2WDAA

The x-ray structure of the streptomyces coelicolor a3 chondroitin ac lyase in complex with chondroitin sulphate
Total Genus 261
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
261
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PUTATIVE SECRETED LYASE
publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces violaceoruber
molecule tags Lyase
total genus 261
structure length 742
sequence length 742
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2009-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2wdaA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2wdaA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2wdaA02
4AQ0A 1NS2A 3E7JA 1EGUA 1RWGA 1X1JA 3NJXA 3T0AA 1F9GA 1LXMA 3A0OA 1SO0A 4RNLA 4MMHA 5JMDA 3T2OA 2CIRA 2WMIB 2HTBA 1HN0A 2FUTA 2WVZA 3OS7A 4DUVA 2JKPA 3VD7A 1N7OA 1RWCA 4OZWA 2XHNA 2XSGA 1JZ7A 1F4HA 1K1XA 4F13A 2WMGA 1JYWA 1JOVA 2E24A 3K25A 3DYOA 1RWAA 2WMFA 3VDCA 4FNVA 1HV6A 4BZFA 2WW3A 1W3YA 2CIQA 3DYPA 3VD4A 1NSZA 2HTAA 1HMUA 1MMXA 2WZSA 3DECA 1JZ5A 3AFLA 2JKAA 3T2PA 1LF9A 4D71A 1PX3A 1NSSA 3IAQA 3T08A 1OJPA 3VDBA 3NFVA 3T0BA 3NJVA 5JMFA 2WMHA 3I3BA 2WMKA 4E1YA 3OBAA 2BRVX 3BGAA 3SEPA 3I3DA 4D6GA 1OJMA 3MWXA 2BRPA 2WVYA 1RWFA 1TXKA 3DYMA 3E1F1 1J0NA 3ECQA 1SNZA 1RWHA 1K1WA 3T2QA 1NS0A 4MMIA 2X03A 2WW1A 2ZXQA 4TTGA 5A1AA 2WMIA 4D72A 4D6FA 1YQ2A 3MV01 1OJNA 4OJZA 2BRWA 1N7PA 1L7KA 2D73A 1Z45A 3OB8A 4D6IA 1C82A 4D6EA 4DUXA 4BZEA 4D6JA 1JZ3A 1N7NA 1DP0A 1UG9A 1MMZA 5E1QA 1LURA 2WVXA 1MMUA 1HM3A 3DCDA 4D6CA 4NEIA 2WCOA 4F10A 2WW2A 1K1YA 2ZQ0A 3E80A 3VD9A 3IAPA 3MUZ1 1N7RA 1NSRA 3WFAA 2FUQA 1NSUA 1ULVA 1JYVA 3VDAA 4OK2A 4OK4A 3T09A 2WMJA 1NS4A 3Q1NA 1JZ4A 1JYNA 3J7HA 1QAZA 1LF6A 2JKEA 1HM2A 3VD5A 1JZ6A 1NS7A 1LOHA 3MV11 3A24A 1X1IA 3VSNA 3VD3A 3NREA 2E22A 4D6HA 3CZJA 3MUY1 1NS8A 1JZ8A 4D6DA 1F1SA 1HN1A 2WW0A 1X1HA 4BZHA 1L7JA 1I8QA 1OJOA 1J0MA 1NSMA 1YGAA 3I3EA 4DUWA 1JZ2A 3T0DA 1RW9A 1F4AA 1NKGA 1HMWA 1MN0A 1NSVA 2WDAA 4BZGA 3NNBA 2CISA 2WVXB 1JYXA 4OZVA 2Q1FA 1NSXA 1CB8A 1N7QA 1PX4A 3VSMA 1MMYA 3IMHA 1LXKA
chains in the Genus database with same CATH superfamily
3SDVA 3AFJA 4C1SA 1TNUB 3WC3A 4WVBA 3E7JA 1RWGA 4FNTA 2FV0A 3M77A 3W7XA 1UI7A 3GT5A 4BTXA 1FO2A 2WYNA 2CIRA 2OQEA 4DUVA 1HN0A 3M75A 3M7BA 2DRRA 1IQYA 3DX0A 2CQSA 2JKPA 4D4AA 2XSGA 4LNGB 2OKXA 1TNBB 1FT2B 4KKJA 4EV2A 4CJ0A 3WKHA 2E2UA 4MBGB 3DYOA 1TQWA 4KKIA 1TQSA 4ZG8A 4FNSA 1HXAA 2V3PA 1GAHA 1R34A 1UI8A 5M7IA 1HXCA 4AYQA 1MMXA 2OW7A 3DECA 4FXKB 1MZCB 3W7UA 4K3AA 3ACSA 4GTPB 1QWNA 3UD1A 4D71A 1PX3A 4JJJA 2F6DA 3T08A 3M01A 3E73A 1N95B 3I3BA 1V7XA 1LVNA 1KFGA 3RX8A 2PNCA 1IVUA 3BGAA 2PMVA 3QT9A 3CZSA 2JJBA 1IVXA 2BRPA 1RWFA 1XW2A 3E1F1 3BUBA 3SDUA 1SNZA 1LTXB 1FCEA 3K5TA 1NS0A 3QDEA 4MMIA 5IM1A 3X41A 3E33B 1FMIA 3X17A 