1HM3A

Active site of chondroitinase ac lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis
Total Genus 245
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
245
sequence length
674
structure length
674
Chain Sequence
b'GTAELIMKRVMLDLKKPLRNMDKVAEKNLNTLQPDGSWKDVPYKDDAMTNWLPNNHLLQLETIIQAYIEKDSHYYGDDKVFDQISKAFKYWYDSDPKSRNWWHNEIATPQALGEMLILMRYGKKPLDEALVHKLTERMKRGEPEKKTGANKTDIALHYFYRALLTSDEALLSFAVKELFYPVQFVHYEEGLQYDYSYLQHGPQLQISSYGAVFITGVLKLANYVRDTPYALSTEKLAIFSKYYRDSYLKAIRGSYMDFNVEGRGVSRPDILNKKAEKKRLLVAKMIDLKHTEEWADAIARTDSTVAAGYKIEPYHHQFWNGDYVQHLRPAYSFNVRMVSKRTRRSESGNKENLLGRYLSDGATNIQLRGPEYYNIMPVWEWDKIPGITSRDYLTDRPLTKLWGEQGSNDFAGGVSDGVYGASAYALDYDSLQAKKAWFFFDKEIVCLGAGINSNAPENITTTLNQSWLNGPVISTAGKTGRGKITTFKAQGQFWLLHDAIGYYFPEGANLSLSTQSQKGNWFHINNSHSKDEVSGDVFKLWINHGARPENAQYAYIVLPGINKPEEIKKYNGTAPKVLANTNQLQAVYHQQLDMVQAIFYTAGKLSVAGIEIETDKPCAVLIKHINGKQVIWAADPLQKEKTAVLSIRDLKTGKTNRVKIDFPQQEFAGATVEL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords CHONDROITINASE AC
publication title Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
pubmed doi rcsb
source organism Pedobacter heparinus
molecule tags Lyase
total genus 245
structure length 674
sequence length 674
ec nomenclature ec 4.2.2.5: Chondroitin AC lyase.
pdb deposition date 2000-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1hm3A01
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1hm3A03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1hm3A02
3VD9A 1X1IA 3AFLA 5JMFA 1SNZA 1LURA 3E7JA 1N7PA 1C82A 1OJOA 1X1JA 2WMIB 3I3BA 3VD3A 1MMXA 4OZWA 3Q1NA 3DCDA 3NJXA 3NREA 3NNBA 1TXKA 3DECA 3ECQA 1EGUA 2WZSA 2BRPA 1W3YA 2CISA 3T0AA 4FNVA 3IAPA 3SEPA 1N7RA 2E22A 4F10A 3VDAA 1NSMA 2CIRA 3IAQA 1HMUA 3IMHA 3WFAA 4F13A 3T0BA 3E80A 1QAZA 3T08A 3T0DA 2WW1A 1ULVA 1F1SA 1JYVA 1NSZA 1UG9A 1LOHA 1YQ2A 2BRWA 3VDCA 1HMWA 2JKAA 1JZ2A 4MMIA 3A24A 2XSGA 2WW0A 2WMGA 4D6HA 4D6GA 3CZJA 3I3DA 1LF6A 3VD7A 1J0MA 5A1AA 3T2PA 4D71A 1HM3A 1K1XA 1L7KA 4D72A 1JYNA 4BZGA 3VDBA 3DYMA 3T2QA 