1LXKA

Streptococcus pneumoniae hyaluronate lyase in complex with tetrasaccharide hyaluronan substrate
Total Genus 248
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
248
sequence length
719
structure length
719
Chain Sequence
KDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords Hyaluronate Lyase
publication title Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
pubmed doi rcsb
source organism Streptococcus pneumoniae
total genus 248
structure length 719
sequence length 719
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1lxkA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1lxkA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1lxkA01
1SO0A 3T2PA 3A24A 2X03A 2BRPA 2WVXA 1NSZA 3T0DA 1DP0A 1X1JA 2CIRA 3DCDA 3ECQA 3DYPA 4D6EA 1OJOA 1OJPA 3T08A 1NSXA 2ZXQA 1X1HA 1NS2A 1PX3A 4D71A 4DUVA 4BZHA 3OS7A 4FNVA 4MMHA 1N7PA 1MMXA 1W3YA 1HM2A 1YQ2A 4DUWA 4D6HA 2WVZA 1C82A 2WCOA 5A1AA 1JZ5A 3AFLA 3VD4A 1JZ3A 4AQ0A 1OJNA 3A0OA 1NSMA 2HTBA 1RWHA 5E1QA 2WZSA 2WMHA 2WMIB 4D6GA 1F4AA 1NSUA 3BGAA 1JZ4A 3DECA 4D72A 4NEIA 4OJZA 4BZEA 2WVYA 2FUTA 1JZ8A 1F1SA 1RWCA 3OBAA 3MV11 1JZ2A 3Q1NA 4D6DA 1YGAA 1HV6A 3NJXA 5JMDA 1I8QA 3E1F1 1NS7A 4OZVA 1K1YA 2WW1A 3I3BA 4RNLA 3SEPA 4E1YA 1NS4A 1RWAA 3MUZ1 1HN1A 1NSSA 1LXKA 1N7QA 3VDAA 1F9GA 2ZQ0A 1N7OA 3NREA 3NFVA 1RWFA 2E24A 4OZWA 3WFAA 1TXKA 1QAZA 2WMGA 1L7JA 3MWXA 3VD5A 2E22A 1K1WA 2WMIA 3VDCA 1NSRA 4D6IA 2BRVX 2HTAA 3K25A 1JOVA 1N7RA 1J0NA 1Z45A 3T0BA 3E7JA 3IAQA 3I3EA 1LURA 4F13A 2WMJA 1OJMA 3I3DA 4D6FA 1JYWA 1ULVA 2WW3A 4MMIA 3T2OA 3VSMA 1F4HA 1HMUA 1JYVA 3IAPA 1K1XA 1NSVA 2D73A 3NJVA 3IMHA 3E80A 2BRWA 4F10A 4D6CA 1PX4A 2XSGA 1X1IA 2CIQA 2CISA 5JMFA 4D6JA 2WW2A 3T09A 3VD7A 2WDAA 4TTGA 3T2QA 2JKPA 4DUXA 3VSNA 2FUQA 2WW0A 1JZ7A 1MN0A 4BZGA 3DYMA 2XHNA 3MV01 1J0MA 1JYNA 3VD9A 1NS8A 1HN0A 1NKGA 3T0AA 3MUY1 2WVXB 1UG9A 1RW9A 1JZ6A 1L7KA 1CB8A 3VDBA 4OK4A 2WMFA 1MMUA 1MMYA 4OK2A 1HM3A 1LXMA 3CZJA 1N7NA 3DYOA 2Q1FA 1RWGA 3OB8A 1NS0A 2JKAA 2WMKA 3NNBA 3J7HA 2JKEA 1LF9A 1LOHA 4BZFA 1JYXA 1MMZA 3VD3A 1LF6A 1SNZA 1HMWA 1EGUA
chains in the Genus database with same CATH superfamily
1HCUA 2ONGA 1FAEA 1NSZA 3T0DA 1N23A 3DCDA 3WUXA 3DSXB 1TNOB 2BEDB 4D71A 2E2TA 3EUVB 1L2AA 4GTPB 3OS7A 1N7PA 2I07B 3WIWA 1WMNA 2D1WA 3AMOB 4M76A 1HM2A 4DLOA 3PZ2B 1YQ2A 2OOVC 1QBQB 3KBUC 2WCOA 3EJRA 3QDEA 4L0GA 2XN0A 1FP3A 4ZG8A 1NSMA 3WIQA 4GAXA 2A73B 4CJ1A 4YCRA 2XFGA 3WKGA 2KXSA 1HWWA 5IK9A 2WZSA 2F7RA 4D72A 3ON6A 1FMIA 2V3NA 4MU9A 3MV11 1XWQA 4Q88A 2SQCA 1YGAA 3DX3A 1IVWA 2VN4A 1FO3A 1QALA 1FBWA 4OZVA 3SEPA 1IVXA 5ILIA 3SDRA 3MUZ1 4GTVB 4DLQA 3DSWB 3M76A 3NFVA 3BUBA 4V1RA 4AYRA 3G4DA 1KSCA 5IKHA 2WMIA 3DSUB 1NSRA 1D6YA 1GXMA 4YDOB 2GH4A 4AYQA 4Z4LA 3QFYA 1N7RA 1N9EA 3EJUA 3QSPA 1O7DD 2G02A 3W5NA 1X81B 