2X03A

The x-ray structure of the streptomyces coelicolor a3 chondroitin ac lyase y253a mutant
Total Genus 249
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
249
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTAGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces coelicolor
molecule tags Lyase
molecule keywords PUTATIVE SECRETED LYASE
total genus 249
structure length 742
sequence length 742
chains with identical sequence B
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2x03A01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2x03A03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2x03A02
2D73A 1JZ7A 3CZJA 3IMHA 3VD3A 1NSSA 1PX3A 1OJNA 4OZVA 4DUWA 3SEPA 1I8QA 4OJZA 1OJPA 3NNBA 2WVXA 2WMKA 3DYMA 1JZ2A 1NSMA 5JMFA 1MMYA 2ZQ0A 5A1AA 2E24A 1NKGA 3VD4A 1HMWA 1TXKA 3T09A 4BZEA 4BZFA 3VSMA 4DUXA 2BRVX 3T0DA 3I3BA 1L7KA 3IAPA 1OJMA 1Z45A 2JKEA 2WMFA 3MV01 1UG9A 2WMIA 3NFVA 2HTAA 3OS7A 3T0BA 1HV6A 3T2PA 2Q1FA 2WDAA 1JZ4A 1LF6A 1HN0A 2WVXB 1JYVA 1MMZA 1LXMA 3VSNA 1F4HA 4FNVA 2HTBA 2WW0A 3VD7A 2WVZA 3WFAA 1NS7A 3MUZ1 3BGAA 2WMJA 3DYOA 1RWHA 1MMUA 3ECQA 2WZSA 1F1SA 2WCOA 1LF9A 3MWXA 1C82A 1RW9A 2WW2A 1JOVA 2CIRA 3OBAA 1L7JA 4MMIA 2WMGA 4F13A 2FUQA 4D72A 2ZXQA 4RNLA 1N7QA 1N7PA 1NS4A 3VDAA 4NEIA 1DP0A 5JMDA 4E1YA 1X1IA 4D6EA 1SNZA 3OB8A 3T2OA 3VD5A 3E80A 3VDCA 1N7OA 2WVYA 3T08A 4BZHA 1MN0A 1OJOA 1F9GA 2XSGA 3T2QA 3I3EA 3DECA 1J0NA 1HM2A 4MMHA 4D6IA 1LURA 1JZ3A 1HMUA 3T0AA 1NS0A 4OK4A 2JKAA 2XHNA 1J0MA 2WW1A 1K1YA 4D6CA 1NS2A 4OZWA 4D6JA 4F10A 4D6FA 1JYWA 2WMHA 1X1HA 1YQ2A 1JYXA 1X1JA 1NS8A 1RWGA 1K1XA 3DYPA 1RWCA 2JKPA 2WW3A 1N7RA 1HM3A 3Q1NA 1JZ8A 3AFLA 4OK2A 2E22A 3A0OA 4BZGA 4DUVA 4D6GA 1YGAA 1N7NA 1NSVA 1LXKA 1F4AA 5E1QA 2CIQA 1CB8A 3E1F1 1NSUA 3VDBA 1QAZA 1RWAA 2BRWA 2FUTA 3K25A 3NJXA 4TTGA 1NSRA 1K1WA 1HN1A 1SO0A 3IAQA 3VD9A 3DCDA 1JZ5A 4D71A 3I3DA 1JYNA 2WMIB 4D6HA 1NSZA 1MMXA 3A24A 1EGUA 3E7JA 3NREA 1PX4A 4D6DA 1W3YA 1RWFA 3J7HA 1LOHA 2X03A 2BRPA 3NJVA 3MUY1 3MV11 1ULVA 1JZ6A 2CISA 1NSXA 4AQ0A
chains in the Genus database with same CATH superfamily
1HCUA 3M76A 3CZJA 1NSSA 2WGQA 1OJNA 4OZVA 1I8QA 4OJZA 5M7YA 5IKHA 3BS6A 1IS9A 3Q7FB 1N23A 1AVKA 3LVTA 4CJ1A 5ILJA 5A1AA 2E24A 5ILIA 1UT9A 3SDUA 4BZEA 3ALAA 1L1YA 3E33B 3W7XA 3I3BA 2H6HB 3E6UA 3IAPA 3PZ1B 1OJMA 4RNQA 3X40A 4LNGB 1DCEB 2WMIA 2HTAA 3GZKA 1DYUA 1W7CA 1JCRB 4D4AA 2AHGA 5E2JA 1K72A 3T2PA 3E34B 4L6XA 1HTYA 3M74A 2CFKA 5ILZA 1LF6A 1GAHA 4XUVA 2DROA 2E2TA 1WU6A 1N4QB 1H3AA 2JF4A 3KSQB 3EU5B 3N9HA 2WW0A 1F9OA 2EABA 2WVZA 3BVVA 4CE7A 3DX4A 4FNQA 3VD7A 3WIRA 3F59A 3WC3A 5EATA 2F0YB 1RWHA 3ACSA 3RENA 5GY3A 1TQSA 2F1BA 1LF9A 1O6QA 1WMPA 1WZZA 3EQAA 1C82A 5ILDA 3D5RA 3EUVB 4KTPA 2WW2A 3HIIA 1XW2A 1O79A 1GA2A 3QR8A 4J5TA 1N7QA 2JG0A 1W6JA 4JJJA 