2BRVX

Crystal structure of streptococcus pneumoniae hyaluronate lyase from 70percent saturated malonate.
Total Genus 192
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
722
structure length
714
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSILWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 192
structure length 714
sequence length 722
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2005-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
X PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
X PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2brvX01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2brvX03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2brvX02
3T0BA 3DYOA 3DCDA 3MV11 1W3YA 1N7OA 3MUZ1 2WW1A 3IAPA 5JMDA 4RNLA 1JOVA 3VSNA 4F13A 1NSXA 1OJMA 2WMIA 3VD4A 1F4HA 1YQ2A 3MWXA 3BGAA 3T2PA 3T0DA 2WMGA 1HMUA 3VD5A 2X03A 3OB8A 1JZ8A 4BZEA 1DP0A 1MMZA 3OBAA 1QAZA 1JYVA 2E24A 2WMHA 2WVZA 2WW3A 3WFAA 1F9GA 1X1IA 1F1SA 1NSRA 1N7RA 1NS0A 2XHNA 3DECA 2WMFA 1JZ2A 1LOHA 4D6DA 1LXKA 3VD9A 2CIQA 4AQ0A 1K1XA 2ZXQA 1NSMA 5A1AA 4D6HA 4NEIA 3NJXA 2HTAA 1JZ6A 2BRPA 1NS7A 1CB8A 1X1JA 1PX4A 3MUY1 2Q1FA 2WVXB 2WVYA 5E1QA 3SEPA 1JZ4A 1MMUA 1PX3A 1N7QA 1SO0A 1N7PA 3I3EA 2BRVX 4MMHA 3IMHA 1NS8A 1JYNA 2WVXA 3AFLA 1NKGA 4D6JA 1NS4A 3E80A 1OJNA 1K1YA 1MN0A 5JMFA 3J7HA 3OS7A 1N7NA 4D6IA 1MMXA 3T2OA 2JKEA 1F4AA 3E7JA 4FNVA 2BRWA 3A24A 4DUVA 3VD7A 1J0NA 2HTBA 4BZGA 4D6FA 3E1F1 1OJPA 3A0OA 1NSUA 1UG9A 4D6GA 4D6EA 2WZSA 3MV01 1JYXA 4OJZA 3VD3A 1JZ5A 4D6CA 1L7JA 3T08A 1C82A 3VDBA 1HN1A 1LXMA 4BZFA 3Q1NA 3K25A 1NSVA 4MMIA 4E1YA 1HN0A 1LF6A 2FUTA 1Z45A 1YGAA 1LF9A 3ECQA 3IAQA 4OZWA 1K1WA 3NJVA 1RWAA 1RWFA 2CISA 2WW0A 2WW2A 3T09A 3VSMA 1NS2A 2D73A 2WMJA 1JZ7A 3NREA 1JZ3A 1LURA 3NNBA 2WMIB 3VDAA 1SNZA 4OZVA 1ULVA 4OK2A 1NSSA 1I8QA 4DUWA 2E22A 2XSGA 1L7KA 1NSZA 1HM2A 1HM3A 3T0AA 2WCOA 1JYWA 1RWCA 2CIRA 4DUXA 1OJOA 1MMYA 1X1HA 4OK4A 2JKAA 4TTGA 2JKPA 1RWHA 4D72A 1RWGA 4BZHA 3DYPA 1HMWA 3DYMA 2WMKA 4F10A 3VDCA 3I3DA 3CZJA 2FUQA 2WDAA 1J0MA 3NFVA 2ZQ0A 1HV6A 1RW9A 4D71A 1TXKA 3I3BA 3T2QA 1EGUA
chains in the Genus database with same CATH superfamily
5EAUA 4WU0A 1LD8B 3DCDA 1W3YA 3K5TA 3OXUA 2WW1A 1S63B 1QBQB 2FV0A 3M72A 4KKIA 3W7UA 2I07B 2WIIB 1F4HA 3D4ZA 3BVXA 3EJSA 4BTXA 2R2LB 3BVWA 3X17A 3T0UA 2IEJB 2WMGA 3CU7A 1O1TB 1O79A 2W0QA 3SX1A 1JZ8A 1DP0A 4D1IA 1MMZA 2F7OA 1QAZA 2F7PA 1N7RA 2G02A 2XQWA 3EUVB 4AYRA 5ILJA 1IQXA 1O6QA 1N9AB 1SA4B 2WMFA 5ILDA 3EQAA 1GHQA 2OW6A 2ZZRA 3KIIA 2F0YB 1RJOA 3BUQA 3G4FA 2V8IA 4D6HA 3Q79B 1HTYA 1JZ6A 4D4AA 1H13A 3WIWA 3QT9A 2CFWA 1WU6A 1WU4A 1C3DA 1JZ4A 2Z07A 1KSIA 1PX3A 3KSQB 3QT3A 5IM1A 1DOGA 2BRVX 2CWUA 5IL8A 4EV5A 4FXGB 1NKGA 3HXBB 4GL3A 2NVPA 3E80A 3OS7A 3D4YA 1MMXA 2OQEC 1IU7A 3CV5A 