5A1AA 2WMIA 2BBCA 4D6FA 5EAUA 1O1RB 3BLCA 2BRWA 3SX1A 2D73A 1KZOB 3P5PA 1X9DA 3OB8A 3WKFA 1C82A 1FBOA 2AFAA 3S4AA 1WU6A 3G6JB 1DL2A 1KSCA 1O79A 1UG9A 3G4DA 1D8EB 1GA2A 1LURA 3DX3A 1C3DA 3DCDA 1V7VA 2AHGA 4J5TA 1SIIA 4D6CA 4NEIA 3T33A 4D94A 3PGBA 3S4BA 3E80A 3WUXA 3VD9A 3WFAA 2FUQA 3DSVB 1NSUA 2JF4A 3ANIA 3BVTA 4XUVA 2KXRA 2WMJA 2RDYA 3EZ8A 1JYNA 2NOJA 1R76A 1NL4B 1QBQB 1LF6A 5EATA 2F0YB 3DX2A 1N4QB 2CWVA 3ANKA 4V1RA 1G9JA 3E32B 3PZ4B 4GL3A 2G0DA 1X1IA 3DPYB 4M76A 2CWTA 3NBJA 3P2CA 3H2WA 3OEDA 4D6HA 3CZJA 1D6UA 3MUY1 4KFEA 2WYIA 3RX5A 1IA6A 1HN1A 4GTVB 1YGAA 3HXCB 1JZ2A 1CLCA 1HXKA 3SDRA 4D4CA 1EKMA 3WA2X 5KKBA 3KIIA 3QWTA 1HCUA 1MN0A 1NSVA 2WDAA 3DX4A 3M02A 2D8LA 2CISA 3CU7A 2ALWA 3BVUA 4BZGA 2VN4A 1N4SB 4OZVA 1V5CA 3RENA 4CJ1A 1G6IA 1QX1A 2WYHA 1PX4A 2BEDB 3Q7AB 2WINB 1O6HA 3AMOB 2Z07A 3W5NA 2EACA 1LXKA 4ZRPA 1TQVA 3BUIA 1EGUA 1HWWA 5DGQA 1SO0A 3SFYB 3BUQA 4UFCA 5JMDA 2RGKA 3OS7A 5FOBB 1N24A 1DCEB 3GZKA 3M76A 3D4ZA 3BVVA 3VD7A 3M71A 3EJQA 1F4HA 1H3BA 3DSUB 3VXDA 1XWQA 3K25A 4TXTA 4FNUA 3TY1A 1TNOB 4FNVA 3RRSA 2WW3A 3PYBA 2WY7A 4DLQA 2YIKA 1NSZA 1W6JA 2C11A 2CFKA 2HTAA 4EHMB 1HZFA 1W2ZA 2JKAA 4FNQA 3T2PA 1QWUA 1H3AA 3IAQA 3PZ1B 3H7LA 3NFVA 2W0QA 3NJVA 5JMFA 2F1AA 4FUSA 3EJPA 3OBAA 1KSIA 2EADA 1O1TB 2I07B 3CIHA 5DHIA 3UD2A 1WMNA 3LVTA 4D6GA 1DYUA 1IS9A 3SQCA 2CQTA 3CV5A 5CZLA 1TQTA 1TXKA 1NXCA 2Y73A 4GTSB 1IVWA 1WMOA 2A8ZA 1K1WA 4DOEA 3E37B 4BOKA 5ILZA 2FBAA 3WIRA 4D72A 4Z4LA 1YQ2A 5IL8A 1KZPB 1RKYA 3E6UA 3BVXA 1FT1B 1N7PA 1L7KA 1RJOA 5ILHA 1N9EA 1HX9A 4ONTA 1AV4A 2F18A 3BLBA 2P0VA 3Q75B 3S9VA 4D6JA 1IQXA 3EU8A 1N94B 5E1QA 1TN8B 1N9AB 1GAIA 1MMUA 1DOGA 1HM3A 1JCSB 4YDOB 3CZNA 1US1A 3HXFB 1V7WA 3IAPA 1N7RA 3U7VA 3MUZ1 4ZRQA 2OOVA 1KREA 3M73A 2XWBB 3QRYA 3HXDB 3QXQA 5E2JA 3X40A 1N20A 5MEHA 4BTYA 1H12A 3M74A 4GTOB 4KTPA 1JZ4A 2B39A 2F7RA 3J7HA 2JKEA 1HM2A 3VD5A 3RSYA 5GY3A 2GH4A 3OXUA 1WU4A 5GZKA 2NVPA 3SAEA 2AHFA 1H39A 3VD3A 1FAEA 3PMMA 2BB6A 3W7SA 1NS8A 2H6GB 3H3KA 3PYAA 4D6DA 3BVWA 3M72A 1X1HA 1J0MA 3C72B 2OOVC 3W5MA 3HXEB 1RW9A 1F4AA 5ILKA 4LNBB 1SQCA 2FYVA 5FO8B 4ZH5A 3EJTA 5FO7B 3E30B 1JYXA 2FUZA 1KRFA 1UMPA 1N4PB 1CB8A 3LZ9A 1K72A 3BS6A 3IMHA 3E34B 2DRSA 1HXGA 2V8JA 1PU4A 3D50A 1NS2A 2R2LB 1CEMA 3K11A 1X1JA 4WVAA 1F9GA 1L1YA 1KWFA 3A0OA 4RNLA 3WA3A 4MMHA 2XQWA 2XFGA 2WVZA 3T2OA 2FUTA 1AVLA 3EUVB 2E2TA 4FNRA 3BUDA 5AGDA 5CA3A 1SA4B 3WIQA 4OZWA 3WIWA 3W7TA 1WZZA 2XN0A 4F13A 1JCQB 1RQ5A 2RI8A 5IL3A 1JOVA 1W6GA 4GTMB 4KFDA 2RI9A 3S4DA 1RWAA 2WMFA 3VDCA 3SXXA 3X3ZA 2CG1A 4BZFA 1GXNA 1W3YA 1SIHA 2CIQA 3DYPA 1R33A 3VD4A 5C05A 4WU0A 4WVCA 1LD7B 1NC5A 2C10A 3S4CA 4LNVA 1A2VA 2H6IB 2WOFA 1NSSA 1TF4A 3ANJA 3VDBA 1W4NA 3D51A 3MPHA 3DDFA 4E1YA 5DGRA 5GW7A 3M7EA 3I3DA 1S64B 4D4DA 3AMOA 3SDQA 3DYMA 1IA7A 1GLMA 3D4YA 3HXBB 3ECQA 3WKIA 