1F9DA 4NEIA 1X1IA 4MU9A 2WY7A 3OB8A 3T2OA 1QAKA 5JPMB 3NBJA 1O7DD 3WKHA 1PS3A 2FYVA 3DX1A 4C1SA 4FUSA 1FBWA 1V7XA 1OJOA 3S4DA 4WU0A 3AMOB 4K35A 2CG0A 3KN4A 3QG0A 5AGDA 1W5ZA 3M7CA 3BLBA 3EJPA 1QQFA 2XHNA 1J0MA 3SDQA 1D6YA 4AYRA 4UFCA 4D6JA 1R33A 5CD2A 2YIKA 4D6FA 2BT3A 1X1JA 2FV0A 4GAXA 1NS8A 1RWGA 1TU5A 3KBUC 5FO8B 3DYPA 1O1TB 2WW3A 1N7RA 1GXMA 2OW7A 4OK2A 2CFLA 2F7OA 2C10A 1IA7A 1H3CA 2V8JA 2PNCA 2ALWA 2B4FA 2XN0A 5GW7A 1KZOB 3GT5A 5E1QA 4ZG8A 1CB8A 3D51A 4GTMB 1QAZA 2D8LA 1MZCB 4D8OA 4FXKB 2DRRA 2BB6A 2AFAA 2BRWA 5IL8A 2F7PA 1AGMA 2FUTA 3K25A 4TTGA 1X9DA 3X3XA 5FOBB 1SO0A 3DX3A 1TQWA 5KBPA 1W6GA 2I07B 5EASA 1TNZB 3E73A 2XN2A 3I3DA 3SDTA 4GTVB 4FNSA 3NREA 3LOYA 1W3YA 3RX7A 3BLCA 1EKMA 2X03A 2EADA 3MV11 3RJ3A 1ULVA 3M7EA 4TXTA 1JCQB 1FO2A 1JZ6A 3H7LA 4AQ0A 3EZ8A 1SIHA 4BTXA 3M01A 2D73A 3IMHA 1WU4A 3RRSA 2WYHA 1FMIA 3ACTA 3SEPA 3QT3A 3WA3A 1H39A 3WUXA 1OJPA 3HXDB 2WVXA 4FNRA 1TNYB 3T33A 3PZ2B 5KKBA 1OACA 3DYMA 1W6KA 1SQCA 2GZ6A 2VN4A 3TF4A 5EAUA 5JMFA 3W5MA 1MMYA 1JZ2A 4Q88A 5IK6A 2H6IB 3CZNA 1IQYA 3KIIA 1UMPA 3QSPA 3VD4A 2CWTA 1TXKA 4BZFA 5JPNB 1C3DA 2BRVX 3DX2A 1KRFA 1N20A 2A73B 1Z45A 5ILYA 3WKFA 3OS7A 3U7VA 3M02A 2R2LB 1GHQA 1TQTA 2WDAA 3M78A 5DGQA 1TQUA 1HXAA 3W7TA 3WKGA 1HN0A 2V3PA 5ILKA 1JYVA 1G9GA 1MMZA 3A3VA 3D3IA 3PMMA 2BB5A 4LIXA 1TN6B 4EHMB 2CG1A 3QPFA 2Z07A 2AHFA 2ZBLA 4FNVA 3WFAA 1NS7A 3BGAA 5GZKA 2G02A 1TF4A 2F6DA 2FBAA 1V5CA 3K11A 4V1SA 2YFNA 1FPPB 2WZSA 3SX1A 2SQCA 4Z4LA 1D8DB 5M7IA 4FNTA 3N0FA 3MWXA 3DDGA 4D4BA 3QFYA 2CIRA 4MMIA 1KWFA 4F13A 1QALA 4D72A 3W7SA 2WYNA 3QFZA 1N7PA 3TY1A 3VDAA 1SNZA 1KSCA 1N24A 3CV5A 3S4AA 3VDCA 3BVWA 1IVWA 3DSVB 3KBTC 4BZHA 1MN0A 3W7WA 2FUZA 1O6HA 3T2QA 4YDOB 3D50A 3X3ZA 1QWNA 1J0NA 2CQTA 2XWBB 3PZ4B 4MMHA 1L2AA 1US1A 2OW6A 3PZ3B 1H13A 1NS0A 4QT9A 2G0DA 1GLMA 4KKIA 1N22A 3Q7AB 1WU5A 2WOFA 4BOJA 1SA5B 3S4CA 4KFEA 2WMHA 1YQ2A 3AMOA 2RI9A 2RGKA 1FT1B 1IA6A 1KZPB 2KXSA 3BUDA 3BVXA 2F18A 3S9VA 3SDVA 1HM3A 1GAIA 4L9PB 4GTQB 2OOVC 2RDYA 2E22A 3HXEB 3A0OA 4D6GA 3G4DA 2D1WA 3WA2X 1LXKA 1FP3A 3P5RA 1V7WA 2WYIA 3WIQA 1RWAA 1TNOB 3NJXA 1NC5A 1NI1B 3WKIA 1NSRA 1K1WA 1KS8A 3IAQA 4DOEA 3VD9A 1LD8B 2V8IA 4FXGB 3DCDA 1CEMA 4YCRA 2WMIB 1NXCA 4WVAA 3A24A 3M71A 1LOHA 3DSTB 1TQVA 4GTTB 2CISA 1NSXA 3Q75B 4DUWA 3EJUA 3VD3A 1PX3A 1N4RB 2V8KA 1N94B 1H37A 1V5DA 3KQ4A 1TN7B 3DRAB 1H12A 3NNBA 1XWQA 2CWUA 2IEJB 3E30B 5MEHA 1AVLA 4MBGB 1W6CA 1NSMA 3DPYB 2ZQ0A 4BOKA 1RJOA 1HMWA 3HXFB 4KKJA 2NVPA 3T09A 4M76A 2QNOA 1UI7A 1TNUB 4YDEB 3M73A 2JKEA 1UG9A 2V3NA 3NFVA 1H35A 2PN5A 1HV6A 3SXXA 2Q1FA 1H36A 2CFGA 3W7UA 3KSLB 2OKXA 5DHIA 2WVXB 2P0VA 3BVTA 2OQEC 2ZL8A 3PGBA 1HX9A 3HXCB 4ONTA 3VSNA 1F4HA 2CFWA 2HTBA 1WMNA 3ON6A 3BVUA 3MUZ1 2BEDB 1HXKA 1N1BA 2WMJA 1RQ5A 3DYOA 1IQXA 4EV2A 1D8EB 1KSDA 5IKAA 1N95B 