4V1SA 2F18A 1FT1B 3ANIA 4LNVA 3RX5A 3UD2A 3I3DA 2R2LB 1JYWA 1H37A 3OXUA 4ZH1A 1TQUA 4K3AA 3GLYA 3K7XA 1R76A 3E80A 5AGDA 1SA4B 4F10A 1PX4A 1KWFA 1CLCA 1FBOA 5IK0A 2J5CA 1US1A 5FO9B 3N9HA 3VD7A 1F9DA 3S4CA 2VN7A 3WKIA 1A2VA 1IA6A 1X9DA 4GTRB 2BBCA 4ZH5A 1AVKA 2JF4A 3PYAA 2XHNA 2WOHA 1NXCA 2WOFA 3PQIA 3BUQA 3X40A 3HXEB 1FO2A 1NS8A 1NC5A 3M78A 2F1BA 4LNBB 3RX7A 4K35A 3QRYA 1MZCB 1RW9A 1GAHA 5FOBB 2WYHA 1W7CA 1JZ6A 1S64B 1CB8A 3Q7FB 3AFJA 4FNRA 1V5DA 1R34A 4XUVA 1LD8B 5DHKA 1WZZA 2F0YB 2F7OA 2CG0A 3BUDA 2YFOA 3F59A 1N4PB 1RWGA 3OB8A 3M02A 5IL8A 1NS0A 2WIIB 1LF9A 1LOHA 1MMZA 3VD3A 2RDYA 1DL2A 1EGUA 2AFAA 1KFGA 2BRPA 4GL3A 3WKFA 2WVXA 5DGRA 1DP0A 1WMOA 2CIRA 1SPUA 4D6EA 2WYNA 2C11A 2CWUA 3DYPA 1OJPA 3QR8A 1DCEB 4BZHA 4FNVA 4MMHA 1HXKA 1MMXA 4RNQA 3RENA 2OOVA 1G9GA 2AHGA 3U7VA 3NBBA 1AV4A 4DUWA 4ZRQA 4D6HA 3G6JB 5A1AA 1JZ5A 2YFNA 4GTOB 5FO7B 3PZ1B 1SA5B 3A0OA 3X42A 2HTBA 2OW7A 1V7XA 3H3KA 1RWHA 4BOKA 3HI7A 4BTYA 5ILYA 2WMHA 2WMIB 1F4AA 1PU4A 3BGAA 3W5MA 3K5TA 4OJZA 1NL4B 2WVYA 2JJBA 2B4FA 3M71A 3DX1A 4D6DA 2CFLA 1KSDA 2ZL8A 3NJXA 1GSZA 1JCRB 1TNBB 2EADA 3BVWA 1GXOA 1K1YA 3M74A 1WMPA 3WC3A 1DYUA 4FNUA 5ILDA 1TQSA 1CEMA 3TY1A 5GY3A 2CWTA 2GZ6A 2DROA 4OZWA 3WFAA 3C72B 3W7TA 2WMGA 1QX1A 1TXKA 2E22A 1HZFA 3VDCA 1W6CA 5FO8B 3K25A 3QFZA 1H54A 4TXTA 1KSIA 1Z45A 2CFWA 1K72A 4F13A 5DGQA 2D5JA 2RGKA 2RI8A 3E30B 2FV1A 2IEJB 3D5SA 2B39A 2OQEC 3EJTA 3M7CA 1F4HA 1HMUA 1GA2A 3OEDA 3IAPA 2DRRA 1HX9A 3E33B 3S4DA 4TF4A 3Q75B 1W4NA 5M7YA 3SDTA 1K1XA 1NSVA 4EV2A 3NJVA 1IQYA 1L1YA 1TQTA 3M77A 2XSGA 2V8IA 3W7SA 3LVTA 3CZSA 1N4RB 2CISA 5JMFA 4D4DA 3X3XA 1H3BA 2FUQA 3KSQB 3QT9A 2E2VA 3DX4A 2H6FB 1OACA 1N21A 3DYMA 3W7UA 1IU7A 4C1SA 1HTYA 1UI7A 1D8DB 4BTXA 1GXNA 4KFDA 1HXCA 2GOXA 1O1SB 1HN0A 4D4CA 3T0AA 3X17A 2WVXB 2CWVA 3WA3A 2CFKA 1HXAA 3KBTC 2XN2A 3SFXB 1H39A 3WA2X 5ILJA 1FT2B 1MMUA 3LZ9A 1IQXA 1MMYA 3SX1A 1LXMA 3SDUA 1O6QA 3D3IA 5KBPA 1UI8A 3DYOA 4YDEB 2PN5A 1O6RA 3ANJA 5IL3A 2CQTA 4AYOA 4D8OA 1QWUA 4LIXA 1KS8A 1TU5A 1W6KA 1IA7A 2C10A 1LTXB 3VXDA 1IVUA 2KXRA 3J7HA 1LF6A 3RX8A 3HIIA 3I3EA 1HMWA 3Q79B 2DRSA 4KTPA 1SO0A 3T2PA 2RI9A 2X03A 2F7PA 3ALAA 4WVCA 5ILZA 3PGBA 5ILHA 3MI6A 3DPYB 3M72A 1OJOA 2PMVA 5CA3A 1TNYB 3M00A 1X1HA 1PX3A 4DUVA 1KKTA 3BS6A 1DOGA 2AHFA 1WU5A 2WVZA 2Y74A 3TF4A 2WY7A 5E2JA 2Y73A 3VD4A 1JZ3A 1W6JA 1OJNA 3G4FA 3ACTA 2EACA 2FV0A 1TN7B 3E34B 1JZ4A 2ZISB 3W7XA 1NI1B 3DECA 3SDVA 3BUIA 4BTWA 3OBAA 1RWCA 3WIRA 2BT3A 3Q1NA 1JZ2A 5GW7A 4KKJA 1HV6A 4FXKB 2BB6A 1XWTA 3E1F1 1NS7A 2WW1A 3PYBA 2OKXA 3I3BA 4RNLA 4E1YA 3CIHA 1RWAA 3BVUA 1KREA 1HN1A 2XWJB 1NSSA 3VDAA 1LVNA 2Z07A 2ZQ0A 1F9OA 1G9JA 2WY8A 3QXQA 4J5TA 2H6GB 4DOEA 3EJPA 2E24A 2ZIRB 4EL8A 1QAZA 3MWXA 1L7JA 1UMPA 3VD5A 1K1WA 2V3PA 3H7LA 4GTQB 4CE7A 1KRFA 5ILKA 3NBJA 4D6IA 1JOVA 2D8LA 1J0NA 