2WCOA

Structures of the streptomyces coelicolor a3(2) hyaluronan lyase in complex with oligosaccharide substrates and an inhibitor
Total Genus 263
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
263
sequence length
742
structure length
742
Chain Sequence
b'ADPYDALRRRWLGITLGTGYDPAAEPYASRLAETGERAREHRATMAPTPTSLWPGHPFDPPAGITFAYGRLWTMTEAYVQEGTGATGDPALLADILRGLDHLSATVYHPATTRYGNWWEWQIGSPRLLMDITAALYDHLGADRVAAACAAVDHFVPDAMLGAYTGTSTGANRVDLCRSVALRGVLGRAPAKIALARDALSPVFPYVTKGDGLYADGSFVQHTWVAYSGTYGQVMLDGLGRLFTLLAGSEWEVTDPGRQLVLDSVEHAYAPLIHDGLVMDTVNGRAISRGYLKSDDLHVMRSDHFHGQQLIAAMAVLAGGASNAERERWHARIKGWIERDTVTPVLTAPQFPVADLTRLHAIADAPGEAAPEPVGHHLFAAMDRAVHRRPAFTAGLAMASDRIAHYECGNGENPRGWHTGAGMLTWWANGTRADQYTDWFWPTVDWYRLPGTTVSTKRLADRAGGEWGAPKPDVRWVGGATDGEYAAVGQHLKGLGSTLEARKSWFFLDDAVVCLGAGITCADGVPVETVVDNRNLGEGGTQALVRGRHWAHLEGHGGWIVPGGALRTLREDRTGAWSDINTTSTTERRTRRWQTLWLDHGTDPAGADYVYTVMPGASRAALARRAADRHWLTVLANDDRRQAVSVPSLGLTAANFWQAGTAGPLTTTAGASVLVRRRGRTATLRVSEPPRTGEALEIVWDHPVGAVLRADETVEILATGRRLHLRVTPGVVCTTHECEVTLS'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords PUTATIVE SECRETED LYASE
publication title Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
pubmed doi rcsb
source organism Streptomyces coelicolor a3(2)
molecule tags Lyase
total genus 263
structure length 742
sequence length 742
ec nomenclature
pdb deposition date 2009-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 2wcoA01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 2wcoA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 2wcoA02
4OK4A 3ECQA 2FUQA 3DYMA 1J0MA 1ULVA 3NNBA 3VD9A 1NSSA 4MMIA 1LF6A 1YGAA 2ZQ0A 3NJVA 3NJXA 1J0NA 1JYXA 1JYWA 3CZJA 1DP0A 3T09A 1TXKA 2WCOA 1N7OA 1MMZA 2WMGA 1SNZA 1LXMA 1CB8A 2WW2A 3WFAA 1OJPA 4D6JA 1NS2A 1JZ8A 2Q1FA 5JMFA 3VD5A 1N7RA 3MUZ1 4D6GA 4AQ0A 1OJNA 1NKGA 1HMWA 2E22A 1K1WA 2FUTA 1L7JA 3IAPA 1X1IA 2WMIB 1F9GA 3E7JA 3IAQA 3OB8A 2JKAA 2WDAA 3OBAA 3I3DA 1F4HA 4D6FA 2HTBA 4BZHA 3VSNA 2WVXA 2BRWA 4F10A 2JKPA 1NS0A 3A24A 1MN0A 1NSVA 4NEIA 4DUVA 3T2QA 1N7PA 5JMDA 2BRVX 1NSZA 2JKEA 2WW1A 2WMKA 4OJZA 2XHNA 4D6CA 1NSMA 1RW9A 1EGUA 1SO0A 3NREA 3BGAA 1F1SA 1LXKA 1Z45A 1HMUA 1NSXA 2WVYA 2XSGA 3DYOA 3VDCA 4F13A 1JZ6A 5E1QA 3J7HA 1JYNA 4D6EA 2CIQA 4BZFA 1LURA 3Q1NA 1RWCA 3T0AA 2CIRA 1JZ7A 3E80A 3A0OA 3DECA 4OZWA 1NS8A 1F4AA 1PX4A 4D72A 2WMFA 3VSMA 1MMUA 1N7QA 4D6IA 4D6DA 2D73A 1RWGA 4OK2A 3MUY1 1LOHA 1HM2A 1JZ4A 4DUWA 1L7KA 4MMHA 1HM3A 4D6HA 1JZ3A 1X1HA 1RWFA 3I3EA 2WVXB 4DUXA 2CISA 1NS7A 3T2PA 2BRPA 1W3YA 2WW3A 1LF9A 1MMXA 3OS7A 1NSUA 3T2OA 3VDAA 1OJOA 4FNVA 4TTGA 2ZXQA 4E1YA 3VD3A 4RNLA 3DYPA 1NSRA 2WVZA 1N7NA 3SEPA 1NS4A 3T08A 1RWAA 1K1XA 2WZSA 1X1JA 1OJMA 4D71A 1YQ2A 4BZEA 4OZVA 1PX3A 1MMYA 3IMHA 3AFLA 3MV11 3E1F1 3NFVA 2WW0A 4BZGA 1HV6A 1JZ5A 1C82A 1JOVA 2X03A 1JYVA 3K25A 2WMIA 1HN0A 1UG9A 3I3BA 5A1AA 2E24A 1JZ2A 1QAZA 3VDBA 2HTAA 1HN1A 3VD4A 3DCDA 1RWHA 1K1YA 3MV01 3T0BA 1I8QA 3T0DA 3VD7A 2WMHA 2WMJA 3MWXA
