1N7PA

Streptococcus pneumoniae hyaluronate lyase w292a/f343v double mutant
Total Genus 258
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWADYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPVKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords HYALURONIDASE
publication title The function of hydrophobic residues in the catalytic cleft of Streptococcus pneumoniae hyaluronate lyase. Kinetic characterization of mutant enzyme forms
pubmed doi rcsb
source organism Streptococcus pneumoniae
total genus 258
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1n7pA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1n7pA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1n7pA01
2HTAA 1RW9A 3VDBA 4BZEA 3VD3A 3J7HA 5A1AA 2WMFA 3VD7A 1JOVA 2WMIB 3K25A 1OJMA 1N7QA 1MMUA 4D6HA 3NJVA 2WVXA 3CZJA 3T09A 4D71A 3BGAA 1F4HA 2WW3A 1SNZA 1HM2A 4NEIA 1MMYA 2WMKA 1W3YA 1NSUA 1NSVA 2JKEA 3I3DA 1F1SA 1LF9A 2D73A 4AQ0A 2BRWA 3DYMA 1L7JA 1MN0A 2XHNA 1X1IA 1K1XA 1N7OA 1LXMA 1F4AA 1JZ6A 3VD5A 4BZGA 3VSMA 4OK4A 2ZXQA 2WW1A 4D6GA 3T0BA 3T0AA 2JKPA 3T2OA 1JZ8A 2WMIA 1RWHA 3E80A 1J0MA 1N7PA 4OZWA 3DYPA 4BZFA 2CISA 2ZQ0A 1JYWA 3OBAA 4BZHA 2X03A 1PX3A 3MV01 3ECQA 3NFVA 4D6FA 1NSZA 3VDCA 2WZSA 3I3EA 2BRVX 3E7JA 2CIRA 4D6IA 3T2QA 4D6CA 2WCOA 1NSMA 1NS0A 1QAZA 2WMJA 1RWCA 3NJXA 1EGUA 4DUWA 3IAPA 1OJOA 2FUTA 1LXKA 1X1HA 3IAQA 2WMHA 1K1YA 1JZ7A 3DCDA 1JZ5A 5E1QA 1OJPA 1MMXA 2WVZA 3VDAA 1NS2A 1JYVA 1HMUA 1HV6A 3SEPA 1LOHA 5JMFA 3MUZ1 3T08A 1JZ2A 1LF6A 4D6EA 1LURA 3A24A 3AFLA 3MUY1 3NNBA 4E1YA 1J0NA 1HN1A 1NKGA 3E1F1 1L7KA 4OJZA 2JKAA 1RWFA 4F13A 2E22A 2WVYA 4OZVA 1HN0A 2CIQA 4RNLA 1NS4A 4MMHA 3MV11 1MMZA 2HTBA 1JYNA 3MWXA 1K1WA 3OS7A 2WDAA 3Q1NA 1YGAA 1NSXA 1N7RA 1JYXA 1HMWA 3VD4A 1NSSA 2XSGA 4D6DA 3A0OA 1OJNA 1C82A 5JMDA 3T0DA 1YQ2A 3DYOA 1ULVA 2WW2A 1JZ3A 1UG9A 1CB8A 3DECA 4F10A 1NS8A 3T2PA 2WVXB 4MMIA 4DUXA 1N7NA 4D6JA 3VD9A 4FNVA 1F9GA 2E24A 2FUQA 4D72A 1Z45A 1DP0A 3I3BA 4OK2A 3IMHA 1SO0A 4TTGA 2WW0A 3VSNA 1RWGA 2WMGA 1TXKA 3NREA 3OB8A 2BRPA 4DUVA 1JZ4A 1HM3A 2Q1FA 1PX4A 1RWAA 3WFAA 1I8QA 1NSRA 1NS7A 1X1JA
chains in the Genus database with same CATH superfamily
2HTAA 3HIGA 3WKGA 1WMPA 4BZEA 5IKAA 3J7HA 2WMIB 3K25A 1KWFA 3AMOA 1HCUA 1N1BA 4ZG8A 1N4RB 3M01A 1WU4A 3WUXA 5AGDA 1O1SB 2NOJA 5M7YA 1WU6A 4V1RA 4D71A 3BGAA 3T09A 4ZRPA 2EACA 4WVCA 1RJOA 4FUSA 4DLOA 2CFKA 3M75A 1D8EB 3UD2A 2OOVA 1TNBB 3WA2X 3HXDB 2D73A 1X81B 2BRWA 4AYOA 4DODA 4JJJA 2GZ6A 2ZISB 1MN0A 3DYMA 1O79A 1TNZB 2D5JA 2DROA 4D4AA 3QT9A 2XFGA 5IK6A 1H14A 1F4AA 2V3NA 3KSLB 3N0GA 3X41A 4D6GA 1FBOA 5ILJA 2RI9A 4FNTA 1W6GA 2DRSA 3EU5B 4DI5A 3HIIA 1J0MA 3BUDA 4BZFA 4BZHA 5KKBA 3ECQA 4D6FA 3VDCA 3I3EA 2C10A 2BRVX 1H39A 3E7JA 1XW2A 3MI6A 4D6CA 2WCOA 3BS6A 4Z4LA 3LZ9A 1D6ZA 2Y74A 1WU5A 