2X03A

The x-ray structure of the streptomyces coelicolor a3 chondroitin ac lyase y253a mutant
Total Genus 249
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
249
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTAGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords PUTATIVE SECRETED LYASE
publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces coelicolor
total genus 249
structure length 742
sequence length 742
chains with identical sequence B
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2x03A01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2x03A03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2x03A02
2CIRA 2E22A 1MMUA 3AFLA 2CIQA 3VD9A 4F10A 1MMYA 1JYXA 4TTGA 3I3EA 1NS0A 4MMHA 3MV11 2WW0A 1MMZA 1HN0A 5JMFA 1L7KA 3CZJA 3WFAA 4DUXA 1LF9A 3I3DA 3VDAA 4E1YA 4D72A 1YQ2A 1NSXA 3I3BA 4D6JA 3VDCA 3T2QA 1NSUA 3T0BA 2WVXA 2WVZA 1CB8A 1NKGA 5E1QA 4DUWA 1N7PA 3NFVA 1JOVA 2E24A 1K1XA 4OZWA 2CISA 2JKAA 3A0OA 4D6HA 1JZ6A 1X1HA 1NS8A 1F4AA 2JKEA 2WVXB 3BGAA 1JZ3A 4DUVA 1N7QA 1J0NA 2BRPA 1N7OA 1SO0A 1RWAA 1JYWA 2WDAA 1JYVA 1RWHA 2BRVX 1LOHA 4OZVA 1HN1A 1JZ7A 3VSNA 4OK4A 3OB8A 3T08A 3J7HA 1NSZA 3E1F1 3K25A 2WZSA 4BZGA 3MUY1 1K1YA 1L7JA 1X1JA 4OJZA 3T09A 1NSMA 1EGUA 1OJOA 1HMWA 1RWFA 4MMIA 2HTAA 1JZ2A 1JZ8A 3IMHA 2WMJA 2WW1A 1RW9A 1TXKA 1MN0A 1N7RA 3A24A 2WMFA 4D6IA 1DP0A 1JZ5A 2X03A 3VD7A 2Q1FA 4D6EA 3ECQA 1F4HA 3T2OA 4OK2A 2FUQA 3DYMA 2JKPA 1Z45A 1OJMA 2ZQ0A 1F9GA 3NREA 3MV01 3VDBA 3NNBA 4D6GA 2WW2A 1MMXA 1X1IA 3DYPA 1YGAA 2WVYA 1LXMA 2HTBA 2XSGA 3DECA 1NSVA 5JMDA 3OS7A 3OBAA 3T0DA 2WMKA 1QAZA 3T0AA 3DYOA 4D6FA 1PX4A 1JYNA 1RWCA 1F1SA 1OJNA 1LURA 3T2PA 1I8QA 3VSMA 4D6DA 1NS2A 3VD5A 1HM3A 4D71A 4RNLA 1HMUA 2WMIA 1NSRA 3VD3A 3VD4A 1LXKA 1ULVA 3Q1NA 4FNVA 2FUTA 3IAPA 4BZFA 3DCDA 3MWXA 4AQ0A 1NS4A 2XHNA 2BRWA 3NJVA 1JZ4A 1HV6A 2WMIB 2WMGA 1OJPA 1NSSA 1LF6A 3NJXA 1RWGA 2D73A 2WCOA 1SNZA 4BZEA 4D6CA 1NS7A 2ZXQA 4NEIA 1N7NA 3E80A 1C82A 2WMHA 1HM2A 1PX3A 3MUZ1 4BZHA 1UG9A 2WW3A 3SEPA 1J0MA 1W3YA 3IAQA 5A1AA 3E7JA 4F13A 1K1WA
chains in the Genus database with same CATH superfamily
3M01A 3DX2A 3WIQA 3AFLA 1N95B 1MMYA 1JYXA 2GH4A 3I3EA 1FAEA 2D8LA 2CWUA 4MMHA 3BVVA 3MV11 4FNQA 3QXFA 2PNCA 1LVNA 1DCEB 1WU5A 1TN8B 3E73A 3QRYA 1KREA 3VDAA 4YCRA 3WA3A 4YDEB 3BVWA 1YQ2A 2OQEC 3G4FA 1XWQA 3S4BA 1W6GA 3M75A 3SXXA 1CB8A 1NI1B 5GW7A 3WC3A 4C1SA 3VW5A 4D6HA 1H35A 1D6UA 1JRQA 2CQSA 3CV5A 1H54A 4FXKB 2BRPA 1N94B 1N7OA 2DROA 3PZ4B 4FJQA 4KKIA 3M78A 1IVUA 3HIIA 1SA4B 2F18A 4K3AA 1JYVA 4GL3A 1KS8A 2XN1A 1LOHA 1TQSA 1N9EA 1JZ7A 5IL8A 3VSNA 3ANKA 3X40A 3HXCB 2WYHA 3EJPA 1WU6A 3EU5B 5DGQA 2YFOA 3X3ZA 1V5DA 3KQ4A 3SDRA 2WZSA 2R2LB 3H7LA 1FT1B 3DX0A 2XWJB 5E2JA 2OOVA 2BT3A 3PZ2B 1X81B 2RI8A 5FO7B 4DUXA 3RSYA 3OXUA 1W6JA 