1LXKA

Streptococcus pneumoniae hyaluronate lyase in complex with tetrasaccharide hyaluronan substrate
Total Genus 248
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
248
sequence length
719
structure length
719
Chain Sequence
b'KDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKK'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Hyaluronate Lyase
publication title Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 248
structure length 719
sequence length 719
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1lxkA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1lxkA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1lxkA01
2WZSA 2WW3A 4FNVA 1LXMA 3I3DA 3BGAA 1F4HA 1X1JA 4OK4A 2CIQA 4BZEA 1MMZA 1N7OA 2WMGA 4F10A 3CZJA 3E80A 3OS7A 2WMHA 4D6HA 3NREA 2XHNA 2JKAA 1K1XA 1F9GA 1HMWA 1NKGA 4MMHA 1JZ5A 3OB8A 1NS2A 3WFAA 2BRPA 1YQ2A 3OBAA 3VD4A 1NSXA 1J0NA 2XSGA 3VDCA 3T08A 2WW2A 1JZ7A 4F13A 2FUTA 4E1YA 3MV11 1HMUA 3VSMA 3VDAA 3T0BA 2WVYA 3NJXA 1F4AA 2WMFA 3MUY1 1HM2A 3VD3A 4BZFA 2CIRA 4D72A 1LURA 1K1WA 1RWHA 4D6IA 4BZHA 1NS8A 3MWXA 1ULVA 4NEIA 1PX4A 2WW1A 1NS4A 3A24A 4D6JA 3DYOA 1CB8A 3T2QA 1SNZA 1RWFA 2CISA 3VD9A 2WDAA 2D73A 1JZ8A 3DECA 2WMKA 2WVZA 4D6DA 1YGAA 1JZ6A 2JKPA 1EGUA 1NSRA 3NFVA 3IAPA 1JYVA 1J0MA 1HN0A 2WW0A 1JZ3A 1N7RA 3T0AA 1RWGA 3J7HA 4AQ0A 3IMHA 3DYMA 1LXKA 1JZ2A 3DCDA 3Q1NA 3NJVA 3I3BA 1OJNA 3I3EA 3VDBA 1X1HA 1MMXA 2E22A 1N7QA 2WMIB 1W3YA 1L7KA 1OJOA 2WCOA 4D6EA 3A0OA 1K1YA 3DYPA 1MMYA 2WMIA 1C82A 2E24A 1PX3A 1OJMA 2WVXB 2ZXQA 3K25A 1MN0A 1NSVA 1TXKA 1NSMA 3MUZ1 1NSZA 1RWAA 3ECQA 1F1SA 3T2PA 2WVXA 4OJZA 4OZVA 1RWCA 5JMFA 4BZGA 3E1F1 3T0DA 2X03A 1MMUA 5A1AA 4D6CA 4RNLA 4DUWA 1LF6A 2HTBA 4TTGA 3E7JA 1NS0A 4D71A 3T2OA 1HV6A 1I8QA 4OZWA 3VD5A 1NSUA 1X1IA 4DUXA 1LOHA 4D6GA 2BRVX 3SEPA 3VD7A 1JZ4A 3NNBA 1HN1A 1OJPA 4D6FA 3MV01 1SO0A 1LF9A 5JMDA 1RW9A 2BRWA 4MMIA 1N7PA 4OK2A 3T09A 1JYWA 2FUQA 4DUVA 2Q1FA 1QAZA 1L7JA 2ZQ0A 3IAQA 1HM3A 1NS7A 2HTAA 3AFLA 1Z45A 5E1QA 1UG9A 2JKEA 1NSSA 1N7NA 1JOVA 1JYNA 1JYXA 3VSNA 2WMJA 1DP0A
chains in the Genus database with same CATH superfamily
2WZSA 4L6XA 2H6IB 4FNVA 1X1JA 1SA4B 1N7OA 1IU7A 4F10A 1H13A 1FCEA 3Q78B 3M7CA 3BVXA 1TNBB 2XHNA 1H39A 2CFDA 2JKAA 3EJRA 1KRFA 3MI6A 3W7TA 1IVUA 1IA7A 1HMWA 1NKGA 3OB8A 2XFGA 4Z4JA 1O6RA 3RRSA 3HXEB 4AYQA 4FJQA 3OBAA 3SDUA 3ALAA 1QWUA 3T08A 2D5JA 2WW2A 3EJQA 1O79A 4KKIA 1W6KA 2FUTA 4J5TA 3VSMA 3WC3A 3T0UA 3VDAA 4ZH1A 3NJXA 1F4AA 2WMFA 3M72A 2NOJA 3DDFA 4LIXA 3SFYB 3GLYA 1RWHA 1LD7B 5JPMB 1D6YA 1FT1B 1NI1B 3QFZA 4EHMB 2OOVA 1TNUB 2FUZA 1HZFA 3M76A 1L2AA 3BVUA 3A24A 2OW6A 1CB8A 2OQEC 4GTQB 1W2ZA 2CISA 3E32B 3VD9A 4TXTA 1W5ZA 1QQFA 1SIIA 1WMOA 1JZ8A 3WKFA 2WVZA 1N4PB 4DI5A 1KZPB 1JZ6A 3KSLB 2XN1A 1G9JA 1HN0A 2WW0A 4DODA 