2JJBA 3PMMA 1JCQB 1KKTA 4YDEB 4ZH5A 5E2JA 1O6RA 3NJXA 3QDEA 3IAPA 2BB6A 4BTWA 5GY3A 1O1RB 3IAQA 3RJ3A 2CQTA 3P5RA 3BVXA 4FNSA 1V5CA 3DCDA 3P5PA 4CE7A 1OJPA 1MMXA 3E73A 2NVPA 1IU7A 1LVNA 2AHGA 1NS2A 1KS8A 4WVAA 1N20A 1H3BA 5JMFA 1SIHA 1H3AA 3QR8A 3DX2A 4FNPA 3SEPA 3T08A 3G6JB 1WZZA 2F0YB 3WIWA 4GTVB 1SA4B 3ACTA 3X40A 1GSZA 4E1YA 2OW6A 1AV4A 4D4BA 3E1F1 1L7KA 1JCSB 4F13A 3RRSA 2F6DA 2WVYA 4EHMB 4K3AA 1TQTA 2CIQA 4RNLA 3N0FA 2WOFA 1JYNA 3MWXA 2VN4A 4MU9A 4LIXA 2PN5A 1FT2B 2KXRA 3QXQA 1V7WA 4D4CA 1IA7A 1HMWA 3WIRA 1NSSA 3M76A 4D6DA 1WMNA 1C82A 3P2CA 1H36A 3T0DA 1TN8B 4L0GA 3GZKA 3N9HA 3PYAA 3W7UA 3DYOA 5M7IA 3D5RA 1UG9A 2DRQA 3DDGA 1CB8A 1NS8A 3S4AA 3CIHA 1KSIA 2CQSA 4GTTB 3WA3A 1N7NA 3VD9A 1DP0A 3W7XA 3BUBA 4OK2A 4TTGA 4DUVA 3SFXB 1IQXA 1GAIA 2CFGA 3PGBA 3BUIA 1I8QA 2VN7A 3DSSB 3CV5A 3RX8A 1HXCA 3T0AA 2XN0A 1US1A 3VD3A 3X3YA 3W5NA 2WMFA 1JOVA 1D6YA 1FBWA 2J5CA 1W2ZA 1H35A 3HXFB 2RDYA 4KKIA 2WVXA 4RNQA 2ZZRA 4K35A 1L2AA 1F4HA 2WW3A 3K11A 1TQUA 1HM2A 4NEIA 1N24A 2SQCA 2WMKA 5JPNB 1N22A 5IKHA 1TQSA 1FCEA 2XN1A 1HXKA 2FUZA 3M74A 5ILKA 2H6HB 5ILDA 2XQWA 4KFDA 1N21A 1IVVA 4DLQA 3EJQA 5CZLA 3SDQA 3W7SA 2R2LB 3ALAA 4FNUA 2DRRA 3SFYB 2WINB 2GOXA 1H54A 4OK4A 3VSMA 2WW1A 2ZXQA 3T0BA 3T2OA 1JZ8A 1DL2A 3BVUA 3E80A 5KBPA 2WGQA 1W6KA 3DYPA 2ZQ0A 3DX0A 1W7CA 2X03A 1PX3A 4KKJA 1G6IA 3T2QA 2WY8A 4YDOB 4GAXA 2IEJB 4ONTA 1UI8A 4XUVA 3X3XA 3U7VA 1KRFA 4DUWA 4FXGB 1KSDA 1N1ZA 3H2WA 3SDRA 1N95B 3K5TA 3K7XA 3S4BA 3Q75B 1JZ5A 3WKHA 1KFGA 4KTRA 3RX7A 3EJPA 1O5MB 3Q78B 5FO7B 3DX1A 3EJSA 5CA3A 1HX9A 4WU0A 3D52A 4BTYA 5FOBB 1S63B 2H6GB 2XWJB 1LF6A 2OQEC 3RENA 2CWTA 3D51A 3AFLA 3MUY1 1TF4A 2F7OA 3OXUA 2CFWA 4ZH1A 3BUQA 1J0NA 2WOHA 2PMVA 2FYVA 3RX5A 2BBCA 4KTPA 3C72B 2CG0A 4UFCA 3DSWB 1H12A 5JPMB 1N9AB 2ZBLA 3WC3A 2PNCA 1FPPB 3MV11 3KSQB 3LOYA 1K1WA 3OS7A 3WIQA 1V7VA 1N7RA 1JCRB 2Z07A 4GTQB 1S64B 4DOEA 2FV0A 3ANJA 3SDVA 3BLBA 1GHQA 1TQWA 1PU4A 3QPFA 2KXSA 2BT3A 5CD2A 1G9JA 3BUPA 2D1WA 1YQ2A 3D4ZA 3CZSA 1ULVA 2E2VA 3AMOB 4FNQA 4AYPA 3DECA 4F10A 1TNUB 1MZCB 4D1JA 2G02A 2H6FB 3W7TA 3M7LA 1F9GA 1VD5A 2E24A 4FNVA 5DGQA 2YX9A 3DDFA 2EABA 3MPHA 3IMHA 4BOKA 1SO0A 2WMGA 1RWGA 1SQCA 4BTXA 3NREA 5IK0A 2WYNA 1W6JA 1X9DA 1SA5B 3KBTC 2Q1FA 1FMIA 1GLMA 1PX4A 3CZNA 3SX1A 3PZ3B 1FP3A 1TN6B 3VW5A 1NSRA 3BVWA 4QT9A 3KQ4A 1X1JA 4EV2A 3CU7A 3DSUB 3D50A 1KZOB 3DSVB 2EAEA 1O1TB 4CJ1A 2BB5A 3E6UA 3G4FA 1OJMA 1N7QA 4AYRA 2WY7A 1AYXA 3PQIA 3DRAB 3CZJA 3RSYA 1SNZA 1R76A 3HXBB 1AVLA 1QWNA 1CEMA 1UMPA 1NSVA 2ALWA 3I3DA 4EL8A 1DYUA 1L7JA 1SIIA 2BEDB 4GTOB 4Z4JA 1GA2A 1O6HA 1O6QA 1LXMA 1JZ6A 1GAHA 2FV1A 5GW7A 3VD5A 3X17A 2F7PA 1C3DA 1DCEB 3LVTA 2RI8A 2WMIA 5DGRA 1N7PA 3QSPA 3QFZA 4OZWA 4YCRA 2OKXA 3PZ4B 1R34A 1JYWA 3AFJA 4MBGB 4GTMB 3EJUA 3MV01 3QWTA 3T33A 3X42A 2CIRA 1GXNA 2G0DA 3QXFA 