1W3YA

Crystal structure of s. pneumoniae hyaluronate lyase in complex with palmitoyl-vitamin c
Total Genus 254
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
721
structure length
721
Chain Sequence
b'VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title L-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor: X-Ray Structure and Molecular Modeling of Enzyme-Inhibitor Complexes
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 254
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2004-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1w3yA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1w3yA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1w3yA01
1I8QA 1MMXA 2FUTA 3DECA 2Q1FA 3T0DA 1N7RA 1JOVA 5A1AA 3DYPA 4OJZA 2WVZA 1JYWA 3VD9A 3IAQA 1N7OA 1RWAA 3NJXA 4BZHA 1LF6A 1OJOA 2X03A 3I3EA 1Z45A 1NSXA 1F9GA 1JZ8A 1C82A 4OK2A 1MMZA 1NS7A 3T08A 3E7JA 1JZ3A 1NS8A 4D6EA 1RWHA 1N7NA 1RWCA 1NSSA 4D6GA 2CIRA 1JZ5A 1RW9A 2JKEA 1L7KA 1NSVA 2BRWA 1F4AA 3I3DA 1MMUA 2JKPA 4NEIA 3A0OA 2WMIB 1N7PA 1HN1A 2WMIA 2WW3A 1LF9A 1OJNA 1W3YA 1SNZA 1F1SA 2CIQA 1JYXA 1QAZA 3J7HA 2WW1A 3IMHA 3VDAA 4BZFA 1J0NA 1F4HA 2WW2A 3MV11 1TXKA 1RWFA 4TTGA 4OK4A 4D6HA 3VDCA 4E1YA 3VD3A 2WMKA 2BRPA 1K1YA 1NS0A 1SO0A 1PX4A 3MUZ1 3T0AA 1JYNA 4D6CA 3DYOA 3OB8A 3AFLA 4MMIA 2WZSA 1NS2A 1HM2A 1YQ2A 3VSMA 3NJVA 2WMHA 3NREA 1K1XA 2WMGA 4DUXA 3DYMA 1OJPA 5JMFA 4D6FA 1NKGA 4D71A 2WVXB 3IAPA 2WVXA 3NNBA 4D6IA 2JKAA 1EGUA 2WVYA 4RNLA 3VD7A 3MV01 1JZ6A 3BGAA 1HV6A 1X1HA 3Q1NA 1HN0A 1X1IA 3VD4A 4D6JA 2ZQ0A 1JZ4A 3CZJA 1X1JA 3OS7A 1HMUA 2XHNA 3VD5A 3A24A 1YGAA 2HTAA 1HM3A 1OJMA 3E80A 1RWGA 2D73A 3I3BA 4D72A 3T2PA 1NSZA 1MN0A 4BZEA 3T0BA 3ECQA 3NFVA 1UG9A 1LXKA 3SEPA 1N7QA 4F10A 1LURA 5E1QA 1MMYA 4D6DA 2BRVX 2WMFA 2FUQA 4F13A 1LOHA 4DUWA 1NSUA 3MWXA 2WDAA 4BZGA 3VDBA 3VSNA 2E24A 4MMHA 1NS4A 2WCOA 5JMDA 1NSRA 3K25A 3WFAA 1PX3A 1CB8A 4FNVA 2WMJA 2ZXQA 1JZ2A 3T2QA 2HTBA 1NSMA 2WW0A 2E22A 1J0MA 4OZWA 1DP0A 3OBAA 1L7JA 3T09A 4AQ0A 1LXMA 1K1WA 4OZVA 2XSGA 3MUY1 1HMWA 2CISA 1ULVA 3E1F1 4DUVA 1JZ7A 1JYVA 3T2OA 3DCDA
chains in the Genus database with same CATH superfamily
1R34A 3QDEA 1MMXA 3D52A 4Z4JA 1O7DD 2WVZA 1JYWA 3VD9A 1N7OA 5DHIA 1O5MB 3NJXA 5ILKA 4D8OA 1Z45A 1F9GA 4L0GA 1C82A 4ZH1A 3OEDA 4ZG8A 1UMPA 5M7IA 3DSUB 3S4AA 3QT9A 1RW9A 2JKEA 1L7KA 3X17A 1N1ZA 3KQ4A 3I3DA 4DI5A 1R76A 1HWWA 2CFGA 3EJPA 3DSXB 1TNZB 3A0OA 2JJBA 2RGKA 3DPYB 4ZH5A 1NXCA 3W7SA 2WW3A 4Q88A 4BOKA 3BVXA 3AFJA 3KSQB 2CG0A 1X81B 1KS8A 1H13A 3E32B 1IU7A 4DOEA 3IMHA 3M00A 2DRSA 1G9GA 3EU5B 2EADA 3MV11 3UD2A 1W2ZA 2WMKA 1NS0A 2OOVC 1SO0A 1PX4A 3T0AA 1GXOA 1KSIA 1JYNA 4D6CA 2ZZRA 3M7LA 3ACTA 4MMIA 2CWUA 1UI8A 4KFDA 3KBTC 1NS2A 3E6UA 3VSMA 1A2VA 3NJVA 3DDGA 3HI7A 2WMGA 3CV5A 4YDEB 2WVXB 1O1TB 