2WVYA 4MMHA 1RWCA 1NSXA 4DUXA 1SO0A 2E24A 3VSMA 3BGAA 4BZEA 4D6EA 4E1YA 2X03A 1RWGA 2FUTA 2ZXQA 1MMUA 1OJNA 2JKPA 1F4AA 1YGAA 1K1YA 3OB8A 4OK4A 2BRVX 2Q1FA 1DP0A 1L7JA 2WMFA 3DYPA 2WMIA 1N7QA 4NEIA 1F4HA 1NSRA 3VSNA 1RWAA 1JZ5A 1JZ4A 1JYWA 2WCOA 4OZVA 2WMKA 1HN1A 1F9GA 1PX3A 1NS2A 1Z45A 2CIQA 4D6JA 2WW3A 1NSVA 2WVZA 1N7OA 3E1F1 3VD4A 2ZQ0A 1JZ3A 4BZHA 3NJVA 4D6CA 2D73A 2WVXA 1HN0A 1PX4A 3OS7A 3OBAA 4D6DA 1NS7A 3MWXA 3K25A 4BZFA 1MN0A 5JMDA 1NS8A 3MV01 1OJMA 1JOVA 1OJPA 1J0NA 3T09A 2WMHA 4DUWA 4DUVA 1LXKA 1JYXA 4D6IA 1NS4A 2FUQA 3A0OA 4OJZA 2HTBA 3MUY1 3MUZ1 1JZ8A 4TTGA 2WDAA 1RWHA 1NSUA 1NKGA 1I8QA 1LXMA 1NS0A 1JZ6A 3VD5A 1HV6A 1K1WA 3I3EA 4OK2A 2WVXB 3J7HA 1CB8A 1X1HA 5E1QA 4AQ0A 1MMZA 1JZ7A 4RNLA 2HTAA 2XHNA 4D6FA 3DYOA 1NSSA 3T2OA 2WW2A 3MV11 1RW9A 1MMYA 3NFVA 2JKEA 2WMJA 1HM2A 1N7NA 1LF9A 1RWFA
chains in the Genus database with same CATH superfamily
1X1IA 3AFLA 1O1TB 1JCRB 2A73B 1IS9A 3HXDB 3LVTA 3WUXA 3QDEA 3M7BA 1R33A 3RX7A 1KSIA 1KSCA 4KTRA 3DX1A 1N9AB 3X42A 2WMIB 3I3BA 2OKXA 1MMXA 3E33B 2XWBB 3KSQB 1D6ZA 3VD3A 3DCDA 3EJQA 4LNVA 3QFZA 3N0GA 3KLSA 3EJSA 1HXAA 3BVWA 3BLBA 3NREA 1KREA 5DGRA 3NNBA 5ILKA 3W5MA 3DX4A 1A2VA 2AHGA 1F9DA 3EU8A 3BUPA 4GTPB 4GTQB 1KS8A 4FNVA 2R2LB 1N24A 2E22A 1TF4A 2WY8A 1CLCA 3W7SA 3IAQA 1O6HA 4AYOA 1N94B 1DOGA 3RX8A 3E80A 2WW1A 1LVNA 3SDVA 1NSZA 5MEHA 1LOHA 2V3PA 4XUVA 2BRWA 3WVFA 1FAEA 3Q7FB 3VDCA 3X17A 4MMIA 5KKBA 1TQSA 4WVCA 1G87A 3DSWB 4D4BA 5A1AA 2YFNA 5CZLA 4UFCA 1HM3A 1K1XA 1L7KA 3M73A 4D72A 3HIIA 1PU4A 3K7XA 4YDEB 1W2ZA 1NSXA 2V8KA 1SO0A 1KWFA 1IA6A 2W0QA 2X03A 1C3DA 1L2AA 2F1AA 1H39A 2FUTA 3SDQA 3AMOA 1OJNA 3S4DA 1UI7A 1SIHA 5IL8A 4KTPA 2Y73A 3UD1A 3OB8A 2BB6A 2KXRA 1L7JA 3M00A 2H6IB 1JZ4A 1N7QA 4NEIA 1WMPA 2WMKA 5DHKA 1Z45A 2OQEA 1WU4A 1FP3A 2JJBA 3PZ2B 4BZHA 3OXUA 5ILDA 3P5PA 1HN0A 3W7UA 1PX4A 3OBAA 4BTWA 1NS7A 3MWXA 4Z4LA 1H35A 4FNTA 2J5CA 1JS4A 3BVVA 3KN4A 3P5RA 3QXFA 2YX9A 1FMIA 2A8ZA 2WMHA 1JYXA 1N4QB 4D6IA 2F7QA 3CZSA 3S4CA 4D94A 2HTBA 2OW6A 4TTGA 1SQCA 3S4AA 4Z4JA 3ANIA 