3ANIA 1JZ3A 3T0AA 1RWGA 1HCUA 3BLBA 2ONGA 3U7VA 3PZ1B 1V5CA 3D5SA 2W0QA 1N1BA 3DRAB 3NJVA 5EATA 4FNPA 5FO8B 1L1YA 3M78A 1V5DA 2EADA 5EAUA 1G9GA 2I07B 3G4DA 2A73B 3PZ3B 3DX0A 1N7QA 2V8KA 3P2CA 2AFAA 5ILKA 3DSXB 4D6EA 3SXXA 3T2OA 1O1RB 2DRRA 3S4BA 1AYXA 2ZXQA 1JRQA 5ILYA 3KSQB 1TXKA 2P0VA 3ECQA 1F9OA 2WVXA 2V8JA 2CFGA 3K11A 5GZKA 3CIHA 4D6CA 4KFFA 1IVWA 4JJJA 3D50A 1DOGA 3X3ZA 1N24A 1UMPA 3BUQA 3AFJA 1KS8A 3EZ8A 3QT3A 3QRYA 1NSUA 2BRVX 2OOVC 3W7XA 1SO0A 1LF9A 2ZBLA 5JMDA 1RW9A 4MMIA 1N7PA 4D4AA 4DUVA 1H12A 3E33B 4LNBB 2GOXA 1UI7A 1UG9A 4WU0A 1NSSA 3DSTB 1W4NA 1KWFA 3VSNA 1X1IA 2H6HB 3NBBA 3QDEA 3C72B 1N94B 1TNZB 1WZZA 5DGRA 4BZEA 2CIQA 2VN7A 2FYVA 1GAHA 1O7DD 2ZISB 1LTXB 3E80A 3D3IA 2F6DA 1GXOA 1NXCA 1V7WA 3HIIA 2WMHA 3KQ4A 4D6HA 1HWWA 1SA5B 3T33A 3UD2A 2XWJB 4DOEA 2RGKA 2YFOA 1DL2A 2PMVA 1QAKA 1JZ5A 4EL8A 3HIGA 1NS2A 3WFAA 3M75A 3Q75B 3DSUB 3VD4A 1NSXA 1J0NA 3N0GA 2XSGA 3LVTA 3X17A 4E1YA 3ACTA 3PYAA 3E73A 1VD5A 4K35A 1FPPB 2Y73A 4GTSB 1H3AA 4ZG8A 4GTVB 5IKHA 1RKYA 3W5NA 3X40A 4ZH5A 1HM2A 2R2LB 5DHKA 3WKGA 5ILDA 4BZFA 2V3PA 5IK6A 4D6IA 2PNCA 2WOFA 3AMOA 1W6JA 2XN2A 2YX9A 3SAEA 4NEIA 1WMNA 1TQUA 3WKHA 4D6JA 4BTWA 5ILJA 1GA2A 2G02A 1N9EA 1SNZA 3T2QA 1HXGA 2JJBA 1X9DA 3W7UA 3S4DA 1N21A 3DECA 3D4YA 1R33A 4ZRPA 4D6DA 2CWVA 4D1IA 1EGUA 1TN7B 2WYIA 1TNOB 1FMIA 3IAPA 1NL4B 3WUXA 2OW7A 3J7HA 1DCEB 3DPYB 1KFGA 1D6UA 4KTRA 3BUBA 2BEDB 3I3EA 2FV0A 2E22A 2WMIB 1L7KA 4Z4LA 3QR8A 1FBWA 1H37A 2V3NA 2F1AA 1X81B 5KKBA 3HXFB 4V1RA 1MMYA 2CFKA 1GAIA 3ANKA 3K25A 2H6FB 1NSVA 1PS3A 1S63B 3M02A 3RX8A 1NSMA 3MUZ1 2CG0A 4D94A 1TQWA 3W7WA 4FNRA 1HXAA 1RWCA 3KN4A 1N20A 2X03A 1MMUA 1KKTA 3M00A 5A1AA 1SIHA 2HTBA 3N0FA 1R76A 4D4BA 2WO0A 4CE7A 3BVVA 3EJUA 5M7YA 4D71A 5CZLA 1RQ5A 1HV6A 4OZWA 3SDRA 1GHQA 1LOHA 5IKAA 4D4DA 3E6UA 4D6GA 1O1SB 1TQVA 3SEPA 4EV2A 4QT9A 1WMPA 1HN1A 2D1WA 1N4SB 4GTRB 2WYNA 4ONTA 2XWBB 2BRWA 5FO7B 3T09A 4WVAA 3Q73B 2Q1FA 1QAZA 1UT9A 3QG0A 2HTAA 2ZL8A 4BTYA 1H3CA 1N7NA 3EUVB 4GL3A 1JOVA 4FNUA 1FP3A 2WMJA 1DP0A 3KBUC 3H2WA 2F7QA 4MU9A 2WW3A 1QALA 3SDQA 3EJSA 1LXMA 3I3DA 1N23A 1F4HA 4OK4A 1MMZA 4MBGB 2WMGA 3Q79B 2WYHA 3G6JB 3LZ9A 3PYBA 1TQTA 3OS7A 4L9PB 3NREA 3WA3A 3M7LA 1H14A 3DSVB 3QSPA 2WINB 3RX5A 1O5MB 1FAEA 2BT3A 2CFLA 2CFWA 3CU7A 2BRPA 2EACA 1AV4A 1YQ2A 1CEMA 1TU5A 1N4QB 3W7SA 3DDGA 5MEHA 2YIKA 3H3KA 3RX7A 2F18A 3A3VA 1QX1A 1K72A 4KTPA 4F13A 3OEDA 5IK9A 1HMUA 1N4RB 2WVYA 1PU4A 3RSYA 3MUY1 3BUIA 1XW2A 3PMMA 3HI7A 3VD3A 2CIRA 1H54A 5IK0A 2RI8A 2FV1A 4D72A 1LURA 1K1WA 5M7IA 4BZHA 2B4FA 3CV5A 4D4CA 2PN5A 1UI8A 3QWTA 2WW1A 1IVXA 3DX1A 3DYOA 1TN8B 5ILIA 3X3YA 3E30B 3ON6A 4D8OA 4GTTB 5EASA 4KFEA 2ALWA 3QT9A 3WIQA 1RWFA 2CWUA 3TY1A 4Q88A 1N95B 3SQCA 3EU8A 2F7PA 1H36A 2WDAA 3KLSA 2EAEA 2RI9A 4GTMB 1GLMA 5IM1A 3WIWA 3K7XA 1YGAA 2JKPA 