5MEHA 3Q7AB 3SDQA 2AHFA 2YX9A 3PGBA 3M77A 3UD1A 1HXGA 2ZISB 1O5MB 3RENA 1KZPB 2A8ZA 1US1A 3HXFB 5DHIA 1QWUA 1FMIA 3E37B 3EZ8A 3SDVA 1LD7B 1H37A 1QAKA 1X9DA 4FXKB 3K25A 2J5CA 1TN8B 2FUTA 1SA5B 1Z45A 1TQSA 3NJVA 4L0GA 3Q7FB 1K1WA 3VD7A 4DI5A 3VSMA 5IKHA 3X3YA 5CD2A 3MPHA 3M74A 4GTRB 3S4CA 1X81B 3AMOA 2WMIB 3ANKA 1ULVA 2G0DA 1DCEB 5JPNB 1NSSA 1UMPA 2E22A 2XSGA 1MZCB 2B39A 2ONGA 2KXSA 4BTWA 3X3XA 4V1RA 4V1SA 1QALA 2E2VA 2F7QA 4OK4A 2KXRA 3EJQA 1W6CA 1NL4B 3N9HA 4BTYA 3CIHA 3DSXB 1FO2A 3BLBA 2WGQA 5AGDA 2JKPA 4BZHA 1RWGA 3HXDB 3DYPA 4BOJA 5DHKA 4F10A 1TF4A 3DSSB 3N0GA 1G9GA 3RJ3A 3RX8A 3M75A 3PMMA 3QFYA 3D3IA 3KSLB 1J0MA 1TNZB 4GTPB 1L2AA 3HIIA 1RW9A 4D71A 1TXKA 3HIGA 3WFAA 1N4PB 2BEDB 2OOVA 3ANIA 1XWTA 2CFLA 1A2VA 2V3PA 3DYOA 2WYIA 1IVVA 5C05A 2V8JA 4D94A 3NBBA 3MUZ1 3IAPA 4RNLA 4AYQA 1H3CA 1G87A 3VSNA 1NSXA 2H6GB 1TQVA 4WVAA 1YQ2A 3PZ4B 3T2PA 2BT3A 5GZKA 3DX2A 3H3KA 3M7LA 5IK0A 4C1SA 4DOEA 5FO8B 3ON6A 2E24A 1JRQA 1X1IA 1F1SA 1N4SB 2RI9A 4LNGB 3DX0A 3DECA 1V5DA 3BVUA 1RKYA 3RX7A 4LNVA 2CIQA 5IL3A 4AQ0A 3A3VA 3X41A 4NEIA 1GA2A 1R34A 1CB8A 1X1JA 2H6FB 1PX4A 2E2TA 1R33A 5E1QA 3SEPA 1KFGA 2AHGA 4GTMB 2CFDA 3S4AA 1AYXA 1W7CA 1FAEA 1V7XA 3IMHA 2Y73A 3AFLA 2E2UA 4D6JA 1NS4A 3RRSA 3QWTA 2DRSA 2EAEA 1OJNA 1K1YA 1SIHA 4GTSB 2WOFA 2XFGA 3M7CA 4GTTB 1N4RB 4D6IA 1UI8A 3BS6A 3T2OA 1D8EB 5FO7B 1WMPA 3E7JA 1W6KA 3GLYA 1IVUA 2FUZA 3D51A 3WIRA 3A24A 3WA3A 4DODA 3C72B 1H14A 1J0NA 1JCQB 2WYNA 4BZGA 1HXCA 3KQ4A 3DX4A 1V5CA 5KBPA 1OJPA 1NSUA 3WKIA 3W5NA 3X42A 3G4DA 2WZSA 2F1AA 4OJZA 4J5TA 2JJBA 3CZNA 1JZ5A 1KKTA 1L7JA 5GY3A 3EJTA 2NOJA 4FNRA 3EU5B 1JCSB 1AV4A 2BB6A 4QT9A 2SQCA 4DLQA 1QX1A 3RX5A 3SXXA 3H7LA 4MMIA 4YCRA 2VN4A 1HWWA 3BLCA 3ECQA 1DL2A 1RWFA 1QSJA 5ILYA 2WW2A 1N9EA 1SIIA 1NS2A 2D73A 4RNQA 3NREA 1PU4A 2ZBLA 1LURA 1RQ5A 2CG1A 3D5SA 2RDYA 3DX1A 1IA6A 1TNOB 2PMVA 4AYOA 2YFNA 3M76A 3M78A 1PS3A 1NSZA 1HM2A 1L1YA 2CWVA 2OOVC 4UFCA 1FO3A 1NC5A 3T0AA 3DRAB 4ZH5A 3KLSA 3DSTB 1OJOA 2D1WA 5GW7A 2WINB 3ANJA 2JKAA 1IS9A 3PZ1B 2XN1A 4CE7A 1NXCA 2V8KA 1W2ZA 1HMWA 1FP3A 2WMKA 1WU5A 1W5ZA 1G9JA 1H54A 1UT9A 2PNCA 5ILKA 2WDAA 1W4NA 5DGRA 2ZQ0A 5FO9B 3T33A 1TN6B 3W7WA 1N21A 5JPMB 3BUPA 1TQWA 3T2QA 1KWFA 3BUIA 2DRQA 1O1SB 3SQCA 3P5PA 2CWTA 1CLCA 3T0BA 3M00A 4KFFA 1N94B 3DSVB 3E6UA 5CA3A 3K7XA 1OJMA 2WMIA 1GXMA 2EACA 3M7BA 3ACSA 1O1RB 3PYAA 3WKFA 1FT2B 1R76A 5KKBA 5M7IA 2RGKA 3D52A 2DROA 3MWXA 1V7WA 1O7DD 4GTVB 3VD5A 2X03A 3OB8A 2H6HB 3P5RA 3W7SA 3E30B 3ALAA 1GXNA 4FNTA 1JYVA 2F7RA 2F6DA 1HX9A 3QPFA 4TXTA 3KBTC 2WY7A 2WVZA 1F9GA 1LTXB 4Z4JA 2VN7A 1FBOA 1GXOA 4D6DA 1N1ZA 3VD9A 3QDEA 1CEMA 1XWQA 2XN0A 2ZL8A 3PQIA 3LZ9A 1GAHA 1KSDA 3NJXA 3PZ2B 1V7VA 4DLOA 5IK9A 2AFAA 5ILZA 5IK6A 2Q1FA 4BOKA 1H36A 1AVKA 2WVXB 2WVYA 3BVVA 4ZH1A 2PN5A 1NI1B 1D6UA 3WIQA 2EADA 3H2WA 