chains in the Genus database with same CATH superfamily
3S4AA 3BVVA 4L6XA 2FUZA 3H2WA 1NC5A 5DGRA 3M7CA 3PQIA 2XN1A 3BVWA 3NJVA 2D1WA 3EZ8A 1J0NA 1H14A 2D8LA 3QXFA 3BUIA 2OW7A 1DP0A 3NJXA 1FPPB 1QAFA 3EU5B 1N7OA 2DRRA 4LNVA 1MMZA 2F7OA 4KFFA 2XWBB 3VXDA 1SA5B 2WW2A 1OJPA 1NS2A 4KKIA 3MPHA 1H35A 1H39A 2H6FB 3CU7A 1DOGA 2WO0A 1OJNA 1LD8B 1KS8A 3RX8A 1IVVA 2FUTA 1O6RA 3SDQA 3N0GA 3PYAA 1GHQA 4DLOA 3I3DA 4FNQA 3CIHA 4BZHA 3S4DA 3SDTA 2HTBA 1GXMA 3DX3A 1UI8A 3WIRA 3W5MA 2JKPA 5ILJA 1G9GA 4FJQA 4NEIA 1OACA 1H12A 3DSSB 2ZBLA 1FBOA 5JMDA 1NSZA 1UI7A 2WMKA 1FAEA 2H6IB 3M78A 4YDEB 3BUDA 2XHNA 4FUSA 3OXUA 1RW9A 5IK0A 2V3PA 3H7LA 4CJ0A 1WMPA 1W6GA 2WVYA 2XSGA 3A3VA 1R34A 3J7HA 4L9PB 4D6EA 4EV2A 2CIQA 3SQCA 4BZFA 1IQXA 1LVNA 1LURA 1K72A 3ACTA 4M76A 4Q2BA 3EJRA 3E80A 1FO3A 3QFYA 1F4AA 1PX4A 2W0QA 1FP3A 3D52A 3EQAA 3NBBA 2V8KA 1N94B 1RWGA 3PZ4B 1D6ZA 1IQYA 3QFZA 5IKAA 3EJSA 3W7SA 3LOYA 2F0YB 1C3DA 1HM2A 4D8OA 3Q73B 2OQEA 3UD1A 1HM3A 3KIIA 3N0FA 2WOFA 2YFOA 1N95B 2CISA 3HIGA 2JJBA 3C72B 2FYVA 1QWUA 2WW3A 1LF9A 3LZ9A 3OS7A 4FXGB 4D4BA 2KXSA 2BBCA 2ZXQA 1R76A 3DDFA 3GT5A 5GW7A 3D50A 1RJOA 3EJUA 1TNZB 1K1XA 1QBQB 1OJMA 5ILYA 3QR8A 4OZVA 1WMOA 3HXCB 2ONHA 1QQFA 2WW0A 3BUPA 1O6QA 1JOVA 2X03A 3RENA 2YIKA 3AMOA 4C1SA 3DX2A 5GZKA 2CG1A 3EUVB 5DHIA 3SDVA 3WIQA 1QWNA 3BVXA 2WY7A 1O6HA 3T0BA 3D3IA 1QALA 2WMJA 5FO9B 1GXNA 3UD2A 2D5JA 1N9AB 1W4NA 5KKBA 1KFGA 3DYMA 4GTRB 1LD7B 1XWTA 3NNBA 3KQ4A 2WIIB 3VD9A 1JCQB 3QXQA 1XWQA 3PZ3B 3S9VA 5AGDA 3T09A 1RKYA 3T33A 2B39A 2EABA 3M72A 2YFNA 2RDYA 1F9DA 3W7WA 2YX9A 3Q75B 2RGKA 3X17A 4D6JA 1O5MB 4GTPB 1D8DB 1HXAA 5ILHA 3U7VA 2WINB 1N7RA 3MUZ1 4AQ0A 3SDRA 2CQTA 4ZG8A 1HMWA 1L7JA 3M76A 2FBAA 1F9GA 4BOKA 2ZIRB 3E7JA 3IAQA 3RJ3A 3OB8A 3W7XA 1TN8B 2JKAA 1W5ZA 3DSXB 3PZ1B 3DPYB 5ILIA 2F7QA 3X3YA 1V5CA 3VSNA 1S64B 2F1BA 3OEDA 3EJPA 1GXOA 3X40A 1IS9A 5ILKA 5GY3A 1FCEA 5CD2A 3VW5A 1HWWA 4DUVA 1N23A 3HXBB 4EV5A 2OQEC 1HZFA 3WIWA 2JKEA 4WVCA 4KFEA 3QG0A 3W7TA 5IL8A 4OJZA 4D6CA 1EGUA 1AYXA 1UT9A 1F1SA 3M75A 4GTMB 3HXFB 4GTVB 1HMUA 2DRQA 5E2JA 3WKHA 1NSXA 3DYOA 3DX0A 3VDCA 5KBPA 1WMNA 3E34B 3QDEA 2JG0A 3BVTA 3T0UA 1RWCA 4TXTA 2WOHA 2CWUA 4FNUA 1JZ7A 4GTTB 1N4SB 3A0OA 3M7BA 2CQSA 4LIXA 4ZRQA 1FO2A 4D72A 4LNGB 3EJTA 1SPUA 4KKJA 1V5DA 1TQWA 4D6DA 4OK2A 1S63B 5EASA 4ZRPA 3KSLB 4XUVA 3DSTB 3SDUA 1TQUA 1KREA 1AVLA 1L7KA 4D6HA 4MU9A 4WU0A 1KKTA 4CJ1A 3E73A 1GSZA 4K35A 4D4AA 1SQCA 2G02A 3T2PA 4AYPA 1MMXA 3CV5A 2AHFA 1NSUA 3QPFA 3T2OA 3VDAA 4TTGA 3ACSA 3Q79B 2Y73A 4DI5A 3BVUA 3VD3A 2C11A 4RNLA 3WVFA 4D4CA 3M00A 4DODA 3WC3A 5IK9A 4D1IA 1NS4A 1H13A 2WZSA 4D71A 1D6UA 1YQ2A 4BZEA 1O79A 2GOXA 3AFLA 3E6UA 3E1F1 1G6IA 2F6DA 3AFJA 5DGQA 3Q7AB 1IVXA 4CE7A 1HV6A 1WU4A 2WYNA 2E2VA 1CLCA 1CEMA 1VD5A 5IKHA 3K25A 4ZH1A 3I3BA 5A1AA 1JZ2A 2DRSA 1QAZA 4TF4A 3M77A 3SFXB 1QX1A 