2WDAA

The x-ray structure of the streptomyces coelicolor a3 chondroitin ac lyase in complex with chondroitin sulphate
Total Genus 261
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces violaceoruber
molecule tags Lyase
molecule keywords PUTATIVE SECRETED LYASE
total genus 261
structure length 742
sequence length 742
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2wdaA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2wdaA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2wdaA02
4D6EA 1N7QA 1JZ6A 4OZWA 3MUY1 3MV11 3VD7A 3NJVA 2ZXQA 3J7HA 1N7RA 1RWGA 1NSSA 3OB8A 4E1YA 3NFVA 1TXKA 3A24A 1DP0A 5JMFA 1NS7A 1QAZA 1LF6A 3IAPA 1HV6A 4MMHA 1UG9A 3T0AA 2WCOA 4D72A 3T2QA 1F1SA 3VSNA 2WMFA 1MMZA 2WW1A 1YQ2A 2WVYA 2WMKA 1NSMA 3DYPA 4AQ0A 1HM3A 2WW0A 1JZ3A 3VD4A 1L7KA 1NS0A 1RWCA 2BRVX 1NSRA 3E7JA 1RW9A 2FUQA 4D6IA 1RWHA 1LF9A 4RNLA 3MV01 4BZFA 3VD9A 2WVZA 3AFLA 1MN0A 1NS2A 4D71A 1NS8A 3DECA 3T2OA 3MUZ1 1LURA 1SO0A 2CIRA 2WMHA 3MWXA 1C82A 3E80A 3A0OA 3OS7A 1JZ2A 1MMXA 4D6FA 1F4AA 3T0BA 1N7NA 3VD3A 2JKEA 4D6JA 2WZSA 3ECQA 1EGUA 4OK4A 4NEIA 1RWFA 4F10A 3Q1NA 4BZEA 4D6DA 3SEPA 1JYVA 3I3EA 1JYWA 1NS4A 4BZGA 3K25A 1N7PA 2BRPA 1LXKA 2XHNA 3VDBA 1K1XA 2HTAA 1LOHA 2ZQ0A 3CZJA 1HMUA 4D6HA 1F4HA 5E1QA 1X1HA 4TTGA 1OJOA 1X1IA 5A1AA 1OJMA 3VSMA 4F13A 1J0NA 2JKPA 1NKGA 2JKAA 1MMYA 1L7JA 2WMGA 1JZ5A 1JZ8A 3T2PA 1HN0A 3T08A 1MMUA 2E22A 4DUXA 1SNZA 4MMIA 3VDCA 1YGAA 2WVXA 1X1JA 1JZ7A 2BRWA 4FNVA 1OJNA 3VDAA 4OZVA 3IAQA 2WVXB 4OJZA 2CISA 1NSXA 1RWAA 1CB8A 1F9GA 2E24A 1NSUA 3BGAA 2WMJA 3NNBA 2WMIB 1W3YA 1I8QA 1K1WA 3VD5A 2Q1FA 2X03A 3E1F1 3IMHA 3NJXA 3DYMA 4BZHA 1PX3A 1J0MA 2WDAA 1K1YA 1NSZA 3DCDA 4DUWA 4DUVA 1JZ4A 1JYNA 1LXMA 1PX4A 5JMDA 3T09A 2HTBA 3OBAA 1JOVA 1ULVA 1NSVA 1N7OA 1OJPA 2XSGA 1HN1A 2FUTA 2WW3A 2WW2A 4D6GA 3DYOA 2WMIA 1Z45A 4OK2A 3I3DA 4D6CA 2D73A 3NREA 3T0DA 1HM2A 2CIQA 3WFAA 1HMWA 3I3BA 1JYXA
chains in the Genus database with same CATH superfamily
4D6EA 1N7QA 3P5PA 2E2UA 4OZWA 4GTMB 3DYPA 3MUY1 1KSCA 1N4PB 3NJVA 4BOJA 1TQWA 2ZXQA 1HXGA 3J7HA 3DSXB 5CA3A 1TNYB 3VW5A 3ANKA 3OB8A 2H6GB 4E1YA 2JG0A 3X40A 2CWTA 4DLOA 5IKAA 1S63B 3K7XA 1FMIA 4AQ0A 1SPUA 5ILZA 3KSLB 3H2WA 4ZH5A 1NS7A 4ZH1A 3LOYA 4CJ1A 2G02A 3S9VA 3T0UA 2ONGA 1LF6A 3HXDB 3IAPA 1N94B 5IL3A 3PZ2B 5MEHA 2FUZA 3TY1A 1V7WA 3VD4A 2WW0A 3BVUA 1KS8A 2CFDA 4TF4A 3N0GA 1RW9A 3W7WA 1MN0A 4D71A 3MUZ1 3QXFA 1K72A 3PMMA 2Z07A 1MZCB 2WMHA 1C82A 2J5CA 3MI6A 4BTWA 3A0OA 2WO0A 2E2TA 2CG0A 2P0VA 1WMPA 4D6FA 1F4AA 3T0BA 3D52A 4D6JA 4YCRA 4F10A 3DDGA 4D6DA 3I3EA 3SDQA 3M71A 4BTYA 4K35A 1TQUA 4GTQB 1UMPA 3E73A 3S4CA 1N7PA 2BRPA 2DROA 2OW6A 3TF4A 2HTAA 4FNTA 2XWJB 1TN6B 3AMOA 4AYPA 4LIXA 1QX1A 1IA6A 2A73B 1FAEA 3AMOB 1IS9A 3X3XA 5A1AA 1OJMA 3M7LA 1NL4B 3W5MA 