1NSRA 4RNQA 1S64B 3NFVA 1JYVA 1J0MA 3GT5A 1SPUA 1N7RA 4AQ0A 3EQAA 3S9VA 3SDTA 3IMHA 4WVBA 4CJ0A 3DSWB 3Q1NA 2OQEA 3D51A 2KXSA 2E2UA 1OJNA 3WIRA 4K3AA 3VW5A 3BS6A 4LNVA 3S4AA 1IVVA 1NC5A 4UFCA 1JCQB 1W3YA 4DLQA 1DYUA 1OJOA 2WCOA 3A0OA 3M7EA 1K1YA 3LOYA 3X3XA 5FOBB 5IL3A 2E24A 1LVNA 1D8EB 1OJMA 2WVXB 3CZSA 3HXDB 4KFDA 1MN0A 3ACSA 2DROA 3QXQA 4D1JA 1C3DA 2XQWA 1KSCA 3SX1A 1QBQB 1F1SA 2JG0A 3SFXB 1IQXA 3E37B 1LD8B 5JMFA 2GH4A 3M74A 4GTPB 2YFNA 3E1F1 1LF6A 4AYOA 3MPHA 4RNLA 4DUWA 3E7JA 1XWTA 3Q7AB 1GSZA 1FO2A 2ZZRA 1QAFA 1N22A 3KIIA 3D5RA 2DRSA 1KZOB 1US1A 1JZ4A 1HXKA 1WU4A 4D6FA 3MV01 1HXCA 3P5PA 1R34A 1XWQA 3NBJA 1HX9A 2FUQA 2BB5A 2ONHA 3M73A 1L7JA 2ZQ0A 3IAQA 3X42A 1Z45A 5E1QA 2GZ6A 4DLOA 3QXFA 1JYNA 4EV5A 2H6GB 2AHGA 2EABA 1G6IA 1IA6A 3BGAA 1N9AB 4BOJA 2F7OA 3M71A 3CZJA 3UD1A 3HXCB 1OACA 3DX4A 3HXBB 1F9DA 1W6GA 2IEJB 1FO3A 1K1XA 3S4CA 3P5RA 1F9GA 3EU5B 4LNGB 4GTOB 4MMHA 5IL8A 1EKMA 4YCRA 2WIIB 5ILZA 3EJTA 2F1BA 5GY3A 3M77A 4WVCA 3VDCA 1A2VA 1H35A 2Y74A 5CD2A 4L0GA 1H3BA 1JZ7A 3MV11 2CQSA 1SQCA 1KSIA 3T0BA 2BB6A 1FT2B 2BBCA 1V7XA 3G4FA 3AMOB 1JS4A 4YDEB 3PZ4B 3WVFA 2QNOA 1WU6A 1V7VA 3BUDA 3N9HA 3RJ3A 2VN4A 1NS8A 2F0YB 3MWXA 1ULVA 4KKJA 4Q2BA 2XN0A 3D52A 1QSJA 1PX4A 3X41A 1NS4A 2ZIRB 1TQSA 1JCSB 1TNYB 3WKIA 2CWTA 3M01A 2WOHA 2FBAA 3PQIA 1CLCA 3GZKA 3BVTA 3DX3A 5KBPA 2V8IA 5DHIA 2D73A 2OKXA 1WU5A 1KREA 4CJ1A 1TN6B 2WMKA 1QWNA 2F7RA 1GXNA 4BOKA 3RENA 3BUPA 3K5TA 3H7LA 3DYMA 1LXKA 2A8ZA 1RJOA 1W7CA 3DCDA 2E2VA 1JZ2A 1GXMA 3DSSB 5ILHA 1AVLA 4FUSA 1O6QA 3I3BA 2Z07A 3BVWA 1AVKA 1TF4A 3VDBA 1X1HA 2JF4A 5E2JA 1D6ZA 2WGQA 3EJPA 4FNSA 1AGMA 4BTXA 1HTYA 2DRQA 5C05A 4GAXA 3DYPA 2G0DA 1C82A 2WMIA 2CQTA 1FBOA 1PX3A 2E2TA 1N1ZA 3QPFA 3D4ZA 5JPNB 3DX2A 3E34B 5CA3A 1IQYA 3QFYA 1O1TB 4TF4A 3VXDA 1RWAA 4FXGB 1NSZA 3BLCA 3T2PA 4OJZA 4OZVA 2D8LA 2J5CA 4BZGA 2WY8A 3T0DA 4C1SA 3M7BA 5FO9B 1W6CA 4TTGA 2NVPA 3OXUA 4FXKB 4AYPA 3WA2X 4FNQA 1IS9A 4XUVA 1NS0A 4YDOB 4V1SA 2KXRA 1I8QA 3KBTC 2C11A 4AYRA 3Q7FB 4M76A 3PZ2B 3VD5A 3SDVA 4DUXA 3F59A 3VD7A 1O6HA 1JCRB 3NNBA 2CG1A 1MZCB 2AHFA 2SQCA 4FNTA 1OJPA 4ZRQA 3TF4A 2WY7A 3PGBA 4OK2A 1KSDA 5AGDA 1JYWA 5GW7A 5DGQA 1HM3A 1NS7A 1D8DB 1G87A 3AFLA 3CZNA 2JKEA 2C10A 2RDYA 2B39A 3W5MA 1JYXA 3ANJA 1MMXA
chains in the Genus database with same CATH topology
2WZSA 2WW3A 4FNVA 1LXMA 3I3DA 3BGAA 1F4HA 1X1JA 4OK4A 2CIQA 4BZEA 1MMZA 1N7OA 2WMGA 4F10A 3CZJA 3E80A 3OS7A 2WMHA 4D6HA 3NREA 2XHNA 2JKAA 1K1XA 1F9GA 1HMWA 1NKGA 4MMHA 1JZ5A 3OB8A 1NS2A 3WFAA 2BRPA 1YQ2A 3OBAA 3VD4A 1NSXA 1J0NA 2XSGA 3VDCA 3T08A 2WW2A 1JZ7A 4F13A 2FUTA 4E1YA 3MV11 1HMUA 4J5TA 3VSMA 3VDAA 3T0BA 2WVYA 3NJXA 1F4AA 2WMFA 3MUY1 1HM2A 3VD3A 4BZFA 2CIRA 4D72A 3WVFA 1LURA 1K1WA 1RWHA 4D6IA 4BZHA 1NS8A 3MWXA 1ULVA 4NEIA 1PX4A 2WW1A 1NS4A 3A24A 4D6JA 3DYOA 