1W3YA

Crystal structure of s. pneumoniae hyaluronate lyase in complex with palmitoyl-vitamin c
Total Genus 254
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
721
structure length
721
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title L-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor: X-Ray Structure and Molecular Modeling of Enzyme-Inhibitor Complexes
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 254
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2004-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1w3yA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1w3yA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1w3yA01
1PX4A 2WW2A 4DUVA 1RWFA 2E22A 4AQ0A 3Q1NA 3T0AA 1J0NA 1LXKA 3IAPA 1DP0A 1RW9A 1HMWA 1NS0A 1HM2A 1JYNA 1F9GA 4DUWA 3VD9A 1JYXA 4MMHA 2WVXB 3VDBA 1RWGA 2HTBA 4NEIA 1N7NA 2JKPA 1PX3A 4BZHA 4OJZA 4D71A 4E1YA 2WMIA 1JZ4A 3MV01 1NSRA 3T09A 1HN1A 4OZWA 4D72A 3VD5A 3A24A 1JYVA 1J0MA 1NS8A 2BRWA 1X1JA 3NREA 1ULVA 5JMFA 2BRVX 3DECA 4DUXA 1LF6A 3E1F1 5JMDA 4D6GA 1MMUA 4TTGA 2E24A 4D6EA 3A0OA 2WMKA 3I3EA 3VDCA 4BZFA 1SO0A 1NSMA 2WMGA 4MMIA 4F13A 1LURA 2D73A 2X03A 3OBAA 1QAZA 1K1YA 3NJVA 3T0DA 1K1XA 2WVZA 2XHNA 5E1QA 3DYMA 3J7HA 1NS4A 2WW1A 1LOHA 3AFLA 1OJPA 3DCDA 3I3BA 1LXMA 2WZSA 1JZ5A 3T2PA 1HM3A 1HN0A 3SEPA 2WVXA 4OZVA 1YQ2A 1NSSA 2HTAA 1SNZA 1N7PA 4BZEA 4RNLA 1F1SA 1I8QA 2WMJA 3IMHA 3DYOA 1OJOA 1NSXA 2WDAA 4D6DA 4BZGA 3MUZ1 2FUQA 2WCOA 1N7OA 1JZ6A 3MWXA 3E7JA 4FNVA 1JYWA 2FUTA 3VD7A 3T0BA 3NFVA 3WFAA 1JOVA 1L7JA 1MN0A 1MMYA 1LF9A 2CISA 3VSNA 2JKEA 1F4AA 1RWAA 1YGAA 1F4HA 2CIRA 2ZXQA 1C82A 2WMHA 3NNBA 4OK2A 1JZ8A 4OK4A 1X1HA 1UG9A 1RWHA 3DYPA 1JZ3A 3T08A 3T2QA 2ZQ0A 1N7RA 1Z45A 1L7KA 1RWCA 3NJXA 1TXKA 3I3DA 2CIQA 1JZ2A 3MV11 4D6JA 1NSVA 2BRPA 2WMIB 1OJNA 4F10A 2XSGA 3CZJA 1K1WA 4D6IA 1N7QA 1NS2A 3ECQA 3VSMA 1EGUA 1CB8A 1NS7A 1JZ7A 3IAQA 3VDAA 3BGAA 3K25A 3MUY1 4D6HA 1MMXA 2WW0A 3VD3A 2WVYA 1HV6A 3OS7A 3OB8A 1W3YA 1OJMA 1NSUA 3T2OA 5A1AA 2JKAA 1X1IA 2WMFA 1NKGA 3VD4A 1MMZA 1HMUA 4D6FA 4D6CA 2WW3A 1NSZA 3E80A 2Q1FA
chains in the Genus database with same CATH superfamily
1N95B 1KSIA 1FMIA 4KTRA 3IAPA 2CQSA 1HXGA 3KSLB 1RW9A 3WKIA 4JJJA 3RX7A 4GL3A 1D8DB 3EUVB 1V5DA 3SAEA 3X17A 1R76A 1H3CA 3ANKA 2Y74A 2RDYA 2HTBA 1PX3A 3M00A 1QAKA 4LNBB 3HXEB 4CE7A 3X3YA 3GT5A 2OOVA 4BTYA 3MV01 3T09A 2J5CA 1WU6A 1J0MA 4ZH1A 3KN4A 4DOEA 1X1JA 4GAXA 1N4RB 3DECA 2XN2A 3E1F1 4LIXA 1MMUA 1KKTA 4D1JA 4AYPA 4D6EA 2WMKA 2XN1A 2CG0A 3VDCA 3LOYA 4WVCA 1WU4A 2DRSA 3E73A 2WMGA 2WIIB 3D4YA 4GTVB 3X3XA 2ZZRA 3OBAA 1C3DA 3WIRA 1H54A 2A8ZA 3KIIA 1NC5A 1XWQA 5JPMB 3T0DA 3U7VA 1K1XA 2WVZA 3HIIA 1G6IA 1G87A 3G6JB 1LD7B 3M77A 5IK6A 2NOJA 3G4FA 1NS4A 3X42A 3ANJA 3AFLA 4AYRA 2CFWA 1TNYB 1JZ5A 1O79A 3N9HA 1SIIA 