1G87A 2ZXQA 2ZIRB 1D6ZA 3QT3A 3KSLB 1NI1B 1V5DA 1IU7A 3MV01 1OJNA 1H35A 2IEJB 1N22A 2ZBLA 2SQCA 4BOJA 4D6IA 2F7PA 4D6EA 4BZEA 2WOHA 3KSQB 4YCRA 1FO3A 3EU5B 1MMZA 4Z4JA 3D3IA 1H36A 3HIGA 2WVXA 1QALA 3X42A 1W6KA 3DX1A 1SPUA 3KLSA 1N1ZA 4YDEB 4F10A 1HTYA 2CG0A 1NSRA 5M7YA 2ONHA 1QAFA 1SA5B 3VDAA 4OK2A 4OK4A 3DRAB 1GSZA 1NS4A 3Q1NA 2H6FB 2XN2A 1N21A 3ACTA 3D52A 3X3YA 4EV5A 1H14A 1XWTA 2A73B 1JZ6A 4D1JA 1LOHA 3QSPA 1QAKA 2WO0A 3MV11 3WKGA 1KSDA 1TNZB 1GXMA 3VSNA 2GOXA 5FO9B 1VD5A 2E22A 1O7DD 3SDTA 3KBTC 2D5JA 4DI5A 3K7XA 4AYOA 5IK6A 2H6HB 1F1SA 2WW0A 4EL8A 4BZHA 1L7JA 4DUWA 1H3CA 1OJOA 2F1BA 3P5RA 3DSXB 4Q2BA 3DSTB 1NKGA 3EQAA 2V8IA 4GAXA 3PZ2B 4L0GA 1HMWA 5JPMB 1F9DA 5ILYA 3WVFA 1GHQA 1GXOA 1O5MB 1AVKA 3Q79B 4DODA 1W5ZA 1KKTA 2WGQA 3TF4A 3VSMA 2PN5A 3DSSB 1MMYA 3N0GA 3T0UA 2YFOA 4KTRA 4GTQB 4L9PB 4RNQA 3PQIA 2OQEC 3MI6A 4KFFA 4AQ0A 3X3XA 3M7LA 1OACA 3NBBA 1H37A 3NJXA 3T0AA 1FP3A 1LXMA 1N23A 1O6RA 3W7WA 4D8OA 2WMIB 2HTBA 2XN1A 1IVVA 5KBPA 1WU5A 3KBUC 3GLYA 4AYPA 3N9HA 3EJSA 1LD8B 1N7OA 1RWCA 2XHNA 2CWUA 1TU5A 2CFDA 1AGMA 4GTRB 1TNYB 1K1XA 1JZ7A 2WMGA 1JYWA 2E24A 3EJRA 5IKAA 1QQFA 1HV6A 1JCRB 1FBWA 2EAEA 2ONGA 3M78A 4FXGB 2DROA 4MU9A 1O1SB 1HMUA 2WZSA 5EASA 1JZ5A 3AFLA 3QXFA 5DHKA 1LF9A 3KQ4A 4TF4A 4BTWA 4CE7A 4LIXA 5ILIA 1OJPA 3T0BA 2XWJB 2CFGA 2WMHA 4ZH1A 2WMKA 3M7CA 2D1WA 2WY8A 2BRVX 3D5SA 4QT9A 1N4RB 3KN4A 3SEPA 3ON6A 3ALAA 1OJMA 2J5CA 2VN7A 2B4FA 1D6YA 3BUPA 1G9GA 2ZISB 3MWXA 2WVYA 3A3VA 3RJ3A 1JRQA 1J0NA 1N1BA 1RWHA 3G4FA 3T2QA 1X81B 2YX9A 1TQUA 2WW1A 2X03A 4TTGA 5CD2A 2V8KA 1KS8A 3Q73B 2F7QA 3QG0A 5ILJA 4OJZA 1UT9A 5IKHA 1Z45A 1H13A 3D5RA 4GTTB 3QFYA 4V1SA 4DUXA 1F9OA 2ZZRA 5IK0A 2KXSA 1JZ3A 1N7NA 2V3NA 2WIIB 3QPFA 1DP0A 1S63B 2EABA 2F7OA 1JS4A 2JG0A 3DDGA 4Q88A 2YFNA 1FPPB 2GZ6A 2WCOA 2WW2A 1K1YA 2ZQ0A 3HIIA 2FV1A 3HI7A 2E2VA 3PZ3B 1TN7B 1AYXA 4FNPA 1W7CA 1ULVA 2OW6A 2Y74A 1JYVA 3T09A 2BB5A 1W6CA 1QAZA 3Q78B 1TN6B 3DSWB 2G02A 4L6XA 3VW5A 1NS7A 3M00A 4K35A 3LOYA 3SFXB 3N0FA 2CFWA 3A24A 2QNOA 5ILDA 4D1IA 3NREA 1H54A 3Q7FB 4AYRA 5JPNB 1JZ8A 1WMPA 1NSMA 1I8QA 3EJUA 5IK9A 4FJQA 1PS3A 3I3EA 3F59A 2BT3A 2ZL8A 3QFZA 1L2AA 2DRQA 3NNBA 2CFLA 2WVXB 4D4BA 1D8DB 2Q1FA 3RX7A 3QR8A 4DLOA 1NSXA 1N7QA 1QSJA 1O6QA 3T0DA
chains in the Genus database with same CATH topology
4AQ0A 1NS2A 3E7JA 1EGUA 1RWGA 1X1JA 3NJXA 3T0AA 1F9GA 1LXMA 3A0OA 1SO0A 4RNLA 4MMHA 5JMDA 3T2OA 2CIRA 2WMIB 2HTBA 1HN0A 2FUTA 2WVZA 3OS7A 4DUVA 2JKPA 3VD7A 1N7OA 1RWCA 4OZWA 2XHNA 2XSGA 1JZ7A 1F4HA 1K1XA 4F13A 2WMGA 1JYWA 1JOVA 2E24A 3K25A 3DYOA 3TY1A 1RWAA 2WMFA 3VDCA 4FNVA 1HV6A 4BZFA 2WW3A 1W3YA 2CIQA 3DYPA 3VD4A 1NSZA 2HTAA 1HMUA 1MMXA 2WZSA 3DECA 1JZ5A 3AFLA 2JKAA 3T2PA 1LF9A 4D71A 1PX3A 1NSSA 3IAQA 3T08A 1OJPA 3VDBA 3NFVA 3T0BA 3NJVA 5JMFA 2WMHA 3I3BA 2WMKA 