1OJNA

Specificity and mechanism of streptococcus pneumoniae hyaluronate lyase: complex of the tyr408phe mutant with 6-sulphated chondroitin disaccharide
Total Genus 258
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
258
sequence length
722
structure length
722
Chain Sequence
VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAFGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structures of Streptococcus Pneumoniae Hyaluronate Lyase in Complex with Chondroitin and Chondroitin Sulfate Disaccharides: Insights Into Specificity and Mechanism of Action
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
molecule keywords HYALURONATE LYASE
total genus 258
structure length 722
sequence length 722
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2003-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1ojnA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1ojnA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1ojnA01
3CZJA 3VD7A 1X1HA 3BGAA 1LF6A 4MMIA 1NSMA 3VDAA 3VD9A 1MMZA 3SEPA 4BZHA 2JKEA 1JZ3A 1JZ6A 1OJOA 3T2QA 1NS2A 3VSNA 3NREA 3J7HA 3NNBA 4BZEA 1I8QA 1N7QA 2HTAA 1RWGA 1HMUA 4TTGA 3VDCA 2E22A 2CISA 4OK2A 4D6FA 1X1JA 1EGUA 1K1XA 4D6EA 1RWAA 3T09A 4FNVA 2XSGA 1HN0A 1LXMA 2BRVX 1Z45A 3MV11 3T0AA 4OZWA 1MMYA 1NS4A 1JZ2A 1HM3A 1UG9A 1NS7A 1DP0A 1JYXA 2WCOA 4NEIA 3MWXA 3MUZ1 1RW9A 1W3YA 1HMWA 2WW2A 1JZ4A 2WMHA 5E1QA 1JYWA 1LURA 3VD4A 2WMKA 2CIQA 3DCDA 1SNZA 2WMFA 2JKPA 3NJXA 3OS7A 2WZSA 4AQ0A 2ZXQA 1F4AA 1LOHA 4MMHA 1NKGA 1PX3A 4DUWA 1F9GA 3E80A 1HN1A 4OJZA 1N7OA 1LF9A 4F13A 2XHNA 3NFVA 2FUQA 5JMDA 3I3EA 3T2PA 3IAQA 2WMJA 2BRWA 3AFLA 2WMIB 3I3BA 1MMUA 4D6GA 1X1IA 3A24A 3I3DA 2ZQ0A 3A0OA 2WVXB 2WW1A 1J0NA 1N7RA 3VSMA 2WW3A 1J0MA 3IAPA 3K25A 1JYVA 1NSZA 1RWFA 3T08A 1JZ5A 1LXKA 1C82A 4D6IA 1TXKA 3DYPA 1JZ8A 2Q1FA 4D71A 3OBAA 2WVXA 3T2OA 1RWCA 1OJPA 1CB8A 1N7NA 1MMXA 2CIRA 3DYOA 1F1SA 4DUVA 1YGAA 1QAZA 2WMGA 4D6HA 2WMIA 4DUXA 1NSSA 2E24A 1ULVA 1N7PA 1L7JA 2JKAA 4F10A 4D6JA 1JZ7A 2WVYA 1F4HA 2D73A 1JOVA 1NSVA 1MN0A 4RNLA 3VD3A 2WW0A 1HV6A 1HM2A 2HTBA 2WDAA 1L7KA 1NS8A 3WFAA 1NSRA 3E1F1 1RWHA 1OJNA 1NSXA 3DECA 3MUY1 3IMHA 3MV01 1PX4A 3T0BA 3VDBA 1K1WA 1YQ2A 3T0DA 3ECQA 1SO0A 1NS0A 3OB8A 2X03A 4OZVA 4D72A 2FUTA 3Q1NA 4D6DA 5JMFA 2WVZA 4D6CA 4BZGA 5A1AA 3E7JA 4E1YA 1OJMA 3VD5A 1NSUA 3NJVA 1K1YA 3DYMA 1JYNA 4OK4A 4BZFA 2BRPA
chains in the Genus database with same CATH superfamily
