2BRVX

Crystal structure of streptococcus pneumoniae hyaluronate lyase from 70percent saturated malonate.
Total Genus 192
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
192
sequence length
722
structure length
714
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSILWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Alternate Structural Conformations of Streptococcus Pneumoniae Hyaluronan Lyase: Insights Into Enzyme Flexibility and Underlying Molecular Mechanism of Action.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
molecule keywords HYALURONATE LYASE
total genus 192
structure length 714
sequence length 722
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2005-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
X PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
X PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2brvX01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2brvX03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2brvX02
1LF9A 4DUXA 4E1YA 1W3YA 4MMHA 4OZVA 4D6DA 5E1QA 1JZ5A 1NSXA 1RWHA 1MMYA 1OJNA 2WW0A 1UG9A 1MMZA 3J7HA 1C82A 2XHNA 4MMIA 2E22A 3IAQA 3VD3A 4D6CA 4D6EA 2WVYA 1YQ2A 3SEPA 2D73A 1NKGA 3T0AA 5A1AA 3VD5A 1RWCA 2WMJA 4OJZA 4D6HA 4AQ0A 1ULVA 1RWFA 4NEIA 1F4AA 2BRWA 2Q1FA 3E7JA 2JKEA 3T2OA 1NS4A 4D6IA 1JZ3A 1OJPA 3VDCA 3NNBA 4OZWA 2WVZA 3T0DA 2WZSA 3E80A 3MV11 3E1F1 1JZ6A 1NSSA 1PX3A 1YGAA 2E24A 3Q1NA 1NS8A 1X1HA 2HTBA 4DUWA 1HM3A 1N7PA 2WMIA 1NSMA 1SNZA 1LURA 1NSRA 3DYMA 1F9GA 2JKAA 4F10A 2JKPA 3MUY1 3IMHA 1X1IA 4BZGA 2CIRA 5JMDA 1HMUA 3VSMA 2WMIB 1N7RA 1LXMA 1K1XA 3VDBA 1K1YA 2WMKA 3VD7A 2WVXA 3VSNA 3AFLA 1X1JA 1MMUA 2FUQA 3T2QA 1Z45A 1HMWA 3NJXA 1K1WA 4OK2A 2ZQ0A 4D72A 3VD4A 1JYNA 4OK4A 3T0BA 1N7NA 1JZ2A 1JZ8A 3K25A 3I3EA 1L7JA 2CISA 4BZEA 1HN1A 4D6JA 4D71A 1F1SA 1HV6A 1J0NA 1HN0A 1RW9A 3A24A 3OB8A 2WVXB 1JYWA 1TXKA 2BRPA 1MN0A 1JZ4A 1QAZA 2WDAA 4D6FA 2WW3A 3CZJA 3OBAA 3WFAA 4BZFA 1N7OA 1SO0A 3I3BA 3NJVA 1OJMA 1JZ7A 1NSZA 1NSUA 1NSVA 1J0MA 1HM2A 3VDAA 1F4HA 2WCOA 3DECA 4FNVA 1PX4A 1RWGA 3IAPA 1NS7A 3NREA 3VD9A 1OJOA 1MMXA 4F13A 3BGAA 2BRVX 3DCDA 3MWXA 2WW1A 2WW2A 2XSGA 1I8QA 3I3DA 1EGUA 3T09A 4DUVA 1NS2A 5JMFA 4TTGA 1JOVA 4BZHA 2X03A 1L7KA 1N7QA 3MV01 3DYOA 3DYPA 2WMFA 4RNLA 3T2PA 1CB8A 2HTAA 2WMGA 4D6GA 3OS7A 1JYXA 1LOHA 2WMHA 1LF6A 1NS0A 1RWAA 3NFVA 2FUTA 3T08A 2ZXQA 1JYVA 3ECQA 3MUZ1 3A0OA 1LXKA 2CIQA 1DP0A
chains in the Genus database with same CATH superfamily