4ONTA 3MV01 3KLSA 3RSYA 4EL8A 4AYRA 3VD7A 4WVBA 3G4FA 1HXGA 1N4RB 4OK4A 4ZH5A 3M7EA 4EHMB 3ECQA 2FUQA 1JRQA 4DOEA 1ULVA 1NSSA 1H54A 4MMIA 1LF6A 1YGAA 2ZQ0A 3MI6A 3NBJA 4YCRA 3CZJA 1JYWA 3M73A 1SA4B 3DSWB 1TXKA 1H36A 1TQSA 2WGQA 3EJQA 1PU4A 1FT1B 5JPNB 2WMGA 5CZLA 1SNZA 4Z4JA 1JCRB 2GZ6A 2E2UA 3ANJA 2Q1FA 1QAKA 2E2TA 5JMFA 4FNRA 4DLQA 4MBGB 4D6GA 2EAEA 2WY8A 1HTYA 1IA7A 2E22A 3WUXA 4D1JA 3IAPA 3EU8A 2ZL8A 2IEJB 2WMIB 1TF4A 2JF4A 5FO8B 2WDAA 4D94A 3KN4A 1UMPA 3WKIA 3S4CA 4D6FA 1F4HA 1AV4A 1TNOB 1SIHA 1NS0A 1KRFA 2KXRA 1W6KA 4RNQA 1FBWA 2BRVX 2WW1A 2R2LB 5ILZA 3BLBA 3PGBA 5FOBB 1TNYB 4FNPA 1SO0A 3HI7A 3WKGA 2FV0A 1LXKA 2A8ZA 1Z45A 4YDOB 4FXKB 2F7RA 4K3AA 1JZ6A 4F13A 5ILDA 5E1QA 1JYNA 2G0DA 1X81B 3Q78B 3BUBA 1KSCA 1DCEB 1FMIA 2QNOA 3Q1NA 1GA2A 3T0AA 1WU6A 5MEHA 3E37B 1NS8A 3DECA 4BTYA 1IA6A 3K7XA 2WYHA 3WA2X 1MMUA 1NI1B 4GAXA 1N22A 1HX9A 1N7QA 1TNUB 2B4FA 4D6IA 2F7PA 1N21A 3MUY1 1LOHA 3PMMA 1JZ4A 2C10A 5M7IA 2EACA 1RQ5A 1JZ3A 1X1HA 1RWFA 3I3EA 1V7VA 3HIIA 2WVXB 3X41A 1MZCB 2NVPA 1NS7A 2CFDA 2BRPA 4GL3A 2RI8A 2PN5A 4FNSA 4FNVA 3DSUB 4E1YA 2ONGA 3DYPA 3H3KA 1NSRA 4L0GA 3Q7FB 1DYUA 5IL3A 3T08A 3BS6A 1X1JA 2DROA 1O1SB 1MMYA 3D51A 5FO7B 2CG0A 1L2AA 3MV11 2A73B 1N20A 3NFVA 1TQVA 4BZGA 1JZ5A 2BEDB 1TN7B 4GTQB 1JYVA 1H37A 3G6JB 1HN0A 1UG9A 2XWJB 3W5NA 2WMIA 3DDGA 2E24A 2HTAA 2J5CA 1HN1A 4BTWA 1XW2A 3X3XA 3DSVB 1K1YA 2FV1A 3PYBA 3T0DA 3AMOB 3QT9A 2CFGA 4LNBB 3P2CA 1IVUA 1H3CA 3M02A 5EAUA 5EATA 1D8EB 1NXCA 1DL2A 1GAIA 1J0MA 3G4DA 3LVTA 2H6HB 4V1RA 3ANIA 3QWTA 1JYXA 3D5RA 2CWTA 2WCOA 1D6YA 1W6CA 3P5RA 1HCUA 1LXMA 2PMVA 3CZNA 1CB8A 3HXEB 1SIIA 3SXXA 1AVKA 3WFAA 2CFLA 1JZ8A 1H3BA 1O7DD 4KFDA 3DX4A 4BTXA 3GZKA 3VD5A 2ZISB 1KZPB 4J5TA 3KBTC 1NKGA 1K1WA 3E30B 1X1IA 1G87A 1US1A 1X9DA 1KSIA 3BLCA 3TY1A 3ANKA 2H6GB 2ZZRA 2BB5A 3M74A 3OBAA 3D5SA 1KSDA 1AGMA 3K5TA 2OOVC 2CWVA 1HXCA 3S4BA 2WVXA 2BRWA 4F10A 4UFCA 2WYIA 2Z07A 2CFWA 1MN0A 3A24A 1TU5A 3E32B 1R33A 3WA3A 1GLMA 1JS4A 1NSVA 3T2QA 1N7PA 1WZZA 1W2ZA 3RX7A 1IVWA 2CFKA 2OKXA 2BB6A 3F59A 1NSMA 3NREA 3D4ZA 2V8IA 1PS3A 3BGAA 1JCSB 4JJJA 4Z4LA 1KZOB 2EADA 3SFYB 2NOJA 1N4QB 3GLYA 1W6JA 3PZ2B 5JPMB 2CIRA 2XFGA 3E33B 3QRYA 4OZWA 3RX5A 4GTOB 3ALAA 2WMFA 2RI9A 2AHGA 5DHKA 4KTPA 3VSMA 5IM1A 1A2VA 4KTRA 2D73A 1O1RB 1N1ZA 2OW6A 1W7CA 3M7LA 3W7UA 4DUWA 1V7WA 1L1YA 5C05A 3KSQB 3BUQA 4MMHA 2XQWA 2I07B 1HXKA 1N4PB 1TQTA 3ON6A 4Q88A 3X42A 1O1TB 1EKMA 2V8JA 1TNBB 1V7XA 4D4DA 4DUXA 3DRAB 1QSJA 1W3YA 1GAHA 1H3AA 3K11A 2F1AA 5M7YA 1OJOA 3N9HA 2P0VA 1TN6B 3WKFA 1N1BA 4GTSB 4AYOA 1WU5A 1N7NA 3RRSA 2WVZA 3SEPA 2PNCA 2V3NA 1FT2B 1KWFA 3M01A 2OOVA 3QSPA 2SQCA 5CA3A 4WVAA 1RWAA 3P5PA 2XN0A 2ALWA 2AFAA 1F9OA 1PX3A 3IMHA 1LTXB 3QT3A 1NL4B 3M71A 1N24A 2GH4A 2VN4A 1IU7A 5IK6A 4V1SA 1C82A 4QT9A 3TF4A 3CZSA 4FNTA 4AYQA 3SX1A 2Y74A 3VDBA 2BT3A 2XN2A 3VD4A 1N9EA 3DCDA 1RWHA 3D4YA 2F18A 3DX1A 1G9JA 3X3ZA 3SAEA 1I8QA 2WMHA 3HXDB 2VN7A 3KBUC 4BOJA 3MWXA