1CB8A 3T2QA 1SNZA 1RWFA 3TY1A 2CISA 3VD9A 2WDAA 2D73A 1JZ8A 3DECA 2WMKA 2WVZA 4D6DA 1YGAA 1JZ6A 2JKPA 1EGUA 1NSRA 3NFVA 3IAPA 1JYVA 1J0MA 1HN0A 2WW0A 1JZ3A 1N7RA 3T0AA 1RWGA 3J7HA 4AQ0A 3IMHA 3DYMA 1LXKA 1JZ2A 3DCDA 3Q1NA 3NJVA 3I3BA 1OJNA 3BS6A 3I3EA 3VDBA 1X1HA 1MMXA 2E22A 1N7QA 2WMIB 1W3YA 1L7KA 1OJOA 2WCOA 4D6EA 3A0OA 1K1YA 3DYPA 1MMYA 2WMIA 1C82A 2E24A 1PX3A 1OJMA 2WVXB 2ZXQA 3K25A 1MN0A 1NSVA 1TXKA 1NSMA 3MUZ1 1NSZA 1RWAA 3BLCA 3ECQA 1F1SA 3T2PA 2WVXA 4OJZA 4OZVA 1RWCA 5JMFA 4BZGA 3E1F1 3T0DA 2X03A 1MMUA 5A1AA 4D6CA 4RNLA 4DUWA 1LF6A 2HTBA 4TTGA 3E7JA 1NS0A 4D71A 3T2OA 1HV6A 1I8QA 4OZWA 3VD5A 1NSUA 1X1IA 4DUXA 1LOHA 4D6GA 2BRVX 3SEPA 3VD7A 1JZ4A 3NNBA 1HN1A 1OJPA 4D6FA 3MV01 1SO0A 1LF9A 5JMDA 1RW9A 2BRWA 4MMIA 1N7PA 4OK2A 3T09A 1JYWA 2FUQA 4DUVA 2Q1FA 1QAZA 1L7JA 2ZQ0A 3IAQA 1HM3A 1NS7A 2HTAA 3AFLA 1Z45A 5E1QA 1UG9A 2JKEA 1NSSA 1N7NA 1JOVA 1JYNA 1JYXA 3VSNA 2WMJA 1DP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WZS A;  2WW3 A;  4FNV A;  1LXM A;  3I3D A;  3BGA A;  1F4H A;  1X1J A;  4OK4 A;  2CIQ A;  4BZE A;  1MMZ A;  1N7O A;  2WMG A;  4F10 A;  3CZJ A;  3E80 A;  3OS7 A;  2WMH A;  4D6H A;  3NRE A;  2XHN A;  2JKA A;  1K1X A;  1F9G A;  1HMW A;  1NKG A;  4MMH A;  1JZ5 A;  3OB8 A;  1NS2 A;  3WFA A;  2BRP A;  1YQ2 A;  3OBA A;  3VD4 A;  1NSX A;  1J0N A;  2XSG A;  3VDC A;  3T08 A;  2WW2 A;  1JZ7 A;  4F13 A;  2FUT A;  4E1Y A;  3MV1 1;  1HMU A;  3VSM A;  3VDA A;  3T0B A;  2WVY A;  3NJX A;  1F4A A;  2WMF A;  3MUY 1;  1HM2 A;  3VD3 A;  4BZF A;  2CIR A;  4D72 A;  1LUR A;  1K1W A;  1RWH A;  4D6I A;  4BZH A;  1NS8 A;  3MWX A;  1ULV A;  4NEI A;  1PX4 A;  2WW1 A;  1NS4 A;  3A24 A;  4D6J A;  3DYO A;  1CB8 A;  3T2Q A;  1SNZ A;  1RWF A;  2CIS A;  3VD9 A;  2WDA A;  2D73 A;  1JZ8 A;  3DEC A;  2WMK A;  2WVZ A;  4D6D A;  1YGA A;  1JZ6 A;  2JKP A;  1EGU A;  1NSR A;  3NFV A;  3IAP A;  1JYV A;  1J0M A;  1HN0 A;  2WW0 A;  1JZ3 A;  1N7R A;  3T0A A;  1RWG A;  3J7H A;  4AQ0 A;  3IMH A;  3DYM A;  1LXK A;  1JZ2 A;  3DCD A;  3Q1N A;  3NJV A;  3I3B A;  1OJN A;  3I3E A;  3VDB A;  1X1H A;  1MMX A;  2E22 A;  1N7Q A;  2WMI B;  1W3Y A;  1L7K A;  1OJO A;  2WCO A;  4D6E A;  3A0O A;  1K1Y A;  3DYP A;  1MMY A;  2WMI A;  1C82 A;  2E24 A;  1PX3 A;  1OJM A;  2WVX B;  2ZXQ A;  3K25 A;  1MN0 A;  1NSV A;  1TXK A;  1NSM A;  3MUZ 1;  1NSZ A;  1RWA A;  3ECQ A;  1F1S A;  3T2P A;  2WVX A;  4OJZ A;  4OZV A;  1RWC A;  5JMF A;  4BZG A;  3E1F 1;  3T0D A;  2X03 A;  1MMU A;  5A1A A;  4D6C A;  4RNL A;  4DUW A;  1LF6 A;  2HTB A;  4TTG A;  3E7J A;  1NS0 A;  4D71 A;  3T2O A;  1HV6 A;  1I8Q A;  4OZW A;  3VD5 A;  1NSU A;  1X1I A;  4DUX A;  1LOH A;  4D6G A;  2BRV X;  3SEP A;  3VD7 A;  1JZ4 A;  3NNB A;  1HN1 A;  1OJP A;  4D6F A;  3MV0 1;  1SO0 A;  1LF9 A;  5JMD A;  1RW9 A;  2BRW A;  4MMI A;  1N7P A;  4OK2 A;  3T09 A;  1JYW A;  2FUQ A;  4DUV A;  2Q1F A;  1QAZ A;  1L7J A;  2ZQ0 A;  3IAQ A;  1HM3 A;  1NS7 A;  2HTA A;  3AFL A;  1Z45 A;  5E1Q A;  1UG9 A;  2JKE A;  1NSS A;  1N7N A;  1JOV A;  1JYN A;  1JYX A;  3VSN A;  2WMJ A;  1DP0 A; 