3BVVA 2QNOA 2XQWA 3M7BA 1PU4A 1SA4B 2H6IB 1HN0A 2WYNA 3T08A 2E22A 2F7PA 3WKIA 3P2CA 2D5JA 4BOKA 2CIQA 3SQCA 1IVWA 4OZVA 3IAQA 1N22A 3H7LA 2EAEA 2RI9A 3GT5A 3X3ZA 2AFAA 2JJBA 4KKJA 1RWAA 2E24A 3CV5A 1C3DA 3HXCB 5FO7B 2DRQA 4AYOA 3X41A 1W4NA 3SXXA 1FBOA 1O1SB 1O6HA 1X81B 1SIIA 3VD5A 4FNUA 3E1F1 1H37A 3NJXA 4BZHA 1JCSB 2KXSA 3DSTB 1K1YA 1NSZA 5DGQA 3E32B 4GTTB 4XUVA 3QPFA 4Z4LA 3W7XA 1PX4A 1JYNA 5JMDA 2CQSA 4GTPB 3U7VA 1RKYA 1N1ZA 1KWFA 2DRRA 1NSVA 1LTXB 1XW2A 2ZIRB 3CU7A 4LNVA 3ACSA 2AHFA 4D6GA 4K3AA 4MU9A 2FBAA 2WMIA 4FUSA 3I3DA 2F6DA 3M7CA 4KFEA 1DL2A 1HM2A 1FT1B 2H6FB 4LNBB 5IK9A 3WFAA 3E33B 1AVKA 5KKBA 1KREA 1DCEB 1IA7A 3Q7FB 3PQIA 1NSSA 3WA3A 1JRQA 3N0FA 1TXKA 1SIHA 2GOXA 2OOVC 4DOEA 2OQEC 3M77A 2PN5A 3A24A 5JMFA 1SA5B 2CFLA 1GAIA 4FXGB 3G4DA 4FXKB 3EJRA 1HTYA 1UG9A 4GAXA 3HI7A 4Q88A 2YIKA 4D72A 1GXMA 2WGQA 2F0YB 3VSNA 1GSZA 2WMFA 3EQAA 3QDEA 1MMZA 1O79A 1N4RB 2V3NA 3KSQB 2WMKA 1NSMA 4D4AA 2E2VA 4KTPA 3SDUA 2RGKA 3QFZA 1L7KA 1NS0A 2F7RA 3E7JA 4BZFA 3VD9A 1VD5A 2WY7A 3MV01 2OQEA 5ILJA 3HXFB 3Q79B 1V5DA 1W7CA 1TNUB 1WZZA 1LD8B 5FOBB 3MWXA 4M76A 1H14A 1JS4A 5IM1A 3DX0A 3KQ4A 1H36A 3WUXA 1MMXA 1UI7A 1GXOA 1D6YA 3QT9A 2JKEA 2WZSA 3SAEA 1EGUA 3RX5A 3DDFA 4KFFA 4NEIA 3PYAA 2IEJB 3D4ZA 4FNRA 3WIRA 2BB6A 5ILHA 1JCRB 3E37B 3D50A 4BZGA 2YFOA 1LXKA 2XHNA 1N4SB 3K11A 3M7EA 1K1XA 2ZQ0A 3CZJA 3DRAB 4D6HA 1F4HA 5DHKA 5M7YA 1W6JA 3M01A 4ZRPA 2BB5A 1X1HA 3WVFA 4MBGB 1O1TB 3PGBA 5GW7A 3BS6A 3RSYA 1H35A 1H12A 2JKPA 3BVXA 4YDOB 3SFYB 3QR8A 1MMYA 2WMGA 3QT3A 2JKAA 1OACA 1JZ5A 1JZ8A 3T2PA 1QAKA 2V8IA 3WC3A 3QSPA 1N4QB 1AVLA 3DX1A 4CE7A 4J5TA 5CD2A 1UI8A 2D8LA 1X1JA 3BUIA 1G9GA 1JZ7A 3KIIA 1OJNA 5C05A 1W5ZA 5FO8B 1GA2A 4OJZA 2CISA 2C10A 3WKGA 1IVVA 3E34B 2AHGA 4EL8A 3BGAA 3DX3A 3M02A 4QT9A 3NNBA 1W3YA 2H6HB 4GTOB 1CEMA 1DOGA 2CFWA 2D1WA 1WMNA 1D8DB 2XN1A 1R33A 3DYMA 4GTVB 1PX3A 1J0MA 1D6UA 1O6RA 1RQ5A 1LXMA 3SFXB 1QAFA 2CFGA 2ZBLA 3OBAA 1ULVA 2G0DA 1AYXA 1FPPB 1OJPA 2WYIA 1G9JA 3HXEB 3T0DA 1AGMA 4AYQA 2XFGA 3W7TA 1IQYA 1HMWA 1FT2B 1L2AA 3BUBA 1JZ6A 1LD7B 4ZRQA 2OKXA 4D1JA 2F1AA 3M76A 2FYVA 1O7DD 4KFDA 1V7VA 2SQCA 2CWUA 1RWGA 2I07B 3PZ1B 4TXTA 3EJPA 2GH4A 2C11A 3NFVA 1W6CA 4D4DA 5IKHA 1PS3A 3QXQA 5ILYA 4D1IA 3X3YA 4KTRA 4V1RA 1FO2A 2YX9A 4LNGB 1HV6A 4MMHA 1RJOA 5DHIA 3CZNA 1TQTA 2WCOA 3EU8A 2WY8A 3EJSA 3EJQA 1UT9A 3X17A 1YQ2A 2WVYA 2CG1A 1JZ3A 3P5RA 4GTRB 2F18A 4EHMB 1RWCA 2BRVX 1TNOB 1FO3A 1NSRA 4D6IA 1RWHA 4RNLA 2WVZA 3AFLA 5JPMB 1N9EA 1NS2A 1N9AB 1N1BA 1V5CA 1LURA 1HXCA 1SO0A 3M74A 1L1YA 3M72A 5GY3A 3BLBA 3OS7A 2CQTA 2F7QA 1KSIA 4CJ0A 3VD3A 1N7NA 5FO9B 1DYUA 1QWNA 1TQSA 1KZPB 1KSDA 3NBJA 4OK4A 1RWFA 1TNZB 3UD2A 2WOHA 1GXNA 4BZEA 3M78A 2KXRA 3ALAA 3SEPA 3ANIA 3QRYA 4WVBA 1JYVA 1JYWA 1WU4A 5IL8A 5ILDA 1JCQB 1R76A 3K25A 