5M7YA 1JS4A 3NNBA 4Q2BA 2WVXA 3X3ZA 1WU6A 4AYPA 2JKAA 1EGUA 1GXMA 3N0GA 3BUDA 3RX8A 1X1HA 2F7QA 2WYIA 2YFOA 1X1IA 3Q1NA 3VD4A 4D6JA 2ZQ0A 3U7VA 1JZ4A 3CZJA 2XHNA 4YDOB 3OXUA 3W7TA 3A24A 1UT9A 2BEDB 1G87A 2EABA 2A73B 3M78A 3WA3A 2YFNA 1KREA 3E80A 3BVWA 3LVTA 3SXXA 1H3BA 4FNQA 1W6GA 4V1RA 3E30B 1HCUA 3T0BA 3BS6A 3ECQA 2D1WA 1QALA 4MBGB 1DCEB 2F18A 1IQYA 1LURA 1QWUA 5E1QA 1H54A 4D6DA 3DRAB 5ILIA 2WMFA 4D1JA 1FMIA 2FUQA 2EACA 1LOHA 4F13A 2F0YB 5FO8B 3D51A 3M74A 1FO2A 3KN4A 3MWXA 1US1A 3VDBA 3BUIA 3DX2A 2B39A 2OW6A 4MMHA 4UFCA 3F59A 5JMDA 1TN8B 4KFEA 1IS9A 4Z4LA 3W7XA 3HXEB 2OQEA 5CA3A 1CB8A 3D4YA 4XUVA 2WMJA 1H14A 1FP3A 2FUZA 3G6JB 5FOBB 1IVWA 3A3VA 1EKMA 3RRSA 5IK9A 2CFLA 3N0FA 1F9DA 3PZ1B 2E2VA 3AMOB 1NI1B 4KFFA 3AMOA 1PU4A 3DSSB 4ONTA 1GAIA 3T09A 2PN5A 3H7LA 1RQ5A 3BUPA 1KWFA 3BVTA 1LXMA 3EUVB 5ILYA 1LD7B 3HXDB 3Q79B 1H35A 4DUVA 3S4DA 1WU4A 3T2OA 3DCDA 3QFZA 4BZEA 1I8QA 1HZFA 2FUTA 4DLOA 3EQAA 3CU7A 3M76A 3M73A 3DYPA 3T33A 3QT3A 5GW7A 5ILZA 1RJOA 2WOHA 2OW7A 2DROA 2XN0A 1FPPB 1VD5A 3CZNA 2XWJB 2YX9A 1JZ8A 1AGMA 4OK2A 3P5RA 1W6KA 1UI7A 1WU5A 2RI8A 1N7NA 4L9PB 4D6GA 1SPUA 4EL8A 1S64B 1MMUA 5CD2A 2JKPA 2GZ6A 3M7CA 2P0VA 1KZPB 2H6IB 2F7OA 1TNBB 1HTYA 2AHGA 1W3YA 1F1SA 1TNOB 5JPNB 3M02A 5EATA 2CIQA 1GAHA 1KKTA 2H6GB 3QPFA 3EJUA 1J0NA 3ALAA 1H39A 2F7RA 3PZ2B 4TTGA 4OK4A 3SAEA 1O6HA 3VXDA 1QAFA 1WMPA 4FNUA 3VDCA 4E1YA 3VD3A 2WY8A 4GAXA 1K1YA 3S4BA 1S63B 3WIRA 2E2UA 3ANJA 1H3CA 2WO0A 3OB8A 4FXKB 3AFLA 1KZOB 2F6DA 3DSVB 3X3YA 5GZKA 1FT1B 3Q75B 1KSCA 1D6ZA 1CLCA 1N1BA 3EJSA 1DL2A 3BVUA 1LVNA 4KTPA 4DUXA 3DYMA 2NVPA 3E34B 5JMFA 3DX3A 1GA2A 3Q78B 1L2AA 4GTSB 2C10A 1V7VA 2R2LB 4AYOA 3WKFA 5EASA 1N4RB 4FNRA 1QWNA 1AVKA 1HN0A 2BT3A 5KBPA 2FV1A 3OS7A 1HMUA 3QXQA 1N9AB 4FXGB 3VD5A 2ONGA 2CG1A 1OJMA 3I3BA 3BUQA 1FCEA 1AYXA 3RENA 1TNUB 1LXKA 3SEPA 1N7QA 1JCQB 1QSJA 2H6HB 1N22A 3ANKA 1C3DA 1WMOA 3DSWB 3KIIA 1AVLA 1NSUA 2CFWA 1TQUA 1V7WA 1N94B 2BBCA 3EU8A 1G9JA 2D8LA 1D6UA 1NSRA 3HIIA 3M72A 4BOJA 4FNVA 1PS3A 2WGQA 3E37B 3SDVA 1FT2B 1V5DA 4LIXA 1JZ2A 3T2QA 1JCSB 4D4AA 1G6IA 3PYBA 3HXBB 1J0MA 4OZWA 1OACA 1DP0A 4WVAA 3OBAA 1H36A 3H3KA 3X41A 1N4QB 3SDTA 1TQVA 3HXCB 5MEHA 3Q7FB 3Q7AB 2XSGA 2CFKA 5DGQA 1O6QA 1JYVA 1LD8B 3BUBA 1V7XA 3D5RA 2Q1FA 4AYQA 3T0DA 1N7RA 1JOVA 5A1AA 3D3IA 3GZKA 2SQCA 4OJZA 3IAQA 3KSLB 2ZBLA 2FYVA 2OQEC 3ANIA 1D8DB 1FAEA 3CZSA 3I3EA 1DYUA 1N4PB 2A8ZA 5IL3A 2Y73A 2ALWA 1MMZA 1NS7A 1JZ3A 3E7JA 4D6EA 3PZ4B 3K5TA 1NC5A 2YIKA 3WKGA 1NSSA 3DDFA 3LOYA 1NSVA 3P2CA 2Z07A 4FJQA 4KTRA 1SA5B 4CJ1A 3TY1A 2WY7A 2DRRA 4NEIA 1HX9A 2JG0A 1HN1A 2G0DA 3RX5A 1SNZA 4BTWA 3M77A 1SIHA 1QAZA 3J7HA 3SFXB 3M71A 1TQTA 3QWTA 1F4HA 1RWFA 4EV5A 2QNOA 1LTXB 5CZLA 2PMVA 2ZL8A 4D6HA 1DOGA 3D5SA 2IEJB 2BRPA 4CE7A 3DYOA 4TF4A 2WMHA 1CEMA 3NREA 2NOJA 1L1YA 1GLMA 