1LXKA

Streptococcus pneumoniae hyaluronate lyase in complex with tetrasaccharide hyaluronan substrate
Total Genus 248
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
248
sequence length
719
structure length
719
Chain Sequence
KDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Hyaluronate Lyase
publication title Mechanism of hyaluronan degradation by Streptococcus pneumoniae hyaluronate lyase. Structures of complexes with the substrate.
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 248
structure length 719
sequence length 719
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2002-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1lxkA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1lxkA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1lxkA01
1I8QA 1MMUA 1JZ4A 2WVZA 3MWXA 1JYVA 1MMZA 3VSMA 1W3YA 4FNVA 3MV01 4D6EA 3VDBA 3VD3A 1NS8A 3VD7A 2FUQA 1N7QA 1HN1A 2JKPA 2CIQA 3ECQA 3NFVA 4DUXA 2WMIB 2BRVX 4BZFA 2CIRA 1X1IA 2WMIA 2HTBA 3I3DA 1JYNA 1OJMA 2WW1A 1JOVA 3SEPA 1PX4A 1NKGA 2WVXA 3T09A 1MMYA 3T0DA 2WMJA 3T08A 3MUY1 1NSVA 3DYMA 1F1SA 4F10A 1RW9A 1NS4A 2CISA 2WZSA 1LXMA 4BZEA 1SNZA 3I3EA 4BZHA 1NS2A 2XHNA 2ZXQA 1L7KA 4OZVA 1N7RA 2X03A 2XSGA 1K1YA 1NS7A 1N7OA 3E1F1 1JZ5A 1N7PA 1Z45A 2JKAA 4NEIA 2WW0A 3IMHA 1JZ6A 3MV11 4F13A 1NSRA 4D6GA 3T2OA 3MUZ1 5E1QA 1F4HA 3NJVA 2WCOA 1JYXA 3VDCA 1NSZA 3A24A 4MMHA 5A1AA 2BRPA 1NS0A 3NJXA 1HM3A 1TXKA 2WVXB 1PX3A 3BGAA 2ZQ0A 3VD4A 1HMUA 3A0OA 2WMGA 3CZJA 2WMHA 4OK2A 1F9GA 1MN0A 1X1JA 3VSNA 3DYPA 1HV6A 4OZWA 3IAQA 4E1YA 3VDAA 3WFAA 4DUWA 2JKEA 2BRWA 1L7JA 1NSUA 1CB8A 2WMFA 3OB8A 4D6HA 1UG9A 3NNBA 1OJPA 4OJZA 1JZ7A 1LXKA 4DUVA 1RWCA 1NSSA 2WW2A 4D6FA 1NSXA 3J7HA 4D71A 3T0AA 1HN0A 1QAZA 5JMFA 3DCDA 3T2PA 3OBAA 1LF6A 4D6CA 3K25A 1JZ2A 1YQ2A 2WW3A 2WVYA 1RWHA 1ULVA 1DP0A 2WMKA 3T0BA 1JYWA 1JZ3A 1RWAA 1X1HA 2E22A 4D6DA 3DYOA 4AQ0A 3OS7A 1JZ8A 1HM2A 3E7JA 1YGAA 3I3BA 1N7NA 2D73A 1HMWA 2WDAA 1LF9A 3VD5A 3Q1NA 1J0NA 4D6IA 1RWFA 2FUTA 1EGUA 1MMXA 4D6JA 1K1WA 4BZGA 2E24A 1NSMA 1RWGA 3IAPA 1OJNA 1SO0A 3DECA 2Q1FA 5JMDA 3T2QA 3E80A 3VD9A 1J0MA 1LOHA 4RNLA 4TTGA 1OJOA 4OK4A 3NREA 1LURA 1C82A 3AFLA 4MMIA 1K1XA 2HTAA 4D72A 1F4AA
chains in the Genus database with same CATH superfamily
1I8QA 1KSCA 1X9DA 5AGDA 3X3ZA 2F7RA 2JF4A 4GTQB 1G9GA 3S9VA 2ZL8A 3UD2A 3VDBA 3DX0A 3T33A 3EJUA 3WVFA 3W7TA 3T0UA 3LOYA 1D6UA 4WVAA 1N4QB 4YDEB 3ECQA 2FUZA 2F0YB 5GW7A 3HXCB 4DUXA 2CIRA 3W5MA 1GA2A 2SQCA 2WMIA 2WW1A 3CZSA 3SFYB 1KSIA 4KFEA 3M78A 2WYIA 3KIIA 5IL8A 4QT9A 1WMOA 5GZKA 3SX1A 1R33A 1IVXA 4EL8A 4EV2A 2VN4A 3E34B 4TXTA 3I3EA 3Q7FB 3ON6A 3CIHA 1US1A 3E33B 1NS2A 1IVVA 3M75A 3KBUC 2XSGA 4K35A 1N7OA 3EU8A 1TQVA 2V8JA 4LNVA 1W6KA 3KQ4A 1HXKA 1O6RA 4D6GA 3E73A 1WU5A 2R2LB 2CFKA 2G0DA 3KSQB 2WCOA 1O5MB 2NOJA 