3WC3A 1N7QA 4KTPA 2WO0A 1JYNA 2WVXA 1FPPB 5E2JA 1MN0A 5JMFA 2C11A 1N7NA 2V3NA 2BBCA 2BB5A 5DGQA 3M71A 3GZKA 3RSYA 3G6JB 3WUXA 2BRWA 1TNUB 3SDRA 5ILIA 1G6IA 2HTBA 4D6FA 3E1F1 3K11A 3A0OA 1UG9A 3MV01 1N1BA 3VW5A 2FYVA 2D5JA 3WKGA 3SFYB 3DDFA 3X3ZA 3QXQA 4D1JA 4D6CA 3M73A 3T08A 1C82A 3VDBA 2A73B 3QSPA 5CZLA 1FCEA 3HXCB 4EL8A 1HXAA 1N23A 3Q1NA 4BZFA 1HN0A 1LF6A 2FV1A 1SPUA 3Q75B 1LF9A 3T09A 4OZWA 1RWAA 3VD3A 2CISA 2CQTA 2WW0A 1TQTA 4MBGB 3WVFA 3W7XA 3P2CA 1O6RA 1H35A 4L9PB 3CZSA 4CJ1A 4EHMB 1N20A 3QXFA 2WOHA 1SNZA 1WMOA 4OZVA 4OK2A 3MI6A 2CG0A 1AGMA 1D6ZA 1L7KA 1HZFA 2WCOA 1QQFA 4Q88A 1RWCA 3QRYA 4KKJA 2CIRA 1MMYA 2QNOA 4GAXA 4TTGA 4D8OA 2XWJB 4D72A 1VD5A 4KFEA 2H6IB 4WVCA 2P0VA 3DYMA 2EABA 3VDCA 5FOBB 1XW2A 3BUBA 1GLMA 3HI7A 3I3DA 4M76A 3WA2X 1WMNA 1TNBB 2FUQA 1DYUA 3DPYB 3OEDA 2GH4A 3NFVA 4MU9A 1IQYA 1HV6A 1KZOB 1GSZA 3S9VA 4BZEA 3EJRA 1KS8A 1EGUA 1F9DA 3MV11 1GAIA 1N7OA 2CFGA 4YDOB 3TY1A 1EKMA 5JMDA 1AVLA 1JOVA 4FNSA 3E32B 4F13A 3VD4A 4ONTA 2ZIRB 4YDEB 4FNUA 1N4QB 3BGAA 1QAFA 3T0DA 4JJJA 1HMUA 1HCUA 3N0FA 3OBAA 1SQCA 2FBAA 4ZG8A 3U7VA 3QFZA 4XUVA 2WMHA 2WW3A 5EATA 1NSRA 1TQUA 3SAEA 1NS0A 4L6XA 1H12A 1KREA 2XHNA 3WKHA 2CFKA 1JZ2A 1F9OA 1LOHA 1LXKA 1O6HA 2OW7A 1K1XA 2ZXQA 1NSMA 1D8DB 2B4FA 1FT1B 3QG0A 4AYPA 2BRPA 1NS7A 2HTAA 2F18A 3SDUA 3MUY1 1HXKA 1JS4A 1QWNA 1KRFA 3QR8A 1KSCA 3SDTA 3SFXB 1MMUA 1H3AA 1N24A 3E73A 5EASA 3BVTA 1TU5A 1IA7A 4KTRA 3BUDA 1SO0A 1N7PA 3I3EA 3M7EA 4MMHA 3AMOB 1LVNA 1NS8A 2CQSA 1WZZA 3J7HA 3W7TA 2ONHA 2Y74A 4TF4A 2ALWA 4FJQA 2DRRA 3EJUA 2JKEA 1F4AA 3AFJA 4GTOB 4D4CA 3W5MA 4FNQA 2C10A 4FNVA 3PYBA 4DUVA 3D50A 3F59A 2GOXA 2JG0A 4KFDA 3DSWB 3HXEB 3PZ3B 4D6GA 1IVWA 4D6EA 2WYHA 1JYXA 4Q2BA 1TN7B 1W6JA 4FNPA 3S4BA 2JF4A 3E33B 3KBUC 3DX3A 1HN1A 1LXMA 3DDGA 3EU8A 3ACTA 1H3BA 3Q73B 2RI8A 3Q78B 1NSVA 4E1YA 2OQEA 1YGAA 3DSUB 4D4BA 1W6GA 3IAQA 3EJPA 1JZ7A 2WMJA 1UI7A 2XN2A 4WVBA 1K72A 1JZ3A 1OACA 3NNBA 4Z4LA 4EV2A 2XWBB 2WY8A 1IVXA 3VDAA 3KN4A 2OKXA 3GT5A 1I8QA 1TNYB 4DUWA 2F1BA 5IKAA 1HM3A 1JYWA 3UD2A 4ZRPA 4DUXA 2YIKA 4K3AA 1N95B 1X1HA 4ZRQA 1D6YA 3VXDA 2YFOA 3X40A 1RWHA 2D8LA 4D4DA 1H39A 3LVTA 5ILHA 3LOYA 1S64B 4FUSA 3TF4A 1FBWA 1JCRB 4LNBB 5A1AA 2GZ6A 3CZJA 3NBJA 4CJ0A 5M7YA 3D5RA 3E34B 3S4DA 4K35A 3M01A 3M02A 1N22A 3I3BA 4LIXA 4GTQB
chains in the Genus database with same CATH topology
3T0BA 3DYOA 3DCDA 3MV11 1W3YA 1N7OA 3MUZ1 3TY1A 2WW1A 3IAPA 5JMDA 4RNLA 1JOVA 3VSNA 4F13A 1NSXA 1OJMA 2WMIA 3VD4A 1F4HA 1YQ2A 3MWXA 3BGAA 3T2PA 3T0DA 2WMGA 1HMUA 3VD5A 2X03A 3OB8A 1JZ8A 4BZEA 1DP0A 1MMZA 3OBAA 1QAZA 1JYVA 2E24A 2WMHA 2WVZA 2WW3A 3WFAA 1F9GA 1X1IA 1F1SA 1NSRA 1N7RA 1NS0A 2XHNA 3DECA 2WMFA 1JZ2A 1LOHA 4D6DA 1LXKA 3VD9A 2CIQA 4AQ0A 1K1XA 2ZXQA 1NSMA 5A1AA 4D6HA 4NEIA 3NJXA 2HTAA 1JZ6A 2BRPA 1NS7A 1CB8A 1X1JA 1PX4A 