1OJOA

Specificity and mechanism of streptococcus pneumoniae hyaluronate lyase: complex of the tyr408phe mutant with 4-sulphated chondroitin disaccharide
Total Genus 255
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
255
sequence length
722
structure length
722
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNRDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title Structures of Streptococcus Pneumoniae Hyaluronate Lyase in Complex with Chondroitin and Chondroitin Sulfate Disaccharides: Insights Into Specificity and Mechanism of Action
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 255
structure length 722
sequence length 722
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2003-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1ojoA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1ojoA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1ojoA01
1MN0A 3E7JA 1HMWA 3T2PA 1MMZA 1HV6A 1OJMA 4AQ0A 4FNVA 1CB8A 4D6IA 1NSXA 2WW3A 3OB8A 3SEPA 1RWFA 3E80A 2XSGA 4BZHA 1SNZA 2BRVX 4F10A 1TXKA 1EGUA 1ULVA 3MUZ1 2WVXA 1NKGA 3T2OA 1RWAA 3I3EA 1YGAA 1NS2A 1HMUA 1J0MA 1LOHA 4OZWA 2ZQ0A 3K25A 3NJVA 1K1YA 3VD9A 1HM3A 1N7OA 4E1YA 3DYOA 3ECQA 3VSNA 5E1QA 2E24A 4D6GA 1JYVA 1JZ7A 3MUY1 3BGAA 2WMJA 1N7RA 1RWGA 1L7KA 2BRWA 2E22A 1NSMA 1MMYA 2WMGA 3DYMA 1MMUA 2FUQA 4D6CA 3E1F1 1J0NA 3NREA 3OS7A 2D73A 3T0BA 4D6JA 3WFAA 1PX3A 3VSMA 3I3DA 3T0AA 2FUTA 3T09A 3T08A 1RWHA 3T2QA 4DUVA 4D72A 1HM2A 1JZ2A 1RW9A 1HN1A 1NS8A 5JMDA 4RNLA 3VD3A 1LURA 3VDBA 1JZ8A 1JZ4A 1NSZA 3MV01 2X03A 5JMFA 2JKEA 1F1SA 1W3YA 4MMHA 1UG9A 1C82A 3CZJA 1K1XA 1JOVA 1X1JA 3NFVA 1QAZA 4OZVA 2WMIA 1YQ2A 3VD5A 1LXKA 1SO0A 4NEIA 2WCOA 4DUXA 1F9GA 4MMIA 1LXMA 2CIRA 2WW0A 3AFLA 2HTAA 4D6DA 1L7JA 1F4AA 3VD7A 1N7PA 1OJPA 2XHNA 3DCDA 1HN0A 1N7QA 3J7HA 1OJOA 2WDAA 1JYNA 4OK4A 3A0OA 4BZEA 1NSRA 2WMKA 3DECA 4D6FA 4F13A 1JZ6A 1X1HA 2HTBA 1MMXA 2WW2A 3MWXA 3DYPA 1DP0A 2WVYA 1LF9A 2WMFA 1X1IA 2Q1FA 4OJZA 4D71A 1K1WA 1F4HA 4OK2A 3Q1NA 4D6EA 4BZGA 3VDCA 1Z45A 4TTGA 3A24A 2WVXB 4BZFA 5A1AA 1JZ3A 1LF6A 3IAQA 1NSVA 2CISA 1JZ5A 2JKAA 1PX4A 4D6HA 1I8QA 2CIQA 1NS7A 1NSUA 2JKPA 2WVZA 3I3BA 1JYXA 3IAPA 4DUWA 3NNBA 1NS0A 2ZXQA 2WMHA 1NS4A 1N7NA 3VD4A 3NJXA 2BRPA 2WW1A 2WZSA 3IMHA 2WMIB 3VDAA 3MV11 1OJNA 3T0DA 3OBAA 1JYWA 1RWCA 1NSSA
chains in the Genus database with same CATH superfamily
3QR8A 4D1IA 1MN0A 4QT9A 3QXFA 1MMZA 3DSWB 3MPHA 1US1A 1CB8A 2XWBB 2WW3A 1HXKA 1DOGA 2VN4A 1SNZA 2WVXA 1NKGA 3ANKA 1KKTA 2I07B 1CEMA 1N4SB 1HMUA 1N24A 3Q75B 1TNYB 4GAXA 3TY1A 4EL8A 1LD7B 2ZQ0A 1UMPA 3NBBA 3ACTA 2PN5A 1HM3A 5DGRA 1N7OA 4E1YA 3MI6A 4YCRA 1NI1B 2AHGA 3PZ1B 1KSCA 5E1QA 1O79A 2E24A 3RENA 1JYVA 3DX0A 3M7CA 3PZ3B 3E73A 3K5TA 2AFAA 5DHKA 3HXBB 1W7CA 1N7RA 3AMOA 3DX1A 2F7PA 1N4RB 1IS9A 3E30B 4DLQA 4D4DA 1NSMA 