2WDAA

The x-ray structure of the streptomyces coelicolor a3 chondroitin ac lyase in complex with chondroitin sulphate
Total Genus 261
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces violaceoruber
molecule tags Lyase
molecule keywords PUTATIVE SECRETED LYASE
total genus 261
structure length 742
sequence length 742
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2wdaA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2wdaA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2wdaA02
3MUZ1 1MMXA 4D6EA 4MMIA 1X1IA 1JZ2A 4OK4A 3K25A 3I3EA 4F10A 3VDAA 3OS7A 1JZ7A 1DP0A 1N7PA 2JKPA 4D6JA 1LURA 2HTBA 4F13A 2JKEA 3SEPA 3E1F1 2ZQ0A 1UG9A 3BGAA 4RNLA 1JZ8A 3VSMA 4FNVA 1J0MA 4OJZA 3T0AA 4TTGA 2WW0A 4D6HA 1NS7A 2ZXQA 3T2OA 1JYVA 1MMUA 1JZ6A 1HM3A 3IAPA 1RW9A 1LF6A 2FUQA 2D73A 1F4HA 1SNZA 4OK2A 1RWHA 1HMWA 1JZ3A 1N7QA 1NSRA 2BRVX 1OJOA 1PX3A 3Q1NA 3CZJA 5JMDA 4D6FA 1NS0A 3ECQA 1OJPA 3T09A 3OBAA 2BRPA 3IMHA 4DUXA 3WFAA 2WMHA 2XHNA 1RWFA 3T2PA 4D6GA 3DYPA 3NJXA 4BZFA 3A24A 3NREA 2WMIB 1SO0A 1NSMA 1HMUA 1LF9A 1F1SA 2FUTA 2WVZA 1MN0A 1HV6A 1W3YA 2WMJA 1PX4A 1NSZA 1EGUA 1HN0A 1MMZA 1LOHA 1HN1A 2WMIA 3I3DA 3VDCA 4BZEA 2E24A 2WW3A 1YGAA 4D6DA 3AFLA 3VD4A 3VDBA 4D6CA 1JZ4A 4OZVA 2CISA 1JYNA 1NKGA 1N7NA 3A0OA 1F9GA 2WMKA 1OJMA 3VD7A 3VSNA 2CIRA 3MV11 3VD9A 3T0BA 1K1XA 3DECA 4D6IA 2HTAA 3E7JA 1TXKA 2JKAA 2X03A 2WW2A 1NSSA 1Z45A 1F4AA 1CB8A 1HM2A 2CIQA 1I8QA 4MMHA 4BZGA 3MV01 2WVYA 2Q1FA 2WMGA 1N7OA 2WW1A 1NSUA 1JYXA 3NFVA 1NSXA 1RWGA 1ULVA 3MWXA 1NS8A 2WZSA 1NS4A 5E1QA 2WDAA 3DYMA 4D72A 1JOVA 3T0DA 3MUY1 2WMFA 3J7HA 4NEIA 1L7JA 3VD3A 1L7KA 3VD5A 4DUWA 1J0NA 1NSVA 3NNBA 3IAQA 3T2QA 1C82A 1OJNA 1QAZA 1RWCA 1K1WA 1X1HA 5A1AA 4D71A 1K1YA 1NS2A 4E1YA 2WVXB 1LXMA 4OZWA 1N7RA 3I3BA 2BRWA 2E22A 5JMFA 3OB8A 3E80A 4BZHA 1LXKA 1MMYA 1YQ2A 3NJVA 3DCDA 1JYWA 4AQ0A 3DYOA 1RWAA 1X1JA 3T08A 1JZ5A 4DUVA 2WVXA 2XSGA 2WCOA
chains in the Genus database with same CATH superfamily
2A8ZA 3UD1A 3AMOA 4D6EA 1W4NA 3ACSA 1WU6A 2KXRA 1TNBB 4GL3A 2FYVA 2C11A 4DODA 2R2LB 4V1SA 1HCUA 2E2UA 1NC5A 3Q7AB 3OS7A 4K3AA 1JZ7A 1DL2A 1N4RB 2H6IB 3RX7A 4D6JA 3HXDB 2HTBA 2WY8A 4F13A 4MBGB 1FT1B 1UG9A 4GTPB 3WIRA 1D6UA 2CFKA 3RX5A 3BGAA 4FNRA 4RNLA 3PZ3B 3NBJA 3SDQA 1J0MA 3SDVA 3SDTA 2OKXA 3T0AA 1KZPB 3S4BA 1H3AA 3W5MA 4D6HA 2WW0A 3T2OA 3E30B 1JYVA 1HZFA 3DDFA 1WZZA 2G02A 3BVUA 1F9OA 2V3PA 1F9DA 1WU5A 2PN5A 1KSDA 3D5RA 2RDYA 3Q73B 1HMWA 1TNZB 1N7QA 3DSSB 1NSRA 3Q1NA 1TQTA 5CZLA 1A2VA 1O6RA 3X3YA 3DPYB 4GTVB 4M76A 3ECQA 3T09A 4FXKB 1GSZA 5IL3A 1O7DD 3N0GA 5IL8A 1QQFA 1HXCA 4D6GA 1WMOA 3DYPA 2B39A 3ANJA 2NOJA 2WMIB 2BBCA 1HMUA 1W6GA 3BVWA 2WVZA 1N4SB 2ZZRA 2IEJB 3PZ4B 1TU5A 4KKJA 1EGUA 3U7VA 3KIIA 1V7VA 1QWUA 3HXFB 1VD5A 1YGAA 3VDBA 4OZVA 1GXMA 4L0GA 