3MUY1 2Q1FA 2WVXB 2WVYA 5E1QA 3SEPA 1JZ4A 1MMUA 1PX3A 1N7QA 1SO0A 1N7PA 3I3EA 2BRVX 4MMHA 3IMHA 1NS8A 1JYNA 2WVXA 3AFLA 1NKGA 4D6JA 1NS4A 3E80A 1OJNA 1K1YA 1MN0A 5JMFA 3J7HA 3OS7A 1N7NA 4D6IA 1MMXA 3BS6A 3NJVA 3T2OA 2JKEA 1F4AA 3E7JA 4FNVA 2BRWA 3A24A 4DUVA 3VD7A 1J0NA 2HTBA 4BZGA 4D6FA 3E1F1 1OJPA 3A0OA 1NSUA 1UG9A 4D6GA 4D6EA 2WZSA 3MV01 1JYXA 4OJZA 4J5TA 3VD3A 1JZ5A 4D6CA 1L7JA 3T08A 1C82A 3VDBA 1HN1A 1LXMA 4BZFA 3Q1NA 3K25A 1NSVA 4MMIA 4E1YA 1HN0A 1LF6A 2FUTA 1Z45A 1YGAA 1LF9A 3BLCA 3ECQA 4OZWA 1K1WA 3IAQA 1RWAA 1RWFA 2CISA 2WW0A 2WW2A 3T09A 3VSMA 1NS2A 2D73A 2WMJA 3WVFA 1JZ7A 3NREA 1JZ3A 1LURA 3NNBA 2WMIB 3VDAA 1SNZA 4OZVA 1ULVA 4OK2A 1NSSA 1I8QA 4DUWA 2E22A 2XSGA 1L7KA 1NSZA 1HM2A 1HM3A 3T0AA 2WCOA 1JYWA 1RWCA 2CIRA 4DUXA 1OJOA 1MMYA 1X1HA 4OK4A 2JKAA 4TTGA 2JKPA 1RWHA 4D72A 1RWGA 4BZHA 3DYPA 1HMWA 3DYMA 2WMKA 4F10A 3VDCA 3I3DA 3CZJA 2FUQA 2WDAA 1J0MA 3NFVA 2ZQ0A 1HV6A 1RW9A 4D71A 1TXKA 3I3BA 3T2QA 1EGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T0B A;  3DYO A;  3DCD A;  3MV1 1;  1W3Y A;  1N7O A;  3MUZ 1;  2WW1 A;  3IAP A;  5JMD A;  4RNL A;  1JOV A;  3VSN A;  4F13 A;  1NSX A;  1OJM A;  2WMI A;  3VD4 A;  1F4H A;  1YQ2 A;  3MWX A;  3BGA A;  3T2P A;  3T0D A;  2WMG A;  1HMU A;  3VD5 A;  2X03 A;  3OB8 A;  1JZ8 A;  4BZE A;  1DP0 A;  1MMZ A;  3OBA A;  1QAZ A;  1JYV A;  2E24 A;  2WMH A;  2WVZ A;  2WW3 A;  3WFA A;  1F9G A;  1X1I A;  1F1S A;  1NSR A;  1N7R A;  1NS0 A;  2XHN A;  3DEC A;  2WMF A;  1JZ2 A;  1LOH A;  4D6D A;  1LXK A;  3VD9 A;  2CIQ A;  4AQ0 A;  1K1X A;  2ZXQ A;  1NSM A;  5A1A A;  4D6H A;  4NEI A;  3NJX A;  2HTA A;  1JZ6 A;  2BRP A;  1NS7 A;  1CB8 A;  1X1J A;  1PX4 A;  3MUY 1;  2Q1F A;  2WVX B;  2WVY A;  5E1Q A;  3SEP A;  1JZ4 A;  1MMU A;  1PX3 A;  1N7Q A;  1SO0 A;  1N7P A;  3I3E A;  2BRV X;  4MMH A;  3IMH A;  1NS8 A;  1JYN A;  2WVX A;  3AFL A;  1NKG A;  4D6J A;  1NS4 A;  3E80 A;  1OJN A;  1K1Y A;  1MN0 A;  5JMF A;  3J7H A;  3OS7 A;  1N7N A;  4D6I A;  1MMX A;  3T2O A;  2JKE A;  1F4A A;  3E7J A;  4FNV A;  2BRW A;  3A24 A;  4DUV A;  3VD7 A;  1J0N A;  2HTB A;  4BZG A;  4D6F A;  3E1F 1;  1OJP A;  3A0O A;  1NSU A;  1UG9 A;  4D6G A;  4D6E A;  2WZS A;  3MV0 1;  1JYX A;  4OJZ A;  3VD3 A;  1JZ5 A;  4D6C A;  1L7J A;  3T08 A;  1C82 A;  3VDB A;  1HN1 A;  1LXM A;  4BZF A;  3Q1N A;  3K25 A;  1NSV A;  4MMI A;  4E1Y A;  1HN0 A;  1LF6 A;  2FUT A;  1Z45 A;  1YGA A;  1LF9 A;  3ECQ A;  3IAQ A;  4OZW A;  1K1W A;  3NJV A;  1RWA A;  1RWF A;  2CIS A;  2WW0 A;  2WW2 A;  3T09 A;  3VSM A;  1NS2 A;  2D73 A;  2WMJ A;  1JZ7 A;  3NRE A;  1JZ3 A;  1LUR A;  3NNB A;  2WMI B;  3VDA A;  1SNZ A;  4OZV A;  1ULV A;  4OK2 A;  1NSS A;  1I8Q A;  4DUW A;  2E22 A;  2XSG A;  1L7K A;  1NSZ A;  1HM2 A;  1HM3 A;  3T0A A;  2WCO A;  1JYW A;  1RWC A;  2CIR A;  4DUX A;  1OJO A;  1MMY A;  1X1H A;  4OK4 A;  2JKA A;  4TTG A;  2JKP A;  1RWH A;  4D72 A;  1RWG A;  4BZH A;  3DYP A;  1HMW A;  3DYM A;  2WMK A;  4F10 A;  3VDC A;  3I3D A;  3CZJ A;  2FUQ A;  2WDA A;  1J0M A;  3NFV A;  2ZQ0 A;  1HV6 A;  1RW9 A;  4D71 A;  1TXK A;  3I3B A;  3T2Q A;  1EGU A; 