1N1BA 3T0UA 3E7JA 3IAQA 4AYPA 3E37B 4Q2BA 4D6FA 2OQEA 2YIKA 1G6IA 3T2OA 4MBGB 3M75A 1TNZB 4FXGB 4L9PB 3P2CA 3PZ4B 1N24A 2F6DA 3CZNA 4D1JA 4D4AA 3D4YA 3IMHA 2BRWA 3Q73B 4GTSB 4WU0A 1QAFA 2JG0A 3HXBB 1R33A 1AGMA 5JPMB 3N0FA 2F1AA 2OW6A 3E6UA 4WVBA 3EJSA 4FNSA 4TTGA 1N20A 3CV5A 1FCEA 1N9AB 1S63B 1V5CA 3DSTB 2FUZA 4ZRPA 3VSNA 2JKPA 2WW0A 4DUXA 1V7VA 1JZ7A 2DRQA 2XWBB 3SAEA 3A3VA 4FJQA 3X3ZA 4UFCA 1J0MA 2V8KA 2ZBLA 1JYNA 2NVPA 1TQWA 3VD9A 1O1RB 3WVFA 3DDFA 1O1TB 3KIIA 1UG9A 4ONTA 4WVAA 3DRAB 1SQCA 1H13A 2EABA 4FNTA 3KLSA 4OK4A 3EU5B 2WMFA 1QWNA 3P5RA 1N4QB 3BLBA 2NOJA 2YX9A 1HM3A 4D4BA 3EZ8A 1RKYA 3GZKA 3CZJA 1H35A 1V7WA 3BVTA 1RQ5A 1TN8B 2BB5A 1IS9A 3M73A 1VD5A 3PMMA 2JKAA 1AYXA 3NNBA 3QXFA 1QAKA 3D5RA 3QG0A 1JYXA 1SNZA 3BUPA 1KZOB 3S4AA 3QPFA 1TQVA 3A24A 5KKBA 3SFYB 1X1JA 3ECQA 3HXFB 3X3YA 3S9VA 3T08A 1NSXA 5MEHA 3UD1A 2ZXQA 1NS2A 3RSYA 2WYIA 4LNGB 3WKHA 3EJQA 1W3YA 1RJOA 1C82A 3DSVB 2ZZRA 3MPHA 3AFLA 2H6IB 5CZLA 4FNPA 3DSSB 4KFEA 4BOJA 3Q7AB 1GLMA 4AQ0A 1H3AA 1LD7B 3DX0A 3M7BA 3SQCA 2P0VA 5E1QA 5JPNB 2G0DA 4D6GA 1NSUA 4FNQA 3KSLB 4NEIA 3H2WA 5C05A 2CFDA 4BZEA 2FUTA 1JZ8A 1F1SA 2CG1A 3EU8A 3BVVA 3RJ3A 1D8EB 1N94B 1I8QA 5JMDA 4Z4JA 3EQAA 1JS4A 1SIHA 3P5PA 5EATA 4EV5A 1NS4A 3AMOA 3ACSA 1TN6B 4FUSA 1LXKA 1N7QA 1F9GA 1AVLA 4QT9A 3M01A 1N7OA 1O79A 3NREA 1W6GA 1RWFA 3D52A 1H14A 5IM1A 1N95B 3BLCA 3D50A 2H6HB 3QT3A 1H36A 2BRVX 3S4BA 2HTAA 4KKIA 1H12A 3CU7A 3T0BA 3SXXA 3E32B 2XN1A 3GT5A 1G87A 1O5MB 1LURA 2WMJA 1OJMA 1JRQA 2PNCA 4DI5A 4D1IA 2QNOA 1ULVA 2WW3A 1QSJA 4MMIA 3VSMA 5GZKA 2WO0A 4L6XA 3D4ZA 1JYVA 5IK6A 2F7QA 1JCQB 3PZ3B 3KQ4A 3M7LA 3M7EA 1GAIA 5IKAA 2D73A 5EASA 1N1ZA 4JJJA 1XW2A 1IVVA 3SDQA 4D94A 4D6CA 3X41A 1H3CA 1X1IA 2CQSA 2CIQA 2ONHA 4EHMB 2EAEA 1C3DA 4D6JA 2WW2A 3T09A 2XQWA 2WDAA 3LOYA 3DDGA 1QQFA 3HIGA 2A8ZA 2V8JA 3HXDB 1O6HA 3QWTA 3T2QA 2E2UA 3KN4A 1TNUB 1EKMA 1D6UA 1MN0A 4GTTB 4BZGA 2WINB 3ANKA 4KTRA 3MV01 1UT9A 2FYVA 2WGQA 1NKGA 1W5ZA 3MUY1 1JCSB 3K11A 3N0GA 4KFFA 1N22A 3VW5A 1L7KA 3T33A 3VDBA 3RRSA 3BVXA 1HXGA 1KZPB 4OK2A 1SIIA 1GHQA 3W7WA 3DX2A 2ALWA 1N7NA 4GTMB 3E73A 3D51A 1WU6A 4DODA 2Q1FA 3HXCB 2W0QA 1W2ZA 1N4SB 5EAUA 2WMKA 2CFGA 5DHIA 4CJ0A 2FBAA 5CD2A 1D6ZA 1FPPB 5M7IA 2JKEA 1WU4A 4BZFA 3Q78B 1TF4A 1PS3A
chains in the Genus database with same CATH topology
1SO0A 3T2PA 3A24A 2X03A 2BRPA 2WVXA 1NSZA 3T0DA 1DP0A 1X1JA 2CIRA 3DCDA 3ECQA 3DYPA 4D6EA 1OJOA 1OJPA 3T08A 1NSXA 2ZXQA 1X1HA 1NS2A 1PX3A 4D71A 4DUVA 4BZHA 3OS7A 4FNVA 4MMHA 1N7PA 1MMXA 1W3YA 3BS6A 1HM2A 1YQ2A 4DUWA 4D6HA 2WVZA 1C82A 2WCOA 5A1AA 1JZ5A 3AFLA 3VD4A 1JZ3A 4AQ0A 1OJNA 3A0OA 1NSMA 2HTBA 1RWHA 5E1QA 2WZSA 2WMHA 2WMIB 4D6GA 1F4AA 1NSUA 3BGAA 1JZ4A 3DECA 4D72A 4NEIA 4OJZA 4BZEA 2WVYA 2FUTA 1JZ8A 1F1SA 1RWCA 3OBAA 3MV11 1JZ2A 3Q1NA 4D6DA 1YGAA 