#chains in the Genus database with same CATH topology
 2WZS A;  4L6X A;  2H6I B;  4FNV A;  1X1J A;  1SA4 B;  1N7O A;  1IU7 A;  4F10 A;  1H13 A;  1FCE A;  3Q78 B;  3M7C A;  3BVX A;  1TNB B;  2XHN A;  1H39 A;  2CFD A;  2JKA A;  3EJR A;  1KRF A;  3MI6 A;  3W7T A;  1IVU A;  1IA7 A;  1HMW A;  1NKG A;  3OB8 A;  2XFG A;  4Z4J A;  1O6R A;  3RRS A;  3HXE B;  4AYQ A;  4FJQ A;  3OBA A;  3SDU A;  3ALA A;  1QWU A;  3T08 A;  2D5J A;  2WW2 A;  3EJQ A;  1O79 A;  4KKI A;  1W6K A;  2FUT A;  4J5T A;  3VSM A;  3WC3 A;  3T0U A;  3VDA A;  4ZH1 A;  3NJX A;  1F4A A;  2WMF A;  3M72 A;  2NOJ A;  3DDF A;  4LIX A;  3SFY B;  3GLY A;  1RWH A;  1LD7 B;  5JPM B;  1D6Y A;  1FT1 B;  1NI1 B;  3QFZ A;  4EHM B;  2OOV A;  1TNU B;  2FUZ A;  1HZF A;  3M76 A;  1L2A A;  3BVU A;  3A24 A;  2OW6 A;  1CB8 A;  2OQE C;  4GTQ B;  1W2Z A;  2CIS A;  3E32 B;  3VD9 A;  4TXT A;  1W5Z A;  1QQF A;  1SII A;  1WMO A;  1JZ8 A;  3WKF A;  2WVZ A;  1N4P B;  4DI5 A;  1KZP B;  1JZ6 A;  3KSL B;  2XN1 A;  1G9J A;  1HN0 A;  2WW0 A;  4DOD A;  3ANI A;  1JZ3 A;  3T0A A;  1RWG A;  1HCU A;  3BLB A;  2ONG A;  3U7V A;  3PZ1 B;  1V5C A;  3D5S A;  2W0Q A;  1N1B A;  3DRA B;  3NJV A;  5EAT A;  4FNP A;  5FO8 B;  1L1Y A;  3M78 A;  1V5D A;  2EAD A;  5EAU A;  1G9G A;  2I07 B;  3G4D A;  2A73 B;  3PZ3 B;  3DX0 A;  1N7Q A;  2V8K A;  3P2C A;  2AFA A;  5ILK A;  3DSX B;  4D6E A;  3SXX A;  3T2O A;  1O1R B;  2DRR A;  3S4B A;  1AYX A;  2ZXQ A;  1JRQ A;  5ILY A;  3KSQ B;  1TXK A;  2P0V A;  3ECQ A;  1F9O A;  2WVX A;  2V8J A;  2CFG A;  3K11 A;  5GZK A;  3CIH A;  4D6C A;  4KFF A;  1IVW A;  4JJJ A;  3D50 A;  1DOG A;  3X3Z A;  1N24 A;  1UMP A;  3BUQ A;  3AFJ A;  1KS8 A;  3EZ8 A;  3QT3 A;  3QRY A;  1NSU A;  2BRV X;  2OOV C;  3W7X A;  1SO0 A;  1LF9 A;  2ZBL A;  5JMD A;  1RW9 A;  4MMI A;  1N7P A;  4D4A A;  4DUV A;  1H12 A;  3E33 B;  4LNB B;  2GOX A;  1UI7 A;  1UG9 A;  4WU0 A;  1NSS A;  3DST B;  1W4N A;  1KWF A;  3VSN A;  1X1I A;  2H6H B;  3NBB A;  3QDE A;  3C72 B;  1N94 B;  1TNZ B;  1WZZ A;  5DGR A;  4BZE A;  2CIQ A;  2VN7 A;  2FYV A;  1GAH A;  1O7D D;  2ZIS B;  1LTX B;  3E80 A;  3D3I A;  2F6D A;  1GXO A;  1NXC A;  1V7W A;  3HII A;  2WMH A;  3KQ4 A;  4D6H A;  1HWW A;  1SA5 B;  3T33 A;  3UD2 A;  2XWJ B;  4DOE A;  2RGK A;  2YFO A;  1DL2 A;  2PMV A;  1QAK A;  1JZ5 A;  4EL8 A;  3HIG A;  1NS2 A;  3WFA A;  3M75 A;  3Q75 B;  3DSU B;  3VD4 A;  1NSX A;  1J0N A;  3N0G A;  2XSG A;  3LVT A;  3X17 A;  4E1Y A;  3ACT A;  3PYA A;  3E73 A;  1VD5 A;  4K35 A;  1FPP B;  2Y73 A;  