NKGA 1NS8A 3MV11 3T2OA 2FUQA 2BRWA 2WW1A 2WZSA 2FUTA 3DECA 2HTAA 3DCDA 1J0MA 1HN0A 1JYWA 5A1AA 1RWHA 4D6EA 3I3EA 3T2PA 1HMWA 1SO0A 3ECQA 4OK2A 3IMHA 3CZJA 1HN1A 4BZEA 3NJVA 1N7OA 4F13A 3DYOA 1K1WA 4D6GA 3E7JA 3NJXA 4OZWA 1K1YA 1MMUA 1LXKA 2WMJA 1F9GA 2WMHA 1LURA 4D72A 2WVXB 1F1SA 4RNLA 4D6CA 3SEPA 2WMIA 1LF9A 1YQ2A 1JZ4A 1JZ6A 1NSZA 1RWGA 1NS2A 3E80A 2HTBA 3VD7A 3E1F1 1HMUA 1L7JA 1SNZA 3Q1NA 1EGUA 1X1HA 4FNVA 2JKAA 3VDBA 2CIQA 3NNBA 3MUZ1 2WCOA 5JMDA 1LF6A 1PX3A 1ULVA 3IAQA 1JZ2A 4BZFA 3OS7A 4DUVA 1RW9A 1JZ8A 1OJMA 4MMHA 4D6JA 2ZXQA 1JZ7A 3A0OA 1MMYA 2BRPA 5E1QA 1X1JA 2ZQ0A 3T09A 1X1IA 1RWCA 1NSSA 3MWXA 3K25A 3T0AA 1JYVA 3VDCA 3VSMA 1LXMA 2WMGA 4D71A 1NS4A 3DYMA 1NS7A 2WMIB 1CB8A 2WVYA 3VD3A 1QAZA 3MV01 1L7KA 3BGAA 5JMFA 1JOVA 4D6FA 1NSXA 3VDAA 3WFAA 2WMFA 2WW0A 1YGAA 4DUXA 4TTGA 1N7QA 1W3YA 4BZHA 1OJOA 1NS0A 3I3DA 1I8QA 1HM3A 1PX4A 2CISA 1OJNA 2WDAA 3NFVA 2WMKA 1MMXA 4DUWA 1HV6A 3T2QA 1N7PA 2XSGA 4OK4A 1N7NA 4OZVA 1K1XA 1J0NA 1NSMA 1JZ3A 1RWAA 2JKEA 3AFLA 2WVZA 2E24A 4NEIA 4D6DA 3VSNA 1JYNA 4E1YA 4OJZA 1HM2A 3VD4A 1UG9A 4D6IA 3OBAA 3T08A 3T0BA 2WW3A 4F10A 1MN0A 2CIRA 1JZ5A 1F4HA 2E22A 1MMZA 4MMIA
chains in the Genus database with same CATH superfamily
1TXKA 2WVXA 1H13A 5E2JA 3WC3A 1W6JA 3NREA 5EATA 3S4BA 3DYPA 1RWFA 1NI1B 4D1JA 2D5JA 2BT3A 2F7PA 3M7CA 3OB8A 3RX7A 2KXSA 1OJPA 1F9DA 3PZ4B 4D94A 3KN4A 5KBPA 1N7RA 1UI7A 3QDEA 3WIQA 3TY1A 5MEHA 3W5NA 2OW6A 5EASA 3DDGA 3SDUA 2F7RA 3OEDA 1TN6B 4LNGB 1NKGA 2YFNA 3QR8A 2FUQA 3M7LA 2WZSA 4GTVB 1TQVA 4WVBA 3KBTC 1HTYA 2AHGA 4EV5A 5A1AA 1RWHA 2DROA 3W7TA 4DLOA 3ON6A 3Q7AB 3WIWA 3W7UA 3CZJA 4F13A 3M7BA 1GXMA 3DYOA 1K1WA 1LD7B 1V5DA 2D8LA 3E7JA 4L6XA 4OZWA 3M72A 1K1YA 3NJXA 1H3AA 2WVXB 3QRYA 1F1SA 3S9VA 2C11A 2JJBA 2WMIA 2CFWA 1TQTA 1JZ4A 1CLCA 1NSZA 1JZ6A 2E2UA 2FV1A 1RWGA 2CFLA 1XWQA 3SDQA 2YIKA 3D51A 3DX2A 3M71A 5M7YA 1D8EB 5CZLA 3SAEA 5IK9A 2JG0A 4ZG8A 5KKBA 2FYVA 3MI6A 3QXFA 5C05A 3Q78B 3KIIA 3SXXA 3NNBA 2WCOA 4KTPA 1WZZA 3EQAA 3BLBA 1SA4B 1PX3A 2ALWA 1D6UA 1TN7B 4Z4LA 4AYPA 3IAQA 4D1IA 3WVFA 1JZ2A 3S4DA 3RX5A 4DUVA 2FV0A 4FXKB 4KKIA 1N4SB 1C3DA 2AFAA 3VW5A 1H3CA 4C1SA 1KZPB 1N23A 3C72B 1K72A 1KFGA 1N9EA 2V3NA 1H35A 5ILZA 3EU5B 1US1A 3BUIA 2NVPA 4BOKA 3E32B 2WMIB 3RSYA 2WOFA 3MV01 1S63B 3K11A 3DX3A 5JMFA 4EV2A 3P5RA 1TNBB 3OXUA 2WMFA 1SA5B 1OJOA 1HXKA 3M74A 3EJUA 1HM3A 1O79A 1H3BA 4EL8A 3NBJA 1QSJA 3ACTA 1HXGA 2W0QA 1KS8A 4D4DA 4WU0A 3M00A 3PYAA 2IEJB 1UI8A 2WYHA 1D8DB 3W7SA 1QBQB 3EJQA 4OZVA 2CQTA 3X42A 1RWAA 5IKHA 2D1WA 2CWVA 4D4BA 2WINB 5GW7A 4BOJA 3RRSA 3CZNA 4D6DA 3WA2X 3RJ3A 1JYNA 5IL3A 5ILYA 2F7OA 1HM2A 3UD1A 2XFGA 4ZRPA 2FBAA 1FAEA 3AMOA 1JZ5A 1KKTA 2JF4A 5M7IA 