2F7PA 1YQ2A 3KLSA 2HTAA 4BZEA 2WGQA 1W6KA 1N22A 3D4ZA 4RNLA 1DYUA 1D8EB 2B39A 2I07B 5GZKA 2F7OA 1FP3A 3MUZ1 2FUQA 5JPNB 4MU9A 1DCEB 3S4AA 3DSSB 3S4CA 2H6HB 2E2TA 1JOVA 3CZSA 1MMYA 2CISA 1GXOA 1HCUA 5ILZA 4KKJA 2ZISB 3SDQA 2JKEA 4DODA 3EJRA 2GOXA 3M7BA 2WMHA 4GTMB 3NNBA 1JZ8A 1SPUA 3GZKA 4OK4A 2F1BA 2F18A 1RWHA 1LD8B 2VN7A 5DGQA 2ZQ0A 1N7RA 1L7KA 4ZG8A 1AV4A 2GH4A 5EATA 5ILKA 4K3AA 2E2UA 3MV11 3EJUA 1FCEA 3QRYA 1NL4B 3QT9A 4GTPB 2BRPA 3VXDA 1PS3A 2WMIB 3AMOB 4F10A 1K1WA 4D6IA 1TQWA 5DHIA 3F59A 1JCQB 1FT1B 1A2VA 3A3VA 1KWFA 2OW7A 1QSJA 2F7RA 3HXCB 3EU5B 3IAQA 3BGAA 3N0FA 3T33A 2KXSA 1GXNA 4D6HA 1TQTA 2CFKA 2WW0A 3M02A 4J5TA 2W0QA 1R33A 1KREA 3WKGA 3T2OA 2YX9A 2ZL8A 5A1AA 5ILIA 2OQEA 2WYIA 4D94A 1NKGA 3VD4A 1H14A 4D6FA 4KTPA 3E6UA 3M73A 3QFZA 5ILHA 4FXKB 2WW2A 3EZ8A 4FNPA 3WVFA 1QAFA 4CJ0A 5FO7B 4Q88A 1F9GA 3MPHA 1UI8A 3RENA 4YDEB 1X9DA 1TF4A 4TXTA 2JJBA 2EAEA 3W7TA 4NEIA 1TQVA 1CLCA 2JKPA 1TNBB 2WMIA 3AMOA 2GZ6A 3D5RA 2RGKA 1R34A 3EJSA 4KFEA 4D72A 1QWNA 2NVPA 3VD5A 2BRWA 3NREA 1ULVA 5JMFA 2BRVX 3AFJA 1AVLA 3QG0A 3QFYA 5KBPA 3EU8A 5JMDA 2WO0A 3BLCA 4TTGA 1JRQA 3HXDB 1SO0A 3E37B 1SIHA 1QQFA 3E30B 3PZ1B 1LVNA 4EV2A 1KZPB 4F13A 4V1RA 4YDOB 3QDEA 2QNOA 3UD2A 5FO9B 3WIQA 2BBCA 4KFFA 2FUZA 3P2CA 3KBTC 2FV0A 4ONTA 4WU0A 5E1QA 3DYMA 3J7HA 3ALAA 3DX0A 2G0DA 1TNOB 1FBOA 2FYVA 3Q7AB 2WW1A 3BVWA 1TN6B 2XWBB 1HXKA 2YFNA 3DCDA 3PGBA 2H6IB 2WZSA 3T2PA 3KBUC 1HN0A 1TNZB 1FT2B 4OZVA 1XW2A 1IA7A 1NSSA 1N7PA 3UD1A 3HI7A 1QX1A 1H37A 5DGRA 3RX5A 4BOJA 1OJOA 1F9DA 1N1BA 2IEJB 3Q7FB 3PQIA 3PZ3B 1NSXA 1JCSB 2WCOA 1N7OA 1JZ6A 2CWUA 3MWXA 3PMMA 1JYWA 1UT9A 2FUTA 1K72A 3DSUB 2CWTA 3VD7A 2WYHA 3WA2X 3RX8A 1L7JA 2Z07A 3TY1A 1LF9A 4TF4A 1IQXA 3DSVB 5ILYA 2XWJB 2ZXQA 1RKYA 1C82A 1GHQA 1EKMA 5DHKA 1TQSA 3WUXA 1KFGA 3H7LA 3DYPA 1JZ3A 3T2QA 4FUSA 1Z45A 1RWCA 3D5SA 1FAEA 3NJXA 1TXKA 3I3DA 1JZ2A 3CU7A 3NBJA 1KSCA 3KSQB 1HXAA 3DX4A 3BS6A 2C10A 4BTWA 5CA3A 3CZJA 3EJPA 3BVVA 1SA5B 3LVTA 2ZBLA 3DX3A 3ECQA 3VSMA 1NS7A 1CB8A 3SFYB 1HTYA 5IK9A 1IVVA 1N9AB 3SFXB 3OXUA 3WIWA 3W5NA 3K25A 1JZ7A 2DROA 4DLQA 4V1SA 2ALWA 3VD3A 1VD5A 1WU5A 3OS7A 1HXCA 5FO8B 2CWVA 4EL8A 3OEDA 1W3YA 5AGDA 1NSUA 2JKAA 1X1IA 4D8OA 3Q79B 1MMZA 3M7CA 5M7IA 1CEMA 2RI8A 2Q1FA 4Z4JA 4DUVA 1N94B 1RWFA 3W7SA 4AQ0A 3Q1NA 3S4DA 1FPPB 1J0NA 1NI1B 2BEDB 3CIHA 3K11A 1PU4A 3RRSA 1L1YA 2H6FB 1HM2A 3DDFA 1JYNA 3M71A 3VD9A 1O5MB 2XN0A 1JYXA 1DL2A 3PZ2B 4MMHA 2WVXB 3DX1A 4FNTA 3M01A 1KS8A 1N7NA 4BZHA 4OJZA 3ON6A 1NXCA 4D71A 4E1YA 2F6DA 2RI9A 1KZOB 1H36A 1V7VA 4OZWA 1HN1A 1JYVA 3BUPA 4L6XA 1NS8A 2KXRA 2A73B 5M7YA 4DUXA 2XFGA 1LF6A 1UMPA 2SQCA 4RNQA 4EHMB 1S64B 3SDRA 2C11A 3BLBA 4LNGB 1TN8B 2PN5A 3TF4A 2E24A 3A0OA 4BZFA 5IKAA 3PZ4B 1X81B 4Z4LA 2AHGA 2B4FA 2BB5A 3SXXA 2V8KA 3W7XA 4MMIA 5IK0A 3SX1A 1FBWA 2D73A 4FNUA 