2W0QA 2DRSA 1UMPA 3N0FA 1JZ2A 1W4NA 2YFNA 3IMHA 2WW1A 2EAEA 2JF4A 1TXKA 2B39A 3E34B 4EV2A 4ZH1A 1N7RA 1SQCA 4YDOB 3A24A 3ACTA 1JZ5A 1V7VA 3P5PA 3N9HA 1F4HA 3T2OA 5IK6A 1Z45A 1IVXA 2WW2A 1YGAA 1XWTA 2P0VA 3E30B 4D1IA 1LXMA 3OS7A 3DECA 3LZ9A 1QAZA 5ILKA 3Q79B 1PX4A 4D4CA 1R34A 3Q7AB 1GA2A 4GTTB 1LURA 1N9AB 2B4FA 4FXGB 3KSLB 1HM3A 4D71A 1O79A 1FBOA 4M76A 1ULVA 1TU5A 3GZKA 2FUTA 2RI9A 2KXRA 1VD5A 4JJJA 4D8OA 3ANJA 1HZFA 4EHMB 3MWXA 2EABA 4V1SA 1WU4A 5EASA 2WMGA 4QT9A 3UD2A 4LNGB 4DLQA 2F6DA 1LF6A 4KFDA 5JPMB 5DHIA 3DDGA 4GTSB 5EAUA 4KFFA 1EKMA 2JJBA 2E2UA 1C82A 2FV0A 3D3IA 3QSPA 3P5RA 3BUPA 4FUSA 1W3YA 3E32B 4GTOB 3E7JA 4F13A 2V8KA 4KKJA 4XUVA 2G0DA 1MMUA 2A8ZA 3WIWA 5FO9B 3X3XA 3VD9A 3PZ3B 1RJOA 1FPPB 3QG0A 2FUZA 5M7IA 1O1TB 3WFAA 5JMFA 4L6XA 2BB6A 4BTWA 2WOHA 3KSQB 2NVPA 3VXDA 2XWBB 3WUXA 3I3DA 2FV1A 3MPHA 4K35A 3RX8A 4D72A 1N22A 3E33B 2AHFA 1HTYA 4D4DA 3AFJA 4TXTA 1CEMA 3QXQA 1TQTA 1N24A 2PMVA 2WINB 2WVZA 1QALA 4DUWA 1JOVA 1TNYB 2J5CA 1JCQB 2XFGA 3DX4A 1X1HA 1LTXB 2WVXB 1IS9A 3BGAA 3EJRA 3X42A 4MBGB 5GZKA 1J0NA 1UT9A 4GTMB 1H14A 4DI5A 3DX1A 1JYWA 2NOJA 3QPFA 3S4CA 1HX9A 1RWHA 1XW2A 4OZVA 1LD8B 3SDTA 4WVAA 1DL2A 3OB8A 1KSCA 3DSXB 2FBAA 3M02A 1QAFA 3K11A 2OW7A 1TN6B 4Q88A 2BB5A 4BTYA 3BLCA 3DRAB 3DPYB 3X41A 3Q7FB 1EGUA 1US1A 2ZZRA 4ZRQA 1V7WA 3EUVB 1H13A 2RDYA 1MZCB 2CWTA 2HTAA 2WMJA 1RW9A 1H3BA 1WMOA 1MN0A 1O6HA 3AMOB 2AHGA 3W7WA 1WMPA 1L2AA 4D6IA 2X03A 1KFGA 1QWNA 2Q1FA 2CFWA 2OOVC 3VD7A 3SAEA 3DYMA 3VDBA 1CLCA 3S4DA 1G6IA 3SDUA 5FOBB 2DRQA 5CA3A 3DYPA 3Q78B 1D8DB 3S4AA 1O7DD 2F1BA 2XQWA 1F9DA 3HIGA 1GHQA 2CFLA 3G6JB 5ILJA 2H6FB 1O1SB 2WMKA 1KZOB 3D4YA 2E2VA 1X9DA 3WKGA 1F1SA 4CJ1A 5JPNB 1UI7A 3VSMA 3H2WA 5CD2A 3BS6A 2ZIRB 1O5MB 5DHKA 1FP3A 1H12A 4DODA 2AFAA 2WMIA 1NSRA 3MI6A 3VD3A 3VD4A 1LXKA 5ILDA 3Q1NA 4FNVA 3QWTA 3G4DA 4BZFA 4BOKA 2QNOA 4AQ0A 4CE7A 1IVWA 5ILHA 1NS4A 1H39A 2BRWA 3WIRA 3BLBA 4LNVA 3NBBA 1RWGA 3M73A 1SNZA 1AV4A 2CFDA 3WKHA 5GY3A 5IKHA 1S63B 1IA7A 4L9PB 1TNUB 1N7NA 1D8EB 1R76A 2A73B 5M7YA 3SFXB 5ILIA 2WMHA 3D50A 1V7XA 1FO2A 3Q75B 5IKAA 3QR8A 1WMNA 2WW3A 3M76A 1KWFA 1TNBB 2YX9A 1R33A 1IVVA 3W5MA 1K1WA 3DSSB 1N4RB 2E22A 3M00A 3DSVB 3D51A 3M72A 4TF4A 1QSJA 2VN4A 3WA2X 4KTPA 1PU4A 4WU0A 3M7LA 4DLOA 2WW0A 3QFZA 2GOXA 3CZJA 3X17A 5IL3A 4Q2BA 3OEDA 4WVCA 3D52A 2ONGA 2WOFA 2Y73A 1LD7B 2YIKA 1NSXA 2ONHA 2C11A 3T2QA 1RKYA 5KKBA 2G02A 1NSUA 4ZRPA 3T0BA 3KLSA 3DDFA 1QQFA 1D6ZA 1N7PA 3NFVA 2E24A 1K1XA 4OZWA 2WO0A 3BUQA 2BEDB 2JKEA 1O6RA 1JZ3A 3ON6A 3SDQA 5IM1A 2F7PA 3ALAA 3U7VA 4ONTA 5C05A 1RWAA 3QFYA 1KRFA 1SPUA 1H37A 4J5TA 3K7XA 2BRVX 3PYBA 4OK4A 3T08A 2OW6A 3F59A 2WY8A 3J7HA 4FNSA 3P2CA 3DSWB 3E1F1 3M77A 3K25A 2ALWA 4BZGA 1IU7A 3Q73B 3GT5A 2WIIB 3CU7A 3QDEA 1K1YA 1SIHA 1N1BA 3WVFA 4OJZA 2WY7A 3W7XA 2V8IA 1RWFA 