2J5CA 1LD7B 1KZOB 3SDVA 4OZVA 1TN7B 3M72A 1OACA 2D8LA 3E37B 1RWHA 4YDOB 3QT3A 1UI8A 1UG9A 2WO0A 2WYHA 2XHNA 3VD3A 3D4ZA 2WVYA 2D73A 1NKGA 3PYAA 3VD5A 3UD1A 1D6ZA 2CWTA 1RWCA 2WMJA 1IA7A 1HX9A 3BUBA 4D6HA 2F6DA 4AQ0A 1W2ZA 1RWFA 1F4AA 4KFFA 2EAEA 4YCRA 4V1RA 2W0QA 3BLBA 4WVBA 2JKEA 3EJPA 3T2OA 4D6IA 3H2WA 1SIHA 3BUIA 1GXOA 1XWTA 3SXXA 1HTYA 5AGDA 4OZWA 1IQXA 2WVZA 3M00A 2WZSA 2PNCA 2YX9A 1H3CA 2BB6A 3DSUB 1YGAA 3SX1A 5GZKA 4Z4JA 1W6KA 1TN6B 2FV1A 5JPMB 2V8IA 2ALWA 1TNUB 4DUWA 5FO8B 1N7PA 3K11A 2PN5A 1LURA 2NVPA 1NSRA 4CJ1A 1UI7A 4F10A 2IEJB 4GTVB 3KQ4A 2JKAA 3MUY1 1FBOA 2YIKA 3D50A 3PZ3B 3HIGA 4DI5A 1TNOB 5ILDA 1IVWA 1QWUA 1HMUA 3VSMA 1WMOA 3Q78B 1N7RA 2WMIB 4FNRA 1K72A 3VDBA 3RX5A 4FNTA 2WMKA 1HXKA 2FUQA 3EJUA 3KLSA 3T2QA 3LVTA 4GTQB 1CEMA 1O6HA 3W7TA 4BTWA 3E33B 1KS8A 3W5MA 3T0BA 1N7NA 1QQFA 3K25A 1L7JA 1GXMA 2CISA 3Q79B 3G6JB 4D6JA 4GTOB 1F1SA 1HN0A 4DOEA 4D71A 1IVVA 3G4DA 3D5SA 2BRPA 2SQCA 2XFGA 1QAZA 1HWWA 2DROA 2ZZRA 2I07B 3S4BA 2RDYA 3F59A 3EU5B 4ZH1A 1H39A 3RRSA 1NSZA 3BVXA 1J0MA 3IAPA 3DECA 2DRSA 2QNOA 1QWNA 3RX7A 1MMXA 1TQSA 2E2TA 5GY3A 3MWXA 3MPHA 1KKTA 2XSGA 1N4QB 3DDGA 1EGUA 3DX0A 5IKAA 4D4BA 2F0YB 4DUVA 2DRQA 2KXRA 3SQCA 3GLYA 4BZHA 2X03A 2CWUA 1N7QA 3WVFA 2ONGA 4ZH5A 1CB8A 1N21A 2JJBA 2H6FB 3OS7A 3DDFA 3ANIA 5IL8A 1LF6A 2CG1A 3S9VA 3NFVA 1NI1B 3ON6A 4QT9A 3X3YA 2CWVA 3WKFA 5EATA 3CZNA 3ECQA 3MUZ1 1W6CA 2F7RA 4D4CA 4D6DA 1FMIA 2G02A 3WKHA 1TQWA 1MMYA 1OJNA 1L2AA 2CG0A 1TQUA 3M01A 2CFWA 1LVNA 4L0GA 4MMIA 3SAEA 2AHFA 5FO7B 3W7SA 1N1BA 2VN7A 1A2VA 3QFYA 1PS3A 1H36A 4KFEA 3C72B 3M7LA 2FV0A 5KKBA 3AFJA 1KFGA 2NOJA 1DL2A 2Q1FA 3Q7AB 3HXEB 3KSQB 2F7QA 3W7UA 1JZ3A 4D94A 3N0FA 3M71A 4DLQA 3K5TA 1OJPA 3KBUC 4YDEB 2R2LB 4GTSB 4WVCA 3E1F1 2ZBLA 1PX3A 3H7LA 2WOHA 1UT9A 3S4AA 2E24A 4D1IA 2WIIB 2F1AA 2CFKA 2WMIA 1NSMA 3Q73B 2D5JA 1SNZA 3DYMA 5CA3A 4FXGB 1QAFA 3KN4A 1SIIA 2XN0A 1X1IA 3X40A 1N22A 1N95B 4GTMB 3SFYB 1QALA 4JJJA 5JMDA 1R34A 2WOFA 3PGBA 1GHQA 1DYUA 3WIQA 4CE7A 2CFGA 1NC5A 2EACA 2EABA 3SFXB 5ILHA 3N9HA 3VD7A 3QRYA 2WVXA 3AFLA 1H3BA 1MMUA 1H37A 1JCQB 5IK6A 3X41A 1O79A 1LTXB 1X9DA 3BUDA 2Y74A 3NBJA 1JCSB 4OK4A 3E32B 3W5NA 1JZ2A 4KTRA 4D8OA 1HN1A 1H35A 2CQTA 1H14A 4XUVA 2Z07A 3U7VA 3A24A 1J0NA 3KBTC 1FPPB 1O5MB 1N4RB 1GSZA 1TF4A 1IVXA 2WDAA 4MU9A 3EZ8A 2WW3A 1GA2A 1JRQA 1R33A 3OBAA 3H3KA 1N7OA 5IK0A 1FBWA 1OJMA 3QWTA 5DHKA 4KTPA 3UD2A 1NSVA 3DPYB 3VDAA 1JCRB 5GW7A 1N94B 3AMOA 4FNVA 1PX4A 3NREA 5M7YA 1NS7A 3E34B 1N4PB 4BTYA 3K7XA 2WYIA 3DCDA 4Q2BA 1FO2A 2FYVA 1GAIA 1I8QA 3M76A 1LD8B 3OEDA 1NS2A 1H13A 4EL8A 1JOVA 4L9PB 1N4SB 2WY7A 3EU8A 3P5RA 4FUSA 1HZFA 5CD2A 1O1TB 3MV01 3CZSA 3DYPA 3PZ4B 3PZ1B 1FO3A 1MZCB 3HXBB 2KXSA 4D6GA 2HTAA 1JYXA 4WU0A 1KWFA 3DSSB 2FUTA 3T08A 2ZXQA 1G9GA 2C10A 3A0OA 1LXKA 5ILIA 1X81B 2CIQA 1LF9A 1V5DA 1W3YA 4E1YA 1N24A 5DHIA 2DRRA 3QSPA 4FXKB 3RENA 1NSXA 2OW6A 1JZ5A 3TF4A 2OW7A 1L1YA 4L6XA 1V7VA 2WW0A 3G4FA 3J7HA 1C82A 4GTTB 2WYNA 3RX8A 2E2VA 3X42A 3HI7A 3CU7A 2OKXA 5ILYA 2V3PA 2AFAA 3D4YA 4D6CA 4D6EA 3EJTA 1YQ2A 4FNQA 3SEPA 2OOVA 1UMPA 3WKGA 5ILKA 4OJZA 1AGMA 4LNGB 1AV4A 2A8ZA 1V7XA 1DOGA 1ULVA 4K3AA 1KSDA 4NEIA 2P0VA 1EKMA 4V1SA 3QPFA 2V8JA 2E2UA 3M78A 2YFOA 