2RI9A 2V8JA 2FUQA 3T0BA 1O1TB 1W6CA 1WZZA 2XQWA 3BVTA 3T0AA 2FBAA 1RWHA 1GLMA 3W5NA 3T2QA 1WU4A 3KSQB 4L0GA 1H12A 3LVTA 4DODA 1HN1A 4GTPB 1VD5A 1LURA 1SQCA 1O1RB 5JPMB 3D4ZA 3H7LA 4TXTA 1JZ4A 5IM1A 3MV01 1N9AB 1W3YA 1EKMA 1XWTA 3X41A 1UG9A 1HZFA 3CZJA 2Y74A 3D3IA 1K1XA 2BB6A 3NFVA 1G87A 3VD5A 1N20A 3T0UA 3DPYB 1LTXB 1LVNA 2RGKA 3D4YA 2WCOA 5IKAA 4LNBB 1L1YA 1FT2B 4WU0A 1H36A 1R76A 5IK0A 2CIRA 2KXRA 2E2VA 2WW0A 4DLOA 1LD8B 4D1JA 5FO7B 2ZIRB 4D4CA 1WU5A 3DX3A 3SAEA 3J7HA 5ILYA 2WDAA 1H39A 2F6DA 3QWTA 4OK4A 1IVUA 3DSXB 1IQYA 1WMOA 3A0OA 2WINB 2V8IA 1IU7A 1NSRA 3DECA 3M72A 5M7YA 1FCEA 1X1HA 4KFEA 2D8LA 1MMXA 3HIIA 5IL3A 4FNQA 3DYPA 2WVYA 3CV5A 4BOKA 3Q7AB 4D71A 1K1WA 1F4HA 2H6FB 4BZFA 1V7WA 5DGQA 2CISA 3X40A 2ONHA 4CJ1A 3LOYA 4D6HA 4FNSA 1F9DA 4WVAA 2JKPA 1IVVA 2IEJB 1JYXA 3IAPA 2V3NA 3E32B 3DDGA 1D8DB 3A3VA 3UD2A 2FYVA 1N7NA 3WKGA 2PNCA 3P2CA 2WW1A 2G0DA 3RX7A 1GHQA 3BVXA 3VDAA 2F7OA 1OJNA 3OBAA 1GXNA 3SFXB 2J5CA 3W7WA 1HMWA 2CFKA 3T2PA 1OJMA 4BTWA 4FNVA 3PZ2B 2CWVA 3M7BA 4Z4JA 4D6IA 1NSXA 2WOFA 3SEPA 3E80A 2XSGA 2V3PA 4D4AA 4F10A 1GAHA 1W2ZA 2Y73A 4GTVB 3T2OA 1FMIA 3I3EA 1QWNA 3H2WA 3Q73B 1J0MA 2OW6A 3QT9A 4FNTA 1K1YA 1QWUA 1JCSB 3QSPA 1N9EA 3EZ8A 2NOJA 3DYOA 3VSNA 3P5PA 3K7XA 3M76A 3ANJA 4D6GA 3P5RA 3QFZA 2EADA 1SIHA 2YFOA 3MUY1 4GTOB 3W7UA 4FNUA 1N23A 5FO8B 3PYAA 2B39A 4MBGB 2OKXA 4KKJA 2E22A 1TU5A 1IQXA 1SA5B 2H6GB 2XWJB 1N1ZA 2BBCA 2EACA 3GLYA 4GL3A 1V5CA 4LNGB 4ONTA 5CD2A 4D6CA 2JJBA 3D5SA 1KREA 3G4FA 4M76A 1HTYA 4D6JA 1QAKA 3EQAA 1PX3A 2D73A 3VSMA 3I3DA 2FUTA 3EJTA 2F1BA 3M7LA 1W6JA 4DUVA 4FNRA 2C11A 3W7XA 2XN1A 3ANIA 3DX2A 3CU7A 4AYPA 3VD3A 3DDFA 1JZ8A 3VDBA 1XW2A 3QXQA 2YFNA 2DROA 4BTXA 1F1SA 1C82A 5GZKA 1TNOB 1UT9A 4OZVA 1YQ2A 4V1RA 1SO0A 1O7DD 3W7TA 3BVWA 4TF4A 1MZCB 3E33B 3QPFA 3D52A 4L9PB 4UFCA 1IA7A 2XN2A 3M7EA 1F9OA 2SQCA 1G9GA 1LXMA 1FBWA 2FV1A 3WIRA 5KKBA 2YIKA 2GH4A 3AFLA 2XN0A 1FT1B 5IL8A 1AVLA 1F4AA 5KBPA 3WKHA 2F18A 1N7QA 1KZOB 1OJOA 5GY3A 1S63B 1XWQA 1AYXA 3LZ9A 3WKFA 1JYNA 3HXFB 1CLCA 2PMVA 2H6IB 1WMNA 2EABA 4D6FA 3M74A 2RDYA 5MEHA 4GTTB 4AYRA 1R33A 3EJRA 1JZ6A 1KSDA 2WW2A 2DRRA 1W4NA 1DP0A 3VD9A 4WVBA 3QRYA 1X9DA 2WMFA 2F7RA 3Q1NA 1N94B 4OK2A 4D6EA 1N21A 1PS3A 4BZGA 2WYIA 3M73A 5JPNB 3M77A 3E37B 1JZ5A 2JKAA 4FXKB 3DRAB 3NBJA 1SA4B 2CIQA 3WKIA 2CFGA 4DUWA 3SDTA 1WU6A 3N0GA 3HXDB 4ZG8A 1NXCA 1UI7A 2DRSA 2W0QA 2BRPA 4GTSB 3IMHA 1N4PB 2WMIB 3X3XA 3MV11 3T0DA 1NL4B 4KTRA 3BUPA 1JYWA 4Q2BA 3WVFA 3HIGA 1O6HA 1HXCA 4AQ0A 1G6IA 1HV6A 4ZH5A 1TN6B 2FUZA 1H13A 1TQSA 3WA2X 2EAEA 2OW7A 1H37A 1JZ2A 5ILDA 3BUQA 3F59A 2OOVA 3EJPA 3M02A 3OB8A 2G02A 1O1SB 3M75A 1W6KA 3GZKA 1RWAA 3N9HA 1WMPA 2CG1A 3EU5B 2DRQA 3RX8A 1NS2A 3CIHA 5GW7A 1LOHA 4FJQA 3KLSA 3KN4A 4AYQA 3QT3A 3TF4A 3K25A 3NJVA 3DSUB 5DHIA 2A8ZA 3ACSA 3ECQA 3BLBA 4GTMB 1JZ7A 3BGAA 3BUBA 