2WCOA

Structures of the streptomyces coelicolor a3(2) hyaluronan lyase in complex with oligosaccharide substrates and an inhibitor
Total Genus 263
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
263
sequence length
742
structure length
742
Chain Sequence
ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Lyase
molecule keywords PUTATIVE SECRETED LYASE
publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces coelicolor a3(2)
total genus 263
structure length 742
sequence length 742
ec nomenclature
pdb deposition date 2009-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2wcoA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2wcoA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2wcoA02
1MMYA 1HM2A 5A1AA 3VD9A 1LF9A 3T2PA 4MMHA 3VD4A 4BZEA 1X1JA 5JMDA 3MV11 1OJOA 1NSVA 4D6DA 3NREA 2WW1A 1N7PA 2CIRA 4BZGA 4D6IA 1Z45A 2WMFA 3BGAA 2WMGA 1NS2A 1JZ5A 2CISA 1C82A 3OB8A 3VDAA 1MMXA 2BRVX 1K1WA 1J0NA 1NS4A 3DYOA 3E7JA 2FUTA 4F10A 1NSRA 1F1SA 1JZ2A 3VSNA 2WMIB 4D6FA 3MUY1 2WW2A 2WW0A 1NS0A 1LXMA 2BRPA 2WCOA 3MV01 4DUVA 4TTGA 3DECA 1NS8A 3I3BA 1NS7A 1SNZA 3T0AA 2WMJA 1NSXA 2WMKA 3OBAA 2FUQA 1OJNA 3A0OA 1JZ6A 4AQ0A 1JZ7A 1CB8A 2X03A 3T0BA 2JKAA 4D6HA 3E1F1 2HTBA 3MWXA 5E1QA 1HMUA 4D6EA 1HMWA 3DYPA 2BRWA 3MUZ1 1JYXA 1RWHA 4D6GA 3DCDA 3T09A 1PX3A 1UG9A 3VD5A 3CZJA 1L7KA 2WW3A 1PX4A 1HM3A 2WVXA 2XSGA 3DYMA 1MMZA 3A24A 2WMHA 1JYWA 1N7RA 3IAQA 1DP0A 1LURA 3AFLA 1HN1A 1NSUA 2WZSA 1SO0A 3K25A 3I3DA 1HN0A 5JMFA 4RNLA 2JKEA 1JOVA 2ZXQA 1JZ8A 1HV6A 3T2OA 1OJPA 1RWAA 1RWCA 1RWGA 3VSMA 1NSZA 2E24A 4D6JA 1NSMA 3NNBA 2E22A 3E80A 3NJVA 1JYNA 3T0DA 1MMUA 1YGAA 1L7JA 4F13A 1TXKA 4D71A 4FNVA 1K1YA 1NKGA 4DUWA 3ECQA 1X1HA 4NEIA 1JZ4A 3J7HA 1F9GA 1YQ2A 1JYVA 1RWFA 4OK2A 1JZ3A 3IAPA 3SEPA 3VD3A 1LF6A 2JKPA 3VDCA 1MN0A 3T2QA 1N7QA 1N7NA 1F4HA 4OZWA 2WVZA 1J0MA 3VD7A 1X1IA 1QAZA 4OJZA 1RW9A 2WMIA 2D73A 1W3YA 1ULVA 3NJXA 4DUXA 3T08A 1EGUA 2ZQ0A 1N7OA 2WVXB 3I3EA 3IMHA 1LOHA 2WVYA 2XHNA 3OS7A 4BZHA 3Q1NA 1NSSA 3WFAA 1LXKA 1I8QA 2WDAA 3NFVA 2Q1FA 4OZVA 3VDBA 2CIQA 1F4AA 2HTAA 4E1YA 1K1XA 4MMIA 4OK4A 4D6CA 1OJMA 4BZFA 4D72A
chains in the Genus database with same CATH superfamily
3DX3A 3VD9A 1DL2A 3E30B 3E34B 5EASA 3EJRA 4FNRA 3VD4A 1N24A 5C05A 4LNBB 1IA7A 2PNCA 3TF4A 2CIRA 4L6XA 3HI7A 2FYVA 4D6IA 1Z45A 4ZRPA 3WIRA 3W7WA 1JZ5A 1AGMA 1C82A 3OB8A 1R34A 1R33A 3SXXA 3M77A 3M78A 2WYHA 1J0NA 2B4FA 3QFYA 1JZ2A 1F1SA 3G6JB 3F59A 4AYQA 3VSNA 1US1A 3WKIA 1QWUA 3NBJA 3RX7A 1QQFA 1GSZA 1SQCA 1NS0A 1LXMA 2WCOA 1L2AA 1IQYA 3BUPA 3I3BA 1NS8A 3X3YA 3T0AA 1N4RB 4CJ1A 2ZISB 1WZZA 3BVTA 1OJNA 3DSTB 1KWFA 1WU4A 1N22A 1TNBB 1MZCB 1N20A 2PN5A 3D51A 3X42A 5ILYA 1TN6B 2ZBLA 1HXGA 4KTPA 1TQTA 1GXOA 1DOGA 3E1F1 2V8IA 3DYPA 4BOJA 3KQ4A 1G9JA 1N4SB 4D6GA 3T09A 1UG9A 3VD5A 