4D6IA 3W5NA 2V3PA 5EAUA 4J5TA 3M01A 1TQWA 4RNLA 3WUXA 5ILDA 3RX7A 3C72B 3HXFB 3BGAA 2ZIRB 1HV6A 1W5ZA 3KLSA 5E2JA 1XW2A 3DX4A 3NBJA 5IM1A 3GLYA 1N21A 3W7UA 3SX1A 3S9VA 3GT5A 2HTAA 3BLCA 2D73A 1RWGA 5IKAA 1NL4B 1WZZA 1TQSA 2WIIB 1RKYA 2CWTA 1IVUA 3D50A 2XWBB 4GTQB 1MMYA 1N23A 2BRVX 2WINB 3QR8A 3W5MA 2KXRA 4DUWA 4BZGA 2DRQA 3VSNA 1SA4B 5GY3A 2WCOA 3WKHA 2F1AA 3KBUC 3TF4A 4YCRA 1SIIA 3MPHA 3G4FA 1AV4A 1IA7A 4WVBA 2WOFA 1HXGA 5ILHA 1N95B 1N9EA 2HTBA 1H3AA 3WC3A 2VN7A 1GHQA 2E22A 1QQFA 3ACSA 2CFDA 2OKXA 4WU0A 2VN4A 2D5JA 5KKBA 1L7JA 3X42A 4D4CA 3X40A 3EJRA 5FO9B 4K3AA 4AQ0A 4D94A 3QSPA 3P5PA 3NBBA 2XFGA 3PQIA 1K1WA 3QXFA 4OZVA 4FNTA 3M7EA 4JJJA 4FNSA 3BVVA 5ILJA 1R33A 1HXKA 1X9DA 1H12A 3E1F1 4L6XA 4K35A 1JZ7A 3QRYA 2AHFA 4AYRA 3S4CA 3DECA 3DX1A 2RDYA 3W7WA 2G02A 1IVXA 4ZRPA 4ZRQA 2GH4A 3ON6A 1RWAA 1LF6A 4BZHA 2CWVA 1F9OA 5JPMB 1WMNA 2OOVA 1OJOA 3SDRA 2X03A 3G4DA 4DODA 2E2TA 4MU9A 3SDQA 1NSXA 2JF4A 2ONHA 3T08A 1NS8A 1RWHA 5IK6A 4EV2A 2V8IA 1RWCA 4D4BA 1W7CA 2CIRA 1JZ5A 2AFAA 1H37A 2BRWA 1XWTA 1F4AA 3T0UA 1TF4A 4CJ0A 1GSZA 1W6JA 2WMIB 3SQCA 1N7PA 2V3NA 2WYHA 2WMIA 1LF9A 1OJNA 4D1IA 2XN1A 5IKHA 1D8EB 2GOXA 4WVCA 3PGBA 4BTXA 1JYXA 2WW1A 5AGDA 3D4ZA 3VDAA 1QAKA 4BZFA 2WW2A 1QX1A 1GXNA 1MZCB 3H2WA 4GTTB 1TXKA 2FBAA 3PYAA 4LNBB 1FBWA 4LNGB 3SDUA 3DSTB 3WIQA 5FO7B 4D4DA 3WIWA 3MUZ1 1O1SB 1N4SB 2C11A 2V8JA 3EJQA 3BLBA 1TNYB 2WZSA 1HM2A 1YQ2A 1K1XA 3QFYA 1OJPA 4D6FA 1NKGA 3E33B 4D71A 1W4NA 3WVFA 3IAPA 3X3XA 5IK0A 3RJ3A 5C05A 1KSDA 1O79A 2WVYA 3VD7A 3RSYA 1K72A 2RI9A 4GTRB 3MV01 1JZ6A 2F1BA 3PMMA 1JRQA 2PNCA 1FO3A 2BB5A 1HXCA 1KFGA 1X1JA 1O1RB 4FUSA 2V8KA 2F7PA 1YGAA 2I07B 2B4FA 2XN2A 1HM3A 2ZISB 3T2PA 4D72A 4RNQA 1NSZA 1MN0A 2W0QA 5DGRA 1V5CA 4GTVB 3NFVA 1UG9A 3DX0A 4F10A 1FBOA 5IL8A 4BTYA 5DHKA 1IA6A 2CQSA 2WDAA 3N9HA 1W6CA 2H6FB 3UD1A 2BB6A 1TN7B 1IVVA 2E24A 2KXSA 1NS4A 2FV0A 2J5CA 3MI6A 4KKIA 1D6YA 3K25A 3QG0A 3WFAA 1PX3A 3PZ3B 2WYNA 4V1SA 2Y74A 2ZXQA 1QBQB 3K11A 4EHMB 4LNVA 1NSMA 2WW0A 3M7BA 1JCRB 1KRFA 1N20A 1IQXA 4DLQA 1O6RA 1SQCA 3EJTA 3M75A 4KKJA 3HIGA 1TU5A 4GTMB 1HXAA 3LZ9A 3WKIA 3VW5A 3WA2X 4C1SA 4GTPB 4GTOB 4TXTA 2EAEA 2CQTA 2XQWA 3Q73B 1N24A 4QT9A 1XWQA 1TN6B 3MUY1 3K7XA 1HMWA 2CISA 4FNPA 1ULVA 3E73A 3CIHA 3EZ8A 4GL3A 3SFYB 4M76A
chains in the Genus database with same CATH topology
1I8QA 1MMXA 2FUTA 3DECA 2Q1FA 3T0DA 1N7RA 1JOVA 5A1AA 3DYPA 4OJZA 2WVZA 1JYWA 3VD9A 3IAQA 1N7OA 1RWAA 3NJXA 4BZHA 1LF6A 1OJOA 2X03A 3I3EA 1Z45A 1NSXA 1F9GA 1JZ8A 1C82A 4OK2A 1MMZA 1NS7A 3T08A 3E7JA 1JZ3A 1NS8A 4D6EA 1RWHA 1N7NA 1RWCA 1NSSA 4D6GA 2CIRA 1JZ5A 1RW9A 2JKEA 1L7KA 1NSVA 2BRWA 1F4AA 3I3DA 1MMUA 2JKPA 3TY1A 4NEIA 3A0OA 2WMIB 1N7PA 1HN1A 2WMIA 2WW3A 1LF9A 1OJNA 1W3YA 1SNZA 1F1SA 2CIQA 1JYXA 1QAZA 3J7HA 2WW1A 3IMHA 3VDAA 4BZFA 1J0NA 1F4HA 