chains in the Genus database with same CATH topology
4OK4A 3ECQA 2FUQA 3DYMA 1J0MA 1ULVA 3NNBA 3VD9A 1NSSA 4MMIA 1LF6A 1YGAA 2ZQ0A 3NJVA 3NJXA 1J0NA 1JYXA 1JYWA 3CZJA 1DP0A 3T09A 1TXKA 2WCOA 1N7OA 1MMZA 2WMGA 1SNZA 1LXMA 1CB8A 2WW2A 3WFAA 1OJPA 4D6JA 1NS2A 1JZ8A 2Q1FA 5JMFA 3VD5A 1N7RA 3MUZ1 4D6GA 4AQ0A 4J5TA 1OJNA 1NKGA 1HMWA 2E22A 1K1WA 2FUTA 1L7JA 3IAPA 1X1IA 2WMIB 1F9GA 3BLCA 3E7JA 3TY1A 3IAQA 3OB8A 2JKAA 2WDAA 3OBAA 3I3DA 1F4HA 4D6FA 2HTBA 4BZHA 3VSNA 2WVXA 2BRWA 4F10A 2JKPA 1NS0A 3A24A 1MN0A 1NSVA 4NEIA 4DUVA 3T2QA 1N7PA 5JMDA 2BRVX 1NSZA 2JKEA 2WW1A 2WMKA 4OJZA 2XHNA 4D6CA 1NSMA 1RW9A 1EGUA 1SO0A 3NREA 3BGAA 1F1SA 1LXKA 1Z45A 1HMUA 1NSXA 2WVYA 2XSGA 3DYOA 3VDCA 4F13A 1JZ6A 5E1QA 3J7HA 1JYNA 4D6EA 2CIQA 4BZFA 1LURA 3Q1NA 1RWCA 3T0AA 2CIRA 1JZ7A 3E80A 3A0OA 3DECA 4OZWA 1NS8A 1F4AA 1PX4A 4D72A 2WMFA 3VSMA 1MMUA 1N7QA 4D6IA 4D6DA 2D73A 1RWGA 4OK2A 3MUY1 1LOHA 1HM2A 1JZ4A 4DUWA 1L7KA 4MMHA 1HM3A 4D6HA 1JZ3A 1X1HA 1RWFA 3I3EA 2WVXB 4DUXA 2CISA 1NS7A 3T2PA 2BRPA 1W3YA 2WW3A 1LF9A 1MMXA 3OS7A 1NSUA 3T2OA 3VDAA 1OJOA 4FNVA 4TTGA 2ZXQA 4E1YA 3VD3A 4RNLA 3WVFA 3DYPA 1NSRA 2WVZA 1N7NA 3SEPA 1NS4A 3T08A 3BS6A 1RWAA 1K1XA 2WZSA 1X1JA 1OJMA 4D71A 1YQ2A 4BZEA 4OZVA 1PX3A 1MMYA 3IMHA 3AFLA 3MV11 3E1F1 3NFVA 2WW0A 4BZGA 1HV6A 1JZ5A 1C82A 1JOVA 2X03A 1JYVA 3K25A 2WMIA 1HN0A 1UG9A 3I3BA 5A1AA 2E24A 1JZ2A 1QAZA 3VDBA 2HTAA 1HN1A 3VD4A 3DCDA 1RWHA 1K1YA 3MV01 3T0BA 1I8QA 3T0DA 3VD7A 2WMHA 2WMJA 3MWXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OK4 A;  3ECQ A;  2FUQ A;  3DYM A;  1J0M A;  1ULV A;  3NNB A;  3VD9 A;  1NSS A;  4MMI A;  1LF6 A;  1YGA A;  2ZQ0 A;  3NJV A;  3NJX A;  1J0N A;  1JYX A;  1JYW A;  3CZJ A;  1DP0 A;  3T09 A;  1TXK A;  2WCO A;  1N7O A;  1MMZ A;  2WMG A;  1SNZ A;  1LXM A;  1CB8 A;  2WW2 A;  3WFA A;  1OJP A;  4D6J A;  1NS2 A;  1JZ8 A;  2Q1F A;  5JMF A;  3VD5 A;  1N7R A;  3MUZ 1;  4D6G A;  4AQ0 A;  1OJN A;  1NKG A;  1HMW A;  2E22 A;  1K1W A;  2FUT A;  1L7J A;  3IAP A;  1X1I A;  2WMI B;  1F9G A;  3E7J A;  3IAQ A;  3OB8 A;  2JKA A;  2WDA A;  3OBA A;  3I3D A;  1F4H A;  4D6F A;  2HTB A;  4BZH A;  3VSN A;  2WVX A;  2BRW A;  4F10 A;  2JKP A;  1NS0 A;  3A24 A;  1MN0 A;  1NSV A;  4NEI A;  4DUV A;  3T2Q A;  1N7P A;  5JMD A;  2BRV X;  1NSZ A;  2JKE A;  2WW1 A;  2WMK A;  4OJZ A;  2XHN A;  4D6C A;  1NSM A;  1RW9 A;  1EGU A;  1SO0 A;  3NRE A;  3BGA A;  1F1S A;  1LXK A;  1Z45 A;  1HMU A;  1NSX A;  2WVY A;  2XSG A;  3DYO A;  3VDC A;  4F13 A;  1JZ6 A;  5E1Q A;  3J7H A;  1JYN A;  4D6E A;  2CIQ A;  4BZF A;  1LUR A;  3Q1N A;  1RWC A;  3T0A A;  2CIR A;  1JZ7 A;  3E80 A;  3A0O A;  3DEC A;  4OZW A;  1NS8 A;  1F4A A;  1PX4 A;  4D72 A;  2WMF A;  3VSM A;  1MMU A;  1N7Q A;  4D6I A;  4D6D A;  2D73 A;  1RWG A;  4OK2 A;  3MUY 1;  1LOH A;  1HM2 A;  1JZ4 A;  4DUW A;  1L7K A;  4MMH A;  1HM3 A;  4D6H A;  1JZ3 A;  1X1H A;  1RWF A;  