3M75A 1IVXA 1WU6A 3BUPA 3VDBA 2XN2A 1LOHA 3G4FA 1GHQA 2PMVA 1HMUA 2R2LB 3KLSA 3SX1A 1XWQA 3HXBB 3SDTA 1GAHA 1G6IA 5CZLA 3WKFA 4TTGA 1X1IA 3G6JB 3DSWB 2ZL8A 3RENA 3VSMA 4F13A 1QBQB 1L7JA 1V7XA 1W6KA 4DUXA 1SNZA 1TN8B 3VDCA 1YGAA 2BT3A 2CFKA 2WVXA 1H3CA 3CIHA 1HX9A 2XN0A 2ZZRA 4FNVA 3WKHA 1WMOA 1TNBB 3S4BA 3CZSA 1R34A 1F9GA 4WU0A 1N95B 2EABA 3PYBA 3E30B 3BLCA 2WMJA 2WMIB 2VN4A 3RJ3A 3DSVB 3EZ8A 1H3BA 3ANJA 4FNSA 1K1WA 2RDYA 3OEDA 3LVTA 1QQFA 1F9OA 3M00A 2WYHA 3DX2A 4BTXA 2FV0A 3IMHA 3MPHA 3W7SA 1H3AA 4AYRA 2WDAA 3EUVB 2GZ6A 2DRSA 5IK6A 3DX4A 5KBPA 1H13A 4L0GA 1US1A 3T09A 2XWBB 3NBBA 1HWWA 1FCEA 4D4CA 2FUTA 3RX8A 4L6XA 3KBUC 3EU5B 5DGRA 1KZOB 2WW2A 1QALA 2V8KA 4OK2A 3T33A 4D6CA 2D73A 3ON6A 3RX7A 1KFGA 3N9HA 3I3BA 1JYXA 3D3IA 5EASA 2W0QA 5EATA 3QG0A 3MV11 3D4YA 1FBWA 2A8ZA 3VD7A 3LZ9A 4FJQA 3PZ3B 3UD1A 3K5TA 3D5RA 1FP3A 1N7RA 3SDRA 1NI1B 3DSUB 4WVCA 4EV2A 3OXUA 1A2VA 1IQXA 1CLCA 1O5MB 1QWUA 3WIQA 4FNQA 3WIWA 3KBTC 1HXKA 3Q75B 1DP0A 3AFJA 4C1SA 4Q2BA 4D8OA 1N21A 1QAZA 2NVPA 5IK0A 2F1BA 3T0AA 1IVUA 1H54A 2F7OA 3T2QA 1F1SA 2WW1A 2BBCA 1HM3A 2NOJA 3GLYA 1LF9A 2FUQA 1GLMA 1TN7B 1S64B 2EACA 3T2OA 4WVAA 1NS8A 3DECA 4KKIA 3QFYA 4DODA 2CIRA 3E80A 3EJTA 1F9DA 2ONHA 2Y74A 1JZ2A 1TF4A 1WU5A 2JF4A 3RRSA 3ECQA 1O1RB 2B39A 3BVTA 4V1SA 3Q1NA 3E6UA 4GL3A 1O6QA 3SDVA 1N24A 3PZ4B 1N23A 1NS4A 1HCUA 3BUQA 5GZKA 4DLQA 2OOVA 4UFCA 3C72B 2ZISB 1NXCA 3Q73B 4ONTA 3KN4A 1KKTA 3D5SA 1W6GA 3X42A 3F59A 5E1QA 4EV5A 2ALWA 1OJOA 3GZKA 3M73A 4JJJA 2WINB 5E2JA 5EAUA 1W2ZA 3S4DA 1J0NA 4L9PB 1NKGA 1G87A 1AV4A 2RI8A 1TQVA 3BUDA 5M7IA 3WA2X 1MMUA 4D94A 3ACTA 2VN7A 4MMIA 1TU5A 2B4FA 3HIGA 2WIIB 2BRWA 4Z4JA 3Q78B 2BEDB 3VXDA 3D51A 3VDAA 5ILKA 4ZG8A 1KRFA 2WVXB 1IU7A 4DI5A 3DPYB 1SQCA 1D6ZA 1NSXA 1CB8A 3W7UA 1NSUA 3BVWA 3HIIA 1I8QA 3S4AA 1HXAA 2PNCA 3H3KA 2Q1FA 1QSJA 2X03A 5AGDA 2WOFA 4FNPA 1N20A 1EKMA 1HZFA 3DCDA 4DUWA 4DUVA 4D4BA 2EADA 2CWVA 1XWTA 1LVNA 2FV1A 1JZ4A 5ILIA 1H39A 3A3VA 3QWTA 1D8EB 2HTBA 2V8JA 1JOVA 2Y73A 1N7OA 5JPNB 2XSGA 1HN1A 2WW3A 3Q7AB 2OW7A 4RNQA 3DYOA 2V3PA 4YDEB 1NC5A 1Z45A 2YFNA 3NREA 3EJUA 1X9DA 3DSSB 3W5NA 4GTSB
chains in the Genus database with same CATH topology
4D6EA 1N7QA 1JZ6A 4OZWA 3MUY1 3MV11 3VD7A 3NJVA 2ZXQA 3J7HA 1N7RA 1RWGA 1NSSA 3OB8A 4E1YA 3NFVA 1TXKA 3A24A 1DP0A 5JMFA 1NS7A 1QAZA 1LF6A 3IAPA 1HV6A 4MMHA 1UG9A 3T0AA 2WCOA 4D72A 3T2QA 3TY1A 1F1SA 3VSNA 2WMFA 1MMZA 2WW1A 1YQ2A 2WVYA 2WMKA 1NSMA 3DYPA 4AQ0A 1HM3A 2WW0A 1JZ3A 3VD4A 1L7KA 1NS0A 1RWCA 2BRVX 1NSRA 3E7JA 1RW9A 2FUQA 4D6IA 1RWHA 1LF9A 4RNLA 3MV01 4BZFA 3VD9A 2WVZA 3AFLA 1MN0A 1NS2A 4D71A 1NS8A 3DECA 3T2OA 3MUZ1 1LURA 1SO0A 2CIRA 2WMHA 3MWXA 1C82A 3E80A 3A0OA 3OS7A 1JZ2A 1MMXA 4D6FA 1F4AA 3T0BA 1N7NA 3VD3A 2JKEA 4D6JA 2WZSA 3ECQA 1EGUA 4OK4A 4NEIA 