2YIKA 1R33A 2YFNA 1RWCA 2F7RA 2OQEA 3KLSA 1GXOA 1QSJA 1QQFA 3G4DA 3DX4A 2WMHA 4LNVA 3KN4A 1K1YA 2GH4A 2XWBB 3VXDA 5E1QA 1V7XA 2FBAA 3M00A 2WVZA 2E2UA 1AVKA 3VDAA 1JS4A 1KZPB 4D94A 2E2TA 1JYVA 1TNOB 3S9VA 1N23A 1HV6A 3WKFA 1W4NA 1HZFA 1LOHA 3MUZ1 3E37B 3GLYA 1HWWA 2XN2A 2P0VA 3T0UA 1H3CA 3A24A 1HXAA 5EATA 3TY1A 3NNBA 1H37A 2A8ZA 4BOJA 2WYIA 1OACA 2JKAA 1FO3A 1N9EA 1NC5A 1RWFA 1QALA 2E22A 2ONGA 4OZVA 1K72A 1HN0A 3X3ZA 4L6XA 5IM1A 1LD7B 2WIIB 1NS4A 2CFDA 3EJTA 2HTBA 3ACSA 2QNOA 2B4FA 1D8DB 3Q7AB 3S4CA 3Q1NA 3KIIA 1JYXA 3A0OA 1OJNA 5EAUA 1IQYA 4D8OA 1IS9A 2F1BA 1JZ3A 5ILZA 3KBUC 3WKIA 1XWQA 3EZ8A 4Q88A 3NBJA 2WVXB 1FAEA 1XWTA 4FJQA 4MMIA 2C11A 4KFFA 1FO2A 4DUXA 3BVTA 2FUQA 4D72A 2CWVA 4GTPB 2H6IB 3I3BA 1W5ZA 1TXKA 3M71A 1G87A 2V3PA 2B39A 3M72A 3Q73B 1GXMA 4EV5A 3Q79B 1RW9A 3VDBA 3M77A 2JF4A 3M7EA 5A1AA 3M73A 3VD7A 4GTSB 4FXKB 2CG1A 1MMUA 1G9GA 1L1YA 4D6HA 1UI7A 3NJVA 4ZRQA 5MEHA 2ZL8A 5ILHA 1FT1B 1MMYA 1QAFA 4C1SA 3M02A 2CFLA 3UD1A 3PZ1B 1W3YA 1NSUA 2I07B 2JKEA 1F1SA 1KREA 1LF9A 4AQ0A 2F1AA 4CJ0A 3QFYA 1UT9A 2AHFA 2XHNA 3W5MA 1X1IA 4D1IA 1K1XA 1NI1B 1N7OA 4LNBB 3W7WA 1D6UA 2WO0A 1V5DA 3SXXA 1IVXA 1SPUA 4BZGA 3EQAA 4V1SA 1QX1A 2EADA 2JKPA 2V8KA 3E30B 1RWHA 5DHIA 3BLCA 1A2VA 3EUVB 1TU5A 1HXGA 4GTRB 2CISA 3E32B 3OBAA 2OOVC 3GT5A 3ANKA 3A3VA 3NFVA 1NSZA 2WZSA 2Y73A 3H7LA 4D6IA 3QG0A 2WYHA 1NSMA 1NS0A 1QAZA 3S4DA 3M7BA 3PZ2B 3EU8A 1W6CA 2WMJA 1EGUA 4AYQA 5IL3A 1OJOA 2FUTA 1LXKA 1X1HA 5FO9B 1TQVA 3E34B 3NBBA 4FNRA 3BVVA 1JZ7A 3TF4A 3SDTA 2OW7A 5DHKA 2YFOA 1JRQA 1KSCA 1QWUA 2D8LA 3EJRA 1RKYA 1HMUA 4Q2BA 3SDUA 5FO8B 1F9DA 1IVUA 5ILYA 1F9OA 5IL8A 4WVBA 1JZ2A 3DSXB 3H3KA 2F18A 2RGKA 3M7CA 4M76A 5GZKA 3HXCB 4D6EA 1LURA 4KFEA 3QT3A 1IA6A 3DSTB 1HN1A 2ONHA 1NKGA 1TN7B 4OJZA 1PS3A 1N4QB 2W0QA 1LTXB 1DOGA 3D3IA 5IK9A 1QAKA 4MMHA 2AFAA 4TXTA 1MMZA 3SAEA 1N94B 2V8JA 2WDAA 5C05A 1YGAA 4D4DA 1NSXA 4GL3A 3VD4A 3Q7FB 2XSGA 1WMOA 1NL4B 2V8IA 5JMDA 3F59A 2WW2A 3DX3A 5ILIA 3DPYB 2JG0A 3T2PA 4D6JA 3D5SA 3PYBA 1TNYB 1QBQB 1CLCA 3ON6A 5EASA 4TF4A 3SQCA 3D4YA 1Z45A 3WVFA 1N4SB 2ZIRB 1NXCA 3M78A 1RQ5A 4L9PB 1O7DD 1N4PB 1H13A 2WW0A 4LNGB 3VSNA 1IVWA 3OB8A 1JZ4A 2BRPA 1LD8B 3OEDA 2CWUA 3HI7A 1HM3A 2A73B 3ANIA 2F7QA 1HTYA 1RWAA 3HXEB 3WFAA 3E33B 1EKMA 3QRYA 1AGMA 1NS7A 4J5TA
chains in the Genus database with same CATH topology
2HTAA 1RW9A 3VDBA 4BZEA 3VD3A 3J7HA 5A1AA 2WMFA 3VD7A 1JOVA 2WMIB 3K25A 1OJMA 1N7QA 1MMUA 4D6HA 3NJVA 2WVXA 3CZJA 3T09A 4D71A 3BGAA 1F4HA 2WW3A 1SNZA 1HM2A 4NEIA 1MMYA 2WMKA 1W3YA 1NSUA 1NSVA 2JKEA 3I3DA 1F1SA 1LF9A 2D73A 4AQ0A 2BRWA 3DYMA 1L7JA 1MN0A 2XHNA 1X1IA 1K1XA 1N7OA 1LXMA 1F4AA 1JZ6A 3VD5A 4BZGA 3VSMA 4OK4A 2ZXQA 2WW1A 4D6GA 3T0BA 3T0AA 2JKPA 3T2OA 1JZ8A 2WMIA 1RWHA 3BLCA 3E80A 1J0MA 1N7PA 4OZWA 3DYPA 4BZFA 2CISA 2ZQ0A 1JYWA 