3VXDA 3WKHA 4MMIA 3T33A 3E33B 2CFWA 1H35A 1MMZA 3SEPA 2WO0A 2XN0A 1D6YA 2ZL8A 3RX7A 5JPNB 3C72B 2CG0A 2G0DA 3HI7A 1WMPA 4FXGB 3PYBA 1O6QA 3M73A 5E2JA 3J7HA 3NNBA 5KBPA 2OQEA 1H36A 1KZOB 1I8QA 3WKGA 1S63B 1HXKA 4Q2BA 3PQIA 3M71A 4OK2A 1G87A 2PMVA 3QR8A 1X1JA 1QWUA 3WKFA 4GTVB 2RI8A 1RWAA 2XSGA 3T0AA 1Z45A 3HIGA 2D5JA 1JZ2A 1UG9A 3E37B 3MWXA 2BBCA 3MUZ1 1QBQB 1W3YA 3E30B 3S4AA 1W6CA 1JZ4A 1JCSB 2ZIRB 2WMKA 1LURA 1N4SB 4WVAA 3DDFA 2JKPA 3NJXA 2WZSA 2ZXQA 2AFAA 3LZ9A 4FNTA 1TNBB 1H3AA 3EJPA 3WA3A 1FO3A 4D4CA 1N7OA 2F7RA 2C10A 5DHIA 3AFLA 3E32B 3I3BA 1H12A 3EJTA 4D6GA 3AFJA 3D5RA 1XWQA 2JG0A 1WU5A 2CFKA 1KWFA 4V1RA 3M74A 1HCUA 4GTMB 1TQVA 2V8JA 1H54A 3G4DA 4LNGB 3WIQA 2CFLA 1HZFA 1N4RB 2IEJB 3EU5B 2FV0A 1NSZA 5GY3A 1IU7A 3N0GA 3KIIA 3T08A 2H6IB 3DPYB 4TXTA 5M7YA 2E2TA 4D71A 4DOEA 2DRRA 1FT1B 4CJ1A 3UD2A 3H3KA 1MMXA 2C11A 3SDRA 2WOFA 1LVNA 3DX1A 1QAZA 2BB6A 4D6HA 2WMIA 2VN4A 1N7PA 1V7XA 3CU7A 1KSCA 4F10A 1GXMA 4D4AA 3WIWA 4BTYA 3N0FA 1JZ7A 2QNOA 2D73A 4KFEA 3CIHA 3M7EA 1NSVA 1US1A 1GSZA 3AMOA 3VD3A 3PZ1B 2GOXA 1DOGA 1O5MB 1L7KA 4K3AA 2H6GB 1TNZB 1RJOA 1WZZA 3QPFA 4RNQA 3D51A 4GAXA 2ZZRA 1QAFA 3SXXA 4AYPA 1D6UA 3CZSA 3M7LA 4GTSB 4ZH1A 2EABA 3QDEA 3VDBA 3VW5A 3ECQA 1SO0A 3EQAA 3M00A 1V5CA 1IVUA 2FUTA 5JMFA 2JJBA 4D6DA 3S9VA 1GXNA 2J5CA 2I07B 2PNCA 3BVXA 1A2VA 1O1SB 2DRQA 1TQWA 3ACSA 3G4FA 3NJVA 3RSYA 3W7XA 2H6HB 1W6KA 3OXUA 3RJ3A 4OK4A 4CJ0A 2BRPA 2FUZA 3TY1A 3SDQA 3ANJA 1NSMA 3VDAA 1H14A 3VD9A 2EACA 3SAEA 4L9PB 4L6XA 2B39A 1G9GA 4ZH5A 3EU8A 1OJOA 2A8ZA 4M76A 1R76A 1RQ5A 1NS2A 3VSNA 4KTRA 3QXFA 2WOHA 3NREA 4FJQA 1N7QA 1HMUA 4TTGA 3W7WA 3LOYA 3PZ3B 2E22A 3QFYA 2XWJB 4D6FA 2E2UA 4LIXA 1EGUA 4D6EA 3BUQA 5ILJA 3SDVA 3T09A 2CWUA 1GLMA 4FNSA 1GA2A 1V7VA 4OZWA 2YIKA 2OOVC 1PU4A 3BVWA 4GTRB 3W7SA 2WW2A 4GL3A 3HIIA 1LD8B 2WMHA 1MZCB 1TU5A 3VD4A 2CIQA 5EATA 1TNUB 1WMNA 4AYRA 1HTYA 4AQ0A 2ALWA 1F4AA 2V3PA 4MMHA 2ONGA 4GTPB 1NKGA 4DUWA 1OACA 4CE7A 1HX9A 1NXCA 4KKIA 4D8OA 1G9JA 3CV5A 2F1BA 1CEMA 3T2PA 2XQWA 3X17A 3U7VA 1AGMA 3M76A 3M01A 5CZLA 1AVLA 1WMOA 1FBOA 2KXSA 5IK0A 3I3DA 4D94A 4V1SA 2WVXB 2EAEA 1J0NA 1N7RA 1UMPA 1QSJA 2F18A 2F7QA 4ZRQA 3RENA 1IQXA 1SQCA 2B4FA 4KTPA 3K25A 3PYAA 3W7TA 4LNBB 3NBJA 5IL3A 2Y73A 3HXBB 2YFOA 1N9AB 2Q1FA 5ILHA 5DGQA 4KFDA 1XWTA 2WVXA 3M7CA 2CFGA 2CIRA 5ILIA 3BLBA 3Q73B 3S4CA 1KSDA 1GHQA 1YGAA 1O1RB 1H13A 3EUVB 3KQ4A 1IA6A 1ULVA 2KXRA 1TQSA 2OW6A 3M75A 2ZBLA 4D6JA 2WVYA 2DROA 3KSQB 3M02A 1QQFA 4GTTB 4K35A 2DRSA 1H39A 3EJRA 1GAIA 2W0QA 3WFAA 4KKJA 1LD7B 4KFFA 1RWHA 3HXFB 3X41A 3QG0A 1O1TB 2V8IA 2NOJA 3HXDB 2F0YB 3T0BA 4DODA 1K1WA 1YQ2A 1VD5A 1K72A 5ILDA 3Q1NA 3M7BA 2YX9A 1SA4B 1N21A 4D6CA 3ANKA 3KSLB 1FBWA 3DSXB 4E1YA 1UI8A 2WYIA 1NSUA 4UFCA 1FCEA 4AYQA 3Q7AB 1N1BA 3PZ4B 4Z4LA 3KBTC 2XFGA 4F13A 4BZFA 3S4BA 1L1YA 3D3IA 1D6ZA 2XN2A 3QSPA 1PS3A 3CZJA 3VD7A 5FOBB 1X1HA 3DSWB 3QT9A 5FO9B 1QX1A 1H3CA 4BZHA 2JKEA 5EAUA 2G02A 1IS9A 4QT9A 3GLYA 3P5RA 4YCRA 3DX2A 1JZ6A 2NVPA 5FO8B 1EKMA 3BUBA 4FNPA 3D52A 4D1IA 5C05A 1N4PB 1W4NA 4BZEA 1XW2A 2HTAA 1RWGA 4J5TA 2AHGA 1N94B 3OEDA 3BVUA 2CG1A 2D1WA 1QALA 2FBAA 1DYUA 1LXMA 2BRVX 3NBBA 3MV11 1N23A 1MMYA 2BT3A 4FNUA 1DP0A 1JYXA 3X3YA 1KRFA 5GW7A 1HMWA 3RX8A 3F59A 5E1QA 1SNZA 