1RWFA 4F10A 3Q1NA 4BZEA 4D6DA 3SEPA 1JYVA 3I3EA 1JYWA 1NS4A 4BZGA 3K25A 1N7PA 2BRPA 1LXKA 2XHNA 3VDBA 1K1XA 2HTAA 1LOHA 2ZQ0A 3CZJA 1HMUA 4D6HA 1F4HA 5E1QA 3WVFA 1X1HA 4TTGA 1OJOA 1X1IA 3BS6A 5A1AA 1OJMA 3VSMA 4F13A 1J0NA 2JKPA 1NKGA 2JKAA 1MMYA 1L7JA 2WMGA 1JZ5A 1JZ8A 3T2PA 1HN0A 3T08A 1MMUA 2E22A 4DUXA 4J5TA 1SNZA 4MMIA 3VDCA 1YGAA 2WVXA 1X1JA 1JZ7A 2BRWA 4FNVA 1OJNA 3VDAA 4OZVA 3IAQA 2WVXB 4OJZA 2CISA 1NSXA 1RWAA 1CB8A 1F9GA 2E24A 1NSUA 3BGAA 3BLCA 2WMJA 3NNBA 2WMIB 1W3YA 1I8QA 1K1WA 3VD5A 2Q1FA 2X03A 3E1F1 3IMHA 3NJXA 3DYMA 4BZHA 1PX3A 1J0MA 2WDAA 1K1YA 1NSZA 3DCDA 4DUWA 4DUVA 1JZ4A 1JYNA 1LXMA 1PX4A 5JMDA 3T09A 2HTBA 3OBAA 1JOVA 1ULVA 1NSVA 1N7OA 1OJPA 2XSGA 1HN1A 2FUTA 2WW3A 2WW2A 4D6GA 3DYOA 2WMIA 1Z45A 4OK2A 3I3DA 4D6CA 2D73A 3NREA 3T0DA 1HM2A 2CIQA 3WFAA 1HMWA 3I3BA 1JYXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D6E A;  1N7Q A;  1JZ6 A;  4OZW A;  3MUY 1;  3MV1 1;  3VD7 A;  3NJV A;  2ZXQ A;  3J7H A;  1N7R A;  1RWG A;  1NSS A;  3OB8 A;  4E1Y A;  3NFV A;  1TXK A;  3A24 A;  1DP0 A;  5JMF A;  1NS7 A;  1QAZ A;  1LF6 A;  3IAP A;  1HV6 A;  4MMH A;  1UG9 A;  3T0A A;  2WCO A;  4D72 A;  3T2Q A;  1F1S A;  3VSN A;  2WMF A;  1MMZ A;  2WW1 A;  1YQ2 A;  2WVY A;  2WMK A;  1NSM A;  3DYP A;  4AQ0 A;  1HM3 A;  2WW0 A;  1JZ3 A;  3VD4 A;  1L7K A;  1NS0 A;  1RWC A;  2BRV X;  1NSR A;  3E7J A;  1RW9 A;  2FUQ A;  4D6I A;  1RWH A;  1LF9 A;  4RNL A;  3MV0 1;  4BZF A;  3VD9 A;  2WVZ A;  3AFL A;  1MN0 A;  1NS2 A;  4D71 A;  1NS8 A;  3DEC A;  3T2O A;  3MUZ 1;  1LUR A;  1SO0 A;  2CIR A;  2WMH A;  3MWX A;  1C82 A;  3E80 A;  3A0O A;  3OS7 A;  1JZ2 A;  1MMX A;  4D6F A;  1F4A A;  3T0B A;  1N7N A;  3VD3 A;  2JKE A;  4D6J A;  2WZS A;  3ECQ A;  1EGU A;  4OK4 A;  4NEI A;  1RWF A;  4F10 A;  3Q1N A;  4BZE A;  4D6D A;  3SEP A;  1JYV A;  3I3E A;  1JYW A;  1NS4 A;  4BZG A;  3K25 A;  1N7P A;  2BRP A;  1LXK A;  2XHN A;  3VDB A;  1K1X A;  2HTA A;  1LOH A;  2ZQ0 A;  3CZJ A;  1HMU A;  4D6H A;  1F4H A;  5E1Q A;  1X1H A;  4TTG A;  1OJO A;  1X1I A;  5A1A A;  1OJM A;  3VSM A;  4F13 A;  1J0N A;  2JKP A;  1NKG A;  2JKA A;  1MMY A;  1L7J A;  2WMG A;  1JZ5 A;  1JZ8 A;  3T2P A;  1HN0 A;  3T08 A;  1MMU A;  2E22 A;  4DUX A;  1SNZ A;  4MMI A;  3VDC A;  1YGA A;  2WVX A;  1X1J A;  1JZ7 A;  2BRW A;  4FNV A;  1OJN A;  3VDA A;  4OZV A;  3IAQ A;  2WVX B;  4OJZ A;  2CIS A;  1NSX A;  1RWA A;  1CB8 A;  1F9G A;  2E24 A;  1NSU A;  3BGA A;  2WMJ A;  3NNB A;  2WMI B;  1W3Y A;  1I8Q A;  1K1W A;  3VD5 A;  2Q1F A;  2X03 A;  3E1F 1;  3IMH A;  3NJX A;  3DYM A;  4BZH A;  1PX3 A;  1J0M A;  2WDA A;  1K1Y A;  1NSZ A;  3DCD A;  4DUW A;  4DUV A;  1JZ4 A;  1JYN A;  1LXM A;  1PX4 A;  5JMD A;  3T09 A;  2HTB A;  3OBA A;  1JOV A;  1ULV A;  1NSV A;  1N7O A;  1OJP A;  2XSG A;  1HN1 A;  2FUT A;  2WW3 A;  2WW2 A;  4D6G A;  3DYO A;  2WMI A;  1Z45 A;  4OK2 A;  3I3D A;  4D6C A;  2D73 A;  3NRE A;  3T0D A;  1HM2 A;  2CIQ A;  3WFA A;  1HMW A;  3I3B A;  1JYX A; 