3I3E A;  2WVX B;  4DUX A;  2CIS A;  1NS7 A;  3T2P A;  2BRP A;  1W3Y A;  2WW3 A;  1LF9 A;  1MMX A;  3OS7 A;  1NSU A;  3T2O A;  3VDA A;  1OJO A;  4FNV A;  4TTG A;  2ZXQ A;  4E1Y A;  3VD3 A;  4RNL A;  3DYP A;  1NSR A;  2WVZ A;  1N7N A;  3SEP A;  1NS4 A;  3T08 A;  1RWA A;  1K1X A;  2WZS A;  1X1J A;  1OJM A;  4D71 A;  1YQ2 A;  4BZE A;  4OZV A;  1PX3 A;  1MMY A;  3IMH A;  3AFL A;  3MV1 1;  3E1F 1;  3NFV A;  2WW0 A;  4BZG A;  1HV6 A;  1JZ5 A;  1C82 A;  1JOV A;  2X03 A;  1JYV A;  3K25 A;  2WMI A;  1HN0 A;  1UG9 A;  3I3B A;  5A1A A;  2E24 A;  1JZ2 A;  1QAZ A;  3VDB A;  2HTA A;  1HN1 A;  3VD4 A;  3DCD A;  1RWH A;  1K1Y A;  3MV0 1;  3T0B A;  1I8Q A;  3T0D A;  3VD7 A;  2WMH A;  2WMJ A;  3MWX A; 
#chains in the Genus database with same CATH topology
 3S4A A;  3BVV A;  4L6X A;  2FUZ A;  3H2W A;  1NC5 A;  5DGR A;  3M7C A;  3PQI A;  2XN1 A;  3BVW A;  3NJV A;  2D1W A;  3EZ8 A;  1J0N A;  1H14 A;  2D8L A;  3QXF A;  3BUI A;  2OW7 A;  1DP0 A;  3NJX A;  1FPP B;  1QAF A;  3EU5 B;  1N7O A;  2DRR A;  4LNV A;  1MMZ A;  2F7O A;  4KFF A;  2XWB B;  3VXD A;  1SA5 B;  2WW2 A;  1OJP A;  1NS2 A;  4KKI A;  3MPH A;  1H35 A;  1H39 A;  2H6F B;  3CU7 A;  1DOG A;  2WO0 A;  1OJN A;  1LD8 B;  1KS8 A;  3RX8 A;  1IVV A;  2FUT A;  1O6R A;  3SDQ A;  3N0G A;  3PYA A;  1GHQ A;  4DLO A;  3I3D A;  4FNQ A;  3CIH A;  4BZH A;  3S4D A;  3SDT A;  2HTB A;  1GXM A;  3DX3 A;  1UI8 A;  3WIR A;  3W5M A;  2JKP A;  5ILJ A;  1G9G A;  4FJQ A;  4NEI A;  1OAC A;  1H12 A;  3DSS B;  2ZBL A;  1FBO A;  5JMD A;  1NSZ A;  1UI7 A;  2WMK A;  1FAE A;  2H6I B;  3M78 A;  4YDE B;  3BUD A;  2XHN A;  4FUS A;  3OXU A;  1RW9 A;  5IK0 A;  2V3P A;  3H7L A;  4CJ0 A;  1WMP A;  1W6G A;  2WVY A;  2XSG A;  3A3V A;  1R34 A;  3J7H A;  4L9P B;  4D6E A;  4EV2 A;  2CIQ A;  3SQC A;  4BZF A;  1IQX A;  1LVN A;  1LUR A;  1K72 A;  3ACT A;  4M76 A;  4Q2B A;  3EJR A;  3E80 A;  1FO3 A;  3QFY A;  1F4A A;  1PX4 A;  2W0Q A;  1FP3 A;  3D52 A;  3EQA A;  3NBB A;  2V8K A;  1N94 B;  1RWG A;  3PZ4 B;  1D6Z A;  1IQY A;  3QFZ A;  5IKA A;  3EJS A;  3W7S A;  3LOY A;  2F0Y B;  1C3D A;  1HM2 A;  4D8O A;  3Q73 B;  2OQE A;  3UD1 A;  1HM3 A;  3KII A;  3N0F A;  2WOF A;  2YFO A;  1N95 B;  2CIS A;  3HIG A;  2JJB A;  3C72 B;  2FYV A;  1QWU A;  2WW3 A;  1LF9 A;  3LZ9 A;  3OS7 A;  4FXG B;  4D4B A;  2KXS A;  2BBC A;  2ZXQ A;  1R76 A;  3DDF A;  3GT5 A;  5GW7 A;  3D50 A;  1RJO A;  3EJU A;  1TNZ B;  1K1X A;  1QBQ B;  1OJM A;  5ILY A;  3QR8 A;  4OZV A;  1WMO A;  3HXC B;  2ONH A;  1QQF A;  2WW0 A;  3BUP A;  1O6Q A;  1JOV A;  2X03 A;  3REN A;  2YIK A;  3AMO A;  4C1S A;  3DX2 A;  5GZK A;  2CG1 A;  3EUV B;  5DHI A;  3SDV A;  3WIQ A;  1QWN A;  3BVX A;  2WY7 A;  1O6H A;  3T0B A;  3D3I A;  1QAL A;  2WMJ A;  5FO9 B;  1GXN A;  3UD2 A;  2D5J A;  1N9A B;  1W4N A;  5KKB A;  1KFG A;  3DYM A;  4GTR B;  1LD7 B;  1XWT A;  3NNB A;  3KQ4 A;  2WII B;  3VD9 A;  1JCQ B;  