2CISA 1UI8A 1NKGA 3A0OA 1F9GA 1N94B 2PMVA 4YDEB 2OQEC 4CE7A 2ZBLA 1OJMA 3K11A 1EKMA 3VD7A 3VSNA 3WKIA 2CIRA 3ANKA 4XUVA 3GZKA 3SFXB 3VD9A 4FXGB 1AV4A 5IKAA 3QPFA 2WW2A 2X03A 4AYRA 3X42A 2F0YB 3Q75B 1WMNA 1H3CA 1Z45A 2F1AA 3M76A 1JCQB 1QALA 4BOJA 1HM2A 4ZH5A 1V5CA 3G6JB 2WYHA 3RENA 1D6ZA 4D4AA 1QAFA 3WVFA 2Q1FA 1X81B 1N7OA 1TF4A 2J5CA 2WW1A 2WOHA 1UMPA 3VW5A 1ULVA 2H6FB 3MWXA 1X9DA 5ILDA 2EAEA 1N1BA 2WDAA 3J7HA 2CWTA 1TQSA 3D4ZA 1O6QA 1N4PB 4BTWA 1IVWA 1NSVA 3WIWA 1HXKA 1C82A 4EL8A 2CWVA 4BTYA 1IA7A 3E73A 2GZ6A 1N9EA 2WVXB 5ILKA 5M7IA 1N4QB 3X3XA 2BRWA 1SA5B 3S4AA 4KFFA 1TNOB 1LXKA 5FO9B 5IM1A 3NJVA 4TXTA 2BEDB 3DYOA 5AGDA 1X1JA 2GH4A 3Q7FB 1QX1A 4DUVA 2WCOA 1MMXA 4MMIA 3E32B 3QFZA 1X1IA 2E2TA 1L1YA 4D8OA 1JZ2A 4DI5A 3I3EA 3VDAA 1XWTA 3WA3A 5FOBB 1IVXA 3WKFA 3QRYA 3E1F1 3SEPA 1N20A 2DRSA 3LZ9A 1H3BA 2OOVA 1LD8B 4GTMB 1FAEA 2P0VA 3BVTA 4KTRA 1GHQA 1K72A 4Z4LA 1IA6A 2XN2A 4EV2A 1HXGA 2XQWA 4FNUA 4LIXA 3IAPA 4Z4JA 2FUQA 4GAXA 2PNCA 5IK0A 1SNZA 5C05A 4ZRPA 3W7UA 1RWHA 1PU4A 2Z07A 2CG1A 1KS8A 1OJOA 3H3KA 5JMDA 4D6FA 1OJPA 4FNSA 2CG0A 3C72B 3GT5A 5FO7B 1DCEB 1H54A 4GTOB 1LD7B 3Q79B 1R33A 1FPPB 2YX9A 3M7CA 3T2PA 3NJXA 3DSTB 1JCSB 3X17A 1N21A 3BLBA 2OOVC 1R34A 1SO0A 1NSMA 1HX9A 3W7SA 3D52A 3EU5B 1FO3A 1N9AB 2FUTA 2WMJA 2RI8A 5ILJA 4FJQA 3BUDA 4WU0A 2D5JA 2E24A 1O6HA 3AFLA 4D6CA 1OACA 2V8JA 1JZ4A 2WIIB 3BVVA 1W7CA 3SQCA 5ILIA 2XWBB 1JYNA 1N7NA 3EU8A 3KSQB 2F7PA 2WYNA 2ZISB 3KQ4A 1H13A 3M7BA 1SPUA 1G9GA 2BT3A 1W2ZA 3KBUC 1S64B 4CJ1A 3BLCA 1HXAA 3PYAA 1HWWA 5CD2A 4AYOA 5IK6A 1D8EB 1KSIA 1NSSA 2H6HB 3DSUB 5EATA 3CZNA 3T0UA 3PZ1B 2CIQA 2JJBA 3CZSA 1O1TB 1I8QA 3SXXA 3MV01 2WMGA 1H39A 1NSUA 1JYXA 3NFVA 3BUIA 1O5MB 1NS8A 3BVXA 3DSWB 1NS4A 3X3ZA 2CFLA 4D72A 3D4YA 3MUY1 3PMMA 1D6YA 1L7JA 3WKHA 4K35A 1GXOA 3QDEA 4D4BA 1L7KA 1C3DA 3VD5A 4DUWA 5DGRA 3F59A 3E33B 1OJNA 1RWCA 1K1WA 3PGBA 4ONTA 4D71A 1WU4A 4E1YA 4LNVA 4KFEA 1H12A 4OZWA 5DHKA 1O79A 2G0DA 3SDUA 4FNPA 1G87A 3E80A 3OB8A 2RI9A 1US1A 1DOGA 2B4FA 1L2AA 1JYWA 5MEHA 4WVCA 2CWUA 4FUSA 2WY7A 1W6KA 2XSGA 1QBQB 5CA3A 4D4CA 3MUZ1 2DRRA 3S4CA 3EJRA 4OK4A 4RNQA 1KFGA 2ONHA 1W5ZA 2F7QA 1UT9A 3WC3A 3EJQA 1H36A 4FNTA 2E2VA 3DDGA 3W7TA 1DP0A 2JKPA 3X41A 2CFWA 3M71A 4MU9A 1V5DA 4KKIA 1JZ8A 3N0FA 2EABA 1TQUA 4FNVA 1R76A 3GLYA 4TTGA 3LVTA 1NS7A 1JCRB 1FBOA 3MPHA 1LTXB 1MMUA 1HTYA 3EJTA 1GLMA 4Q88A 4DLQA 2F18A 2BRVX 2AFAA 3M7EA 3CZJA 3H2WA 3K7XA 1IVUA 2Y73A 3EJPA 3M78A 5E2JA 1FP3A 3BUPA 3IMHA 4DUXA 1KZOB 4Q2BA 5EAUA 2WMHA 1SIHA 4WVAA 3M73A 2CFDA 1GXNA 3DSXB 3M75A 4BZFA 4LNGB 3EQAA 3RJ3A 3SDRA 3M00A 1AVLA 2ALWA 4LNBB 5M7YA 2CFGA 3EJUA 1LVNA 2C10A 1O1RB 5KKBA 1KREA 1RKYA 1SQCA 1MN0A 1PX4A 1NSZA 3WKGA 1HN0A 1LOHA 2D8LA 5GY3A 1IU7A 1HN1A 3EUVB 3I3DA 3VDCA 3CU7A 4BZEA 1V7XA 1XWQA 3S4DA 