#chains in the Genus database with same CATH topology
 5EAU A;  4WU0 A;  1LD8 B;  3DCD A;  1W3Y A;  3K5T A;  3OXU A;  2WW1 A;  1S63 B;  1QBQ B;  2FV0 A;  3M72 A;  4KKI A;  3W7U A;  2I07 B;  2WII B;  1F4H A;  3D4Z A;  3BVX A;  3EJS A;  4BTX A;  2R2L B;  3BVW A;  3X17 A;  3T0U A;  2IEJ B;  2WMG A;  3CU7 A;  1O1T B;  1O79 A;  2W0Q A;  3SX1 A;  1JZ8 A;  1DP0 A;  4D1I A;  1MMZ A;  2F7O A;  1QAZ A;  2F7P A;  1N7R A;  2G02 A;  2XQW A;  3EUV B;  4AYR A;  5ILJ A;  1IQX A;  1O6Q A;  1N9A B;  1SA4 B;  2WMF A;  5ILD A;  3EQA A;  1GHQ A;  2OW6 A;  2ZZR A;  3KII A;  2F0Y B;  1RJO A;  3BUQ A;  3G4F A;  2V8I A;  4D6H A;  3Q79 B;  1HTY A;  1JZ6 A;  4D4A A;  1H13 A;  3WIW A;  3QT9 A;  2CFW A;  1WU6 A;  1WU4 A;  1C3D A;  1JZ4 A;  2Z07 A;  1KSI A;  1PX3 A;  3KSQ B;  3QT3 A;  5IM1 A;  1DOG A;  2BRV X;  2CWU A;  5IL8 A;  4EV5 A;  4FXG B;  1NKG A;  3HXB B;  4GL3 A;  2NVP A;  3E80 A;  3OS7 A;  3D4Y A;  1MMX A;  2OQE C;  1IU7 A;  3CV5 A;  5MEH A;  3Q7A B;  3SDQ A;  2AHF A;  2YX9 A;  3PGB A;  3M77 A;  3UD1 A;  1HXG A;  2ZIS B;  1O5M B;  3REN A;  1KZP B;  2A8Z A;  1US1 A;  3HXF B;  5DHI A;  1QWU A;  1FMI A;  3E37 B;  3EZ8 A;  3SDV A;  1LD7 B;  1H37 A;  1QAK A;  1X9D A;  4FXK B;  3K25 A;  2J5C A;  1TN8 B;  2FUT A;  1SA5 B;  1Z45 A;  1TQS A;  3NJV A;  4L0G A;  3Q7F B;  1K1W A;  3VD7 A;  4DI5 A;  3VSM A;  5IKH A;  3X3Y A;  5CD2 A;  3MPH A;  3M74 A;  4GTR B;  3S4C A;  1X81 B;  3AMO A;  2WMI B;  3ANK A;  1ULV A;  2G0D A;  1DCE B;  5JPN B;  1NSS A;  1UMP A;  2E22 A;  2XSG A;  1MZC B;  2B39 A;  2ONG A;  2KXS A;  4BTW A;  3X3X A;  4V1R A;  4V1S A;  1QAL A;  2E2V A;  2F7Q A;  4OK4 A;  2KXR A;  3EJQ A;  1W6C A;  1NL4 B;  3N9H A;  4BTY A;  3CIH A;  3DSX B;  1FO2 A;  3BLB A;  2WGQ A;  5AGD A;  2JKP A;  4BZH A;  1RWG A;  3HXD B;  3DYP A;  4BOJ A;  5DHK A;  4F10 A;  1TF4 A;  3DSS B;  3N0G A;  1G9G A;  3RJ3 A;  3RX8 A;  3M75 A;  3PMM A;  3QFY A;  3D3I A;  3KSL B;  1J0M A;  1TNZ B;  4GTP B;  1L2A A;  3HII A;  1RW9 A;  4D71 A;  1TXK A;  3HIG A;  3WFA A;  1N4P B;  2BED B;  2OOV A;  3ANI A;  1XWT A;  2CFL A;  1A2V A;  2V3P A;  3DYO A;  2WYI A;  1IVV A;  5C05 A;  2V8J A;  4D94 A;  3NBB A;  3MUZ 1;  3IAP A;  4RNL A;  4AYQ A;  1H3C A;  1G87 A;  3VSN A;  1NSX A;  2H6G B;  1TQV A;  4WVA A;  1YQ2 A;  3PZ4 B;  3T2P A;  2BT3 A;  5GZK A;  3DX2 A;  3H3K A;  3M7L A;  5IK0 A;  4C1S A;  4DOE A;  5FO8 B;  3ON6 A;  2E24 A;  1JRQ A;  1X1I A;  1F1S A;  1N4S B;  2RI9 A;  4LNG B;  3DX0 A;  3DEC A;  1V5D