4E1YA 3OBAA 2BRVX 3BGAA 3SEPA 3I3DA 4D6GA 1OJMA 3MWXA 2BRPA 2WVYA 1RWFA 1TXKA 3DYMA 3E1F1 1J0NA 3ECQA 1SNZA 1RWHA 1K1WA 3T2QA 1NS0A 4MMIA 2X03A 2WW1A 2ZXQA 4TTGA 5A1AA 2WMIA 4D72A 4D6FA 1YQ2A 3MV01 1OJNA 3BLCA 4OJZA 2BRWA 1N7PA 1L7KA 2D73A 1Z45A 3OB8A 4D6IA 1C82A 4D6EA 4DUXA 4BZEA 4D6JA 1JZ3A 1N7NA 1DP0A 1UG9A 1MMZA 5E1QA 1LURA 2WVXA 1MMUA 1HM3A 3DCDA 4J5TA 4D6CA 4NEIA 2WCOA 4F10A 2WW2A 1K1YA 2ZQ0A 3E80A 3VD9A 3IAPA 3MUZ1 1N7RA 1NSRA 3WFAA 2FUQA 1NSUA 1ULVA 1JYVA 3VDAA 4OK2A 4OK4A 3T09A 2WMJA 1NS4A 3Q1NA 1JZ4A 1JYNA 3J7HA 1QAZA 1LF6A 2JKEA 1HM2A 3VD5A 1JZ6A 1NS7A 1LOHA 3MV11 3A24A 1X1IA 3VSNA 3VD3A 3NREA 2E22A 4D6HA 3CZJA 3MUY1 1NS8A 1JZ8A 4D6DA 1F1SA 1HN1A 2WW0A 1X1HA 4BZHA 1L7JA 1I8QA 1OJOA 1J0MA 1NSMA 1YGAA 3I3EA 4DUWA 1JZ2A 3T0DA 1RW9A 1F4AA 1NKGA 1HMWA 1MN0A 1NSVA 2WDAA 3WVFA 3NNBA 2CISA 4BZGA 2WVXB 1JYXA 4OZVA 2Q1FA 1NSXA 1CB8A 1N7QA 1PX4A 3VSMA 1MMYA 3BS6A 3IMHA 1LXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AQ0 A;  1NS2 A;  3E7J A;  1EGU A;  1RWG A;  1X1J A;  3NJX A;  3T0A A;  1F9G A;  1LXM A;  3A0O A;  1SO0 A;  4RNL A;  4MMH A;  5JMD A;  3T2O A;  2CIR A;  2WMI B;  2HTB A;  1HN0 A;  2FUT A;  2WVZ A;  3OS7 A;  4DUV A;  2JKP A;  3VD7 A;  1N7O A;  1RWC A;  4OZW A;  2XHN A;  2XSG A;  1JZ7 A;  1F4H A;  1K1X A;  4F13 A;  2WMG A;  1JYW A;  1JOV A;  2E24 A;  3K25 A;  3DYO A;  1RWA A;  2WMF A;  3VDC A;  4FNV A;  1HV6 A;  4BZF A;  2WW3 A;  1W3Y A;  2CIQ A;  3DYP A;  3VD4 A;  1NSZ A;  2HTA A;  1HMU A;  1MMX A;  2WZS A;  3DEC A;  1JZ5 A;  3AFL A;  2JKA A;  3T2P A;  1LF9 A;  4D71 A;  1PX3 A;  1NSS A;  3IAQ A;  3T08 A;  1OJP A;  3VDB A;  3NFV A;  3T0B A;  3NJV A;  5JMF A;  2WMH A;  3I3B A;  2WMK A;  4E1Y A;  3OBA A;  2BRV X;  3BGA A;  3SEP A;  3I3D A;  4D6G A;  1OJM A;  3MWX A;  2BRP A;  2WVY A;  1RWF A;  1TXK A;  3DYM A;  3E1F 1;  1J0N A;  3ECQ A;  1SNZ A;  1RWH A;  1K1W A;  3T2Q A;  1NS0 A;  4MMI A;  2X03 A;  2WW1 A;  2ZXQ A;  4TTG A;  5A1A A;  2WMI A;  4D72 A;  4D6F A;  1YQ2 A;  3MV0 1;  1OJN A;  4OJZ A;  2BRW A;  1N7P A;  1L7K A;  2D73 A;  1Z45 A;  3OB8 A;  4D6I A;  1C82 A;  4D6E A;  4DUX A;  4BZE A;  4D6J A;  1JZ3 A;  1N7N A;  1DP0 A;  1UG9 A;  1MMZ A;  5E1Q A;  1LUR A;  2WVX A;  1MMU A;  1HM3 A;  3DCD A;  4D6C A;  4NEI A;  2WCO A;  4F10 A;  2WW2 A;  1K1Y A;  2ZQ0 A;  3E80 A;  3VD9 A;  3IAP A;  3MUZ 1;  1N7R A;  1NSR A;  3WFA A;  2FUQ A;  1NSU A;  1ULV A;  1JYV A;  3VDA A;  4OK2 A;  4OK4 A;  3T09 A;  2WMJ A;  1NS4 A;  3Q1N A;  1JZ4 A;  1JYN A;  3J7H A;  1QAZ A;  1LF6 A;  2JKE A;  1HM2 A;  3VD5 A;  1JZ6 A;  1NS7 A;  1LOH A;  3MV1 1;  3A24 A;  1X1I A;  3VSN A;  3VD3 A;  3NRE A;  2E22 A;  4D6H A;  3CZJ A;  3MUY 1;  1NS8 A;  1JZ8 A;  4D6D A;  1F1S A;  1HN1 A;  2WW0 A;  1X1H A;  4BZH A;  1L7J A;  1I8Q A;  1OJO A;  1J0M A;  1NSM A;  1YGA A;  3I3E A;  4DUW A;  1JZ2 A;  3T0D A;  1RW9 A;  1F4A A;  1NKG A;  1HMW A;  1MN0 A;  1NSV A;  2WDA A;  4BZG A;  3NNB A;  2CIS A;  2WVX B;  1JYX A;  4OZV A;  2Q1F A;  1NSX A;  1CB8 A;  1N7Q A;  1PX4 A;  3VSM A;  1MMY A;  3IMH A;  1LXK A; 