3OBAA 4BZHA 2X03A 1PX3A 3MV01 3ECQA 3NFVA 4D6FA 1NSZA 3VDCA 2WZSA 3I3EA 2BRVX 3E7JA 2CIRA 4D6IA 3T2QA 4D6CA 2WCOA 1NSMA 1NS0A 3BS6A 1QAZA 2WMJA 1RWCA 3NJXA 1EGUA 4DUWA 3IAPA 1OJOA 2FUTA 1LXKA 1X1HA 3IAQA 2WMHA 1K1YA 1JZ7A 3DCDA 1JZ5A 5E1QA 1OJPA 1MMXA 2WVZA 3VDAA 1NS2A 1JYVA 1HMUA 1HV6A 3SEPA 1LOHA 5JMFA 3MUZ1 3T08A 1JZ2A 1LF6A 4D6EA 1LURA 3A24A 3AFLA 3MUY1 3TY1A 3NNBA 4E1YA 1J0NA 1HN1A 1NKGA 3E1F1 1L7KA 4OJZA 2JKAA 1RWFA 4F13A 2E22A 2WVYA 4OZVA 1HN0A 2CIQA 4RNLA 1NS4A 4MMHA 3MV11 1MMZA 2HTBA 1JYNA 3MWXA 1K1WA 3OS7A 2WDAA 3Q1NA 1YGAA 1NSXA 1N7RA 1JYXA 1HMWA 3VD4A 1NSSA 2XSGA 4D6DA 3A0OA 1OJNA 1C82A 5JMDA 3T0DA 1YQ2A 3DYOA 1ULVA 2WW2A 1JZ3A 1UG9A 1CB8A 3DECA 4F10A 1NS8A 3T2PA 2WVXB 4MMIA 4DUXA 1N7NA 4D6JA 3VD9A 4FNVA 1F9GA 2E24A 2FUQA 4D72A 1Z45A 3WVFA 1DP0A 3I3BA 4OK2A 3IMHA 1SO0A 4TTGA 2WW0A 3VSNA 1RWGA 2WMGA 1TXKA 3NREA 3OB8A 2BRPA 4DUVA 1JZ4A 1HM3A 2Q1FA 1PX4A 1RWAA 3WFAA 1I8QA 1NSRA 1NS7A 1X1JA 4J5TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HTA A;  1RW9 A;  3VDB A;  4BZE A;  3VD3 A;  3J7H A;  5A1A A;  2WMF A;  3VD7 A;  1JOV A;  2WMI B;  3K25 A;  1OJM A;  1N7Q A;  1MMU A;  4D6H A;  3NJV A;  2WVX A;  3CZJ A;  3T09 A;  4D71 A;  3BGA A;  1F4H A;  2WW3 A;  1SNZ A;  1HM2 A;  4NEI A;  1MMY A;  2WMK A;  1W3Y A;  1NSU A;  1NSV A;  2JKE A;  3I3D A;  1F1S A;  1LF9 A;  2D73 A;  4AQ0 A;  2BRW A;  3DYM A;  1L7J A;  1MN0 A;  2XHN A;  1X1I A;  1K1X A;  1N7O A;  1LXM A;  1F4A A;  1JZ6 A;  3VD5 A;  4BZG A;  3VSM A;  4OK4 A;  2ZXQ A;  2WW1 A;  4D6G A;  3T0B A;  3T0A A;  2JKP A;  3T2O A;  1JZ8 A;  2WMI A;  1RWH A;  3E80 A;  1J0M A;  1N7P A;  4OZW A;  3DYP A;  4BZF A;  2CIS A;  2ZQ0 A;  1JYW A;  3OBA A;  4BZH A;  2X03 A;  1PX3 A;  3MV0 1;  3ECQ A;  3NFV A;  4D6F A;  1NSZ A;  3VDC A;  2WZS A;  3I3E A;  2BRV X;  3E7J A;  2CIR A;  4D6I A;  3T2Q A;  4D6C A;  2WCO A;  1NSM A;  1NS0 A;  1QAZ A;  2WMJ A;  1RWC A;  3NJX A;  1EGU A;  4DUW A;  3IAP A;  1OJO A;  2FUT A;  1LXK A;  1X1H A;  3IAQ A;  2WMH A;  1K1Y A;  1JZ7 A;  3DCD A;  1JZ5 A;  5E1Q A;  1OJP A;  1MMX A;  2WVZ A;  3VDA A;  1NS2 A;  1JYV A;  1HMU A;  1HV6 A;  3SEP A;  1LOH A;  5JMF A;  3MUZ 1;  3T08 A;  1JZ2 A;  1LF6 A;  4D6E A;  1LUR A;  3A24 A;  3AFL A;  3MUY 1;  3NNB A;  4E1Y A;  1J0N A;  1HN1 A;  1NKG A;  3E1F 1;  1L7K A;  4OJZ A;  2JKA A;  1RWF A;  4F13 A;  2E22 A;  2WVY A;  4OZV A;  1HN0 A;  2CIQ A;  4RNL A;  1NS4 A;  4MMH A;  3MV1 1;  1MMZ A;  2HTB A;  1JYN A;  3MWX A;  1K1W A;  3OS7 A;  2WDA A;  3Q1N A;  1YGA A;  1NSX A;  1N7R A;  1JYX A;  1HMW A;  3VD4 A;  1NSS A;  2XSG A;  4D6D A;  3A0O A;  1OJN A;  1C82 A;  5JMD A;  3T0D A;  1YQ2 A;  3DYO A;  1ULV A;  2WW2 A;  1JZ3 A;  1UG9 A;  1CB8 A;  3DEC A;  4F10 A;  1NS8 A;  3T2P A;  2WVX B;  4MMI A;  4DUX A;  1N7N A;  4D6J A;  3VD9 A;  4FNV A;  1F9G A;  2E24 A;  2FUQ A;  4D72 A;  1Z45 A;  1DP0 A;  3I3B A;  4OK2 A;  3IMH A;  1SO0 A;  4TTG A;  2WW0 A;  3VSN A;  1RWG A;  2WMG A;  1TXK A;  3NRE A;  3OB8 A;  2BRP A;  4DUV A;  1JZ4 A;  1HM3 A;  2Q1F A;  1PX4 A;  1RWA A;  3WFA A;  1I8Q A;  1NSR A;  1NS7 A;  1X1J A; 