2FV0A 3D3IA 1IQYA 3M7CA 3SDRA 1XWQA 1O6QA 2PMVA 4WU0A 2V3NA 5FOBB 1S63B 1QWNA 3VD4A 3HXDB 3RX7A 2OW7A 3A0OA 2G02A 5ILDA 3WIWA 3M7EA 1X1JA 4BOJA 4AYQA 1TU5A 3KSLB 4OZWA 3PGBA 3WFAA 1R76A 2F1AA 2JKEA 3WKGA 1WMNA 1CB8A 1DOGA 3S4DA 1FP3A 3EZ8A 1H36A 2GZ6A 4GTMB 3W7SA 1SPUA 2WYHA 4Q2BA 2ZIRB 1O1SB 1N4SB 4DODA 3AMOA 2DRSA 1H3AA 1TN6B 2IEJB 4D4CA 4D4BA 5KKBA 1HN0A 3X3XA 1N1ZA 4CJ0A 2FBAA 1QAFA 3T2PA 2ONGA 3S4AA 1V7WA 4FXGB 1LF6A 3QR8A 3OBAA 1O7DD 3BS6A 1JCSB 4XUVA 3E32B 1N24A 2XQWA 1G6IA 2FV1A 2WW3A 3K11A 3DX3A 3HIGA 1H37A 1NI1B 1WZZA 3X41A 1O1RB 1GLMA 1LTXB 3S4CA 4CJ1A 1JZ3A 1RWAA 3DRAB 1JYWA 3Q78B 4GTRB 4V1SA 3PQIA 1N23A 1HM2A 4AYRA 4ZRQA 1IS9A 1IA6A 1HTYA 2D73A 2WDAA 3N0GA 3WKFA 4L9PB 1NXCA 3KN4A 1J0NA 4D6IA 5M7YA 5C05A 1TNUB 1MMXA 4D6JA 4K3AA 2F7QA 1R34A 5CZLA 2VN7A 2E24A 3QT3A 2KXRA 3D5SA 4D4AA 3T2QA 5IKHA 5IL3A 2RGKA 1GAIA 1VD5A 3SAEA 4TTGA 3AFJA 1HZFA 2CFGA 2CWUA 3AFLA 1CLCA 4MMIA 1QALA 2HTAA 5FO8B 1MMUA 4KKJA 4FNPA 3LVTA 3EJSA 3N0FA 5FO7B 2F7OA 2F6DA 2OQEC 1JYVA 2KXSA 1A2VA 1GHQA 4D6EA 3KBTC 1NS8A 1D8EB 1HN1A 2WY8A 1W5ZA 1AV4A 4FNUA 2ZISB 4BZFA 2ZBLA 3EQAA 1W6GA 1JYNA 1H3CA 1DYUA 3GT5A 3SEPA 3BUPA 1HX9A 2QNOA 4D1IA 2XN1A 5EASA 3A3VA 1WMPA 1JCQB 3ANJA 2WMJA 3MUY1 3T08A 1WU6A 3H2WA 4F10A 2WZSA 1FT2B 1LXMA 2CQTA 1F9OA 4LNGB 1UMPA 1W4NA 4J5TA 4GAXA 4D4DA 3SDVA 1L7KA 2OQEA 1GXOA 1C3DA 1N7RA 1NS7A 4FXKB 3SDTA 3W7XA 1N7PA 3QXQA 1V5CA 4GL3A 3WKIA 1Z45A 4BTWA 4RNQA 1AVLA 1JZ6A 1FT1B 3QFYA 2YX9A 4F13A 1OACA 5ILJA 3T2OA 1F4HA 1N21A 4GTOB 3NJVA 4FNQA 3DSUB 1H3BA 1JYXA 2AHGA 4ONTA 3DDGA 3A24A 5A1AA 2BRPA 1TXKA 1V7XA 2WVXB 1PX3A 4BTXA 1HMUA 1F9GA 4OK2A 3BVTA 1SA4B 1N22A 2H6HB 2BEDB 4Z4JA 1UI8A 2XWJB 4E1YA 1JCRB 3C72B 4DUWA 1N4PB 3WUXA 3QXFA 1L7JA 1QQFA 2PNCA 3D52A 4L0GA 2ONHA 1N20A 3HXEB 3D4ZA 1HXGA 1H54A 3M02A 3OEDA 3OB8A 3BVXA 1TNBB 3NNBA 3P5PA 3RENA 1LXKA 3M76A 1RWCA 1TQWA 2F1BA 1TQUA 2WW2A 4DUVA 3RX8A 4D6FA 4D71A 2B4FA 2JG0A 5IK9A 5JPMB 5JMFA 5ILKA 1W7CA 2F18A 3DCDA 1JZ2A 4L6XA 4GTSB 1ULVA 1TNOB 1AVKA 1DP0A 1KS8A 2WMKA 5CD2A 3WIQA 2CWVA 2W0QA 1X1HA 2E22A 3F59A 4DLQA 4D6DA 3DYOA 4GTPB 3OS7A 1YGAA 4FNTA 3WA3A 3BLCA 4EHMB 1HMWA 1NL4B 3Q1NA 1RWFA 3EJRA 2OOVC 3D51A 1EGUA 3Q73B 1K72A 3OXUA 4TF4A 1DL2A 1NSMA 1OJNA 2JJBA 2H6GB 1F9DA 2H6IB 4MBGB 3PZ3B 3QPFA 1KREA 5GY3A 3VD9A 3DX1A 2J5CA 4GTVB 3ACTA 5IKAA 4ZRPA 1L2AA 1O1TB 2I07B 2YFNA 4D72A 1F4AA 2V3PA 3CV5A 3D4YA 1D6YA 3EJTA 2WVZA 3H7LA 3KLSA 4DI5A 2EAEA 2E2UA 3MWXA 1MMZA 3VSMA 3DX2A 3VW5A 3E30B 2OOVA 3VD3A 1IU7A 3ANKA 4ZH5A 3T0DA 2JKPA 2Y74A 3SDQA 3NFVA 1D6ZA 3K5TA 2WMIB 2BRVX 4KFDA 4YDOB 3DSXB 3M73A 3PZ4B 1X1IA 5DGQA 3RRSA 2HTBA 1KSDA 3HXBB 3ALAA 3QG0A 1PX4A 1UI7A 3BUQA 2WVXA 4KKIA 3SDUA 4FNRA 3M00A 4D8OA 1NSVA 3SXXA 1F1SA 4V1RA 2CISA 5IM1A 1N4RB 1SNZA 3BVUA 2OKXA 1TQTA 3M01A 3PZ1B 4WVCA 3LZ9A 2ZXQA 