1MMUA 1F1SA 2WCOA 4LNVA 4DODA 3RX8A 1GSZA 5DGRA 3HI7A 1KREA 2A8ZA 3SDRA 1IU7A 1L7JA 4GTSB 1LTXB 2ZXQA 2FUQA 3M75A 1IVXA 1QX1A 4WVCA 1SA4B 1AV4A 1R76A 3K7XA 1HZFA 3RX5A 3UD1A 4D6EA 3E80A 1H14A 3X3YA 3M77A 4CJ0A 2XSGA 3EU8A 3K5TA 3I3EA 3DECA 1HM2A 1JZ3A 1G6IA 1HMUA 2FV1A 2JKAA 4Z4JA 2WW1A 3DSWB 1K1YA 1O1RB 4D6CA 4BTWA 4OZWA 1FAEA 5C05A 5IM1A 3Q78B 1JYWA 3PYAA 1X81B 2WINB 1K1XA 3BUQA 3D4ZA 2WO0A 1RWCA 2JKPA 1JZ8A 3EJQA 3H2WA 5CA3A 3SAEA 1FCEA 3AFLA 4GTPB 3E37B 5DHKA 2GH4A 4EL8A 3W5NA 1GXNA 2J5CA 1NSVA 1TN8B 1FT2B 1HWWA 4D1JA 1W2ZA 1F4AA 2F7QA 2CIQA 4D4DA 1NSUA 2JJBA 1N4PB 3DSSB 1QSJA 4AYQA 2EACA 4WVBA 4AYOA 1JS4A 1FO3A 3C72B 4AYPA 1R34A 3SFXB 3OXUA 1HN1A 3X41A 4DLOA 1D6ZA 1N9EA 4TF4A 1G9JA 1GXOA 2CWVA 4DLQA 3SFYB 4D6HA 1NSZA 1EGUA 3G4FA 2WIIB 4D6DA 1RWFA 3DDFA 3LZ9A 3MUY1 2BRPA 3HXBB 1KSIA 3D52A 3QDEA 1PX4A 2B39A 4BTYA 1JZ7A 1HXGA 4D1IA 2OOVA 1S63B 1UI8A 5FO9B 4K3AA 4L0GA 4ZRPA 2WMKA 2ZIRB 2DRQA 4FJQA 3QT9A 2E2VA 4DI5A 4KFFA 1VD5A 4KFDA 2ZZRA 3ANJA 1NKGA 3QXFA 3GLYA 3M00A 3PQIA 4D4CA 3CU7A 3PYBA 3VSMA 4DUXA 3T0DA 2XN1A 1L7KA 2ZISB 2BBCA 3QXQA 2WMFA 3MV01 3T0BA 3D5SA 3CIHA 3HIGA 1JCSB 2PMVA 3WVFA 3EJRA 1JZ4A 3G6JB 1HXCA 2XWJB 1IVVA 1LVNA 2F1AA 1S64B 1QBQB 1LXMA 3P2CA 2XFGA 2W0QA 1V7VA 3BUIA 2E2UA 1PU4A 2D5JA 3ECQA 3QWTA 3OEDA 2YFOA 3N0GA 3EJSA 3DSUB 2WY8A 3P5PA 1RW9A 2NOJA 1JOVA 4D94A 3UD2A 1A2VA 3BUBA 3OBAA 2WMGA 3DSXB 1DL2A 2ONHA 1SPUA 1WMOA 4RNLA 4LNBB 1QWUA 2H6GB 3QRYA 1NS4A 4GL3A 4GTRB 1DP0A 5JMDA 4E1YA 3VD5A 3MPHA 5ILHA 1N4SB 2H6FB 1N7OA 2WVYA 1XWTA 3WIWA 3T08A 1O6RA 2WOHA 4V1RA 3D4YA 3X17A 1F9GA 2Y74A 1AYXA 3ANKA 1DOGA 2CFDA 3H3KA 4D6IA 4ZH1A 3ANIA 2DRSA 1LD7B 1LURA 1SIIA 3S4BA 1CLCA 4OK4A 3T0AA 4EV5A 3M7LA 1W4NA 2F7RA 2KXRA 1NS2A 4F10A 1KKTA 3DX0A 3VW5A 5FO7B 1X1HA 1JYXA 2XQWA 3BUPA 3VXDA 2C11A 1N9AB 3SQCA 3Q1NA 1O5MB 1D6UA 4BZGA 1FBOA 4DUVA 1TNBB 4ZH5A 3Q79B 2GOXA 1N21A 5IL3A 1N7NA 1YGAA 3NBBA 1QAFA 2RI8A 4Q2BA 2OQEA 3M72A 3CZSA 4GTOB 4FNUA 2Y73A 3EJTA 3E1F1 3MI6A 3VDBA 4ZRQA 5IK0A 2ONGA 4KTRA 2YX9A 1NL4B 1IVUA 1N1ZA 1JZ5A 3Q73B 4D71A 1KFGA 3RSYA 1G87A 3X42A 1JYNA 3E32B 3KLSA 2CQSA 1MMXA 1H54A 3E7JA 1RKYA 4FNPA 3AFJA 3J7HA 2EAEA 3NJVA 5IK9A 1JRQA 2VN7A 1O1SB 3M7BA 3T0UA 5CZLA 1H3BA
chains in the Genus database with same CATH topology
2D73A 1JZ7A 3CZJA 3IMHA 3VD3A 1NSSA 1PX3A 1OJNA 4OZVA 4DUWA 3SEPA 1I8QA 4OJZA 1OJPA 3NNBA 2WVXA 2WMKA 3BS6A 3DYMA 1JZ2A 1NSMA 5JMFA 1MMYA 2ZQ0A 5A1AA 2E24A 1NKGA 3VD4A 1HMWA 1TXKA 3T09A 4BZEA 4BZFA 3VSMA 4DUXA 2BRVX 3T0DA 3I3BA 1L7KA 3IAPA 1OJMA 1Z45A 2JKEA 2WMFA 3MV01 1UG9A 2WMIA 3NFVA 2HTAA 3OS7A 3T0BA 1HV6A 3T2PA 2Q1FA 2WDAA 1JZ4A 3WVFA 1LF6A 1HN0A 2WVXB 1JYVA 1MMZA 1LXMA 3VSNA 1F4HA 4FNVA 2HTBA 2WW0A 3VD7A 2WVZA 3WFAA 1NS7A 3MUZ1 3BGAA 2WMJA 3DYOA 1RWHA 1MMUA 3ECQA 2WZSA 1F1SA 