1IVUA 2E22A 1SIHA 3AFJA 2Y73A 3WKIA 2CG0A 3S4CA 3VD5A 1LOHA 1H14A 1NSUA 3A24A 3IAPA 2C10A 2CG1A 4BTXA 2Q1FA 4V1RA 1NSRA 2D73A 3PYBA 2PN5A 4BZGA 3NBBA 3D52A 4D4AA 2F18A 3VD9A 3T0DA 2A8ZA 1H12A 3CV5A 1N95B 1N4RB 3DSUB 4LIXA 1QX1A 2GZ6A 2V8KA 1HZFA 1W6KA 1NSVA 1NS8A 3DX1A 3MV11 3Q75B 3SFXB 1IVVA 3DECA 4GL3A 3DCDA 1HWWA 1J0MA 1IS9A 4AYOA 3D4YA 3T2PA 1HMWA 5CA3A 4OK2A 3EJTA 1HN1A 4JJJA 3HI7A 1N7OA 3S4AA 5JPMB 4XUVA 2H6GB 1IA7A 3AMOB 4L9PB 1F9GA 3HXFB 4GAXA 1IQXA 5IK6A 1DL2A 1N22A 1MZCB 2J5CA 2NOJA 4FNPA 4RNLA 4D6CA 1SPUA 1W2ZA 1HXCA 1YQ2A 4WVAA 1IVXA 1PU4A 2CFGA 3P2CA 1FO2A 1NS2A 2V3PA 3H7LA 4Z4JA 1HXAA 3VD7A 2F0YB 2EAEA 2KXRA 1RJOA 1SNZA 2CWUA 3G4DA 3M01A 3SFYB 3PQIA 3K5TA 1O6QA 1N24A 1X1HA 2JKAA 3BVTA 3ANJA 5ILDA 4ZRQA 1LF6A 3LZ9A 1ULVA 1XWTA 3HXDB 4FNQA 2BB6A 5GY3A 3E34B 4BZFA 3DX0A 1TNYB 1TNUB 3WKGA 4DOEA 1MMYA 5E1QA 3EZ8A 2WY7A 1X1IA 4L0GA 3EU8A 3D4ZA 2V8IA 2WMGA 3M75A 2GH4A 1NS4A 3DYMA 3KQ4A 4EHMB 1CB8A 2WVYA 3BS6A 4CJ0A 1L7KA 1KZOB 1NSXA 4D6FA 1G9GA 3VDAA 4DUXA 4UFCA 4TTGA 2OKXA 1W3YA 1NS0A 2OOVA 5GZKA 1WU6A 1AVLA 1X9DA 1S64B 1TNZB 2WDAA 2WMKA 4D8OA 3E30B 1HV6A 3CIHA 3T2QA 5DGQA 2GOXA 2XSGA 3WA3A 3UD2A 1J0NA 1GXNA 4GTTB 2JKEA 2DRRA 3N0FA 3G4FA 4KKJA 2WVZA 3X17A 1AVKA 1JRQA 2ZBLA 3VSNA 1AYXA 3DSSB 4E1YA 2G02A 2RDYA 1TU5A 2ONGA 3M7EA 1UG9A 2ZIRB 3OBAA 3T08A 3SDVA 2CWTA 3W7WA 3T0BA 2WGQA 3D3IA 1D6ZA 2VN4A 1N94B 3N0GA 1KSIA 1QWNA 5FO9B 4MMIA 1TNOB 1DOGA 1Z45A 1C82A 3WKHA 2JKPA 1G9JA 3PZ3B 2WYIA 5FO7B 4D6HA 2V8JA 1WMOA 3SDTA 3T0UA 1F4AA 3GZKA 1XW2A 1IQYA 1W4NA 2WW2A 3BVXA 1QQFA 1HCUA 1V7WA 5JPNB 4AQ0A 4ONTA 1NL4B 2X03A 3W5MA 3M76A 5DHIA 1SQCA 2BRWA 1OACA 2PNCA 2WW1A 1GAIA 4ZH1A 1HN0A 1JYWA 3M77A 1O7DD 3I3EA 4QT9A 3LVTA 1JCSB 2XN1A 1TQSA 1G87A 1N9AB 3NJVA 2RI8A 1KREA 1FO3A 2BBCA 1VD5A 4GTSB 1MMUA 1W5ZA 2WMJA 2WMHA 2RGKA 1LURA 3X3XA 4D72A 2RI9A 1IU7A 2H6HB 5DHKA 3QXQA 1WU5A 1FMIA 1L2AA 3SEPA 2BEDB 3BUQA 3DDFA 3E80A 1GHQA 3Q73B 1V7VA 5IL8A 1JCQB 3D5SA 1FT2B 4K3AA 1HMUA 1L7JA 4FNTA 4FNVA 3F59A 5ILHA 3VDBA 2CIQA 3SDRA 4DLQA 4BTYA 4GTQB 2OQEA 4BTWA 1V5CA 2P0VA 3QT3A 3EJPA 3OS7A 1RW9A 1IA6A 4D6JA 1N21A 5ILIA 4Q2BA 3WKFA 1W7CA 2ZXQA 2BRPA 2ZISB 3RX8A 1X1JA 2ZQ0A 3DSXB 3W7XA 1AGMA 5IK0A 4CE7A 2OW7A 3MWXA 3K25A 1RKYA 1LXMA 2F7QA 1G6IA 4D71A 1W6CA 3HXEB 2WYNA 4FXGB 2Z07A 1NS7A 1TQUA 3N9HA 3BUPA 4CJ1A 3BGAA 3WIRA 3WFAA 2WW0A 3DSWB 3PZ1B 4MU9A 2DRQA 3I3DA 1I8QA 1PX4A 1JCRB 2OOVC 3E33B 1R34A 3HIGA 5CD2A 1O5MB 4DUWA 2B39A 3SX1A 3E37B 2QNOA 2WY8A 3GLYA 2F6DA 4OK4A 5EAUA 1K1XA 1NSMA 3QFYA 2AHFA 1SIIA 2FUZA 4YCRA 3EJRA 1H39A 2E24A 3CZSA 4NEIA 3DRAB 2B4FA 3QSPA 4OJZA 3VD4A 1QWUA 1W6GA 3KSQB 2WW3A 4F10A 1MN0A 1O1TB 2CIRA 2F1AA 3X40A 