4OZVA 3VXDA 3E1F1 1JZ5A 3G6JB 2CFLA 1O79A 3M71A 1L1YA 2AFAA 4NEIA 2JKAA 2WO0A 2WW0A 3BVVA 3IMHA 4LNBB 3MV11 1H35A 4YCRA 1FBOA 3MUZ1 1N94B 3RSYA 3DSTB 1LD7B 1CEMA 1D8DB 2GOXA 3G4FA 2OW6A 2XWBB 4GTTB 1SIHA 3CZJA 5DGRA 4KTPA 3ACSA 1MN0A 3PZ2B 2ZZRA 1TNZB 5CA3A 2CFWA 1KZPB 1NC5A 3PMMA 2C10A 4M76A 1H14A 2AHFA 1GXMA 1S64B 1NSUA 3PYAA 2XN0A 2XFGA 3EUVB 1KZOB 3AMOB 4D6HA 4JJJA 3EU5B 2DROA 2BB6A 3E37B 3BUIA 3QRYA 1JZ7A 2EABA 1V7VA 3SFXB 1LD8B 1NSSA 3HXFB 4EV5A 3T0AA 3QFZA 1EKMA 1QAZA 4CE7A 1SIIA 3HI7A 4D6CA 5ILIA 2NVPA 1GAHA 3D50A 2WVYA 1XWTA 4FUSA 3DSWB 1KKTA 4MU9A 3Q79B 4AQ0A 1JZ8A 2ALWA 3S4BA 3WC3A 3I3BA 3UD1A 3P5RA 3ANIA 3G4DA 3HIIA 3VD5A 4ZG8A 3PYBA 2FUTA 1K1WA 1UT9A 3BUBA 4BZGA 3P2CA 1O6HA 2D1WA 3X3YA 1H39A 3U7VA 4DLOA 5DHIA 4LIXA 2WY7A 3DPYB 1LOHA 5IK0A 5ILHA 4RNLA 3K7XA 1JRQA 3MPHA 4OK4A 1FCEA 4AYOA 1LURA 1N9EA 1IVWA 1TQSA 2CFDA 5FO9B 1K1XA 3X40A 3BUDA 4Q88A 1N95B 1PS3A 1JZ4A 1DCEB 2P0VA 4D1JA 4ZH1A 4Z4LA 3SQCA 2A8ZA 5IK6A 2WYNA 2RI9A 2CG0A 1AGMA 1W3YA 1RJOA 4FNVA 3H3KA 3MV01 1GXNA 3M74A 2C11A 3VD7A 1FMIA 1N7QA 2FUQA 3Q7AB 5KBPA 2CIQA 1HWWA 1XW2A 2CQSA 3RJ3A 1N1BA 3QWTA 3I3DA 1OJMA 3CZNA 1JOVA 1HCUA 2WGQA 1H13A 1NKGA 2V8KA 3T09A 3X17A 1FO2A 1MMYA 2WOFA 1G9JA 2Y73A 1KRFA 3TF4A 1QX1A 2EADA 3DYMA 3WIRA 4AYPA 3NBJA 1RW9A 1FBWA 2DRRA 1NS4A 3N9HA 4BZEA 3DSVB 4FJQA 2EACA 4BZHA 3DX4A 3EJQA 1TF4A 3QDEA 3QT9A 2XHNA 1W6JA 2A73B 3DSSB 2X03A 2GH4A 1K1YA 3CU7A 1KFGA 3Q75B 2WIIB 4BOKA 1WU4A 2E2TA 2V8IA 1IVUA 3QSPA 1IQXA 1NSRA 1QAKA 1N9AB 5E1QA 1PU4A 3GZKA 3EJPA 3VDCA 2BT3A 1NSZA 4D94A 4MMHA 1NS0A 3NJXA 1HM3A 4KTRA 3BGAA 2ZQ0A 1IA7A 1HXCA 1TN8B 2BBCA 2WMGA 2WMHA 3VSNA 1H12A 2D8LA 3DYPA 1HV6A 4KFFA 3IAQA 3VDAA 2B39A 2BRWA 1JS4A 3BLBA 3DDFA 2H6FB 2WOHA 2CWTA 2RI8A 1W2ZA 2CG1A 1TN7B 1SA5B 2WMFA 1RQ5A 3M7BA 1TNYB 1UG9A 5EATA 1MZCB 1OJPA 4OJZA 1QSJA 1QWUA 5ILYA 2DRQA 5ILZA 1NSXA 3M72A 3J7HA 4BTYA 1W6CA 1LVNA 1HXAA 3M77A 2D5JA 2Z07A 3K25A 1GSZA 1FPPB 1FO3A 3RX5A 1YQ2A 3W7UA 2YFOA 5EAUA 2XN2A 1RWHA 1X81B 4DOEA 4UFCA 3T0BA 4FNSA 1KWFA 3WKHA 3BVWA 1V5DA 3NBBA 3W5NA 2YIKA 1SQCA 3D5RA 3E7JA 4C1SA 3TY1A 1N7NA 2FYVA 5JPNB 3MI6A 2PN5A 1LF9A 3E6UA 2E2VA 1AYXA 1FAEA 1QBQB 3GLYA 2BB5A 2RDYA 3M7LA 3X42A 3W7WA 1RWGA 5MEHA 3IAPA 1SO0A 5E2JA 1RKYA 5M7IA 3DECA 2Q1FA 5JMDA 2WINB 5DHKA 3E80A 4WVBA 1J0MA 2F7PA 1G87A 1OJOA 3NREA 1C82A 3WA2X
chains in the Genus database with same CATH topology