3AMOB 2RI8A 1L7KA 3WKHA 4AYPA 4D8OA 3DX0A 1O5MB 3ANKA 2WINB 2H6FB 5FOBB 4GTOB 4FNSA 4FXKB 3KLSA 1HN1A 2J5CA 2CFLA 4D1JA 4DLOA 3M76A 2CG1A 4DLQA 3BVWA 3VXDA 4D4DA 1WMOA 1GHQA 2E24A 3DDGA 3MPHA 3BLBA 1TU5A 3NNBA 3Q78B 3S4BA 3NJVA 2BEDB 1TNUB 3EJSA 4F13A 3P5RA 4FNVA 1FBOA 5GY3A 1GAHA 4NEIA 1W4NA 1JZ4A 3M7CA 1F9GA 1YQ2A 2F1AA 2RDYA 5M7YA 1RWFA 4YDEB 2F0YB 1SIHA 1CLCA 3VD3A 5DHIA 1H39A 1H14A 1W6CA 1MN0A 3EJTA 1RKYA 1HTYA 2A8ZA 3EUVB 4L0GA 3AFJA 2KXRA 1KZOB 1X1IA 5IK6A 5FO9B 1N23A 3LVTA 1ULVA 2P0VA 3RJ3A 1DYUA 1EGUA 2ZQ0A 4KFEA 3X40A 5FO8B 1V5CA 4ZG8A 2FUZA 1RJOA 2YFOA 3M7LA 3BUIA 4CE7A 1FO3A 3P5PA 4MU9A 1AVKA 5IL3A 3E73A 4ZRQA 2VN7A 1AV4A 1KREA 4BZHA 3WFAA 3W7UA 4GTRB 2Q1FA 4LNVA 3HXEB 3E33B 4BOKA 4E1YA 1TQSA 1W6KA 3RX5A 2JJBA 2JF4A 3DSXB 4D6CA 2F6DA 4EHMB 2OQEC 2ALWA 1QSJA 3QT9A 1L7JA 5CZLA 5ILKA 3U7VA 4BTWA 2FV0A 3T2PA 3AMOA 3QXFA 3GT5A 2WYIA 5JMDA 1OJOA 3X3XA 1TN7B 2AFAA 3PQIA 5IK0A 2WMFA 5JPNB 4ZH5A 5IM1A 1NS2A 2EACA 2OW7A 4QT9A 5IL8A 1NS4A 1LD7B 3D52A 2ZIRB 1O6QA 1EKMA 1NSRA 2WMIB 1L1YA 4D6FA 4AYRA 3G4FA 2WW2A 2Y73A 4Z4LA 1H13A 3SAEA 3Q75B 4TTGA 3N9HA 1NSXA 1JZ6A 1O6RA 2GZ6A 1JZ7A 3EU5B 2CWVA 1NXCA 3Q7FB 1QWNA 2YIKA 2JG0A 2WO0A 3T0BA 2JKAA 3WA3A 1JCRB 2V3PA 4TF4A 1HMUA 4ZH1A 4D94A 4D6EA 1HMWA 2BRWA 1FO2A 3MUZ1 1WMNA 3DCDA 3S4CA 4GAXA 2PMVA 4YDOB 1D6ZA 2QNOA 3DSUB 1HX9A 1IQXA 2XN1A 2F7OA 3D50A 1HM3A 1TNOB 1VD5A 3W7SA 3QWTA 1MMZA 2F7QA 4K3AA 4GTVB 4GTMB 3D5SA 2WMHA 1JYWA 5AGDA 3ANIA 1X81B 1TQWA 3AFLA 2WZSA 2D5JA 3WVFA 2EABA 3K5TA 2B39A 3Q7AB 3K25A 1W6GA 2WY8A 1KRFA 4RNLA 3HIGA 2ZXQA 2WW0A 2E2VA 1HV6A 3M02A 4YCRA 4XUVA 3X41A 1RWAA 1NSZA 1H36A 2Z07A 2V3NA 3DSVB 1JCSB 2E22A 3RX8A 2OQEA 2CFGA 1XW2A 3HXDB 2ONGA 1KSCA 3H7LA 1TXKA 1H3AA 4V1SA 4DUWA 3QRYA 1V7XA 1IS9A 5IK9A 3T33A 1QAFA 4FNQA 2XN2A 4OK2A 1FPPB 1WU5A 1LTXB 1FCEA 1LF6A 3PZ1B 2JKPA 2YX9A 3T2QA 1N7QA 3QDEA 2VN4A 2WOFA 3E32B 3DPYB 3SFXB 1KKTA 3VD7A 3WIQA 1QAZA 3CZSA 2D1WA 5EAUA 4D1IA 1FT2B 4KKJA 3DX2A 2WMIA 1W3YA 3NJXA 3M00A 3SFYB 4DUXA 3T08A 4FXGB 3RENA 3X17A 3DRAB 1O1RB 2WVXB 1HXAA 3WIWA 2WGQA 3I3EA 3BUQA 3K11A 2DRQA 3DSSB 1LOHA 2GOXA 1N4PB 3PYBA 2CFKA 3HXBB 5E2JA 1UT9A 1V7VA 1V5DA 1NSSA 1QBQB 1G9GA 3KBUC 3VDBA 1KS8A 1GA2A 1JS4A 3N0GA 3KN4A 1QX1A 4EV2A 3UD2A 1IVUA 1NI1B 4OK4A 1PU4A 1RQ5A 1OJMA 2XWJB 2CFWA 4BTYA 3S9VA 1MMYA 3M01A 1FMIA 1H3CA 1LF9A 3W5NA 1N1BA 3PYAA 1SA5B 2CQSA 3ON6A 1SA4B 3MV11 3NREA 1H37A 1H54A 5ILDA 4FJQA 1FP3A 1N7PA 1D6UA 2H6GB 3QPFA 2ZZRA 3KSLB 2FBAA 3BGAA 1LD8B 4KTRA 2WMGA 2CISA 3BVUA 4J5TA 3VDAA 4LNGB 2F1BA 3DYOA 3E7JA 2FUTA 3DX1A 3BUBA 3X3ZA 3SDUA 2A73B 2C11A 4GTQB 3P2CA 1W6JA 1PS3A 3M73A 4FUSA 5ILJA 1KSDA 3MUY1 2H6IB 3ALAA 3HXFB 3LZ9A 1N4QB 3DECA 1SNZA 2WMJA 1LVNA 1W2ZA 3OXUA 2D8LA 2WMKA 4ONTA 3EJUA 2FUQA 2H6HB 3A0OA 1GXMA 4JJJA 4AQ0A 3RRSA 4FNUA 