1F4HA 1MMZA 1LD8B 4J5TA 2A73B 2EABA 2Y74A 1KSCA 3CU7A 1FCEA 4FJQA 3J7HA 1FP3A 1UT9A 2BRVX 2PMVA 1CEMA 3K7XA 3E73A 3KSLB 4YDEB 2H6IB 3Q79B 3QWTA 1DP0A 1JYXA 3I3BA 4YDOB 4KFFA 3MUY1 3KLSA 1EKMA 2E2VA 2I07B 2XHNA 2ONHA 4RNQA 1LTXB 2H6FB 4FNRA 4M76A 3BLCA 3DSTB 5ILKA 1NC5A 3HXCB 3T2OA 1WU4A 3A3VA 3P5PA 2FUTA 1KSDA 1N4QB 2HTAA 3RENA 4D6EA 3BVWA 2WIIB 5IKAA 1SO0A 3ECQA 3ANIA 1O6HA 3IMHA 1H36A 3H2WA 1TF4A 3DSVB 4BZEA 3BUDA 1FPPB 4D6GA 1PS3A 3WUXA 4D4CA 3H3KA 1LXKA 4KTRA 4KFDA 3KBUC 2DRSA 2G0DA 1O1SB 2ZL8A 1LF9A 3QFZA 3TF4A 3PMMA 2CQSA 4LNBB 1GA2A 1GAHA 3M73A 1H37A 1UMPA 1GSZA 3DPYB 3HXBB 2HTBA 2R2LB 2XWJB 1QAKA 3E1F1 3M78A 1KRFA 2E2TA 3ALAA 5DGRA 3Q1NA 2YFOA 1EGUA 4AYRA 1F9OA 3MUZ1 4TXTA 4LNVA 3G6JB 5JMDA 3EJSA 3LOYA 1N1ZA 1RQ5A 4GTOB 3QG0A 2XN2A 1O1RB 1TN8B 1LVNA 4FNUA 3X41A 4WVCA 4ZH5A 2CFKA 2OQEC 1JZ8A 4FNSA 5FO8B 1OJMA 4MMHA 1N4PB 2YX9A 1D6YA 3A0OA 2CFDA 3ANKA 3PGBA 1JZ7A 4DI5A 1KWFA 1A2VA 1QAFA 4Q88A 3MPHA 3T09A 3GT5A 4GTPB 1IVWA 3BVVA 1R76A 3E6UA 1RWCA 2ZZRA 4V1SA 1NSSA 1N20A 3T0AA 1JYVA 1TQWA 3VDCA 3DX4A 2WO0A 1V7XA 3QPFA 5AGDA 1NXCA 3Q7FB 3VSMA 5ILJA 1AV4A 3SQCA 1FBWA 3EUVB 3VD3A 1WMNA 3M02A 1QAZA 1FT1B 1GLMA 3X3YA 3D5RA 3BVUA 1H54A 1JOVA 1WMPA 4DODA 1YGAA 1N7QA 3HIIA 4BZHA 3BUBA 4GTRB 2CISA 3T33A 1OJNA 2XQWA 3QT9A 3NFVA 2VN7A 1MMXA 4TF4A 1DCEB 1JS4A 4GTMB 2EACA 1N7PA 1FBOA 2SQCA 2BB5A 1N7NA 1GXOA 1QALA 1JZ3A 1N1BA 5FOBB 2EADA 4AYQA 4FUSA 2XN0A 3VXDA 3AFLA 1DYUA 1R33A 5IM1A 3X3ZA 3PZ2B 3ACSA 4K35A 3D50A 2XWBB 2WOHA 4MBGB 4D6IA 1O6RA 4KFEA 3U7VA 1L1YA 1X81B 1HX9A 2F1BA
chains in the Genus database with same CATH topology
1TXKA 2WVXA 4J5TA 1Z45A 1C82A 2JKPA 3VD5A 1LOHA 4D6HA 1NSUA 3J7HA 3A24A 3DYPA 3IAPA 1RWFA 3NREA 2BRVX 1F4AA 3OB8A 2Q1FA 1NSRA 2D73A 1OJPA 4BZGA 1JYXA 1DP0A 3I3BA 1N7RA 3VD9A 2WW2A 3MUY1 3TY1A 3T0DA 2XHNA 4AQ0A 2X03A 3BLCA 1NSVA 1NKGA 1NS8A 3MV11 3T2OA 2FUQA 2BRWA 2WW1A 2WZSA 2FUTA 3DECA 2HTAA 3DCDA 1J0MA 1HN0A 1JYWA 5A1AA 1RWHA 4D6EA 3I3EA 3T2PA 1HMWA 1SO0A 3ECQA 4OK2A 3IMHA 3CZJA 1HN1A 4BZEA 3NJVA 1N7OA 4F13A 3DYOA 1K1WA 4D6GA 3E7JA 3NJXA 4OZWA 1K1YA 1MMUA 1LXKA 2WMJA 1F9GA 2WMHA 1LURA 4D72A 2WVXB 1F1SA 4RNLA 4D6CA 3SEPA 2WMIA 1LF9A 1YQ2A 1JZ4A 1JZ6A 1NSZA 1RWGA 1NS2A 3E80A 2HTBA 3VD7A 3E1F1 1HMUA 1L7JA 1SNZA 3Q1NA 1EGUA 1X1HA 4FNVA 2JKAA 3VDBA 2CIQA 3NNBA 3MUZ1 2WCOA 5JMDA 1LF6A 1PX3A 1ULVA 3IAQA 3WVFA 1JZ2A 4BZFA 3OS7A 4DUVA 1RW9A 1JZ8A 1OJMA 4MMHA 4D6JA 2ZXQA 1JZ7A 3A0OA 1MMYA 2BRPA 5E1QA 1X1JA 2ZQ0A 3T09A 1X1IA 1RWCA 1NSSA 3MWXA 3K25A 3T0AA 1JYVA 3VDCA 3VSMA 1LXMA 2WMGA 4D71A 1NS4A 3DYMA 1NS7A 2WMIB 1CB8A 2WVYA 3VD3A 3BS6A 1QAZA 3MV01 1L7KA 3BGAA 5JMFA 1JOVA 4D6FA 1NSXA 3VDAA 3WFAA 2WMFA 