2WMJA 3PYBA 4EV5A 2WYHA 1RWGA 3QFYA 1TQWA 5C05A 2GOXA 1TQTA 1V7VA 2WMGA 3UD1A 1D6YA 1JRQA 1MMUA 3OS7A 1OACA 3T08A 1FP3A 4L6XA 4RNQA 1AVKA 3HI7A 3OXUA 1HM2A 2D1WA 4YDOB 1C3DA 3KBUC 2XFGA 1IA6A 3VXDA 1NS8A 2RI8A 1RJOA 4KTPA 4C1SA 3SFYB 1NSZA 3RRSA 2X03A 4CJ0A 2JKEA 3PGBA 4EV2A 2BT3A 1KFGA 4K35A 1JOVA 1X1JA 2E2TA 3KBTC 2F7QA 2QNOA 2CFDA 1TN7B 4MU9A 4NEIA 1KWFA 1HXAA 5IK6A 4YDEB 4DUXA 1A2VA 3ON6A 3SDRA 1F9GA 4GTRB 3AFJA 2WIIB 1AV4A 3QG0A 3SDUA 3N0FA 1S64B 1IVXA 4FUSA 1H3CA 4D6DA 3VD7A 2Z07A 1N7PA 1OJPA 2VN7A 1QQFA 1GAIA 2YX9A 5FO9B 2ZISB 4KFDA 4KFFA 5IK9A 5FOBB 1GXOA 2ALWA 4F13A 1O5MB 2H6HB 1AGMA 2HTBA 1TNBB 1H54A 3MWXA 4FXGB 3S4DA 3M71A 1V5DA 1X1IA 2Q1FA 2B4FA 1PU4A 3VDCA 2ONGA 1Z45A 2WYNA 4TTGA 1TQUA 1JZ3A 1LF6A 1FPPB 3U7VA 1NSVA 5M7IA 3D5RA 3M78A 1PX4A 4Z4LA 3RSYA 3D50A 2JG0A 1I8QA 3G6JB 3GT5A 2FV0A 1NSUA 1GXMA 2CWUA 2BEDB 2WVZA 3QDEA 1FAEA 3Q79B 2NVPA 1D6UA 1HWWA 3S4CA 1NS0A 1N95B 2OOVC 2ZXQA 2CQSA 2WMHA 1IVWA 1NS4A 1KSIA 3X42A 1RKYA 3VD4A 3PQIA 1QALA 3M00A 3EJUA 1NC5A 3H3KA 1DYUA 4D4BA 1RWCA 1NSSA 1H3AA 2KXSA 4ZRQA 3E7JA 2CG0A 3SXXA 2ZBLA 4FNPA 4BOJA 3BUDA 2OQEC 4LNVA 1RWFA 3S4AA 4Q88A 4BZHA 2BRVX 1TXKA 1ULVA 1EGUA 5ILIA 5ILZA 2E2UA 3MUZ1 3CZSA 1R34A 2V8KA 1K72A 1YGAA 5ILHA 1QSJA 3SX1A 4OZWA 3PMMA 1JCRB 4GTQB 5EASA 5EAUA 3ALAA 4ZRPA 1TNZB 1O6RA 1QAFA 3K11A 5EATA 3RJ3A 2R2LB 2GZ6A 3Q78B 3WC3A 3Q7FB 1KS8A 1N1BA 4AYOA 1H3BA 1N22A 1RQ5A 3DX4A 2A73B 1QBQB 3M01A 1X81B 1L7KA 2BRWA 3C72B 4JJJA 1TN8B 3DYMA 1W5ZA 3E1F1 3DSSB 3NREA 1J0NA 1SIIA 3WFAA 4CE7A 1HX9A 3WIQA 3HXEB 4V1SA 3T09A 4D72A 2F1AA 1FO2A 1JS4A 5IKHA 3G4DA 3X17A 1RW9A 2WGQA 3KIIA 4EHMB 2ZL8A 5JMDA 4RNLA 2JF4A 5AGDA 3PZ4B 3T33A 3WUXA 2C10A 2BB5A 5JMFA 1MMYA 4MMHA 3EUVB 1JCQB 4DOEA 3E34B 3SDQA 3E6UA 2OQEA 2WO0A 1DL2A 1QAZA 1N4QB 2WY7A 2WMIA 2ZZRA 1LXKA 5E2JA 3WIWA 1UI8A 1V7XA 3KSLB 3KQ4A 3BVVA 1HCUA 1GSZA 4DI5A 1FO3A 3BUIA 1H35A 3X3ZA 4MMIA 1HXGA 1KRFA 2CQTA 2AHFA 2HTAA 3CZNA 1FBOA 3VW5A 2P0VA 4WVCA 1L7JA 3OEDA 3X3YA 3DSVB 4KKIA 2XHNA 3DCDA 1HN0A 5ILJA 1KZPB 3WA3A 1TQVA 2WOHA 2CWTA 3EJQA 4BZEA 2D5JA 5CZLA 2WMKA 1DCEB 1SPUA 3D51A 2CFWA 4K3AA 3W5MA 4LIXA 3EU8A 1W6GA 4XUVA 3BS6A 1D6ZA 1LF9A 4OJZA 3S9VA 2WY8A 4D8OA 1O6QA 3S4BA 1D8EB 3A24A 2WVXB 5A1AA 2CFLA 3EJSA 4D94A 3IAQA 3SQCA 4BTYA 4J5TA 4ZH1A 1TNUB 5CA3A 1NS7A 3BLCA 3I3BA 3HXCB 3DSTB 3NNBA 3BVUA 3RX5A 1H14A 1QX1A 3NJXA 2WZSA 1G9JA 1TF4A 1GA2A 3SDVA 5ILKA 3W7SA 2F0YB 3AMOB 1L2AA
chains in the Genus database with same CATH topology