3RRSA 2DRRA 1GXOA 3T0UA 3SQCA 2CQTA 2ZISB 4ZG8A 3M7BA 3QT9A 4L0GA 3RX5A 4AYOA 2WMFA 1DP0A 3C72B 1SA5B 2JG0A 1D6YA 2I07B 3DSUB 3M7EA 4OK2A 3E6UA 3SFYB 1W7CA 1F9GA 1GAHA 2JKPA 3D4ZA 3NREA 1TQUA 2F7QA 3HI7A 5IK9A 2H6HB 3CIHA 3NNBA 4D6GA 2F1AA 1GLMA 2EADA 4AYPA 1MMXA 2WVYA 1JS4A 1QWUA 3OBAA 1TN7B 3RJ3A 5JMDA 1AVLA 1IQYA 1N4QB 3DYOA 3ANIA 1TNZB 2V3PA 3GLYA 3EJQA 3PGBA 1W6KA 5KBPA 2WYNA 2ZBLA 3T2PA 4D6DA 3BVUA 4RNLA 2CWVA 1HMUA 1N23A 3KIIA 2E2TA 4GTRB 4GTPB 3IAPA 2GZ6A 2D1WA 2SQCA 2XHNA 4LIXA 5FO8B 1O6QA 1K72A 1HV6A 1GXNA 1HXAA 1KKTA 3HXBB 3EJTA 4EL8A 1OJPA 1N20A 3NJXA 2D73A 4BZEA 4KFEA 5DGRA 4FNRA 2Z07A 2CG1A 4D6CA 2ZXQA 4NEIA 4MU9A 1IQXA 3LVTA 1HCUA 3E80A 4Z4LA 3NBJA 2C10A 3MUZ1 1JCRB 4BZHA 1GAIA 1UG9A 4WVBA 5AGDA 1J0MA 1A2VA 3X3YA 3QT3A 3WKFA 2CFKA 3IAQA 5A1AA 2OQEA 2H6GB 2CIRA 3W5NA 2CIQA 1OACA 4F10A 4TTGA 1SIIA 3K5TA 4ZH5A 1NS0A 1HWWA 1MMZA 1HN0A 1V5CA 1L7KA 1LF9A 5EATA 4E1YA 3I3BA 1TQWA 1G9GA 4D6JA 3SX1A 3VDCA 1PS3A 2WVXA 1W5ZA 1KZPB 1NKGA 5E1QA 1W2ZA 1FCEA 2D5JA 1N4SB 1TF4A 2EACA 2CISA 4Z4JA 3A0OA 3WKIA 2JKAA 3TF4A 2XN2A 1JZ6A 4GAXA 3N0GA 1F4AA 1NS8A 3HXDB 3ACSA 1F9OA 4FNTA 4DUVA 1H3AA 1N7QA 3H3KA 2FYVA 1FO3A 3KBTC 1SO0A 3W7TA 2WDAA 1HN1A 3M71A 3EJUA 3A3VA 3SDVA 1NSZA 1NXCA 1TNOB 4LNBB 3EU8A 2OKXA 3MUY1 5MEHA 5ILZA 1W6CA 1H3CA 4V1RA 1NC5A 3S9VA 3CZSA 3DSTB 3CZNA 1KSDA 1X1JA 2H6IB 1L7JA 3T09A 3AMOA 1NSMA 1OJOA 1HMWA 4MMIA 2F7RA 1JZ8A 4UFCA 1FMIA 3BUBA 3W7SA 3KBUC 2XN0A 1NL4B 3EZ8A 2CG0A 5IK0A 4D6EA 3ECQA 3T0DA 2FUQA 3MV01 1OJMA 2ZQ0A 1RQ5A 4GTQB 4CJ0A 1QBQB 1DOGA 1G9JA 1L1YA 3UD1A 1HXCA 4D4BA 1FBWA 1X1IA 3W7UA 4FNUA 1HXGA 5ILYA 2CFGA 2BBCA 1O1RB 3PYAA 4BTXA 1G87A 3M74A 2HTBA 2WYIA 2XSGA 1NSVA 4RNQA 1FT2B 3RX7A 3BUDA 3LOYA 3T0AA 3EQAA 4D6FA 3BVXA 1JYNA 1RWCA 3HXFB 1KSIA 1OJNA 3T33A 1QAKA 4GTVB 1I8QA 2ZL8A 2PN5A 5CZLA 1S64B 1NS2A 3VD5A 3HXEB 2Y74A 2WGQA 3BVTA 4D4AA 1GSZA 1IA6A 3E37B 1AGMA 4DOEA 1H36A 1HXKA 3DCDA 3NJVA 4D94A 2VN7A 1JZ4A 3RENA 2WMIB 1JCSB 1GXMA 3M7CA 3PMMA 4D1JA 1NSSA 2F0YB 2V3NA 2V8JA 2WCOA 3D5RA 4AYQA 3PQIA 1AYXA 3EJSA 1NS7A 3D5SA 4FNPA 1PX3A 1HM2A 1N21A 3DX3A 1C3DA 3BUIA 1N1ZA 4BOJA 4KTRA 2RGKA 1QX1A 1DYUA 4AYRA 1UI8A 3PZ1B 1AVKA 3KN4A 3SEPA 1WZZA 4EV5A 2IEJB 3TY1A 2KXSA 1TQVA 1N4PB 2F7OA
chains in the Genus database with same CATH topology
2CIRA 2E22A 1MMUA 3AFLA 2CIQA 3VD9A 4F10A 1MMYA 1JYXA 4TTGA 3I3EA 1NS0A 4MMHA 3MV11 2WW0A 1MMZA 1HN0A 5JMFA 1L7KA 3CZJA 3WFAA 4DUXA 1LF9A 3I3DA 3VDAA 4E1YA 4D72A 1YQ2A 1NSXA 3I3BA 4D6JA 3VDCA 3T2QA 1NSUA 3T0BA 2WVXA 2WVZA 1CB8A 1NKGA 5E1QA 4DUWA 1N7PA 3NFVA 1JOVA 2E24A 1K1XA 4OZWA 2CISA 2JKAA 3A0OA 4D6HA 1JZ6A 1X1HA 1NS8A 1F4AA 2JKEA 2WVXB 3BGAA 1JZ3A 4DUVA 1N7QA 1J0NA 2BRPA 1N7OA 1SO0A 1RWAA 1JYWA 2WDAA 1JYVA 1RWHA 4J5TA 2BRVX 1LOHA 4OZVA 1HN1A 1JZ7A 3VSNA 4OK4A 3OB8A 