5FO7B 3BVVA 2X03A 5KBPA 1IVWA 3ANJA 1HXCA 2DROA 5MEHA 2F18A 2HTBA 3MWXA 5E1QA 3DDFA 3D3IA 4D4BA 1JYXA 3M7EA 3DSWB 1RWHA 1KFGA 1HZFA 1PX3A 3CZJA 1KSIA 1N1ZA 3SDRA 3ACSA 2WVXA 1DCEB 1UI8A 1S63B 2XSGA 2DRRA 3T0UA 2XWBB 1N7RA 3IAQA 3W7XA 1DP0A 5GZKA 4D4CA 1SO0A 1HN0A 2JKEA 1F9OA 1JOVA 3CU7A 2I07B 2SQCA 3SDQA 5JPMB 1CEMA 1QALA 1OJPA 1RWGA 1TF4A 3VSMA 2CFDA 2C10A 4K35A 5IKHA 1GAIA 3T0DA 4GL3A 4GTTB 3RSYA 3PZ3B 5EATA 4LIXA 4Z4JA 2ONHA 1NKGA 4GTPB 1V7WA 2OW6A 3LOYA 1N21A 2XN0A 3BUDA 2NOJA 1WU6A 1NC5A 4WVBA 3SDTA 2BBCA 2OKXA 3PZ4B 3IAPA 3SEPA 3VDCA 3M74A 1N7NA 1N9EA 3C72B 2WVZA 2KXSA 1J0MA 5ILHA 4OJZA 2G02A 1N94B 4AYOA 1C3DA 1NL4B 2WOHA 2V8KA 4KFDA 2D73A 1IU7A 4CJ0A 3CV5A 3M71A 5IKAA 1N7OA 4KKIA 3IMHA 1A2VA 3D4YA 3Q79B 3VW5A 1O79A 3MI6A 3EJQA 3OS7A 3Q1NA 2WDAA 1I8QA 1R76A 2W0QA 1QAKA 3HIIA 2HTAA 1TNYB 1O6HA 3WUXA 4MMIA 2Y74A 3E6UA 4MBGB 3H2WA 3UD1A 4UFCA 4BZFA 1HM2A 5A1AA 3PGBA 3G4DA 3DX4A 4DOEA 2NVPA 2F7RA 4MMHA 4BZEA 1X1JA 3HXCB 2BT3A 4WVCA 1NSVA 1D8EB 4D6DA 2CWUA 2WW1A 1TN8B 2E2UA 4BZGA 1K72A 2WY7A 2BB5A 1TQVA 1H12A 2BB6A 3QG0A 3CZNA 3S4DA 3M75A 2OOVC 3WA2X 1JCQB 2ZL8A 1MMXA 3EZ8A 1D6YA 2BRVX 4V1RA 1D8DB 1IVVA 3D4ZA 1K1WA 3QT3A 1H35A 4F10A 1F9DA 3EU8A 5ILZA 1SPUA 1N9AB 1GXNA 3GZKA 3GLYA 1IA6A 1FT1B 3H3KA 1FBWA 4M76A 5DGQA 3N0FA 3SDVA 2GH4A 1AYXA 4EL8A 2R2LB 2BRPA 3E37B 2XFGA 1HWWA 3MV01 4DUVA 1HXKA 3M7BA 3NBBA 4FNPA 3WKFA 1OACA 1NS7A 5DHKA 4KFFA 2YFNA 2XQWA 3OBAA 3EJPA 3ACTA 1S64B 1CB8A 4Q88A 1GLMA 4DI5A 4D6HA 4TXTA 2IEJB 1AVLA 3KSQB 1TQUA 1WMPA 3SX1A 2CQTA 2WW3A 1PX4A 3BS6A 3DYMA 4DODA 3A24A 1G87A 4D4AA 1HCUA 1LURA 1NSUA 1H3BA 3QXQA 1N95B 2CG0A 3I3DA 5JMFA 1O1SB 3CIHA 2EAEA 1JZ8A 3T2OA 3TY1A 1RWCA 2V8JA 1JRQA 2F7PA 1XWQA 4D6JA 1XWTA 1NSMA 3E80A 1W7CA 4RNQA 3A3VA 1JYNA 3PMMA 5CD2A 1MMUA 4WU0A 1YGAA 3KBTC 3W7TA 4Q2BA 2DRSA 4D71A 1K1YA 1O1TB 3ECQA 3K7XA 1X1HA 1W5ZA 1FAEA 3J7HA 4FNTA 3QR8A 1UI7A 1JYVA 1X9DA 3WC3A 3PZ2B 3QSPA 1O7DD 3KIIA 1JZ3A 4EV5A 2FV1A 3EQAA 2AHFA 2G0DA 2OOVA 2AHGA 4GTSB 1F4HA 3BLCA 4OZWA 3W5MA 5CA3A 3M72A 5M7IA 2CWTA 1RW9A 3Q73B 2RI9A 4WVAA 2WIIB 3QFZA 4L9PB 5KKBA 1TNZB 3D5RA 5DGRA 2WYNA 5GW7A 2WVYA 3S4AA 2XHNA 2EADA 1LXKA 3NFVA 4OZVA 5ILIA 4BTXA 2E2TA 2RGKA 3SQCA 1UMPA 2CIQA 1G6IA 1F4AA 1KZPB 4C1SA 1K1XA 3WKGA 3BVXA 1IVXA 1SIIA 3OEDA 4D72A
chains in the Genus database with same CATH topology
1MMYA 1HM2A 5A1AA 3VD9A 1LF9A 3T2PA 4MMHA 3VD4A 4BZEA 1X1JA 5JMDA 3MV11 1OJOA 1NSVA 4D6DA 3NREA 2WW1A 1N7PA 2CIRA 4BZGA 4D6IA 1Z45A 2WMFA 3BGAA 2WMGA 1NS2A 1JZ5A 2CISA 1C82A 3OB8A 4J5TA 1MMXA 3VDAA 2BRVX 1K1WA 1J0NA 1NS4A 3DYOA 3E7JA 2FUTA 4F10A 1NSRA 1F1SA 1JZ2A 3VSNA 2WMIB 4D6FA 3MUY1 2WW2A 2WW0A 1NS0A 1LXMA 2BRPA 2WCOA 3MV01 4DUVA 4TTGA 3DECA 1NS8A 3I3BA 1NS7A 1SNZA 3T0AA 2WMJA 1NSXA 2WMKA 3OBAA 2FUQA 1OJNA 3A0OA 1JZ6A 4AQ0A 