#chains in the Genus database with same CATH topology
 4D6E A;  1N7Q A;  3P5P A;  2E2U A;  4OZW A;  4GTM B;  3DYP A;  3MUY 1;  1KSC A;  1N4P B;  3NJV A;  4BOJ A;  1TQW A;  2ZXQ A;  1HXG A;  3J7H A;  3DSX B;  5CA3 A;  1TNY B;  3VW5 A;  3ANK A;  3OB8 A;  2H6G B;  4E1Y A;  2JG0 A;  3X40 A;  2CWT A;  4DLO A;  5IKA A;  1S63 B;  3K7X A;  1FMI A;  4AQ0 A;  1SPU A;  5ILZ A;  3KSL B;  3H2W A;  4ZH5 A;  1NS7 A;  4ZH1 A;  3LOY A;  4CJ1 A;  2G02 A;  3S9V A;  3T0U A;  2ONG A;  1LF6 A;  3HXD B;  3IAP A;  1N94 B;  5IL3 A;  3PZ2 B;  5MEH A;  2FUZ A;  3TY1 A;  1V7W A;  3VD4 A;  2WW0 A;  3BVU A;  1KS8 A;  2CFD A;  4TF4 A;  3N0G A;  1RW9 A;  3W7W A;  1MN0 A;  4D71 A;  3MUZ 1;  3QXF A;  1K72 A;  3PMM A;  2Z07 A;  1MZC B;  2WMH A;  1C82 A;  2J5C A;  3MI6 A;  4BTW A;  3A0O A;  2WO0 A;  2E2T A;  2CG0 A;  2P0V A;  1WMP A;  4D6F A;  1F4A A;  3T0B A;  3D52 A;  4D6J A;  4YCR A;  4F10 A;  3DDG A;  4D6D A;  3I3E A;  3SDQ A;  3M71 A;  4BTY A;  4K35 A;  1TQU A;  4GTQ B;  1UMP A;  3E73 A;  3S4C A;  1N7P A;  2BRP A;  2DRO A;  2OW6 A;  3TF4 A;  2HTA A;  4FNT A;  2XWJ B;  1TN6 B;  3AMO A;  4AYP A;  4LIX A;  1QX1 A;  1IA6 A;  2A73 B;  1FAE A;  3AMO B;  1IS9 A;  3X3X A;  5A1A A;  1OJM A;  3M7L A;  1NL4 B;  3W5M A;  3BVV A;  2QNO A;  2XQW A;  3M7B A;  1PU4 A;  1SA4 B;  2H6I B;  1HN0 A;  2WYN A;  3T08 A;  2E22 A;  2F7P A;  3WKI A;  3P2C A;  2D5J A;  4BOK A;  2CIQ A;  3SQC A;  1IVW A;  4OZV A;  3IAQ A;  1N22 A;  3H7L A;  2EAE A;  2RI9 A;  3GT5 A;  3X3Z A;  2AFA A;  2JJB A;  4KKJ A;  1RWA A;  2E24 A;  3CV5 A;  1C3D A;  3HXC B;  5FO7 B;  2DRQ A;  4AYO A;  3X41 A;  1W4N A;  3SXX A;  1FBO A;  1O1S B;  1O6H A;  1X81 B;  1SII A;  3VD5 A;  4FNU A;  3E1F 1;  1H37 A;  3NJX A;  4BZH A;  1JCS B;  2KXS A;  3DST B;  1K1Y A;  1NSZ A;  5DGQ A;  3E32 B;  4GTT B;  4XUV A;  3QPF A;  4Z4L A;  3W7X A;  1PX4 A;  1JYN A;  5JMD A;  2CQS A;  4GTP B;  3U7V A;  1RKY A;  1N1Z A;  1KWF A;  2DRR A;  1NSV A;  1LTX B;  1XW2 A;  2ZIR B;  3CU7 A;  4LNV A;  3ACS A;  2AHF A;  4D6G A;  4K3A A;  4MU9 A;  2FBA A;  2WMI A;  4FUS A;  3I3D A;  2F6D A;  3M7C A;  4KFE A;  1DL2 A;  1HM2 A;  1FT1 B;  2H6F B;  4LNB B;  5IK9 A;  3WFA A;  3E33 B;  1AVK A;  5KKB A;  1KRE A;  1DCE B;  1IA7 A;  3Q7F B;  3PQI A;  1NSS A;  3WA3 A;  1JRQ A;  3N0F A;  1TXK A;  1SIH A;  2GOX A;  2OOV C;  4DOE A;  2OQE C;  3M77 A;  2PN5 A;  3A24 A;  5JMF A;  1SA5 B;  2CFL A;  1GAI A;  4FXG B;  3G4D A;  4FXK B;  3EJR A;  1HTY A;  1UG9 A;  4GAX A;  3HI7 A;  4Q88 A;  2YIK A;  4D72 A;  1GXM A;  2WGQ A;  2F0Y B;  3VSN A;  1GSZ A;  2WMF