3T08A 3J7HA 1NSZA 3E1F1 3K25A 2WZSA 4BZGA 3MUY1 1K1YA 3BLCA 1L7JA 1X1JA 4OJZA 3T09A 3WVFA 1NSMA 1EGUA 1OJOA 1HMWA 1RWFA 4MMIA 2HTAA 1JZ2A 1JZ8A 3IMHA 2WMJA 2WW1A 1RW9A 1TXKA 1MN0A 1N7RA 3A24A 2WMFA 4D6IA 1DP0A 1JZ5A 2X03A 3VD7A 2Q1FA 4D6EA 3ECQA 1F4HA 3T2OA 4OK2A 2FUQA 3DYMA 2JKPA 1Z45A 1OJMA 2ZQ0A 1F9GA 3NREA 3MV01 3VDBA 3NNBA 4D6GA 2WW2A 1MMXA 1X1IA 3DYPA 1YGAA 2WVYA 1LXMA 2HTBA 2XSGA 3DECA 1NSVA 5JMDA 3OS7A 3OBAA 3T0DA 2WMKA 1QAZA 3T0AA 3DYOA 4D6FA 1PX4A 1JYNA 1RWCA 1F1SA 1OJNA 1LURA 3T2PA 1I8QA 3BS6A 3VSMA 4D6DA 1NS2A 3VD5A 1HM3A 4D71A 4RNLA 1HMUA 2WMIA 1NSRA 3VD3A 3VD4A 1LXKA 1ULVA 3Q1NA 4FNVA 2FUTA 3IAPA 4BZFA 3DCDA 3MWXA 4AQ0A 1NS4A 2XHNA 2BRWA 3NJVA 1JZ4A 1HV6A 2WMIB 2WMGA 1OJPA 1NSSA 1LF6A 3NJXA 1RWGA 2D73A 2WCOA 1SNZA 4BZEA 4D6CA 1NS7A 2ZXQA 4NEIA 1N7NA 3E80A 1C82A 2WMHA 1HM2A 1PX3A 3MUZ1 4BZHA 1UG9A 2WW3A 3SEPA 1J0MA 1W3YA 3IAQA 5A1AA 3TY1A 3E7JA 4F13A 1K1WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CIR A;  2E22 A;  1MMU A;  3AFL A;  2CIQ A;  3VD9 A;  4F10 A;  1MMY A;  1JYX A;  4TTG A;  3I3E A;  1NS0 A;  4MMH A;  3MV1 1;  2WW0 A;  1MMZ A;  1HN0 A;  5JMF A;  1L7K A;  3CZJ A;  3WFA A;  4DUX A;  1LF9 A;  3I3D A;  3VDA A;  4E1Y A;  4D72 A;  1YQ2 A;  1NSX A;  3I3B A;  4D6J A;  3VDC A;  3T2Q A;  1NSU A;  3T0B A;  2WVX A;  2WVZ A;  1CB8 A;  1NKG A;  5E1Q A;  4DUW A;  1N7P A;  3NFV A;  1JOV A;  2E24 A;  1K1X A;  4OZW A;  2CIS A;  2JKA A;  3A0O A;  4D6H A;  1JZ6 A;  1X1H A;  1NS8 A;  1F4A A;  2JKE A;  2WVX B;  3BGA A;  1JZ3 A;  4DUV A;  1N7Q A;  1J0N A;  2BRP A;  1N7O A;  1SO0 A;  1RWA A;  1JYW A;  2WDA A;  1JYV A;  1RWH A;  2BRV X;  1LOH A;  4OZV A;  1HN1 A;  1JZ7 A;  3VSN A;  4OK4 A;  3OB8 A;  3T08 A;  3J7H A;  1NSZ A;  3E1F 1;  3K25 A;  2WZS A;  4BZG A;  3MUY 1;  1K1Y A;  1L7J A;  1X1J A;  4OJZ A;  3T09 A;  1NSM A;  1EGU A;  1OJO A;  1HMW A;  1RWF A;  4MMI A;  2HTA A;  1JZ2 A;  1JZ8 A;  3IMH A;  2WMJ A;  2WW1 A;  1RW9 A;  1TXK A;  1MN0 A;  1N7R A;  3A24 A;  2WMF A;  4D6I A;  1DP0 A;  1JZ5 A;  2X03 A;  3VD7 A;  2Q1F A;  4D6E A;  3ECQ A;  1F4H A;  3T2O A;  4OK2 A;  2FUQ A;  3DYM A;  2JKP A;  1Z45 A;  1OJM A;  2ZQ0 A;  1F9G A;  3NRE A;  3MV0 1;  3VDB A;  3NNB A;  4D6G A;  2WW2 A;  1MMX A;  1X1I A;  3DYP A;  1YGA A;  2WVY A;  1LXM A;  2HTB A;  2XSG A;  3DEC A;  1NSV A;  5JMD A;  3OS7 A;  3OBA A;  3T0D A;  2WMK A;  1QAZ A;  3T0A A;  3DYO A;  4D6F A;  1PX4 A;  1JYN A;  1RWC A;  1F1S A;  1OJN A;  1LUR A;  3T2P A;  1I8Q A;  3VSM A;  4D6D A;  1NS2 A;  3VD5 A;  1HM3 A;  4D71 A;  4RNL A;  1HMU A;  2WMI A;  1NSR A;  3VD3 A;  3VD4 A;  1LXK A;  1ULV A;  3Q1N A;  4FNV A;  2FUT A;  3IAP A;  4BZF A;  3DCD A;  3MWX A;  4AQ0 A;  1NS4 A;  2XHN A;  2BRW A;  3NJV A;  1JZ4 A;  1HV6 A;  2WMI B;  2WMG A;  1OJP A;  1NSS A;  1LF6 A;  3NJX A;  1RWG A;  2D73 A;  2WCO A;  1SNZ A;  4BZE A;  4D6C A;  1NS7 A;  2ZXQ A;  4NEI A;  1N7N A;  3E80 A;  1C82 A;  2WMH A;  1HM2 A;  1PX3 A;  3MUZ 1;  4BZH A;  1UG9 A;  2WW3 A;  3SEP A;  1J0M A;  1W3Y A;  3IAQ A;  5A1A A;  3E7J A;  4F13 A;  1K1W A; 