2WCOA 1LF9A 3MWXA 1C82A 1RW9A 2WW2A 1JOVA 2CIRA 3OBAA 1L7JA 4MMIA 2WMGA 4F13A 2FUQA 4D72A 2ZXQA 4J5TA 4RNLA 1N7QA 1N7PA 1NS4A 3TY1A 3VDAA 4NEIA 1DP0A 5JMDA 4E1YA 1X1IA 4D6EA 1SNZA 3OB8A 3T2OA 3VD5A 3E80A 3VDCA 1N7OA 2WVYA 3T08A 4BZHA 1MN0A 1OJOA 1F9GA 2XSGA 3T2QA 3I3EA 3DECA 1J0NA 1HM2A 4MMHA 4D6IA 1LURA 1JZ3A 1HMUA 3T0AA 1NS0A 4OK4A 2JKAA 2XHNA 1J0MA 2WW1A 1K1YA 4D6CA 1NS2A 4OZWA 4D6JA 4F10A 4D6FA 1JYWA 2WMHA 1X1HA 1YQ2A 1JYXA 1X1JA 1NS8A 1RWGA 1K1XA 3DYPA 1RWCA 2JKPA 2WW3A 1N7RA 1HM3A 3Q1NA 1JZ8A 3AFLA 4OK2A 2E22A 3A0OA 4BZGA 4DUVA 4D6GA 1YGAA 1N7NA 1NSVA 1LXKA 1F4AA 5E1QA 2CIQA 1CB8A 3E1F1 1NSUA 3VDBA 1QAZA 1RWAA 2BRWA 2FUTA 3K25A 3NJXA 4TTGA 1NSRA 1K1WA 1HN1A 1SO0A 3IAQA 3VD9A 3DCDA 1JZ5A 4D71A 3I3DA 1JYNA 2WMIB 4D6HA 1NSZA 1MMXA 3A24A 1EGUA 3E7JA 3NREA 1PX4A 4D6DA 1W3YA 1RWFA 3BLCA 3J7HA 1LOHA 2X03A 2BRPA 3NJVA 3MUY1 3MV11 1ULVA 1JZ6A 2CISA 1NSXA 4AQ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D73 A;  1JZ7 A;  3CZJ A;  3IMH A;  3VD3 A;  1NSS A;  1PX3 A;  1OJN A;  4OZV A;  4DUW A;  3SEP A;  1I8Q A;  4OJZ A;  1OJP A;  3NNB A;  2WVX A;  2WMK A;  3DYM A;  1JZ2 A;  1NSM A;  5JMF A;  1MMY A;  2ZQ0 A;  5A1A A;  2E24 A;  1NKG A;  3VD4 A;  1HMW A;  1TXK A;  3T09 A;  4BZE A;  4BZF A;  3VSM A;  4DUX A;  2BRV X;  3T0D A;  3I3B A;  1L7K A;  3IAP A;  1OJM A;  1Z45 A;  2JKE A;  2WMF A;  3MV0 1;  1UG9 A;  2WMI A;  3NFV A;  2HTA A;  3OS7 A;  3T0B A;  1HV6 A;  3T2P A;  2Q1F A;  2WDA A;  1JZ4 A;  1LF6 A;  1HN0 A;  2WVX B;  1JYV A;  1MMZ A;  1LXM A;  3VSN A;  1F4H A;  4FNV A;  2HTB A;  2WW0 A;  3VD7 A;  2WVZ A;  3WFA A;  1NS7 A;  3MUZ 1;  3BGA A;  2WMJ A;  3DYO A;  1RWH A;  1MMU A;  3ECQ A;  2WZS A;  1F1S A;  2WCO A;  1LF9 A;  3MWX A;  1C82 A;  1RW9 A;  2WW2 A;  1JOV A;  2CIR A;  3OBA A;  1L7J A;  4MMI A;  2WMG A;  4F13 A;  2FUQ A;  4D72 A;  2ZXQ A;  4RNL A;  1N7Q A;  1N7P A;  1NS4 A;  3VDA A;  4NEI A;  1DP0 A;  5JMD A;  4E1Y A;  1X1I A;  4D6E A;  1SNZ A;  3OB8 A;  3T2O A;  3VD5 A;  3E80 A;  3VDC A;  1N7O A;  2WVY A;  3T08 A;  4BZH A;  1MN0 A;  1OJO A;  1F9G A;  2XSG A;  3T2Q A;  3I3E A;  3DEC A;  1J0N A;  1HM2 A;  4MMH A;  4D6I A;  1LUR A;  1JZ3 A;  1HMU A;  3T0A A;  1NS0 A;  4OK4 A;  2JKA A;  2XHN A;  1J0M A;  2WW1 A;  1K1Y A;  4D6C A;  1NS2 A;  4OZW A;  4D6J A;  4F10 A;  4D6F A;  1JYW A;  2WMH A;  1X1H A;  1YQ2 A;  1JYX A;  1X1J A;  1NS8 A;  1RWG A;  1K1X A;  3DYP A;  1RWC A;  2JKP A;  2WW3 A;  1N7R A;  1HM3 A;  3Q1N A;  1JZ8 A;  3AFL A;  4OK2 A;  2E22 A;  3A0O A;  4BZG A;  4DUV A;  4D6G A;  1YGA A;  1N7N A;  1NSV A;  1LXK A;  1F4A A;  5E1Q A;  2CIQ A;  1CB8 A;  3E1F 1;  1NSU A;  3VDB A;  1QAZ A;  1RWA A;  2BRW A;  2FUT A;  3K25 A;  3NJX A;  4TTG A;  1NSR A;  1K1W A;  1HN1 A;  1SO0 A;  3IAQ A;  3VD9 A;  3DCD A;  1JZ5 A;  4D71 A;  3I3D A;  1JYN A;  2WMI B;  4D6H A;  1NSZ A;  1MMX A;  3A24 A;  1EGU A;  3E7J A;  3NRE A;  1PX4 A;  4D6D A;  1W3Y A;  1RWF A;  3J7H A;  1LOH A;  2X03 A;  2BRP A;  3NJV A;  3MUY 1;  3MV1 1;  1ULV A;  1JZ6 A;  2CIS A;  1NSX A;  4AQ0 A; 