2EADA 4FJQA 2CFLA 2ZISB 1IS9A 2WY8A 1AYXA 4GTPB 3NNBA 3WUXA 3T0DA 3M7CA 3E80A 5EASA 4D4DA 3QR8A 1WU4A 2BB5A 3DX2A 1SPUA 4BOJA 1RKYA 3M02A 1W6GA 3Q1NA 1NL4B 1HXGA 1WU6A 5C05A 4KFDA 3RSYA 1F9GA 4EV5A 2JKPA 2XQWA 2RI8A 1TQVA 1FAEA 1O6RA 1TN8B 4BZGA 1KSCA 1WMNA 3ALAA 4KKJA 1V7WA 1F9DA 4TXTA 3M77A 3DSXB 3T33A 4AYPA 3W7WA 3W7XA 4GTRB 4ZRQA 3EJSA 3M75A 1QAKA 1SA4B 1HMWA 5CZLA 4DODA 1Z45A 1K1WA 2F7OA 2ZQ0A 1XWQA 4D72A 1WZZA 3VD4A 4FNUA 3BVWA 1JYNA 1FCEA 3OXUA 1JZ8A 1WU5A 2OQEC 3X3ZA 1KRFA 4BZEA 1GXNA 3RJ3A 5DGQA 2FBAA 3N0GA 1WMPA 2BT3A 2B4FA 1HV6A 1JYWA 3X17A 1O1RB 1TXKA 1R76A 5KBPA 1MN0A 3HXCB 1VD5A 2GZ6A 4D6FA 3CV5A 2BBCA 3VW5A 1KZPB 1O1SB 1QBQB 2H6HB 3BVUA 3MI6A 4BZFA 5M7IA 1JZ7A 4BOKA 2XN1A 4EV2A 4ONTA 3QDEA 3HXDB 4EHMB 5IK9A 1US1A 3VD9A 1RWGA 1OJOA 5IM1A 3BGAA 4GAXA 2D1WA 4D1JA 2CFDA 5JMFA 3WC3A 1QSJA 1GAHA 1KREA 5MEHA 3M7EA 4C1SA 3DYOA 3T2PA 2B39A 3ANJA 3GT5A 3Q75B 2WMGA 1LOHA 3S4DA 3EUVB 2F18A 2WMHA 1S63B 3E73A 3Q7FB 2AHGA 3KSLB 1TNZB 3QXFA 4DLOA 3S4CA 1TNBB 4ZG8A 3WA3A 4CJ0A 5IL3A 1D8EB 3VXDA 2CQSA 1JYVA 1RJOA 3SDQA 1G6IA 1DP0A 4KKIA 4LNVA 4DUXA 3D3IA 4MMHA 3P2CA 5E1QA 1IA6A 1NXCA 1IQYA 3WA2X 5FOBB 2Y73A 3PMMA 4RNQA 2H6GB 2JG0A 2V3NA 3HXFB 1IU7A 1FT2B 2XWBB 1MMZA 3BVVA 2E22A 1AVLA 3IAQA 3EJRA 1N9AB 1D6UA 3T0AA 5A1AA 1D8DB 4WVAA 2BEDB 2VN4A 3AMOB 2OQEA 1H12A 1W6JA 3DSTB 1W7CA 4BTXA 2XN2A 2BRWA 2ZIRB 3X3XA 3D52A 3E7JA 2C11A 3WKIA 3GZKA 1NS4A 4Z4LA 4TF4A 3T0UA 3M73A 3D51A 3QT9A 3A3VA 1TNYB 5JPNB 1XW2A 1HXAA 3E30B 1N9EA 1TQTA 3VDCA 1TU5A 2WINB 3MV11 3M7BA 4UFCA 1JZ6A 1NSSA 1G87A 1D6YA 3M74A 3TY1A 2V8KA 2GH4A 4LIXA 1X1HA 1NS8A 3WIRA 2HTBA 2PMVA 1HM3A 3LOYA 3DSVB 3DX3A 3DSWB 1AVKA 4ZRPA 3LZ9A 4Q88A 2H6IB 4D4AA 3BUQA 3IMHA 2CIRA 1SQCA 1QX1A 2RI9A 1LXMA 1K1XA 3DX1A 1K1YA 1W5ZA 3VSNA 1GLMA 1X1JA 2YFNA 1C3DA 2ONHA 3CIHA 3NJXA 2JF4A 4OK2A 2ZL8A 3PYBA 3SDRA 3DRAB 1DCEB 2XWJB 4FNPA 1KSIA 1O7DD 3I3EA 1H54A 3QFZA 5ILZA 1FT1B 3E6UA 5DGRA 1F9OA 5E2JA 1RW9A 3QXQA 3D5RA 2A73B 2WVXB 3OB8A 5ILJA 3ACTA 4AYOA 3SDTA 1JZ4A 1HCUA 3HIIA 4FNSA 2OOVC 3ANKA 4GL3A 3CZJA 2G0DA 3WFAA 1O6QA 5FO9B 1SO0A 1N20A 3BLCA 3I3BA 3NJVA 4LNBB 1G9JA 1H3AA 1FP3A 1V5CA 1PU4A 1NSUA 3BS6A 1HM2A 5EAUA 1F4HA 4M76A 2WCOA 3QG0A 3SDUA 3PZ2B 3P5PA 1N1ZA 3EJQA 4F13A 3PQIA 2BRVX 1IVUA 2GOXA 1W4NA 2WW1A 1N23A 1JS4A 2WGQA 2WW2A 3BVTA 3I3DA 3T09A 4K35A 4TTGA 1HXCA 1RQ5A 3DX4A 2FUZA 4J5TA 1L7KA 2F7PA 3WIWA 2RGKA 2WMFA 4MBGB 4RNLA 3EQAA 3KIIA 1SA5B 3BUPA 4AYQA 1S64B 1NS0A 1RWAA 3NBBA 5IKHA 3ACSA 2F1BA 4AYRA 1CLCA
chains in the Genus database with same CATH topology