1V7WA 3HIIA 4D94A 4GTQB 1XW2A 2WMKA 1FT2B 3UD2A 2FV0A 2ONGA 1N22A 3DX0A 3MV11 3D50A 4D1JA 3D3IA 4TF4A 4D4DA 4D6IA 1SIIA 2HTAA 3E7JA 3QFYA 4L9PB 1TXKA 2JKAA 1IQYA 2H6GB 2RGKA 2FBAA 1W6JA 1G9JA 3HI7A 3SX1A 1CB8A 3DRAB 2ZL8A 4UFCA 1GA2A 1TN7B 3H7LA 2WVYA 1AVKA 3QXFA 2D1WA 1IS9A 1NI1B 3OEDA 3QR8A 3D5SA 3CIHA 4GTRB 3VXDA 1CLCA 3T0DA 2WMFA 2CQTA 3ACTA 4NEIA 3M74A 3VD3A 2DROA 2FUZA 3T33A 1J0NA 3E6UA 2BB6A 2XN1A 3NNBA 3T2QA 2CQSA 2JF4A 1TNUB 4FNQA 1QAZA 1KWFA 1X1HA 2WYIA 3K5TA 1H37A 2XFGA 4BOKA 1DYUA 1LXMA 3KBTC 1N7RA 2XN0A 3DX1A 3M01A 5JMFA 3I3BA 5IK9A 1YQ2A 4AQ0A 1H14A 2A73B 3NBBA 3ON6A 3T08A 3EJSA 2V3NA 3G4DA 3ALAA 3OXUA 4AYQA 4AYPA 2XWJB 3BUQA 3K25A 3WA2X 4GTTB 4F10A 1D8DB 1FO2A 1GAIA 2VN7A 4JJJA 5JPMB 1N7PA 3G4FA 3D51A 3KN4A 5DHIA 1LURA 3M72A 2ZIRB 2JKEA 1O1SB 2ZQ0A 3AMOB 1H35A 2OQEA 5IKHA 3VSMA 3W7XA 2BB5A 3SAEA 3BS6A 1KKTA 4OJZA 1N95B 3W7WA 3S9VA 3HIGA 4KFDA 3PQIA 2ZXQA 5KBPA 3WIQA 3BUBA 2V8KA 3DX4A 3P5PA 1JZ6A 1HM3A 1RW9A 1LF6A 2F6DA 3RSYA 1NXCA 2WINB 2DRQA 1IQXA 1KRFA 2GOXA 1F4HA 2D73A 2YFNA 4OK2A 1S63B 3HXBB 1JZ3A 3WUXA 4WVBA 1PX3A 1QWNA 3Q78B 1CEMA 2KXSA 4YDOB 3SFYB 1NS0A 1TN8B 1TNYB 2AHFA 3QWTA 3PZ2B 3OBAA 2BRPA 2QNOA 2YFOA 3WFAA 1FBWA 4DLOA 2XHNA 3M02A 1RWFA 4D1IA 3LOYA 5FO8B 2JG0A 2Y74A 3N9HA 1AYXA 2VN4A 3QT9A 4ZG8A 3A24A 2EADA 3NREA 4EHMB 4C1SA 1LF9A 1F1SA 5DGQA 5ILYA 1HV6A 1RQ5A 1W3YA 1SA4B 3PYBA 3QG0A 1MMZA 2W0QA 2YIKA 3M77A 4EV5A 2WMIA 3E34B 2V8IA 2WW3A 4KTPA 4YCRA 3DX2A 1FCEA 4D6DA 3VD4A 4QT9A 4ZRQA 5GW7A 3HXEB 1JS4A 3MI6A 1IVVA 3E37B 3W5NA 2I07B 3M7LA 2WO0A 1N24A 2SQCA 4L6XA 3QT3A 1RJOA 3T0BA 1K1XA 4BTXA 3DECA 3CV5A 3KLSA 1NL4B 1FMIA 1F4AA 1MZCB 4DOEA 2WGQA 2WOFA 1N1ZA 1JRQA 1GAHA 3P5RA 2F1BA 3DX3A 4MMHA 4BZGA 1TQWA 2OW6A 1TN6B 1KSCA 4CJ0A 2FV1A 1NSXA 3QSPA 1RWGA 4GTSB 1N23A 2OW7A 4ZH1A 1QSJA 3A3VA 2WZSA 1UI7A 5E1QA 3RX8A 3DYMA 3KSLB 1JOVA 5EASA 2F7RA 1QAKA 1W6CA 2F7OA 5JPNB 4J5TA 1TQVA 1G6IA 3EZ8A 3P2CA 3TF4A 3IAQA 4V1RA 3X40A 2EACA 1PS3A 2AHGA 5A1AA 3TY1A 3DSVB 1K1YA 1NS2A 3RRSA 3QXQA 2E22A 4BZHA 3AFJA 5GZKA 1MMYA 2NVPA 5ILHA 3DCDA 1WMPA 1AGMA 3HXCB 1RWAA 5ILZA 1JZ5A 2WVXA 3ANIA
chains in the Genus database with same CATH topology
3MUZ1 1MMXA 4D6EA 4MMIA 1X1IA 1JZ2A 4OK4A 3K25A 3I3EA 4F10A 3VDAA 3OS7A 1JZ7A 1DP0A 1N7PA 2JKPA 4D6JA 1LURA 2HTBA 4F13A 2JKEA 3SEPA 3E1F1 2ZQ0A 1UG9A 3BGAA 4RNLA 1JZ8A 3VSMA 4FNVA 1J0MA 3BS6A 4OJZA 3T0AA 4TTGA 2WW0A 4D6HA 1NS7A 2ZXQA 3T2OA 1JYVA 1MMUA 1JZ6A 1HM3A 3IAPA 1RW9A 1LF6A 2FUQA 2D73A 1F4HA 1SNZA 4OK2A 1RWHA 1HMWA 1JZ3A 1N7QA 1NSRA 2BRVX 1OJOA 1PX3A 3Q1NA 3CZJA 5JMDA 4D6FA 1NS0A 3ECQA 1OJPA 3T09A 3OBAA 2BRPA 3IMHA 4DUXA 3WFAA 2WMHA 2XHNA 1RWFA 3T2PA 4D6GA 3DYPA 3NJXA 4BZFA 3A24A 3NREA 2WMIB 1SO0A 1NSMA 1HMUA 1LF9A 1F1SA 2FUTA 2WVZA 1MN0A 1HV6A 1W3YA 