#chains in the Genus database with same CATH topology
 3SDV A;  3AFJ A;  4C1S A;  1TNU B;  3WC3 A;  4WVB A;  3E7J A;  1RWG A;  4FNT A;  2FV0 A;  3M77 A;  3W7X A;  1UI7 A;  3GT5 A;  4BTX A;  1FO2 A;  2WYN A;  2CIR A;  2OQE A;  4DUV A;  1HN0 A;  3M75 A;  3M7B A;  2DRR A;  1IQY A;  3DX0 A;  2CQS A;  2JKP A;  4D4A A;  2XSG A;  4LNG B;  2OKX A;  1TNB B;  1FT2 B;  4KKJ A;  4EV2 A;  4CJ0 A;  3WKH A;  2E2U A;  4MBG B;  3DYO A;  1TQW A;  4KKI A;  1TQS A;  4ZG8 A;  4FNS A;  1HXA A;  2V3P A;  1GAH A;  1R34 A;  1UI8 A;  5M7I A;  1HXC A;  4AYQ A;  1MMX A;  2OW7 A;  3DEC A;  4FXK B;  1MZC B;  3W7U A;  4K3A A;  3ACS A;  4GTP B;  1QWN A;  3UD1 A;  4D71 A;  1PX3 A;  4JJJ A;  2F6D A;  3T08 A;  3M01 A;  3E73 A;  1N95 B;  3I3B A;  1V7X A;  1LVN A;  1KFG A;  3RX8 A;  2PNC A;  1IVU A;  3BGA A;  2PMV A;  3QT9 A;  3CZS A;  2JJB A;  1IVX A;  2BRP A;  1RWF A;  1XW2 A;  3E1F 1;  3BUB A;  3SDU A;  1SNZ A;  1LTX B;  1FCE A;  3K5T A;  1NS0 A;  3QDE A;  4MMI A;  5IM1 A;  3X41 A;  3E33 B;  1FMI A;  3X17 A;  5A1A A;  2WMI A;  2BBC A;  4D6F A;  5EAU A;  1O1R B;  3BLC A;  2BRW A;  3SX1 A;  2D73 A;  1KZO B;  3P5P A;  1X9D A;  3OB8 A;  3WKF A;  1C82 A;  1FBO A;  2AFA A;  3S4A A;  1WU6 A;  3G6J B;  1DL2 A;  1KSC A;  1O79 A;  1UG9 A;  3G4D A;  1D8E B;  1GA2 A;  1LUR A;  3DX3 A;  1C3D A;  3DCD A;  1V7V A;  2AHG A;  4J5T A;  1SII A;  4D6C A;  4NEI A;  3T33 A;  4D94 A;  3PGB A;  3S4B A;  3E80 A;  3WUX A;  3VD9 A;  3WFA A;  2FUQ A;  3DSV B;  1NSU A;  2JF4 A;  3ANI A;  3BVT A;  4XUV A;  2KXR A;  2WMJ A;  2RDY A;  3EZ8 A;  1JYN A;  2NOJ A;  1R76 A;  1NL4 B;  1QBQ B;  1LF6 A;  5EAT A;  2F0Y B;  3DX2 A;  1N4Q B;  2CWV A;  3ANK A;  4V1R A;  1G9J A;  3E32 B;  3PZ4 B;  4GL3 A;  2G0D A;  1X1I A;  3DPY B;  4M76 A;  2CWT A;  3NBJ A;  3P2C A;  3H2W A;  3OED A;  4D6H A;  3CZJ A;  1D6U A;  3MUY 1;  4KFE A;  2WYI A;  3RX5 A;  1IA6 A;  1HN1 A;  4GTV B;  1YGA A;  3HXC B;  1JZ2 A;  1CLC A;  1HXK A;  3SDR A;  4D4C A;  1EKM A;  3WA2 X;  5KKB A;  3KII A;  3QWT A;  1HCU A;  1MN0 A;  1NSV A;  2WDA A;  3DX4 A;  3M02 A;  2D8L A;  2CIS A;  3CU7 A;  2ALW A;  3BVU A;  4BZG A;  2VN4 A;  1N4S B;  4OZV A;  1V5C A;  3REN A;  4CJ1 A;  1G6I A;  1QX1 A;  2WYH A;  1PX4 A;  2BED B;  3Q7A B;  2WIN B;  1O6H A;  3AMO B;  2Z07 A;  3W5N A;  2EAC A;  1LXK A;  4ZRP A;  1TQV A;  3BUI A;  1EGU A;  1HWW A;  5DGQ A;  1SO0 A;  3SFY B;  3BUQ A;  4UFC A;  5JMD A;  2RGK A;  3OS7 A;  5FOB B;  1N24 A;  1DCE B;  3GZK A;  3M76 A;  3D4Z A;  3BVV A;  3VD7 A;  