#chains in the Genus database with same CATH topology
 1HCU A;  3M76 A;  3CZJ A;  1NSS A;  2WGQ A;  1OJN A;  4OZV A;  1I8Q A;  4OJZ A;  5M7Y A;  5IKH A;  3BS6 A;  1IS9 A;  3Q7F B;  1N23 A;  1AVK A;  3LVT A;  4CJ1 A;  5ILJ A;  5A1A A;  2E24 A;  5ILI A;  1UT9 A;  3SDU A;  4BZE A;  3ALA A;  1L1Y A;  3E33 B;  3W7X A;  3I3B A;  2H6H B;  3E6U A;  3IAP A;  3PZ1 B;  1OJM A;  4RNQ A;  3X40 A;  4LNG B;  1DCE B;  2WMI A;  2HTA A;  3GZK A;  1DYU A;  1W7C A;  1JCR B;  4D4A A;  2AHG A;  5E2J A;  1K72 A;  3T2P A;  3E34 B;  4L6X A;  1HTY A;  3M74 A;  2CFK A;  5ILZ A;  1LF6 A;  1GAH A;  4XUV A;  2DRO A;  2E2T A;  1WU6 A;  1N4Q B;  1H3A A;  2JF4 A;  3KSQ B;  3EU5 B;  3N9H A;  2WW0 A;  1F9O A;  2EAB A;  2WVZ A;  3BVV A;  4CE7 A;  3DX4 A;  4FNQ A;  3VD7 A;  3WIR A;  3F59 A;  3WC3 A;  5EAT A;  2F0Y B;  1RWH A;  3ACS A;  3REN A;  5GY3 A;  1TQS A;  2F1B A;  1LF9 A;  1O6Q A;  1WMP A;  1WZZ A;  3EQA A;  1C82 A;  5ILD A;  3D5R A;  3EUV B;  4KTP A;  2WW2 A;  3HII A;  1XW2 A;  1O79 A;  1GA2 A;  3QR8 A;  4J5T A;  1N7Q A;  2JG0 A;  1W6J A;  4JJJ A;  1F9D A;  4NEI A;  1X1I A;  4MU9 A;  2WY7 A;  3OB8 A;  3T2O A;  1QAK A;  5JPM B;  3NBJ A;  1O7D D;  3WKH A;  1PS3 A;  2FYV A;  3DX1 A;  4C1S A;  4FUS A;  1FBW A;  1V7X A;  1OJO A;  3S4D A;  4WU0 A;  3AMO B;  4K35 A;  2CG0 A;  3KN4 A;  3QG0 A;  5AGD A;  1W5Z A;  3M7C A;  3BLB A;  3EJP A;  1QQF A;  2XHN A;  1J0M A;  3SDQ A;  1D6Y A;  4AYR A;  4UFC A;  4D6J A;  1R33 A;  5CD2 A;  2YIK A;  4D6F A;  2BT3 A;  1X1J A;  2FV0 A;  4GAX A;  1NS8 A;  1RWG A;  1TU5 A;  3KBU C;  5FO8 B;  3DYP A;  1O1T B;  2WW3 A;  1N7R A;  1GXM A;  2OW7 A;  4OK2 A;  2CFL A;  2F7O A;  2C10 A;  1IA7 A;  1H3C A;  2V8J A;  2PNC A;  2ALW A;  2B4F A;  2XN0 A;  5GW7 A;  1KZO B;  3GT5 A;  5E1Q A;  4ZG8 A;  1CB8 A;  3D51 A;  4GTM B;  1QAZ A;  2D8L A;  1MZC B;  4D8O A;  4FXK B;  2DRR A;  2BB6 A;  2AFA A;  2BRW A;  5IL8 A;  2F7P A;  1AGM A;  2FUT A;  3K25 A;  4TTG A;  1X9D A;  3X3X A;  5FOB B;  1SO0 A;  3DX3 A;  1TQW A;  5KBP A;  1W6G A;  2I07 B;  5EAS A;  1TNZ B;  3E73 A;  2XN2 A;  3I3D A;  3SDT A;  4GTV B;  4FNS A;  3NRE A;  3LOY A;  1W3Y A;  3RX7 A;  3BLC A;  1EKM A;  2X03 A;  2EAD A;  3MV1 1;  3RJ3 A;  1ULV A;  3M7E A;  4TXT A;  1JCQ B;  1FO2 A;  1JZ6 A;  3H7L A;  4AQ0 A;  3EZ8 A;  1SIH A;  4BTX A;  3M01 A;  2D73 A;  3IMH A;  1WU4 A;  3RRS A;  2WYH A;  1FMI A;  3ACT A;  3SEP A;  3QT3 A;  3WA3 A;  1H39 A;  3WUX A;  1OJP A;  3HXD B;  2WVX A;  4FNR A;  1TNY B;  3T33 A;  3PZ2 B;  5KKB A;  1OAC A;  