1MN0A 3WVFA 3E7JA 1HMWA 3T2PA 1MMZA 1HV6A 1OJMA 4AQ0A 4FNVA 1CB8A 4D6IA 1NSXA 2WW3A 3OB8A 3SEPA 1RWFA 3E80A 2XSGA 4BZHA 1SNZA 2BRVX 4F10A 1TXKA 1EGUA 1ULVA 3MUZ1 2WVXA 1NKGA 3T2OA 1RWAA 3I3EA 1YGAA 1NS2A 1HMUA 1J0MA 1LOHA 3TY1A 4OZWA 2ZQ0A 3K25A 3NJVA 1K1YA 3VD9A 1HM3A 1N7OA 4E1YA 3DYOA 3ECQA 3VSNA 5E1QA 2E24A 4D6GA 1JYVA 1JZ7A 3MUY1 3BGAA 2WMJA 1N7RA 1RWGA 1L7KA 2BRWA 2E22A 1NSMA 1MMYA 2WMGA 3DYMA 1MMUA 2FUQA 4D6CA 3E1F1 1J0NA 3NREA 3OS7A 2D73A 3T0BA 4D6JA 3WFAA 1PX3A 3VSMA 3I3DA 3T0AA 2FUTA 3T09A 3T08A 1RWHA 3T2QA 4DUVA 4D72A 1HM2A 1JZ2A 1RW9A 1HN1A 1NS8A 5JMDA 4RNLA 3VD3A 1LURA 3VDBA 1JZ8A 1JZ4A 1NSZA 3MV01 2X03A 5JMFA 2JKEA 1F1SA 1W3YA 4MMHA 1UG9A 1C82A 3CZJA 1K1XA 1JOVA 1X1JA 3NFVA 1QAZA 4OZVA 2WMIA 1YQ2A 3VD5A 1LXKA 1SO0A 4NEIA 2WCOA 4DUXA 1F9GA 4MMIA 1LXMA 2CIRA 2WW0A 3AFLA 2HTAA 4D6DA 1L7JA 1F4AA 3VD7A 1N7PA 1OJPA 2XHNA 3DCDA 1HN0A 1N7QA 3J7HA 1OJOA 2WDAA 1JYNA 4OK4A 3A0OA 4BZEA 1NSRA 2WMKA 3DECA 4D6FA 4F13A 1JZ6A 1X1HA 2HTBA 1MMXA 2WW2A 3MWXA 3BS6A 1DP0A 2WVYA 3DYPA 1LF9A 2WMFA 1X1IA 2Q1FA 4OJZA 4D71A 1K1WA 1F4HA 4OK2A 3Q1NA 4D6EA 4BZGA 3VDCA 1Z45A 4TTGA 3A24A 2WVXB 4BZFA 5A1AA 1JZ3A 1LF6A 3IAQA 1NSVA 2CISA 1JZ5A 2JKAA 1PX4A 4D6HA 1I8QA 4J5TA 2CIQA 1NS7A 1NSUA 2JKPA 2WVZA 3BLCA 3I3BA 1JYXA 3IAPA 4DUWA 3NNBA 1NS0A 2ZXQA 2WMHA 1NS4A 1N7NA 3VD4A 3NJXA 2BRPA 2WW1A 2WZSA 3IMHA 2WMIB 3VDAA 3MV11 1OJNA 3T0DA 3OBAA 1JYWA 1RWCA 1NSSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MN0 A;  3E7J A;  1HMW A;  3T2P A;  1MMZ A;  1HV6 A;  1OJM A;  4AQ0 A;  4FNV A;  1CB8 A;  4D6I A;  1NSX A;  2WW3 A;  3OB8 A;  3SEP A;  1RWF A;  3E80 A;  2XSG A;  4BZH A;  1SNZ A;  2BRV X;  4F10 A;  1TXK A;  1EGU A;  1ULV A;  3MUZ 1;  2WVX A;  1NKG A;  3T2O A;  1RWA A;  3I3E A;  1YGA A;  1NS2 A;  1HMU A;  1J0M A;  1LOH A;  4OZW A;  2ZQ0 A;  3K25 A;  3NJV A;  1K1Y A;  3VD9 A;  1HM3 A;  1N7O A;  4E1Y A;  3DYO A;  3ECQ A;  3VSN A;  5E1Q A;  2E24 A;  4D6G A;  1JYV A;  1JZ7 A;  3MUY 1;  3BGA A;  2WMJ A;  1N7R A;  1RWG A;  1L7K A;  2BRW A;  2E22 A;  1NSM A;  1MMY A;  2WMG A;  3DYM A;  1MMU A;  2FUQ A;  4D6C A;  3E1F 1;  1J0N A;  3NRE A;  3OS7 A;  2D73 A;  3T0B A;  4D6J A;  3WFA A;  1PX3 A;  3VSM A;  3I3D A;  3T0A A;  2FUT A;  3T09 A;  3T08 A;  1RWH A;  3T2Q A;  4DUV A;  4D72 A;  1HM2 A;  1JZ2 A;  1RW9 A;  1HN1 A;  1NS8 A;  5JMD A;  4RNL A;  3VD3 A;  1LUR A;  3VDB A;  1JZ8 A;  1JZ4 A;  1NSZ A;  3MV0 1;  2X03 A;  5JMF A;  2JKE A;  1F1S A;  1W3Y A;  4MMH A;  1UG9 A;  1C82 A;  3CZJ A;  1K1X A;  1JOV A;  1X1J A;  3NFV A;  1QAZ A;  4OZV A;  2WMI A;  1YQ2 A;  3VD5 A;  1LXK A;  1SO0 A;  4NEI A;  2WCO A;  4DUX A;  1F9G A;  4MMI A;  1LXM A;  2CIR A;  2WW0 A;  3AFL A;  2HTA A;  4D6D A;  1L7J A;  1F4A A;  3VD7 A;  1N7P A;  1OJP A;  2XHN A;  3DCD A;  1HN0 A;  1N7Q A;  3J7H A;  1OJO A;  2WDA A;  1JYN A;  4OK4 A;  3A0O A;  4BZE A;  1NSR A;  2WMK A;  3DEC A;  4D6F A;  4F13 A;  1JZ6 A;  1X1H A;  2HTB A;  1MMX A;  2WW2 A;  3MWX A;  3DYP A;  1DP0 A;  2WVY A;  1LF9 A;  2WMF A;  1X1I A;  2Q1F A;  4OJZ A;  4D71 A;  1K1W A;  1F4H A;  4OK2 A;  3Q1N A;  4D6E A;  4BZG A;  3VDC A;  1Z45 A;  4TTG A;  3A24 A;  2WVX B;  4BZF A;  5A1A A;  1JZ3 A;  1LF6 A;  3IAQ A;  1NSV A;  2CIS A;  1JZ5 A;  2JKA A;  1PX4 A;  4D6H A;  1I8Q A;  2CIQ A;  1NS7 A;  1NSU A;  2JKP A;  2WVZ A;  3I3B A;  1JYX A;  3IAP A;  4DUW A;  3NNB A;  1NS0 A;  2ZXQ A;  2WMH A;  1NS4 A;  1N7N A;  3VD4 A;  3NJX A;  2BRP A;  2WW1 A;  2WZS A;  3IMH A;  2WMI B;  3VDA A;  3MV1 1;  1OJN A;  3T0D A;  3OBA A;  1JYW A;  1RWC A;  1NSS A; 