1HV6A 3NJXA 5JMDA 1I8QA 3E1F1 1NS7A 4OZVA 1K1YA 2WW1A 3I3BA 4RNLA 3SEPA 4E1YA 1NS4A 1RWAA 3MUZ1 1HN1A 1NSSA 1LXKA 1N7QA 3VDAA 1F9GA 3TY1A 2ZQ0A 1N7OA 4J5TA 3NREA 3NFVA 1RWFA 2E24A 4OZWA 3WFAA 3BLCA 1TXKA 1QAZA 2WMGA 1L7JA 3MWXA 3VD5A 2E22A 1K1WA 2WMIA 3VDCA 1NSRA 4D6IA 2BRVX 2HTAA 3K25A 1JOVA 1N7RA 1J0NA 1Z45A 3T0BA 3E7JA 3IAQA 3I3EA 1LURA 4F13A 2WMJA 1OJMA 3I3DA 4D6FA 1JYWA 1ULVA 2WW3A 4MMIA 3T2OA 3VSMA 1F4HA 1HMUA 1JYVA 3IAPA 1K1XA 1NSVA 2D73A 3NJVA 3IMHA 3E80A 2BRWA 4F10A 4D6CA 1PX4A 2XSGA 1X1IA 2CIQA 2CISA 5JMFA 4D6JA 2WW2A 3T09A 3VD7A 2WDAA 4TTGA 3T2QA 2JKPA 4DUXA 3VSNA 2FUQA 2WW0A 1JZ7A 1MN0A 4BZGA 3DYMA 2XHNA 3MV01 1J0MA 1JYNA 3VD9A 3WVFA 1NS8A 1HN0A 1NKGA 3T0AA 3MUY1 2WVXB 1UG9A 1RW9A 1JZ6A 1L7KA 1CB8A 3VDBA 4OK4A 2WMFA 1MMUA 1MMYA 4OK2A 1HM3A 1LXMA 3CZJA 1N7NA 3DYOA 2Q1FA 1RWGA 3OB8A 1NS0A 2JKAA 2WMKA 3NNBA 3J7HA 2JKEA 1LF9A 1LOHA 4BZFA 1JYXA 1MMZA 3VD3A 1LF6A 1SNZA 1HMWA 1EGUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SO0 A;  3T2P A;  3A24 A;  2X03 A;  2BRP A;  2WVX A;  1NSZ A;  3T0D A;  1DP0 A;  1X1J A;  2CIR A;  3DCD A;  3ECQ A;  3DYP A;  4D6E A;  1OJO A;  1OJP A;  3T08 A;  1NSX A;  2ZXQ A;  1X1H A;  1NS2 A;  1PX3 A;  4D71 A;  4DUV A;  4BZH A;  3OS7 A;  4FNV A;  4MMH A;  1N7P A;  1MMX A;  1W3Y A;  1HM2 A;  1YQ2 A;  4DUW A;  4D6H A;  2WVZ A;  1C82 A;  2WCO A;  5A1A A;  1JZ5 A;  3AFL A;  3VD4 A;  1JZ3 A;  4AQ0 A;  1OJN A;  3A0O A;  1NSM A;  2HTB A;  1RWH A;  5E1Q A;  2WZS A;  2WMH A;  2WMI B;  4D6G A;  1F4A A;  1NSU A;  3BGA A;  1JZ4 A;  3DEC A;  4D72 A;  4NEI A;  4OJZ A;  4BZE A;  2WVY A;  2FUT A;  1JZ8 A;  1F1S A;  1RWC A;  3OBA A;  3MV1 1;  1JZ2 A;  3Q1N A;  4D6D A;  1YGA A;  1HV6 A;  3NJX A;  5JMD A;  1I8Q A;  3E1F 1;  1NS7 A;  4OZV A;  1K1Y A;  2WW1 A;  3I3B A;  4RNL A;  3SEP A;  4E1Y A;  1NS4 A;  1RWA A;  3MUZ 1;  1HN1 A;  1NSS A;  1LXK A;  1N7Q A;  3VDA A;  1F9G A;  2ZQ0 A;  1N7O A;  3NRE A;  3NFV A;  1RWF A;  2E24 A;  4OZW A;  3WFA A;  1TXK A;  1QAZ A;  2WMG A;  1L7J A;  3MWX A;  3VD5 A;  2E22 A;  1K1W A;  2WMI A;  3VDC A;  1NSR A;  4D6I A;  2BRV X;  2HTA A;  3K25 A;  1JOV A;  1N7R A;  1J0N A;  1Z45 A;  3T0B A;  3E7J A;  3IAQ A;  3I3E A;  1LUR A;  4F13 A;  2WMJ A;  1OJM A;  3I3D A;  4D6F A;  1JYW A;  1ULV A;  2WW3 A;  4MMI A;  3T2O A;  3VSM A;  1F4H A;  1HMU A;  1JYV A;  3IAP A;  1K1X A;  1NSV A;  2D73 A;  3NJV A;  3IMH A;  3E80 A;  2BRW A;  4F10 A;  4D6C A;  1PX4 A;  2XSG A;  1X1I A;  2CIQ A;  2CIS A;  5JMF A;  4D6J A;  2WW2 A;  3T09 A;  3VD7 A;  2WDA A;  4TTG A;  3T2Q A;  2JKP A;  4DUX A;  3VSN A;  2FUQ A;  2WW0 A;  1JZ7 A;  1MN0 A;  4BZG A;  3DYM A;  2XHN A;  3MV0 1;  1J0M A;  1JYN A;  3VD9 A;  1NS8 A;  1HN0 A;  1NKG A;  3T0A A;  3MUY 1;  2WVX B;  1UG9 A;  1RW9 A;  1JZ6 A;  1L7K A;  1CB8 A;  3VDB A;  4OK4 A;  2WMF A;  1MMU A;  1MMY A;  4OK2 A;  1HM3 A;  1LXM A;  3CZJ A;  1N7N A;  3DYO A;  2Q1F A;  1RWG A;  3OB8 A;  1NS0 A;  2JKA A;  2WMK A;  3NNB A;  3J7H A;  2JKE A;  1LF9 A;  1LOH A;  4BZF A;  1JYX A;  1MMZ A;  3VD3 A;  1LF6 A;  1SNZ A;  1HMW A;  1EGU A; 