3DYM A;  1W6K A;  1SQC A;  2GZ6 A;  2VN4 A;  3TF4 A;  5EAU A;  5JMF A;  3W5M A;  1MMY A;  1JZ2 A;  4Q88 A;  5IK6 A;  2H6I B;  3CZN A;  1IQY A;  3KII A;  1UMP A;  3QSP A;  3VD4 A;  2CWT A;  1TXK A;  4BZF A;  5JPN B;  1C3D A;  2BRV X;  3DX2 A;  1KRF A;  1N20 A;  2A73 B;  1Z45 A;  5ILY A;  3WKF A;  3OS7 A;  3U7V A;  3M02 A;  2R2L B;  1GHQ A;  1TQT A;  2WDA A;  3M78 A;  5DGQ A;  1TQU A;  1HXA A;  3W7T A;  3WKG A;  1HN0 A;  2V3P A;  5ILK A;  1JYV A;  1G9G A;  1MMZ A;  3A3V A;  3D3I A;  3PMM A;  2BB5 A;  4LIX A;  1TN6 B;  4EHM B;  2CG1 A;  3QPF A;  2Z07 A;  2AHF A;  2ZBL A;  4FNV A;  3WFA A;  1NS7 A;  3BGA A;  5GZK A;  2G02 A;  1TF4 A;  2F6D A;  2FBA A;  1V5C A;  3K11 A;  4V1S A;  2YFN A;  1FPP B;  2WZS A;  3SX1 A;  2SQC A;  4Z4L A;  1D8D B;  5M7I A;  4FNT A;  3N0F A;  3MWX A;  3DDG A;  4D4B A;  3QFY A;  2CIR A;  4MMI A;  1KWF A;  4F13 A;  1QAL A;  4D72 A;  3W7S A;  2WYN A;  3QFZ A;  1N7P A;  3TY1 A;  3VDA A;  1SNZ A;  1KSC A;  1N24 A;  3CV5 A;  3S4A A;  3VDC A;  3BVW A;  1IVW A;  3DSV B;  3KBT C;  4BZH A;  1MN0 A;  3W7W A;  2FUZ A;  1O6H A;  3T2Q A;  4YDO B;  3D50 A;  3X3Z A;  1QWN A;  1J0N A;  2CQT A;  2XWB B;  3PZ4 B;  4MMH A;  1L2A A;  1US1 A;  2OW6 A;  3PZ3 B;  1H13 A;  1NS0 A;  4QT9 A;  2G0D A;  1GLM A;  4KKI A;  1N22 A;  3Q7A B;  1WU5 A;  2WOF A;  4BOJ A;  1SA5 B;  3S4C A;  4KFE A;  2WMH A;  1YQ2 A;  3AMO A;  2RI9 A;  2RGK A;  1FT1 B;  1IA6 A;  1KZP B;  2KXS A;  3BUD A;  3BVX A;  2F18 A;  3S9V A;  3SDV A;  1HM3 A;  1GAI A;  4L9P B;  4GTQ B;  2OOV C;  2RDY A;  2E22 A;  3HXE B;  3A0O A;  4D6G A;  3G4D A;  2D1W A;  3WA2 X;  1LXK A;  1FP3 A;  3P5R A;  1V7W A;  2WYI A;  3WIQ A;  1RWA A;  1TNO B;  3NJX A;  1NC5 A;  1NI1 B;  3WKI A;  1NSR A;  1K1W A;  1KS8 A;  3IAQ A;  4DOE A;  3VD9 A;  1LD8 B;  2V8I A;  4FXG B;  3DCD A;  1CEM A;  4YCR A;  2WMI B;  1NXC A;  4WVA A;  3A24 A;  3M71 A;  1LOH A;  3DST B;  1TQV A;  4GTT B;  2CIS A;  1NSX A;  3Q75 B;  4DUW A;  3EJU A;  3VD3 A;  1PX3 A;  1N4R B;  2V8K A;  1N94 B;  1H37 A;  1V5D A;  3KQ4 A;  1TN7 B;  3DRA B;  1H12 A;  3NNB A;  1XWQ A;  2CWU A;  2IEJ B;  3E30 B;  5MEH A;  1AVL A;  4MBG B;  1W6C A;  1NSM A;  3DPY B;  2ZQ0 A;  4BOK A;  1RJO A;  1HMW A;  3HXF B;  4KKJ A;  2NVP A;  3T09 A;  4M76 A;  2QNO A;  1UI7 A;  1TNU B;  4YDE B;  3M73 A;  2JKE A;  1UG9 A;  2V3N A;  3NFV A;  1H35 A;  2PN5 A;  1HV6 A;  3SXX A;  2Q1F A;  1H36 A;  2CFG A;  3W7U A;  3KSL B;  2OKX A;  5DHI A;  2WVX B;  2P0V A;  3BVT A;  2OQE C;  2ZL8 A;  3PGB A;  1HX9 A;  3HXC B;  4ONT A;  3VSN A;  1F4H A;  2CFW A;  2HTB A;  1WMN A;  3ON6 A;  3BVU A;  3MUZ 1;  2BED B;  1HXK A;  1N1B A;  2WMJ A;  1RQ5 A;  3DYO A;  1IQX A;  4EV2 A;  1D8E B;  1KSD A;  5IKA A;  1N95 B;  1MMU A;  1F1S A;  2WCO A;  4LNV A;  4DOD A;  3RX8 A;  