1LF9A 4DUXA 4E1YA 1W3YA 4MMHA 4OZVA 4D6DA 5E1QA 1JZ5A 1NSXA 1RWHA 1MMYA 1OJNA 2WW0A 1UG9A 1MMZA 3J7HA 1C82A 2XHNA 4MMIA 2E22A 3IAQA 3VD3A 4D6CA 4D6EA 2WVYA 1YQ2A 3SEPA 2D73A 1NKGA 3T0AA 5A1AA 3VD5A 1RWCA 2WMJA 4OJZA 4D6HA 4AQ0A 1ULVA 1RWFA 4NEIA 1F4AA 2BRWA 2Q1FA 3E7JA 2JKEA 3T2OA 1NS4A 4D6IA 1JZ3A 1OJPA 3VDCA 3NNBA 4OZWA 2WVZA 3T0DA 2WZSA 3E80A 3MV11 3E1F1 1JZ6A 1NSSA 1PX3A 1YGAA 3TY1A 2E24A 3Q1NA 1NS8A 1X1HA 2HTBA 4DUWA 1HM3A 1N7PA 2WMIA 1NSMA 1SNZA 1LURA 1NSRA 3DYMA 1F9GA 2JKAA 4F10A 2JKPA 3MUY1 3IMHA 1X1IA 4BZGA 2CIRA 5JMDA 1HMUA 3VSMA 2WMIB 1N7RA 1LXMA 1K1XA 3VDBA 1K1YA 2WMKA 3VD7A 2WVXA 3VSNA 3AFLA 1X1JA 1MMUA 2FUQA 3T2QA 1Z45A 1HMWA 3NJXA 1K1WA 4OK2A 2ZQ0A 4D72A 3VD4A 1JYNA 4OK4A 3T0BA 1N7NA 1JZ2A 1JZ8A 3K25A 3I3EA 1L7JA 2CISA 4BZEA 1HN1A 4D6JA 4D71A 1F1SA 1HV6A 1J0NA 1HN0A 1RW9A 3A24A 3OB8A 2WVXB 1JYWA 1TXKA 2BRPA 1MN0A 1JZ4A 1QAZA 2WDAA 4D6FA 2WW3A 3CZJA 3OBAA 3WFAA 4BZFA 1N7OA 1SO0A 3BLCA 3I3BA 3NJVA 1OJMA 1JZ7A 1NSZA 1NSUA 3BS6A 1NSVA 1J0MA 1HM2A 3VDAA 1F4HA 2WCOA 3DECA 4FNVA 1PX4A 1RWGA 3IAPA 1NS7A 3NREA 3VD9A 1OJOA 1MMXA 4F13A 3BGAA 2BRVX 3DCDA 3MWXA 2WW1A 2WW2A 2XSGA 1I8QA 3I3DA 1EGUA 3T09A 4DUVA 1NS2A 5JMFA 4TTGA 1JOVA 4BZHA 2X03A 1L7KA 4J5TA 1N7QA 3MV01 3DYOA 3WVFA 3DYPA 2WMFA 4RNLA 3T2PA 1CB8A 2HTAA 2WMGA 4D6GA 3OS7A 1JYXA 1LOHA 2WMHA 1LF6A 1NS0A 1RWAA 3NFVA 2FUTA 3T08A 2ZXQA 1JYVA 3ECQA 3MUZ1 3A0OA 1LXKA 2CIQA 1DP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LF9 A;  4DUX A;  4E1Y A;  1W3Y A;  4MMH A;  4OZV A;  4D6D A;  5E1Q A;  1JZ5 A;  1NSX A;  1RWH A;  1MMY A;  1OJN A;  2WW0 A;  1UG9 A;  1MMZ A;  3J7H A;  1C82 A;  2XHN A;  4MMI A;  2E22 A;  3IAQ A;  3VD3 A;  4D6C A;  4D6E A;  2WVY A;  1YQ2 A;  3SEP A;  2D73 A;  1NKG A;  3T0A A;  5A1A A;  3VD5 A;  1RWC A;  2WMJ A;  4OJZ A;  4D6H A;  4AQ0 A;  1ULV A;  1RWF A;  4NEI A;  1F4A A;  2BRW A;  2Q1F A;  3E7J A;  2JKE A;  3T2O A;  1NS4 A;  4D6I A;  1JZ3 A;  1OJP A;  3VDC A;  3NNB A;  4OZW A;  2WVZ A;  3T0D A;  2WZS A;  3E80 A;  3MV1 1;  3E1F 1;  1JZ6 A;  1NSS A;  1PX3 A;  1YGA A;  2E24 A;  3Q1N A;  1NS8 A;  1X1H A;  2HTB A;  4DUW A;  1HM3 A;  1N7P A;  2WMI A;  1NSM A;  1SNZ A;  1LUR A;  1NSR A;  3DYM A;  1F9G A;  2JKA A;  4F10 A;  2JKP A;  3MUY 1;  3IMH A;  1X1I A;  4BZG A;  2CIR A;  5JMD A;  1HMU A;  3VSM A;  2WMI B;  1N7R A;  1LXM A;  1K1X A;  3VDB A;  1K1Y A;  2WMK A;  3VD7 A;  2WVX A;  3VSN A;  3AFL A;  1X1J A;  1MMU A;  2FUQ A;  3T2Q A;  1Z45 A;  1HMW A;  3NJX A;  1K1W A;  4OK2 A;  2ZQ0 A;  4D72 A;  3VD4 A;  1JYN A;  4OK4 A;  3T0B A;  1N7N A;  1JZ2 A;  1JZ8 A;  3K25 A;  3I3E A;  1L7J A;  2CIS A;  4BZE A;  1HN1 A;  4D6J A;  4D71 A;  1F1S A;  1HV6 A;  1J0N A;  1HN0 A;  1RW9 A;  3A24 A;  3OB8 A;  2WVX B;  1JYW A;  1TXK A;  2BRP A;  1MN0 A;  1JZ4 A;  1QAZ A;  2WDA A;  4D6F A;  2WW3 A;  3CZJ A;  3OBA A;  3WFA A;  4BZF A;  1N7O A;  1SO0 A;  3I3B A;  3NJV A;  1OJM A;  1JZ7 A;  1NSZ A;  1NSU A;  1NSV A;  1J0M A;  1HM2 A;  3VDA A;  1F4H A;  2WCO A;  3DEC A;  4FNV A;  1PX4 A;  1RWG A;  3IAP A;  1NS7 A;  3NRE A;  3VD9 A;  1OJO A;  1MMX A;  4F13 A;  3BGA