#chains in the Genus database with same CATH topology
 1HCU A;  2ONG A;  1FAE A;  1NSZ A;  3T0D A;  1N23 A;  3DCD A;  3WUX A;  3DSX B;  1TNO B;  2BED B;  4D71 A;  2E2T A;  3EUV B;  1L2A A;  4GTP B;  3OS7 A;  1N7P A;  2I07 B;  3WIW A;  1WMN A;  2D1W A;  3AMO B;  4M76 A;  1HM2 A;  4DLO A;  3PZ2 B;  1YQ2 A;  2OOV C;  1QBQ B;  3KBU C;  2WCO A;  3EJR A;  3QDE A;  4L0G A;  2XN0 A;  1FP3 A;  4ZG8 A;  1NSM A;  3WIQ A;  4GAX A;  2A73 B;  4CJ1 A;  4YCR A;  2XFG A;  3WKG A;  2KXS A;  1HWW A;  5IK9 A;  2WZS A;  2F7R A;  4D72 A;  3ON6 A;  1FMI A;  2V3N A;  4MU9 A;  3MV1 1;  1XWQ A;  4Q88 A;  2SQC A;  1YGA A;  3DX3 A;  1IVW A;  2VN4 A;  1FO3 A;  1QAL A;  1FBW A;  4OZV A;  3SEP A;  1IVX A;  5ILI A;  3SDR A;  3MUZ 1;  4GTV B;  4DLQ A;  3DSW B;  3M76 A;  3NFV A;  3BUB A;  4V1R A;  4AYR A;  3G4D A;  1KSC A;  5IKH A;  2WMI A;  3DSU B;  1NSR A;  1D6Y A;  1GXM A;  4YDO B;  2GH4 A;  4AYQ A;  4Z4L A;  3QFY A;  1N7R A;  1N9E A;  3EJU A;  3QSP A;  1O7D D;  2G02 A;  3W5N A;  1X81 B;  4V1S A;  2F18 A;  1FT1 B;  3ANI A;  4LNV A;  3RX5 A;  3UD2 A;  3I3D A;  2R2L B;  1JYW A;  1H37 A;  3OXU A;  4ZH1 A;  1TQU A;  4K3A A;  3GLY A;  3K7X A;  1R76 A;  3E80 A;  5AGD A;  1SA4 B;  4F10 A;  1PX4 A;  1KWF A;  1CLC A;  1FBO A;  5IK0 A;  2J5C A;  1US1 A;  5FO9 B;  3N9H A;  3VD7 A;  1F9D A;  3S4C A;  2VN7 A;  3WKI A;  1A2V A;  1IA6 A;  1X9D A;  4GTR B;  2BBC A;  4ZH5 A;  1AVK A;  2JF4 A;  3PYA A;  2XHN A;  2WOH A;  1NXC A;  2WOF A;  3PQI A;  3BUQ A;  3X40 A;  3HXE B;  1FO2 A;  1NS8 A;  1NC5 A;  3M78 A;  2F1B A;  4LNB B;  3RX7 A;  4K35 A;  3QRY A;  1MZC B;  1RW9 A;  1GAH A;  5FOB B;  2WYH A;  1W7C A;  1JZ6 A;  1S64 B;  1CB8 A;  3Q7F B;  3AFJ A;  4FNR A;  1V5D A;  1R34 A;  4XUV A;  1LD8 B;  5DHK A;  1WZZ A;  2F0Y B;  2F7O A;  2CG0 A;  3BUD A;  2YFO A;  3F59 A;  1N4P B;  1RWG A;  3OB8 A;  3M02 A;  5IL8 A;  1NS0 A;  2WII B;  1LF9 A;  1LOH A;  1MMZ A;  3VD3 A;  2RDY A;  1DL2 A;  1EGU A;  2AFA A;  1KFG A;  2BRP A;  4GL3 A;  3WKF A;  2WVX A;  5DGR A;  1DP0 A;  1WMO A;  2CIR A;  1SPU A;  4D6E A;  2WYN A;  2C11 A;  2CWU A;  3DYP A;  1OJP A;  3QR8 A;  1DCE B;  4BZH A;  4FNV A;  4MMH A;  1HXK A;  1MMX A;  4RNQ A;  3REN A;  2OOV A;  1G9G A;  2AHG A;  3U7V A;  3NBB A;  1AV4 A;  4DUW A;  4ZRQ A;  4D6H A;  3G6J B;  5A1A A;  1JZ5 A;  2YFN A;  4GTO B;  5FO7 B;  3PZ1 B;  1SA5 B;  3A0O A;  3X42 A;  2HTB A;  2OW7 A;  1V7X A;  3H3K A;  1RWH A;  4BOK A;  3HI7 A;  4BTY A;  5ILY A;  2WMH A;  2WMI B;  1F4A A;  1PU4 A;  