3G4DA 3T0UA 2YIKA 3ACTA 1QAZA 3NJVA 4GTSB 4FNQA 4D4BA 1N4SB 3BUQA 2XHNA 3W5MA 3M74A 1HWWA 2ZIRB 1LXMA 3D52A 5CZLA 3M78A 5IL3A 3SEPA 2WVXA 1TQUA 1H3BA 1SNZA 3Q73B 1F1SA 5IKHA 2WMJA 4QT9A 4WVBA 3WC3A 3KQ4A 2V3NA 3S4BA 4D1IA 3DYOA 1O1SB 2R2LB 4D6DA 4KFDA 4BZGA 4BTXA 4DI5A 3GLYA 1IA6A 3E7JA 4FNVA 2JG0A 2VN4A 3T0BA 1FO3A 3W7UA 1MN0A 1IU7A 3E32B 3VSNA 1N20A 1OACA 2ONHA 3M76A 3WKFA 1RWAA 2AFAA 4D4DA 2FBAA 1L2AA 1F4HA 1YGAA 4Q2BA 2CIRA 3QXQA 1D6UA 3BUBA 4OK2A 2D5JA 3P5PA 2WYNA 1UI7A 1QBQB 3PYBA 4GTRB 5FOBB 1N24A 1GXMA 4BOKA 1W5ZA 1N21A 2JF4A 1WMOA 4K35A 4CJ1A 3HXBB 4YCRA 1NSVA 3X3ZA 2EADA 2WOHA 1FO2A 1HZFA 1O6QA 1N9EA 1TN7B 1OJNA 4ZH5A 1V5CA 1QWUA 2XSGA 2XQWA 3N0GA 1N7QA 4FNRA 2WY7A 1IQYA 3QT3A 4MBGB 3H3KA 3QPFA 1O6HA 3QSPA 1HX9A 2F7QA 4DLOA 1W7CA 3VDAA 4EV5A 1MMXA 3SQCA 3Q78B 2AHFA 1DOGA 3QXFA 2YFOA 1O7DD 2CFGA 2F1AA 3Q75B 1OJMA 3WA3A 1N1ZA 2WMFA 3E34B 1S63B 5EAUA 1JCRB 3PYAA 2PMVA 3NBBA 4GTQB 3DSTB 3DSWB 3E80A 3QR8A 1PX4A 1GAIA 1W6JA 2E22A 3ANIA 5ILJA 3CZNA 3T0AA 3C72B 3BUDA 1LXKA 2Y73A 1F9OA 1DP0A 1GLMA 1HMWA 1JS4A 1NS0A 4DUWA 4L0GA 5IL8A 1W6GA 3BVUA 3VDBA 1RWGA 4M76A 3SDUA 2OOVC 3DDGA 1TNUB 1GAHA 1RJOA 3DSXB 3K7XA 3HIGA 5EASA 4GTOB 1H39A 2E2VA 3BVTA 1JZ4A 1TU5A 1V7XA 2BB6A 4LNVA 1NSRA 3K5TA 2PNCA 3A24A 3E33B 5E2JA 3LZ9A 5IM1A 4GTTB 3D3IA 3SDTA 3CV5A 1O1TB 3M75A 3HXFB 4D6GA 1N4QB 4KKIA 1O1RB 1RQ5A 2DRQA 1IVWA 3I3EA 1GA2A 3EQAA 3WKHA 1WMPA 3VW5A 2CG1A 1NSMA 2WOFA 3QWTA 3SDVA 1H35A 4AYOA 4ZRQA 1SA4B 2D1WA 1LURA 2H6GB 2X03A 3DPYB 1N4PB 1K1YA 5MEHA 3DX2A 4C1SA 2BT3A 2EACA 1MZCB 1QALA 4FJQA 1H12A 1LTXB 1V7WA 1LOHA 2F0YB 2ONGA 1OJPA 3X40A 3I3BA 1O6RA 4D4AA 3MI6A 1XWTA 1HM3A 1AYXA 1IVXA 1WMNA 1W4NA 1I8QA 1KRFA 3IMHA 2P0VA 2WDAA 3M72A 5CD2A 4FXGB 5GW7A 4WVAA 1AVKA 1IS9A 1US1A 2G02A 3WFAA 3NFVA 5ILDA 3EJTA 5KKBA 2V3PA 2OW6A 1G9GA 2DRRA 3M7LA 1F4AA 3ACSA 1W2ZA 1H13A 1G9JA 3M7EA 1D6ZA 3D50A 1H3AA 3W7WA 2CQTA 3P5RA 1UG9A 1X1HA 3EJQA 3T08A 5C05A 2V8JA 3RSYA 2WINB 3X41A 2CIQA 3S9VA 3BUIA 1W6CA 4D6JA 4D4CA 3H2WA 1GSZA 4ZRPA 1KSDA 1SQCA 2CFDA 4L9PB 1NS2A 2V8IA 1EGUA 4UFCA 2EABA 3RJ3A 3MUY1 1AGMA 5GY3A 4AYQA 2FV1A 1IVUA 2OQEC 2WVYA 3D51A 1HV6A 1N23A 3DRAB 2D8LA 2OKXA 3OB8A 2WY8A 4FNSA 1D6YA 1WZZA 4XUVA 3BVXA 1HMUA 2CFLA 4D6CA 2WW3A 1NSZA
chains in the Genus database with same CATH topology
1PX4A 2WW2A 4DUVA 1RWFA 2E22A 4AQ0A 3Q1NA 3T0AA 1J0NA 1LXKA 3IAPA 3WVFA 1DP0A 1RW9A 1HMWA 1NS0A 1HM2A 1JYNA 1F9GA 4DUWA 3VD9A 1JYXA 4MMHA 2WVXB 3VDBA 1RWGA 2HTBA 4NEIA 1N7NA 2JKPA 1PX3A 4BZHA 4OJZA 4D71A 4E1YA 2WMIA 1JZ4A 3MV01 1NSRA 3T09A 1HN1A 4OZWA 4D72A 3VD5A 3A24A 1JYVA 1J0MA 1NS8A 2BRWA 1X1JA 3NREA 1ULVA 5JMFA 2BRVX 3DECA 4DUXA 1LF6A 3E1F1 5JMDA 4D6GA 1MMUA 3BLCA 4TTGA 2E24A 4D6EA 3A0OA 2WMKA 3I3EA 3VDCA 4BZFA 1SO0A 1NSMA 2WMGA 4MMIA 4F13A 1LURA 