A;  2BRV X;  3DCD A;  3MWX A;  2WW1 A;  2WW2 A;  2XSG A;  1I8Q A;  3I3D A;  1EGU A;  3T09 A;  4DUV A;  1NS2 A;  5JMF A;  4TTG A;  1JOV A;  4BZH A;  2X03 A;  1L7K A;  1N7Q A;  3MV0 1;  3DYO A;  3DYP A;  2WMF A;  4RNL A;  3T2P A;  1CB8 A;  2HTA A;  2WMG A;  4D6G A;  3OS7 A;  1JYX A;  1LOH A;  2WMH A;  1LF6 A;  1NS0 A;  1RWA A;  3NFV A;  2FUT A;  3T08 A;  2ZXQ A;  1JYV A;  3ECQ A;  3MUZ 1;  3A0O A;  1LXK A;  2CIQ A;  1DP0 A; 
#chains in the Genus database with same CATH topology
 2J5C A;  1LD7 B;  1KZO B;  3SDV A;  4OZV A;  1TN7 B;  3M72 A;  1OAC A;  2D8L A;  3E37 B;  1RWH A;  4YDO B;  3QT3 A;  1UI8 A;  1UG9 A;  2WO0 A;  2WYH A;  2XHN A;  3VD3 A;  3D4Z A;  2WVY A;  2D73 A;  1NKG A;  3PYA A;  3VD5 A;  3UD1 A;  1D6Z A;  2CWT A;  1RWC A;  2WMJ A;  1IA7 A;  1HX9 A;  3BUB A;  4D6H A;  2F6D A;  4AQ0 A;  1W2Z A;  1RWF A;  1F4A A;  4KFF A;  2EAE A;  4YCR A;  4V1R A;  2W0Q A;  3BLB A;  4WVB A;  2JKE A;  3EJP A;  3T2O A;  4D6I A;  3H2W A;  1SIH A;  3BUI A;  1GXO A;  1XWT A;  3SXX A;  1HTY A;  5AGD A;  4OZW A;  1IQX A;  2WVZ A;  3M00 A;  2WZS A;  2PNC A;  2YX9 A;  1H3C A;  2BB6 A;  3DSU B;  1YGA A;  3SX1 A;  5GZK A;  4Z4J A;  1W6K A;  1TN6 B;  2FV1 A;  5JPM B;  2V8I A;  2ALW A;  1TNU B;  4DUW A;  5FO8 B;  1N7P A;  3K11 A;  2PN5 A;  1LUR A;  2NVP A;  1NSR A;  4CJ1 A;  1UI7 A;  4F10 A;  2IEJ B;  4GTV B;  3KQ4 A;  2JKA A;  3MUY 1;  1FBO A;  2YIK A;  3D50 A;  3PZ3 B;  3HIG A;  4DI5 A;  1TNO B;  5ILD A;  1IVW A;  1QWU A;  1HMU A;  3VSM A;  1WMO A;  3Q78 B;  1N7R A;  2WMI B;  4FNR A;  1K72 A;  3VDB A;  3RX5 A;  4FNT A;  2WMK A;  1HXK A;  2FUQ A;  3EJU A;  3KLS A;  3T2Q A;  3LVT A;  4GTQ B;  1CEM A;  1O6H A;  3W7T A;  4BTW A;  3E33 B;  1KS8 A;  3W5M A;  3T0B A;  1N7N A;  1QQF A;  3K25 A;  1L7J A;  1GXM A;  2CIS A;  3Q79 B;  3G6J B;  4D6J A;  4GTO B;  1F1S A;  1HN0 A;  4DOE A;  4D71 A;  1IVV A;  3G4D A;  3D5S A;  2BRP A;  2SQC A;  2XFG A;  1QAZ A;  1HWW A;  2DRO A;  2ZZR A;  2I07 B;  3S4B A;  2RDY A;  3F59 A;  3EU5 B;  4ZH1 A;  1H39 A;  3RRS A;  1NSZ A;  3BVX A;  1J0M A;  3IAP A;  3DEC A;  2DRS A;  2QNO A;  1QWN A;  3RX7 A;  1MMX A;  1TQS A;  2E2T A;  5GY3 A;  3MWX A;  3MPH A;  1KKT A;  2XSG A;  1N4Q B;  3DDG A;  1EGU A;  3DX0 A;  5IKA A;  4D4B A;  2F0Y B;  4DUV A;  2DRQ A;  2KXR A;  3SQC A;  3GLY A;  4BZH A;  2X03 A;  2CWU A;  1N7Q A;  3WVF A;  2ONG A;  4ZH5 A;  1CB8 A;  1N21 A;  2JJB A;  2H6F B;  3OS7 A;  3DDF A;  3ANI A;  5IL8 A;  1LF6 A;  2CG1 A;  3S9V A;  3NFV A;  1NI1 B;  3ON6 A;  4QT9 A;  3X3Y A;  2CWV A;  3WKF A;  5EAT A;  3CZN A;  3ECQ A;  3MUZ 1;  1W6C A;  2F7R A;  4D4C A;  4D6D A;  1FMI A;  2G02 A;  3WKH A;  1TQW A;  1MMY A;  1OJN A;  1L2A A;  2CG0 A;  1TQU A;  3M01 A;  2CFW A;  1LVN A;  4L0G A;  4MMI A;  3SAE A;  2AHF A;  5FO7 B;  3W7S A;  1N1B A;  2VN7 A;  1A2V A;  