3BGA A;  3W5M A;  3K5T A;  4OJZ A;  1NL4 B;  2WVY A;  2JJB A;  2B4F A;  3M71 A;  3DX1 A;  4D6D A;  2CFL A;  1KSD A;  2ZL8 A;  3NJX A;  1GSZ A;  1JCR B;  1TNB B;  2EAD A;  3BVW A;  1GXO A;  1K1Y A;  3M74 A;  1WMP A;  3WC3 A;  1DYU A;  4FNU A;  5ILD A;  1TQS A;  1CEM A;  3TY1 A;  5GY3 A;  2CWT A;  2GZ6 A;  2DRO A;  4OZW A;  3WFA A;  3C72 B;  3W7T A;  2WMG A;  1QX1 A;  1TXK A;  2E22 A;  1HZF A;  3VDC A;  1W6C A;  5FO8 B;  3K25 A;  3QFZ A;  1H54 A;  4TXT A;  1KSI A;  1Z45 A;  2CFW A;  1K72 A;  4F13 A;  5DGQ A;  2D5J A;  2RGK A;  2RI8 A;  3E30 B;  2FV1 A;  2IEJ B;  3D5S A;  2B39 A;  2OQE C;  3EJT A;  3M7C A;  1F4H A;  1HMU A;  1GA2 A;  3OED A;  3IAP A;  2DRR A;  1HX9 A;  3E33 B;  3S4D A;  4TF4 A;  3Q75 B;  1W4N A;  5M7Y A;  3SDT A;  1K1X A;  1NSV A;  4EV2 A;  3NJV A;  1IQY A;  1L1Y A;  1TQT A;  3M77 A;  2XSG A;  2V8I A;  3W7S A;  3LVT A;  3CZS A;  1N4R B;  2CIS A;  5JMF A;  4D4D A;  3X3X A;  1H3B A;  2FUQ A;  3KSQ B;  3QT9 A;  2E2V A;  3DX4 A;  2H6F B;  1OAC A;  1N21 A;  3DYM A;  3W7U A;  1IU7 A;  4C1S A;  1HTY A;  1UI7 A;  1D8D B;  4BTX A;  1GXN A;  4KFD A;  1HXC A;  2GOX A;  1O1S B;  1HN0 A;  4D4C A;  3T0A A;  3X17 A;  2WVX B;  2CWV A;  3WA3 A;  2CFK A;  1HXA A;  3KBT C;  2XN2 A;  3SFX B;  1H39 A;  3WA2 X;  5ILJ A;  1FT2 B;  1MMU A;  3LZ9 A;  1IQX A;  1MMY A;  3SX1 A;  1LXM A;  3SDU A;  1O6Q A;  3D3I A;  5KBP A;  1UI8 A;  3DYO A;  4YDE B;  2PN5 A;  1O6R A;  3ANJ A;  5IL3 A;  2CQT A;  4AYO A;  4D8O A;  1QWU A;  4LIX A;  1KS8 A;  1TU5 A;  1W6K A;  1IA7 A;  2C10 A;  1LTX B;  3VXD A;  1IVU A;  2KXR A;  3J7H A;  1LF6 A;  3RX8 A;  3HII A;  3I3E A;  1HMW A;  3Q79 B;  2DRS A;  4KTP A;  1SO0 A;  3T2P A;  2RI9 A;  2X03 A;  2F7P A;  3ALA A;  4WVC A;  5ILZ A;  3PGB A;  5ILH A;  3MI6 A;  3DPY B;  3M72 A;  1OJO A;  2PMV A;  5CA3 A;  1TNY B;  3M00 A;  1X1H A;  1PX3 A;  4DUV A;  1KKT A;  3BS6 A;  1DOG A;  2AHF A;  1WU5 A;  2WVZ A;  2Y74 A;  3TF4 A;  2WY7 A;  5E2J A;  2Y73 A;  3VD4 A;  1JZ3 A;  1W6J A;  1OJN A;  3G4F A;  3ACT A;  2EAC A;  2FV0 A;  1TN7 B;  3E34 B;  1JZ4 A;  2ZIS B;  3W7X A;  1NI1 B;  3DEC A;  3SDV A;  3BUI A;  4BTW A;  3OBA A;  1RWC A;  3WIR A;  2BT3 A;  3Q1N A;  1JZ2 A;  5GW7 A;  4KKJ A;  1HV6 A;  4FXK B;  2BB6 A;  1XWT A;  3E1F 1;  1NS7 A;  2WW1 A;  3PYB A;  2OKX A;  3I3B A;  4RNL A;  4E1Y A;  3CIH A;  1RWA A;  3BVU A;  1KRE A;  1HN1 A;  2XWJ B;  1NSS A;  3VDA A;  1LVN A;  2Z07 A;  2ZQ0 A;  1F9O A;  1G9J A;  2WY8 A;  3QXQ A;  4J5T A;  2H6G B;  4DOE A;  3EJP A;  2E24 A;  2ZIR B;  4EL8 A;  1QAZ A;  3MWX A;  1L7J A;  1UMP A;  3VD5 A;  1K1W A;  2V3P A;  3H7L A;  4GTQ B;  4CE7 A;  1KRF A;  5ILK A;  3NBJ A;  4D6I A;  1JOV A;  2D8L A;  1J0N A;  1N1B A;  3T0U A;  3E7J A;  3IAQ A;  4AYP A;  3E37 B;  4Q2B A;  4D6F A;  2OQE A;  2YIK