1JZ7A 1CB8A 2X03A 3T0BA 2JKAA 4D6HA 3E1F1 2HTBA 3MWXA 5E1QA 1HMUA 4D6EA 1HMWA 3DYPA 2BRWA 3MUZ1 1JYXA 1RWHA 4D6GA 3DCDA 3T09A 1PX3A 1UG9A 3VD5A 3CZJA 1L7KA 2WW3A 1PX4A 1HM3A 2WVXA 3BS6A 2XSGA 3DYMA 1MMZA 3A24A 2WMHA 1JYWA 1N7RA 3IAQA 1DP0A 1LURA 3AFLA 1HN1A 1NSUA 2WZSA 3WVFA 1SO0A 3K25A 3I3DA 1HN0A 5JMFA 4RNLA 2JKEA 1JOVA 2ZXQA 1JZ8A 1HV6A 3T2OA 3TY1A 1OJPA 1RWAA 1RWCA 1RWGA 3VSMA 1NSZA 2E24A 4D6JA 1NSMA 3NNBA 2E22A 3E80A 3NJVA 1JYNA 3T0DA 1MMUA 1YGAA 1L7JA 4F13A 1TXKA 4D71A 4FNVA 1K1YA 1NKGA 4DUWA 3ECQA 1X1HA 4NEIA 1JZ4A 3J7HA 1F9GA 1YQ2A 1JYVA 1RWFA 4OK2A 1JZ3A 3IAPA 3SEPA 3VD3A 1LF6A 2JKPA 3VDCA 1MN0A 3T2QA 1N7QA 1N7NA 1F4HA 3BLCA 4OZWA 2WVZA 1J0MA 3VD7A 1X1IA 1QAZA 4OJZA 1RW9A 2WMIA 2D73A 1W3YA 1ULVA 3NJXA 4DUXA 3T08A 1EGUA 2ZQ0A 1N7OA 2WVXB 3I3EA 3IMHA 1LOHA 2WVYA 2XHNA 3OS7A 4BZHA 3Q1NA 1NSSA 3WFAA 1LXKA 1I8QA 2WDAA 3NFVA 2Q1FA 4OZVA 3VDBA 2CIQA 1F4AA 2HTAA 4E1YA 1K1XA 4MMIA 4OK4A 4D6CA 1OJMA 4BZFA 4D72A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MMY A;  1HM2 A;  5A1A A;  3VD9 A;  1LF9 A;  3T2P A;  4MMH A;  3VD4 A;  4BZE A;  1X1J A;  5JMD A;  3MV1 1;  1OJO A;  1NSV A;  4D6D A;  3NRE A;  2WW1 A;  1N7P A;  2CIR A;  4BZG A;  4D6I A;  1Z45 A;  2WMF A;  3BGA A;  2WMG A;  1NS2 A;  1JZ5 A;  2CIS A;  1C82 A;  3OB8 A;  3VDA A;  1MMX A;  2BRV X;  1K1W A;  1J0N A;  1NS4 A;  3DYO A;  3E7J A;  2FUT A;  4F10 A;  1NSR A;  1F1S A;  1JZ2 A;  3VSN A;  2WMI B;  4D6F A;  3MUY 1;  2WW2 A;  2WW0 A;  1NS0 A;  1LXM A;  2BRP A;  2WCO A;  3MV0 1;  4DUV A;  4TTG A;  3DEC A;  1NS8 A;  3I3B A;  1NS7 A;  1SNZ A;  3T0A A;  2WMJ A;  1NSX A;  2WMK A;  3OBA A;  2FUQ A;  1OJN A;  3A0O A;  1JZ6 A;  4AQ0 A;  1JZ7 A;  1CB8 A;  2X03 A;  3T0B A;  2JKA A;  4D6H A;  3E1F 1;  2HTB A;  3MWX A;  5E1Q A;  1HMU A;  4D6E A;  1HMW A;  3DYP A;  2BRW A;  3MUZ 1;  1JYX A;  1RWH A;  4D6G A;  3DCD A;  3T09 A;  1PX3 A;  1UG9 A;  3VD5 A;  3CZJ A;  1L7K A;  2WW3 A;  1PX4 A;  1HM3 A;  2WVX A;  2XSG A;  3DYM A;  1MMZ A;  3A24 A;  2WMH A;  1JYW A;  1N7R A;  3IAQ A;  1DP0 A;  1LUR A;  3AFL A;  1HN1 A;  1NSU A;  2WZS A;  1SO0 A;  3K25 A;  3I3D A;  1HN0 A;  5JMF A;  4RNL A;  2JKE A;  1JOV A;  2ZXQ A;  1JZ8 A;  1HV6 A;  3T2O A;  1OJP A;  1RWA A;  1RWC A;  1RWG A;  3VSM A;  1NSZ A;  2E24 A;  4D6J A;  1NSM A;  3NNB A;  2E22 A;  3E80 A;  3NJV A;  1JYN A;  3T0D A;  1MMU A;  1YGA A;  1L7J A;  4F13 A;  1TXK A;  4D71 A;  4FNV A;  1K1Y A;  1NKG A;  4DUW A;  3ECQ A;  1X1H A;  4NEI A;  1JZ4 A;  3J7H A;  1F9G A;  1YQ2 A;  1JYV A;  1RWF A;  4OK2 A;  1JZ3 A;  3IAP A;  3SEP A;  3VD3 A;  1LF6 A;  2JKP A;  3VDC A;  1MN0 A;  3T2Q A;  1N7Q A;  1N7N A;  1F4H A;  4OZW A;  2WVZ A;  1J0M A;  3VD7 A;  1X1I A;  1QAZ A;  4OJZ A;  1RW9 A;  2WMI A;  2D73 A;  1W3Y A;  1ULV A;  3NJX A;  4DUX A;  3T08 A;  1EGU A;  2ZQ0 A;  1N7O A;  2WVX B;  3I3E A;  3IMH A;  1LOH A;  2WVY A;  2XHN A;  3OS7 A;  4BZH A;  3Q1N A;  1NSS A;  3WFA A;  1LXK A;  1I8Q A;  2WDA A;  3NFV A;  2Q1F A;  4OZV A;  3VDB A;  2CIQ A;  1F4A A;  2HTA A;  4E1Y A;  1K1X A;  4MMI A;  4OK4 A;  4D6C A;  1OJM A;  4BZF A;  4D72 A; 