2WMJA 1PX4A 1NSZA 1EGUA 1HN0A 1MMZA 1LOHA 1HN1A 2WMIA 3I3DA 3VDCA 4BZEA 2E24A 2WW3A 1YGAA 4D6DA 3AFLA 3VD4A 3VDBA 4D6CA 1JZ4A 4OZVA 2CISA 1JYNA 1NKGA 1N7NA 3A0OA 1F9GA 2WMKA 1OJMA 3VD7A 3VSNA 2CIRA 3MV11 3BLCA 3VD9A 3T0BA 1K1XA 3DECA 4D6IA 2HTAA 3E7JA 1TXKA 2JKAA 2X03A 2WW2A 1NSSA 1Z45A 1F4AA 1CB8A 1HM2A 2CIQA 1I8QA 4MMHA 4BZGA 3MV01 3WVFA 2WVYA 2Q1FA 2WMGA 1N7OA 2WW1A 1NSUA 1JYXA 3NFVA 1NSXA 1RWGA 1ULVA 3MWXA 1NS8A 2WZSA 1NS4A 5E1QA 2WDAA 3DYMA 4D72A 1JOVA 3T0DA 3MUY1 2WMFA 3J7HA 4NEIA 1L7JA 3VD3A 1L7KA 4J5TA 3VD5A 1J0NA 1NSVA 4DUWA 3NNBA 3IAQA 3T2QA 1C82A 1OJNA 1QAZA 1RWCA 1K1WA 1X1HA 5A1AA 3TY1A 4D71A 1K1YA 1NS2A 4E1YA 2WVXB 1LXMA 4OZWA 1N7RA 3I3BA 2BRWA 2E22A 5JMFA 3OB8A 3E80A 4BZHA 1LXKA 1MMYA 1YQ2A 3NJVA 3DCDA 1JYWA 4AQ0A 3DYOA 1RWAA 1X1JA 3T08A 1JZ5A 4DUVA 2WVXA 2XSGA 2WCOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MUZ 1;  1MMX A;  4D6E A;  4MMI A;  1X1I A;  1JZ2 A;  4OK4 A;  3K25 A;  3I3E A;  4F10 A;  3VDA A;  3OS7 A;  1JZ7 A;  1DP0 A;  1N7P A;  2JKP A;  4D6J A;  1LUR A;  2HTB A;  4F13 A;  2JKE A;  3SEP A;  3E1F 1;  2ZQ0 A;  1UG9 A;  3BGA A;  4RNL A;  1JZ8 A;  3VSM A;  4FNV A;  1J0M A;  4OJZ A;  3T0A A;  4TTG A;  2WW0 A;  4D6H A;  1NS7 A;  2ZXQ A;  3T2O A;  1JYV A;  1MMU A;  1JZ6 A;  1HM3 A;  3IAP A;  1RW9 A;  1LF6 A;  2FUQ A;  2D73 A;  1F4H A;  1SNZ A;  4OK2 A;  1RWH A;  1HMW A;  1JZ3 A;  1N7Q A;  1NSR A;  2BRV X;  1OJO A;  1PX3 A;  3Q1N A;  3CZJ A;  5JMD A;  4D6F A;  1NS0 A;  3ECQ A;  1OJP A;  3T09 A;  3OBA A;  2BRP A;  3IMH A;  4DUX A;  3WFA A;  2WMH A;  2XHN A;  1RWF A;  3T2P A;  4D6G A;  3DYP A;  3NJX A;  4BZF A;  3A24 A;  3NRE A;  2WMI B;  1SO0 A;  1NSM A;  1HMU A;  1LF9 A;  1F1S A;  2FUT A;  2WVZ A;  1MN0 A;  1HV6 A;  1W3Y A;  2WMJ A;  1PX4 A;  1NSZ A;  1EGU A;  1HN0 A;  1MMZ A;  1LOH A;  1HN1 A;  2WMI A;  3I3D A;  3VDC A;  4BZE A;  2E24 A;  2WW3 A;  1YGA A;  4D6D A;  3AFL A;  3VD4 A;  3VDB A;  4D6C A;  1JZ4 A;  4OZV A;  2CIS A;  1JYN A;  1NKG A;  1N7N A;  3A0O A;  1F9G A;  2WMK A;  1OJM A;  3VD7 A;  3VSN A;  2CIR A;  3MV1 1;  3VD9 A;  3T0B A;  1K1X A;  3DEC A;  4D6I A;  2HTA A;  3E7J A;  1TXK A;  2JKA A;  2X03 A;  2WW2 A;  1NSS A;  1Z45 A;  1F4A A;  1CB8 A;  1HM2 A;  2CIQ A;  1I8Q A;  4MMH A;  4BZG A;  3MV0 1;  2WVY A;  2Q1F A;  2WMG A;  1N7O A;  2WW1 A;  1NSU A;  1JYX A;  3NFV A;  1NSX A;  1RWG A;  1ULV A;  3MWX A;  1NS8 A;  2WZS A;  1NS4 A;  5E1Q A;  2WDA A;  3DYM A;  4D72 A;  1JOV A;  3T0D A;  3MUY 1;  2WMF A;  3J7H A;  4NEI A;  1L7J A;  3VD3 A;  1L7K A;  3VD5 A;  4DUW A;  1J0N A;  1NSV A;  3NNB A;  3IAQ A;  3T2Q A;  1C82 A;  1OJN A;  1QAZ A;  1RWC A;  1K1W A;  1X1H A;  5A1A A;  4D71 A;  1K1Y A;  1NS2 A;  4E1Y A;  2WVX B;  1LXM A;  4OZW A;  1N7R A;  3I3B A;  2BRW A;  2E22 A;  5JMF A;  3OB8 A;  3E80 A;  4BZH A;  1LXK A;  1MMY A;  1YQ2 A;  3NJV A;  3DCD A;  1JYW A;  4AQ0 A;  3DYO A;  1RWA A;  1X1J A;  3T08 A;  1JZ5 A;  4DUV A;  2WVX A;  2XSG A;  2WCO A; 