1I8QA 1MMUA 1JZ4A 2WVZA 3MWXA 1JYVA 1MMZA 3VSMA 1W3YA 4FNVA 3MV01 4D6EA 3VDBA 3VD3A 1NS8A 3VD7A 3WVFA 2FUQA 1N7QA 1HN1A 2JKPA 2CIQA 3ECQA 3NFVA 4DUXA 2WMIB 2BRVX 4BZFA 2CIRA 1X1IA 2WMIA 2HTBA 3I3DA 1JYNA 1OJMA 2WW1A 1JOVA 3SEPA 1PX4A 1NKGA 2WVXA 3T09A 1MMYA 3T0DA 2WMJA 3T08A 3MUY1 1NSVA 3DYMA 1F1SA 4F10A 1RW9A 1NS4A 2CISA 2WZSA 1LXMA 4BZEA 1SNZA 3I3EA 4BZHA 4J5TA 1NS2A 2XHNA 2ZXQA 1L7KA 4OZVA 1N7RA 2X03A 2XSGA 1K1YA 1NS7A 1N7OA 3E1F1 1JZ5A 1N7PA 1Z45A 2JKAA 4NEIA 2WW0A 3IMHA 1JZ6A 3MV11 4F13A 1NSRA 4D6GA 3T2OA 3MUZ1 5E1QA 1F4HA 3NJVA 2WCOA 1JYXA 3VDCA 1NSZA 3A24A 4MMHA 5A1AA 2BRPA 1NS0A 3NJXA 1HM3A 1TXKA 2WVXB 1PX3A 3BGAA 2ZQ0A 3VD4A 1HMUA 3A0OA 2WMGA 3CZJA 2WMHA 4OK2A 1F9GA 1MN0A 1X1JA 3VSNA 3DYPA 1HV6A 4OZWA 3IAQA 4E1YA 3VDAA 3WFAA 4DUWA 2JKEA 2BRWA 1L7JA 1NSUA 1CB8A 2WMFA 3OB8A 4D6HA 1UG9A 3NNBA 1OJPA 4OJZA 1JZ7A 1LXKA 4DUVA 1RWCA 1NSSA 2WW2A 4D6FA 1NSXA 3J7HA 4D71A 3T0AA 1HN0A 1QAZA 5JMFA 3DCDA 3T2PA 3OBAA 1LF6A 4D6CA 3BS6A 3K25A 1JZ2A 1YQ2A 2WW3A 2WVYA 1RWHA 1ULVA 1DP0A 2WMKA 3T0BA 1JYWA 1JZ3A 1RWAA 1X1HA 2E22A 4D6DA 3DYOA 4AQ0A 3OS7A 1JZ8A 3TY1A 1HM2A 3E7JA 1YGAA 3I3BA 1N7NA 3BLCA 2D73A 1HMWA 2WDAA 1LF9A 3VD5A 3Q1NA 1J0NA 4D6IA 1RWFA 2FUTA 1EGUA 1MMXA 4D6JA 1K1WA 4BZGA 2E24A 1NSMA 1RWGA 3IAPA 1OJNA 1SO0A 3DECA 2Q1FA 5JMDA 3T2QA 3E80A 3VD9A 1J0MA 1LOHA 4RNLA 4TTGA 1OJOA 4OK4A 3NREA 1LURA 1C82A 3AFLA 4MMIA 1K1XA 2HTAA 4D72A 1F4AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I8Q A;  1MMU A;  1JZ4 A;  2WVZ A;  3MWX A;  1JYV A;  1MMZ A;  3VSM A;  1W3Y A;  4FNV A;  3MV0 1;  4D6E A;  3VDB A;  3VD3 A;  1NS8 A;  3VD7 A;  2FUQ A;  1N7Q A;  1HN1 A;  2JKP A;  2CIQ A;  3ECQ A;  3NFV A;  4DUX A;  2WMI B;  2BRV X;  4BZF A;  2CIR A;  1X1I A;  2WMI A;  2HTB A;  3I3D A;  1JYN A;  1OJM A;  2WW1 A;  1JOV A;  3SEP A;  1PX4 A;  1NKG A;  2WVX A;  3T09 A;  1MMY A;  3T0D A;  2WMJ A;  3T08 A;  3MUY 1;  1NSV A;  3DYM A;  1F1S A;  4F10 A;  1RW9 A;  1NS4 A;  2CIS A;  2WZS A;  1LXM A;  4BZE A;  1SNZ A;  3I3E A;  4BZH A;  1NS2 A;  2XHN A;  2ZXQ A;  1L7K A;  4OZV A;  1N7R A;  2X03 A;  2XSG A;  1K1Y A;  1NS7 A;  1N7O A;  3E1F 1;  1JZ5 A;  1N7P A;  1Z45 A;  2JKA A;  4NEI A;  2WW0 A;  3IMH A;  1JZ6 A;  3MV1 1;  4F13 A;  1NSR A;  4D6G A;  3T2O A;  3MUZ 1;  5E1Q A;  1F4H A;  3NJV A;  2WCO A;  1JYX A;  3VDC A;  1NSZ A;  3A24 A;  4MMH A;  5A1A A;  2BRP A;  1NS0 A;  3NJX A;  1HM3 A;  1TXK A;  2WVX B;  1PX3 A;  3BGA A;  2ZQ0 A;  3VD4 A;  1HMU A;  3A0O A;  2WMG A;  3CZJ A;  2WMH A;  4OK2 A;  1F9G A;  1MN0 A;  1X1J A;  3VSN A;  3DYP A;  1HV6 A;  4OZW A;  3IAQ A;  4E1Y A;  3VDA A;  3WFA A;  4DUW A;  2JKE A;  2BRW A;  1L7J A;  1NSU A;  1CB8 A;  2WMF A;  3OB8 A;  4D6H A;  1UG9 A;  3NNB A;  1OJP A;  4OJZ A;  1JZ7 A;  1LXK A;  4DUV A;  1RWC A;  1NSS A;  2WW2 A;  4D6F A;  1NSX A;  3J7H A;  4D71 A;  3T0A A;  1HN0 A;  1QAZ A;  5JMF A;  3DCD A;  3T2P A;  3OBA A;  1LF6 A;  4D6C A;  3K25 A;  1JZ2 A;  1YQ2 A;  2WW3 A;  2WVY A;  1RWH A;  1ULV A;  1DP0 A;  2WMK A;  3T0B A;  1JYW A;  1JZ3 A;  1RWA A;  1X1H A;  2E22 A;  4D6D A;  3DYO A;  4AQ0 A;  3OS7 A;  1JZ8 A;  1HM2 A;  3E7J A;  1YGA A;  3I3B A;  1N7N A;  2D73 A;  1HMW A;  2WDA A;  1LF9 A;  3VD5 A;  3Q1N A;  1J0N A;  4D6I A;  1RWF A;  2FUT A;  1EGU A;  1MMX A;  4D6J A;  1K1W A;  4BZG A;  2E24 A;  1NSM A;  1RWG A;  3IAP A;  1OJN A;  1SO0 A;  3DEC A;  2Q1F A;  5JMD A;  3T2Q A;  3E80 A;  3VD9 A;  1J0M A;  1LOH A;  4RNL A;  4TTG A;  1OJO A;  4OK4 A;  3NRE A;  1LUR A;  1C82 A;  3AFL A;  4MMI A;  1K1X A;  2HTA A;  4D72 A;  1F4A A; 