#chains in the Genus database with same CATH topology
 3QR8 A;  4D1I A;  1MN0 A;  4QT9 A;  3QXF A;  1MMZ A;  3DSW B;  3MPH A;  1US1 A;  1CB8 A;  2XWB B;  2WW3 A;  1HXK A;  1DOG A;  2VN4 A;  1SNZ A;  2WVX A;  1NKG A;  3ANK A;  1KKT A;  2I07 B;  1CEM A;  1N4S B;  1HMU A;  1N24 A;  3Q75 B;  1TNY B;  4GAX A;  3TY1 A;  4EL8 A;  1LD7 B;  2ZQ0 A;  1UMP A;  3NBB A;  3ACT A;  2PN5 A;  1HM3 A;  5DGR A;  1N7O A;  4E1Y A;  3MI6 A;  4YCR A;  1NI1 B;  2AHG A;  3PZ1 B;  1KSC A;  5E1Q A;  1O79 A;  2E24 A;  3REN A;  1JYV A;  3DX0 A;  3M7C A;  3PZ3 B;  3E73 A;  3K5T A;  2AFA A;  5DHK A;  3HXB B;  1W7C A;  1N7R A;  3AMO A;  3DX1 A;  2F7P A;  1N4R B;  1IS9 A;  3E30 B;  4DLQ A;  4D4D A;  1NSM A;  2RI9 A;  2V8J A;  2FUQ A;  3T0B A;  1O1T B;  1W6C A;  1WZZ A;  2XQW A;  3BVT A;  3T0A A;  2FBA A;  1RWH A;  1GLM A;  3W5N A;  3T2Q A;  1WU4 A;  3KSQ B;  4L0G A;  1H12 A;  3LVT A;  4DOD A;  1HN1 A;  4GTP B;  1VD5 A;  1LUR A;  1SQC A;  1O1R B;  5JPM B;  3D4Z A;  3H7L A;  4TXT A;  1JZ4 A;  5IM1 A;  3MV0 1;  1N9A B;  1W3Y A;  1EKM A;  1XWT A;  3X41 A;  1UG9 A;  1HZF A;  3CZJ A;  2Y74 A;  3D3I A;  1K1X A;  2BB6 A;  3NFV A;  1G87 A;  3VD5 A;  1N20 A;  3T0U A;  3DPY B;  1LTX B;  1LVN A;  2RGK A;  3D4Y A;  2WCO A;  5IKA A;  4LNB B;  1L1Y A;  1FT2 B;  4WU0 A;  1H36 A;  1R76 A;  5IK0 A;  2CIR A;  2KXR A;  2E2V A;  2WW0 A;  4DLO A;  1LD8 B;  4D1J A;  5FO7 B;  2ZIR B;  4D4C A;  1WU5 A;  3DX3 A;  3SAE A;  3J7H A;  5ILY A;  2WDA A;  1H39 A;  2F6D A;  3QWT A;  4OK4 A;  1IVU A;  3DSX B;  1IQY A;  1WMO A;  3A0O A;  2WIN B;  2V8I A;  1IU7 A;  1NSR A;  3DEC A;  3M72 A;  5M7Y A;  1FCE A;  1X1H A;  4KFE A;  2D8L A;  1MMX A;  3HII A;  5IL3 A;  4FNQ A;  3DYP A;  2WVY A;  3CV5 A;  4BOK A;  3Q7A B;  4D71 A;  1K1W A;  1F4H A;  2H6F B;  4BZF A;  1V7W A;  5DGQ A;  2CIS A;  3X40 A;  2ONH A;  4CJ1 A;  3LOY A;  4D6H A;  4FNS A;  1F9D A;  4WVA A;  2JKP A;  1IVV A;  2IEJ B;  1JYX A;  3IAP A;  2V3N A;  3E32 B;  3DDG A;  1D8D B;  3A3V A;  3UD2 A;  2FYV A;  1N7N A;  3WKG A;  2PNC A;  3P2C A;  2WW1 A;  2G0D A;  3RX7 A;  1GHQ A;  3BVX A;  3VDA A;  2F7O A;  1OJN A;  3OBA A;  1GXN A;  3SFX B;  2J5C A;  3W7W A;  1HMW A;  2CFK A;  3T2P A;  1OJM A;  4BTW A;  4FNV A;  3PZ2 B;  2CWV A;  3M7B A;  4Z4J A;  4D6I A;  1NSX A;  2WOF A;  3SEP A;  3E80 A;  2XSG A;  2V3P A;  4D4A A;  4F10 A;  1GAH A;  1W2Z A;  2Y73 A;  4GTV B;  3T2O A;  1FMI A;  3I3E A;  