A;  3EQA A;  3QDE A;  1MMZ A;  1O79 A;  1N4R B;  2V3N A;  3KSQ B;  2WMK A;  1NSM A;  4D4A A;  2E2V A;  4KTP A;  3SDU A;  2RGK A;  3QFZ A;  1L7K A;  1NS0 A;  2F7R A;  3E7J A;  4BZF A;  3VD9 A;  1VD5 A;  2WY7 A;  3MV0 1;  2OQE A;  5ILJ A;  3HXF B;  3Q79 B;  1V5D A;  1W7C A;  1TNU B;  1WZZ A;  1LD8 B;  5FOB B;  3MWX A;  4M76 A;  1H14 A;  1JS4 A;  5IM1 A;  3DX0 A;  3KQ4 A;  1H36 A;  3WUX A;  1MMX A;  1UI7 A;  1GXO A;  1D6Y A;  3QT9 A;  2JKE A;  2WZS A;  3SAE A;  1EGU A;  3RX5 A;  3DDF A;  4KFF A;  4NEI A;  3PYA A;  2IEJ B;  3D4Z A;  4FNR A;  3WIR A;  2BB6 A;  5ILH A;  1JCR B;  3E37 B;  3D50 A;  4BZG A;  2YFO A;  1LXK A;  2XHN A;  1N4S B;  3K11 A;  3M7E A;  1K1X A;  2ZQ0 A;  3CZJ A;  3DRA B;  4D6H A;  1F4H A;  5DHK A;  5M7Y A;  1W6J A;  3M01 A;  4ZRP A;  2BB5 A;  1X1H A;  3WVF A;  4MBG B;  1O1T B;  3PGB A;  5GW7 A;  3BS6 A;  3RSY A;  1H35 A;  1H12 A;  2JKP A;  3BVX A;  4YDO B;  3SFY B;  3QR8 A;  1MMY A;  2WMG A;  3QT3 A;  2JKA A;  1OAC A;  1JZ5 A;  1JZ8 A;  3T2P A;  1QAK A;  2V8I A;  3WC3 A;  3QSP A;  1N4Q B;  1AVL A;  3DX1 A;  4CE7 A;  4J5T A;  5CD2 A;  1UI8 A;  2D8L A;  1X1J A;  3BUI A;  1G9G A;  1JZ7 A;  3KII A;  1OJN A;  5C05 A;  1W5Z A;  5FO8 B;  1GA2 A;  4OJZ A;  2CIS A;  2C10 A;  3WKG A;  1IVV A;  3E34 B;  2AHG A;  4EL8 A;  3BGA A;  3DX3 A;  3M02 A;  4QT9 A;  3NNB A;  1W3Y A;  2H6H B;  4GTO B;  1CEM A;  1DOG A;  2CFW A;  2D1W A;  1WMN A;  1D8D B;  2XN1 A;  1R33 A;  3DYM A;  4GTV B;  1PX3 A;  1J0M A;  1D6U A;  1O6R A;  1RQ5 A;  1LXM A;  3SFX B;  1QAF A;  2CFG A;  2ZBL A;  3OBA A;  1ULV A;  2G0D A;  1AYX A;  1FPP B;  1OJP A;  2WYI A;  1G9J A;  3HXE B;  3T0D A;  1AGM A;  4AYQ A;  2XFG A;  3W7T A;  1IQY A;  1HMW A;  1FT2 B;  1L2A A;  3BUB A;  1JZ6 A;  1LD7 B;  4ZRQ A;  2OKX A;  4D1J A;  2F1A A;  3M76 A;  2FYV A;  1O7D D;  4KFD A;  1V7V A;  2SQC A;  2CWU A;  1RWG A;  2I07 B;  3PZ1 B;  4TXT A;  3EJP A;  2GH4 A;  2C11 A;  3NFV A;  1W6C A;  4D4D A;  5IKH A;  1PS3 A;  3QXQ A;  5ILY A;  4D1I A;  3X3Y A;  4KTR A;  4V1R A;  1FO2 A;  2YX9 A;  4LNG B;  1HV6 A;  4MMH A;  1RJO A;  5DHI A;  3CZN A;  1TQT A;  2WCO A;  3EU8 A;  2WY8 A;  3EJS A;  3EJQ A;  1UT9 A;  3X17 A;  1YQ2 A;  2WVY A;  2CG1 A;  1JZ3 A;  3P5R A;  4GTR B;  2F18 A;  4EHM B;  1RWC A;  2BRV X;  1TNO B;  1FO3 A;  1NSR A;  4D6I A;  1RWH A;  4RNL A;  2WVZ A;  3AFL A;  5JPM B;  1N9E A;  1NS2 A;  1N9A B;  1N1B A;  1V5C A;  1LUR A;  1HXC A;  1SO0 A;  3M74 A;  1L1Y A;  3M72 A;  5GY3 A;  3BLB A;  3OS7 A;  2CQT A;  2F7Q A;  1KSI A;  4CJ0 A;  3VD3 A;  1N7N A;  5FO9 B;  1DYU A;  1QWN A;  1TQS A;  1KZP B;  1KSD A;  3NBJ A;  4OK4 A;  1RWF A;  1TNZ B;  3UD2 A;  2WOH A;  1GXN A;  4BZE A;  3M78 A;  2KXR A;  3ALA A;  3SEP A;  3ANI A;  3QRY A;  4WVB A;  1JYV A;  1JYW