3KLSA 2RI9A 3QRYA 1FAEA 2WYNA 3OS7A 4BTWA 1TN6B 3M78A 3DSVB 1JS4A 1C3DA 1JCQB 1SA5B 3E80A 1HXAA 1HN1A 1LF9A 4OJZA 4D4DA 1CLCA 5JMDA 1R34A 3IAQA 5EASA 2BRWA 1V5DA 2XWBB 2WMIB 3W7UA 1MMUA 4MU9A 1WU6A 3X42A 2XN1A 2E2VA 3A24A 4TF4A 2WW1A 1TNYB 4EV5A 2H6FB 1N20A 3VSMA 3ACTA 4WU0A 5CA3A 3MPHA 2WW3A 3DX0A 1NL4B 1J0MA 1IVWA 1KSIA 3SQCA 3BUDA 3X3XA 1IQYA 1W7CA 1TNOB 3DRAB 5IKAA 4ZRPA 4GTQB 1JZ5A 1C82A 4ZG8A 5MEHA 1JZ8A 2CQSA 1KFGA 1RKYA 1HWWA 4FNQA 3T2OA 1AYXA 1TN8B 2Z07A 1HXCA 3SFYB 1CB8A 1W2ZA 5M7IA 3D4YA 3DDGA 4FNRA 5JPMB 3Q7FB 2WMGA 4DUXA 4EL8A 1L2AA 1L7JA 2AHFA 1UI7A 1O79A 1X9DA 3D5SA 2GZ6A 1F4HA 2GH4A 1N95B 1JOVA 4EV2A 1G6IA 2ONHA 3BVTA 1MN0A 2BEDB 4DI5A 1TQUA 4RNLA 1NI1B 1O6RA 5IM1A 3EJQA 2HTBA 2SQCA 3HXEB 1SPUA 1OJNA 1NSXA 3MUY1 1UT9A 1FT2B 3PMMA 4GTOB 3SDTA 3T0DA 4Q88A 3WVFA 3Q79B 1TQTA 2OW7A 3SFXB 1V7WA 2X03A 4OZVA 1NS0A 4YDOB 3OB8A 5GZKA 2WVZA 5IK6A 3E7JA 1H3BA 3N9HA 4DLOA 1GAHA 4FUSA 1LTXB 3QFZA 1K1YA 5ILKA 3KN4A 4ONTA 1JYNA 1JCRB 3WKIA 1IVVA 4C1SA 4BOJA 2ZISB 1LF6A 3BGAA 3WIRA 1GXOA 3QT3A 3A3VA 1N9EA 1JZ3A 3SDUA 3P2CA 4D1JA 2F7PA 3PGBA 4WVCA 5KKBA 3T2QA 1FO2A 5ILZA 1IVXA 3VDCA 1N1ZA 2CISA 3WA2X 3DX4A 3QWTA 1SIIA 1K1XA 4BTXA 3Q75B 2F7OA 4LNVA 2P0VA 2WYHA 4FNVA 1JRQA 2FYVA 1HN0A 3M72A 1AV4A 2CWTA 2D8LA 3ALAA 3CZNA 1NS4A 1HM3A 1AVKA 1NS7A 2WCOA 4NEIA 2OKXA 3UD1A 5DHKA 1RW9A 4JJJA 1JYWA 2VN7A 1WU4A 3DCDA 2WMFA 4D4BA 2FV1A 3W5NA 1DCEB 1SIHA 3K7XA 4WVBA 3D50A 3EZ8A 2WY7A 1LOHA 3P5PA 1PX3A 3HXCB 3WC3A 1F9GA 3T0UA 3E73A 1F9DA 2EADA 2V8KA 1FMIA 5DGRA 1TN7B 3Q78B 3SX1A 2XHNA 3BUIA 1FP3A 4DLQA 3NFVA 2FUQA 2R2LB 3EJSA 3I3EA 2WMJA 5CD2A 3E6UA 2OQEC 4AYOA 2CWVA 2WY8A 1X1IA 3DSUB 1W5ZA 2ZQ0A 3A0OA 2WINB 2F1AA 5IK9A 3X3ZA 3K11A 5ILYA 3PZ2B 2YFNA 4L0GA 4FXKB 1O6HA 1S64B 1QWNA 3DSSB 3IAPA 1N24A 1JYVA 3X40A 4YDEB 2RDYA 3DX3A 5IKHA 2JF4A 1RWFA 3K5TA 3AMOB 1KS8A 1LXKA 4Z4JA 4D6IA 1TXKA 2WGQA 3DYPA 3OBAA 1W6JA 1RWCA 1OJPA 3WUXA 1N7NA 3E34B 3BLCA 3DYOA 1F1SA 4DUVA 3EJUA 2CQTA 1KREA 1NSSA 2E24A 3GT5A 2Y74A 1R33A 1O7DD 2JKAA 5AGDA 1IA7A 2BB5A 2CFDA 1W6GA 3W5MA 2RGKA 4MBGB 4XUVA 4EHMB 1HXGA 2WW0A 1HV6A 3KBUC 3DSTB 4BOKA 2PN5A 3LVTA 1HM2A 2F6DA 3H2WA 2WDAA 5IL8A 1NS8A 1DL2A 3H7LA 1NSRA 3E1F1 1D8EB 3BVVA 3RRSA 3ON6A 1FPPB 3DECA 5FO7B 3TF4A 3RX5A 3IMHA 3MV01 2A73B 1PX4A 3S4DA 1X81B 3BUPA 3M77A 3MI6A 3QXQA 4D72A 5A1AA 1D8DB 3ANIA 4BZGA 3G6JB 2OOVA 2WIIB 3D4ZA 3BS6A 1TF4A 1OJMA 1H37A 3GZKA 1F9OA 1KKTA 1N22A 3VD5A 1NC5A 2V3NA 3DYMA 1N4QB 1QAKA 1KZPB
chains in the Genus database with same CATH topology