2WW0A 1YGAA 4DUXA 4TTGA 1N7QA 1W3YA 4BZHA 1OJOA 1NS0A 3I3DA 1I8QA 1HM3A 1PX4A 2CISA 1OJNA 2WDAA 3NFVA 2WMKA 1MMXA 4DUWA 1HV6A 3T2QA 1N7PA 2XSGA 4OK4A 1N7NA 4OZVA 1K1XA 1J0NA 1NSMA 1JZ3A 1RWAA 2JKEA 3AFLA 2WVZA 2E24A 4NEIA 4D6DA 3VSNA 1JYNA 4E1YA 4OJZA 1HM2A 3VD4A 1UG9A 4D6IA 3OBAA 3T08A 3T0BA 2WW3A 4F10A 1MN0A 2CIRA 1JZ5A 1F4HA 2E22A 1MMZA 4MMIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TXK A;  2WVX A;  1Z45 A;  1C82 A;  2JKP A;  3VD5 A;  1LOH A;  4D6H A;  1NSU A;  3J7H A;  3A24 A;  3DYP A;  3IAP A;  1RWF A;  3NRE A;  2BRV X;  1F4A A;  3OB8 A;  2Q1F A;  1NSR A;  2D73 A;  1OJP A;  4BZG A;  1JYX A;  1DP0 A;  3I3B A;  1N7R A;  3VD9 A;  2WW2 A;  3MUY 1;  3T0D A;  2XHN A;  4AQ0 A;  2X03 A;  1NSV A;  1NKG A;  1NS8 A;  3MV1 1;  3T2O A;  2FUQ A;  2BRW A;  2WW1 A;  2WZS A;  2FUT A;  3DEC A;  2HTA A;  3DCD A;  1J0M A;  1HN0 A;  1JYW A;  5A1A A;  1RWH A;  4D6E A;  3I3E A;  3T2P A;  1HMW A;  1SO0 A;  3ECQ A;  4OK2 A;  3IMH A;  3CZJ A;  1HN1 A;  4BZE A;  3NJV A;  1N7O A;  4F13 A;  3DYO A;  1K1W A;  4D6G A;  3E7J A;  3NJX A;  4OZW A;  1K1Y A;  1MMU A;  1LXK A;  2WMJ A;  1F9G A;  2WMH A;  1LUR A;  4D72 A;  2WVX B;  1F1S A;  4RNL A;  4D6C A;  3SEP A;  2WMI A;  1LF9 A;  1YQ2 A;  1JZ4 A;  1JZ6 A;  1NSZ A;  1RWG A;  1NS2 A;  3E80 A;  2HTB A;  3VD7 A;  3E1F 1;  1HMU A;  1L7J A;  1SNZ A;  3Q1N A;  1EGU A;  1X1H A;  4FNV A;  2JKA A;  3VDB A;  2CIQ A;  3NNB A;  3MUZ 1;  2WCO A;  5JMD A;  1LF6 A;  1PX3 A;  1ULV A;  3IAQ A;  1JZ2 A;  4BZF A;  3OS7 A;  4DUV A;  1RW9 A;  1JZ8 A;  1OJM A;  4MMH A;  4D6J A;  2ZXQ A;  1JZ7 A;  3A0O A;  1MMY A;  2BRP A;  5E1Q A;  1X1J A;  2ZQ0 A;  3T09 A;  1X1I A;  1RWC A;  1NSS A;  3MWX A;  3K25 A;  3T0A A;  1JYV A;  3VDC A;  3VSM A;  1LXM A;  2WMG A;  4D71 A;  1NS4 A;  3DYM A;  1NS7 A;  2WMI B;  1CB8 A;  2WVY A;  3VD3 A;  1QAZ A;  3MV0 1;  1L7K A;  3BGA A;  5JMF A;  1JOV A;  4D6F A;  1NSX A;  3VDA A;  3WFA A;  2WMF A;  2WW0 A;  1YGA A;  4DUX A;  4TTG A;  1N7Q A;  1W3Y A;  4BZH A;  1OJO A;  1NS0 A;  3I3D A;  1I8Q A;  1HM3 A;  1PX4 A;  2CIS A;  1OJN A;  2WDA A;  3NFV A;  2WMK A;  1MMX A;  4DUW A;  1HV6 A;  3T2Q A;  1N7P A;  2XSG A;  4OK4 A;  1N7N A;  4OZV A;  1K1X A;  1J0N A;  1NSM A;  1JZ3 A;  1RWA A;  2JKE A;  3AFL A;  2WVZ A;  2E24 A;  4NEI A;  4D6D A;  3VSN A;  1JYN A;  4E1Y A;  4OJZ A;  1HM2 A;  3VD4 A;  1UG9 A;  4D6I A;  3OBA A;  3T08 A;  3T0B A;  2WW3 A;  4F10 A;  1MN0 A;  2CIR A;  1JZ5 A;  1F4H A;  2E22 A;  1MMZ A;  4MMI A; 
#chains in the Genus database with same CATH topology