4GTS B;  1H3A A;  4ZG8 A;  4GTV B;  5IKH A;  1RKY A;  3W5N A;  3X40 A;  4ZH5 A;  1HM2 A;  2R2L B;  5DHK A;  3WKG A;  5ILD A;  4BZF A;  2V3P A;  5IK6 A;  4D6I A;  2PNC A;  2WOF A;  3AMO A;  1W6J A;  2XN2 A;  2YX9 A;  3SAE A;  4NEI A;  1WMN A;  1TQU A;  3WKH A;  4D6J A;  4BTW A;  5ILJ A;  1GA2 A;  2G02 A;  1N9E A;  1SNZ A;  3T2Q A;  1HXG A;  2JJB A;  1X9D A;  3W7U A;  3S4D A;  1N21 A;  3DEC A;  3D4Y A;  1R33 A;  4ZRP A;  4D6D A;  2CWV A;  4D1I A;  1EGU A;  1TN7 B;  2WYI A;  1TNO B;  1FMI A;  3IAP A;  1NL4 B;  3WUX A;  2OW7 A;  3J7H A;  1DCE B;  3DPY B;  1KFG A;  1D6U A;  4KTR A;  3BUB A;  2BED B;  3I3E A;  2FV0 A;  2E22 A;  2WMI B;  1L7K A;  4Z4L A;  3QR8 A;  1FBW A;  1H37 A;  2V3N A;  2F1A A;  1X81 B;  5KKB A;  3HXF B;  4V1R A;  1MMY A;  2CFK A;  1GAI A;  3ANK A;  3K25 A;  2H6F B;  1NSV A;  1PS3 A;  1S63 B;  3M02 A;  3RX8 A;  1NSM A;  3MUZ 1;  2CG0 A;  4D94 A;  1TQW A;  3W7W A;  4FNR A;  1HXA A;  1RWC A;  3KN4 A;  1N20 A;  2X03 A;  1MMU A;  1KKT A;  3M00 A;  5A1A A;  1SIH A;  2HTB A;  3N0F A;  1R76 A;  4D4B A;  2WO0 A;  4CE7 A;  3BVV A;  3EJU A;  5M7Y A;  4D71 A;  5CZL A;  1RQ5 A;  1HV6 A;  4OZW A;  3SDR A;  1GHQ A;  1LOH A;  5IKA A;  4D4D A;  3E6U A;  4D6G A;  1O1S B;  1TQV A;  3SEP A;  4EV2 A;  4QT9 A;  1WMP A;  1HN1 A;  2D1W A;  1N4S B;  4GTR B;  2WYN A;  4ONT A;  2XWB B;  2BRW A;  5FO7 B;  3T09 A;  4WVA A;  3Q73 B;  2Q1F A;  1QAZ A;  1UT9 A;  3QG0 A;  2HTA A;  2ZL8 A;  4BTY A;  1H3C A;  1N7N A;  3EUV B;  4GL3 A;  1JOV A;  4FNU A;  1FP3 A;  2WMJ A;  1DP0 A;  3KBU C;  3H2W A;  2F7Q A;  4MU9 A;  2WW3 A;  1QAL A;  3SDQ A;  3EJS A;  1LXM A;  3I3D A;  1N23 A;  1F4H A;  4OK4 A;  1MMZ A;  4MBG B;  2WMG A;  3Q79 B;  2WYH A;  3G6J B;  3LZ9 A;  3PYB A;  1TQT A;  3OS7 A;  4L9P B;  3NRE A;  3WA3 A;  3M7L A;  1H14 A;  3DSV B;  3QSP A;  2WIN B;  3RX5 A;  1O5M B;  1FAE A;  2BT3 A;  2CFL A;  2CFW A;  3CU7 A;  2BRP A;  2EAC A;  1AV4 A;  1YQ2 A;  1CEM A;  1TU5 A;  1N4Q B;  3W7S A;  3DDG A;  5MEH A;  2YIK A;  3H3K A;  3RX7 A;  2F18 A;  3A3V A;  1QX1 A;  1K72 A;  4KTP A;  4F13 A;  3OED A;  5IK9 A;  1HMU A;  1N4R B;  2WVY A;  1PU4 A;  3RSY A;  3MUY 1;  3BUI A;  1XW2 A;  3PMM A;  3HI7 A;  3VD3 A;  2CIR A;  1H54 A;  5IK0 A;  2RI8 A;  2FV1 A;  4D72 A;  1LUR A;  1K1W A;  5M7I A;  4BZH A;  2B4F A;  3CV5 A;  4D4C A;  2PN5 A;  1UI8 A;  3QWT A;  2WW1 A;  1IVX A;  3DX1 A;  3DYO A;  1TN8 B;  5ILI A;  3X3Y A;  3E30 B;  3ON6 A;  4D8O A;  4GTT B;  5EAS A;  4KFE A;  2ALW A;  3QT9 A;  3WIQ A;  1RWF A;  2CWU A;  3TY1 A;  4Q88 A;  1N95 B;  3SQC A;  3EU8 A;  2F7P A;  1H36 A;  2WDA A;  3KLS A;  2EAE A;  2RI9 A;  4GTM B;  1GLM A;  5IM1 A;  3WIW A;  3K7X A;  1YGA A;  2JKP A;  1NSR A;  4RNQ A;  1S64 B;  3NFV A;  1JYV A;  1J0M A;  3GT5 A;  1SPU A;  1N7R A;  