3QFY A;  1PS3 A;  1H36 A;  4KFE A;  3C72 B;  3M7L A;  2FV0 A;  5KKB A;  3AFJ A;  1KFG A;  2NOJ A;  1DL2 A;  2Q1F A;  3Q7A B;  3HXE B;  3KSQ B;  2F7Q A;  3W7U A;  1JZ3 A;  4D94 A;  3N0F A;  3M71 A;  4DLQ A;  3K5T A;  1OJP A;  3KBU C;  4YDE B;  2R2L B;  4GTS B;  4WVC A;  3E1F 1;  2ZBL A;  1PX3 A;  3H7L A;  2WOH A;  1UT9 A;  3S4A A;  2E24 A;  4D1I A;  2WII B;  2F1A A;  2CFK A;  2WMI A;  1NSM A;  3Q73 B;  2D5J A;  1SNZ A;  3DYM A;  5CA3 A;  4FXG B;  1QAF A;  3KN4 A;  1SII A;  2XN0 A;  1X1I A;  3X40 A;  1N22 A;  1N95 B;  4GTM B;  3SFY B;  1QAL A;  4JJJ A;  5JMD A;  1R34 A;  2WOF A;  3PGB A;  1GHQ A;  1DYU A;  3WIQ A;  4CE7 A;  2CFG A;  1NC5 A;  2EAC A;  2EAB A;  3SFX B;  5ILH A;  3N9H A;  3VD7 A;  3QRY A;  2WVX A;  3AFL A;  1H3B A;  1MMU A;  1H37 A;  1JCQ B;  5IK6 A;  3X41 A;  1O79 A;  1LTX B;  1X9D A;  3BUD A;  2Y74 A;  3NBJ A;  1JCS B;  4OK4 A;  3E32 B;  3W5N A;  1JZ2 A;  4KTR A;  4D8O A;  1HN1 A;  1H35 A;  2CQT A;  1H14 A;  4XUV A;  2Z07 A;  3U7V A;  3A24 A;  1J0N A;  3KBT C;  1FPP B;  1O5M B;  1N4R B;  1GSZ A;  1TF4 A;  1IVX A;  2WDA A;  4MU9 A;  3EZ8 A;  2WW3 A;  1GA2 A;  1JRQ A;  1R33 A;  3OBA A;  3H3K A;  1N7O A;  5IK0 A;  1FBW A;  1OJM A;  3QWT A;  5DHK A;  4KTP A;  3UD2 A;  1NSV A;  3DPY B;  3VDA A;  1JCR B;  5GW7 A;  1N94 B;  3AMO A;  4FNV A;  1PX4 A;  3NRE A;  5M7Y A;  1NS7 A;  3E34 B;  1N4P B;  4BTY A;  3K7X A;  2WYI A;  3DCD A;  4Q2B A;  1FO2 A;  2FYV A;  1GAI A;  1I8Q A;  3M76 A;  1LD8 B;  3OED A;  1NS2 A;  1H13 A;  4EL8 A;  1JOV A;  4L9P B;  1N4S B;  2WY7 A;  3EU8 A;  3P5R A;  4FUS A;  1HZF A;  5CD2 A;  1O1T B;  3MV0 1;  3CZS A;  3DYP A;  3PZ4 B;  3PZ1 B;  1FO3 A;  1MZC B;  3HXB B;  2KXS A;  4D6G A;  2HTA A;  1JYX A;  4WU0 A;  1KWF A;  3DSS B;  2FUT A;  3T08 A;  2ZXQ A;  1G9G A;  2C10 A;  3A0O A;  1LXK A;  5ILI A;  1X81 B;  2CIQ A;  1LF9 A;  1V5D A;  1W3Y A;  4E1Y A;  1N24 A;  5DHI A;  2DRR A;  3QSP A;  4FXK B;  3REN A;  1NSX A;  2OW6 A;  1JZ5 A;  3TF4 A;  2OW7 A;  1L1Y A;  4L6X A;  1V7V A;  2WW0 A;  3G4F A;  3J7H A;  1C82 A;  4GTT B;  2WYN A;  3RX8 A;  2E2V A;  3X42 A;  3HI7 A;  3CU7 A;  2OKX A;  5ILY A;  2V3P A;  2AFA A;  3D4Y A;  4D6C A;  4D6E A;  3EJT A;  1YQ2 A;  4FNQ A;  3SEP A;  2OOV A;  1UMP A;  3WKG A;  5ILK A;  4OJZ A;  1AGM A;  4LNG B;  1AV4 A;  2A8Z A;  1V7X A;  1DOG A;  1ULV A;  4K3A A;  1KSD A;  4NEI A;  2P0V A;  1EKM A;  4V1S A;  3QPF A;  2V8J A;  2E2U A;  3M78 A;  2YFO A;  2EAD A;  4FJQ A;  2CFL A;  2ZIS B;  1IS9 A;  2WY8 A;  1AYX A;  4GTP B;  3NNB A;  3WUX A;  3T0D A;  3M7C A;  3E80 A;  5EAS A;  4D4D A;  3QR8 A;  1WU4 A;  2BB5 A;  3DX2 A;  1SPU A;  4BOJ A;  1RKY A;  3M02 A;  1W6G A;  3Q1N A;  1NL4 B;  1HXG A;  1WU6 A;  5C05 A;  4KFD A;  3RSY A;  1F9G A;  4EV5 A;  2JKP A;  2XQW A;  2RI8 A;  1TQV A;  1FAE A;  1O6R A;  1TN8 B;  4BZG