#chains in the Genus database with same CATH topology
 3M01 A;  3DX2 A;  3WIQ A;  3AFL A;  1N95 B;  1MMY A;  1JYX A;  2GH4 A;  3I3E A;  1FAE A;  2D8L A;  2CWU A;  4MMH A;  3BVV A;  3MV1 1;  4FNQ A;  3QXF A;  2PNC A;  1LVN A;  1DCE B;  1WU5 A;  1TN8 B;  3E73 A;  3QRY A;  1KRE A;  3VDA A;  4YCR A;  3WA3 A;  4YDE B;  3BVW A;  1YQ2 A;  2OQE C;  3G4F A;  1XWQ A;  3S4B A;  1W6G A;  3M75 A;  3SXX A;  1CB8 A;  1NI1 B;  5GW7 A;  3WC3 A;  4C1S A;  3VW5 A;  4D6H A;  1H35 A;  1D6U A;  1JRQ A;  2CQS A;  3CV5 A;  1H54 A;  4FXK B;  2BRP A;  1N94 B;  1N7O A;  2DRO A;  3PZ4 B;  4FJQ A;  4KKI A;  3M78 A;  1IVU A;  3HII A;  1SA4 B;  2F18 A;  4K3A A;  1JYV A;  4GL3 A;  1KS8 A;  2XN1 A;  1LOH A;  1TQS A;  1N9E A;  1JZ7 A;  5IL8 A;  3VSN A;  3ANK A;  3X40 A;  3HXC B;  2WYH A;  3EJP A;  1WU6 A;  3EU5 B;  5DGQ A;  2YFO A;  3X3Z A;  1V5D A;  3KQ4 A;  3SDR A;  2WZS A;  2R2L B;  3H7L A;  1FT1 B;  3DX0 A;  2XWJ B;  5E2J A;  2OOV A;  2BT3 A;  3PZ2 B;  1X81 B;  2RI8 A;  5FO7 B;  4DUX A;  3RSY A;  3OXU A;  1W6J A;  2W0Q A;  2DRS A;  1UMP A;  3N0F A;  1JZ2 A;  1W4N A;  2YFN A;  3IMH A;  2WW1 A;  2EAE A;  2JF4 A;  1TXK A;  2B39 A;  3E34 B;  4EV2 A;  4ZH1 A;  1N7R A;  1SQC A;  4YDO B;  3A24 A;  3ACT A;  1JZ5 A;  1V7V A;  3P5P A;  3N9H A;  1F4H A;  3T2O A;  5IK6 A;  1Z45 A;  1IVX A;  2WW2 A;  1YGA A;  1XWT A;  2P0V A;  3E30 B;  4D1I A;  1LXM A;  3OS7 A;  3DEC A;  3LZ9 A;  1QAZ A;  5ILK A;  3Q79 B;  1PX4 A;  4D4C A;  1R34 A;  3Q7A B;  1GA2 A;  4GTT B;  1LUR A;  1N9A B;  2B4F A;  4FXG B;  3KSL B;  1HM3 A;  4D71 A;  1O79 A;  1FBO A;  4M76 A;  1ULV A;  1TU5 A;  3GZK A;  2FUT A;  2RI9 A;  2KXR A;  1VD5 A;  4JJJ A;  4D8O A;  3ANJ A;  1HZF A;  4EHM B;  3MWX A;  2EAB A;  4V1S A;  1WU4 A;  5EAS A;  2WMG A;  4QT9 A;  3UD2 A;  4LNG B;  4DLQ A;  2F6D A;  1LF6 A;  4KFD A;  5JPM B;  5DHI A;  3DDG A;  4GTS B;  5EAU A;  4KFF A;  1EKM A;  2JJB A;  2E2U A;  1C82 A;  2FV0 A;  3D3I A;  3QSP A;  3P5R A;  3BUP A;  4FUS A;  1W3Y A;  3E32 B;  4GTO B;  3E7J A;  4F13 A;  2V8K A;  4KKJ A;  4XUV A;  2G0D A;  1MMU A;  2A8Z A;  3WIW A;  5FO9 B;  3X3X A;  3VD9 A;  3PZ3 B;  1RJO A;  1FPP B;  3QG0 A;  2FUZ A;  5M7I A;  1O1T B;  3WFA A;  5JMF A;  4L6X A;  2BB6 A;  4BTW A;  2WOH A;  3KSQ B;  2NVP A;  3VXD A;  2XWB B;  3WUX A;  3I3D A;  2FV1 A;  3MPH A;  4K35 A;  3RX8 A;  4D72 A;  1N22 A;  3E33 B;  2AHF A;  1HTY A;  4D4D A;  3AFJ A;  4TXT A;  1CEM A;  3QXQ A;  1TQT A;  1N24 A;  2PMV A;  2WIN B;  2WVZ A;  1QAL A;  4DUW A;  1JOV A;  