3M71 A;  3EJQ A;  1F4H A;  1H3B A;  3DSU B;  3VXD A;  1XWQ A;  3K25 A;  4TXT A;  4FNU A;  3TY1 A;  1TNO B;  4FNV A;  3RRS A;  2WW3 A;  3PYB A;  2WY7 A;  4DLQ A;  2YIK A;  1NSZ A;  1W6J A;  2C11 A;  2CFK A;  2HTA A;  4EHM B;  1HZF A;  1W2Z A;  2JKA A;  4FNQ A;  3T2P A;  1QWU A;  1H3A A;  3IAQ A;  3PZ1 B;  3H7L A;  3NFV A;  2W0Q A;  3NJV A;  5JMF A;  2F1A A;  4FUS A;  3EJP A;  3OBA A;  1KSI A;  2EAD A;  1O1T B;  2I07 B;  3CIH A;  5DHI A;  3UD2 A;  1WMN A;  3LVT A;  4D6G A;  1DYU A;  1IS9 A;  3SQC A;  2CQT A;  3CV5 A;  5CZL A;  1TQT A;  1TXK A;  1NXC A;  2Y73 A;  4GTS B;  1IVW A;  1WMO A;  2A8Z A;  1K1W A;  4DOE A;  3E37 B;  4BOK A;  5ILZ A;  2FBA A;  3WIR A;  4D72 A;  4Z4L A;  1YQ2 A;  5IL8 A;  1KZP B;  1RKY A;  3E6U A;  3BVX A;  1FT1 B;  1N7P A;  1L7K A;  1RJO A;  5ILH A;  1N9E A;  1HX9 A;  4ONT A;  1AV4 A;  2F18 A;  3BLB A;  2P0V A;  3Q75 B;  3S9V A;  4D6J A;  1IQX A;  3EU8 A;  1N94 B;  5E1Q A;  1TN8 B;  1N9A B;  1GAI A;  1MMU A;  1DOG A;  1HM3 A;  1JCS B;  4YDO B;  3CZN A;  1US1 A;  3HXF B;  1V7W A;  3IAP A;  1N7R A;  3U7V A;  3MUZ 1;  4ZRQ A;  2OOV A;  1KRE A;  3M73 A;  2XWB B;  3QRY A;  3HXD B;  3QXQ A;  5E2J A;  3X40 A;  1N20 A;  5MEH A;  4BTY A;  1H12 A;  3M74 A;  4GTO B;  4KTP A;  1JZ4 A;  2B39 A;  2F7R A;  3J7H A;  2JKE A;  1HM2 A;  3VD5 A;  3RSY A;  5GY3 A;  2GH4 A;  3OXU A;  1WU4 A;  5GZK A;  2NVP A;  3SAE A;  2AHF A;  1H39 A;  3VD3 A;  1FAE A;  3PMM A;  2BB6 A;  3W7S A;  1NS8 A;  2H6G B;  3H3K A;  3PYA A;  4D6D A;  3BVW A;  3M72 A;  1X1H A;  1J0M A;  3C72 B;  2OOV C;  3W5M A;  3HXE B;  1RW9 A;  1F4A A;  5ILK A;  4LNB B;  1SQC A;  2FYV A;  5FO8 B;  4ZH5 A;  3EJT A;  5FO7 B;  3E30 B;  1JYX A;  2FUZ A;  1KRF A;  1UMP A;  1N4P B;  1CB8 A;  3LZ9 A;  1K72 A;  3BS6 A;  3IMH A;  3E34 B;  2DRS A;  1HXG A;  2V8J A;  1PU4 A;  3D50 A;  1NS2 A;  2R2L B;  1CEM A;  3K11 A;  1X1J A;  4WVA A;  1F9G A;  1L1Y A;  1KWF A;  3A0O A;  4RNL A;  3WA3 A;  4MMH A;  2XQW A;  2XFG A;  2WVZ A;  3T2O A;  2FUT A;  1AVL A;  3EUV B;  2E2T A;  4FNR A;  3BUD A;  5AGD A;  5CA3 A;  1SA4 B;  3WIQ A;  4OZW A;  3WIW A;  3W7T A;  1WZZ A;  2XN0 A;  4F13 A;  1JCQ B;  1RQ5 A;  2RI8 A;  5IL3 A;  1JOV A;  1W6G A;  4GTM B;  4KFD A;  2RI9 A;  3S4D A;  1RWA A;  2WMF A;  3VDC A;  3SXX A;  3X3Z A;  2CG1 A;  4BZF A;  1GXN A;  1W3Y A;  1SIH A;  2CIQ A;  3DYP A;  1R33 A;  3VD4 A;  5C05 A;  4WU0 A;  4WVC A;  1LD7 B;  1NC5 A;  2C10 A;  3S4C A;  4LNV A;  1A2V A;  2H6I B;  2WOF A;  1NSS A;  1TF4 A;  3ANJ A;  3VDB A;  1W4N A;  3D51 A;  3MPH A;  3DDF A;  4E1Y A;  5DGR A;  5GW7 A;  3M7E A;  3I3D A;  1S64 B;  4D4D A;  3AMO A;  3SDQ A;  3DYM A;  1IA7 A;  1GLM A;  3D4Y A;  3HXB B;  3ECQ A;  3WKI A;  1G87 A;  2ZXQ A;  2ZIR B;  1D6Z A;  3QT3 A;  3KSL B;  1NI1 B;  1V5D A;  