2WW2A 3MV11 1TXKA 1RWFA 4TTGA 4OK4A 4D6HA 3VDCA 4E1YA 3VD3A 2WMKA 2BRPA 1K1YA 1NS0A 1SO0A 1PX4A 3MUZ1 3T0AA 1JYNA 4D6CA 3DYOA 3OB8A 3AFLA 4MMIA 2WZSA 1NS2A 1HM2A 1YQ2A 3VSMA 3NJVA 2WMHA 3NREA 1K1XA 2WMGA 4DUXA 3DYMA 1OJPA 5JMFA 4D6FA 1NKGA 4D71A 2WVXB 3WVFA 3IAPA 2WVXA 3NNBA 4D6IA 4J5TA 2JKAA 1EGUA 2WVYA 4RNLA 3VD7A 3MV01 1JZ6A 3BGAA 1HV6A 1X1HA 3Q1NA 1HN0A 1X1IA 3VD4A 4D6JA 2ZQ0A 1JZ4A 3CZJA 1X1JA 3OS7A 1HMUA 2XHNA 3VD5A 3A24A 1YGAA 2HTAA 3BLCA 1HM3A 1OJMA 3E80A 1RWGA 2D73A 3I3BA 4D72A 3T2PA 1NSZA 1MN0A 4BZEA 3T0BA 3BS6A 3ECQA 3NFVA 1UG9A 1LXKA 3SEPA 1N7QA 4F10A 1LURA 5E1QA 1MMYA 4D6DA 2BRVX 2WMFA 2FUQA 4F13A 1LOHA 4DUWA 1NSUA 3MWXA 2WDAA 4BZGA 3VDBA 3VSNA 2E24A 4MMHA 1NS4A 2WCOA 5JMDA 1NSRA 3K25A 3WFAA 1PX3A 1CB8A 4FNVA 2WMJA 2ZXQA 1JZ2A 3T2QA 2HTBA 1NSMA 2WW0A 2E22A 1J0MA 4OZWA 1DP0A 3OBAA 1L7JA 3T09A 4AQ0A 1LXMA 1K1WA 4OZVA 2XSGA 3MUY1 1HMWA 2CISA 1ULVA 3E1F1 4DUVA 1JZ7A 1JYVA 3T2OA 3DCDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I8Q A;  1MMX A;  2FUT A;  3DEC A;  2Q1F A;  3T0D A;  1N7R A;  1JOV A;  5A1A A;  3DYP A;  4OJZ A;  2WVZ A;  1JYW A;  3VD9 A;  3IAQ A;  1N7O A;  1RWA A;  3NJX A;  4BZH A;  1LF6 A;  1OJO A;  2X03 A;  3I3E A;  1Z45 A;  1NSX A;  1F9G A;  1JZ8 A;  1C82 A;  4OK2 A;  1MMZ A;  1NS7 A;  3T08 A;  3E7J A;  1JZ3 A;  1NS8 A;  4D6E A;  1RWH A;  1N7N A;  1RWC A;  1NSS A;  4D6G A;  2CIR A;  1JZ5 A;  1RW9 A;  2JKE A;  1L7K A;  1NSV A;  2BRW A;  1F4A A;  3I3D A;  1MMU A;  2JKP A;  4NEI A;  3A0O A;  2WMI B;  1N7P A;  1HN1 A;  2WMI A;  2WW3 A;  1LF9 A;  1OJN A;  1W3Y A;  1SNZ A;  1F1S A;  2CIQ A;  1JYX A;  1QAZ A;  3J7H A;  2WW1 A;  3IMH A;  3VDA A;  4BZF A;  1J0N A;  1F4H A;  2WW2 A;  3MV1 1;  1TXK A;  1RWF A;  4TTG A;  4OK4 A;  4D6H A;  3VDC A;  4E1Y A;  3VD3 A;  2WMK A;  2BRP A;  1K1Y A;  1NS0 A;  1SO0 A;  1PX4 A;  3MUZ 1;  3T0A A;  1JYN A;  4D6C A;  3DYO A;  3OB8 A;  3AFL A;  4MMI A;  2WZS A;  1NS2 A;  1HM2 A;  1YQ2 A;  3VSM A;  3NJV A;  2WMH A;  3NRE A;  1K1X A;  2WMG A;  4DUX A;  3DYM A;  1OJP A;  5JMF A;  4D6F A;  1NKG A;  4D71 A;  2WVX B;  3IAP A;  2WVX A;  3NNB A;  4D6I A;  2JKA A;  1EGU A;  2WVY A;  4RNL A;  3VD7 A;  3MV0 1;  1JZ6 A;  3BGA A;  1HV6 A;  1X1H A;  3Q1N A;  1HN0 A;  1X1I A;  3VD4 A;  4D6J A;  2ZQ0 A;  1JZ4 A;  3CZJ A;  1X1J A;  3OS7 A;  1HMU A;  2XHN A;  3VD5 A;  3A24 A;  1YGA A;  2HTA A;  1HM3 A;  1OJM A;  3E80 A;  1RWG A;  2D73 A;  3I3B A;  4D72 A;  3T2P A;  1NSZ A;  1MN0 A;  4BZE A;  3T0B A;  3ECQ A;  3NFV A;  1UG9 A;  1LXK A;  3SEP A;  1N7Q A;  4F10 A;  1LUR A;  5E1Q A;  1MMY A;  4D6D A;  2BRV X;  2WMF A;  2FUQ A;  4F13 A;  1LOH A;  4DUW A;  1NSU A;  3MWX A;  2WDA A;  4BZG A;  3VDB A;  3VSN A;  2E24 A;  4MMH A;  1NS4 A;  2WCO A;  5JMD A;  1NSR A;  3K25 A;  3WFA A;  1PX3 A;  1CB8 A;  4FNV A;  2WMJ A;  2ZXQ A;  1JZ2 A;  3T2Q A;  2HTB A;  1NSM A;  2WW0 A;  2E22 A;  1J0M A;  4OZW A;  1DP0 A;  3OBA A;  1L7J A;  3T09 A;  4AQ0 A;  1LXM A;  1K1W A;  4OZV A;  2XSG A;  3MUY 1;  1HMW A;  2CIS A;  1ULV A;  3E1F 1;  4DUV A;  1JZ7 A;  1JYV A;  3T2O A;  3DCD A; 