 1TXK A;  2WVX A;  1H13 A;  5E2J A;  3WC3 A;  1W6J A;  3NRE A;  5EAT A;  3S4B A;  3DYP A;  1RWF A;  1NI1 B;  4D1J A;  2D5J A;  2BT3 A;  2F7P A;  3M7C A;  3OB8 A;  3RX7 A;  2KXS A;  1OJP A;  1F9D A;  3PZ4 B;  4D94 A;  3KN4 A;  5KBP A;  1N7R A;  1UI7 A;  3QDE A;  3WIQ A;  3TY1 A;  5MEH A;  3W5N A;  2OW6 A;  5EAS A;  3DDG A;  3SDU A;  2F7R A;  3OED A;  1TN6 B;  4LNG B;  1NKG A;  2YFN A;  3QR8 A;  2FUQ A;  3M7L A;  2WZS A;  4GTV B;  1TQV A;  4WVB A;  3KBT C;  1HTY A;  2AHG A;  4EV5 A;  5A1A A;  1RWH A;  2DRO A;  3W7T A;  4DLO A;  3ON6 A;  3Q7A B;  3WIW A;  3W7U A;  3CZJ A;  4F13 A;  3M7B A;  1GXM A;  3DYO A;  1K1W A;  1LD7 B;  1V5D A;  2D8L A;  3E7J A;  4L6X A;  4OZW A;  3M72 A;  1K1Y A;  3NJX A;  1H3A A;  2WVX B;  3QRY A;  1F1S A;  3S9V A;  2C11 A;  2JJB A;  2WMI A;  2CFW A;  1TQT A;  1JZ4 A;  1CLC A;  1NSZ A;  1JZ6 A;  2E2U A;  2FV1 A;  1RWG A;  2CFL A;  1XWQ A;  3SDQ A;  2YIK A;  3D51 A;  3DX2 A;  3M71 A;  5M7Y A;  1D8E B;  5CZL A;  3SAE A;  5IK9 A;  2JG0 A;  4ZG8 A;  5KKB A;  2FYV A;  3MI6 A;  3QXF A;  5C05 A;  3Q78 B;  3KII A;  3SXX A;  3NNB A;  2WCO A;  4KTP A;  1WZZ A;  3EQA A;  3BLB A;  1SA4 B;  1PX3 A;  2ALW A;  1D6U A;  1TN7 B;  4Z4L A;  4AYP A;  3IAQ A;  4D1I A;  3WVF A;  1JZ2 A;  3S4D A;  3RX5 A;  4DUV A;  2FV0 A;  4FXK B;  4KKI A;  1N4S B;  1C3D A;  2AFA A;  3VW5 A;  1H3C A;  4C1S A;  1KZP B;  1N23 A;  3C72 B;  1K72 A;  1KFG A;  1N9E A;  2V3N A;  1H35 A;  5ILZ A;  3EU5 B;  1US1 A;  3BUI A;  2NVP A;  4BOK A;  3E32 B;  2WMI B;  3RSY A;  2WOF A;  3MV0 1;  1S63 B;  3K11 A;  3DX3 A;  5JMF A;  4EV2 A;  3P5R A;  1TNB B;  3OXU A;  2WMF A;  1SA5 B;  1OJO A;  1HXK A;  3M74 A;  3EJU A;  1HM3 A;  1O79 A;  1H3B A;  4EL8 A;  3NBJ A;  1QSJ A;  3ACT A;  1HXG A;  2W0Q A;  1KS8 A;  4D4D A;  4WU0 A;  3M00 A;  3PYA A;  2IEJ B;  1UI8 A;  2WYH A;  1D8D B;  3W7S A;  1QBQ B;  3EJQ A;  4OZV A;  2CQT A;  3X42 A;  1RWA A;  5IKH A;  2D1W A;  2CWV A;  4D4B A;  2WIN B;  5GW7 A;  4BOJ A;  3RRS A;  3CZN A;  4D6D A;  3WA2 X;  3RJ3 A;  1JYN A;  5IL3 A;  5ILY A;  2F7O A;  1HM2 A;  3UD1 A;  2XFG A;  4ZRP A;  2FBA A;  1FAE A;  3AMO A;  1JZ5 A;  1KKT A;  2JF4 A;  5M7I A;  1IVU A;  2E22 A;  1SIH A;  3AFJ A;  2Y73 A;  3WKI A;  2CG0 A;  3S4C A;  3VD5 A;  1LOH A;  1H14 A;  1NSU A;  3A24 A;  3IAP A;  2C10 A;  2CG1 A;  4BTX A;  2Q1F A;  4V1R A;  1NSR A;  2D73 A;  3PYB A;  2PN5 A;  4BZG A;  3NBB A;  3D52 A;  4D4A A;  2F18 A;  3VD9 A;  3T0D A;  2A8Z A;  1H12 A;  3CV5 A;  1N95 B;  1N4R B;  3DSU B;  4LIX A;  1QX1 A;  2GZ6 A;  2V8K A;  1HZF A;  1W6K A;  1NSV A;  1NS8 A;  3DX1 A;  3MV1 1;  3Q75 B;  3SFX B;  1IVV A;  3DEC A;  4GL3 A;  3DCD A;  1HWW A;  1J0M A;  1IS9 A;  4AYO A;  3D4Y A;  3T2P A;  1HMW A;  5CA3 A;  4OK2 A;  3EJT A;  1HN1 A;  4JJJ A;  3HI7 A;  1N7O A;  