2D73A 2X03A 3OBAA 1QAZA 1K1YA 3NJVA 3T0DA 1K1XA 2WVZA 2XHNA 5E1QA 3DYMA 3J7HA 1NS4A 2WW1A 1LOHA 3AFLA 1OJPA 3DCDA 3I3BA 1LXMA 2WZSA 1JZ5A 3T2PA 1HM3A 1HN0A 3SEPA 2WVXA 4OZVA 1YQ2A 1NSSA 2HTAA 1SNZA 1N7PA 4BZEA 4RNLA 1F1SA 1I8QA 2WMJA 3IMHA 3DYOA 1OJOA 1NSXA 2WDAA 4D6DA 4BZGA 3MUZ1 2FUQA 2WCOA 1N7OA 1JZ6A 3MWXA 3E7JA 4FNVA 1JYWA 2FUTA 3VD7A 3T0BA 3NFVA 3WFAA 1JOVA 1L7JA 1MN0A 1MMYA 3TY1A 1LF9A 2CISA 3VSNA 2JKEA 1F4AA 1RWAA 1YGAA 1F4HA 2CIRA 2ZXQA 1C82A 2WMHA 3NNBA 4OK2A 1JZ8A 4OK4A 1X1HA 1UG9A 1RWHA 3DYPA 1JZ3A 3T08A 3T2QA 2ZQ0A 1N7RA 1Z45A 1L7KA 1RWCA 3NJXA 1TXKA 3I3DA 2CIQA 1JZ2A 3MV11 4D6JA 1NSVA 2BRPA 3BS6A 2WMIB 1OJNA 4F10A 2XSGA 3CZJA 1K1WA 4D6IA 1N7QA 1NS2A 3ECQA 3VSMA 1EGUA 1CB8A 1NS7A 1JZ7A 3IAQA 3VDAA 3BGAA 3K25A 3MUY1 4D6HA 1MMXA 2WW0A 3VD3A 4J5TA 2WVYA 1HV6A 3OS7A 3OB8A 1W3YA 1OJMA 1NSUA 3T2OA 5A1AA 2JKAA 1X1IA 2WMFA 1NKGA 3VD4A 1MMZA 1HMUA 4D6FA 4D6CA 2WW3A 1NSZA 3E80A 2Q1FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PX4 A;  2WW2 A;  4DUV A;  1RWF A;  2E22 A;  4AQ0 A;  3Q1N A;  3T0A A;  1J0N A;  1LXK A;  3IAP A;  1DP0 A;  1RW9 A;  1HMW A;  1NS0 A;  1HM2 A;  1JYN A;  1F9G A;  4DUW A;  3VD9 A;  1JYX A;  4MMH A;  2WVX B;  3VDB A;  1RWG A;  2HTB A;  4NEI A;  1N7N A;  2JKP A;  1PX3 A;  4BZH A;  4OJZ A;  4D71 A;  4E1Y A;  2WMI A;  1JZ4 A;  3MV0 1;  1NSR A;  3T09 A;  1HN1 A;  4OZW A;  4D72 A;  3VD5 A;  3A24 A;  1JYV A;  1J0M A;  1NS8 A;  2BRW A;  1X1J A;  3NRE A;  1ULV A;  5JMF A;  2BRV X;  3DEC A;  4DUX A;  1LF6 A;  3E1F 1;  5JMD A;  4D6G A;  1MMU A;  4TTG A;  2E24 A;  4D6E A;  3A0O A;  2WMK A;  3I3E A;  3VDC A;  4BZF A;  1SO0 A;  1NSM A;  2WMG A;  4MMI A;  4F13 A;  1LUR A;  2D73 A;  2X03 A;  3OBA A;  1QAZ A;  1K1Y A;  3NJV A;  3T0D A;  1K1X A;  2WVZ A;  2XHN A;  5E1Q A;  3DYM A;  3J7H A;  1NS4 A;  2WW1 A;  1LOH A;  3AFL A;  1OJP A;  3DCD A;  3I3B A;  1LXM A;  2WZS A;  1JZ5 A;  3T2P A;  1HM3 A;  1HN0 A;  3SEP A;  2WVX A;  4OZV A;  1YQ2 A;  1NSS A;  2HTA A;  1SNZ A;  1N7P A;  4BZE A;  4RNL A;  1F1S A;  1I8Q A;  2WMJ A;  3IMH A;  3DYO A;  1OJO A;  1NSX A;  2WDA A;  4D6D A;  4BZG A;  3MUZ 1;  2FUQ A;  2WCO A;  1N7O A;  1JZ6 A;  3MWX A;  3E7J A;  4FNV A;  1JYW A;  2FUT A;  3VD7 A;  3T0B A;  3NFV A;  3WFA A;  1JOV A;  1L7J A;  1MN0 A;  1MMY A;  1LF9 A;  2CIS A;  3VSN A;  2JKE A;  1F4A A;  1RWA A;  1YGA A;  1F4H A;  2CIR A;  2ZXQ A;  1C82 A;  2WMH A;  3NNB A;  4OK2 A;  1JZ8 A;  4OK4 A;  1X1H A;  1UG9 A;  1RWH A;  3DYP A;  1JZ3 A;  3T08 A;  3T2Q A;  2ZQ0 A;  1N7R A;  1Z45 A;  1L7K A;  1RWC A;  3NJX A;  1TXK A;  3I3D A;  2CIQ A;  1JZ2 A;  3MV1 1;  4D6J A;  1NSV A;  2BRP A;  2WMI B;  1OJN A;  4F10 A;  2XSG A;  3CZJ A;  1K1W A;  4D6I A;  1N7Q A;  1NS2 A;  3ECQ A;  3VSM A;  1EGU A;  1CB8 A;  1NS7 A;  1JZ7 A;  3IAQ A;  3VDA A;  3BGA A;  3K25 A;  3MUY 1;  4D6H A;  1MMX A;  2WW0 A;  3VD3 A;  2WVY A;  1HV6 A;  3OS7 A;  3OB8 A;  1W3Y A;  1OJM A;  1NSU A;  3T2O A;  5A1A A;  2JKA A;  1X1I A;  2WMF A;  1NKG A;  3VD4 A;  1MMZ A;  1HMU A;  4D6F A;  4D6C A;  2WW3 A;  1NSZ A;  3E80 A;  2Q1F A; 