#chains in the Genus database with same CATH topology
 3DX3 A;  3VD9 A;  1DL2 A;  3E30 B;  3E34 B;  5EAS A;  3EJR A;  4FNR A;  3VD4 A;  1N24 A;  5C05 A;  4LNB B;  1IA7 A;  2PNC A;  3TF4 A;  2CIR A;  4L6X A;  3HI7 A;  2FYV A;  4D6I A;  1Z45 A;  4ZRP A;  3WIR A;  3W7W A;  1JZ5 A;  1AGM A;  1C82 A;  3OB8 A;  1R34 A;  1R33 A;  3SXX A;  3M77 A;  3M78 A;  2WYH A;  1J0N A;  2B4F A;  3QFY A;  1JZ2 A;  1F1S A;  3G6J B;  3F59 A;  4AYQ A;  3VSN A;  1US1 A;  3WKI A;  1QWU A;  3NBJ A;  3RX7 A;  1QQF A;  1GSZ A;  1SQC A;  1NS0 A;  1LXM A;  2WCO A;  1L2A A;  1IQY A;  3BUP A;  3I3B A;  1NS8 A;  3X3Y A;  3T0A A;  1N4R B;  4CJ1 A;  2ZIS B;  1WZZ A;  3BVT A;  1OJN A;  3DST B;  1KWF A;  1WU4 A;  1N22 A;  1TNB B;  1MZC B;  1N20 A;  2PN5 A;  3D51 A;  3X42 A;  5ILY A;  1TN6 B;  2ZBL A;  1HXG A;  4KTP A;  1TQT A;  1GXO A;  1DOG A;  3E1F 1;  2V8I A;  3DYP A;  4BOJ A;  3KQ4 A;  1G9J A;  1N4S B;  4D6G A;  3T09 A;  1UG9 A;  3VD5 A;  3AMO B;  2RI8 A;  1L7K A;  3WKH A;  4AYP A;  4D8O A;  3DX0 A;  1O5M B;  3ANK A;  2WIN B;  2H6F B;  5FOB B;  4GTO B;  4FNS A;  4FXK B;  3KLS A;  1HN1 A;  2J5C A;  2CFL A;  4D1J A;  4DLO A;  3M76 A;  2CG1 A;  4DLQ A;  3BVW A;  3VXD A;  4D4D A;  1WMO A;  1GHQ A;  2E24 A;  3DDG A;  3MPH A;  3BLB A;  1TU5 A;  3NNB A;  3Q78 B;  3S4B A;  3NJV A;  2BED B;  1TNU B;  3EJS A;  4F13 A;  3P5R A;  4FNV A;  1FBO A;  5GY3 A;  1GAH A;  4NEI A;  1W4N A;  1JZ4 A;  3M7C A;  1F9G A;  1YQ2 A;  2F1A A;  2RDY A;  5M7Y A;  1RWF A;  4YDE B;  2F0Y B;  1SIH A;  1CLC A;  3VD3 A;  5DHI A;  1H39 A;  1H14 A;  1W6C A;  1MN0 A;  3EJT A;  1RKY A;  1HTY A;  2A8Z A;  3EUV B;  4L0G A;  3AFJ A;  2KXR A;  1KZO B;  1X1I A;  5IK6 A;  5FO9 B;  1N23 A;  3LVT A;  1ULV A;  2P0V A;  3RJ3 A;  1DYU A;  1EGU A;  2ZQ0 A;  4KFE A;  3X40 A;  5FO8 B;  1V5C A;  4ZG8 A;  2FUZ A;  1RJO A;  2YFO A;  3M7L A;  3BUI A;  4CE7 A;  1FO3 A;  3P5P A;  4MU9 A;  1AVK A;  5IL3 A;  3E73 A;  4ZRQ A;  2VN7 A;  1AV4 A;  1KRE A;  4BZH A;  3WFA A;  3W7U A;  4GTR B;  2Q1F A;  4LNV A;  3HXE B;  3E33 B;  4BOK A;  4E1Y A;  1TQS A;  1W6K A;  3RX5 A;  2JJB A;  2JF4 A;  3DSX B;  4D6C A;  2F6D A;  4EHM B;  2OQE C;  2ALW A;  1QSJ A;  3QT9 A;  1L7J A;  5CZL A;  5ILK A;  3U7V A;  4BTW A;  2FV0 A;  3T2P A;  3AMO A;  3QXF A;  3GT5 A;  2WYI A;  5JMD A;  1OJO A;  3X3X A;  1TN7 B;  2AFA A;  3PQI A;  5IK0 A;  2WMF A;  5JPN B;  4ZH5 A;  5IM1 A;  1NS2 A;  2EAC A;  2OW7 A;  4QT9 A;  5IL8 A;  1NS4 A;  1LD7 B;  3D52 A;  2ZIR B;  1O6Q