3TY1A 3CZJA 3VD7A 1X1HA 3BGAA 1LF6A 4MMIA 1NSMA 3VDAA 3VD9A 1MMZA 3SEPA 4BZHA 2JKEA 1JZ3A 1JZ6A 1OJOA 3T2QA 1NS2A 3VSNA 3NREA 3J7HA 3NNBA 4BZEA 1I8QA 1N7QA 2HTAA 1RWGA 1HMUA 4J5TA 4TTGA 3VDCA 2E22A 2CISA 4OK2A 4D6FA 1X1JA 1EGUA 1K1XA 4D6EA 1RWAA 3T09A 4FNVA 2XSGA 1HN0A 1LXMA 2BRVX 1Z45A 3MV11 3T0AA 4OZWA 1MMYA 1NS4A 1JZ2A 1HM3A 1UG9A 1NS7A 1DP0A 1JYXA 2WCOA 4NEIA 3MWXA 3MUZ1 1RW9A 1W3YA 1HMWA 2WW2A 1JZ4A 2WMHA 5E1QA 1JYWA 1LURA 3VD4A 2WMKA 2CIQA 3DCDA 1SNZA 2WMFA 2JKPA 3NJXA 3OS7A 2WZSA 4AQ0A 2ZXQA 1F4AA 1LOHA 4MMHA 1NKGA 1PX3A 4DUWA 1F9GA 3E80A 1HN1A 4OJZA 1N7OA 1LF9A 4F13A 2XHNA 3NFVA 2FUQA 5JMDA 3I3EA 3T2PA 3IAQA 2WMJA 2BRWA 3AFLA 2WMIB 3I3BA 1MMUA 4D6GA 1X1IA 3A24A 3I3DA 2ZQ0A 3A0OA 2WVXB 2WW1A 1J0NA 1N7RA 3VSMA 2WW3A 1J0MA 3IAPA 3K25A 1JYVA 1NSZA 1RWFA 3T08A 1JZ5A 1LXKA 1C82A 4D6IA 1TXKA 3DYPA 1JZ8A 2Q1FA 4D71A 3OBAA 2WVXA 3T2OA 1RWCA 1OJPA 1CB8A 1N7NA 1MMXA 2CIRA 3BLCA 3DYOA 1F1SA 4DUVA 1YGAA 1QAZA 2WMGA 4D6HA 2WMIA 4DUXA 1NSSA 2E24A 1ULVA 1N7PA 1L7JA 2JKAA 4F10A 4D6JA 1JZ7A 2WVYA 1F4HA 2D73A 1JOVA 1NSVA 1MN0A 4RNLA 3VD3A 2WW0A 1HV6A 1HM2A 2HTBA 2WDAA 1L7KA 1NS8A 3WFAA 1NSRA 3E1F1 1RWHA 1OJNA 1NSXA 3DECA 3MUY1 3IMHA 3MV01 1PX4A 3T0BA 3VDBA 1K1WA 1YQ2A 3T0DA 3WVFA 3ECQA 1SO0A 1NS0A 3OB8A 2X03A 4OZVA 4D72A 2FUTA 3Q1NA 4D6DA 5JMFA 2WVZA 4D6CA 4BZGA 5A1AA 3E7JA 3BS6A 4E1YA 1OJMA 3VD5A 1NSUA 3NJVA 1K1YA 3DYMA 1JYNA 4OK4A 4BZFA 2BRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CZJ A;  3VD7 A;  1X1H A;  3BGA A;  1LF6 A;  4MMI A;  1NSM A;  3VDA A;  3VD9 A;  1MMZ A;  3SEP A;  4BZH A;  2JKE A;  1JZ3 A;  1JZ6 A;  1OJO A;  3T2Q A;  1NS2 A;  3VSN A;  3NRE A;  3J7H A;  3NNB A;  4BZE A;  1I8Q A;  1N7Q A;  2HTA A;  1RWG A;  1HMU A;  4TTG A;  3VDC A;  2E22 A;  2CIS A;  4OK2 A;  4D6F A;  1X1J A;  1EGU A;  1K1X A;  4D6E A;  1RWA A;  3T09 A;  4FNV A;  2XSG A;  1HN0 A;  1LXM A;  2BRV X;  1Z45 A;  3MV1 1;  3T0A A;  4OZW A;  1MMY A;  1NS4 A;  1JZ2 A;  1HM3 A;  1UG9 A;  1NS7 A;  1DP0 A;  1JYX A;  2WCO A;  4NEI A;  3MWX A;  3MUZ 1;  1RW9 A;  1W3Y A;  1HMW A;  2WW2 A;  1JZ4 A;  2WMH A;  5E1Q A;  1JYW A;  1LUR A;  3VD4 A;  2WMK A;  2CIQ A;  3DCD A;  1SNZ A;  2WMF A;  2JKP A;  3NJX A;  3OS7 A;  2WZS A;  4AQ0 A;  2ZXQ A;  1F4A A;  1LOH A;  4MMH A;  1NKG A;  1PX3 A;  4DUW A;  1F9G A;  3E80 A;  1HN1 A;  4OJZ A;  1N7O A;  1LF9 A;  4F13 A;  2XHN A;  3NFV A;  2FUQ A;  5JMD A;  3I3E A;  3T2P A;  3IAQ A;  2WMJ A;  2BRW A;  3AFL A;  2WMI B;  3I3B A;  1MMU A;  4D6G A;  1X1I A;  3A24 A;  3I3D A;  2ZQ0 A;  3A0O A;  2WVX B;  2WW1 A;  1J0N A;  1N7R A;  3VSM A;  2WW3 A;  1J0M A;  3IAP A;  3K25 A;  1JYV A;  1NSZ A;  1RWF A;  3T08 A;  1JZ5 A;  1LXK A;  1C82 A;  4D6I A;  1TXK A;  3DYP A;  1JZ8 A;  2Q1F A;  4D71 A;  3OBA A;  2WVX A;  3T2O A;  1RWC A;  1OJP A;  1CB8 A;  1N7N A;  1MMX A;  2CIR A;  3DYO A;  1F1S A;  4DUV A;  1YGA A;  1QAZ A;  2WMG A;  4D6H A;  2WMI A;  4DUX A;  1NSS A;  2E24 A;  1ULV A;  1N7P A;  1L7J A;  2JKA A;  4F10 A;  4D6J A;  1JZ7 A;  2WVY A;  1F4H A;  2D73 A;  1JOV A;  1NSV A;  1MN0 A;  4RNL A;  3VD3 A;  2WW0 A;  1HV6 A;  1HM2 A;  2HTB A;  2WDA