1TNY B;  2J5C A;  1JCQ B;  2XFG A;  3DX4 A;  1X1H A;  1LTX B;  2WVX B;  1IS9 A;  3BGA A;  3EJR A;  3X42 A;  4MBG B;  5GZK A;  1J0N A;  1UT9 A;  4GTM B;  1H14 A;  4DI5 A;  3DX1 A;  1JYW A;  2NOJ A;  3QPF A;  3S4C A;  1HX9 A;  1RWH A;  1XW2 A;  4OZV A;  1LD8 B;  3SDT A;  4WVA A;  1DL2 A;  3OB8 A;  1KSC A;  3DSX B;  2FBA A;  3M02 A;  1QAF A;  3K11 A;  2OW7 A;  1TN6 B;  4Q88 A;  2BB5 A;  4BTY A;  3BLC A;  3DRA B;  3DPY B;  3X41 A;  3Q7F B;  1EGU A;  1US1 A;  2ZZR A;  4ZRQ A;  1V7W A;  3EUV B;  1H13 A;  2RDY A;  1MZC B;  2CWT A;  2HTA A;  2WMJ A;  1RW9 A;  1H3B A;  1WMO A;  1MN0 A;  1O6H A;  3AMO B;  2AHG A;  3W7W A;  1WMP A;  1L2A A;  4D6I A;  2X03 A;  1KFG A;  1QWN A;  2Q1F A;  2CFW A;  2OOV C;  3VD7 A;  3SAE A;  3DYM A;  3VDB A;  1CLC A;  3S4D A;  1G6I A;  3SDU A;  5FOB B;  2DRQ A;  5CA3 A;  3DYP A;  3Q78 B;  1D8D B;  3S4A A;  1O7D D;  2F1B A;  2XQW A;  1F9D A;  3HIG A;  1GHQ A;  2CFL A;  3G6J B;  5ILJ A;  2H6F B;  1O1S B;  2WMK A;  1KZO B;  3D4Y A;  2E2V A;  1X9D A;  3WKG A;  1F1S A;  4CJ1 A;  5JPN B;  1UI7 A;  3VSM A;  3H2W A;  5CD2 A;  3BS6 A;  2ZIR B;  1O5M B;  5DHK A;  1FP3 A;  1H12 A;  4DOD A;  2AFA A;  2WMI A;  1NSR A;  3MI6 A;  3VD3 A;  3VD4 A;  1LXK A;  5ILD A;  3Q1N A;  4FNV A;  3QWT A;  3G4D A;  4BZF A;  4BOK A;  2QNO A;  4AQ0 A;  4CE7 A;  1IVW A;  5ILH A;  1NS4 A;  1H39 A;  2BRW A;  3WIR A;  3BLB A;  4LNV A;  3NBB A;  1RWG A;  3M73 A;  1SNZ A;  1AV4 A;  2CFD A;  3WKH A;  5GY3 A;  5IKH A;  1S63 B;  1IA7 A;  4L9P B;  1TNU B;  1N7N A;  1D8E B;  1R76 A;  2A73 B;  5M7Y A;  3SFX B;  5ILI A;  2WMH A;  3D50 A;  1V7X A;  1FO2 A;  3Q75 B;  5IKA A;  3QR8 A;  1WMN A;  2WW3 A;  3M76 A;  1KWF A;  1TNB B;  2YX9 A;  1R33 A;  1IVV A;  3W5M A;  1K1W A;  3DSS B;  1N4R B;  2E22 A;  3M00 A;  3DSV B;  3D51 A;  3M72 A;  4TF4 A;  1QSJ A;  2VN4 A;  3WA2 X;  4KTP A;  1PU4 A;  4WU0 A;  3M7L A;  4DLO A;  2WW0 A;  3QFZ A;  2GOX A;  3CZJ A;  3X17 A;  5IL3 A;  4Q2B A;  3OED A;  4WVC A;  3D52 A;  2ONG A;  2WOF A;  2Y73 A;  1LD7 B;  2YIK A;  1NSX A;  2ONH A;  2C11 A;  3T2Q A;  1RKY A;  5KKB A;  2G02 A;  1NSU A;  4ZRP A;  3T0B A;  3KLS A;  3DDF A;  1QQF A;  1D6Z A;  1N7P A;  3NFV A;  2E24 A;  1K1X A;  4OZW A;  2WO0 A;  3BUQ A;  2BED B;  2JKE A;  1O6R A;  1JZ3 A;  3ON6 A;  3SDQ A;  5IM1 A;  2F7P A;  3ALA A;  3U7V A;  4ONT A;  5C05 A;  1RWA A;  3QFY A;  1KRF A;  1SPU A;  1H37 A;  4J5T A;  3K7X A;  2BRV X;  3PYB A;  4OK4 A;  3T08 A;  2OW6 A;  3F59 A;  2WY8 A;  3J7H A;  4FNS A;  3P2C A;  3DSW B;  3E1F 1;  3M77 A;  3K25 A;  2ALW A;  4BZG A;  1IU7 A;  3Q73 B;  3GT5 A;  2WII B;  3CU7 A;  3QDE A;  1K1Y A;  1SIH A;  1N1B A;  3WVF A;  4OJZ A;  2WY7 A;  3W7X A;  2V8I A;  1RWF A;  3RRS A;  2DRR A;  1GXO A;  3T0U A;  3SQC A;  2CQT A;  2ZIS B;  4ZG8 A;  