3QXQ A;  1XWQ A;  3PZ3 B;  3S9V A;  5AGD A;  3T09 A;  1RKY A;  3T33 A;  2B39 A;  2EAB A;  3M72 A;  2YFN A;  2RDY A;  1F9D A;  3W7W A;  2YX9 A;  3Q75 B;  2RGK A;  3X17 A;  4D6J A;  1O5M B;  4GTP B;  1D8D B;  1HXA A;  5ILH A;  3U7V A;  2WIN B;  1N7R A;  3MUZ 1;  4AQ0 A;  3SDR A;  2CQT A;  4ZG8 A;  1HMW A;  1L7J A;  3M76 A;  2FBA A;  1F9G A;  4BOK A;  2ZIR B;  3E7J A;  3IAQ A;  3RJ3 A;  3OB8 A;  3W7X A;  1TN8 B;  2JKA A;  1W5Z A;  3DSX B;  3PZ1 B;  3DPY B;  5ILI A;  2F7Q A;  3X3Y A;  1V5C A;  3VSN A;  1S64 B;  2F1B A;  3OED A;  3EJP A;  1GXO A;  3X40 A;  1IS9 A;  5ILK A;  5GY3 A;  1FCE A;  5CD2 A;  3VW5 A;  1HWW A;  4DUV A;  1N23 A;  3HXB B;  4EV5 A;  2OQE C;  1HZF A;  3WIW A;  2JKE A;  4WVC A;  4KFE A;  3QG0 A;  3W7T A;  5IL8 A;  4OJZ A;  4D6C A;  1EGU A;  1AYX A;  1UT9 A;  1F1S A;  3M75 A;  4GTM B;  3HXF B;  4GTV B;  1HMU A;  2DRQ A;  5E2J A;  3WKH A;  1NSX A;  3DYO A;  3DX0 A;  3VDC A;  5KBP A;  1WMN A;  3E34 B;  3QDE A;  2JG0 A;  3BVT A;  3T0U A;  1RWC A;  4TXT A;  2WOH A;  2CWU A;  4FNU A;  1JZ7 A;  4GTT B;  1N4S B;  3A0O A;  3M7B A;  2CQS A;  4LIX A;  4ZRQ A;  1FO2 A;  4D72 A;  4LNG B;  3EJT A;  1SPU A;  4KKJ A;  1V5D A;  1TQW A;  4D6D A;  4OK2 A;  1S63 B;  5EAS A;  4ZRP A;  3KSL B;  4XUV A;  3DST B;  3SDU A;  1TQU A;  1KRE A;  1AVL A;  1L7K A;  4D6H A;  4MU9 A;  4WU0 A;  1KKT A;  4CJ1 A;  3E73 A;  1GSZ A;  4K35 A;  4D4A A;  1SQC A;  2G02 A;  3T2P A;  4AYP A;  1MMX A;  3CV5 A;  2AHF A;  1NSU A;  3QPF A;  3T2O A;  3VDA A;  4TTG A;  3ACS A;  3Q79 B;  2Y73 A;  4DI5 A;  3BVU A;  3VD3 A;  2C11 A;  4RNL A;  3WVF A;  4D4C A;  3M00 A;  4DOD A;  3WC3 A;  5IK9 A;  4D1I A;  1NS4 A;  1H13 A;  2WZS A;  4D71 A;  1D6U A;  1YQ2 A;  4BZE A;  1O79 A;  2GOX A;  3AFL A;  3E6U A;  3E1F 1;  1G6I A;  2F6D A;  3AFJ A;  5DGQ A;  3Q7A B;  1IVX A;  4CE7 A;  1HV6 A;  1WU4 A;  2WYN A;  2E2V A;  1CLC A;  1CEM A;  1VD5 A;  5IKH A;  3K25 A;  4ZH1 A;  3I3B A;  5A1A A;  1JZ2 A;  2DRS A;  1QAZ A;  4TF4 A;  3M77 A;  3SFX B;  1QX1 A;  4ONT A;  3MV0 1;  3KLS A;  3RSY A;  4EL8 A;  4AYR A;  3VD7 A;  4WVB A;  3G4F A;  1HXG A;  1N4R B;  4OK4 A;  4ZH5 A;  3M7E A;  4EHM B;  3ECQ A;  2FUQ A;  1JRQ A;  4DOE A;  1ULV A;  1NSS A;  1H54 A;  4MMI A;  1LF6 A;  1YGA A;  2ZQ0 A;  3MI6 A;  3NBJ A;  4YCR A;  3CZJ A;  1JYW A;  3M73 A;  1SA4 B;  3DSW B;  1TXK A;  1H36 A;  1TQS A;  2WGQ A;  3EJQ A;  1PU4 A;  1FT1 B;  5JPN B;  2WMG A;  5CZL A;  1SNZ A;  4Z4J A;  1JCR B;  2GZ6 A;  2E2U A;  3ANJ A;  2Q1F A;  1QAK A;  2E2T A;  5JMF A;  4FNR A;  4DLQ A;  4MBG B;  4D6G A;  2EAE A;  2WY8 A;  1HTY A;  1IA7 A;  2E22 A;  3WUX A;  4D1J A;  3IAP A;  3EU8 A;  2ZL8 A;  2IEJ B;  2WMI B;  1TF4 A;  2JF4 A;  5FO8 B;  2WDA A;  4D94 A;  3KN4 A;  1UMP A;  3WKI A;  3S4C A;  4D6F A;  1F4H A;  1AV4 A;  1TNO B;  1SIH A;  1NS0 A;  1KRF A;  2KXR A;  1W6K A;  4RNQ A;  1FBW A;  2BRV X;  2WW1 A;  2R2L B;  