#chains in the Genus database with same CATH topology
 2HTA A;  3HIG A;  3WKG A;  1WMP A;  4BZE A;  5IKA A;  3J7H A;  2WMI B;  3K25 A;  1KWF A;  3AMO A;  1HCU A;  1N1B A;  4ZG8 A;  1N4R B;  3M01 A;  1WU4 A;  3WUX A;  5AGD A;  1O1S B;  2NOJ A;  5M7Y A;  1WU6 A;  4V1R A;  4D71 A;  3BGA A;  3T09 A;  4ZRP A;  2EAC A;  4WVC A;  1RJO A;  4FUS A;  4DLO A;  2CFK A;  3M75 A;  1D8E B;  3UD2 A;  2OOV A;  1TNB B;  3WA2 X;  3HXD B;  2D73 A;  1X81 B;  2BRW A;  4AYO A;  4DOD A;  4JJJ A;  2GZ6 A;  2ZIS B;  1MN0 A;  3DYM A;  1O79 A;  1TNZ B;  2D5J A;  2DRO A;  4D4A A;  3QT9 A;  2XFG A;  5IK6 A;  1H14 A;  1F4A A;  2V3N A;  3KSL B;  3N0G A;  3X41 A;  4D6G A;  1FBO A;  5ILJ A;  2RI9 A;  4FNT A;  1W6G A;  2DRS A;  3EU5 B;  4DI5 A;  3HII A;  1J0M A;  3BUD A;  4BZF A;  4BZH A;  5KKB A;  3ECQ A;  4D6F A;  3VDC A;  3I3E A;  2C10 A;  2BRV X;  1H39 A;  3E7J A;  1XW2 A;  3MI6 A;  4D6C A;  2WCO A;  3BS6 A;  4Z4L A;  3LZ9 A;  1D6Z A;  2Y74 A;  1WU5 A;  2JJB A;  3PMM A;  1JCQ B;  1KKT A;  4YDE B;  4ZH5 A;  5E2J A;  1O6R A;  3NJX A;  3QDE A;  3IAP A;  2BB6 A;  4BTW A;  5GY3 A;  1O1R B;  3IAQ A;  3RJ3 A;  2CQT A;  3P5R A;  3BVX A;  4FNS A;  1V5C A;  3DCD A;  3P5P A;  4CE7 A;  1OJP A;  1MMX A;  3E73 A;  2NVP A;  1IU7 A;  1LVN A;  2AHG A;  1NS2 A;  1KS8 A;  4WVA A;  1N20 A;  1H3B A;  5JMF A;  1SIH A;  1H3A A;  3QR8 A;  3DX2 A;  4FNP A;  3SEP A;  3T08 A;  3G6J B;  1WZZ A;  2F0Y B;  3WIW A;  4GTV B;  1SA4 B;  3ACT A;  3X40 A;  1GSZ A;  4E1Y A;  2OW6 A;  1AV4 A;  4D4B A;  3E1F 1;  1L7K A;  1JCS B;  4F13 A;  3RRS A;  2F6D A;  2WVY A;  4EHM B;  4K3A A;  1TQT A;  2CIQ A;  4RNL A;  3N0F A;  2WOF A;  1JYN A;  3MWX A;  2VN4 A;  4MU9 A;  4LIX A;  2PN5 A;  1FT2 B;  2KXR A;  3QXQ A;  1V7W A;  4D4C A;  1IA7 A;  1HMW A;  3WIR A;  1NSS A;  3M76 A;  4D6D A;  1WMN A;  1C82 A;  3P2C A;  1H36 A;  3T0D A;  1TN8 B;  4L0G A;  3GZK A;  3N9H A;  3PYA A;  3W7U A;  3DYO A;  5M7I A;  3D5R A;  1UG9 A;  2DRQ A;  3DDG A;  1CB8 A;  1NS8 A;  3S4A A;  3CIH A;  1KSI A;  2CQS A;  4GTT B;  3WA3 A;  1N7N A;  3VD9 A;  1DP0 A;  3W7X A;  3BUB A;  4OK2 A;  4TTG A;  4DUV A;  3SFX B;  1IQX A;  1GAI A;  2CFG A;  3PGB A;  3BUI A;  1I8Q A;  2VN7 A;  3DSS B;  3CV5 A;  3RX8 A;  1HXC A;  3T0A A;  2XN0 A;  1US1 A;  3VD3 A;  3X3Y A;  3W5N A;  2WMF A;  1JOV A;  1D6Y A;  1FBW A;  2J5C A;  1W2Z A;  1H35 A;  3HXF B;  2RDY A;  4KKI A;  2WVX A;  4RNQ A;  2ZZR A;  4K35 A;  1L2A A;  1F4H A;  2WW3 A;  3K11 A;  1TQU A;  1HM2 A;  4NEI A;  