A;  3BVU A;  1RKY A;  3RX7 A;  4LNV A;  2CIQ A;  5IL3 A;  4AQ0 A;  3A3V A;  3X41 A;  4NEI A;  1GA2 A;  1R34 A;  1CB8 A;  1X1J A;  2H6F B;  1PX4 A;  2E2T A;  1R33 A;  5E1Q A;  3SEP A;  1KFG A;  2AHG A;  4GTM B;  2CFD A;  3S4A A;  1AYX A;  1W7C A;  1FAE A;  1V7X A;  3IMH A;  2Y73 A;  3AFL A;  2E2U A;  4D6J A;  1NS4 A;  3RRS A;  3QWT A;  2DRS A;  2EAE A;  1OJN A;  1K1Y A;  1SIH A;  4GTS B;  2WOF A;  2XFG A;  3M7C A;  4GTT B;  1N4R B;  4D6I A;  1UI8 A;  3BS6 A;  3T2O A;  1D8E B;  5FO7 B;  1WMP A;  3E7J A;  1W6K A;  3GLY A;  1IVU A;  2FUZ A;  3D51 A;  3WIR A;  3A24 A;  3WA3 A;  4DOD A;  3C72 B;  1H14 A;  1J0N A;  1JCQ B;  2WYN A;  4BZG A;  1HXC A;  3KQ4 A;  3DX4 A;  1V5C A;  5KBP A;  1OJP A;  1NSU A;  3WKI A;  3W5N A;  3X42 A;  3G4D A;  2WZS A;  2F1A A;  4OJZ A;  4J5T A;  2JJB A;  3CZN A;  1JZ5 A;  1KKT A;  1L7J A;  5GY3 A;  3EJT A;  2NOJ A;  4FNR A;  3EU5 B;  1JCS B;  1AV4 A;  2BB6 A;  4QT9 A;  2SQC A;  4DLQ A;  1QX1 A;  3RX5 A;  3SXX A;  3H7L A;  4MMI A;  4YCR A;  2VN4 A;  1HWW A;  3BLC A;  3ECQ A;  1DL2 A;  1RWF A;  1QSJ A;  5ILY A;  2WW2 A;  1N9E A;  1SII A;  1NS2 A;  2D73 A;  4RNQ A;  3NRE A;  1PU4 A;  2ZBL A;  1LUR A;  1RQ5 A;  2CG1 A;  3D5S A;  2RDY A;  3DX1 A;  1IA6 A;  1TNO B;  2PMV A;  4AYO A;  2YFN A;  3M76 A;  3M78 A;  1PS3 A;  1NSZ A;  1HM2 A;  1L1Y A;  2CWV A;  2OOV C;  4UFC A;  1FO3 A;  1NC5 A;  3T0A A;  3DRA B;  4ZH5 A;  3KLS A;  3DST B;  1OJO A;  2D1W A;  5GW7 A;  2WIN B;  3ANJ A;  2JKA A;  1IS9 A;  3PZ1 B;  2XN1 A;  4CE7 A;  1NXC A;  2V8K A;  1W2Z A;  1HMW A;  1FP3 A;  2WMK A;  1WU5 A;  1W5Z A;  1G9J A;  1H54 A;  1UT9 A;  2PNC A;  5ILK A;  2WDA A;  1W4N A;  5DGR A;  2ZQ0 A;  5FO9 B;  3T33 A;  1TN6 B;  3W7W A;  1N21 A;  5JPM B;  3BUP A;  1TQW A;  3T2Q A;  1KWF A;  3BUI A;  2DRQ A;  1O1S B;  3SQC A;  3P5P A;  2CWT A;  1CLC A;  3T0B A;  3M00 A;  4KFF A;  1N94 B;  3DSV B;  3E6U A;  5CA3 A;  3K7X A;  1OJM A;  2WMI A;  1GXM A;  2EAC A;  3M7B A;  3ACS A;  1O1R B;  3PYA A;  3WKF A;  1FT2 B;  1R76 A;  5KKB A;  5M7I A;  2RGK A;  3D52 A;  2DRO A;  3MWX A;  1V7W A;  1O7D D;  4GTV B;  3VD5 A;  2X03 A;  3OB8 A;  2H6H B;  3P5R A;  3W7S A;  3E30 B;  3ALA A;  1GXN A;  4FNT A;  1JYV A;  2F7R A;  2F6D A;  1HX9 A;  3QPF A;  4TXT A;  3KBT C;  2WY7 A;  2WVZ A;  1F9G A;  1LTX B;  4Z4J A;  2VN7 A;  1FBO A;  1GXO A;  4D6D A;  1N1Z A;  3VD9 A;  3QDE A;  1CEM A;  1XWQ A;  2XN0 A;  2ZL8 A;  3PQI A;  3LZ9 A;  1GAH A;  1KSD A;  3NJX A;  3PZ2 B;  1V7V A;  4DLO A;  5IK9 A;  2AFA A;  5ILZ A;  5IK6 A;  2Q1F A;  4BOK A;  1H36 A;  1AVK A;  2WVX B;  2WVY A;  3BVV A;  4ZH1 A;  2PN5 A;  1NI1 B;  1D6U A;  3WIQ A;  2EAD A;  3H2W A;  3WC3 A;  1N7Q A;  4KTP A;  2WO0 A;  1JYN A;  2WVX A;  1FPP B;  5E2J A;  1MN0 A;  5JMF A;  2C11 A;  1N7N A;  2V3N A;  2BBC