#chains in the Genus database with same CATH topology
 1N95 B;  1KSI A;  1FMI A;  4KTR A;  3IAP A;  2CQS A;  1HXG A;  3KSL B;  1RW9 A;  3WKI A;  4JJJ A;  3RX7 A;  4GL3 A;  1D8D B;  3EUV B;  1V5D A;  3SAE A;  3X17 A;  1R76 A;  1H3C A;  3ANK A;  2Y74 A;  2RDY A;  2HTB A;  1PX3 A;  3M00 A;  1QAK A;  4LNB B;  3HXE B;  4CE7 A;  3X3Y A;  3GT5 A;  2OOV A;  4BTY A;  3MV0 1;  3T09 A;  2J5C A;  1WU6 A;  1J0M A;  4ZH1 A;  3KN4 A;  4DOE A;  1X1J A;  4GAX A;  1N4R B;  3DEC A;  2XN2 A;  3E1F 1;  4LIX A;  1MMU A;  1KKT A;  4D1J A;  4AYP A;  4D6E A;  2WMK A;  2XN1 A;  2CG0 A;  3VDC A;  3LOY A;  4WVC A;  1WU4 A;  2DRS A;  3E73 A;  2WMG A;  2WII B;  3D4Y A;  4GTV B;  3X3X A;  2ZZR A;  3OBA A;  1C3D A;  3WIR A;  1H54 A;  2A8Z A;  3KII A;  1NC5 A;  1XWQ A;  5JPM B;  3T0D A;  3U7V A;  1K1X A;  2WVZ A;  3HII A;  1G6I A;  1G87 A;  3G6J B;  1LD7 B;  3M77 A;  5IK6 A;  2NOJ A;  3G4F A;  1NS4 A;  3X42 A;  3ANJ A;  3AFL A;  4AYR A;  2CFW A;  1TNY B;  1JZ5 A;  1O79 A;  3N9H A;  1SII A;  2F7P A;  1YQ2 A;  3KLS A;  2HTA A;  4BZE A;  2WGQ A;  1W6K A;  1N22 A;  3D4Z A;  4RNL A;  1DYU A;  1D8E B;  2B39 A;  2I07 B;  5GZK A;  2F7O A;  1FP3 A;  3MUZ 1;  2FUQ A;  5JPN B;  4MU9 A;  1DCE B;  3S4A A;  3DSS B;  3S4C A;  2H6H B;  2E2T A;  1JOV A;  3CZS A;  1MMY A;  2CIS A;  1GXO A;  1HCU A;  5ILZ A;  4KKJ A;  2ZIS B;  3SDQ A;  2JKE A;  4DOD A;  3EJR A;  2GOX A;  3M7B A;  2WMH A;  4GTM B;  3NNB A;  1JZ8 A;  1SPU A;  3GZK A;  4OK4 A;  2F1B A;  2F18 A;  1RWH A;  1LD8 B;  2VN7 A;  5DGQ A;  2ZQ0 A;  1N7R A;  1L7K A;  4ZG8 A;  1AV4 A;  2GH4 A;  5EAT A;  5ILK A;  4K3A A;  2E2U A;  3MV1 1;  3EJU A;  1FCE A;  3QRY A;  1NL4 B;  3QT9 A;  4GTP B;  2BRP A;  3VXD A;  1PS3 A;  2WMI B;  3AMO B;  4F10 A;  1K1W A;  4D6I A;  1TQW A;  5DHI A;  3F59 A;  1JCQ B;  1FT1 B;  1A2V A;  3A3V A;  1KWF A;  2OW7 A;  1QSJ A;  2F7R A;  3HXC B;  3EU5 B;  3IAQ A;  3BGA A;  3N0F A;  3T33 A;  2KXS A;  1GXN A;  4D6H A;  1TQT A;  2CFK A;  2WW0 A;  3M02 A;  4J5T A;  2W0Q A;  1R33 A;  1KRE A;  3WKG A;  3T2O A;  2YX9 A;  2ZL8 A;  5A1A A;  5ILI A;  2OQE A;  2WYI A;  4D94 A;  1NKG A;  3VD4 A;  1H14 A;  4D6F A;  4KTP A;  3E6U A;  3M73 A;  3QFZ A;  5ILH A;  4FXK B;  2WW2 A;  3EZ8 A;  4FNP A;  3WVF A;  1QAF A;  4CJ0 A;  5FO7 B;  4Q88 A;  1F9G A;  3MPH A;  1UI8 A;  3REN A;  4YDE B;  1X9D A;  1TF4 A;  4TXT A;  2JJB A;  2EAE A;  3W7T A;  4NEI A;  1TQV A;  1CLC A;  2JKP A;  1TNB B;  2WMI A;  3AMO A;  2GZ6 A;  3D5R A;  2RGK A;  1R34 A;  3EJS A;  4KFE