A;  1G6I A;  3T2O A;  4MBG B;  3M75 A;  1TNZ B;  4FXG B;  4L9P B;  3P2C A;  3PZ4 B;  1N24 A;  2F6D A;  3CZN A;  4D1J A;  4D4A A;  3D4Y A;  3IMH A;  2BRW A;  3Q73 B;  4GTS B;  4WU0 A;  1QAF A;  2JG0 A;  3HXB B;  1R33 A;  1AGM A;  5JPM B;  3N0F A;  2F1A A;  2OW6 A;  3E6U A;  4WVB A;  3EJS A;  4FNS A;  4TTG A;  1N20 A;  3CV5 A;  1FCE A;  1N9A B;  1S63 B;  1V5C A;  3DST B;  2FUZ A;  4ZRP A;  3VSN A;  2JKP A;  2WW0 A;  4DUX A;  1V7V A;  1JZ7 A;  2DRQ A;  2XWB B;  3SAE A;  3A3V A;  4FJQ A;  3X3Z A;  4UFC A;  1J0M A;  2V8K A;  2ZBL A;  1JYN A;  2NVP A;  1TQW A;  3VD9 A;  1O1R B;  3WVF A;  3DDF A;  1O1T B;  3KII A;  1UG9 A;  4ONT A;  4WVA A;  3DRA B;  1SQC A;  1H13 A;  2EAB A;  4FNT A;  3KLS A;  4OK4 A;  3EU5 B;  2WMF A;  1QWN A;  3P5R A;  1N4Q B;  3BLB A;  2NOJ A;  2YX9 A;  1HM3 A;  4D4B A;  3EZ8 A;  1RKY A;  3GZK A;  3CZJ A;  1H35 A;  1V7W A;  3BVT A;  1RQ5 A;  1TN8 B;  2BB5 A;  1IS9 A;  3M73 A;  1VD5 A;  3PMM A;  2JKA A;  1AYX A;  3NNB A;  3QXF A;  1QAK A;  3D5R A;  3QG0 A;  1JYX A;  1SNZ A;  3BUP A;  1KZO B;  3S4A A;  3QPF A;  1TQV A;  3A24 A;  5KKB A;  3SFY B;  1X1J A;  3ECQ A;  3HXF B;  3X3Y A;  3S9V A;  3T08 A;  1NSX A;  5MEH A;  3UD1 A;  2ZXQ A;  1NS2 A;  3RSY A;  2WYI A;  4LNG B;  3WKH A;  3EJQ A;  1W3Y A;  1RJO A;  1C82 A;  3DSV B;  2ZZR A;  3MPH A;  3AFL A;  2H6I B;  5CZL A;  4FNP A;  3DSS B;  4KFE A;  4BOJ A;  3Q7A B;  1GLM A;  4AQ0 A;  1H3A A;  1LD7 B;  3DX0 A;  3M7B A;  3SQC A;  2P0V A;  5E1Q A;  5JPN B;  2G0D A;  4D6G A;  1NSU A;  4FNQ A;  3KSL B;  4NEI A;  3H2W A;  5C05 A;  2CFD A;  4BZE A;  2FUT A;  1JZ8 A;  1F1S A;  2CG1 A;  3EU8 A;  3BVV A;  3RJ3 A;  1D8E B;  1N94 B;  1I8Q A;  5JMD A;  4Z4J A;  3EQA A;  1JS4 A;  1SIH A;  3P5P A;  5EAT A;  4EV5 A;  1NS4 A;  3AMO A;  3ACS A;  1TN6 B;  4FUS A;  1LXK A;  1N7Q A;  1F9G A;  1AVL A;  4QT9 A;  3M01 A;  1N7O A;  1O79 A;  3NRE A;  1W6G A;  1RWF A;  3D52 A;  1H14 A;  5IM1 A;  1N95 B;  3BLC A;  3D50 A;  2H6H B;  3QT3 A;  1H36 A;  2BRV X;  3S4B A;  2HTA A;  4KKI A;  1H12 A;  3CU7 A;  3T0B A;  3SXX A;  3E32 B;  2XN1 A;  3GT5 A;  1G87 A;  1O5M B;  1LUR A;  2WMJ A;  1OJM A;  1JRQ A;  2PNC A;  4DI5 A;  4D1I A;  2QNO A;  1ULV A;  2WW3 A;  1QSJ A;  4MMI A;  3VSM A;  5GZK A;  2WO0 A;  4L6X A;  3D4Z A;  1JYV A;  5IK6 A;  2F7Q A;  1JCQ B;  3PZ3 B;  3KQ4 A;  3M7L A;  3M7E A;  1GAI A;  5IKA A;  2D73 A;  5EAS A;  1N1Z A;  4JJJ A;  1XW2 A;  1IVV A;  3SDQ A;  4D94 A;  4D6C A;  3X41 A;  1H3C A;  1X1I A;  2CQS A;  2CIQ A;  2ONH A;  4EHM B;  2EAE A;  1C3D A;  4D6J A;  2WW2 A;  3T09 A;  2XQW A;  2WDA A;  3LOY A;  3DDG A;  1QQF A;  3HIG A;  2A8Z A;  2V8J A;  3HXD B;  1O6H A;  3QWT A;  3T2Q A;  2E2U A;  3KN4 A;  1TNU B;  1EKM A;  1D6U A;  1MN0 A;  4GTT B;  4BZG A;  2WIN B;  3ANK A;  4KTR A;  