A;  1EKM A;  1NSR A;  2WMI B;  1L1Y A;  4D6F A;  4AYR A;  3G4F A;  2WW2 A;  2Y73 A;  4Z4L A;  1H13 A;  3SAE A;  3Q75 B;  4TTG A;  3N9H A;  1NSX A;  1JZ6 A;  1O6R A;  2GZ6 A;  1JZ7 A;  3EU5 B;  2CWV A;  1NXC A;  3Q7F B;  1QWN A;  2YIK A;  2JG0 A;  2WO0 A;  3T0B A;  2JKA A;  3WA3 A;  1JCR B;  2V3P A;  4TF4 A;  1HMU A;  4ZH1 A;  4D94 A;  4D6E A;  1HMW A;  2BRW A;  1FO2 A;  3MUZ 1;  1WMN A;  3DCD A;  3S4C A;  4GAX A;  2PMV A;  4YDO B;  1D6Z A;  2QNO A;  3DSU B;  1HX9 A;  1IQX A;  2XN1 A;  2F7O A;  3D50 A;  1HM3 A;  1TNO B;  1VD5 A;  3W7S A;  3QWT A;  1MMZ A;  2F7Q A;  4K3A A;  4GTV B;  4GTM B;  3D5S A;  2WMH A;  1JYW A;  5AGD A;  3ANI A;  1X81 B;  1TQW A;  3AFL A;  2WZS A;  2D5J A;  3WVF A;  2EAB A;  3K5T A;  2B39 A;  3Q7A B;  3K25 A;  1W6G A;  2WY8 A;  1KRF A;  4RNL A;  3HIG A;  2ZXQ A;  2WW0 A;  2E2V A;  1HV6 A;  3M02 A;  4YCR A;  4XUV A;  3X41 A;  1RWA A;  1NSZ A;  1H36 A;  2Z07 A;  2V3N A;  3DSV B;  1JCS B;  2E22 A;  3RX8 A;  2OQE A;  2CFG A;  1XW2 A;  3HXD B;  2ONG A;  1KSC A;  3H7L A;  1TXK A;  1H3A A;  4V1S A;  4DUW A;  3QRY A;  1V7X A;  1IS9 A;  5IK9 A;  3T33 A;  1QAF A;  4FNQ A;  2XN2 A;  4OK2 A;  1FPP B;  1WU5 A;  1LTX B;  1FCE A;  1LF6 A;  3PZ1 B;  2JKP A;  2YX9 A;  3T2Q A;  1N7Q A;  3QDE A;  2VN4 A;  2WOF A;  3E32 B;  3DPY B;  3SFX B;  1KKT A;  3VD7 A;  3WIQ A;  1QAZ A;  3CZS A;  2D1W A;  5EAU A;  4D1I A;  1FT2 B;  4KKJ A;  3DX2 A;  2WMI A;  1W3Y A;  3NJX A;  3M00 A;  3SFY B;  4DUX A;  3T08 A;  4FXG B;  3REN A;  3X17 A;  3DRA B;  1O1R B;  2WVX B;  1HXA A;  3WIW A;  2WGQ A;  3I3E A;  3BUQ A;  3K11 A;  2DRQ A;  3DSS B;  1LOH A;  2GOX A;  1N4P B;  3PYB A;  2CFK A;  3HXB B;  5E2J A;  1UT9 A;  1V7V A;  1V5D A;  1NSS A;  1QBQ B;  1G9G A;  3KBU C;  3VDB A;  1KS8 A;  1GA2 A;  1JS4 A;  3N0G A;  3KN4 A;  1QX1 A;  4EV2 A;  3UD2 A;  1IVU A;  1NI1 B;  4OK4 A;  1PU4 A;  1RQ5 A;  1OJM A;  2XWJ B;  2CFW A;  4BTY A;  3S9V A;  1MMY A;  3M01 A;  1FMI A;  1H3C A;  1LF9 A;  3W5N A;  1N1B A;  3PYA A;  1SA5 B;  2CQS A;  3ON6 A;  1SA4 B;  3MV1 1;  3NRE A;  1H37 A;  1H54 A;  5ILD A;  4FJQ A;  1FP3 A;  1N7P A;  1D6U A;  2H6G B;  3QPF A;  2ZZR A;  3KSL B;  2FBA A;  3BGA A;  1LD8 B;  4KTR A;  2WMG A;  2CIS A;  3BVU A;  4J5T A;  3VDA A;  4LNG B;  2F1B A;  3DYO A;  3E7J A;  2FUT A;  3DX1 A;  3BUB A;  3X3Z A;  3SDU A;  2A73 B;  2C11 A;  4GTQ B;  3P2C A;  1W6J A;  1PS3 A;  3M73 A;  4FUS A;  5ILJ A;  1KSD A;  3MUY 1;  2H6I B;  3ALA A;  3HXF B;  3LZ9 A;  1N4Q B;  3DEC A;  1SNZ A;  2WMJ A;  1LVN A;  1W2Z A;  3OXU A;  2D8L A;  2WMK A;  4ONT A;  3EJU A;  2FUQ A;  2H6H B;  3A0O A;  1GXM A;  4JJJ A;  4AQ0 A;  3RRS A;  4FNU A;  5FO7 B;  3BVV A;  2X03 A;  5KBP A;  1IVW A;  3ANJ A;  1HXC A;  2DRO A;  5MEH A;  2F18 A;  2HTB A;  3MWX A;  5E1Q A;  3DDF A;  3D3I