A;  1WU4 A;  5IL8 A;  5ILD A;  1JCQ B;  1R76 A;  3K25 A;  3M75 A;  1IVX A;  1WU6 A;  3BUP A;  3VDB A;  2XN2 A;  1LOH A;  3G4F A;  1GHQ A;  2PMV A;  1HMU A;  2R2L B;  3KLS A;  3SX1 A;  1XWQ A;  3HXB B;  3SDT A;  1GAH A;  1G6I A;  5CZL A;  3WKF A;  4TTG A;  1X1I A;  3G6J B;  3DSW B;  2ZL8 A;  3REN A;  3VSM A;  4F13 A;  1QBQ B;  1L7J A;  1V7X A;  1W6K A;  4DUX A;  1SNZ A;  1TN8 B;  3VDC A;  1YGA A;  2BT3 A;  2CFK A;  2WVX A;  1H3C A;  3CIH A;  1HX9 A;  2XN0 A;  2ZZR A;  4FNV A;  3WKH A;  1WMO A;  1TNB B;  3S4B A;  3CZS A;  1R34 A;  1F9G A;  4WU0 A;  1N95 B;  2EAB A;  3PYB A;  3E30 B;  3BLC A;  2WMJ A;  2WMI B;  2VN4 A;  3RJ3 A;  3DSV B;  3EZ8 A;  1H3B A;  3ANJ A;  4FNS A;  1K1W A;  2RDY A;  3OED A;  3LVT A;  1QQF A;  1F9O A;  3M00 A;  2WYH A;  3DX2 A;  4BTX A;  2FV0 A;  3IMH A;  3MPH A;  3W7S A;  1H3A A;  4AYR A;  2WDA A;  3EUV B;  2GZ6 A;  2DRS A;  5IK6 A;  3DX4 A;  5KBP A;  1H13 A;  4L0G A;  1US1 A;  3T09 A;  2XWB B;  3NBB A;  1HWW A;  1FCE A;  4D4C A;  2FUT A;  3RX8 A;  4L6X A;  3KBU C;  3EU5 B;  5DGR A;  1KZO B;  2WW2 A;  1QAL A;  2V8K A;  4OK2 A;  3T33 A;  4D6C A;  2D73 A;  3ON6 A;  3RX7 A;  1KFG A;  3N9H A;  3I3B A;  1JYX A;  3D3I A;  5EAS A;  2W0Q A;  5EAT A;  3QG0 A;  3MV1 1;  3D4Y A;  1FBW A;  2A8Z A;  3VD7 A;  3LZ9 A;  4FJQ A;  3PZ3 B;  3UD1 A;  3K5T A;  3D5R A;  1FP3 A;  1N7R A;  3SDR A;  1NI1 B;  3DSU B;  4WVC A;  4EV2 A;  3OXU A;  1A2V A;  1IQX A;  1CLC A;  1O5M B;  1QWU A;  3WIQ A;  4FNQ A;  3WIW A;  3KBT C;  1HXK A;  3Q75 B;  1DP0 A;  3AFJ A;  4C1S A;  4Q2B A;  4D8O A;  1N21 A;  1QAZ A;  2NVP A;  5IK0 A;  2F1B A;  3T0A A;  1IVU A;  1H54 A;  2F7O A;  3T2Q A;  1F1S A;  2WW1 A;  2BBC A;  1HM3 A;  2NOJ A;  3GLY A;  1LF9 A;  2FUQ A;  1GLM A;  1TN7 B;  1S64 B;  2EAC A;  3T2O A;  4WVA A;  1NS8 A;  3DEC A;  4KKI A;  3QFY A;  4DOD A;  2CIR A;  3E80 A;  3EJT A;  1F9D A;  2ONH A;  2Y74 A;  1JZ2 A;  1TF4 A;  1WU5 A;  2JF4 A;  3RRS A;  3ECQ A;  1O1R B;  2B39 A;  3BVT A;  4V1S A;  3Q1N A;  3E6U A;  4GL3 A;  1O6Q A;  3SDV A;  1N24 A;  3PZ4 B;  1N23 A;  1NS4 A;  1HCU A;  3BUQ A;  5GZK A;  4DLQ A;  2OOV A;  4UFC A;  3C72 B;  2ZIS B;  1NXC A;  3Q73 B;  4ONT A;  3KN4 A;  1KKT A;  3D5S A;  1W6G A;  3X42 A;  3F59 A;  5E1Q A;  4EV5 A;  2ALW A;  1OJO A;  3GZK A;  3M73 A;  4JJJ A;  2WIN B;  5E2J A;  5EAU A;  1W2Z A;  3S4D A;  1J0N A;  4L9P B;  1NKG A;  1G87 A;  1AV4 A;  2RI8 A;  1TQV A;  3BUD A;  5M7I A;  3WA2 X;  1MMU A;  4D94 A;  3ACT A;  2VN7 A;  4MMI A;  1TU5 A;  2B4F A;  3HIG A;  2WII B;  2BRW A;  4Z4J A;  3Q78 B;  2BED B;  3VXD A;  3D51 A;  3VDA A;  5ILK A;  4ZG8 A;  1KRF A;  2WVX B;  1IU7 A;  4DI5 A;  3DPY B;  1SQC A;  1D6Z A;  1NSX A;  1CB8 A;  3W7U A;  1NSU A;  3BVW A;  3HII A;  1I8Q A;  3S4A A;  1HXA