A;  1KSC A;  1WMN A;  3ALA A;  4KKJ A;  1V7W A;  1F9D A;  4TXT A;  3M77 A;  3DSX B;  3T33 A;  4AYP A;  3W7W A;  3W7X A;  4GTR B;  4ZRQ A;  3EJS A;  3M75 A;  1QAK A;  1SA4 B;  1HMW A;  5CZL A;  4DOD A;  1Z45 A;  1K1W A;  2F7O A;  2ZQ0 A;  1XWQ A;  4D72 A;  1WZZ A;  3VD4 A;  4FNU A;  3BVW A;  1JYN A;  1FCE A;  3OXU A;  1JZ8 A;  1WU5 A;  2OQE C;  3X3Z A;  1KRF A;  4BZE A;  1GXN A;  3RJ3 A;  5DGQ A;  2FBA A;  3N0G A;  1WMP A;  2BT3 A;  2B4F A;  1HV6 A;  1JYW A;  3X17 A;  1O1R B;  1TXK A;  1R76 A;  5KBP A;  1MN0 A;  3HXC B;  1VD5 A;  2GZ6 A;  4D6F A;  3CV5 A;  2BBC A;  3VW5 A;  1KZP B;  1O1S B;  1QBQ B;  2H6H B;  3BVU A;  3MI6 A;  4BZF A;  5M7I A;  1JZ7 A;  4BOK A;  2XN1 A;  4EV2 A;  4ONT A;  3QDE A;  3HXD B;  4EHM B;  5IK9 A;  1US1 A;  3VD9 A;  1RWG A;  1OJO A;  5IM1 A;  3BGA A;  4GAX A;  2D1W A;  4D1J A;  2CFD A;  5JMF A;  3WC3 A;  1QSJ A;  1GAH A;  1KRE A;  5MEH A;  3M7E A;  4C1S A;  3DYO A;  3T2P A;  2B39 A;  3ANJ A;  3GT5 A;  3Q75 B;  2WMG A;  1LOH A;  3S4D A;  3EUV B;  2F18 A;  2WMH A;  1S63 B;  3E73 A;  3Q7F B;  2AHG A;  3KSL B;  1TNZ B;  3QXF A;  4DLO A;  3S4C A;  1TNB B;  4ZG8 A;  3WA3 A;  4CJ0 A;  5IL3 A;  1D8E B;  3VXD A;  2CQS A;  1JYV A;  1RJO A;  3SDQ A;  1G6I A;  1DP0 A;  4KKI A;  4LNV A;  4DUX A;  3D3I A;  4MMH A;  3P2C A;  5E1Q A;  1IA6 A;  1NXC A;  1IQY A;  3WA2 X;  5FOB B;  2Y73 A;  3PMM A;  4RNQ A;  2H6G B;  2JG0 A;  2V3N A;  3HXF B;  1IU7 A;  1FT2 B;  2XWB B;  1MMZ A;  3BVV A;  2E22 A;  1AVL A;  3IAQ A;  3EJR A;  1N9A B;  1D6U A;  3T0A A;  5A1A A;  1D8D B;  4WVA A;  2BED B;  2VN4 A;  3AMO B;  2OQE A;  1H12 A;  1W6J A;  3DST B;  1W7C A;  4BTX A;  2XN2 A;  2BRW A;  2ZIR B;  3X3X A;  3D52 A;  3E7J A;  2C11 A;  3WKI A;  3GZK A;  1NS4 A;  4Z4L A;  4TF4 A;  3T0U A;  3M73 A;  3D51 A;  3QT9 A;  3A3V A;  1TNY B;  5JPN B;  1XW2 A;  1HXA A;  3E30 B;  1N9E A;  1TQT A;  3VDC A;  1TU5 A;  2WIN B;  3MV1 1;  3M7B A;  4UFC A;  1JZ6 A;  1NSS A;  1G87 A;  1D6Y A;  3M74 A;  3TY1 A;  2V8K A;  2GH4 A;  4LIX A;  1X1H A;  1NS8 A;  3WIR A;  2HTB A;  2PMV A;  1HM3 A;  3LOY A;  3DSV B;  3DX3 A;  3DSW B;  1AVK A;  4ZRP A;  3LZ9 A;  4Q88 A;  2H6I B;  4D4A A;  3BUQ A;  3IMH A;  2CIR A;  1SQC A;  1QX1 A;  2RI9 A;  1LXM A;  1K1X A;  3DX1 A;  1K1Y A;  1W5Z A;  3VSN A;  1GLM A;  1X1J A;  2YFN A;  1C3D A;  2ONH A;  3CIH A;  3NJX A;  2JF4 A;  4OK2 A;  2ZL8 A;  3PYB A;  3SDR A;  3DRA B;  1DCE B;  2XWJ B;  4FNP A;  1KSI A;  1O7D D;  3I3E A;  1H54 A;  3QFZ A;  5ILZ A;  1FT1 B;  3E6U A;  5DGR A;  1F9O A;  5E2J A;  1RW9 A;  3QXQ A;  3D5R A;  2A73 B;  2WVX B;  3OB8 A;  5ILJ A;  3ACT A;  4AYO A;  3SDT A;  1JZ4 A;  1HCU A;  3HII A;  4FNS A;  2OOV C;  3ANK A;  4GL3 A;  3CZJ A;  2G0D A;  3WFA A;  1O6Q A;  5FO9 B;  1SO0 A;  1N20 A;  3BLC A;  3I3B A;  3NJV A;  4LNB B;  1G9J A;  1H3A A;  1FP3 