1QWN A;  3H2W A;  3Q73 B;  1J0M A;  2OW6 A;  3QT9 A;  4FNT A;  1K1Y A;  1QWU A;  1JCS B;  3QSP A;  1N9E A;  3EZ8 A;  2NOJ A;  3DYO A;  3VSN A;  3P5P A;  3K7X A;  3M76 A;  3ANJ A;  4D6G A;  3P5R A;  3QFZ A;  2EAD A;  1SIH A;  2YFO A;  3MUY 1;  4GTO B;  3W7U A;  4FNU A;  1N23 A;  5FO8 B;  3PYA A;  2B39 A;  4MBG B;  2OKX A;  4KKJ A;  2E22 A;  1TU5 A;  1IQX A;  1SA5 B;  2H6G B;  2XWJ B;  1N1Z A;  2BBC A;  2EAC A;  3GLY A;  4GL3 A;  1V5C A;  4LNG B;  4ONT A;  5CD2 A;  4D6C A;  2JJB A;  3D5S A;  1KRE A;  3G4F A;  4M76 A;  1HTY A;  4D6J A;  1QAK A;  3EQA A;  1PX3 A;  2D73 A;  3VSM A;  3I3D A;  2FUT A;  3EJT A;  2F1B A;  3M7L A;  1W6J A;  4DUV A;  4FNR A;  2C11 A;  3W7X A;  2XN1 A;  3ANI A;  3DX2 A;  3CU7 A;  4AYP A;  3VD3 A;  3DDF A;  1JZ8 A;  3VDB A;  1XW2 A;  3QXQ A;  2YFN A;  2DRO A;  4BTX A;  1F1S A;  1C82 A;  5GZK A;  1TNO B;  1UT9 A;  4OZV A;  1YQ2 A;  4V1R A;  1SO0 A;  1O7D D;  3W7T A;  3BVW A;  4TF4 A;  1MZC B;  3E33 B;  3QPF A;  3D52 A;  4L9P B;  4UFC A;  1IA7 A;  2XN2 A;  3M7E A;  1F9O A;  2SQC A;  1G9G A;  1LXM A;  1FBW A;  2FV1 A;  3WIR A;  5KKB A;  2YIK A;  2GH4 A;  3AFL A;  2XN0 A;  1FT1 B;  5IL8 A;  1AVL A;  1F4A A;  5KBP A;  3WKH A;  2F18 A;  1N7Q A;  1KZO B;  1OJO A;  5GY3 A;  1S63 B;  1XWQ A;  1AYX A;  3LZ9 A;  3WKF A;  1JYN A;  3HXF B;  1CLC A;  2PMV A;  2H6I B;  1WMN A;  2EAB A;  4D6F A;  3M74 A;  2RDY A;  5MEH A;  4GTT B;  4AYR A;  1R33 A;  3EJR A;  1JZ6 A;  1KSD A;  2WW2 A;  2DRR A;  1W4N A;  1DP0 A;  3VD9 A;  4WVB A;  3QRY A;  1X9D A;  2WMF A;  2F7R A;  3Q1N A;  1N94 B;  4OK2 A;  4D6E A;  1N21 A;  1PS3 A;  4BZG A;  2WYI A;  3M73 A;  5JPN B;  3M77 A;  3E37 B;  1JZ5 A;  2JKA A;  4FXK B;  3DRA B;  3NBJ A;  1SA4 B;  2CIQ A;  3WKI A;  2CFG A;  4DUW A;  3SDT A;  1WU6 A;  3N0G A;  3HXD B;  4ZG8 A;  1NXC A;  1UI7 A;  2DRS A;  2W0Q A;  2BRP A;  4GTS B;  3IMH A;  1N4P B;  2WMI B;  3X3X A;  3MV1 1;  3T0D A;  1NL4 B;  4KTR A;  3BUP A;  1JYW A;  4Q2B A;  3WVF A;  3HIG A;  1O6H A;  1HXC A;  4AQ0 A;  1G6I A;  1HV6 A;  4ZH5 A;  1TN6 B;  2FUZ A;  1H13 A;  1TQS A;  3WA2 X;  2EAE A;  2OW7 A;  1H37 A;  1JZ2 A;  5ILD A;  3BUQ A;  3F59 A;  2OOV A;  3EJP A;  3M02 A;  3OB8 A;  2G02 A;  1O1S B;  3M75 A;  1W6K A;  3GZK A;  1RWA A;  3N9H A;  1WMP A;  2CG1 A;  3EU5 B;  2DRQ A;  3RX8 A;  1NS2 A;  3CIH A;  5GW7 A;  1LOH A;  4FJQ A;  3KLS A;  3KN4 A;  4AYQ A;  3QT3 A;  3TF4 A;  3K25 A;  3NJV A;  3DSU B;  5DHI A;  2A8Z A;  3ACS A;  3ECQ A;  3BLB A;  4GTM B;  1JZ7 A;  3BGA A;  3BUB A;  2WMJ A;  3PYB A;  4EV5 A;  2WYH A;  1RWG A;  3QFY A;  1TQW A;  5C05 A;  2GOX A;  1TQT A;  1V7V A;  2WMG A;  3UD1 A;  1D6Y A;  1JRQ A;  1MMU A;  3OS7 A;  1OAC A;  3T08 A;  1FP3 A;  4L6X A;  4RNQ A;  1AVK A;  3HI7 A;  3OXU A;  1HM2 A;  2D1W A;  4YDO B;  1C3D A;  3KBU C;  2XFG A;  1IA6 