5ILZ A;  3BLB A;  3PGB A;  5FOB B;  1TNY B;  4FNP A;  1SO0 A;  3HI7 A;  3WKG A;  2FV0 A;  1LXK A;  2A8Z A;  1Z45 A;  4YDO B;  4FXK B;  2F7R A;  4K3A A;  1JZ6 A;  4F13 A;  5ILD A;  5E1Q A;  1JYN A;  2G0D A;  1X81 B;  3Q78 B;  3BUB A;  1KSC A;  1DCE B;  1FMI A;  2QNO A;  3Q1N A;  1GA2 A;  3T0A A;  1WU6 A;  5MEH A;  3E37 B;  1NS8 A;  3DEC A;  4BTY A;  1IA6 A;  3K7X A;  2WYH A;  3WA2 X;  1MMU A;  1NI1 B;  4GAX A;  1N22 A;  1HX9 A;  1N7Q A;  1TNU B;  2B4F A;  4D6I A;  2F7P A;  1N21 A;  3MUY 1;  1LOH A;  3PMM A;  1JZ4 A;  2C10 A;  5M7I A;  2EAC A;  1RQ5 A;  1JZ3 A;  1X1H A;  1RWF A;  3I3E A;  1V7V A;  3HII A;  2WVX B;  3X41 A;  1MZC B;  2NVP A;  1NS7 A;  2CFD A;  2BRP A;  4GL3 A;  2RI8 A;  2PN5 A;  4FNS A;  4FNV A;  3DSU B;  4E1Y A;  2ONG A;  3DYP A;  3H3K A;  1NSR A;  4L0G A;  3Q7F B;  1DYU A;  5IL3 A;  3T08 A;  3BS6 A;  1X1J A;  2DRO A;  1O1S B;  1MMY A;  3D51 A;  5FO7 B;  2CG0 A;  1L2A A;  3MV1 1;  2A73 B;  1N20 A;  3NFV A;  1TQV A;  4BZG A;  1JZ5 A;  2BED B;  1TN7 B;  4GTQ B;  1JYV A;  1H37 A;  3G6J B;  1HN0 A;  1UG9 A;  2XWJ B;  3W5N A;  2WMI A;  3DDG A;  2E24 A;  2HTA A;  2J5C A;  1HN1 A;  4BTW A;  1XW2 A;  3X3X A;  3DSV B;  1K1Y A;  2FV1 A;  3PYB A;  3T0D A;  3AMO B;  3QT9 A;  2CFG A;  4LNB B;  3P2C A;  1IVU A;  1H3C A;  3M02 A;  5EAU A;  5EAT A;  1D8E B;  1NXC A;  1DL2 A;  1GAI A;  1J0M A;  3G4D A;  3LVT A;  2H6H B;  4V1R A;  3ANI A;  3QWT A;  1JYX A;  3D5R A;  2CWT A;  2WCO A;  1D6Y A;  1W6C A;  3P5R A;  1HCU A;  1LXM A;  2PMV A;  3CZN A;  1CB8 A;  3HXE B;  1SII A;  3SXX A;  1AVK A;  3WFA A;  2CFL A;  1JZ8 A;  1H3B A;  1O7D D;  4KFD A;  3DX4 A;  4BTX A;  3GZK A;  3VD5 A;  2ZIS B;  1KZP B;  4J5T A;  3KBT C;  1NKG A;  1K1W A;  3E30 B;  1X1I A;  1G87 A;  1US1 A;  1X9D A;  1KSI A;  3BLC A;  3TY1 A;  3ANK A;  2H6G B;  2ZZR A;  2BB5 A;  3M74 A;  3OBA A;  3D5S A;  1KSD A;  1AGM A;  3K5T A;  2OOV C;  2CWV A;  1HXC A;  3S4B A;  2WVX A;  2BRW A;  4F10 A;  4UFC A;  2WYI A;  2Z07 A;  2CFW A;  1MN0 A;  3A24 A;  1TU5 A;  3E32 B;  1R33 A;  3WA3 A;  1GLM A;  1JS4 A;  1NSV A;  3T2Q A;  1N7P A;  1WZZ A;  1W2Z A;  3RX7 A;  1IVW A;  2CFK A;  2OKX A;  2BB6 A;  3F59 A;  1NSM A;  3NRE A;  3D4Z A;  2V8I A;  1PS3 A;  3BGA A;  1JCS B;  4JJJ A;  4Z4L A;  1KZO B;  2EAD A;  3SFY B;  2NOJ A;  1N4Q B;  3GLY A;  1W6J A;  3PZ2 B;  5JPM B;  2CIR A;  2XFG A;  3E33 B;  3QRY A;  4OZW A;  3RX5 A;  4GTO B;  3ALA A;  2WMF A;  2RI9 A;  2AHG A;  5DHK A;  4KTP A;  3VSM A;  5IM1 A;  1A2V A;  4KTR A;  2D73 A;  1O1R B;  1N1Z A;  2OW6 A;  1W7C A;  3M7L A;  3W7U A;  4DUW A;  1V7W A;  1L1Y A;  5C05 A;  3KSQ B;  3BUQ A;  4MMH A;  2XQW A;  2I07 B;  1HXK A;  1N4P B;  1TQT A;  3ON6 A;  4Q88 A;  3X42 A;  1O1T B;  1EKM A;  2V8J A;  1TNB B;  1V7X A;  4D4D A;  4DUX A;  3DRA B;  1QSJ A;  1W3Y A;  1GAH A;  1H3A A;  3K11 A;  2F1A A;  5M7Y A;  1OJO A;  3N9H A;  2P0V A;  1TN6 B;  