3M7B A;  3QT9 A;  4L0G A;  3RX5 A;  4AYO A;  2WMF A;  1DP0 A;  3C72 B;  1SA5 B;  2JG0 A;  1D6Y A;  2I07 B;  3DSU B;  3M7E A;  4OK2 A;  3E6U A;  3SFY B;  1W7C A;  1F9G A;  1GAH A;  2JKP A;  3D4Z A;  3NRE A;  1TQU A;  2F7Q A;  3HI7 A;  5IK9 A;  2H6H B;  3CIH A;  3NNB A;  4D6G A;  2F1A A;  1GLM A;  2EAD A;  4AYP A;  1MMX A;  2WVY A;  1JS4 A;  1QWU A;  3OBA A;  1TN7 B;  3RJ3 A;  5JMD A;  1AVL A;  1IQY A;  1N4Q B;  3DYO A;  3ANI A;  1TNZ B;  2V3P A;  3GLY A;  3EJQ A;  3PGB A;  1W6K A;  5KBP A;  2WYN A;  2ZBL A;  3T2P A;  4D6D A;  3BVU A;  4RNL A;  2CWV A;  1HMU A;  1N23 A;  3KII A;  2E2T A;  4GTR B;  4GTP B;  3IAP A;  2GZ6 A;  2D1W A;  2SQC A;  2XHN A;  4LIX A;  5FO8 B;  1O6Q A;  1K72 A;  1HV6 A;  1GXN A;  1HXA A;  1KKT A;  3HXB B;  3EJT A;  4EL8 A;  1OJP A;  1N20 A;  3NJX A;  2D73 A;  4BZE A;  4KFE A;  5DGR A;  4FNR A;  2Z07 A;  2CG1 A;  4D6C A;  2ZXQ A;  4NEI A;  4MU9 A;  1IQX A;  3LVT A;  1HCU A;  3E80 A;  4Z4L A;  3NBJ A;  2C10 A;  3MUZ 1;  1JCR B;  4BZH A;  1GAI A;  1UG9 A;  4WVB A;  5AGD A;  1J0M A;  1A2V A;  3X3Y A;  3QT3 A;  3WKF A;  2CFK A;  3IAQ A;  5A1A A;  2OQE A;  2H6G B;  2CIR A;  3W5N A;  2CIQ A;  1OAC A;  4F10 A;  4TTG A;  1SII A;  3K5T A;  4ZH5 A;  1NS0 A;  1HWW A;  1MMZ A;  1HN0 A;  1V5C A;  1L7K A;  1LF9 A;  5EAT A;  4E1Y A;  3I3B A;  1TQW A;  1G9G A;  4D6J A;  3SX1 A;  3VDC A;  1PS3 A;  2WVX A;  1W5Z A;  1KZP B;  1NKG A;  5E1Q A;  1W2Z A;  1FCE A;  2D5J A;  1N4S B;  1TF4 A;  2EAC A;  2CIS A;  4Z4J A;  3A0O A;  3WKI A;  2JKA A;  3TF4 A;  2XN2 A;  1JZ6 A;  4GAX A;  3N0G A;  1F4A A;  1NS8 A;  3HXD B;  3ACS A;  1F9O A;  4FNT A;  4DUV A;  1H3A A;  1N7Q A;  3H3K A;  2FYV A;  1FO3 A;  3KBT C;  1SO0 A;  3W7T A;  2WDA A;  1HN1 A;  3M71 A;  3EJU A;  3A3V A;  3SDV A;  1NSZ A;  1NXC A;  1TNO B;  4LNB B;  3EU8 A;  2OKX A;  3MUY 1;  5MEH A;  5ILZ A;  1W6C A;  1H3C A;  4V1R A;  1NC5 A;  3S9V A;  3CZS A;  3DST B;  3CZN A;  1KSD A;  1X1J A;  2H6I B;  1L7J A;  3T09 A;  3AMO A;  1NSM A;  1OJO A;  1HMW A;  4MMI A;  2F7R A;  1JZ8 A;  4UFC A;  1FMI A;  3BUB A;  3W7S A;  3KBU C;  2XN0 A;  1NL4 B;  3EZ8 A;  2CG0 A;  5IK0 A;  4D6E A;  3ECQ A;  3T0D A;  2FUQ A;  3MV0 1;  1OJM A;  2ZQ0 A;  1RQ5 A;  4GTQ B;  4CJ0 A;  1QBQ B;  1DOG A;  1G9J A;  1L1Y A;  3UD1 A;  1HXC A;  4D4B A;  1FBW A;  1X1I A;  3W7U A;  4FNU A;  1HXG A;  5ILY A;  2CFG A;  2BBC A;  1O1R B;  3PYA A;  4BTX A;  1G87 A;  3M74 A;  2HTB A;  2WYI A;  2XSG A;  1NSV A;  4RNQ A;  1FT2 B;  3RX7 A;  3BUD A;  3LOY A;  3T0A A;  3EQA A;  4D6F A;  3BVX A;  1JYN A;  1RWC A;  3HXF B;  1KSI A;  1OJN A;  3T33 A;  1QAK A;  4GTV B;  1I8Q A;  2ZL8 A;  2PN5 A;  5CZL A;  1S64 B;  1NS2 A;  3VD5 A;  3HXE B;  2Y74 A;  2WGQ A;  3BVT A;  4D4A A;  1GSZ A;  1IA6 A;  3E37 B;  1AGM A;  4DOE A;  1H36 