#chains in the Genus database with same CATH topology
 1R34 A;  3QDE A;  1MMX A;  3D52 A;  4Z4J A;  1O7D D;  2WVZ A;  1JYW A;  3VD9 A;  1N7O A;  5DHI A;  1O5M B;  3NJX A;  5ILK A;  4D8O A;  1Z45 A;  1F9G A;  4L0G A;  1C82 A;  4ZH1 A;  3OED A;  4ZG8 A;  1UMP A;  5M7I A;  3DSU B;  3S4A A;  3QT9 A;  1RW9 A;  2JKE A;  1L7K A;  3X17 A;  1N1Z A;  3KQ4 A;  3I3D A;  4DI5 A;  1R76 A;  1HWW A;  2CFG A;  3EJP A;  3DSX B;  1TNZ B;  3A0O A;  2JJB A;  2RGK A;  3DPY B;  4ZH5 A;  1NXC A;  3W7S A;  2WW3 A;  4Q88 A;  4BOK A;  3BVX A;  3AFJ A;  3KSQ B;  2CG0 A;  1X81 B;  1KS8 A;  1H13 A;  3E32 B;  1IU7 A;  4DOE A;  3IMH A;  3M00 A;  2DRS A;  1G9G A;  3EU5 B;  2EAD A;  3MV1 1;  3UD2 A;  1W2Z A;  2WMK A;  1NS0 A;  2OOV C;  1SO0 A;  1PX4 A;  3T0A A;  1GXO A;  1KSI A;  1JYN A;  4D6C A;  2ZZR A;  3M7L A;  3ACT A;  4MMI A;  2CWU A;  1UI8 A;  4KFD A;  3KBT C;  1NS2 A;  3E6U A;  3VSM A;  1A2V A;  3NJV A;  3DDG A;  3HI7 A;  2WMG A;  3CV5 A;  4YDE B;  2WVX B;  1O1T B;  5M7Y A;  1JS4 A;  3NNB A;  4Q2B A;  2WVX A;  3X3Z A;  1WU6 A;  4AYP A;  2JKA A;  1EGU A;  1GXM A;  3N0G A;  3BUD A;  3RX8 A;  1X1H A;  2F7Q A;  2WYI A;  2YFO A;  1X1I A;  3Q1N A;  3VD4 A;  4D6J A;  2ZQ0 A;  3U7V A;  1JZ4 A;  3CZJ A;  2XHN A;  4YDO B;  3OXU A;  3W7T A;  3A24 A;  1UT9 A;  2BED B;  1G87 A;  2EAB A;  2A73 B;  3M78 A;  3WA3 A;  2YFN A;  1KRE A;  3E80 A;  3BVW A;  3LVT A;  3SXX A;  1H3B A;  4FNQ A;  1W6G A;  4V1R A;  3E30 B;  1HCU A;  3T0B A;  3BS6 A;  3ECQ A;  2D1W A;  1QAL A;  4MBG B;  1DCE B;  2F18 A;  1IQY A;  1LUR A;  1QWU A;  5E1Q A;  1H54 A;  4D6D A;  3DRA B;  5ILI A;  2WMF A;  4D1J A;  1FMI A;  2FUQ A;  2EAC A;  1LOH A;  4F13 A;  2F0Y B;  5FO8 B;  3D51 A;  3M74 A;  1FO2 A;  3KN4 A;  3MWX A;  1US1 A;  3VDB A;  3BUI A;  3DX2 A;  2B39 A;  2OW6 A;  4MMH A;  4UFC A;  3F59 A;  5JMD A;  1TN8 B;  4KFE A;  1IS9 A;  4Z4L A;  3W7X A;  3HXE B;  2OQE A;  5CA3 A;  1CB8 A;  3D4Y A;  4XUV A;  2WMJ A;  1H14 A;  1FP3 A;  2FUZ A;  3G6J B;  5FOB B;  1IVW A;  3A3V A;  1EKM A;  3RRS A;  5IK9 A;  2CFL A;  3N0F A;  1F9D A;  3PZ1 B;  2E2V A;  3AMO B;  1NI1 B;  4KFF A;  3AMO A;  1PU4 A;  3DSS B;  4ONT A;  1GAI A;  3T09 A;  2PN5 A;  3H7L A;  1RQ5 A;  3BUP A;  1KWF A;  3BVT A;  1LXM A;  3EUV B;  5ILY A;  1LD7 B;  3HXD B;  3Q79 B;  1H35 A;  4DUV A;  3S4D A;  1WU4 A;  3T2O A;  3DCD A;  3QFZ A;  4BZE A;  1I8Q A;  1HZF A;  2FUT A;  4DLO A;  3EQA A;  3CU7 A;  3M76 A;  3M73 A;  3DYP A;  3T33 A;  3QT3 A;  5GW7 A;  5ILZ A;  1RJO