3WKF A;  1N1B A;  4GTS B;  4AYO A;  1WU5 A;  1N7N A;  3RRS A;  2WVZ A;  3SEP A;  2PNC A;  2V3N A;  1FT2 B;  1KWF A;  3M01 A;  2OOV A;  3QSP A;  2SQC A;  5CA3 A;  4WVA A;  1RWA A;  3P5P A;  2XN0 A;  2ALW A;  2AFA A;  1F9O A;  1PX3 A;  3IMH A;  1LTX B;  3QT3 A;  1NL4 B;  3M71 A;  1N24 A;  2GH4 A;  2VN4 A;  1IU7 A;  5IK6 A;  4V1S A;  1C82 A;  4QT9 A;  3TF4 A;  3CZS A;  4FNT A;  4AYQ A;  3SX1 A;  2Y74 A;  3VDB A;  2BT3 A;  2XN2 A;  3VD4 A;  1N9E A;  3DCD A;  1RWH A;  3D4Y A;  2F18 A;  3DX1 A;  1G9J A;  3X3Z A;  3SAE A;  1I8Q A;  2WMH A;  3HXD B;  2VN7 A;  3KBU C;  4BOJ A;  3MWX A; 
#chains in the Genus database with same CATH homology
 4OK4 A;  3ECQ A;  2FUQ A;  3DYM A;  1J0M A;  1ULV A;  3NNB A;  3VD9 A;  1NSS A;  4MMI A;  1LF6 A;  1YGA A;  2ZQ0 A;  3NJV A;  3NJX A;  1J0N A;  1JYX A;  1JYW A;  3CZJ A;  1DP0 A;  3T09 A;  1TXK A;  2WCO A;  1N7O A;  1MMZ A;  2WMG A;  1SNZ A;  1LXM A;  1CB8 A;  2WW2 A;  3WFA A;  1OJP A;  4D6J A;  1NS2 A;  1JZ8 A;  2Q1F A;  5JMF A;  3VD5 A;  1N7R A;  3MUZ 1;  4D6G A;  4AQ0 A;  4J5T A;  1OJN A;  1NKG A;  1HMW A;  2E22 A;  1K1W A;  2FUT A;  1L7J A;  3IAP A;  1X1I A;  2WMI B;  1F9G A;  3BLC A;  3E7J A;  3TY1 A;  3IAQ A;  3OB8 A;  2JKA A;  2WDA A;  3OBA A;  3I3D A;  1F4H A;  4D6F A;  2HTB A;  4BZH A;  3VSN A;  2WVX A;  2BRW A;  4F10 A;  2JKP A;  1NS0 A;  3A24 A;  1MN0 A;  1NSV A;  4NEI A;  4DUV A;  3T2Q A;  1N7P A;  5JMD A;  2BRV X;  1NSZ A;  2JKE A;  2WW1 A;  2WMK A;  4OJZ A;  2XHN A;  4D6C A;  1NSM A;  1RW9 A;  1EGU A;  1SO0 A;  3NRE A;  3BGA A;  1F1S A;  1LXK A;  1Z45 A;  1HMU A;  1NSX A;  2WVY A;  2XSG A;  3DYO A;  3VDC A;  4F13 A;  1JZ6 A;  5E1Q A;  3J7H A;  1JYN A;  4D6E A;  2CIQ A;  4BZF A;  1LUR A;  3Q1N A;  1RWC A;  3T0A A;  2CIR A;  1JZ7 A;  3E80 A;  3A0O A;  3DEC A;  4OZW A;  1NS8 A;  1F4A A;  1PX4 A;  4D72 A;  2WMF A;  3VSM A;  1MMU A;  1N7Q A;  4D6I A;  4D6D A;  2D73 A;  1RWG A;  4OK2 A;  3MUY 1;  1LOH A;  1HM2 A;  1JZ4 A;  4DUW A;  1L7K A;  4MMH A;  1HM3 A;  4D6H A;  1JZ3 A;  1X1H A;  1RWF A;  3I3E A;  2WVX B;  4DUX A;  2CIS A;  1NS7 A;  3T2P A;  2BRP A;  1W3Y A;  2WW3 A;  1LF9 A;  1MMX A;  3OS7 A;  1NSU A;  3T2O A;  3VDA A;  1OJO A;  4FNV A;  4TTG A;  2ZXQ A;  4E1Y A;  3VD3 A;  4RNL A;  3WVF A;  3DYP A;  1NSR A;  2WVZ A;  1N7N A;  3SEP A;  1NS4 A;  3T08 A;  3BS6 A;  1RWA A;  1K1X A;  2WZS A;  1X1J A;  1OJM A;  4D71 A;  1YQ2 A;  4BZE A;  4OZV A;  1PX3 A;  1MMY A;  3IMH A;  3AFL A;  3MV1 1;  3E1F 1;  3NFV A;  2WW0 A;  4BZG A;  1HV6 A;  1JZ5 A;  1C82 A;  1JOV A;  2X03 A;  1JYV A;  3K25 A;  2WMI A;  1HN0 A;  1UG9 A;  3I3B A;  5A1A A;  2E24 A;  1JZ2 A;  1QAZ A;  3VDB A;  2HTA A;  1HN1 A;  3VD4 A;  3DCD A;  1RWH A;  1K1Y A;  3MV0 1;  3T0B A;  1I8Q A;  3T0D A;  3VD7 A;  2WMH A;  2WMJ A;  3MWX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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