3S4A A;  5JPM B;  4XUV A;  2H6G B;  1IA7 A;  3AMO B;  4L9P B;  1F9G A;  3HXF B;  4GAX A;  1IQX A;  5IK6 A;  1DL2 A;  1N22 A;  1MZC B;  2J5C A;  2NOJ A;  4FNP A;  4RNL A;  4D6C A;  1SPU A;  1W2Z A;  1HXC A;  1YQ2 A;  4WVA A;  1IVX A;  1PU4 A;  2CFG A;  3P2C A;  1FO2 A;  1NS2 A;  2V3P A;  3H7L A;  4Z4J A;  1HXA A;  3VD7 A;  2F0Y B;  2EAE A;  2KXR A;  1RJO A;  1SNZ A;  2CWU A;  3G4D A;  3M01 A;  3SFY B;  3PQI A;  3K5T A;  1O6Q A;  1N24 A;  1X1H A;  2JKA A;  3BVT A;  3ANJ A;  5ILD A;  4ZRQ A;  1LF6 A;  3LZ9 A;  1ULV A;  1XWT A;  3HXD B;  4FNQ A;  2BB6 A;  5GY3 A;  3E34 B;  4BZF A;  3DX0 A;  1TNY B;  1TNU B;  3WKG A;  4DOE A;  1MMY A;  5E1Q A;  3EZ8 A;  2WY7 A;  1X1I A;  4L0G A;  3EU8 A;  3D4Z A;  2V8I A;  2WMG A;  3M75 A;  2GH4 A;  1NS4 A;  3DYM A;  3KQ4 A;  4EHM B;  1CB8 A;  2WVY A;  3BS6 A;  4CJ0 A;  1L7K A;  1KZO B;  1NSX A;  4D6F A;  1G9G A;  3VDA A;  4DUX A;  4UFC A;  4TTG A;  2OKX A;  1W3Y A;  1NS0 A;  2OOV A;  5GZK A;  1WU6 A;  1AVL A;  1X9D A;  1S64 B;  1TNZ B;  2WDA A;  2WMK A;  4D8O A;  3E30 B;  1HV6 A;  3CIH A;  3T2Q A;  5DGQ A;  2GOX A;  2XSG A;  3WA3 A;  3UD2 A;  1J0N A;  1GXN A;  4GTT B;  2JKE A;  2DRR A;  3N0F A;  3G4F A;  4KKJ A;  2WVZ A;  3X17 A;  1AVK A;  1JRQ A;  2ZBL A;  3VSN A;  1AYX A;  3DSS B;  4E1Y A;  2G02 A;  2RDY A;  1TU5 A;  2ONG A;  3M7E A;  1UG9 A;  2ZIR B;  3OBA A;  3T08 A;  3SDV A;  2CWT A;  3W7W A;  3T0B A;  2WGQ A;  3D3I A;  1D6Z A;  2VN4 A;  1N94 B;  3N0G A;  1KSI A;  1QWN A;  5FO9 B;  4MMI A;  1TNO B;  1DOG A;  1Z45 A;  1C82 A;  3WKH A;  2JKP A;  1G9J A;  3PZ3 B;  2WYI A;  5FO7 B;  4D6H A;  2V8J A;  1WMO A;  3SDT A;  3T0U A;  1F4A A;  3GZK A;  1XW2 A;  1IQY A;  1W4N A;  2WW2 A;  3BVX A;  1QQF A;  1HCU A;  1V7W A;  5JPN B;  4AQ0 A;  4ONT A;  1NL4 B;  2X03 A;  3W5M A;  3M76 A;  5DHI A;  1SQC A;  2BRW A;  1OAC A;  2PNC A;  2WW1 A;  1GAI A;  4ZH1 A;  1HN0 A;  1JYW A;  3M77 A;  1O7D D;  3I3E A;  4QT9 A;  3LVT A;  1JCS B;  2XN1 A;  1TQS A;  1G87 A;  1N9A B;  3NJV A;  2RI8 A;  1KRE A;  1FO3 A;  2BBC A;  1VD5 A;  4GTS B;  1MMU A;  1W5Z A;  2WMJ A;  2WMH A;  2RGK A;  1LUR A;  3X3X A;  4D72 A;  2RI9 A;  1IU7 A;  2H6H B;  5DHK A;  3QXQ A;  1WU5 A;  1FMI A;  1L2A A;  3SEP A;  2BED B;  3BUQ A;  3DDF A;  3E80 A;  1GHQ A;  3Q73 B;  1V7V A;  5IL8 A;  1JCQ B;  3D5S A;  1FT2 B;  4K3A A;  1HMU A;  1L7J A;  4FNT A;  4FNV A;  3F59 A;  5ILH A;  3VDB A;  2CIQ A;  3SDR A;  4DLQ A;  4BTY A;  4GTQ B;  2OQE A;  4BTW A;  1V5C A;  2P0V A;  3QT3 A;  3EJP A;  3OS7 A;  1RW9 A;  1IA6 A;  4D6J A;  1N21 A;  5ILI A;  4Q2B A;  3WKF A;  1W7C A;  2ZXQ A;  2BRP A;  2ZIS B;  3RX8 A;  1X1J A;  2ZQ0 A;  3DSX B;  3W7X A;  