A;  3VXD A;  1NS8 A;  2RI8 A;  1RJO A;  4KTP A;  4C1S A;  3SFY B;  1NSZ A;  3RRS A;  2X03 A;  4CJ0 A;  2JKE A;  3PGB A;  4EV2 A;  2BT3 A;  1KFG A;  4K35 A;  1JOV A;  1X1J A;  2E2T A;  3KBT C;  2F7Q A;  2QNO A;  2CFD A;  1TN7 B;  4MU9 A;  4NEI A;  1KWF A;  1HXA A;  5IK6 A;  4YDE B;  4DUX A;  1A2V A;  3ON6 A;  3SDR A;  1F9G A;  4GTR B;  3AFJ A;  2WII B;  1AV4 A;  3QG0 A;  3SDU A;  3N0F A;  1S64 B;  1IVX A;  4FUS A;  1H3C A;  4D6D A;  3VD7 A;  2Z07 A;  1N7P A;  1OJP A;  2VN7 A;  1QQF A;  1GAI A;  2YX9 A;  5FO9 B;  2ZIS B;  4KFD A;  4KFF A;  5IK9 A;  5FOB B;  1GXO A;  2ALW A;  4F13 A;  1O5M B;  2H6H B;  1AGM A;  2HTB A;  1TNB B;  1H54 A;  3MWX A;  4FXG B;  3S4D A;  3M71 A;  1V5D A;  1X1I A;  2Q1F A;  2B4F A;  1PU4 A;  3VDC A;  2ONG A;  1Z45 A;  2WYN A;  4TTG A;  1TQU A;  1JZ3 A;  1LF6 A;  1FPP B;  3U7V A;  1NSV A;  5M7I A;  3D5R A;  3M78 A;  1PX4 A;  4Z4L A;  3RSY A;  3D50 A;  2JG0 A;  1I8Q A;  3G6J B;  3GT5 A;  2FV0 A;  1NSU A;  1GXM A;  2CWU A;  2BED B;  2WVZ A;  3QDE A;  1FAE A;  3Q79 B;  2NVP A;  1D6U A;  1HWW A;  3S4C A;  1NS0 A;  1N95 B;  2OOV C;  2ZXQ A;  2CQS A;  2WMH A;  1IVW A;  1NS4 A;  1KSI A;  3X42 A;  1RKY A;  3VD4 A;  3PQI A;  1QAL A;  3M00 A;  3EJU A;  1NC5 A;  3H3K A;  1DYU A;  4D4B A;  1RWC A;  1NSS A;  1H3A A;  2KXS A;  4ZRQ A;  3E7J A;  2CG0 A;  3SXX A;  2ZBL A;  4FNP A;  4BOJ A;  3BUD A;  2OQE C;  4LNV A;  1RWF A;  3S4A A;  4Q88 A;  4BZH A;  2BRV X;  1TXK A;  1ULV A;  1EGU A;  5ILI A;  5ILZ A;  2E2U A;  3MUZ 1;  3CZS A;  1R34 A;  2V8K A;  1K72 A;  1YGA A;  5ILH A;  1QSJ A;  3SX1 A;  4OZW A;  3PMM A;  1JCR B;  4GTQ B;  5EAS A;  5EAU A;  3ALA A;  4ZRP A;  1TNZ B;  1O6R A;  1QAF A;  3K11 A;  5EAT A;  3RJ3 A;  2R2L B;  2GZ6 A;  3Q78 B;  3WC3 A;  3Q7F B;  1KS8 A;  1N1B A;  4AYO A;  1H3B A;  1N22 A;  1RQ5 A;  3DX4 A;  2A73 B;  1QBQ B;  3M01 A;  1X81 B;  1L7K A;  2BRW A;  3C72 B;  4JJJ A;  1TN8 B;  3DYM A;  1W5Z A;  3E1F 1;  3DSS B;  3NRE A;  1J0N A;  1SII A;  3WFA A;  4CE7 A;  1HX9 A;  3WIQ A;  3HXE B;  4V1S A;  3T09 A;  4D72 A;  2F1A A;  1FO2 A;  1JS4 A;  5IKH A;  3G4D A;  3X17 A;  1RW9 A;  2WGQ A;  3KII A;  4EHM B;  2ZL8 A;  5JMD A;  4RNL A;  2JF4 A;  5AGD A;  3PZ4 B;  3T33 A;  3WUX A;  2C10 A;  2BB5 A;  5JMF A;  1MMY A;  4MMH A;  3EUV B;  1JCQ B;  4DOE A;  3E34 B;  3SDQ A;  3E6U A;  2OQE A;  2WO0 A;  1DL2 A;  1QAZ A;  1N4Q B;  2WY7 A;  2WMI A;  2ZZR A;  1LXK A;  5E2J A;  3WIW A;  1UI8 A;  1V7X A;  3KSL B;  3KQ4 A;  3BVV A;  1HCU A;  1GSZ A;  4DI5 A;  1FO3 A;  3BUI A;  1H35 A;  3X3Z A;  4MMI A;  1HXG A;  1KRF A;  2CQT A;  2AHF A;  2HTA A;  3CZN A;  1FBO A;  3VW5 A;  2P0V A;  4WVC A;  1L7J A;  3OED A;  3X3Y A;  3DSV B;  4KKI A;  2XHN A;  3DCD A;  1HN0 A;  5ILJ A;  1KZP B;  3WA3 A;  1TQV A;  2WOH A;  2CWT A;  3EJQ A;  4BZE A;  2D5J A;  