4DODA 2F18A 2F7PA 1D6YA 3K5TA 4K3AA 1NS0A 3HXEB 3S9VA 3CU7A 1IVWA 2WOFA 4BTXA 4EV2A 5E1QA 3ANJA 1X1HA 1IVXA 2E2TA 1FPPB 2CFLA 4MU9A 3M75A 5EAUA 3T2OA 3BUBA 1RW9A 2WMJA 4LNGB 3QT3A 3MV01 1W6KA 2OOVA 1RWFA 1IQYA 4GTRB 2EAEA 1WMOA 1TN8B 1O1SB 3QWTA 3DX0A 1SNZA 1LURA 1GXOA 4D1JA 3SAEA 4V1RA 2FV0A 3BVUA 5KBPA 3EQAA 3VXDA 2FUZA 1RJOA 3Q1NA 4KKJA 5CA3A 3PZ3B 3NJXA 1AV4A 2QNOA 3ON6A 2XN2A 1QALA 1DL2A 1IQXA 1WU6A 4AYRA 4DLOA 4EL8A 1GAHA 3BVTA 2VN7A 2CQSA 3H3KA 3QG0A 3SEPA 1QX1A 1SPUA 3MI6A 3IMHA 4F13A 3T08A 1HCUA 4ONTA 4L6XA 3SDTA 2WYHA 3G6JB 4D1IA 1JYVA 1TNBB 3KBTC 2XFGA 3QT9A 1YQ2A 3ALAA 4KFDA 1HXGA 1GSZA 3HXCB 3A24A 2WW0A 2WYNA 2BB5A 4D6GA 3CZJA 1S64B 5M7YA 3BUQA 3CV5A 5FO7B 2WINB 3M72A 3E30B 3T33A 3T2PA 3VD7A 1H13A 3VDBA 1V7WA 3T2QA 3NBBA 2B4FA 3HXBB 4MMHA 2OQEC 3BS6A 2E24A 3VSMA 3PZ4B 1L1YA 4CE7A 1O1RB 2WIIB 4JJJA 4AYPA 3H2WA 3Q79B 3GZKA 3PYAA 1MMUA 1TQWA 2OW7A 2C11A 2JKPA 1FT2B 1PS3A 1HZFA 1F4AA 3M77A 1YGAA 5IK9A 1K1YA 4FNSA 4D4CA 2G02A 3PQIA 1GXMA 3PZ1B 1JZ5A 1FO2A 1GHQA 3D4ZA 3VSNA 1TNOB 2WCOA 4OZVA 2XQWA 2CIQA 1PX3A 3VD4A 5ILJA 2WY7A 4GTTB 4D4AA 3D5SA 2V8JA 2CFGA 1JZ3A 5IL3A 1O5MB 1N4RB 1H14A 1H3AA 1QQFA 2WVXA 3N0FA 3N9HA 3DDFA 3W7XA 2RDYA 5C05A 4D6DA 2CG1A 1MN0A 3X3XA 1OACA 2ONHA 5EASA 1FCEA 4MBGB 2CG0A 3DSTB 4FNUA 3DSSB 2H6HB 1KSDA 1LXKA 4DI5A 5AGDA 1RQ5A 2ZIRB 1TNZB 3PYBA 3GT5A 4FXGB 3A0OA 1JZ8A 4FNQA 2OOVC 1HWWA 2WDAA 1NKGA 1I8QA 4KFFA 3SFXB 2CWTA 3E6UA 4C1SA 1LXMA 1HTYA 4GAXA 2WGQA 3D3IA 2CFDA 1KZOB 3I3EA 4OK2A 1V5DA 2WVXB 2PNCA 4GL3A 4DLQA 1MMZA 1KZPB 3M01A 1IVUA 1TQVA 1X9DA 1FBOA 3WIWA 2XWJB 1MMYA 3DSXB 1AVLA 4K35A 3ACSA 1HM2A 3SQCA 4LIXA 3UD2A 3AMOB 3WKHA 1WU5A 1DYUA 2I07B 5JMFA 2G0DA 3E7JA 1OJOA 4GTOB 3Q73B 3MPHA 1MZCB 1X1JA 1G9JA 2ZZRA 1N22A 1S63B 1SIIA 3BUDA 5DGQA 3PMMA 3M74A 4OZWA 2GH4A 4ZH1A 3RX5A 4J5TA 3QFYA 1DCEB 4ZRPA 2GOXA 2DRSA 3SFYB 4FNRA 2F7OA 1TXKA 3ECQA 2WOHA 1EGUA 2DRQA 4V1SA 2ONGA 2WZSA 1W6CA 3EZ8A 4ZRQA 1AGMA 1GXNA 1K72A 3E34B 3KSLB 3Q78B 4GTVB 5IM1A 2XN0A 3IAPA 1TQTA 3RENA 4DOEA 4F10A 3VDAA 