A;  2WOH A;  2OW7 A;  2DRO A;  2XN0 A;  1FPP B;  1VD5 A;  3CZN A;  2XWJ B;  2YX9 A;  1JZ8 A;  1AGM A;  4OK2 A;  3P5R A;  1W6K A;  1UI7 A;  1WU5 A;  2RI8 A;  1N7N A;  4L9P B;  4D6G A;  1SPU A;  4EL8 A;  1S64 B;  1MMU A;  5CD2 A;  2JKP A;  2GZ6 A;  3M7C A;  2P0V A;  1KZP B;  2H6I B;  2F7O A;  1TNB B;  1HTY A;  2AHG A;  1W3Y A;  1F1S A;  1TNO B;  5JPN B;  3M02 A;  5EAT A;  2CIQ A;  1GAH A;  1KKT A;  2H6G B;  3QPF A;  3EJU A;  1J0N A;  3ALA A;  1H39 A;  2F7R A;  3PZ2 B;  4TTG A;  4OK4 A;  3SAE A;  1O6H A;  3VXD A;  1QAF A;  1WMP A;  4FNU A;  3VDC A;  4E1Y A;  3VD3 A;  2WY8 A;  4GAX A;  1K1Y A;  3S4B A;  1S63 B;  3WIR A;  2E2U A;  3ANJ A;  1H3C A;  2WO0 A;  3OB8 A;  4FXK B;  3AFL A;  1KZO B;  2F6D A;  3DSV B;  3X3Y A;  5GZK A;  1FT1 B;  3Q75 B;  1KSC A;  1D6Z A;  1CLC A;  1N1B A;  3EJS A;  1DL2 A;  3BVU A;  1LVN A;  4KTP A;  4DUX A;  3DYM A;  2NVP A;  3E34 B;  5JMF A;  3DX3 A;  1GA2 A;  3Q78 B;  1L2A A;  4GTS B;  2C10 A;  1V7V A;  2R2L B;  4AYO A;  3WKF A;  5EAS A;  1N4R B;  4FNR A;  1QWN A;  1AVK A;  1HN0 A;  2BT3 A;  5KBP A;  2FV1 A;  3OS7 A;  1HMU A;  3QXQ A;  1N9A B;  4FXG B;  3VD5 A;  2ONG A;  2CG1 A;  1OJM A;  3I3B A;  3BUQ A;  1FCE A;  1AYX A;  3REN A;  1TNU B;  1LXK A;  3SEP A;  1N7Q A;  1JCQ B;  1QSJ A;  2H6H B;  1N22 A;  3ANK A;  1C3D A;  1WMO A;  3DSW B;  3KII A;  1AVL A;  1NSU A;  2CFW A;  1TQU A;  1V7W A;  1N94 B;  2BBC A;  3EU8 A;  1G9J A;  2D8L A;  1D6U A;  1NSR A;  3HII A;  3M72 A;  4BOJ A;  4FNV A;  1PS3 A;  2WGQ A;  3E37 B;  3SDV A;  1FT2 B;  1V5D A;  4LIX A;  1JZ2 A;  3T2Q A;  1JCS B;  4D4A A;  1G6I A;  3PYB A;  3HXB B;  1J0M A;  4OZW A;  1OAC A;  1DP0 A;  4WVA A;  3OBA A;  1H36 A;  3H3K A;  3X41 A;  1N4Q B;  3SDT A;  1TQV A;  3HXC B;  5MEH A;  3Q7F B;  3Q7A B;  2XSG A;  2CFK A;  5DGQ A;  1O6Q A;  1JYV A;  1LD8 B;  3BUB A;  1V7X A;  3D5R A;  2Q1F A;  4AYQ A;  3T0D A;  1N7R A;  1JOV A;  5A1A A;  3D3I A;  3GZK A;  2SQC A;  4OJZ A;  3IAQ A;  3KSL B;  2ZBL A;  2FYV A;  2OQE C;  3ANI A;  1D8D B;  1FAE A;  3CZS A;  3I3E A;  1DYU A;  1N4P B;  2A8Z A;  5IL3 A;  2Y73 A;  2ALW A;  1MMZ A;  1NS7 A;  1JZ3 A;  3E7J A;  4D6E A;  3PZ4 B;  3K5T A;  1NC5 A;  2YIK A;  3WKG A;  1NSS A;  3DDF A;  3LOY A;  1NSV A;  3P2C A;  2Z07 A;  4FJQ A;  4KTR A;  1SA5 B;  4CJ1 A;  3TY1 A;  2WY7 A;  2DRR A;  4NEI A;  1HX9 A;  2JG0 A;  1HN1 A;  2G0D A;  3RX5 A;  1SNZ A;  4BTW A;  3M77 A;  1SIH A;  1QAZ A;  3J7H A;  3SFX B;  3M71 A;  1TQT A;  3QWT A;  1F4H A;  1RWF A;  4EV5 A;  2QNO A;  1LTX B;  5CZL A;  2PMV A;  2ZL8 A;  4D6H A;  1DOG A;  3D5S A;  2IEJ B;  2BRP A;  4CE7 A;  3DYO A;  4TF4 A;  2WMH A;  1CEM A;  3NRE A;  2NOJ A;  1L1Y A;  1GLM A;  4D6I A;  3W5N A;  2V3P A;  5EAU A;  4J5T A;  3M01 A;  1TQW A;  4RNL A;  3WUX A;  5ILD A;  3RX7 A;  