1N24 A;  2SQC A;  2WMK A;  5JPN B;  1N22 A;  5IKH A;  1TQS A;  1FCE A;  2XN1 A;  1HXK A;  2FUZ A;  3M74 A;  5ILK A;  2H6H B;  5ILD A;  2XQW A;  4KFD A;  1N21 A;  1IVV A;  4DLQ A;  3EJQ A;  5CZL A;  3SDQ A;  3W7S A;  2R2L B;  3ALA A;  4FNU A;  2DRR A;  3SFY B;  2WIN B;  2GOX A;  1H54 A;  4OK4 A;  3VSM A;  2WW1 A;  2ZXQ A;  3T0B A;  3T2O A;  1JZ8 A;  1DL2 A;  3BVU A;  3E80 A;  5KBP A;  2WGQ A;  1W6K A;  3DYP A;  2ZQ0 A;  3DX0 A;  1W7C A;  2X03 A;  1PX3 A;  4KKJ A;  1G6I A;  3T2Q A;  2WY8 A;  4YDO B;  4GAX A;  2IEJ B;  4ONT A;  1UI8 A;  4XUV A;  3X3X A;  3U7V A;  1KRF A;  4DUW A;  4FXG B;  1KSD A;  1N1Z A;  3H2W A;  3SDR A;  1N95 B;  3K5T A;  3K7X A;  3S4B A;  3Q75 B;  1JZ5 A;  3WKH A;  1KFG A;  4KTR A;  3RX7 A;  3EJP A;  1O5M B;  3Q78 B;  5FO7 B;  3DX1 A;  3EJS A;  5CA3 A;  1HX9 A;  4WU0 A;  3D52 A;  4BTY A;  5FOB B;  1S63 B;  2H6G B;  2XWJ B;  1LF6 A;  2OQE C;  3REN A;  2CWT A;  3D51 A;  3AFL A;  3MUY 1;  1TF4 A;  2F7O A;  3OXU A;  2CFW A;  4ZH1 A;  3BUQ A;  1J0N A;  2WOH A;  2PMV A;  2FYV A;  3RX5 A;  2BBC A;  4KTP A;  3C72 B;  2CG0 A;  4UFC A;  3DSW B;  1H12 A;  5JPM B;  1N9A B;  2ZBL A;  3WC3 A;  2PNC A;  1FPP B;  3MV1 1;  3KSQ B;  3LOY A;  1K1W A;  3OS7 A;  3WIQ A;  1V7V A;  1N7R A;  1JCR B;  2Z07 A;  4GTQ B;  1S64 B;  4DOE A;  2FV0 A;  3ANJ A;  3SDV A;  3BLB A;  1GHQ A;  1TQW A;  1PU4 A;  3QPF A;  2KXS A;  2BT3 A;  5CD2 A;  1G9J A;  3BUP A;  2D1W A;  1YQ2 A;  3D4Z A;  3CZS A;  1ULV A;  2E2V A;  3AMO B;  4FNQ A;  4AYP A;  3DEC A;  4F10 A;  1TNU B;  1MZC B;  4D1J A;  2G02 A;  2H6F B;  3W7T A;  3M7L A;  1F9G A;  1VD5 A;  2E24 A;  4FNV A;  5DGQ A;  2YX9 A;  3DDF A;  2EAB A;  3MPH A;  3IMH A;  4BOK A;  1SO0 A;  2WMG A;  1RWG A;  1SQC A;  4BTX A;  3NRE A;  5IK0 A;  2WYN A;  1W6J A;  1X9D A;  1SA5 B;  3KBT C;  2Q1F A;  1FMI A;  1GLM A;  1PX4 A;  3CZN A;  3SX1 A;  3PZ3 B;  1FP3 A;  1TN6 B;  3VW5 A;  1NSR A;  3BVW A;  4QT9 A;  3KQ4 A;  1X1J A;  4EV2 A;  3CU7 A;  3DSU B;  3D50 A;  1KZO B;  3DSV B;  2EAE A;  1O1T B;  4CJ1 A;  2BB5 A;  3E6U A;  3G4F A;  1OJM A;  1N7Q A;  4AYR A;  2WY7 A;  1AYX A;  3PQI A;  3DRA B;  3CZJ A;  3RSY A;  1SNZ A;  1R76 A;  3HXB B;  1AVL A;  1QWN A;  1CEM A;  1UMP A;  1NSV A;  2ALW A;  3I3D A;  4EL8 A;  1DYU A;  1L7J A;  1SII A;  2BED B;  4GTO B;  4Z4J A;  1GA2 A;  1O6H A;  1O6Q A;  1LXM A;  1JZ6 A;  1GAH A;  2FV1 A;  5GW7 A;  3VD5 A;  3X17 A;  2F7P A;  1C3D A;  1DCE B;  3LVT A;  2RI8 A;  2WMI A;  5DGR A;  1N7P A;  3QSP A;  3QFZ A;  4OZW A;  4YCR A;  2OKX A;  3PZ4 B;  1R34 A;  1JYW A;  3AFJ A;  4MBG B;  4GTM B;  3EJU A;  3MV0 1;  3QWT A;  3T33 A;  3X42 A;  2CIR A;  1GXN A;  2G0D A;  3QXF A;  2YIK A;  1R33 A;  2YFN A;  1RWC A;  2F7R A;  2OQE A;  3KLS A;  1GXO A;  1QSJ A;  1QQF A;  3G4D A;  3DX4 A;  2WMH A;  