A;  1L7K A;  1NS8 A;  3WFA A;  1NSR A;  3E1F 1;  1RWH A;  1OJN A;  1NSX A;  3DEC A;  3MUY 1;  3IMH A;  3MV0 1;  1PX4 A;  3T0B A;  3VDB A;  1K1W A;  1YQ2 A;  3T0D A;  3ECQ A;  1SO0 A;  1NS0 A;  3OB8 A;  2X03 A;  4OZV A;  4D72 A;  2FUT A;  3Q1N A;  4D6D A;  5JMF A;  2WVZ A;  4D6C A;  4BZG A;  5A1A A;  3E7J A;  4E1Y A;  1OJM A;  3VD5 A;  1NSU A;  3NJV A;  1K1Y A;  3DYM A;  1JYN A;  4OK4 A;  4BZF A;  2BRP A; 
#chains in the Genus database with same CATH topology
 3VXD A;  3WKH A;  4MMI A;  3T33 A;  3E33 B;  2CFW A;  1H35 A;  1MMZ A;  3SEP A;  2WO0 A;  2XN0 A;  1D6Y A;  2ZL8 A;  3RX7 A;  5JPN B;  3C72 B;  2CG0 A;  2G0D A;  3HI7 A;  1WMP A;  4FXG B;  3PYB A;  1O6Q A;  3M73 A;  5E2J A;  3J7H A;  3NNB A;  5KBP A;  2OQE A;  1H36 A;  1KZO B;  1I8Q A;  3WKG A;  1S63 B;  1HXK A;  4Q2B A;  3PQI A;  3M71 A;  4OK2 A;  1G87 A;  2PMV A;  3QR8 A;  1X1J A;  1QWU A;  3WKF A;  4GTV B;  2RI8 A;  1RWA A;  2XSG A;  3T0A A;  1Z45 A;  3HIG A;  2D5J A;  1JZ2 A;  1UG9 A;  3E37 B;  3MWX A;  2BBC A;  3MUZ 1;  1QBQ B;  1W3Y A;  3E30 B;  3S4A A;  1W6C A;  1JZ4 A;  1JCS B;  2ZIR B;  2WMK A;  1LUR A;  1N4S B;  4WVA A;  3DDF A;  2JKP A;  3NJX A;  2WZS A;  2ZXQ A;  2AFA A;  3LZ9 A;  4FNT A;  1TNB B;  1H3A A;  3EJP A;  3WA3 A;  1FO3 A;  4D4C A;  1N7O A;  2F7R A;  2C10 A;  5DHI A;  3AFL A;  3E32 B;  3I3B A;  1H12 A;  3EJT A;  4D6G A;  3AFJ A;  3D5R A;  1XWQ A;  2JG0 A;  1WU5 A;  2CFK A;  1KWF A;  4V1R A;  3M74 A;  1HCU A;  4GTM B;  1TQV A;  2V8J A;  1H54 A;  3G4D A;  4LNG B;  3WIQ A;  2CFL A;  1HZF A;  1N4R B;  2IEJ B;  3EU5 B;  2FV0 A;  1NSZ A;  5GY3 A;  1IU7 A;  3N0G A;  3KII A;  3T08 A;  2H6I B;  3DPY B;  4TXT A;  5M7Y A;  2E2T A;  4D71 A;  4DOE A;  2DRR A;  1FT1 B;  4CJ1 A;  3UD2 A;  3H3K A;  1MMX A;  2C11 A;  3SDR A;  2WOF A;  1LVN A;  3DX1 A;  1QAZ A;  2BB6 A;  4D6H A;  2WMI A;  2VN4 A;  1N7P A;  1V7X A;  3CU7 A;  1KSC A;  4F10 A;  1GXM A;  4D4A A;  3WIW A;  4BTY A;  3N0F A;  1JZ7 A;  2QNO A;  2D73 A;  4KFE A;  3CIH A;  3M7E A;  1NSV A;  1US1 A;  1GSZ A;  3AMO A;  3VD3 A;  3PZ1 B;  2GOX A;  1DOG A;  1O5M B;  1L7K A;  4K3A A;  2H6G B;  1TNZ B;  1RJO A;  1WZZ A;  3QPF A;  4RNQ A;  3D51 A;  4GAX A;  2ZZR A;  1QAF A;  3SXX A;  4AYP A;  1D6U A;  3CZS A;  3M7L A;  4GTS B;  4ZH1 A;  2EAB A;  3QDE A;  3VDB A;  3VW5 A;  3ECQ A;  1SO0 A;  3EQA A;  3M00 A;  1V5C A;  1IVU A;  2FUT A;  5JMF A;  2JJB A;  4D6D A;  3S9V A;  1GXN A;  2J5C A;  2I07 B;  2PNC A;  3BVX A;  1A2V A;  1O1S B;  2DRQ A;  1TQW A;  3ACS A;  3G4F A;  3NJV A;  3RSY A;  3W7X A;  2H6H B;  1W6K A;  3OXU A;  3RJ3 A;  4OK4 A;  4CJ0 A;  2BRP A;  2FUZ A;  3TY1 A;  3SDQ A;  3ANJ A;  1NSM A;  3VDA A;  1H14 A;  3VD9 A;  2EAC A;  3SAE A;  4L9P B;  4L6X A;  2B39 A;  1G9G A;  4ZH5 A;  3EU8 A;  1OJO A;  2A8Z A;  4M76 A;  1R76 A;  1RQ5 A;  1NS2 