A;  4D72 A;  1QWN A;  2NVP A;  3VD5 A;  2BRW A;  3NRE A;  1ULV A;  5JMF A;  2BRV X;  3AFJ A;  1AVL A;  3QG0 A;  3QFY A;  5KBP A;  3EU8 A;  5JMD A;  2WO0 A;  3BLC A;  4TTG A;  1JRQ A;  3HXD B;  1SO0 A;  3E37 B;  1SIH A;  1QQF A;  3E30 B;  3PZ1 B;  1LVN A;  4EV2 A;  1KZP B;  4F13 A;  4V1R A;  4YDO B;  3QDE A;  2QNO A;  3UD2 A;  5FO9 B;  3WIQ A;  2BBC A;  4KFF A;  2FUZ A;  3P2C A;  3KBT C;  2FV0 A;  4ONT A;  4WU0 A;  5E1Q A;  3DYM A;  3J7H A;  3ALA A;  3DX0 A;  2G0D A;  1TNO B;  1FBO A;  2FYV A;  3Q7A B;  2WW1 A;  3BVW A;  1TN6 B;  2XWB B;  1HXK A;  2YFN A;  3DCD A;  3PGB A;  2H6I B;  2WZS A;  3T2P A;  3KBU C;  1HN0 A;  1TNZ B;  1FT2 B;  4OZV A;  1XW2 A;  1IA7 A;  1NSS A;  1N7P A;  3UD1 A;  3HI7 A;  1QX1 A;  1H37 A;  5DGR A;  3RX5 A;  4BOJ A;  1OJO A;  1F9D A;  1N1B A;  2IEJ B;  3Q7F B;  3PQI A;  3PZ3 B;  1NSX A;  1JCS B;  2WCO A;  1N7O A;  1JZ6 A;  2CWU A;  3MWX A;  3PMM A;  1JYW A;  1UT9 A;  2FUT A;  1K72 A;  3DSU B;  2CWT A;  3VD7 A;  2WYH A;  3WA2 X;  3RX8 A;  1L7J A;  2Z07 A;  3TY1 A;  1LF9 A;  4TF4 A;  1IQX A;  3DSV B;  5ILY A;  2XWJ B;  2ZXQ A;  1RKY A;  1C82 A;  1GHQ A;  1EKM A;  5DHK A;  1TQS A;  3WUX A;  1KFG A;  3H7L A;  3DYP A;  1JZ3 A;  3T2Q A;  4FUS A;  1Z45 A;  1RWC A;  3D5S A;  1FAE A;  3NJX A;  1TXK A;  3I3D A;  1JZ2 A;  3CU7 A;  3NBJ A;  1KSC A;  3KSQ B;  1HXA A;  3DX4 A;  3BS6 A;  2C10 A;  4BTW A;  5CA3 A;  3CZJ A;  3EJP A;  3BVV A;  1SA5 B;  3LVT A;  2ZBL A;  3DX3 A;  3ECQ A;  3VSM A;  1NS7 A;  1CB8 A;  3SFY B;  1HTY A;  5IK9 A;  1IVV A;  1N9A B;  3SFX B;  3OXU A;  3WIW A;  3W5N A;  3K25 A;  1JZ7 A;  2DRO A;  4DLQ A;  4V1S A;  2ALW A;  3VD3 A;  1VD5 A;  1WU5 A;  3OS7 A;  1HXC A;  5FO8 B;  2CWV A;  4EL8 A;  3OED A;  1W3Y A;  5AGD A;  1NSU A;  2JKA A;  1X1I A;  4D8O A;  3Q79 B;  1MMZ A;  3M7C A;  5M7I A;  1CEM A;  2RI8 A;  2Q1F A;  4Z4J A;  4DUV A;  1N94 B;  1RWF A;  3W7S A;  4AQ0 A;  3Q1N A;  3S4D A;  1FPP B;  1J0N A;  1NI1 B;  2BED B;  3CIH A;  3K11 A;  1PU4 A;  3RRS A;  1L1Y A;  2H6F B;  1HM2 A;  3DDF A;  1JYN A;  3M71 A;  3VD9 A;  1O5M B;  2XN0 A;  1JYX A;  1DL2 A;  3PZ2 B;  4MMH A;  2WVX B;  3DX1 A;  4FNT A;  3M01 A;  1KS8 A;  1N7N A;  4BZH A;  4OJZ A;  3ON6 A;  1NXC A;  4D71 A;  4E1Y A;  2F6D A;  2RI9 A;  1KZO B;  1H36 A;  1V7V A;  4OZW A;  1HN1 A;  1JYV A;  3BUP A;  4L6X A;  1NS8 A;  2KXR A;  2A73 B;  5M7Y A;  4DUX A;  2XFG A;  1LF6 A;  1UMP A;  2SQC A;  4RNQ A;  4EHM B;  1S64 B;  3SDR A;  2C11 A;  3BLB A;  4LNG B;  1TN8 B;  2PN5 A;  3TF4 A;  2E24 A;  3A0O A;  4BZF A;  5IKA A;  3PZ4 B;  1X81 B;  4Z4L A;  2AHG A;  2B4F A;  2BB5 A;  3SXX A;  2V8K A;  3W7X A;  4MMI A;  5IK0 A;  3SX1 A;  1FBW A;  2D73 A;  4FNU A;  3G4D A;  3T0U A;  2YIK A;  3ACT A;  1QAZ A;  3NJV A;  4GTS B;  4FNQ A;  4D4B A;  1N4S