2KXRA

Zo1 zu5 domain mc/aa mutation
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
118
structure length
118
Chain Sequence
TVVATARGIFNSNGGVLSSIETGVSIIIPQGAIPEGVEQEIYFKVCRDNSILPPLDKEKGETLLSPLVAAGPHGLKFLKPVELRLPHCDPKTWQNKCLPGDPNYLVGANCVSVLIDHF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Tight junction protein ZO-1
total genus 8
structure length 118
sequence length 118
ec nomenclature
pdb deposition date 2010-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00791 ZU5 ZU5 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.220.30 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Chondroitinase Ac; Chain A, domain 3 2kxrA01
3KBUC 3UD1A 3F59A 2KXRA 4D8OA 2KXSA 3UD2A 3KBTC
chains in the Genus database with same CATH superfamily
1J0NA 1W3YA 1LXKA 2BRWA 1LOHA 1N7PA 2Q1FA 3F59A 2WMIA 2KXSA 3UD2A 2E24A 2WMFA 1F9GA 3KBTC 1HMUA 1X1HA 1HM2A 4D6FA 2WMHA 1RW9A 1CB8A 4D6IA 1RWCA 3UD1A 4D1IA 4D1JA 4DLOA 1OJMA 1EGUA 2BRVX 2KXRA 4D8OA 4D6JA 4DLQA 1F1SA 1C82A 1X1IA 2E22A 1J0MA 1RWHA 4D6HA 3QR8A 3KBUC 1RWGA 1HMWA 1RWAA 2WDAA 4D71A 4D6EA 2WMJA 1N7NA 1I8QA 1HM3A 1N7QA 1N7OA 3PQIA 1OJOA 4D72A 1X1JA 2BRPA 2WMGA 1N7RA 1OJPA 2WMIB 4D6CA 1HN0A 1LXMA 4D6DA 2WMKA 1RWFA 2WCOA 2X03A 3U7VA 1OJNA 4D6GA
chains in the Genus database with same CATH topology
3QR8A 3KBUC 3UD1A 3F59A 2KXRA 4D8OA 4DLOA 4DLQA 2KXSA 3PQIA 3UD2A 3KBTC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KBU C;  3UD1 A;  3F59 A;  2KXR A;  4D8O A;  2KXS A;  3UD2 A;  3KBT C; 
#chains in the Genus database with same CATH topology
 1J0N A;  1W3Y A;  1LXK A;  2BRW A;  1LOH A;  1N7P A;  2Q1F A;  3F59 A;  2WMI A;  2KXS A;  3UD2 A;  2E24 A;  2WMF A;  1F9G A;  3KBT C;  1HMU A;  1X1H A;  1HM2 A;  4D6F A;  2WMH A;  1RW9 A;  1CB8 A;  4D6I A;  1RWC A;  3UD1 A;  4D1I A;  4D1J A;  4DLO A;  1OJM A;  1EGU A;  2BRV X;  2KXR A;  4D8O A;  4D6J A;  4DLQ A;  1F1S A;  1C82 A;  1X1I A;  2E22 A;  1J0M A;  1RWH A;  4D6H A;  3QR8 A;  3KBU C;  1RWG A;  1HMW A;  1RWA A;  2WDA A;  4D71 A;  4D6E A;  2WMJ A;  1N7N A;  1I8Q A;  1HM3 A;  1N7Q A;  1N7O A;  3PQI A;  1OJO A;  4D72 A;  1X1J A;  2BRP A;  2WMG A;  1N7R A;  1OJP A;  2WMI B;  4D6C A;  1HN0 A;  1LXM A;  4D6D A;  2WMK A;  1RWF A;  2WCO A;  2X03 A;  3U7V A;  1OJN A;  4D6G A; 
#chains in the Genus database with same CATH homology
 3QR8 A;  3KBU C;  3UD1 A;  3F59 A;  2KXR A;  4D8O A;  4DLO A;  4DLQ A;  2KXS A;  3PQI A;  3UD2 A;  3KBT C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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