4LNV A;  3KN4 A;  1K1Y A;  2GH4 A;  2XWB B;  3VXD A;  5E1Q A;  1V7X A;  2FBA A;  3M00 A;  2WVZ A;  2E2U A;  1AVK A;  3VDA A;  1JS4 A;  1KZP B;  4D94 A;  2E2T A;  1JYV A;  1TNO B;  3S9V A;  1N23 A;  1HV6 A;  3WKF A;  1W4N A;  1HZF A;  1LOH A;  3MUZ 1;  3E37 B;  3GLY A;  1HWW A;  2XN2 A;  2P0V A;  3T0U A;  1H3C A;  3A24 A;  1HXA A;  5EAT A;  3TY1 A;  3NNB A;  1H37 A;  2A8Z A;  4BOJ A;  2WYI A;  1OAC A;  2JKA A;  1FO3 A;  1N9E A;  1NC5 A;  1RWF A;  1QAL A;  2E22 A;  2ONG A;  4OZV A;  1K72 A;  1HN0 A;  3X3Z A;  4L6X A;  5IM1 A;  1LD7 B;  2WII B;  1NS4 A;  2CFD A;  3EJT A;  2HTB A;  3ACS A;  2QNO A;  2B4F A;  1D8D B;  3Q7A B;  3S4C A;  3Q1N A;  3KII A;  1JYX A;  3A0O A;  1OJN A;  5EAU A;  1IQY A;  4D8O A;  1IS9 A;  2F1B A;  1JZ3 A;  5ILZ A;  3KBU C;  3WKI A;  1XWQ A;  3EZ8 A;  4Q88 A;  3NBJ A;  2WVX B;  1FAE A;  1XWT A;  4FJQ A;  4MMI A;  2C11 A;  4KFF A;  1FO2 A;  4DUX A;  3BVT A;  2FUQ A;  4D72 A;  2CWV A;  4GTP B;  2H6I B;  3I3B A;  1W5Z A;  1TXK A;  3M71 A;  1G87 A;  2V3P A;  2B39 A;  3M72 A;  3Q73 B;  1GXM A;  4EV5 A;  3Q79 B;  1RW9 A;  3VDB A;  3M77 A;  2JF4 A;  3M7E A;  5A1A A;  3M73 A;  3VD7 A;  4GTS B;  4FXK B;  2CG1 A;  1MMU A;  1G9G A;  1L1Y A;  4D6H A;  1UI7 A;  3NJV A;  4ZRQ A;  5MEH A;  2ZL8 A;  5ILH A;  1FT1 B;  1MMY A;  1QAF A;  4C1S A;  3M02 A;  2CFL A;  3UD1 A;  3PZ1 B;  1W3Y A;  1NSU A;  2I07 B;  2JKE A;  1F1S A;  1KRE A;  1LF9 A;  4AQ0 A;  2F1A A;  4CJ0 A;  3QFY A;  1UT9 A;  2AHF A;  2XHN A;  3W5M A;  1X1I A;  4D1I A;  1K1X A;  1NI1 B;  1N7O A;  4LNB B;  3W7W A;  1D6U A;  2WO0 A;  1V5D A;  3SXX A;  1IVX A;  1SPU A;  4BZG A;  3EQA A;  4V1S A;  1QX1 A;  2EAD A;  2JKP A;  2V8K A;  3E30 B;  1RWH A;  5DHI A;  3BLC A;  1A2V A;  3EUV B;  1TU5 A;  1HXG A;  4GTR B;  2CIS A;  3E32 B;  3OBA A;  2OOV C;  3GT5 A;  3ANK A;  3A3V A;  3NFV A;  1NSZ A;  2WZS A;  2Y73 A;  3H7L A;  4D6I A;  3QG0 A;  2WYH A;  1NSM A;  1NS0 A;  1QAZ A;  3S4D A;  3M7B A;  3PZ2 B;  3EU8 A;  1W6C A;  2WMJ A;  1EGU A;  4AYQ A;  5IL3 A;  1OJO A;  2FUT A;  1LXK A;  1X1H A;  5FO9 B;  1TQV A;  3E34 B;  3NBB A;  4FNR A;  3BVV A;  1JZ7 A;  3TF4 A;  3SDT A;  2OW7 A;  5DHK A;  2YFO A;  1JRQ A;  1KSC A;  1QWU A;  2D8L A;  3EJR A;  1RKY A;  1HMU A;  4Q2B A;  3SDU A;  5FO8 B;  1F9D A;  1IVU A;  5ILY A;  1F9O A;  5IL8 A;  4WVB A;  1JZ2 A;  3DSX B;  3H3K A;  2F18 A;  2RGK A;  3M7C A;  4M76 A;  5GZK A;  3HXC B;  4D6E A;  1LUR A;  4KFE A;  3QT3 A;  1IA6 A;  3DST B;  1HN1 A;  2ONH A;  1NKG A;  1TN7 B;  4OJZ A;  1PS3 A;  1N4Q B;  2W0Q A;  1LTX B;  1DOG A;  3D3I A;  5IK9 A;  1QAK A;  4MMH A;  2AFA A;  4TXT A;  1MMZ A;  3SAE A;  1N94 B;  2V8J A;  2WDA A;  5C05 A;  1YGA A;  4D4D A;  1NSX A;  4GL3 A;  3VD4 A;  3Q7F B;  2XSG A;  1WMO A;  1NL4 B;  2V8I A;  5JMD A;  3F59 