B;  3BUQ A;  2XHN A;  3W5M A;  3M74 A;  1HWW A;  2ZIR B;  1LXM A;  3D52 A;  5CZL A;  3M78 A;  5IL3 A;  3SEP A;  2WVX A;  1TQU A;  1H3B A;  1SNZ A;  3Q73 B;  1F1S A;  5IKH A;  2WMJ A;  4QT9 A;  4WVB A;  3WC3 A;  3KQ4 A;  2V3N A;  3S4B A;  4D1I A;  3DYO A;  1O1S B;  2R2L B;  4D6D A;  4KFD A;  4BZG A;  4BTX A;  4DI5 A;  3GLY A;  1IA6 A;  3E7J A;  4FNV A;  2JG0 A;  2VN4 A;  3T0B A;  1FO3 A;  3W7U A;  1MN0 A;  1IU7 A;  3E32 B;  3VSN A;  1N20 A;  1OAC A;  2ONH A;  3M76 A;  3WKF A;  1RWA A;  2AFA A;  4D4D A;  2FBA A;  1L2A A;  1F4H A;  1YGA A;  4Q2B A;  2CIR A;  3QXQ A;  1D6U A;  3BUB A;  4OK2 A;  2D5J A;  3P5P A;  2WYN A;  1UI7 A;  1QBQ B;  3PYB A;  4GTR B;  5FOB B;  1N24 A;  1GXM A;  4BOK A;  1W5Z A;  1N21 A;  2JF4 A;  1WMO A;  4K35 A;  4CJ1 A;  3HXB B;  4YCR A;  1NSV A;  3X3Z A;  2EAD A;  2WOH A;  1FO2 A;  1HZF A;  1O6Q A;  1N9E A;  1TN7 B;  1OJN A;  4ZH5 A;  1V5C A;  1QWU A;  2XSG A;  2XQW A;  3N0G A;  1N7Q A;  4FNR A;  2WY7 A;  1IQY A;  3QT3 A;  4MBG B;  3H3K A;  3QPF A;  1O6H A;  3QSP A;  1HX9 A;  2F7Q A;  4DLO A;  1W7C A;  3VDA A;  4EV5 A;  1MMX A;  3SQC A;  3Q78 B;  2AHF A;  1DOG A;  3QXF A;  2YFO A;  1O7D D;  2CFG A;  2F1A A;  3Q75 B;  1OJM A;  3WA3 A;  1N1Z A;  2WMF A;  3E34 B;  1S63 B;  5EAU A;  1JCR B;  3PYA A;  2PMV A;  3NBB A;  4GTQ B;  3DST B;  3DSW B;  3E80 A;  3QR8 A;  1PX4 A;  1GAI A;  1W6J A;  2E22 A;  3ANI A;  5ILJ A;  3CZN A;  3T0A A;  3C72 B;  3BUD A;  1LXK A;  2Y73 A;  1F9O A;  1DP0 A;  1GLM A;  1HMW A;  1JS4 A;  1NS0 A;  4DUW A;  4L0G A;  5IL8 A;  1W6G A;  3BVU A;  3VDB A;  1RWG A;  4M76 A;  3SDU A;  2OOV C;  3DDG A;  1TNU B;  1GAH A;  1RJO A;  3DSX B;  3K7X A;  3HIG A;  5EAS A;  4GTO B;  1H39 A;  2E2V A;  3BVT A;  1JZ4 A;  1TU5 A;  1V7X A;  2BB6 A;  4LNV A;  1NSR A;  3K5T A;  2PNC A;  3A24 A;  3E33 B;  5E2J A;  3LZ9 A;  5IM1 A;  4GTT B;  3D3I A;  3SDT A;  3CV5 A;  1O1T B;  3M75 A;  3HXF B;  4D6G A;  1N4Q B;  4KKI A;  1O1R B;  1RQ5 A;  2DRQ A;  1IVW A;  3I3E A;  1GA2 A;  3EQA A;  3WKH A;  1WMP A;  3VW5 A;  2CG1 A;  1NSM A;  2WOF A;  3QWT A;  3SDV A;  1H35 A;  4AYO A;  4ZRQ A;  1SA4 B;  2D1W A;  1LUR A;  2H6G B;  2X03 A;  3DPY B;  1N4P B;  1K1Y A;  5MEH A;  3DX2 A;  4C1S A;  2BT3 A;  2EAC A;  1MZC B;  1QAL A;  4FJQ A;  1H12 A;  1LTX B;  1V7W A;  1LOH A;  2F0Y B;  2ONG A;  1OJP A;  3X40 A;  3I3B A;  1O6R A;  4D4A A;  3MI6 A;  1XWT A;  1HM3 A;  1AYX A;  1IVX A;  1WMN A;  1W4N A;  1I8Q A;  1KRF A;  3IMH A;  2P0V A;  2WDA A;  3M72 A;  5CD2 A;  4FXG B;  5GW7 A;  4WVA A;  1AVK A;  1IS9 A;  1US1 A;  2G02 A;  3WFA A;  3NFV A;  5ILD A;  3EJT A;  5KKB A;  2V3P A;  2OW6 A;  1G9G A;  2DRR A;  3M7L A;  1F4A A;  3ACS A;  1W2Z A;  1H13 A;  1G9J A;  3M7E A;  1D6Z A;  3D50 A;  1H3A A;  3W7W A;  2CQT A;  3P5R A;  1UG9 A;  