5CZL A;  2WMK A;  1DCE B;  1SPU A;  3D51 A;  2CFW A;  4K3A A;  3W5M A;  4LIX A;  3EU8 A;  1W6G A;  4XUV A;  3BS6 A;  1D6Z A;  1LF9 A;  4OJZ A;  3S9V A;  2WY8 A;  4D8O A;  1O6Q A;  3S4B A;  1D8E B;  3A24 A;  2WVX B;  5A1A A;  2CFL A;  3EJS A;  4D94 A;  3IAQ A;  3SQC A;  4BTY A;  4J5T A;  4ZH1 A;  1TNU B;  5CA3 A;  1NS7 A;  3BLC A;  3I3B A;  3HXC B;  3DST B;  3NNB A;  3BVU A;  3RX5 A;  1H14 A;  1QX1 A;  3NJX A;  2WZS A;  1G9J A;  1TF4 A;  1GA2 A;  3SDV A;  5ILK A;  3W7S A;  2F0Y B;  3AMO B;  1L2A A; 
#chains in the Genus database with same CATH homology
 1MN0 A;  3WVF A;  3E7J A;  1HMW A;  3T2P A;  1MMZ A;  1HV6 A;  1OJM A;  4AQ0 A;  4FNV A;  1CB8 A;  4D6I A;  1NSX A;  2WW3 A;  3OB8 A;  3SEP A;  1RWF A;  3E80 A;  2XSG A;  4BZH A;  1SNZ A;  2BRV X;  4F10 A;  1TXK A;  1EGU A;  1ULV A;  3MUZ 1;  2WVX A;  1NKG A;  3T2O A;  1RWA A;  3I3E A;  1YGA A;  1NS2 A;  1HMU A;  1J0M A;  1LOH A;  3TY1 A;  4OZW A;  2ZQ0 A;  3K25 A;  3NJV A;  1K1Y A;  3VD9 A;  1HM3 A;  1N7O A;  4E1Y A;  3DYO A;  3ECQ A;  3VSN A;  5E1Q A;  2E24 A;  4D6G A;  1JYV A;  1JZ7 A;  3MUY 1;  3BGA A;  2WMJ A;  1N7R A;  1RWG A;  1L7K A;  2BRW A;  2E22 A;  1NSM A;  1MMY A;  2WMG A;  3DYM A;  1MMU A;  2FUQ A;  4D6C A;  3E1F 1;  1J0N A;  3NRE A;  3OS7 A;  2D73 A;  3T0B A;  4D6J A;  3WFA A;  1PX3 A;  3VSM A;  3I3D A;  3T0A A;  2FUT A;  3T09 A;  3T08 A;  1RWH A;  3T2Q A;  4DUV A;  4D72 A;  1HM2 A;  1JZ2 A;  1RW9 A;  1HN1 A;  1NS8 A;  5JMD A;  4RNL A;  3VD3 A;  1LUR A;  3VDB A;  1JZ8 A;  1JZ4 A;  1NSZ A;  3MV0 1;  2X03 A;  5JMF A;  2JKE A;  1F1S A;  1W3Y A;  4MMH A;  1UG9 A;  1C82 A;  3CZJ A;  1K1X A;  1JOV A;  1X1J A;  3NFV A;  1QAZ A;  4OZV A;  2WMI A;  1YQ2 A;  3VD5 A;  1LXK A;  1SO0 A;  4NEI A;  2WCO A;  4DUX A;  1F9G A;  4MMI A;  1LXM A;  2CIR A;  2WW0 A;  3AFL A;  2HTA A;  4D6D A;  1L7J A;  1F4A A;  3VD7 A;  1N7P A;  1OJP A;  2XHN A;  3DCD A;  1HN0 A;  1N7Q A;  3J7H A;  1OJO A;  2WDA A;  1JYN A;  4OK4 A;  3A0O A;  4BZE A;  1NSR A;  2WMK A;  3DEC A;  4D6F A;  4F13 A;  1JZ6 A;  1X1H A;  2HTB A;  1MMX A;  2WW2 A;  3MWX A;  3BS6 A;  1DP0 A;  2WVY A;  3DYP A;  1LF9 A;  2WMF A;  1X1I A;  2Q1F A;  4OJZ A;  4D71 A;  1K1W A;  1F4H A;  4OK2 A;  3Q1N A;  4D6E A;  4BZG A;  3VDC A;  1Z45 A;  4TTG A;  3A24 A;  2WVX B;  4BZF A;  5A1A A;  1JZ3 A;  1LF6 A;  3IAQ A;  1NSV A;  2CIS A;  1JZ5 A;  2JKA A;  1PX4 A;  4D6H A;  1I8Q A;  4J5T A;  2CIQ A;  1NS7 A;  1NSU A;  2JKP A;  2WVZ A;  3BLC A;  3I3B A;  1JYX A;  3IAP A;  4DUW A;  3NNB A;  1NS0 A;  2ZXQ A;  2WMH A;  1NS4 A;  1N7N A;  3VD4 A;  3NJX A;  2BRP A;  2WW1 A;  2WZS A;  3IMH A;  2WMI B;  3VDA A;  3MV1 1;  1OJN A;  3T0D A;  3OBA A;  1JYW A;  1RWC A;  1NSS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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