A;  2PNC A;  3H3K A;  2Q1F A;  1QSJ A;  2X03 A;  5AGD A;  2WOF A;  4FNP A;  1N20 A;  1EKM A;  1HZF A;  3DCD A;  4DUW A;  4DUV A;  4D4B A;  2EAD A;  2CWV A;  1XWT A;  1LVN A;  2FV1 A;  1JZ4 A;  5ILI A;  1H39 A;  3A3V A;  3QWT A;  1D8E B;  2HTB A;  2V8J A;  1JOV A;  2Y73 A;  1N7O A;  5JPN B;  2XSG A;  1HN1 A;  2WW3 A;  3Q7A B;  2OW7 A;  4RNQ A;  3DYO A;  2V3P A;  4YDE B;  1NC5 A;  1Z45 A;  2YFN A;  3NRE A;  3EJU A;  1X9D A;  3DSS B;  3W5N A;  4GTS B; 
#chains in the Genus database with same CATH homology
 4D6E A;  1N7Q A;  1JZ6 A;  4OZW A;  3MUY 1;  3MV1 1;  3VD7 A;  3NJV A;  2ZXQ A;  3J7H A;  1N7R A;  1RWG A;  1NSS A;  3OB8 A;  4E1Y A;  3NFV A;  1TXK A;  3A24 A;  1DP0 A;  5JMF A;  1NS7 A;  1QAZ A;  1LF6 A;  3IAP A;  1HV6 A;  4MMH A;  1UG9 A;  3T0A A;  2WCO A;  4D72 A;  3T2Q A;  3TY1 A;  1F1S A;  3VSN A;  2WMF A;  1MMZ A;  2WW1 A;  1YQ2 A;  2WVY A;  2WMK A;  1NSM A;  3DYP A;  4AQ0 A;  1HM3 A;  2WW0 A;  1JZ3 A;  3VD4 A;  1L7K A;  1NS0 A;  1RWC A;  2BRV X;  1NSR A;  3E7J A;  1RW9 A;  2FUQ A;  4D6I A;  1RWH A;  1LF9 A;  4RNL A;  3MV0 1;  4BZF A;  3VD9 A;  2WVZ A;  3AFL A;  1MN0 A;  1NS2 A;  4D71 A;  1NS8 A;  3DEC A;  3T2O A;  3MUZ 1;  1LUR A;  1SO0 A;  2CIR A;  2WMH A;  3MWX A;  1C82 A;  3E80 A;  3A0O A;  3OS7 A;  1JZ2 A;  1MMX A;  4D6F A;  1F4A A;  3T0B A;  1N7N A;  3VD3 A;  2JKE A;  4D6J A;  2WZS A;  3ECQ A;  1EGU A;  4OK4 A;  4NEI A;  1RWF A;  4F10 A;  3Q1N A;  4BZE A;  4D6D A;  3SEP A;  1JYV A;  3I3E A;  1JYW A;  1NS4 A;  4BZG A;  3K25 A;  1N7P A;  2BRP A;  1LXK A;  2XHN A;  3VDB A;  1K1X A;  2HTA A;  1LOH A;  2ZQ0 A;  3CZJ A;  1HMU A;  4D6H A;  1F4H A;  5E1Q A;  3WVF A;  1X1H A;  4TTG A;  1OJO A;  1X1I A;  3BS6 A;  5A1A A;  1OJM A;  3VSM A;  4F13 A;  1J0N A;  2JKP A;  1NKG A;  2JKA A;  1MMY A;  1L7J A;  2WMG A;  1JZ5 A;  1JZ8 A;  3T2P A;  1HN0 A;  3T08 A;  1MMU A;  2E22 A;  4DUX A;  4J5T A;  1SNZ A;  4MMI A;  3VDC A;  1YGA A;  2WVX A;  1X1J A;  1JZ7 A;  2BRW A;  4FNV A;  1OJN A;  3VDA A;  4OZV A;  3IAQ A;  2WVX B;  4OJZ A;  2CIS A;  1NSX A;  1RWA A;  1CB8 A;  1F9G A;  2E24 A;  1NSU A;  3BGA A;  3BLC A;  2WMJ A;  3NNB A;  2WMI B;  1W3Y A;  1I8Q A;  1K1W A;  3VD5 A;  2Q1F A;  2X03 A;  3E1F 1;  3IMH A;  3NJX A;  3DYM A;  4BZH A;  1PX3 A;  1J0M A;  2WDA A;  1K1Y A;  1NSZ A;  3DCD A;  4DUW A;  4DUV A;  1JZ4 A;  1JYN A;  1LXM A;  1PX4 A;  5JMD A;  3T09 A;  2HTB A;  3OBA A;  1JOV A;  1ULV A;  1NSV A;  1N7O A;  1OJP A;  2XSG A;  1HN1 A;  2FUT A;  2WW3 A;  2WW2 A;  4D6G A;  3DYO A;  2WMI A;  1Z45 A;  4OK2 A;  3I3D A;  4D6C A;  2D73 A;  3NRE A;  3T0D A;  1HM2 A;  2CIQ A;  3WFA A;  1HMW A;  3I3B A;  1JYX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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