2WYIA 2CIRA 3DDGA 1HMUA 3A3VA 1WMNA 3T0DA 1ULVA 1N20A 2V8IA 1JRQA 1F1SA 5M7IA 3HI7A 1UG9A 2V3NA 3VW5A 1O7DD 1O6RA 1QBQB 4TXTA 3T0UA 1HMWA 1JZ2A 3OEDA 2XSGA 3Q75B 3DSVB 1LF6A 3WIQA 4CJ0A 4D71A 3W7TA 1V7VA 3U7VA 2P0VA 4RNQA 5IKAA 1SA5B 3EUVB 4BZGA 3DYMA 2EACA 5E2JA 3DPYB 1RWCA 1N21A 4DUXA 5DHIA 3EJPA 3CIHA 4M76A 2D5JA 3BGAA 4BZEA 2NOJA 4D6EA 3LZ9A 4E1YA 5CD2A 1JZ6A 3KQ4A 2Z07A 1RKYA 3D50A 2F0YB 1IU7A 1O6QA 4OK4A 2H6GB 2Q1FA 1G9GA 5FOBB 3DYPA 2WMIA 3BUIA 1AVKA 1TU5A 1RWAA 2FV1A 3RRSA 3CZNA 1R34A 1FT1B 1F9GA 1VD5A 1NS2A 2WW3A 1LTXB 4D6JA 1NSVA 2WVZA 1N7OA 1XWQA 3NJVA 4D6CA 3QRYA 3QXQA 3EU5B 1XW2A 4BZFA 5JMDA 4WVAA 1HXKA 3EJUA 1CEMA 3X3YA 3F59A 1J0NA 3D51A 1W5ZA 4D4DA 1TN6B 2GZ6A 3BVXA 4DUWA 3RJ3A 1TN7B 4DUVA 1UI8A 4OJZA 2NVPA 1NXCA 5JPNB 2ZL8A 2ZISB 2E2UA 2KXSA 3DX2A 1HXCA 3X3ZA 2BBCA 1F9OA 3DSUB 4EHMB 1HV6A 1K1WA 1US1A 3D4YA 3DX3A 3VD5A 3J7HA 4WVBA 3KBUC 1JZ7A 1D8DB 3EJTA 2HTAA 4YDOB 2XHNA 4D6FA 3DYOA 3E73A 1NSSA 4ZH5A 2ALWA 3W5NA 2AFAA 3NFVA 2ZBLA 2JKEA 3WA3A 4FUSA 1N4PB 1LF9A 2CQTA 3EJRA 2CWVA 3SDUA 3VD9A 1H37A 5IK6A 1NI1B 2BEDB 1GA2A 3NBJA 2DROA 3X40A 1N7PA 1C82A 4GTSB 1KKTA 4EV5A 2IEJB 1LD8B 3HIGA 1H54A 2PMVA 4Q2BA 1W6JA 2YFOA 2B39A 5JPMB 2RGKA 1HX9A 1TNUB 2H6FB 1UT9A 3DECA 2BRPA 3M7CA 1W3YA 2D1WA 2EABA 1H3CA 2CWUA 2CISA 3M7EA 3T0AA 3QPFA 2C10A 1FBWA 3TY1A 3KIIA 1N7RA 1NSMA 5ILYA 1H36A 5GZKA 3ANKA 1X81B 2FBAA 3PGBA 3WFAA 3T0BA 5FO9B 1QAZA 5ILIA 2D8LA 1LD7B 2CFWA 1KFGA 1H3BA 2JKAA 3QR8A 1TNYB 3M71A 1GLMA 2YIKA 3X41A 5FO8B 3M02A 1IA7A 3GLYA 2WMGA 4D6HA 3I3DA 4ZG8A 1J0MA 1G6IA 5IK0A 2CFKA 5EATA 3RSYA 1JYNA 4LNBB 3DRAB 2JG0A 2WVYA 3C72B 2RI8A 1W4NA 2Y74A 1R76A 4KFEA 2VN4A 1XWTA 4Q88A 1D6UA 4BOJA 3HXFB 1W7CA 2SQCA 4BTYA 1D8EB 1RWGA 2ZXQA 3QSPA 1GAIA 3BLCA 3S4BA 4AYQA 3WA2X 4BOKA 1NC5A 3Q7AB 3TF4A 3M78A 1KRFA 3AFJA 3SXXA 2BRVX 1SA4B 1DP0A 2WMFA 1QSJA 1IVVA 3ACTA 3SDRA 5GW7A 3WKGA 1N23A 1F4HA 1NSRA 2E2VA 1JYWA 2FYVA 4CJ1A 2AHFA 1HN1A 1EKMA 2DRRA 3E1F1 1JCSB 1QAFA 1TQUA 2RI9A 2ZQ0A 1N1ZA 3M7LA 3K11A 2D73A 3OS7A 1QWNA 3LOYA 2F1BA 