A;  4D4B A;  1JYX A;  3M7E A;  3DSW B;  1RWH A;  1KFG A;  1HZF A;  1PX3 A;  3CZJ A;  1KSI A;  1N1Z A;  3SDR A;  3ACS A;  2WVX A;  1DCE B;  1UI8 A;  1S63 B;  2XSG A;  2DRR A;  3T0U A;  2XWB B;  1N7R A;  3IAQ A;  3W7X A;  1DP0 A;  5GZK A;  4D4C A;  1SO0 A;  1HN0 A;  2JKE A;  1F9O A;  1JOV A;  3CU7 A;  2I07 B;  2SQC A;  3SDQ A;  5JPM B;  1CEM A;  1QAL A;  1OJP A;  1RWG A;  1TF4 A;  3VSM A;  2CFD A;  2C10 A;  4K35 A;  5IKH A;  1GAI A;  3T0D A;  4GL3 A;  4GTT B;  3RSY A;  3PZ3 B;  5EAT A;  4LIX A;  4Z4J A;  2ONH A;  1NKG A;  4GTP B;  1V7W A;  2OW6 A;  3LOY A;  1N21 A;  2XN0 A;  3BUD A;  2NOJ A;  1WU6 A;  1NC5 A;  4WVB A;  3SDT A;  2BBC A;  2OKX A;  3PZ4 B;  3IAP A;  3SEP A;  3VDC A;  3M74 A;  1N7N A;  1N9E A;  3C72 B;  2WVZ A;  2KXS A;  1J0M A;  5ILH A;  4OJZ A;  2G02 A;  1N94 B;  4AYO A;  1C3D A;  1NL4 B;  2WOH A;  2V8K A;  4KFD A;  2D73 A;  1IU7 A;  4CJ0 A;  3CV5 A;  3M71 A;  5IKA A;  1N7O A;  4KKI A;  3IMH A;  1A2V A;  3D4Y A;  3Q79 B;  3VW5 A;  1O79 A;  3MI6 A;  3EJQ A;  3OS7 A;  3Q1N A;  2WDA A;  1I8Q A;  1R76 A;  2W0Q A;  1QAK A;  3HII A;  2HTA A;  1TNY B;  1O6H A;  3WUX A;  4MMI A;  2Y74 A;  3E6U A;  4MBG B;  3H2W A;  3UD1 A;  4UFC A;  4BZF A;  1HM2 A;  5A1A A;  3PGB A;  3G4D A;  3DX4 A;  4DOE A;  2NVP A;  2F7R A;  4MMH A;  4BZE A;  1X1J A;  3HXC B;  2BT3 A;  4WVC A;  1NSV A;  1D8E B;  4D6D A;  2CWU A;  2WW1 A;  1TN8 B;  2E2U A;  4BZG A;  1K72 A;  2WY7 A;  2BB5 A;  1TQV A;  1H12 A;  2BB6 A;  3QG0 A;  3CZN A;  3S4D A;  3M75 A;  2OOV C;  3WA2 X;  1JCQ B;  2ZL8 A;  1MMX A;  3EZ8 A;  1D6Y A;  2BRV X;  4V1R A;  1D8D B;  1IVV A;  3D4Z A;  1K1W A;  3QT3 A;  1H35 A;  4F10 A;  1F9D A;  3EU8 A;  5ILZ A;  1SPU A;  1N9A B;  1GXN A;  3GZK A;  3GLY A;  1IA6 A;  1FT1 B;  3H3K A;  1FBW A;  4M76 A;  5DGQ A;  3N0F A;  3SDV A;  2GH4 A;  1AYX A;  4EL8 A;  2R2L B;  2BRP A;  3E37 B;  2XFG A;  1HWW A;  3MV0 1;  4DUV A;  1HXK A;  3M7B A;  3NBB A;  4FNP A;  3WKF A;  1OAC A;  1NS7 A;  5DHK A;  4KFF A;  2YFN A;  2XQW A;  3OBA A;  3EJP A;  3ACT A;  1S64 B;  1CB8 A;  4Q88 A;  1GLM A;  4DI5 A;  4D6H A;  4TXT A;  2IEJ B;  1AVL A;  3KSQ B;  1TQU A;  1WMP A;  3SX1 A;  2CQT A;  2WW3 A;  1PX4 A;  3BS6 A;  3DYM A;  4DOD A;  3A24 A;  1G87 A;  4D4A A;  1HCU A;  1LUR A;  1NSU A;  1H3B A;  3QXQ A;  1N95 B;  2CG0 A;  3I3D A;  5JMF A;  1O1S B;  3CIH A;  2EAE A;  1JZ8 A;  3T2O A;  3TY1 A;  1RWC A;  2V8J A;  1JRQ A;  2F7P A;  1XWQ A;  4D6J A;  1XWT A;  1NSM A;  3E80 A;  1W7C A;  4RNQ A;  3A3V A;  1JYN A;  3PMM A;  5CD2 A;  1MMU A;  4WU0 A;  1YGA A;  3KBT C;  3W7T A;  4Q2B A;  2DRS A;  4D71 A;  1K1Y A;  1O1T B;  3ECQ A;  3K7X A;  1X1H A;  1W5Z A;  1FAE A;  3J7H A;  4FNT A;  3QR8 A;  1UI7 A;  1JYV A;  1X9D A;  3WC3 A;  3PZ2 B;  3QSP A;  1O7D D;  3KII A;  1JZ3 A;  4EV5 