#chains in the Genus database with same CATH topology
 1I8Q A;  1KSC A;  1X9D A;  5AGD A;  3X3Z A;  2F7R A;  2JF4 A;  4GTQ B;  1G9G A;  3S9V A;  2ZL8 A;  3UD2 A;  3VDB A;  3DX0 A;  3T33 A;  3EJU A;  3WVF A;  3W7T A;  3T0U A;  3LOY A;  1D6U A;  4WVA A;  1N4Q B;  4YDE B;  3ECQ A;  2FUZ A;  2F0Y B;  5GW7 A;  3HXC B;  4DUX A;  2CIR A;  3W5M A;  1GA2 A;  2SQC A;  2WMI A;  2WW1 A;  3CZS A;  3SFY B;  1KSI A;  4KFE A;  3M78 A;  2WYI A;  3KII A;  5IL8 A;  4QT9 A;  1WMO A;  5GZK A;  3SX1 A;  1R33 A;  1IVX A;  4EL8 A;  4EV2 A;  2VN4 A;  3E34 B;  4TXT A;  3I3E A;  3Q7F B;  3ON6 A;  3CIH A;  1US1 A;  3E33 B;  1NS2 A;  1IVV A;  3M75 A;  3KBU C;  2XSG A;  4K35 A;  1N7O A;  3EU8 A;  1TQV A;  2V8J A;  4LNV A;  1W6K A;  3KQ4 A;  1HXK A;  1O6R A;  4D6G A;  3E73 A;  1WU5 A;  2R2L B;  2CFK A;  2G0D A;  3KSQ B;  2WCO A;  1O5M B;  2NOJ A;  2FV0 A;  3D3I A;  1IQY A;  3M7C A;  3SDR A;  1XWQ A;  1O6Q A;  2PMV A;  4WU0 A;  2V3N A;  5FOB B;  1S63 B;  1QWN A;  3VD4 A;  3HXD B;  3RX7 A;  2OW7 A;  3A0O A;  2G02 A;  5ILD A;  3WIW A;  3M7E A;  1X1J A;  4BOJ A;  4AYQ A;  1TU5 A;  3KSL B;  4OZW A;  3PGB A;  3WFA A;  1R76 A;  2F1A A;  2JKE A;  3WKG A;  1WMN A;  1CB8 A;  1DOG A;  3S4D A;  1FP3 A;  3EZ8 A;  1H36 A;  2GZ6 A;  4GTM B;  3W7S A;  1SPU A;  2WYH A;  4Q2B A;  2ZIR B;  1O1S B;  1N4S B;  4DOD A;  3AMO A;  2DRS A;  1H3A A;  1TN6 B;  2IEJ B;  4D4C A;  4D4B A;  5KKB A;  1HN0 A;  3X3X A;  1N1Z A;  4CJ0 A;  2FBA A;  1QAF A;  3T2P A;  2ONG A;  3S4A A;  1V7W A;  4FXG B;  1LF6 A;  3QR8 A;  3OBA A;  1O7D D;  3BS6 A;  1JCS B;  4XUV A;  3E32 B;  1N24 A;  2XQW A;  1G6I A;  2FV1 A;  2WW3 A;  3K11 A;  3DX3 A;  3HIG A;  1H37 A;  1NI1 B;  1WZZ A;  3X41 A;  1O1R B;  1GLM A;  1LTX B;  3S4C A;  4CJ1 A;  1JZ3 A;  1RWA A;  3DRA B;  1JYW A;  3Q78 B;  4GTR B;  4V1S A;  3PQI A;  1N23 A;  1HM2 A;  4AYR A;  4ZRQ A;  1IS9 A;  1IA6 A;  1HTY A;  2D73 A;  2WDA A;  3N0G A;  3WKF A;  4L9P B;  1NXC A;  3KN4 A;  1J0N A;  4D6I A;  5M7Y A;  5C05 A;  1TNU B;  1MMX A;  4D6J A;  4K3A A;  2F7Q A;  1R34 A;  5CZL A;  2VN7 A;  2E24 A;  3QT3 A;  2KXR A;  3D5S A;  4D4A A;  3T2Q A;  5IKH A;  5IL3 A;  2RGK A;  1GAI A;  1VD5 A;  3SAE A;  4TTG A;  3AFJ A;  1HZF A;  2CFG A;  2CWU A;  3AFL A;  1CLC A;  4MMI A;  1QAL A;  2HTA A;  5FO8 B;  1MMU A;  4KKJ A;  4FNP A;  3LVT A;  3EJS A;  3N0F A;  5FO7 B;  2F7O A;  2F6D A;  2OQE C;  1JYV A;  2KXS A;  1A2V A;  1GHQ A;  4D6E A;  3KBT C;  1NS8 A;  1D8E