A;  2BB5 A;  5DGQ A;  3M71 A;  3GZK A;  3RSY A;  3G6J B;  3WUX A;  2BRW A;  1TNU B;  3SDR A;  5ILI A;  1G6I A;  2HTB A;  4D6F A;  3E1F 1;  3K11 A;  3A0O A;  1UG9 A;  3MV0 1;  1N1B A;  3VW5 A;  2FYV A;  2D5J A;  3WKG A;  3SFY B;  3DDF A;  3X3Z A;  3QXQ A;  4D1J A;  4D6C A;  3M73 A;  3T08 A;  1C82 A;  3VDB A;  2A73 B;  3QSP A;  5CZL A;  1FCE A;  3HXC B;  4EL8 A;  1HXA A;  1N23 A;  3Q1N A;  4BZF A;  1HN0 A;  1LF6 A;  2FV1 A;  1SPU A;  3Q75 B;  1LF9 A;  3T09 A;  4OZW A;  1RWA A;  3VD3 A;  2CIS A;  2CQT A;  2WW0 A;  1TQT A;  4MBG B;  3WVF A;  3W7X A;  3P2C A;  1O6R A;  1H35 A;  4L9P B;  3CZS A;  4CJ1 A;  4EHM B;  1N20 A;  3QXF A;  2WOH A;  1SNZ A;  1WMO A;  4OZV A;  4OK2 A;  3MI6 A;  2CG0 A;  1AGM A;  1D6Z A;  1L7K A;  1HZF A;  2WCO A;  1QQF A;  4Q88 A;  1RWC A;  3QRY A;  4KKJ A;  2CIR A;  1MMY A;  2QNO A;  4GAX A;  4TTG A;  4D8O A;  2XWJ B;  4D72 A;  1VD5 A;  4KFE A;  2H6I B;  4WVC A;  2P0V A;  3DYM A;  2EAB A;  3VDC A;  5FOB B;  1XW2 A;  3BUB A;  1GLM A;  3HI7 A;  3I3D A;  4M76 A;  3WA2 X;  1WMN A;  1TNB B;  2FUQ A;  1DYU A;  3DPY B;  3OED A;  2GH4 A;  3NFV A;  4MU9 A;  1IQY A;  1HV6 A;  1KZO B;  1GSZ A;  3S9V A;  4BZE A;  3EJR A;  1KS8 A;  1EGU A;  1F9D A;  3MV1 1;  1GAI A;  1N7O A;  2CFG A;  4YDO B;  3TY1 A;  1EKM A;  5JMD A;  1AVL A;  1JOV A;  4FNS A;  3E32 B;  4F13 A;  3VD4 A;  4ONT A;  2ZIR B;  4YDE B;  4FNU A;  1N4Q B;  3BGA A;  1QAF A;  3T0D A;  4JJJ A;  1HMU A;  1HCU A;  3N0F A;  3OBA A;  1SQC A;  2FBA A;  4ZG8 A;  3U7V A;  3QFZ A;  4XUV A;  2WMH A;  2WW3 A;  5EAT A;  1NSR A;  1TQU A;  3SAE A;  1NS0 A;  4L6X A;  1H12 A;  1KRE A;  2XHN A;  3WKH A;  2CFK A;  1JZ2 A;  1F9O A;  1LOH A;  1LXK A;  1O6H A;  2OW7 A;  1K1X A;  2ZXQ A;  1NSM A;  1D8D B;  2B4F A;  1FT1 B;  3QG0 A;  4AYP A;  2BRP A;  1NS7 A;  2HTA A;  2F18 A;  3SDU A;  3MUY 1;  1HXK A;  1JS4 A;  1QWN A;  1KRF A;  3QR8 A;  1KSC A;  3SDT A;  3SFX B;  1MMU A;  1H3A A;  1N24 A;  3E73 A;  5EAS A;  3BVT A;  1TU5 A;  1IA7 A;  4KTR A;  3BUD A;  1SO0 A;  1N7P A;  3I3E A;  3M7E A;  4MMH A;  3AMO B;  1LVN A;  1NS8 A;  2CQS A;  1WZZ A;  3J7H A;  3W7T A;  2ONH A;  2Y74 A;  4TF4 A;  2ALW A;  4FJQ A;  2DRR A;  3EJU A;  2JKE A;  1F4A A;  3AFJ A;  4GTO B;  4D4C A;  3W5M A;  4FNQ A;  2C10 A;  4FNV A;  3PYB A;  4DUV A;  3D50 A;  3F59 A;  2GOX A;  2JG0 A;  4KFD A;  3DSW B;  3HXE B;  3PZ3 B;  4D6G A;  1IVW A;  4D6E A;  2WYH A;  1JYX A;  4Q2B A;  1TN7 B;  1W6J A;  4FNP A;  3S4B A;  2JF4 A;  3E33 B;  3KBU C;  3DX3 A;  1HN1 A;  1LXM A;  3DDG A;  3EU8 A;  3ACT A;  1H3B A;  3Q73 B;  2RI8 A;  3Q78 B;  1NSV A;  4E1Y A;  2OQE A;  1YGA A;  3DSU B;  4D4B A;  1W6G A;  3IAQ A;  3EJP A;  1JZ7 A;  2WMJ A;  1UI7 A;  2XN2 A;  4WVB A;  1K72 A;  1JZ3 A;  1OAC A;  3NNB A;  4Z4L A;  4EV2 A;  2XWB B;  2WY8 