A;  2WW2 A;  3DX3 A;  5ILI A;  3DPY B;  2JG0 A;  3T2P A;  4D6J A;  3D5S A;  3PYB A;  1TNY B;  1QBQ B;  1CLC A;  3ON6 A;  5EAS A;  4TF4 A;  3SQC A;  3D4Y A;  1Z45 A;  3WVF A;  1N4S B;  2ZIR B;  1NXC A;  3M78 A;  1RQ5 A;  4L9P B;  1O7D D;  1N4P B;  1H13 A;  2WW0 A;  4LNG B;  3VSN A;  1IVW A;  3OB8 A;  1JZ4 A;  2BRP A;  1LD8 B;  3OED A;  2CWU A;  3HI7 A;  1HM3 A;  2A73 B;  3ANI A;  2F7Q A;  1HTY A;  1RWA A;  3HXE B;  3WFA A;  3E33 B;  1EKM A;  3QRY A;  1AGM A;  1NS7 A;  4J5T A; 
#chains in the Genus database with same CATH homology
 2HTA A;  1RW9 A;  3VDB A;  4BZE A;  3VD3 A;  3J7H A;  5A1A A;  2WMF A;  3VD7 A;  1JOV A;  2WMI B;  3K25 A;  1OJM A;  1N7Q A;  1MMU A;  4D6H A;  3NJV A;  2WVX A;  3CZJ A;  3T09 A;  4D71 A;  3BGA A;  1F4H A;  2WW3 A;  1SNZ A;  1HM2 A;  4NEI A;  1MMY A;  2WMK A;  1W3Y A;  1NSU A;  1NSV A;  2JKE A;  3I3D A;  1F1S A;  1LF9 A;  2D73 A;  4AQ0 A;  2BRW A;  3DYM A;  1L7J A;  1MN0 A;  2XHN A;  1X1I A;  1K1X A;  1N7O A;  1LXM A;  1F4A A;  1JZ6 A;  3VD5 A;  4BZG A;  3VSM A;  4OK4 A;  2ZXQ A;  2WW1 A;  4D6G A;  3T0B A;  3T0A A;  2JKP A;  3T2O A;  1JZ8 A;  2WMI A;  1RWH A;  3BLC A;  3E80 A;  1J0M A;  1N7P A;  4OZW A;  3DYP A;  4BZF A;  2CIS A;  2ZQ0 A;  1JYW A;  3OBA A;  4BZH A;  2X03 A;  1PX3 A;  3MV0 1;  3ECQ A;  3NFV A;  4D6F A;  1NSZ A;  3VDC A;  2WZS A;  3I3E A;  2BRV X;  3E7J A;  2CIR A;  4D6I A;  3T2Q A;  4D6C A;  2WCO A;  1NSM A;  1NS0 A;  3BS6 A;  1QAZ A;  2WMJ A;  1RWC A;  3NJX A;  1EGU A;  4DUW A;  3IAP A;  1OJO A;  2FUT A;  1LXK A;  1X1H A;  3IAQ A;  2WMH A;  1K1Y A;  1JZ7 A;  3DCD A;  1JZ5 A;  5E1Q A;  1OJP A;  1MMX A;  2WVZ A;  3VDA A;  1NS2 A;  1JYV A;  1HMU A;  1HV6 A;  3SEP A;  1LOH A;  5JMF A;  3MUZ 1;  3T08 A;  1JZ2 A;  1LF6 A;  4D6E A;  1LUR A;  3A24 A;  3AFL A;  3MUY 1;  3TY1 A;  3NNB A;  4E1Y A;  1J0N A;  1HN1 A;  1NKG A;  3E1F 1;  1L7K A;  4OJZ A;  2JKA A;  1RWF A;  4F13 A;  2E22 A;  2WVY A;  4OZV A;  1HN0 A;  2CIQ A;  4RNL A;  1NS4 A;  4MMH A;  3MV1 1;  1MMZ A;  2HTB A;  1JYN A;  3MWX A;  1K1W A;  3OS7 A;  2WDA A;  3Q1N A;  1YGA A;  1NSX A;  1N7R A;  1JYX A;  1HMW A;  3VD4 A;  1NSS A;  2XSG A;  4D6D A;  3A0O A;  1OJN A;  1C82 A;  5JMD A;  3T0D A;  1YQ2 A;  3DYO A;  1ULV A;  2WW2 A;  1JZ3 A;  1UG9 A;  1CB8 A;  3DEC A;  4F10 A;  1NS8 A;  3T2P A;  2WVX B;  4MMI A;  4DUX A;  1N7N A;  4D6J A;  3VD9 A;  4FNV A;  1F9G A;  2E24 A;  2FUQ A;  4D72 A;  1Z45 A;  3WVF A;  1DP0 A;  3I3B A;  4OK2 A;  3IMH A;  1SO0 A;  4TTG A;  2WW0 A;  3VSN A;  1RWG A;  2WMG A;  1TXK A;  3NRE A;  3OB8 A;  2BRP A;  4DUV A;  1JZ4 A;  1HM3 A;  2Q1F A;  1PX4 A;  1RWA A;  3WFA A;  1I8Q A;  1NSR A;  1NS7 A;  1X1J A;  4J5T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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