B;  1HN1 A;  2WY8 A;  1W5Z A;  1AV4 A;  4FNU A;  2ZIS B;  4BZF A;  2ZBL A;  3EQA A;  1W6G A;  1JYN A;  1H3C A;  1DYU A;  3GT5 A;  3SEP A;  3BUP A;  1HX9 A;  2QNO A;  4D1I A;  2XN1 A;  5EAS A;  3A3V A;  1WMP A;  1JCQ B;  3ANJ A;  2WMJ A;  3MUY 1;  3T08 A;  1WU6 A;  3H2W A;  4F10 A;  2WZS A;  1FT2 B;  1LXM A;  2CQT A;  1F9O A;  4LNG B;  1UMP A;  1W4N A;  4J5T A;  4GAX A;  4D4D A;  3SDV A;  1L7K A;  2OQE A;  1GXO A;  1C3D A;  1N7R A;  1NS7 A;  4FXK B;  3SDT A;  3W7X A;  1N7P A;  3QXQ A;  1V5C A;  4GL3 A;  3WKI A;  1Z45 A;  4BTW A;  4RNQ A;  1AVL A;  1JZ6 A;  1FT1 B;  3QFY A;  2YX9 A;  4F13 A;  1OAC A;  5ILJ A;  3T2O A;  1F4H A;  1N21 A;  4GTO B;  3NJV A;  4FNQ A;  3DSU B;  1H3B A;  1JYX A;  2AHG A;  4ONT A;  3DDG A;  3A24 A;  5A1A A;  2BRP A;  1TXK A;  1V7X A;  2WVX B;  1PX3 A;  4BTX A;  1HMU A;  1F9G A;  4OK2 A;  3BVT A;  1SA4 B;  1N22 A;  2H6H B;  2BED B;  4Z4J A;  1UI8 A;  2XWJ B;  4E1Y A;  1JCR B;  3C72 B;  4DUW A;  1N4P B;  3WUX A;  3QXF A;  1L7J A;  1QQF A;  2PNC A;  3D52 A;  4L0G A;  2ONH A;  1N20 A;  3HXE B;  3D4Z A;  1HXG A;  1H54 A;  3M02 A;  3OED A;  3OB8 A;  3BVX A;  1TNB B;  3NNB A;  3P5P A;  3REN A;  1LXK A;  3M76 A;  1RWC A;  1TQW A;  2F1B A;  1TQU A;  2WW2 A;  4DUV A;  3RX8 A;  4D6F A;  4D71 A;  2B4F A;  2JG0 A;  5IK9 A;  5JPM B;  5JMF A;  5ILK A;  1W7C A;  2F18 A;  3DCD A;  1JZ2 A;  4L6X A;  4GTS B;  1ULV A;  1TNO B;  1AVK A;  1DP0 A;  1KS8 A;  2WMK A;  5CD2 A;  3WIQ A;  2CWV A;  2W0Q A;  1X1H A;  2E22 A;  3F59 A;  4DLQ A;  4D6D A;  3DYO A;  4GTP B;  3OS7 A;  1YGA A;  4FNT A;  3WA3 A;  3BLC A;  4EHM B;  1HMW A;  1NL4 B;  3Q1N A;  1RWF A;  3EJR A;  2OOV C;  3D51 A;  1EGU A;  3Q73 B;  1K72 A;  3OXU A;  4TF4 A;  1DL2 A;  1NSM A;  1OJN A;  2JJB A;  2H6G B;  1F9D A;  2H6I B;  4MBG B;  3PZ3 B;  3QPF A;  1KRE A;  5GY3 A;  3VD9 A;  3DX1 A;  2J5C A;  4GTV B;  3ACT A;  5IKA A;  4ZRP A;  1L2A A;  1O1T B;  2I07 B;  2YFN A;  4D72 A;  1F4A A;  2V3P A;  3CV5 A;  3D4Y A;  1D6Y A;  3EJT A;  2WVZ A;  3H7L A;  3KLS A;  4DI5 A;  2EAE A;  2E2U A;  3MWX A;  1MMZ A;  3VSM A;  3DX2 A;  3VW5 A;  3E30 B;  2OOV A;  3VD3 A;  1IU7 A;  3ANK A;  4ZH5 A;  3T0D A;  2JKP A;  2Y74 A;  3SDQ A;  3NFV A;  1D6Z A;  3K5T A;  2WMI B;  2BRV X;  4KFD A;  4YDO B;  3DSX B;  3M73 A;  3PZ4 B;  1X1I A;  5DGQ A;  3RRS A;  2HTB A;  1KSD A;  3HXB B;  3ALA A;  3QG0 A;  1PX4 A;  1UI7 A;  3BUQ A;  2WVX A;  4KKI A;  3SDU A;  4FNR A;  3M00 A;  4D8O A;  1NSV A;  3SXX A;  1F1S A;  4V1R A;  2CIS A;  5IM1 A;  1N4R B;  1SNZ A;  3BVU A;  2OKX A;  1TQT A;  3M01 A;  3PZ1 B;  4WVC A;  3LZ9 A;  2ZXQ A;  4OZV A;  3VXD A;  3E1F 1;  1JZ5 A;  3G6J B;  2CFL A;  1O79 A;  3M71 A;  1L1Y A;  2AFA A;  4NEI A;  2JKA A;  2WO0 A;  2WW0 A;  3BVV A;  3IMH A;  4LNB B;  3MV1 1;  1H35 A;  4YCR A;  1FBO