3C72 B;  3HXF B;  3BGA A;  2ZIR B;  1HV6 A;  1W5Z A;  3KLS A;  5E2J A;  1XW2 A;  3DX4 A;  3NBJ A;  5IM1 A;  3GLY A;  1N21 A;  3W7U A;  3SX1 A;  3S9V A;  3GT5 A;  2HTA A;  3BLC A;  2D73 A;  1RWG A;  5IKA A;  1NL4 B;  1WZZ A;  1TQS A;  2WII B;  1RKY A;  2CWT A;  1IVU A;  3D50 A;  2XWB B;  4GTQ B;  1MMY A;  1N23 A;  2BRV X;  2WIN B;  3QR8 A;  3W5M A;  2KXR A;  4DUW A;  4BZG A;  2DRQ A;  3VSN A;  1SA4 B;  5GY3 A;  2WCO A;  3WKH A;  2F1A A;  3KBU C;  3TF4 A;  4YCR A;  1SII A;  3MPH A;  3G4F A;  1AV4 A;  1IA7 A;  4WVB A;  2WOF A;  1HXG A;  5ILH A;  1N95 B;  1N9E A;  2HTB A;  1H3A A;  3WC3 A;  2VN7 A;  1GHQ A;  2E22 A;  1QQF A;  3ACS A;  2CFD A;  2OKX A;  4WU0 A;  2VN4 A;  2D5J A;  5KKB A;  1L7J A;  3X42 A;  4D4C A;  3X40 A;  3EJR A;  5FO9 B;  4K3A A;  4AQ0 A;  4D94 A;  3QSP A;  3P5P A;  3NBB A;  2XFG A;  3PQI A;  1K1W A;  3QXF A;  4OZV A;  4FNT A;  3M7E A;  4JJJ A;  4FNS A;  3BVV A;  5ILJ A;  1R33 A;  1HXK A;  1X9D A;  1H12 A;  3E1F 1;  4L6X A;  4K35 A;  1JZ7 A;  3QRY A;  2AHF A;  4AYR A;  3S4C A;  3DEC A;  3DX1 A;  2RDY A;  3W7W A;  2G02 A;  1IVX A;  4ZRP A;  4ZRQ A;  2GH4 A;  3ON6 A;  1RWA A;  1LF6 A;  4BZH A;  2CWV A;  1F9O A;  5JPM B;  1WMN A;  2OOV A;  1OJO A;  3SDR A;  2X03 A;  3G4D A;  4DOD A;  2E2T A;  4MU9 A;  3SDQ A;  1NSX A;  2JF4 A;  2ONH A;  3T08 A;  1NS8 A;  1RWH A;  5IK6 A;  4EV2 A;  2V8I A;  1RWC A;  4D4B A;  1W7C A;  2CIR A;  1JZ5 A;  2AFA A;  1H37 A;  2BRW A;  1XWT A;  1F4A A;  3T0U A;  1TF4 A;  4CJ0 A;  1GSZ A;  1W6J A;  2WMI B;  3SQC A;  1N7P A;  2V3N A;  2WYH A;  2WMI A;  1LF9 A;  1OJN A;  4D1I A;  2XN1 A;  5IKH A;  1D8E B;  2GOX A;  4WVC A;  3PGB A;  4BTX A;  1JYX A;  2WW1 A;  5AGD A;  3D4Z A;  3VDA A;  1QAK A;  4BZF A;  2WW2 A;  1QX1 A;  1GXN A;  1MZC B;  3H2W A;  4GTT B;  1TXK A;  2FBA A;  3PYA A;  4LNB B;  1FBW A;  4LNG B;  3SDU A;  3DST B;  3WIQ A;  5FO7 B;  4D4D A;  3WIW A;  3MUZ 1;  1O1S B;  1N4S B;  2C11 A;  2V8J A;  3EJQ A;  3BLB A;  1TNY B;  2WZS A;  1HM2 A;  1YQ2 A;  1K1X A;  3QFY A;  1OJP A;  4D6F A;  1NKG A;  3E33 B;  4D71 A;  1W4N A;  3WVF A;  3IAP A;  3X3X A;  5IK0 A;  3RJ3 A;  5C05 A;  1KSD A;  1O79 A;  2WVY A;  3VD7 A;  3RSY A;  1K72 A;  2RI9 A;  4GTR B;  3MV0 1;  1JZ6 A;  2F1B A;  3PMM A;  1JRQ A;  2PNC A;  1FO3 A;  2BB5 A;  1HXC A;  1KFG A;  1X1J A;  1O1R B;  4FUS A;  2V8K A;  2F7P A;  1YGA A;  2I07 B;  2B4F A;  2XN2 A;  1HM3 A;  2ZIS B;  3T2P A;  4D72 A;  4RNQ A;  1NSZ A;  1MN0 A;  2W0Q A;  5DGR A;  1V5C A;  4GTV B;  3NFV A;  1UG9 A;  3DX0 A;  4F10 A;  1FBO A;  5IL8 A;  4BTY A;  5DHK A;  1IA6 A;  2CQS A;  2WDA A;  3N9H A;  1W6C A;  2H6F B;  3UD1 A;  2BB6 A;  1TN7 B;  1IVV A;  2E24 A;  2KXS A;  1NS4 A;  2FV0 A;  2J5C A;  3MI6 A;  4KKI A;  1D6Y A;  3K25 A;  3QG0 A;  3WFA A;  1PX3 A;  3PZ3 