#chains in the Genus database with same CATH topology
 2A8Z A;  3UD1 A;  3AMO A;  4D6E A;  1W4N A;  3ACS A;  1WU6 A;  2KXR A;  1TNB B;  4GL3 A;  2FYV A;  2C11 A;  4DOD A;  2R2L B;  4V1S A;  1HCU A;  2E2U A;  1NC5 A;  3Q7A B;  3OS7 A;  4K3A A;  1JZ7 A;  1DL2 A;  1N4R B;  2H6I B;  3RX7 A;  4D6J A;  3HXD B;  2HTB A;  2WY8 A;  4F13 A;  4MBG B;  1FT1 B;  1UG9 A;  4GTP B;  3WIR A;  1D6U A;  2CFK A;  3RX5 A;  3BGA A;  4FNR A;  4RNL A;  3PZ3 B;  3NBJ A;  3SDQ A;  1J0M A;  3SDV A;  3SDT A;  2OKX A;  3T0A A;  1KZP B;  3S4B A;  1H3A A;  3W5M A;  4D6H A;  2WW0 A;  3T2O A;  3E30 B;  1JYV A;  1HZF A;  3DDF A;  1WZZ A;  2G02 A;  3BVU A;  1F9O A;  2V3P A;  1F9D A;  1WU5 A;  2PN5 A;  1KSD A;  3D5R A;  2RDY A;  3Q73 B;  1HMW A;  1TNZ B;  1N7Q A;  3DSS B;  1NSR A;  3Q1N A;  1TQT A;  5CZL A;  1A2V A;  1O6R A;  3X3Y A;  3DPY B;  4GTV B;  4M76 A;  3ECQ A;  3T09 A;  4FXK B;  1GSZ A;  5IL3 A;  1O7D D;  3N0G A;  5IL8 A;  1QQF A;  1HXC A;  4D6G A;  1WMO A;  3DYP A;  2B39 A;  3ANJ A;  2NOJ A;  2WMI B;  2BBC A;  1HMU A;  1W6G A;  3BVW A;  2WVZ A;  1N4S B;  2ZZR A;  2IEJ B;  3PZ4 B;  1TU5 A;  4KKJ A;  1EGU A;  3U7V A;  3KII A;  1V7V A;  1QWU A;  3HXF B;  1VD5 A;  1YGA A;  3VDB A;  4OZV A;  1GXM A;  4L0G A;  2CIS A;  1UI8 A;  1NKG A;  3A0O A;  1F9G A;  1N94 B;  2PMV A;  4YDE B;  2OQE C;  4CE7 A;  2ZBL A;  1OJM A;  3K11 A;  1EKM A;  3VD7 A;  3VSN A;  3WKI A;  2CIR A;  3ANK A;  4XUV A;  3GZK A;  3SFX B;  3VD9 A;  4FXG B;  1AV4 A;  5IKA A;  3QPF A;  2WW2 A;  2X03 A;  4AYR A;  3X42 A;  2F0Y B;  3Q75 B;  1WMN A;  1H3C A;  1Z45 A;  2F1A A;  3M76 A;  1JCQ B;  1QAL A;  4BOJ A;  1HM2 A;  4ZH5 A;  1V5C A;  3G6J B;  2WYH A;  3REN A;  1D6Z A;  4D4A A;  1QAF A;  3WVF A;  2Q1F A;  1X81 B;  1N7O A;  1TF4 A;  2J5C A;  2WW1 A;  2WOH A;  1UMP A;  3VW5 A;  1ULV A;  2H6F B;  3MWX A;  1X9D A;  5ILD A;  2EAE A;  1N1B A;  2WDA A;  3J7H A;  2CWT A;  1TQS A;  3D4Z A;  1O6Q A;  1N4P B;  4BTW A;  1IVW A;  1NSV A;  3WIW A;  1HXK A;  1C82 A;  4EL8 A;  2CWV A;  4BTY A;  1IA7 A;  3E73 A;  2GZ6 A;  1N9E A;  2WVX B;  5ILK A;  5M7I A;  1N4Q B;  3X3X A;  2BRW A;  1SA5 B;  3S4A A;  4KFF A;  1TNO B;  1LXK A;  5FO9 B;  5IM1 A;  3NJV A;  4TXT A;  2BED B;  3DYO A;  5AGD A;  1X1J A;  2GH4 A;  3Q7F B;  1QX1 A;  4DUV A;  2WCO A;  1MMX A;  4MMI A;  3E32 B;  3QFZ A;  1X1I A;  2E2T A;  1L1Y A;  4D8O A;  1JZ2 A;  4DI5 A;  3I3E A;  3VDA A;  1XWT A;  3WA3 A;  5FOB B;  1IVX A;  3WKF A;  3QRY A;  3E1F 1;  3SEP A;  1N20 A;  2DRS A;  3LZ9 A;  1H3B A;  2OOV A;  1LD8 B;  4GTM B;  1FAE A;  2P0V A;  3BVT