A;  2FV1 A;  3EQA A;  2AHF A;  2G0D A;  2OOV A;  2AHG A;  4GTS B;  1F4H A;  3BLC A;  4OZW A;  3W5M A;  5CA3 A;  3M72 A;  5M7I A;  2CWT A;  1RW9 A;  3Q73 B;  2RI9 A;  4WVA A;  2WII B;  3QFZ A;  4L9P B;  5KKB A;  1TNZ B;  3D5R A;  5DGR A;  2WYN A;  5GW7 A;  2WVY A;  3S4A A;  2XHN A;  2EAD A;  1LXK A;  3NFV A;  4OZV A;  5ILI A;  4BTX A;  2E2T A;  2RGK A;  3SQC A;  1UMP A;  2CIQ A;  1G6I A;  1F4A A;  1KZP B;  4C1S A;  1K1X A;  3WKG A;  3BVX A;  1IVX A;  1SII A;  3OED A;  4D72 A; 
#chains in the Genus database with same CATH homology
 1MMY A;  1HM2 A;  5A1A A;  3VD9 A;  1LF9 A;  3T2P A;  4MMH A;  3VD4 A;  4BZE A;  1X1J A;  5JMD A;  3MV1 1;  1OJO A;  1NSV A;  4D6D A;  3NRE A;  2WW1 A;  1N7P A;  2CIR A;  4BZG A;  4D6I A;  1Z45 A;  2WMF A;  3BGA A;  2WMG A;  1NS2 A;  1JZ5 A;  2CIS A;  1C82 A;  3OB8 A;  4J5T A;  1MMX A;  3VDA A;  2BRV X;  1K1W A;  1J0N A;  1NS4 A;  3DYO A;  3E7J A;  2FUT A;  4F10 A;  1NSR A;  1F1S A;  1JZ2 A;  3VSN A;  2WMI B;  4D6F A;  3MUY 1;  2WW2 A;  2WW0 A;  1NS0 A;  1LXM A;  2BRP A;  2WCO A;  3MV0 1;  4DUV A;  4TTG A;  3DEC A;  1NS8 A;  3I3B A;  1NS7 A;  1SNZ A;  3T0A A;  2WMJ A;  1NSX A;  2WMK A;  3OBA A;  2FUQ A;  1OJN A;  3A0O A;  1JZ6 A;  4AQ0 A;  1JZ7 A;  1CB8 A;  2X03 A;  3T0B A;  2JKA A;  4D6H A;  3E1F 1;  2HTB A;  3MWX A;  5E1Q A;  1HMU A;  4D6E A;  1HMW A;  3DYP A;  2BRW A;  3MUZ 1;  1JYX A;  1RWH A;  4D6G A;  3DCD A;  3T09 A;  1PX3 A;  1UG9 A;  3VD5 A;  3CZJ A;  1L7K A;  2WW3 A;  1PX4 A;  1HM3 A;  2WVX A;  3BS6 A;  2XSG A;  3DYM A;  1MMZ A;  3A24 A;  2WMH A;  1JYW A;  1N7R A;  3IAQ A;  1DP0 A;  1LUR A;  3AFL A;  1HN1 A;  1NSU A;  2WZS A;  3WVF A;  1SO0 A;  3K25 A;  3I3D A;  1HN0 A;  5JMF A;  4RNL A;  2JKE A;  1JOV A;  2ZXQ A;  1JZ8 A;  1HV6 A;  3T2O A;  3TY1 A;  1OJP A;  1RWA A;  1RWC A;  1RWG A;  3VSM A;  1NSZ A;  2E24 A;  4D6J A;  1NSM A;  3NNB A;  2E22 A;  3E80 A;  3NJV A;  1JYN A;  3T0D A;  1MMU A;  1YGA A;  1L7J A;  4F13 A;  1TXK A;  4D71 A;  4FNV A;  1K1Y A;  1NKG A;  4DUW A;  3ECQ A;  1X1H A;  4NEI A;  1JZ4 A;  3J7H A;  1F9G A;  1YQ2 A;  1JYV A;  1RWF A;  4OK2 A;  1JZ3 A;  3IAP A;  3SEP A;  3VD3 A;  1LF6 A;  2JKP A;  3VDC A;  1MN0 A;  3T2Q A;  1N7Q A;  1N7N A;  1F4H A;  3BLC A;  4OZW A;  2WVZ A;  1J0M A;  3VD7 A;  1X1I A;  1QAZ A;  4OJZ A;  1RW9 A;  2WMI A;  2D73 A;  1W3Y A;  1ULV A;  3NJX A;  4DUX A;  3T08 A;  1EGU A;  2ZQ0 A;  1N7O A;  2WVX B;  3I3E A;  3IMH A;  1LOH A;  2WVY A;  2XHN A;  3OS7 A;  4BZH A;  3Q1N A;  1NSS A;  3WFA A;  1LXK A;  1I8Q A;  2WDA A;  3NFV A;  2Q1F A;  4OZV A;  3VDB A;  2CIQ A;  1F4A A;  2HTA A;  4E1Y A;  1K1X A;  4MMI A;  4OK4 A;  4D6C A;  1OJM A;  4BZF A;  4D72 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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