1IU7 A;  3MV0 1;  1OJN A;  1H35 A;  2IEJ B;  1N22 A;  2ZBL A;  2SQC A;  4BOJ A;  4D6I A;  2F7P A;  4D6E A;  4BZE A;  2WOH A;  3KSQ B;  4YCR A;  1FO3 A;  3EU5 B;  1MMZ A;  4Z4J A;  3D3I A;  1H36 A;  3HIG A;  2WVX A;  1QAL A;  3X42 A;  1W6K A;  3DX1 A;  1SPU A;  3KLS A;  1N1Z A;  4YDE B;  4F10 A;  1HTY A;  2CG0 A;  1NSR A;  5M7Y A;  2ONH A;  1QAF A;  1SA5 B;  3VDA A;  4OK2 A;  4OK4 A;  3DRA B;  1GSZ A;  1NS4 A;  3Q1N A;  2H6F B;  2XN2 A;  1N21 A;  3ACT A;  3D52 A;  3X3Y A;  4EV5 A;  1H14 A;  1XWT A;  2A73 B;  1JZ6 A;  4D1J A;  1LOH A;  3QSP A;  1QAK A;  2WO0 A;  3MV1 1;  3WKG A;  1KSD A;  1TNZ B;  1GXM A;  3VSN A;  2GOX A;  5FO9 B;  1VD5 A;  2E22 A;  1O7D D;  3SDT A;  3KBT C;  2D5J A;  4DI5 A;  3K7X A;  4AYO A;  5IK6 A;  2H6H B;  1F1S A;  2WW0 A;  4EL8 A;  4BZH A;  1L7J A;  4DUW A;  1H3C A;  1OJO A;  2F1B A;  3P5R A;  3DSX B;  4Q2B A;  3DST B;  1NKG A;  3EQA A;  2V8I A;  4GAX A;  3PZ2 B;  4L0G A;  1HMW A;  5JPM B;  1F9D A;  5ILY A;  3WVF A;  1GHQ A;  1GXO A;  1O5M B;  1AVK A;  3Q79 B;  4DOD A;  1W5Z A;  1KKT A;  2WGQ A;  3TF4 A;  3VSM A;  2PN5 A;  3DSS B;  1MMY A;  3N0G A;  3T0U A;  2YFO A;  4KTR A;  4GTQ B;  4L9P B;  4RNQ A;  3PQI A;  2OQE C;  3MI6 A;  4KFF A;  4AQ0 A;  3X3X A;  3M7L A;  1OAC A;  3NBB A;  1H37 A;  3NJX A;  3T0A A;  1FP3 A;  1LXM A;  1N23 A;  1O6R A;  3W7W A;  4D8O A;  2WMI B;  2HTB A;  2XN1 A;  1IVV A;  5KBP A;  1WU5 A;  3KBU C;  3GLY A;  4AYP A;  3N9H A;  3EJS A;  1LD8 B;  1N7O A;  1RWC A;  2XHN A;  2CWU A;  1TU5 A;  2CFD A;  1AGM A;  4GTR B;  1TNY B;  1K1X A;  1JZ7 A;  2WMG A;  1JYW A;  2E24 A;  3EJR A;  5IKA A;  1QQF A;  1HV6 A;  1JCR B;  1FBW A;  2EAE A;  2ONG A;  3M78 A;  4FXG B;  2DRO A;  4MU9 A;  1O1S B;  1HMU A;  2WZS A;  5EAS A;  1JZ5 A;  3AFL A;  3QXF A;  5DHK A;  1LF9 A;  3KQ4 A;  4TF4 A;  4BTW A;  4CE7 A;  4LIX A;  5ILI A;  1OJP A;  3T0B A;  2XWJ B;  2CFG A;  2WMH A;  4ZH1 A;  2WMK A;  3M7C A;  2D1W A;  2WY8 A;  2BRV X;  3D5S A;  4QT9 A;  1N4R B;  3KN4 A;  3SEP A;  3ON6 A;  3ALA A;  1OJM A;  2J5C A;  2VN7 A;  2B4F A;  1D6Y A;  3BUP A;  1G9G A;  2ZIS B;  3MWX A;  2WVY A;  3A3V A;  3RJ3 A;  1JRQ A;  1J0N A;  1N1B A;  1RWH A;  3G4F A;  3T2Q A;  1X81 B;  2YX9 A;  1TQU A;  2WW1 A;  2X03 A;  4TTG A;  5CD2 A;  2V8K A;  1KS8 A;  3Q73 B;  2F7Q A;  3QG0 A;  5ILJ A;  4OJZ A;  1UT9 A;  5IKH A;  1Z45 A;  1H13 A;  3D5R A;  4GTT B;  3QFY A;  4V1S A;  4DUX A;  1F9O A;  2ZZR A;  5IK0 A;  2KXS A;  1JZ3 A;  1N7N A;  2V3N A;  2WII B;  3QPF A;  1DP0 A;  1S63 B;  2EAB A;  2F7O A;  1JS4 A;  2JG0 A;  3DDG A;  4Q88 A;  2YFN A;  1FPP B;  2GZ6 A;  2WCO A;  2WW2 A;  1K1Y A;  2ZQ0 A;  3HII A;  2FV1 A;  3HI7 A;  2E2V A;  3PZ3 B;  1TN7 B;  1AYX A;  4FNP A;  1W7C A;  1ULV A;  2OW6 A;  2Y74 A;  1JYV A;  3T09 A;  2BB5 A;  