1AGM A;  5IK0 A;  4CE7 A;  2OW7 A;  3MWX A;  3K25 A;  1RKY A;  1LXM A;  2F7Q A;  1G6I A;  4D71 A;  1W6C A;  3HXE B;  2WYN A;  4FXG B;  2Z07 A;  1NS7 A;  1TQU A;  3N9H A;  3BUP A;  4CJ1 A;  3BGA A;  3WIR A;  3WFA A;  2WW0 A;  3DSW B;  3PZ1 B;  4MU9 A;  2DRQ A;  3I3D A;  1I8Q A;  1PX4 A;  1JCR B;  2OOV C;  3E33 B;  1R34 A;  3HIG A;  5CD2 A;  1O5M B;  4DUW A;  2B39 A;  3SX1 A;  3E37 B;  2QNO A;  2WY8 A;  3GLY A;  2F6D A;  4OK4 A;  5EAU A;  1K1X A;  1NSM A;  3QFY A;  2AHF A;  1SII A;  2FUZ A;  4YCR A;  3EJR A;  1H39 A;  2E24 A;  3CZS A;  4NEI A;  3DRA B;  2B4F A;  3QSP A;  4OJZ A;  3VD4 A;  1QWU A;  1W6G A;  3KSQ B;  2WW3 A;  4F10 A;  1MN0 A;  1O1T B;  2CIR A;  2F1A A;  3X40 A;  1F4H A;  1MMZ A;  1LD8 B;  4J5T A;  2A73 B;  2EAB A;  2Y74 A;  1KSC A;  3CU7 A;  1FCE A;  4FJQ A;  3J7H A;  1FP3 A;  1UT9 A;  2BRV X;  2PMV A;  1CEM A;  3K7X A;  3E73 A;  3KSL B;  4YDE B;  2H6I B;  3Q79 B;  3QWT A;  1DP0 A;  1JYX A;  3I3B A;  4YDO B;  4KFF A;  3MUY 1;  3KLS A;  1EKM A;  2E2V A;  2I07 B;  2XHN A;  2ONH A;  4RNQ A;  1LTX B;  2H6F B;  4FNR A;  4M76 A;  3BLC A;  3DST B;  5ILK A;  1NC5 A;  3HXC B;  3T2O A;  1WU4 A;  3A3V A;  3P5P A;  2FUT A;  1KSD A;  1N4Q B;  2HTA A;  3REN A;  4D6E A;  3BVW A;  2WII B;  5IKA A;  1SO0 A;  3ECQ A;  3ANI A;  1O6H A;  3IMH A;  1H36 A;  3H2W A;  1TF4 A;  3DSV B;  4BZE A;  3BUD A;  1FPP B;  4D6G A;  1PS3 A;  3WUX A;  4D4C A;  3H3K A;  1LXK A;  4KTR A;  4KFD A;  3KBU C;  2DRS A;  2G0D A;  1O1S B;  2ZL8 A;  1LF9 A;  3QFZ A;  3TF4 A;  3PMM A;  2CQS A;  4LNB B;  1GA2 A;  1GAH A;  3M73 A;  1H37 A;  1UMP A;  1GSZ A;  3DPY B;  3HXB B;  2HTB A;  2R2L B;  2XWJ B;  1QAK A;  3E1F 1;  3M78 A;  1KRF A;  2E2T A;  3ALA A;  5DGR A;  3Q1N A;  2YFO A;  1EGU A;  4AYR A;  1F9O A;  3MUZ 1;  4TXT A;  4LNV A;  3G6J B;  5JMD A;  3EJS A;  3LOY A;  1N1Z A;  1RQ5 A;  4GTO B;  3QG0 A;  2XN2 A;  1O1R B;  1TN8 B;  1LVN A;  4FNU A;  3X41 A;  4WVC A;  4ZH5 A;  2CFK A;  2OQE C;  1JZ8 A;  4FNS A;  5FO8 B;  1OJM A;  4MMH A;  1N4P B;  2YX9 A;  1D6Y A;  3A0O A;  2CFD A;  3ANK A;  3PGB A;  1JZ7 A;  4DI5 A;  1KWF A;  1A2V A;  1QAF A;  4Q88 A;  3MPH A;  3T09 A;  3GT5 A;  4GTP B;  1IVW A;  3BVV A;  1R76 A;  3E6U A;  1RWC A;  2ZZR A;  4V1S A;  1NSS A;  1N20 A;  3T0A A;  1JYV A;  1TQW A;  3VDC A;  3DX4 A;  2WO0 A;  1V7X A;  3QPF A;  5AGD A;  1NXC A;  3Q7F B;  3VSM A;  5ILJ A;  1AV4 A;  3SQC A;  1FBW A;  3EUV B;  3VD3 A;  1WMN A;  3M02 A;  1QAZ A;  1FT1 B;  1GLM A;  3X3Y A;  3D5R A;  3BVU A;  1H54 A;  1JOV A;  1WMP A;  4DOD A;  1YGA A;  1N7Q A;  3HII A;  4BZH A;  3BUB A;  4GTR B;  2CIS A;  3T33 A;  1OJN A;  2XQW A;  3QT9 A;  3NFV A;  2VN7 A;  1MMX A;  4TF4 A;  1DCE B;  1JS4 A;  4GTM B;  2EAC A;  1N7P A;  1FBO A;  2SQC A;  2BB5 A;  1N7N A;  1GXO A;  1QAL A;  1JZ3 A;  1N1B A;  5FOB B;  2EAD A;  4AYQ A;  4FUS A;  2XN0 A;  3VXD A;  3AFL A;  1DYU A;  1R33 A;  5IM1 A;  3X3Z A;  3PZ2 B;  3ACS A;  4K35 A;  3D50 A;  2XWB B;  2WOH A;  4MBG B;  4D6I A;  1O6R A;  4KFE A;  3U7V A;  1L1Y A;  1X81 B;  1HX9 A;  2F1B A; 