A;  1IVX A;  3VDA A;  3KN4 A;  2OKX A;  3GT5 A;  1I8Q A;  1TNY B;  4DUW A;  2F1B A;  5IKA A;  1HM3 A;  1JYW A;  3UD2 A;  4ZRP A;  4DUX A;  2YIK A;  4K3A A;  1N95 B;  1X1H A;  4ZRQ A;  1D6Y A;  3VXD A;  2YFO A;  3X40 A;  1RWH A;  2D8L A;  4D4D A;  1H39 A;  3LVT A;  5ILH A;  3LOY A;  1S64 B;  4FUS A;  3TF4 A;  1FBW A;  1JCR B;  4LNB B;  5A1A A;  2GZ6 A;  3CZJ A;  3NBJ A;  4CJ0 A;  5M7Y A;  3D5R A;  3E34 B;  3S4D A;  4K35 A;  3M01 A;  3M02 A;  1N22 A;  3I3B A;  4LIX A;  4GTQ B; 
#chains in the Genus database with same CATH homology
 3T0B A;  3DYO A;  3DCD A;  3MV1 1;  1W3Y A;  1N7O A;  3MUZ 1;  3TY1 A;  2WW1 A;  3IAP A;  5JMD A;  4RNL A;  1JOV A;  3VSN A;  4F13 A;  1NSX A;  1OJM A;  2WMI A;  3VD4 A;  1F4H A;  1YQ2 A;  3MWX A;  3BGA A;  3T2P A;  3T0D A;  2WMG A;  1HMU A;  3VD5 A;  2X03 A;  3OB8 A;  1JZ8 A;  4BZE A;  1DP0 A;  1MMZ A;  3OBA A;  1QAZ A;  1JYV A;  2E24 A;  2WMH A;  2WVZ A;  2WW3 A;  3WFA A;  1F9G A;  1X1I A;  1F1S A;  1NSR A;  1N7R A;  1NS0 A;  2XHN A;  3DEC A;  2WMF A;  1JZ2 A;  1LOH A;  4D6D A;  1LXK A;  3VD9 A;  2CIQ A;  4AQ0 A;  1K1X A;  2ZXQ A;  1NSM A;  5A1A A;  4D6H A;  4NEI A;  3NJX A;  2HTA A;  1JZ6 A;  2BRP A;  1NS7 A;  1CB8 A;  1X1J A;  1PX4 A;  3MUY 1;  2Q1F A;  2WVX B;  2WVY A;  5E1Q A;  3SEP A;  1JZ4 A;  1MMU A;  1PX3 A;  1N7Q A;  1SO0 A;  1N7P A;  3I3E A;  2BRV X;  4MMH A;  3IMH A;  1NS8 A;  1JYN A;  2WVX A;  3AFL A;  1NKG A;  4D6J A;  1NS4 A;  3E80 A;  1OJN A;  1K1Y A;  1MN0 A;  5JMF A;  3J7H A;  3OS7 A;  1N7N A;  4D6I A;  1MMX A;  3BS6 A;  3NJV A;  3T2O A;  2JKE A;  1F4A A;  3E7J A;  4FNV A;  2BRW A;  3A24 A;  4DUV A;  3VD7 A;  1J0N A;  2HTB A;  4BZG A;  4D6F A;  3E1F 1;  1OJP A;  3A0O A;  1NSU A;  1UG9 A;  4D6G A;  4D6E A;  2WZS A;  3MV0 1;  1JYX A;  4OJZ A;  4J5T A;  3VD3 A;  1JZ5 A;  4D6C A;  1L7J A;  3T08 A;  1C82 A;  3VDB A;  1HN1 A;  1LXM A;  4BZF A;  3Q1N A;  3K25 A;  1NSV A;  4MMI A;  4E1Y A;  1HN0 A;  1LF6 A;  2FUT A;  1Z45 A;  1YGA A;  1LF9 A;  3BLC A;  3ECQ A;  4OZW A;  1K1W A;  3IAQ A;  1RWA A;  1RWF A;  2CIS A;  2WW0 A;  2WW2 A;  3T09 A;  3VSM A;  1NS2 A;  2D73 A;  2WMJ A;  3WVF A;  1JZ7 A;  3NRE A;  1JZ3 A;  1LUR A;  3NNB A;  2WMI B;  3VDA A;  1SNZ A;  4OZV A;  1ULV A;  4OK2 A;  1NSS A;  1I8Q A;  4DUW A;  2E22 A;  2XSG A;  1L7K A;  1NSZ A;  1HM2 A;  1HM3 A;  3T0A A;  2WCO A;  1JYW A;  1RWC A;  2CIR A;  4DUX A;  1OJO A;  1MMY A;  1X1H A;  4OK4 A;  2JKA A;  4TTG A;  2JKP A;  1RWH A;  4D72 A;  1RWG A;  4BZH A;  3DYP A;  1HMW A;  3DYM A;  2WMK A;  4F10 A;  3VDC A;  3I3D A;  3CZJ A;  2FUQ A;  2WDA A;  1J0M A;  3NFV A;  2ZQ0 A;  1HV6 A;  1RW9 A;  4D71 A;  1TXK A;  3I3B A;  3T2Q A;  1EGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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