A;  3MUZ 1;  1N94 B;  3RSY A;  3DST B;  1LD7 B;  1CEM A;  1D8D B;  2GOX A;  3G4F A;  2OW6 A;  2XWB B;  4GTT B;  1SIH A;  3CZJ A;  5DGR A;  4KTP A;  3ACS A;  1MN0 A;  3PZ2 B;  2ZZR A;  1TNZ B;  5CA3 A;  2CFW A;  1KZP B;  1NC5 A;  3PMM A;  2C10 A;  4M76 A;  1H14 A;  2AHF A;  1GXM A;  1S64 B;  1NSU A;  3PYA A;  2XN0 A;  2XFG A;  3EUV B;  1KZO B;  3AMO B;  4D6H A;  4JJJ A;  3EU5 B;  2DRO A;  2BB6 A;  3E37 B;  3BUI A;  3QRY A;  1JZ7 A;  2EAB A;  1V7V A;  3SFX B;  1LD8 B;  1NSS A;  3HXF B;  4EV5 A;  3T0A A;  3QFZ A;  1EKM A;  1QAZ A;  4CE7 A;  1SII A;  3HI7 A;  4D6C A;  5ILI A;  2NVP A;  1GAH A;  3D50 A;  2WVY A;  1XWT A;  4FUS A;  3DSW B;  1KKT A;  4MU9 A;  3Q79 B;  4AQ0 A;  1JZ8 A;  2ALW A;  3S4B A;  3WC3 A;  3I3B A;  3UD1 A;  3P5R A;  3ANI A;  3G4D A;  3HII A;  3VD5 A;  4ZG8 A;  3PYB A;  2FUT A;  1K1W A;  1UT9 A;  3BUB A;  4BZG A;  3P2C A;  1O6H A;  2D1W A;  3X3Y A;  1H39 A;  3U7V A;  4DLO A;  5DHI A;  4LIX A;  2WY7 A;  3DPY B;  1LOH A;  5IK0 A;  5ILH A;  4RNL A;  3K7X A;  1JRQ A;  3MPH A;  4OK4 A;  1FCE A;  4AYO A;  1LUR A;  1N9E A;  1IVW A;  1TQS A;  2CFD A;  5FO9 B;  1K1X A;  3X40 A;  3BUD A;  4Q88 A;  1N95 B;  1PS3 A;  1JZ4 A;  1DCE B;  2P0V A;  4D1J A;  4ZH1 A;  4Z4L A;  3SQC A;  2A8Z A;  5IK6 A;  2WYN A;  2RI9 A;  2CG0 A;  1AGM A;  1W3Y A;  1RJO A;  4FNV A;  3H3K A;  3MV0 1;  1GXN A;  3M74 A;  2C11 A;  3VD7 A;  1FMI A;  1N7Q A;  2FUQ A;  3Q7A B;  5KBP A;  2CIQ A;  1HWW A;  1XW2 A;  2CQS A;  3RJ3 A;  1N1B A;  3QWT A;  3I3D A;  1OJM A;  3CZN A;  1JOV A;  1HCU A;  2WGQ A;  1H13 A;  1NKG A;  2V8K A;  3T09 A;  3X17 A;  1FO2 A;  1MMY A;  2WOF A;  1G9J A;  2Y73 A;  1KRF A;  3TF4 A;  1QX1 A;  2EAD A;  3DYM A;  3WIR A;  4AYP A;  3NBJ A;  1RW9 A;  1FBW A;  2DRR A;  1NS4 A;  3N9H A;  4BZE A;  3DSV B;  4FJQ A;  2EAC A;  4BZH A;  3DX4 A;  3EJQ A;  1TF4 A;  3QDE A;  3QT9 A;  2XHN A;  1W6J A;  2A73 B;  3DSS B;  2X03 A;  2GH4 A;  1K1Y A;  3CU7 A;  1KFG A;  3Q75 B;  2WII B;  4BOK A;  1WU4 A;  2E2T A;  2V8I A;  1IVU A;  3QSP A;  1IQX A;  1NSR A;  1QAK A;  1N9A B;  5E1Q A;  1PU4 A;  3GZK A;  3EJP A;  3VDC A;  2BT3 A;  1NSZ A;  4D94 A;  4MMH A;  1NS0 A;  3NJX A;  1HM3 A;  4KTR A;  3BGA A;  2ZQ0 A;  1IA7 A;  1HXC A;  1TN8 B;  2BBC A;  2WMG A;  2WMH A;  3VSN A;  1H12 A;  2D8L A;  3DYP A;  1HV6 A;  4KFF A;  3IAQ A;  3VDA A;  2B39 A;  2BRW A;  1JS4 A;  3BLB A;  3DDF A;  2H6F B;  2WOH A;  2CWT A;  2RI8 A;  1W2Z A;  2CG1 A;  1TN7 B;  1SA5 B;  2WMF A;  1RQ5 A;  3M7B A;  1TNY B;  1UG9 A;  5EAT A;  1MZC B;  1OJP A;  4OJZ A;  1QSJ A;  1QWU A;  5ILY A;  2DRQ A;  5ILZ A;  1NSX A;  3M72 A;  3J7H A;  4BTY A;  1W6C A;  1LVN A;  1HXA A;  3M77 A;  2D5J A;  2Z07 A;  3K25 A;  1GSZ A;  1FPP B;  1FO3 A;  3RX5 A;  1YQ2 A;  3W7U A;  2YFO A;  5EAU A;  2XN2 A;  1RWH A;  1X81 