A;  3VSN A;  4KTR A;  3QXF A;  2WOH A;  3NRE A;  4FJQ A;  1N7Q A;  1HMU A;  4TTG A;  3W7W A;  3LOY A;  3PZ3 B;  2E22 A;  3QFY A;  2XWJ B;  4D6F A;  2E2U A;  4LIX A;  1EGU A;  4D6E A;  3BUQ A;  5ILJ A;  3SDV A;  3T09 A;  2CWU A;  1GLM A;  4FNS A;  1GA2 A;  1V7V A;  4OZW A;  2YIK A;  2OOV C;  1PU4 A;  3BVW A;  4GTR B;  3W7S A;  2WW2 A;  4GL3 A;  3HII A;  1LD8 B;  2WMH A;  1MZC B;  1TU5 A;  3VD4 A;  2CIQ A;  5EAT A;  1TNU B;  1WMN A;  4AYR A;  1HTY A;  4AQ0 A;  2ALW A;  1F4A A;  2V3P A;  4MMH A;  2ONG A;  4GTP B;  1NKG A;  4DUW A;  1OAC A;  4CE7 A;  1HX9 A;  1NXC A;  4KKI A;  4D8O A;  1G9J A;  3CV5 A;  2F1B A;  1CEM A;  3T2P A;  2XQW A;  3X17 A;  3U7V A;  1AGM A;  3M76 A;  3M01 A;  5CZL A;  1AVL A;  1WMO A;  1FBO A;  2KXS A;  5IK0 A;  3I3D A;  4D94 A;  4V1S A;  2WVX B;  2EAE A;  1J0N A;  1N7R A;  1UMP A;  1QSJ A;  2F18 A;  2F7Q A;  4ZRQ A;  3REN A;  1IQX A;  1SQC A;  2B4F A;  4KTP A;  3K25 A;  3PYA A;  3W7T A;  4LNB B;  3NBJ A;  5IL3 A;  2Y73 A;  3HXB B;  2YFO A;  1N9A B;  2Q1F A;  5ILH A;  5DGQ A;  4KFD A;  1XWT A;  2WVX A;  3M7C A;  2CFG A;  2CIR A;  5ILI A;  3BLB A;  3Q73 B;  3S4C A;  1KSD A;  1GHQ A;  1YGA A;  1O1R B;  1H13 A;  3EUV B;  3KQ4 A;  1IA6 A;  1ULV A;  2KXR A;  1TQS A;  2OW6 A;  3M75 A;  2ZBL A;  4D6J A;  2WVY A;  2DRO A;  3KSQ B;  3M02 A;  1QQF A;  4GTT B;  4K35 A;  2DRS A;  1H39 A;  3EJR A;  1GAI A;  2W0Q A;  3WFA A;  4KKJ A;  1LD7 B;  4KFF A;  1RWH A;  3HXF B;  3X41 A;  3QG0 A;  1O1T B;  2V8I A;  2NOJ A;  3HXD B;  2F0Y B;  3T0B A;  4DOD A;  1K1W A;  1YQ2 A;  1VD5 A;  1K72 A;  5ILD A;  3Q1N A;  3M7B A;  2YX9 A;  1SA4 B;  1N21 A;  4D6C A;  3ANK A;  3KSL B;  1FBW A;  3DSX B;  4E1Y A;  1UI8 A;  2WYI A;  1NSU A;  4UFC A;  1FCE A;  4AYQ A;  3Q7A B;  1N1B A;  3PZ4 B;  4Z4L A;  3KBT C;  2XFG A;  4F13 A;  4BZF A;  3S4B A;  1L1Y A;  3D3I A;  1D6Z A;  2XN2 A;  3QSP A;  1PS3 A;  3CZJ A;  3VD7 A;  5FOB B;  1X1H A;  3DSW B;  3QT9 A;  5FO9 B;  1QX1 A;  1H3C A;  4BZH A;  2JKE A;  5EAU A;  2G02 A;  1IS9 A;  4QT9 A;  3GLY A;  3P5R A;  4YCR A;  3DX2 A;  1JZ6 A;  2NVP A;  5FO8 B;  1EKM A;  3BUB A;  4FNP A;  3D52 A;  4D1I A;  5C05 A;  1N4P B;  1W4N A;  4BZE A;  1XW2 A;  2HTA A;  1RWG A;  4J5T A;  2AHG A;  1N94 B;  3OED A;  3BVU A;  2CG1 A;  2D1W A;  1QAL A;  2FBA A;  1DYU A;  1LXM A;  2BRV X;  3NBB A;  3MV1 1;  1N23 A;  1MMY A;  2BT3 A;  4FNU A;  1DP0 A;  1JYX A;  3X3Y A;  1KRF A;  5GW7 A;  1HMW A;  3RX8 A;  3F59 A;  5E1Q A;  1SNZ A;  3KLS A;  2RI9 A;  3QRY A;  1FAE A;  2WYN A;  3OS7 A;  4BTW A;  1TN6 B;  3M78 A;  3DSV B;  1JS4 A;  1C3D A;  1JCQ B;  1SA5 B;  3E80 A;  1HXA A;  1HN1 A;  1LF9 A;  4OJZ A;  4D4D A;  1CLC A;  5JMD A;  1R34 A;  3IAQ A;  5EAS A;  2BRW A;  1V5D A;  2XWB B;  2WMI B;  3W7U A;  1MMU A;  4MU9 A;  1WU6 A;  3X42 A;  2XN1 A;  2E2V A;  3A24 A;  