A;  4KTR A;  1GHQ A;  1K72 A;  4Z4L A;  1IA6 A;  2XN2 A;  4EV2 A;  1HXG A;  2XQW A;  4FNU A;  4LIX A;  3IAP A;  4Z4J A;  2FUQ A;  4GAX A;  2PNC A;  5IK0 A;  1SNZ A;  5C05 A;  4ZRP A;  3W7U A;  1RWH A;  1PU4 A;  2Z07 A;  2CG1 A;  1KS8 A;  1OJO A;  3H3K A;  5JMD A;  4D6F A;  1OJP A;  4FNS A;  2CG0 A;  3C72 B;  3GT5 A;  5FO7 B;  1DCE B;  1H54 A;  4GTO B;  1LD7 B;  3Q79 B;  1R33 A;  1FPP B;  2YX9 A;  3M7C A;  3T2P A;  3NJX A;  3DST B;  1JCS B;  3X17 A;  1N21 A;  3BLB A;  2OOV C;  1R34 A;  1SO0 A;  1NSM A;  1HX9 A;  3W7S A;  3D52 A;  3EU5 B;  1FO3 A;  1N9A B;  2FUT A;  2WMJ A;  2RI8 A;  5ILJ A;  4FJQ A;  3BUD A;  4WU0 A;  2D5J A;  2E24 A;  1O6H A;  3AFL A;  4D6C A;  1OAC A;  2V8J A;  1JZ4 A;  2WII B;  3BVV A;  1W7C A;  3SQC A;  5ILI A;  2XWB B;  1JYN A;  1N7N A;  3EU8 A;  3KSQ B;  2F7P A;  2WYN A;  2ZIS B;  3KQ4 A;  1H13 A;  3M7B A;  1SPU A;  1G9G A;  2BT3 A;  1W2Z A;  3KBU C;  1S64 B;  4CJ1 A;  3BLC A;  1HXA A;  3PYA A;  1HWW A;  5CD2 A;  4AYO A;  5IK6 A;  1D8E B;  1KSI A;  1NSS A;  2H6H B;  3DSU B;  5EAT A;  3CZN A;  3T0U A;  3PZ1 B;  2CIQ A;  2JJB A;  3CZS A;  1O1T B;  1I8Q A;  3SXX A;  3MV0 1;  2WMG A;  1H39 A;  1NSU A;  1JYX A;  3NFV A;  3BUI A;  1O5M B;  1NS8 A;  3BVX A;  3DSW B;  1NS4 A;  3X3Z A;  2CFL A;  4D72 A;  3D4Y A;  3MUY 1;  3PMM A;  1D6Y A;  1L7J A;  3WKH A;  4K35 A;  1GXO A;  3QDE A;  4D4B A;  1L7K A;  1C3D A;  3VD5 A;  4DUW A;  5DGR A;  3F59 A;  3E33 B;  1OJN A;  1RWC A;  1K1W A;  3PGB A;  4ONT A;  4D71 A;  1WU4 A;  4E1Y A;  4LNV A;  4KFE A;  1H12 A;  4OZW A;  5DHK A;  1O79 A;  2G0D A;  3SDU A;  4FNP A;  1G87 A;  3E80 A;  3OB8 A;  2RI9 A;  1US1 A;  1DOG A;  2B4F A;  1L2A A;  1JYW A;  5MEH A;  4WVC A;  2CWU A;  4FUS A;  2WY7 A;  1W6K A;  2XSG A;  1QBQ B;  5CA3 A;  4D4C A;  3MUZ 1;  2DRR A;  3S4C A;  3EJR A;  4OK4 A;  4RNQ A;  1KFG A;  2ONH A;  1W5Z A;  2F7Q A;  1UT9 A;  3WC3 A;  3EJQ A;  1H36 A;  4FNT A;  2E2V A;  3DDG A;  3W7T A;  1DP0 A;  2JKP A;  3X41 A;  2CFW A;  3M71 A;  4MU9 A;  1V5D A;  4KKI A;  1JZ8 A;  3N0F A;  2EAB A;  1TQU A;  4FNV A;  1R76 A;  3GLY A;  4TTG A;  3LVT A;  1NS7 A;  1JCR B;  1FBO A;  3MPH A;  1LTX B;  1MMU A;  1HTY A;  3EJT A;  1GLM A;  4Q88 A;  4DLQ A;  2F18 A;  2BRV X;  2AFA A;  3M7E A;  3CZJ A;  3H2W A;  3K7X A;  1IVU A;  2Y73 A;  3EJP A;  3M78 A;  5E2J A;  1FP3 A;  3BUP A;  3IMH A;  4DUX A;  1KZO B;  4Q2B A;  5EAU A;  2WMH A;  1SIH A;  4WVA A;  3M73 A;  2CFD A;  1GXN A;  3DSX B;  3M75 A;  4BZF A;  4LNG B;  3EQA A;  3RJ3 A;  3SDR A;  3M00 A;  1AVL A;  2ALW A;  4LNB B;  5M7Y A;  2CFG A;  3EJU A;  1LVN A;  2C10 A;  1O1R B;  5KKB A;  1KRE A;  1RKY A;  1SQC A;  1MN0 A;  1PX4 A;  1NSZ A;  3WKG A;  1HN0 A;  1LOH A;  2D8L A;  5GY3 A;  1IU7 A;  1HN1 A;  3EUV B;  3I3D