B;  4DOE A;  4UFC A;  3T0B A;  4FNS A;  1KWF A;  3WKH A;  3BVW A;  1V5D A;  3NBB A;  3W5N A;  2YIK A;  1SQC A;  3D5R A;  3E7J A;  4C1S A;  3TY1 A;  1N7N A;  2FYV A;  5JPN B;  3MI6 A;  2PN5 A;  1LF9 A;  3E6U A;  2E2V A;  1AYX A;  1FAE A;  1QBQ B;  3GLY A;  2BB5 A;  2RDY A;  3M7L A;  3X42 A;  3W7W A;  1RWG A;  5MEH A;  3IAP A;  1SO0 A;  5E2J A;  1RKY A;  5M7I A;  3DEC A;  2Q1F A;  5JMD A;  2WIN B;  5DHK A;  3E80 A;  4WVB A;  1J0M A;  2F7P A;  1G87 A;  1OJO A;  3NRE A;  1C82 A;  3WA2 X; 
#chains in the Genus database with same CATH homology
 1I8Q A;  1MMU A;  1JZ4 A;  2WVZ A;  3MWX A;  1JYV A;  1MMZ A;  3VSM A;  1W3Y A;  4FNV A;  3MV0 1;  4D6E A;  3VDB A;  3VD3 A;  1NS8 A;  3VD7 A;  3WVF A;  2FUQ A;  1N7Q A;  1HN1 A;  2JKP A;  2CIQ A;  3ECQ A;  3NFV A;  4DUX A;  2WMI B;  2BRV X;  4BZF A;  2CIR A;  1X1I A;  2WMI A;  2HTB A;  3I3D A;  1JYN A;  1OJM A;  2WW1 A;  1JOV A;  3SEP A;  1PX4 A;  1NKG A;  2WVX A;  3T09 A;  1MMY A;  3T0D A;  2WMJ A;  3T08 A;  3MUY 1;  1NSV A;  3DYM A;  1F1S A;  4F10 A;  1RW9 A;  1NS4 A;  2CIS A;  2WZS A;  1LXM A;  4BZE A;  1SNZ A;  3I3E A;  4BZH A;  4J5T A;  1NS2 A;  2XHN A;  2ZXQ A;  1L7K A;  4OZV A;  1N7R A;  2X03 A;  2XSG A;  1K1Y A;  1NS7 A;  1N7O A;  3E1F 1;  1JZ5 A;  1N7P A;  1Z45 A;  2JKA A;  4NEI A;  2WW0 A;  3IMH A;  1JZ6 A;  3MV1 1;  4F13 A;  1NSR A;  4D6G A;  3T2O A;  3MUZ 1;  5E1Q A;  1F4H A;  3NJV A;  2WCO A;  1JYX A;  3VDC A;  1NSZ A;  3A24 A;  4MMH A;  5A1A A;  2BRP A;  1NS0 A;  3NJX A;  1HM3 A;  1TXK A;  2WVX B;  1PX3 A;  3BGA A;  2ZQ0 A;  3VD4 A;  1HMU A;  3A0O A;  2WMG A;  3CZJ A;  2WMH A;  4OK2 A;  1F9G A;  1MN0 A;  1X1J A;  3VSN A;  3DYP A;  1HV6 A;  4OZW A;  3IAQ A;  4E1Y A;  3VDA A;  3WFA A;  4DUW A;  2JKE A;  2BRW A;  1L7J A;  1NSU A;  1CB8 A;  2WMF A;  3OB8 A;  4D6H A;  1UG9 A;  3NNB A;  1OJP A;  4OJZ A;  1JZ7 A;  1LXK A;  4DUV A;  1RWC A;  1NSS A;  2WW2 A;  4D6F A;  1NSX A;  3J7H A;  4D71 A;  3T0A A;  1HN0 A;  1QAZ A;  5JMF A;  3DCD A;  3T2P A;  3OBA A;  1LF6 A;  4D6C A;  3BS6 A;  3K25 A;  1JZ2 A;  1YQ2 A;  2WW3 A;  2WVY A;  1RWH A;  1ULV A;  1DP0 A;  2WMK A;  3T0B A;  1JYW A;  1JZ3 A;  1RWA A;  1X1H A;  2E22 A;  4D6D A;  3DYO A;  4AQ0 A;  3OS7 A;  1JZ8 A;  3TY1 A;  1HM2 A;  3E7J A;  1YGA A;  3I3B A;  1N7N A;  3BLC A;  2D73 A;  1HMW A;  2WDA A;  1LF9 A;  3VD5 A;  3Q1N A;  1J0N A;  4D6I A;  1RWF A;  2FUT A;  1EGU A;  1MMX A;  4D6J A;  1K1W A;  4BZG A;  2E24 A;  1NSM A;  1RWG A;  3IAP A;  1OJN A;  1SO0 A;  3DEC A;  2Q1F A;  5JMD A;  3T2Q A;  3E80 A;  3VD9 A;  1J0M A;  1LOH A;  4RNL A;  4TTG A;  1OJO A;  4OK4 A;  3NRE A;  1LUR A;  1C82 A;  3AFL A;  4MMI A;  1K1X A;  2HTA A;  4D72 A;  1F4A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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