1X1H A;  3EJQ A;  3T08 A;  5C05 A;  2V8J A;  3RSY A;  2WIN B;  3X41 A;  2CIQ A;  3S9V A;  3BUI A;  1W6C A;  4D6J A;  4D4C A;  3H2W A;  1GSZ A;  4ZRP A;  1KSD A;  1SQC A;  2CFD A;  4L9P B;  1NS2 A;  2V8I A;  1EGU A;  4UFC A;  2EAB A;  3RJ3 A;  3MUY 1;  1AGM A;  5GY3 A;  4AYQ A;  2FV1 A;  1IVU A;  2OQE C;  2WVY A;  3D51 A;  1HV6 A;  1N23 A;  3DRA B;  2D8L A;  2OKX A;  3OB8 A;  2WY8 A;  4FNS A;  1D6Y A;  1WZZ A;  4XUV A;  3BVX A;  1HMU A;  2CFL A;  4D6C A;  2WW3 A;  1NSZ A; 
#chains in the Genus database with same CATH homology
 1PX4 A;  2WW2 A;  4DUV A;  1RWF A;  2E22 A;  4AQ0 A;  3Q1N A;  3T0A A;  1J0N A;  1LXK A;  3IAP A;  3WVF A;  1DP0 A;  1RW9 A;  1HMW A;  1NS0 A;  1HM2 A;  1JYN A;  1F9G A;  4DUW A;  3VD9 A;  1JYX A;  4MMH A;  2WVX B;  3VDB A;  1RWG A;  2HTB A;  4NEI A;  1N7N A;  2JKP A;  1PX3 A;  4BZH A;  4OJZ A;  4D71 A;  4E1Y A;  2WMI A;  1JZ4 A;  3MV0 1;  1NSR A;  3T09 A;  1HN1 A;  4OZW A;  4D72 A;  3VD5 A;  3A24 A;  1JYV A;  1J0M A;  1NS8 A;  2BRW A;  1X1J A;  3NRE A;  1ULV A;  5JMF A;  2BRV X;  3DEC A;  4DUX A;  1LF6 A;  3E1F 1;  5JMD A;  4D6G A;  1MMU A;  3BLC A;  4TTG A;  2E24 A;  4D6E A;  3A0O A;  2WMK A;  3I3E A;  3VDC A;  4BZF A;  1SO0 A;  1NSM A;  2WMG A;  4MMI A;  4F13 A;  1LUR A;  2D73 A;  2X03 A;  3OBA A;  1QAZ A;  1K1Y A;  3NJV A;  3T0D A;  1K1X A;  2WVZ A;  2XHN A;  5E1Q A;  3DYM A;  3J7H A;  1NS4 A;  2WW1 A;  1LOH A;  3AFL A;  1OJP A;  3DCD A;  3I3B A;  1LXM A;  2WZS A;  1JZ5 A;  3T2P A;  1HM3 A;  1HN0 A;  3SEP A;  2WVX A;  4OZV A;  1YQ2 A;  1NSS A;  2HTA A;  1SNZ A;  1N7P A;  4BZE A;  4RNL A;  1F1S A;  1I8Q A;  2WMJ A;  3IMH A;  3DYO A;  1OJO A;  1NSX A;  2WDA A;  4D6D A;  4BZG A;  3MUZ 1;  2FUQ A;  2WCO A;  1N7O A;  1JZ6 A;  3MWX A;  3E7J A;  4FNV A;  1JYW A;  2FUT A;  3VD7 A;  3T0B A;  3NFV A;  3WFA A;  1JOV A;  1L7J A;  1MN0 A;  1MMY A;  3TY1 A;  1LF9 A;  2CIS A;  3VSN A;  2JKE A;  1F4A A;  1RWA A;  1YGA A;  1F4H A;  2CIR A;  2ZXQ A;  1C82 A;  2WMH A;  3NNB A;  4OK2 A;  1JZ8 A;  4OK4 A;  1X1H A;  1UG9 A;  1RWH A;  3DYP A;  1JZ3 A;  3T08 A;  3T2Q A;  2ZQ0 A;  1N7R A;  1Z45 A;  1L7K A;  1RWC A;  3NJX A;  1TXK A;  3I3D A;  2CIQ A;  1JZ2 A;  3MV1 1;  4D6J A;  1NSV A;  2BRP A;  3BS6 A;  2WMI B;  1OJN A;  4F10 A;  2XSG A;  3CZJ A;  1K1W A;  4D6I A;  1N7Q A;  1NS2 A;  3ECQ A;  3VSM A;  1EGU A;  1CB8 A;  1NS7 A;  1JZ7 A;  3IAQ A;  3VDA A;  3BGA A;  3K25 A;  3MUY 1;  4D6H A;  1MMX A;  2WW0 A;  3VD3 A;  4J5T A;  2WVY A;  1HV6 A;  3OS7 A;  3OB8 A;  1W3Y A;  1OJM A;  1NSU A;  3T2O A;  5A1A A;  2JKA A;  1X1I A;  2WMF A;  1NKG A;  3VD4 A;  1MMZ A;  1HMU A;  4D6F A;  4D6C A;  2WW3 A;  1NSZ A;  3E80 A;  2Q1F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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