3MV0 1;  1UT9 A;  2FYV A;  2WGQ A;  1NKG A;  1W5Z A;  3MUY 1;  1JCS B;  3K11 A;  3N0G A;  4KFF A;  1N22 A;  3VW5 A;  1L7K A;  3T33 A;  3VDB A;  3RRS A;  3BVX A;  1HXG A;  1KZP B;  4OK2 A;  1SII A;  1GHQ A;  3W7W A;  3DX2 A;  2ALW A;  1N7N A;  4GTM B;  3E73 A;  3D51 A;  1WU6 A;  4DOD A;  2Q1F A;  3HXC B;  2W0Q A;  1W2Z A;  1N4S B;  5EAU A;  2WMK A;  2CFG A;  5DHI A;  4CJ0 A;  2FBA A;  5CD2 A;  1D6Z A;  1FPP B;  5M7I A;  2JKE A;  1WU4 A;  4BZF A;  3Q78 B;  1TF4 A;  1PS3 A; 
#chains in the Genus database with same CATH homology
 1SO0 A;  3T2P A;  3A24 A;  2X03 A;  2BRP A;  2WVX A;  1NSZ A;  3T0D A;  1DP0 A;  1X1J A;  2CIR A;  3DCD A;  3ECQ A;  3DYP A;  4D6E A;  1OJO A;  1OJP A;  3T08 A;  1NSX A;  2ZXQ A;  1X1H A;  1NS2 A;  1PX3 A;  4D71 A;  4DUV A;  4BZH A;  3OS7 A;  4FNV A;  4MMH A;  1N7P A;  1MMX A;  1W3Y A;  3BS6 A;  1HM2 A;  1YQ2 A;  4DUW A;  4D6H A;  2WVZ A;  1C82 A;  2WCO A;  5A1A A;  1JZ5 A;  3AFL A;  3VD4 A;  1JZ3 A;  4AQ0 A;  1OJN A;  3A0O A;  1NSM A;  2HTB A;  1RWH A;  5E1Q A;  2WZS A;  2WMH A;  2WMI B;  4D6G A;  1F4A A;  1NSU A;  3BGA A;  1JZ4 A;  3DEC A;  4D72 A;  4NEI A;  4OJZ A;  4BZE A;  2WVY A;  2FUT A;  1JZ8 A;  1F1S A;  1RWC A;  3OBA A;  3MV1 1;  1JZ2 A;  3Q1N A;  4D6D A;  1YGA A;  1HV6 A;  3NJX A;  5JMD A;  1I8Q A;  3E1F 1;  1NS7 A;  4OZV A;  1K1Y A;  2WW1 A;  3I3B A;  4RNL A;  3SEP A;  4E1Y A;  1NS4 A;  1RWA A;  3MUZ 1;  1HN1 A;  1NSS A;  1LXK A;  1N7Q A;  3VDA A;  1F9G A;  3TY1 A;  2ZQ0 A;  1N7O A;  4J5T A;  3NRE A;  3NFV A;  1RWF A;  2E24 A;  4OZW A;  3WFA A;  3BLC A;  1TXK A;  1QAZ A;  2WMG A;  1L7J A;  3MWX A;  3VD5 A;  2E22 A;  1K1W A;  2WMI A;  3VDC A;  1NSR A;  4D6I A;  2BRV X;  2HTA A;  3K25 A;  1JOV A;  1N7R A;  1J0N A;  1Z45 A;  3T0B A;  3E7J A;  3IAQ A;  3I3E A;  1LUR A;  4F13 A;  2WMJ A;  1OJM A;  3I3D A;  4D6F A;  1JYW A;  1ULV A;  2WW3 A;  4MMI A;  3T2O A;  3VSM A;  1F4H A;  1HMU A;  1JYV A;  3IAP A;  1K1X A;  1NSV A;  2D73 A;  3NJV A;  3IMH A;  3E80 A;  2BRW A;  4F10 A;  4D6C A;  1PX4 A;  2XSG A;  1X1I A;  2CIQ A;  2CIS A;  5JMF A;  4D6J A;  2WW2 A;  3T09 A;  3VD7 A;  2WDA A;  4TTG A;  3T2Q A;  2JKP A;  4DUX A;  3VSN A;  2FUQ A;  2WW0 A;  1JZ7 A;  1MN0 A;  4BZG A;  3DYM A;  2XHN A;  3MV0 1;  1J0M A;  1JYN A;  3VD9 A;  3WVF A;  1NS8 A;  1HN0 A;  1NKG A;  3T0A A;  3MUY 1;  2WVX B;  1UG9 A;  1RW9 A;  1JZ6 A;  1L7K A;  1CB8 A;  3VDB A;  4OK4 A;  2WMF A;  1MMU A;  1MMY A;  4OK2 A;  1HM3 A;  1LXM A;  3CZJ A;  1N7N A;  3DYO A;  2Q1F A;  1RWG A;  3OB8 A;  1NS0 A;  2JKA A;  2WMK A;  3NNB A;  3J7H A;  2JKE A;  1LF9 A;  1LOH A;  4BZF A;  1JYX A;  1MMZ A;  3VD3 A;  1LF6 A;  1SNZ A;  1HMW A;  1EGU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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