1W6C A;  1QAZ A;  3Q78 B;  1TN6 B;  3DSW B;  2G02 A;  4L6X A;  3VW5 A;  1NS7 A;  3M00 A;  4K35 A;  3LOY A;  3SFX B;  3N0F A;  2CFW A;  3A24 A;  2QNO A;  5ILD A;  4D1I A;  3NRE A;  1H54 A;  3Q7F B;  4AYR A;  5JPN B;  1JZ8 A;  1WMP A;  1NSM A;  1I8Q A;  3EJU A;  5IK9 A;  4FJQ A;  1PS3 A;  3I3E A;  3F59 A;  2BT3 A;  2ZL8 A;  3QFZ A;  1L2A A;  2DRQ A;  3NNB A;  2CFL A;  2WVX B;  4D4B A;  1D8D B;  2Q1F A;  3RX7 A;  3QR8 A;  4DLO A;  1NSX A;  1N7Q A;  1QSJ A;  1O6Q A;  3T0D A; 
#chains in the Genus database with same CATH homology
 4AQ0 A;  1NS2 A;  3E7J A;  1EGU A;  1RWG A;  1X1J A;  3NJX A;  3T0A A;  1F9G A;  1LXM A;  3A0O A;  1SO0 A;  4RNL A;  4MMH A;  5JMD A;  3T2O A;  2CIR A;  2WMI B;  2HTB A;  1HN0 A;  2FUT A;  2WVZ A;  3OS7 A;  4DUV A;  2JKP A;  3VD7 A;  1N7O A;  1RWC A;  4OZW A;  2XHN A;  2XSG A;  1JZ7 A;  1F4H A;  1K1X A;  4F13 A;  2WMG A;  1JYW A;  1JOV A;  2E24 A;  3K25 A;  3DYO A;  3TY1 A;  1RWA A;  2WMF A;  3VDC A;  4FNV A;  1HV6 A;  4BZF A;  2WW3 A;  1W3Y A;  2CIQ A;  3DYP A;  3VD4 A;  1NSZ A;  2HTA A;  1HMU A;  1MMX A;  2WZS A;  3DEC A;  1JZ5 A;  3AFL A;  2JKA A;  3T2P A;  1LF9 A;  4D71 A;  1PX3 A;  1NSS A;  3IAQ A;  3T08 A;  1OJP A;  3VDB A;  3NFV A;  3T0B A;  3NJV A;  5JMF A;  2WMH A;  3I3B A;  2WMK A;  4E1Y A;  3OBA A;  2BRV X;  3BGA A;  3SEP A;  3I3D A;  4D6G A;  1OJM A;  3MWX A;  2BRP A;  2WVY A;  1RWF A;  1TXK A;  3DYM A;  3E1F 1;  1J0N A;  3ECQ A;  1SNZ A;  1RWH A;  1K1W A;  3T2Q A;  1NS0 A;  4MMI A;  2X03 A;  2WW1 A;  2ZXQ A;  4TTG A;  5A1A A;  2WMI A;  4D72 A;  4D6F A;  1YQ2 A;  3MV0 1;  1OJN A;  3BLC A;  4OJZ A;  2BRW A;  1N7P A;  1L7K A;  2D73 A;  1Z45 A;  3OB8 A;  4D6I A;  1C82 A;  4D6E A;  4DUX A;  4BZE A;  4D6J A;  1JZ3 A;  1N7N A;  1DP0 A;  1UG9 A;  1MMZ A;  5E1Q A;  1LUR A;  2WVX A;  1MMU A;  1HM3 A;  3DCD A;  4J5T A;  4D6C A;  4NEI A;  2WCO A;  4F10 A;  2WW2 A;  1K1Y A;  2ZQ0 A;  3E80 A;  3VD9 A;  3IAP A;  3MUZ 1;  1N7R A;  1NSR A;  3WFA A;  2FUQ A;  1NSU A;  1ULV A;  1JYV A;  3VDA A;  4OK2 A;  4OK4 A;  3T09 A;  2WMJ A;  1NS4 A;  3Q1N A;  1JZ4 A;  1JYN A;  3J7H A;  1QAZ A;  1LF6 A;  2JKE A;  1HM2 A;  3VD5 A;  1JZ6 A;  1NS7 A;  1LOH A;  3MV1 1;  3A24 A;  1X1I A;  3VSN A;  3VD3 A;  3NRE A;  2E22 A;  4D6H A;  3CZJ A;  3MUY 1;  1NS8 A;  1JZ8 A;  4D6D A;  1F1S A;  1HN1 A;  2WW0 A;  1X1H A;  4BZH A;  1L7J A;  1I8Q A;  1OJO A;  1J0M A;  1NSM A;  1YGA A;  3I3E A;  4DUW A;  1JZ2 A;  3T0D A;  1RW9 A;  1F4A A;  1NKG A;  1HMW A;  1MN0 A;  1NSV A;  2WDA A;  3WVF A;  3NNB A;  2CIS A;  4BZG A;  2WVX B;  1JYX A;  4OZV A;  2Q1F A;  1NSX A;  1CB8 A;  1N7Q A;  1PX4 A;  3VSM A;  1MMY A;  3BS6 A;  3IMH A;  1LXK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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