A;  1V5C A;  1PU4 A;  1NSU A;  3BS6 A;  1HM2 A;  5EAU A;  1F4H A;  4M76 A;  2WCO A;  3QG0 A;  3SDU A;  3PZ2 B;  3P5P A;  1N1Z A;  3EJQ A;  4F13 A;  3PQI A;  2BRV X;  1IVU A;  2GOX A;  1W4N A;  2WW1 A;  1N23 A;  1JS4 A;  2WGQ A;  2WW2 A;  3BVT A;  3I3D A;  3T09 A;  4K35 A;  4TTG A;  1HXC A;  1RQ5 A;  3DX4 A;  2FUZ A;  4J5T A;  1L7K A;  2F7P A;  3WIW A;  2RGK A;  2WMF A;  4MBG B;  4RNL A;  3EQA A;  3KII A;  1SA5 B;  3BUP A;  4AYQ A;  1S64 B;  1NS0 A;  1RWA A;  3NBB A;  5IKH A;  3ACS A;  2F1B A;  4AYR A;  1CLC A; 
#chains in the Genus database with same CATH homology
 1LF9 A;  4DUX A;  4E1Y A;  1W3Y A;  4MMH A;  4OZV A;  4D6D A;  5E1Q A;  1JZ5 A;  1NSX A;  1RWH A;  1MMY A;  1OJN A;  2WW0 A;  1UG9 A;  1MMZ A;  3J7H A;  1C82 A;  2XHN A;  4MMI A;  2E22 A;  3IAQ A;  3VD3 A;  4D6C A;  4D6E A;  2WVY A;  1YQ2 A;  3SEP A;  2D73 A;  1NKG A;  3T0A A;  5A1A A;  3VD5 A;  1RWC A;  2WMJ A;  4OJZ A;  4D6H A;  4AQ0 A;  1ULV A;  1RWF A;  4NEI A;  1F4A A;  2BRW A;  2Q1F A;  3E7J A;  2JKE A;  3T2O A;  1NS4 A;  4D6I A;  1JZ3 A;  1OJP A;  3VDC A;  3NNB A;  4OZW A;  2WVZ A;  3T0D A;  2WZS A;  3E80 A;  3MV1 1;  3E1F 1;  1JZ6 A;  1NSS A;  1PX3 A;  1YGA A;  3TY1 A;  2E24 A;  3Q1N A;  1NS8 A;  1X1H A;  2HTB A;  4DUW A;  1HM3 A;  1N7P A;  2WMI A;  1NSM A;  1SNZ A;  1LUR A;  1NSR A;  3DYM A;  1F9G A;  2JKA A;  4F10 A;  2JKP A;  3MUY 1;  3IMH A;  1X1I A;  4BZG A;  2CIR A;  5JMD A;  1HMU A;  3VSM A;  2WMI B;  1N7R A;  1LXM A;  1K1X A;  3VDB A;  1K1Y A;  2WMK A;  3VD7 A;  2WVX A;  3VSN A;  3AFL A;  1X1J A;  1MMU A;  2FUQ A;  3T2Q A;  1Z45 A;  1HMW A;  3NJX A;  1K1W A;  4OK2 A;  2ZQ0 A;  4D72 A;  3VD4 A;  1JYN A;  4OK4 A;  3T0B A;  1N7N A;  1JZ2 A;  1JZ8 A;  3K25 A;  3I3E A;  1L7J A;  2CIS A;  4BZE A;  1HN1 A;  4D6J A;  4D71 A;  1F1S A;  1HV6 A;  1J0N A;  1HN0 A;  1RW9 A;  3A24 A;  3OB8 A;  2WVX B;  1JYW A;  1TXK A;  2BRP A;  1MN0 A;  1JZ4 A;  1QAZ A;  2WDA A;  4D6F A;  2WW3 A;  3CZJ A;  3OBA A;  3WFA A;  4BZF A;  1N7O A;  1SO0 A;  3BLC A;  3I3B A;  3NJV A;  1OJM A;  1JZ7 A;  1NSZ A;  1NSU A;  3BS6 A;  1NSV A;  1J0M A;  1HM2 A;  3VDA A;  1F4H A;  2WCO A;  3DEC A;  4FNV A;  1PX4 A;  1RWG A;  3IAP A;  1NS7 A;  3NRE A;  3VD9 A;  1OJO A;  1MMX A;  4F13 A;  3BGA A;  2BRV X;  3DCD A;  3MWX A;  2WW1 A;  2WW2 A;  2XSG A;  1I8Q A;  3I3D A;  1EGU A;  3T09 A;  4DUV A;  1NS2 A;  5JMF A;  4TTG A;  1JOV A;  4BZH A;  2X03 A;  1L7K A;  4J5T A;  1N7Q A;  3MV0 1;  3DYO A;  3WVF A;  3DYP A;  2WMF A;  4RNL A;  3T2P A;  1CB8 A;  2HTA A;  2WMG A;  4D6G A;  3OS7 A;  1JYX A;  1LOH A;  2WMH A;  1LF6 A;  1NS0 A;  1RWA A;  3NFV A;  2FUT A;  3T08 A;  2ZXQ A;  1JYV A;  3ECQ A;  3MUZ 1;  3A0O A;  1LXK A;  2CIQ A;  1DP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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