4AQ0 A;  3EQA A;  3S9V A;  3SDT A;  3IMH A;  4WVB A;  4CJ0 A;  3DSW B;  3Q1N A;  2OQE A;  3D51 A;  2KXS A;  2E2U A;  1OJN A;  3WIR A;  4K3A A;  3VW5 A;  3BS6 A;  4LNV A;  3S4A A;  1IVV A;  1NC5 A;  4UFC A;  1JCQ B;  1W3Y A;  4DLQ A;  1DYU A;  1OJO A;  2WCO A;  3A0O A;  3M7E A;  1K1Y A;  3LOY A;  3X3X A;  5FOB B;  5IL3 A;  2E24 A;  1LVN A;  1D8E B;  1OJM A;  2WVX B;  3CZS A;  3HXD B;  4KFD A;  1MN0 A;  3ACS A;  2DRO A;  3QXQ A;  4D1J A;  1C3D A;  2XQW A;  1KSC A;  3SX1 A;  1QBQ B;  1F1S A;  2JG0 A;  3SFX B;  1IQX A;  3E37 B;  1LD8 B;  5JMF A;  2GH4 A;  3M74 A;  4GTP B;  2YFN A;  3E1F 1;  1LF6 A;  4AYO A;  3MPH A;  4RNL A;  4DUW A;  3E7J A;  1XWT A;  3Q7A B;  1GSZ A;  1FO2 A;  2ZZR A;  1QAF A;  1N22 A;  3KII A;  3D5R A;  2DRS A;  1KZO B;  1US1 A;  1JZ4 A;  1HXK A;  1WU4 A;  4D6F A;  3MV0 1;  1HXC A;  3P5P A;  1R34 A;  1XWQ A;  3NBJ A;  1HX9 A;  2FUQ A;  2BB5 A;  2ONH A;  3M73 A;  1L7J A;  2ZQ0 A;  3IAQ A;  3X42 A;  1Z45 A;  5E1Q A;  2GZ6 A;  4DLO A;  3QXF A;  1JYN A;  4EV5 A;  2H6G B;  2AHG A;  2EAB A;  1G6I A;  1IA6 A;  3BGA A;  1N9A B;  4BOJ A;  2F7O A;  3M71 A;  3CZJ A;  3UD1 A;  3HXC B;  1OAC A;  3DX4 A;  3HXB B;  1F9D A;  1W6G A;  2IEJ B;  1FO3 A;  1K1X A;  3S4C A;  3P5R A;  1F9G A;  3EU5 B;  4LNG B;  4GTO B;  4MMH A;  5IL8 A;  1EKM A;  4YCR A;  2WII B;  5ILZ A;  3EJT A;  2F1B A;  5GY3 A;  3M77 A;  4WVC A;  3VDC A;  1A2V A;  1H35 A;  2Y74 A;  5CD2 A;  4L0G A;  1H3B A;  1JZ7 A;  3MV1 1;  2CQS A;  1SQC A;  1KSI A;  3T0B A;  2BB6 A;  1FT2 B;  2BBC A;  1V7X A;  3G4F A;  3AMO B;  1JS4 A;  4YDE B;  3PZ4 B;  3WVF A;  2QNO A;  1WU6 A;  1V7V A;  3BUD A;  3N9H A;  3RJ3 A;  2VN4 A;  1NS8 A;  2F0Y B;  3MWX A;  1ULV A;  4KKJ A;  4Q2B A;  2XN0 A;  3D52 A;  1QSJ A;  1PX4 A;  3X41 A;  1NS4 A;  2ZIR B;  1TQS A;  1JCS B;  1TNY B;  3WKI A;  2CWT A;  3M01 A;  2WOH A;  2FBA A;  3PQI A;  1CLC A;  3GZK A;  3BVT A;  3DX3 A;  5KBP A;  2V8I A;  5DHI A;  2D73 A;  2OKX A;  1WU5 A;  1KRE A;  4CJ1 A;  1TN6 B;  2WMK A;  1QWN A;  2F7R A;  1GXN A;  4BOK A;  3REN A;  3BUP A;  3K5T A;  3H7L A;  3DYM A;  1LXK A;  2A8Z A;  1RJO A;  1W7C A;  3DCD A;  2E2V A;  1JZ2 A;  1GXM A;  3DSS B;  5ILH A;  1AVL A;  4FUS A;  1O6Q A;  3I3B A;  2Z07 A;  3BVW A;  1AVK A;  1TF4 A;  3VDB A;  1X1H A;  2JF4 A;  5E2J A;  1D6Z A;  2WGQ A;  3EJP A;  4FNS A;  1AGM A;  4BTX A;  1HTY A;  2DRQ A;  5C05 A;  4GAX A;  3DYP A;  2G0D A;  1C82 A;  2WMI A;  2CQT A;  1FBO A;  1PX3 A;  2E2T A;  1N1Z A;  3QPF A;  3D4Z A;  5JPN B;  3DX2 A;  3E34 B;  5CA3 A;  1IQY A;  3QFY A;  1O1T B;  4TF4 A;  3VXD A;  1RWA A;  4FXG B;  1NSZ A;  3BLC A;  3T2P A;  4OJZ A;  4OZV A;  2D8L A;  2J5C A;  4BZG A;  2WY8 A;  3T0D A;  4C1S A;  3M7B A;  5FO9 B;  1W6C A;  4TTG A;  2NVP A;  3OXU A;  4FXK B;  4AYP A;  