4TF4 A;  2WW1 A;  1TNY B;  4EV5 A;  2H6F B;  1N20 A;  3VSM A;  3ACT A;  4WU0 A;  5CA3 A;  3MPH A;  2WW3 A;  3DX0 A;  1NL4 B;  1J0M A;  1IVW A;  1KSI A;  3SQC A;  3BUD A;  3X3X A;  1IQY A;  1W7C A;  1TNO B;  3DRA B;  5IKA A;  4ZRP A;  4GTQ B;  1JZ5 A;  1C82 A;  4ZG8 A;  5MEH A;  1JZ8 A;  2CQS A;  1KFG A;  1RKY A;  1HWW A;  4FNQ A;  3T2O A;  1AYX A;  1TN8 B;  2Z07 A;  1HXC A;  3SFY B;  1CB8 A;  1W2Z A;  5M7I A;  3D4Y A;  3DDG A;  4FNR A;  5JPM B;  3Q7F B;  2WMG A;  4DUX A;  4EL8 A;  1L2A A;  1L7J A;  2AHF A;  1UI7 A;  1O79 A;  1X9D A;  3D5S A;  2GZ6 A;  1F4H A;  2GH4 A;  1N95 B;  1JOV A;  4EV2 A;  1G6I A;  2ONH A;  3BVT A;  1MN0 A;  2BED B;  4DI5 A;  1TQU A;  4RNL A;  1NI1 B;  1O6R A;  5IM1 A;  3EJQ A;  2HTB A;  2SQC A;  3HXE B;  1SPU A;  1OJN A;  1NSX A;  3MUY 1;  1UT9 A;  1FT2 B;  3PMM A;  4GTO B;  3SDT A;  3T0D A;  4Q88 A;  3WVF A;  3Q79 B;  1TQT A;  2OW7 A;  3SFX B;  1V7W A;  2X03 A;  4OZV A;  1NS0 A;  4YDO B;  3OB8 A;  5GZK A;  2WVZ A;  5IK6 A;  3E7J A;  1H3B A;  3N9H A;  4DLO A;  1GAH A;  4FUS A;  1LTX B;  3QFZ A;  1K1Y A;  5ILK A;  3KN4 A;  4ONT A;  1JYN A;  1JCR B;  3WKI A;  1IVV A;  4C1S A;  4BOJ A;  2ZIS B;  1LF6 A;  3BGA A;  3WIR A;  1GXO A;  3QT3 A;  3A3V A;  1N9E A;  1JZ3 A;  3SDU A;  3P2C A;  4D1J A;  2F7P A;  3PGB A;  4WVC A;  5KKB A;  3T2Q A;  1FO2 A;  5ILZ A;  1IVX A;  3VDC A;  1N1Z A;  2CIS A;  3WA2 X;  3DX4 A;  3QWT A;  1SII A;  1K1X A;  4BTX A;  3Q75 B;  2F7O A;  4LNV A;  2P0V A;  2WYH A;  4FNV A;  1JRQ A;  2FYV A;  1HN0 A;  3M72 A;  1AV4 A;  2CWT A;  2D8L A;  3ALA A;  3CZN A;  1NS4 A;  1HM3 A;  1AVK A;  1NS7 A;  2WCO A;  4NEI A;  2OKX A;  3UD1 A;  5DHK A;  1RW9 A;  4JJJ A;  1JYW A;  2VN7 A;  1WU4 A;  3DCD A;  2WMF A;  4D4B A;  2FV1 A;  3W5N A;  1DCE B;  1SIH A;  3K7X A;  4WVB A;  3D50 A;  3EZ8 A;  2WY7 A;  1LOH A;  3P5P A;  1PX3 A;  3HXC B;  3WC3 A;  1F9G A;  3T0U A;  3E73 A;  1F9D A;  2EAD A;  2V8K A;  1FMI A;  5DGR A;  1TN7 B;  3Q78 B;  3SX1 A;  2XHN A;  3BUI A;  1FP3 A;  4DLQ A;  3NFV A;  2FUQ A;  2R2L B;  3EJS A;  3I3E A;  2WMJ A;  5CD2 A;  3E6U A;  2OQE C;  4AYO A;  2CWV A;  2WY8 A;  1X1I A;  3DSU B;  1W5Z A;  2ZQ0 A;  3A0O A;  2WIN B;  2F1A A;  5IK9 A;  3X3Z A;  3K11 A;  5ILY A;  3PZ2 B;  2YFN A;  4L0G A;  4FXK B;  1O6H A;  1S64 B;  1QWN A;  3DSS B;  3IAP A;  1N24 A;  1JYV A;  3X40 A;  4YDE B;  2RDY A;  3DX3 A;  5IKH A;  2JF4 A;  1RWF A;  3K5T A;  3AMO B;  1KS8 A;  1LXK A;  4Z4J A;  4D6I A;  1TXK A;  2WGQ A;  3DYP A;  3OBA A;  1W6J A;  1RWC A;  1OJP A;  3WUX A;  1N7N A;  3E34 B;  3BLC A;  3DYO A;  1F1S A;  4DUV A;  3EJU A;  2CQT A;  1KRE A;  1NSS A;  2E24 A;  3GT5 A;  2Y74 A;  1R33 A;  1O7D D;  2JKA A;  5AGD A;  1IA7 A;  2BB5 A;  2CFD A;  1W6G A;  3W5M A;  2RGK A;  4MBG B;  4XUV A;  4EHM B;  1HXG A;  2WW0 A;  1HV6 A;  3KBU C;  