1GSZ A;  5DGR A;  3HI7 A;  1KRE A;  2A8Z A;  3SDR A;  1IU7 A;  1L7J A;  4GTS B;  1LTX B;  2ZXQ A;  2FUQ A;  3M75 A;  1IVX A;  1QX1 A;  4WVC A;  1SA4 B;  1AV4 A;  1R76 A;  3K7X A;  1HZF A;  3RX5 A;  3UD1 A;  4D6E A;  3E80 A;  1H14 A;  3X3Y A;  3M77 A;  4CJ0 A;  2XSG A;  3EU8 A;  3K5T A;  3I3E A;  3DEC A;  1HM2 A;  1JZ3 A;  1G6I A;  1HMU A;  2FV1 A;  2JKA A;  4Z4J A;  2WW1 A;  3DSW B;  1K1Y A;  1O1R B;  4D6C A;  4BTW A;  4OZW A;  1FAE A;  5C05 A;  5IM1 A;  3Q78 B;  1JYW A;  3PYA A;  1X81 B;  2WIN B;  1K1X A;  3BUQ A;  3D4Z A;  2WO0 A;  1RWC A;  2JKP A;  1JZ8 A;  3EJQ A;  3H2W A;  5CA3 A;  3SAE A;  1FCE A;  3AFL A;  4GTP B;  3E37 B;  5DHK A;  2GH4 A;  4EL8 A;  3W5N A;  1GXN A;  2J5C A;  1NSV A;  1TN8 B;  1FT2 B;  1HWW A;  4D1J A;  1W2Z A;  1F4A A;  2F7Q A;  2CIQ A;  4D4D A;  1NSU A;  2JJB A;  1N4P B;  3DSS B;  1QSJ A;  4AYQ A;  2EAC A;  4WVB A;  4AYO A;  1JS4 A;  1FO3 A;  3C72 B;  4AYP A;  1R34 A;  3SFX B;  3OXU A;  1HN1 A;  3X41 A;  4DLO A;  1D6Z A;  1N9E A;  4TF4 A;  1G9J A;  1GXO A;  2CWV A;  4DLQ A;  3SFY B;  4D6H A;  1NSZ A;  1EGU A;  3G4F A;  2WII B;  4D6D A;  1RWF A;  3DDF A;  3LZ9 A;  3MUY 1;  2BRP A;  3HXB B;  1KSI A;  3D52 A;  3QDE A;  1PX4 A;  2B39 A;  4BTY A;  1JZ7 A;  1HXG A;  4D1I A;  2OOV A;  1S63 B;  1UI8 A;  5FO9 B;  4K3A A;  4L0G A;  4ZRP A;  2WMK A;  2ZIR B;  2DRQ A;  4FJQ A;  3QT9 A;  2E2V A;  4DI5 A;  4KFF A;  1VD5 A;  4KFD A;  2ZZR A;  3ANJ A;  1NKG A;  3QXF A;  3GLY A;  3M00 A;  3PQI A;  4D4C A;  3CU7 A;  3PYB A;  3VSM A;  4DUX A;  3T0D A;  2XN1 A;  1L7K A;  2ZIS B;  2BBC A;  3QXQ A;  2WMF A;  3MV0 1;  3T0B A;  3D5S A;  3CIH A;  3HIG A;  1JCS B;  2PMV A;  3WVF A;  3EJR A;  1JZ4 A;  3G6J B;  1HXC A;  2XWJ B;  1IVV A;  1LVN A;  2F1A A;  1S64 B;  1QBQ B;  1LXM A;  3P2C A;  2XFG A;  2W0Q A;  1V7V A;  3BUI A;  2E2U A;  1PU4 A;  2D5J A;  3ECQ A;  3QWT A;  3OED A;  2YFO A;  3N0G A;  3EJS A;  3DSU B;  2WY8 A;  3P5P A;  1RW9 A;  2NOJ A;  1JOV A;  4D94 A;  3UD2 A;  1A2V A;  3BUB A;  3OBA A;  2WMG A;  3DSX B;  1DL2 A;  2ONH A;  1SPU A;  1WMO A;  4RNL A;  4LNB B;  1QWU A;  2H6G B;  3QRY A;  1NS4 A;  4GL3 A;  4GTR B;  1DP0 A;  5JMD A;  4E1Y A;  3VD5 A;  3MPH A;  5ILH A;  1N4S B;  2H6F B;  1N7O A;  2WVY A;  1XWT A;  3WIW A;  3T08 A;  1O6R A;  2WOH A;  4V1R A;  3D4Y A;  3X17 A;  1F9G A;  2Y74 A;  1AYX A;  3ANK A;  1DOG A;  2CFD A;  3H3K A;  4D6I A;  4ZH1 A;  3ANI A;  2DRS A;  1LD7 B;  1LUR A;  1SII A;  3S4B A;  1CLC A;  4OK4 A;  3T0A A;  4EV5 A;  3M7L A;  1W4N A;  2F7R A;  2KXR A;  1NS2 A;  4F10 A;  1KKT A;  3DX0 A;  3VW5 A;  5FO7 B;  1X1H A;  1JYX A;  2XQW A;  3BUP A;  3VXD A;  2C11 A;  1N9A B;  3SQC A;  3Q1N A;  1O5M B;  1D6U A;  4BZG A;  1FBO A;  4DUV A;  1TNB B;  4ZH5 A;  3Q79 B;  2GOX A;  1N21 A;  5IL3 