A;  1HXK A;  3DCD A;  3NJV A;  4D94 A;  2VN7 A;  1JZ4 A;  3REN A;  2WMI B;  1JCS B;  1GXM A;  3M7C A;  3PMM A;  4D1J A;  1NSS A;  2F0Y B;  2V3N A;  2V8J A;  2WCO A;  3D5R A;  4AYQ A;  3PQI A;  1AYX A;  3EJS A;  1NS7 A;  3D5S A;  4FNP A;  1PX3 A;  1HM2 A;  1N21 A;  3DX3 A;  1C3D A;  3BUI A;  1N1Z A;  4BOJ A;  4KTR A;  2RGK A;  1QX1 A;  1DYU A;  4AYR A;  1UI8 A;  3PZ1 B;  1AVK A;  3KN4 A;  3SEP A;  1WZZ A;  4EV5 A;  2IEJ B;  3TY1 A;  2KXS A;  1TQV A;  1N4P B;  2F7O A; 
#chains in the Genus database with same CATH homology
 2CIR A;  2E22 A;  1MMU A;  3AFL A;  2CIQ A;  3VD9 A;  4F10 A;  1MMY A;  1JYX A;  4TTG A;  3I3E A;  1NS0 A;  4MMH A;  3MV1 1;  2WW0 A;  1MMZ A;  1HN0 A;  5JMF A;  1L7K A;  3CZJ A;  3WFA A;  4DUX A;  1LF9 A;  3I3D A;  3VDA A;  4E1Y A;  4D72 A;  1YQ2 A;  1NSX A;  3I3B A;  4D6J A;  3VDC A;  3T2Q A;  1NSU A;  3T0B A;  2WVX A;  2WVZ A;  1CB8 A;  1NKG A;  5E1Q A;  4DUW A;  1N7P A;  3NFV A;  1JOV A;  2E24 A;  1K1X A;  4OZW A;  2CIS A;  2JKA A;  3A0O A;  4D6H A;  1JZ6 A;  1X1H A;  1NS8 A;  1F4A A;  2JKE A;  2WVX B;  3BGA A;  1JZ3 A;  4DUV A;  1N7Q A;  1J0N A;  2BRP A;  1N7O A;  1SO0 A;  1RWA A;  1JYW A;  2WDA A;  1JYV A;  1RWH A;  4J5T A;  2BRV X;  1LOH A;  4OZV A;  1HN1 A;  1JZ7 A;  3VSN A;  4OK4 A;  3OB8 A;  3T08 A;  3J7H A;  1NSZ A;  3E1F 1;  3K25 A;  2WZS A;  4BZG A;  3MUY 1;  1K1Y A;  3BLC A;  1L7J A;  1X1J A;  4OJZ A;  3T09 A;  3WVF A;  1NSM A;  1EGU A;  1OJO A;  1HMW A;  1RWF A;  4MMI A;  2HTA A;  1JZ2 A;  1JZ8 A;  3IMH A;  2WMJ A;  2WW1 A;  1RW9 A;  1TXK A;  1MN0 A;  1N7R A;  3A24 A;  2WMF A;  4D6I A;  1DP0 A;  1JZ5 A;  2X03 A;  3VD7 A;  2Q1F A;  4D6E A;  3ECQ A;  1F4H A;  3T2O A;  4OK2 A;  2FUQ A;  3DYM A;  2JKP A;  1Z45 A;  1OJM A;  2ZQ0 A;  1F9G A;  3NRE A;  3MV0 1;  3VDB A;  3NNB A;  4D6G A;  2WW2 A;  1MMX A;  1X1I A;  3DYP A;  1YGA A;  2WVY A;  1LXM A;  2HTB A;  2XSG A;  3DEC A;  1NSV A;  5JMD A;  3OS7 A;  3OBA A;  3T0D A;  2WMK A;  1QAZ A;  3T0A A;  3DYO A;  4D6F A;  1PX4 A;  1JYN A;  1RWC A;  1F1S A;  1OJN A;  1LUR A;  3T2P A;  1I8Q A;  3BS6 A;  3VSM A;  4D6D A;  1NS2 A;  3VD5 A;  1HM3 A;  4D71 A;  4RNL A;  1HMU A;  2WMI A;  1NSR A;  3VD3 A;  3VD4 A;  1LXK A;  1ULV A;  3Q1N A;  4FNV A;  2FUT A;  3IAP A;  4BZF A;  3DCD A;  3MWX A;  4AQ0 A;  1NS4 A;  2XHN A;  2BRW A;  3NJV A;  1JZ4 A;  1HV6 A;  2WMI B;  2WMG A;  1OJP A;  1NSS A;  1LF6 A;  3NJX A;  1RWG A;  2D73 A;  2WCO A;  1SNZ A;  4BZE A;  4D6C A;  1NS7 A;  2ZXQ A;  4NEI A;  1N7N A;  3E80 A;  1C82 A;  2WMH A;  1HM2 A;  1PX3 A;  3MUZ 1;  4BZH A;  1UG9 A;  2WW3 A;  3SEP A;  1J0M A;  1W3Y A;  3IAQ A;  5A1A A;  3TY1 A;  3E7J A;  4F13 A;  1K1W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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