3WA2 X;  4FNQ A;  1IS9 A;  4XUV A;  1NS0 A;  4YDO B;  4V1S A;  2KXR A;  1I8Q A;  3KBT C;  2C11 A;  4AYR A;  3Q7F B;  4M76 A;  3PZ2 B;  3VD5 A;  3SDV A;  4DUX A;  3F59 A;  3VD7 A;  1O6H A;  1JCR B;  3NNB A;  2CG1 A;  1MZC B;  2AHF A;  2SQC A;  4FNT A;  1OJP A;  4ZRQ A;  3TF4 A;  2WY7 A;  3PGB A;  4OK2 A;  1KSD A;  5AGD A;  1JYW A;  5GW7 A;  5DGQ A;  1HM3 A;  1NS7 A;  1D8D B;  1G87 A;  3AFL A;  3CZN A;  2JKE A;  2C10 A;  2RDY A;  2B39 A;  3W5M A;  1JYX A;  3ANJ A;  1MMX A; 
#chains in the Genus database with same CATH homology
 2WZS A;  2WW3 A;  4FNV A;  1LXM A;  3I3D A;  3BGA A;  1F4H A;  1X1J A;  4OK4 A;  2CIQ A;  4BZE A;  1MMZ A;  1N7O A;  2WMG A;  4F10 A;  3CZJ A;  3E80 A;  3OS7 A;  2WMH A;  4D6H A;  3NRE A;  2XHN A;  2JKA A;  1K1X A;  1F9G A;  1HMW A;  1NKG A;  4MMH A;  1JZ5 A;  3OB8 A;  1NS2 A;  3WFA A;  2BRP A;  1YQ2 A;  3OBA A;  3VD4 A;  1NSX A;  1J0N A;  2XSG A;  3VDC A;  3T08 A;  2WW2 A;  1JZ7 A;  4F13 A;  2FUT A;  4E1Y A;  3MV1 1;  1HMU A;  4J5T A;  3VSM A;  3VDA A;  3T0B A;  2WVY A;  3NJX A;  1F4A A;  2WMF A;  3MUY 1;  1HM2 A;  3VD3 A;  4BZF A;  2CIR A;  4D72 A;  3WVF A;  1LUR A;  1K1W A;  1RWH A;  4D6I A;  4BZH A;  1NS8 A;  3MWX A;  1ULV A;  4NEI A;  1PX4 A;  2WW1 A;  1NS4 A;  3A24 A;  4D6J A;  3DYO A;  1CB8 A;  3T2Q A;  1SNZ A;  1RWF A;  3TY1 A;  2CIS A;  3VD9 A;  2WDA A;  2D73 A;  1JZ8 A;  3DEC A;  2WMK A;  2WVZ A;  4D6D A;  1YGA A;  1JZ6 A;  2JKP A;  1EGU A;  1NSR A;  3NFV A;  3IAP A;  1JYV A;  1J0M A;  1HN0 A;  2WW0 A;  1JZ3 A;  1N7R A;  3T0A A;  1RWG A;  3J7H A;  4AQ0 A;  3IMH A;  3DYM A;  1LXK A;  1JZ2 A;  3DCD A;  3Q1N A;  3NJV A;  3I3B A;  1OJN A;  3BS6 A;  3I3E A;  3VDB A;  1X1H A;  1MMX A;  2E22 A;  1N7Q A;  2WMI B;  1W3Y A;  1L7K A;  1OJO A;  2WCO A;  4D6E A;  3A0O A;  1K1Y A;  3DYP A;  1MMY A;  2WMI A;  1C82 A;  2E24 A;  1PX3 A;  1OJM A;  2WVX B;  2ZXQ A;  3K25 A;  1MN0 A;  1NSV A;  1TXK A;  1NSM A;  3MUZ 1;  1NSZ A;  1RWA A;  3BLC A;  3ECQ A;  1F1S A;  3T2P A;  2WVX A;  4OJZ A;  4OZV A;  1RWC A;  5JMF A;  4BZG A;  3E1F 1;  3T0D A;  2X03 A;  1MMU A;  5A1A A;  4D6C A;  4RNL A;  4DUW A;  1LF6 A;  2HTB A;  4TTG A;  3E7J A;  1NS0 A;  4D71 A;  3T2O A;  1HV6 A;  1I8Q A;  4OZW A;  3VD5 A;  1NSU A;  1X1I A;  4DUX A;  1LOH A;  4D6G A;  2BRV X;  3SEP A;  3VD7 A;  1JZ4 A;  3NNB A;  1HN1 A;  1OJP A;  4D6F A;  3MV0 1;  1SO0 A;  1LF9 A;  5JMD A;  1RW9 A;  2BRW A;  4MMI A;  1N7P A;  4OK2 A;  3T09 A;  1JYW A;  2FUQ A;  4DUV A;  2Q1F A;  1QAZ A;  1L7J A;  2ZQ0 A;  3IAQ A;  1HM3 A;  1NS7 A;  2HTA A;  3AFL A;  1Z45 A;  5E1Q A;  1UG9 A;  2JKE A;  1NSS A;  1N7N A;  1JOV A;  1JYN A;  1JYX A;  3VSN A;  2WMJ A;  1DP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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