A;  3VDC A;  3CU7 A;  4BZE A;  1V7X A;  1XWQ A;  3S4D A;  1V7W A;  3HII A;  4D94 A;  4GTQ B;  1XW2 A;  2WMK A;  1FT2 B;  3UD2 A;  2FV0 A;  2ONG A;  1N22 A;  3DX0 A;  3MV1 1;  3D50 A;  4D1J A;  3D3I A;  4TF4 A;  4D4D A;  4D6I A;  1SII A;  2HTA A;  3E7J A;  3QFY A;  4L9P B;  1TXK A;  2JKA A;  1IQY A;  2H6G B;  2RGK A;  2FBA A;  1W6J A;  1G9J A;  3HI7 A;  3SX1 A;  1CB8 A;  3DRA B;  2ZL8 A;  4UFC A;  1GA2 A;  1TN7 B;  3H7L A;  2WVY A;  1AVK A;  3QXF A;  2D1W A;  1IS9 A;  1NI1 B;  3OED A;  3QR8 A;  3D5S A;  3CIH A;  4GTR B;  3VXD A;  1CLC A;  3T0D A;  2WMF A;  2CQT A;  3ACT A;  4NEI A;  3M74 A;  3VD3 A;  2DRO A;  2FUZ A;  3T33 A;  1J0N A;  3E6U A;  2BB6 A;  2XN1 A;  3NNB A;  3T2Q A;  2CQS A;  2JF4 A;  1TNU B;  4FNQ A;  1QAZ A;  1KWF A;  1X1H A;  2WYI A;  3K5T A;  1H37 A;  2XFG A;  4BOK A;  1DYU A;  1LXM A;  3KBT C;  1N7R A;  2XN0 A;  3DX1 A;  3M01 A;  5JMF A;  3I3B A;  5IK9 A;  1YQ2 A;  4AQ0 A;  1H14 A;  2A73 B;  3NBB A;  3ON6 A;  3T08 A;  3EJS A;  2V3N A;  3G4D A;  3ALA A;  3OXU A;  4AYQ A;  4AYP A;  2XWJ B;  3BUQ A;  3K25 A;  3WA2 X;  4GTT B;  4F10 A;  1D8D B;  1FO2 A;  1GAI A;  2VN7 A;  4JJJ A;  5JPM B;  1N7P A;  3G4F A;  3D51 A;  3KN4 A;  5DHI A;  1LUR A;  3M72 A;  2ZIR B;  2JKE A;  1O1S B;  2ZQ0 A;  3AMO B;  1H35 A;  2OQE A;  5IKH A;  3VSM A;  3W7X A;  2BB5 A;  3SAE A;  3BS6 A;  1KKT A;  4OJZ A;  1N95 B;  3W7W A;  3S9V A;  3HIG A;  4KFD A;  3PQI A;  2ZXQ A;  5KBP A;  3WIQ A;  3BUB A;  2V8K A;  3DX4 A;  3P5P A;  1JZ6 A;  1HM3 A;  1RW9 A;  1LF6 A;  2F6D A;  3RSY A;  1NXC A;  2WIN B;  2DRQ A;  1IQX A;  1KRF A;  2GOX A;  1F4H A;  2D73 A;  2YFN A;  4OK2 A;  1S63 B;  3HXB B;  1JZ3 A;  3WUX A;  4WVB A;  1PX3 A;  1QWN A;  3Q78 B;  1CEM A;  2KXS A;  4YDO B;  3SFY B;  1NS0 A;  1TN8 B;  1TNY B;  2AHF A;  3QWT A;  3PZ2 B;  3OBA A;  2BRP A;  2QNO A;  2YFO A;  3WFA A;  1FBW A;  4DLO A;  2XHN A;  3M02 A;  1RWF A;  4D1I A;  3LOY A;  5FO8 B;  2JG0 A;  2Y74 A;  3N9H A;  1AYX A;  2VN4 A;  3QT9 A;  4ZG8 A;  3A24 A;  2EAD A;  3NRE A;  4EHM B;  4C1S A;  1LF9 A;  1F1S A;  5DGQ A;  5ILY A;  1HV6 A;  1RQ5 A;  1W3Y A;  1SA4 B;  3PYB A;  3QG0 A;  1MMZ A;  2W0Q A;  2YIK A;  3M77 A;  4EV5 A;  2WMI A;  3E34 B;  2V8I A;  2WW3 A;  4KTP A;  4YCR A;  3DX2 A;  1FCE A;  4D6D A;  3VD4 A;  4QT9 A;  4ZRQ A;  5GW7 A;  3HXE B;  1JS4 A;  3MI6 A;  1IVV A;  3E37 B;  3W5N A;  2I07 B;  3M7L A;  2WO0 A;  1N24 A;  2SQC A;  4L6X A;  3QT3 A;  1RJO A;  3T0B A;  1K1X A;  4BTX A;  3DEC A;  3CV5 A;  3KLS A;  1NL4 B;  1FMI A;  1F4A A;  1MZC B;  4DOE A;  2WGQ A;  2WOF A;  1N1Z A;  1JRQ A;  1GAH A;  3P5R A;  2F1B A;  3DX3 A;  4MMH A;  4BZG A;  1TQW A;  2OW6 A;  1TN6 B;  1KSC A;  4CJ0 A;  2FV1 A;  1NSX A;  3QSP A;  1RWG A;  4GTS B;  1N23 A;  2OW7 A;  4ZH1 