3DST B;  4BOK A;  2PN5 A;  3LVT A;  1HM2 A;  2F6D A;  3H2W A;  2WDA A;  5IL8 A;  1NS8 A;  1DL2 A;  3H7L A;  1NSR A;  3E1F 1;  1D8E B;  3BVV A;  3RRS A;  3ON6 A;  1FPP B;  3DEC A;  5FO7 B;  3TF4 A;  3RX5 A;  3IMH A;  3MV0 1;  2A73 B;  1PX4 A;  3S4D A;  1X81 B;  3BUP A;  3M77 A;  3MI6 A;  3QXQ A;  4D72 A;  5A1A A;  1D8D B;  3ANI A;  4BZG A;  3G6J B;  2OOV A;  2WII B;  3D4Z A;  3BS6 A;  1TF4 A;  1OJM A;  1H37 A;  3GZK A;  1F9O A;  1KKT A;  1N22 A;  3VD5 A;  1NC5 A;  2V3N A;  3DYM A;  1N4Q B;  1QAK A;  1KZP B; 
#chains in the Genus database with same CATH homology
 3TY1 A;  3CZJ A;  3VD7 A;  1X1H A;  3BGA A;  1LF6 A;  4MMI A;  1NSM A;  3VDA A;  3VD9 A;  1MMZ A;  3SEP A;  4BZH A;  2JKE A;  1JZ3 A;  1JZ6 A;  1OJO A;  3T2Q A;  1NS2 A;  3VSN A;  3NRE A;  3J7H A;  3NNB A;  4BZE A;  1I8Q A;  1N7Q A;  2HTA A;  1RWG A;  1HMU A;  4J5T A;  4TTG A;  3VDC A;  2E22 A;  2CIS A;  4OK2 A;  4D6F A;  1X1J A;  1EGU A;  1K1X A;  4D6E A;  1RWA A;  3T09 A;  4FNV A;  2XSG A;  1HN0 A;  1LXM A;  2BRV X;  1Z45 A;  3MV1 1;  3T0A A;  4OZW A;  1MMY A;  1NS4 A;  1JZ2 A;  1HM3 A;  1UG9 A;  1NS7 A;  1DP0 A;  1JYX A;  2WCO A;  4NEI A;  3MWX A;  3MUZ 1;  1RW9 A;  1W3Y A;  1HMW A;  2WW2 A;  1JZ4 A;  2WMH A;  5E1Q A;  1JYW A;  1LUR A;  3VD4 A;  2WMK A;  2CIQ A;  3DCD A;  1SNZ A;  2WMF A;  2JKP A;  3NJX A;  3OS7 A;  2WZS A;  4AQ0 A;  2ZXQ A;  1F4A A;  1LOH A;  4MMH A;  1NKG A;  1PX3 A;  4DUW A;  1F9G A;  3E80 A;  1HN1 A;  4OJZ A;  1N7O A;  1LF9 A;  4F13 A;  2XHN A;  3NFV A;  2FUQ A;  5JMD A;  3I3E A;  3T2P A;  3IAQ A;  2WMJ A;  2BRW A;  3AFL A;  2WMI B;  3I3B A;  1MMU A;  4D6G A;  1X1I A;  3A24 A;  3I3D A;  2ZQ0 A;  3A0O A;  2WVX B;  2WW1 A;  1J0N A;  1N7R A;  3VSM A;  2WW3 A;  1J0M A;  3IAP A;  3K25 A;  1JYV A;  1NSZ A;  1RWF A;  3T08 A;  1JZ5 A;  1LXK A;  1C82 A;  4D6I A;  1TXK A;  3DYP A;  1JZ8 A;  2Q1F A;  4D71 A;  3OBA A;  2WVX A;  3T2O A;  1RWC A;  1OJP A;  1CB8 A;  1N7N A;  1MMX A;  2CIR A;  3BLC A;  3DYO A;  1F1S A;  4DUV A;  1YGA A;  1QAZ A;  2WMG A;  4D6H A;  2WMI A;  4DUX A;  1NSS A;  2E24 A;  1ULV A;  1N7P A;  1L7J A;  2JKA A;  4F10 A;  4D6J A;  1JZ7 A;  2WVY A;  1F4H A;  2D73 A;  1JOV A;  1NSV A;  1MN0 A;  4RNL A;  3VD3 A;  2WW0 A;  1HV6 A;  1HM2 A;  2HTB A;  2WDA A;  1L7K A;  1NS8 A;  3WFA A;  1NSR A;  3E1F 1;  1RWH A;  1OJN A;  1NSX A;  3DEC A;  3MUY 1;  3IMH A;  3MV0 1;  1PX4 A;  3T0B A;  3VDB A;  1K1W A;  1YQ2 A;  3T0D A;  3WVF A;  3ECQ A;  1SO0 A;  1NS0 A;  3OB8 A;  2X03 A;  4OZV A;  4D72 A;  2FUT A;  3Q1N A;  4D6D A;  5JMF A;  2WVZ A;  4D6C A;  4BZG A;  5A1A A;  3E7J A;  3BS6 A;  4E1Y A;  1OJM A;  3VD5 A;  1NSU A;  3NJV A;  1K1Y A;  3DYM A;  1JYN A;  4OK4 A;  4BZF A;  2BRP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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