A;  1N7N A;  1YGA A;  3NBB A;  1QAF A;  2RI8 A;  4Q2B A;  2OQE A;  3M72 A;  3CZS A;  4GTO B;  4FNU A;  2Y73 A;  3EJT A;  3E1F 1;  3MI6 A;  3VDB A;  4ZRQ A;  5IK0 A;  2ONG A;  4KTR A;  2YX9 A;  1NL4 B;  1IVU A;  1N1Z A;  1JZ5 A;  3Q73 B;  4D71 A;  1KFG A;  3RSY A;  1G87 A;  3X42 A;  1JYN A;  3E32 B;  3KLS A;  2CQS A;  1MMX A;  1H54 A;  3E7J A;  1RKY A;  4FNP A;  3AFJ A;  3J7H A;  2EAE A;  3NJV A;  5IK9 A;  1JRQ A;  2VN7 A;  1O1S B;  3M7B A;  3T0U A;  5CZL A;  1H3B A; 
#chains in the Genus database with same CATH homology
 2D73 A;  1JZ7 A;  3CZJ A;  3IMH A;  3VD3 A;  1NSS A;  1PX3 A;  1OJN A;  4OZV A;  4DUW A;  3SEP A;  1I8Q A;  4OJZ A;  1OJP A;  3NNB A;  2WVX A;  2WMK A;  3BS6 A;  3DYM A;  1JZ2 A;  1NSM A;  5JMF A;  1MMY A;  2ZQ0 A;  5A1A A;  2E24 A;  1NKG A;  3VD4 A;  1HMW A;  1TXK A;  3T09 A;  4BZE A;  4BZF A;  3VSM A;  4DUX A;  2BRV X;  3T0D A;  3I3B A;  1L7K A;  3IAP A;  1OJM A;  1Z45 A;  2JKE A;  2WMF A;  3MV0 1;  1UG9 A;  2WMI A;  3NFV A;  2HTA A;  3OS7 A;  3T0B A;  1HV6 A;  3T2P A;  2Q1F A;  2WDA A;  1JZ4 A;  3WVF A;  1LF6 A;  1HN0 A;  2WVX B;  1JYV A;  1MMZ A;  1LXM A;  3VSN A;  1F4H A;  4FNV A;  2HTB A;  2WW0 A;  3VD7 A;  2WVZ A;  3WFA A;  1NS7 A;  3MUZ 1;  3BGA A;  2WMJ A;  3DYO A;  1RWH A;  1MMU A;  3ECQ A;  2WZS A;  1F1S A;  2WCO A;  1LF9 A;  3MWX A;  1C82 A;  1RW9 A;  2WW2 A;  1JOV A;  2CIR A;  3OBA A;  1L7J A;  4MMI A;  2WMG A;  4F13 A;  2FUQ A;  4D72 A;  2ZXQ A;  4J5T A;  4RNL A;  1N7Q A;  1N7P A;  1NS4 A;  3TY1 A;  3VDA A;  4NEI A;  1DP0 A;  5JMD A;  4E1Y A;  1X1I A;  4D6E A;  1SNZ A;  3OB8 A;  3T2O A;  3VD5 A;  3E80 A;  3VDC A;  1N7O A;  2WVY A;  3T08 A;  4BZH A;  1MN0 A;  1OJO A;  1F9G A;  2XSG A;  3T2Q A;  3I3E A;  3DEC A;  1J0N A;  1HM2 A;  4MMH A;  4D6I A;  1LUR A;  1JZ3 A;  1HMU A;  3T0A A;  1NS0 A;  4OK4 A;  2JKA A;  2XHN A;  1J0M A;  2WW1 A;  1K1Y A;  4D6C A;  1NS2 A;  4OZW A;  4D6J A;  4F10 A;  4D6F A;  1JYW A;  2WMH A;  1X1H A;  1YQ2 A;  1JYX A;  1X1J A;  1NS8 A;  1RWG A;  1K1X A;  3DYP A;  1RWC A;  2JKP A;  2WW3 A;  1N7R A;  1HM3 A;  3Q1N A;  1JZ8 A;  3AFL A;  4OK2 A;  2E22 A;  3A0O A;  4BZG A;  4DUV A;  4D6G A;  1YGA A;  1N7N A;  1NSV A;  1LXK A;  1F4A A;  5E1Q A;  2CIQ A;  1CB8 A;  3E1F 1;  1NSU A;  3VDB A;  1QAZ A;  1RWA A;  2BRW A;  2FUT A;  3K25 A;  3NJX A;  4TTG A;  1NSR A;  1K1W A;  1HN1 A;  1SO0 A;  3IAQ A;  3VD9 A;  3DCD A;  1JZ5 A;  4D71 A;  3I3D A;  1JYN A;  2WMI B;  4D6H A;  1NSZ A;  1MMX A;  3A24 A;  1EGU A;  3E7J A;  3NRE A;  1PX4 A;  4D6D A;  1W3Y A;  1RWF A;  3BLC A;  3J7H A;  1LOH A;  2X03 A;  2BRP A;  3NJV A;  3MUY 1;  3MV1 1;  1ULV A;  1JZ6 A;  2CIS A;  1NSX A;  4AQ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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