#chains in the Genus database with same CATH homology
 1TXK A;  2WVX A;  4J5T A;  1Z45 A;  1C82 A;  2JKP A;  3VD5 A;  1LOH A;  4D6H A;  1NSU A;  3J7H A;  3A24 A;  3DYP A;  3IAP A;  1RWF A;  3NRE A;  2BRV X;  1F4A A;  3OB8 A;  2Q1F A;  1NSR A;  2D73 A;  1OJP A;  4BZG A;  1JYX A;  1DP0 A;  3I3B A;  1N7R A;  3VD9 A;  2WW2 A;  3MUY 1;  3TY1 A;  3T0D A;  2XHN A;  4AQ0 A;  2X03 A;  3BLC A;  1NSV A;  1NKG A;  1NS8 A;  3MV1 1;  3T2O A;  2FUQ A;  2BRW A;  2WW1 A;  2WZS A;  2FUT A;  3DEC A;  2HTA A;  3DCD A;  1J0M A;  1HN0 A;  1JYW A;  5A1A A;  1RWH A;  4D6E A;  3I3E A;  3T2P A;  1HMW A;  1SO0 A;  3ECQ A;  4OK2 A;  3IMH A;  3CZJ A;  1HN1 A;  4BZE A;  3NJV A;  1N7O A;  4F13 A;  3DYO A;  1K1W A;  4D6G A;  3E7J A;  3NJX A;  4OZW A;  1K1Y A;  1MMU A;  1LXK A;  2WMJ A;  1F9G A;  2WMH A;  1LUR A;  4D72 A;  2WVX B;  1F1S A;  4RNL A;  4D6C A;  3SEP A;  2WMI A;  1LF9 A;  1YQ2 A;  1JZ4 A;  1JZ6 A;  1NSZ A;  1RWG A;  1NS2 A;  3E80 A;  2HTB A;  3VD7 A;  3E1F 1;  1HMU A;  1L7J A;  1SNZ A;  3Q1N A;  1EGU A;  1X1H A;  4FNV A;  2JKA A;  3VDB A;  2CIQ A;  3NNB A;  3MUZ 1;  2WCO A;  5JMD A;  1LF6 A;  1PX3 A;  1ULV A;  3IAQ A;  3WVF A;  1JZ2 A;  4BZF A;  3OS7 A;  4DUV A;  1RW9 A;  1JZ8 A;  1OJM A;  4MMH A;  4D6J A;  2ZXQ A;  1JZ7 A;  3A0O A;  1MMY A;  2BRP A;  5E1Q A;  1X1J A;  2ZQ0 A;  3T09 A;  1X1I A;  1RWC A;  1NSS A;  3MWX A;  3K25 A;  3T0A A;  1JYV A;  3VDC A;  3VSM A;  1LXM A;  2WMG A;  4D71 A;  1NS4 A;  3DYM A;  1NS7 A;  2WMI B;  1CB8 A;  2WVY A;  3VD3 A;  3BS6 A;  1QAZ A;  3MV0 1;  1L7K A;  3BGA A;  5JMF A;  1JOV A;  4D6F A;  1NSX A;  3VDA A;  3WFA A;  2WMF A;  2WW0 A;  1YGA A;  4DUX A;  4TTG A;  1N7Q A;  1W3Y A;  4BZH A;  1OJO A;  1NS0 A;  3I3D A;  1I8Q A;  1HM3 A;  1PX4 A;  2CIS A;  1OJN A;  2WDA A;  3NFV A;  2WMK A;  1MMX A;  4DUW A;  1HV6 A;  3T2Q A;  1N7P A;  2XSG A;  4OK4 A;  1N7N A;  4OZV A;  1K1X A;  1J0N A;  1NSM A;  1JZ3 A;  1RWA A;  2JKE A;  3AFL A;  2WVZ A;  2E24 A;  4NEI A;  4D6D A;  3VSN A;  1JYN A;  4E1Y A;  4OJZ A;  1HM2 A;  3VD4 A;  1UG9 A;  4D6I A;  3OBA A;  3T08 A;  3T0B A;  2WW3 A;  4F10 A;  1MN0 A;  2CIR A;  1JZ5 A;  1F4H A;  2E22 A;  1MMZ A;  4MMI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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