B;  2WYN A;  4V1S A;  2Y74 A;  2ZXQ A;  1QBQ B;  3K11 A;  4EHM B;  4LNV A;  1NSM A;  2WW0 A;  3M7B A;  1JCR B;  1KRF A;  1N20 A;  1IQX A;  4DLQ A;  1O6R A;  1SQC A;  3EJT A;  3M75 A;  4KKJ A;  3HIG A;  1TU5 A;  4GTM B;  1HXA A;  3LZ9 A;  3WKI A;  3VW5 A;  3WA2 X;  4C1S A;  4GTP B;  4GTO B;  4TXT A;  2EAE A;  2CQT A;  2XQW A;  3Q73 B;  1N24 A;  4QT9 A;  1XWQ A;  1TN6 B;  3MUY 1;  3K7X A;  1HMW A;  2CIS A;  4FNP A;  1ULV A;  3E73 A;  3CIH A;  3EZ8 A;  4GL3 A;  3SFY B;  4M76 A; 
#chains in the Genus database with same CATH homology
 1I8Q A;  1MMX A;  2FUT A;  3DEC A;  2Q1F A;  3T0D A;  1N7R A;  1JOV A;  5A1A A;  3DYP A;  4OJZ A;  2WVZ A;  1JYW A;  3VD9 A;  3IAQ A;  1N7O A;  1RWA A;  3NJX A;  4BZH A;  1LF6 A;  1OJO A;  2X03 A;  3I3E A;  1Z45 A;  1NSX A;  1F9G A;  1JZ8 A;  1C82 A;  4OK2 A;  1MMZ A;  1NS7 A;  3T08 A;  3E7J A;  1JZ3 A;  1NS8 A;  4D6E A;  1RWH A;  1N7N A;  1RWC A;  1NSS A;  4D6G A;  2CIR A;  1JZ5 A;  1RW9 A;  2JKE A;  1L7K A;  1NSV A;  2BRW A;  1F4A A;  3I3D A;  1MMU A;  2JKP A;  3TY1 A;  4NEI A;  3A0O A;  2WMI B;  1N7P A;  1HN1 A;  2WMI A;  2WW3 A;  1LF9 A;  1OJN A;  1W3Y A;  1SNZ A;  1F1S A;  2CIQ A;  1JYX A;  1QAZ A;  3J7H A;  2WW1 A;  3IMH A;  3VDA A;  4BZF A;  1J0N A;  1F4H A;  2WW2 A;  3MV1 1;  1TXK A;  1RWF A;  4TTG A;  4OK4 A;  4D6H A;  3VDC A;  4E1Y A;  3VD3 A;  2WMK A;  2BRP A;  1K1Y A;  1NS0 A;  1SO0 A;  1PX4 A;  3MUZ 1;  3T0A A;  1JYN A;  4D6C A;  3DYO A;  3OB8 A;  3AFL A;  4MMI A;  2WZS A;  1NS2 A;  1HM2 A;  1YQ2 A;  3VSM A;  3NJV A;  2WMH A;  3NRE A;  1K1X A;  2WMG A;  4DUX A;  3DYM A;  1OJP A;  5JMF A;  4D6F A;  1NKG A;  4D71 A;  2WVX B;  3WVF A;  3IAP A;  2WVX A;  3NNB A;  4D6I A;  4J5T A;  2JKA A;  1EGU A;  2WVY A;  4RNL A;  3VD7 A;  3MV0 1;  1JZ6 A;  3BGA A;  1HV6 A;  1X1H A;  3Q1N A;  1HN0 A;  1X1I A;  3VD4 A;  4D6J A;  2ZQ0 A;  1JZ4 A;  3CZJ A;  1X1J A;  3OS7 A;  1HMU A;  2XHN A;  3VD5 A;  3A24 A;  1YGA A;  2HTA A;  3BLC A;  1HM3 A;  1OJM A;  3E80 A;  1RWG A;  2D73 A;  3I3B A;  4D72 A;  3T2P A;  1NSZ A;  1MN0 A;  4BZE A;  3T0B A;  3BS6 A;  3ECQ A;  3NFV A;  1UG9 A;  1LXK A;  3SEP A;  1N7Q A;  4F10 A;  1LUR A;  5E1Q A;  1MMY A;  4D6D A;  2BRV X;  2WMF A;  2FUQ A;  4F13 A;  1LOH A;  4DUW A;  1NSU A;  3MWX A;  2WDA A;  4BZG A;  3VDB A;  3VSN A;  2E24 A;  4MMH A;  1NS4 A;  2WCO A;  5JMD A;  1NSR A;  3K25 A;  3WFA A;  1PX3 A;  1CB8 A;  4FNV A;  2WMJ A;  2ZXQ A;  1JZ2 A;  3T2Q A;  2HTB A;  1NSM A;  2WW0 A;  2E22 A;  1J0M A;  4OZW A;  1DP0 A;  3OBA A;  1L7J A;  3T09 A;  4AQ0 A;  1LXM A;  1K1W A;  4OZV A;  2XSG A;  3MUY 1;  1HMW A;  2CIS A;  1ULV A;  3E1F 1;  4DUV A;  1JZ7 A;  1JYV A;  3T2O A;  3DCD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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