A;  1QSJ A;  3A3V A;  2WZS A;  1UI7 A;  5E1Q A;  3RX8 A;  3DYM A;  3KSL B;  1JOV A;  5EAS A;  2F7R A;  1QAK A;  1W6C A;  2F7O A;  5JPN B;  4J5T A;  1TQV A;  1G6I A;  3EZ8 A;  3P2C A;  3TF4 A;  3IAQ A;  4V1R A;  3X40 A;  2EAC A;  1PS3 A;  2AHG A;  5A1A A;  3TY1 A;  3DSV B;  1K1Y A;  1NS2 A;  3RRS A;  3QXQ A;  2E22 A;  4BZH A;  3AFJ A;  5GZK A;  1MMY A;  2NVP A;  5ILH A;  3DCD A;  1WMP A;  1AGM A;  3HXC B;  1RWA A;  5ILZ A;  1JZ5 A;  2WVX A;  3ANI A; 
#chains in the Genus database with same CATH homology
 3MUZ 1;  1MMX A;  4D6E A;  4MMI A;  1X1I A;  1JZ2 A;  4OK4 A;  3K25 A;  3I3E A;  4F10 A;  3VDA A;  3OS7 A;  1JZ7 A;  1DP0 A;  1N7P A;  2JKP A;  4D6J A;  1LUR A;  2HTB A;  4F13 A;  2JKE A;  3SEP A;  3E1F 1;  2ZQ0 A;  1UG9 A;  3BGA A;  4RNL A;  1JZ8 A;  3VSM A;  4FNV A;  1J0M A;  3BS6 A;  4OJZ A;  3T0A A;  4TTG A;  2WW0 A;  4D6H A;  1NS7 A;  2ZXQ A;  3T2O A;  1JYV A;  1MMU A;  1JZ6 A;  1HM3 A;  3IAP A;  1RW9 A;  1LF6 A;  2FUQ A;  2D73 A;  1F4H A;  1SNZ A;  4OK2 A;  1RWH A;  1HMW A;  1JZ3 A;  1N7Q A;  1NSR A;  2BRV X;  1OJO A;  1PX3 A;  3Q1N A;  3CZJ A;  5JMD A;  4D6F A;  1NS0 A;  3ECQ A;  1OJP A;  3T09 A;  3OBA A;  2BRP A;  3IMH A;  4DUX A;  3WFA A;  2WMH A;  2XHN A;  1RWF A;  3T2P A;  4D6G A;  3DYP A;  3NJX A;  4BZF A;  3A24 A;  3NRE A;  2WMI B;  1SO0 A;  1NSM A;  1HMU A;  1LF9 A;  1F1S A;  2FUT A;  2WVZ A;  1MN0 A;  1HV6 A;  1W3Y A;  2WMJ A;  1PX4 A;  1NSZ A;  1EGU A;  1HN0 A;  1MMZ A;  1LOH A;  1HN1 A;  2WMI A;  3I3D A;  3VDC A;  4BZE A;  2E24 A;  2WW3 A;  1YGA A;  4D6D A;  3AFL A;  3VD4 A;  3VDB A;  4D6C A;  1JZ4 A;  4OZV A;  2CIS A;  1JYN A;  1NKG A;  1N7N A;  3A0O A;  1F9G A;  2WMK A;  1OJM A;  3VD7 A;  3VSN A;  2CIR A;  3MV1 1;  3BLC A;  3VD9 A;  3T0B A;  1K1X A;  3DEC A;  4D6I A;  2HTA A;  3E7J A;  1TXK A;  2JKA A;  2X03 A;  2WW2 A;  1NSS A;  1Z45 A;  1F4A A;  1CB8 A;  1HM2 A;  2CIQ A;  1I8Q A;  4MMH A;  4BZG A;  3MV0 1;  3WVF A;  2WVY A;  2Q1F A;  2WMG A;  1N7O A;  2WW1 A;  1NSU A;  1JYX A;  3NFV A;  1NSX A;  1RWG A;  1ULV A;  3MWX A;  1NS8 A;  2WZS A;  1NS4 A;  5E1Q A;  2WDA A;  3DYM A;  4D72 A;  1JOV A;  3T0D A;  3MUY 1;  2WMF A;  3J7H A;  4NEI A;  1L7J A;  3VD3 A;  1L7K A;  4J5T A;  3VD5 A;  1J0N A;  1NSV A;  4DUW A;  3NNB A;  3IAQ A;  3T2Q A;  1C82 A;  1OJN A;  1QAZ A;  1RWC A;  1K1W A;  1X1H A;  5A1A A;  3TY1 A;  4D71 A;  1K1Y A;  1NS2 A;  4E1Y A;  2WVX B;  1LXM A;  4OZW A;  1N7R A;  3I3B A;  2BRW A;  2E22 A;  5JMF A;  3OB8 A;  3E80 A;  4BZH A;  1LXK A;  1MMY A;  1YQ2 A;  3NJV A;  3DCD A;  1JYW A;  4AQ0 A;  3DYO A;  1RWA A;  1X1J A;  3T08 A;  1JZ5 A;  4DUV A;  2WVX A;  2XSG A;  2WCO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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