3E32B 3K25A 3D5RA 1NS8A 5ILZA 1QAKA 1OJMA 2XN1A 1JOVA 1OJPA 3WC3A 2WO0A 4WU0A 2BT3A 3T09A 3M76A 1H12A 3G4FA 3SX1A 4QT9A 1NS4A 2FUQA 4TF4A 2F6DA 3MUY1 3MUZ1 3WKIA 1N9EA 4KKIA 5ILHA 1RWHA 3E37B 1NSUA 3H7LA 5IKHA 3D52A 1WZZA 1V7XA 4FJQA 1N1BA 2EADA 1QWUA 1O79A 4YCRA 3W7WA 1CB8A 2PN5A 1FO3A 1N4SB 1UMPA 4GTMB 4L0GA 4AQ0A 1V5CA 1AYXA 3WKFA 4FNPA 3G4DA 4FXKB 2JF4A 5GY3A 4RNLA 1W6GA 1N95B 2WW2A 2F7RA 3MV11 4L9PB 1JCQB 1NL4B 4D8OA 3P2CA 3WIRA 1N7NA
chains in the Genus database with same CATH topology
3VD9A 1X1IA 3AFLA 5JMFA 1SNZA 1LURA 3E7JA 1N7PA 1C82A 1OJOA 1X1JA 2WMIB 3I3BA 3VD3A 1MMXA 4OZWA 3Q1NA 3DCDA 4J5TA 3NJXA 3NREA 3NNBA 1TXKA 3DECA 3ECQA 1EGUA 2WZSA 2BRPA 1W3YA 2CISA 3T0AA 4FNVA 3IAPA 3TY1A 3SEPA 1N7RA 2E22A 4F10A 3VDAA 1NSMA 2CIRA 3IAQA 1HMUA 3IMHA 3WFAA 4F13A 3T0BA 3E80A 1QAZA 3T08A 3T0DA 2WW1A 1ULVA 1F1SA 1JYVA 1NSZA 1UG9A 1LOHA 1YQ2A 2BRWA 3WVFA 3VDCA 1HMWA 2JKAA 1JZ2A 4MMIA 3A24A 2XSGA 2WW0A 2WMGA 4D6HA 4D6GA 3CZJA 3I3DA 1LF6A 3VD7A 1J0MA 5A1AA 3T2PA 4D71A 1HM3A 1K1XA 1L7KA 4D72A 1JYNA 4BZGA 3VDBA 3DYMA 3T2QA 2WVYA 4MMHA 1RWCA 1NSXA 3BS6A 4DUXA 1SO0A 2E24A 3VSMA 3BGAA 4BZEA 4D6EA 4E1YA 2X03A 1RWGA 2FUTA 2ZXQA 1MMUA 1OJNA 2JKPA 3BLCA 1F4AA 1YGAA 1K1YA 3OB8A 4OK4A 2BRVX 2Q1FA 1DP0A 1L7JA 2WMFA 3DYPA 2WMIA 1N7QA 4NEIA 1F4HA 1NSRA 3VSNA 1RWAA 1JZ5A 1JZ4A 1JYWA 2WCOA 4OZVA 2WMKA 1HN1A 1F9GA 1PX3A 1NS2A 1Z45A 2CIQA 4D6JA 2WW3A 1NSVA 2WVZA 1N7OA 3E1F1 3VD4A 2ZQ0A 1JZ3A 4BZHA 3NJVA 4D6CA 2D73A 2WVXA 1HN0A 1PX4A 3OS7A 3OBAA 4D6DA 1NS7A 3MWXA 3K25A 4BZFA 1MN0A 5JMDA 1NS8A 3MV01 1OJMA 1JOVA 1OJPA 1J0NA 3T09A 2WMHA 4DUWA 4DUVA 1LXKA 1JYXA 4D6IA 1NS4A 2FUQA 3A0OA 4OJZA 2HTBA 3MUY1 3MUZ1 1JZ8A 4TTGA 2WDAA 1RWHA 1NSUA 1NKGA 1I8QA 1LXMA 1NS0A 1JZ6A 3VD5A 1HV6A 1K1WA 3I3EA 4OK2A 2WVXB 3J7HA 1CB8A 1X1HA 5E1QA 4AQ0A 1MMZA 1JZ7A 4RNLA 2HTAA 2XHNA 4D6FA 3DYOA 1NSSA 3T2OA 2WW2A 3MV11 1RW9A 1MMYA 3NFVA 2JKEA 2WMJA 1HM2A 1N7NA 1LF9A 1RWFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VD9 A;  1X1I A;  3AFL A;  5JMF A;  1SNZ A;  1LUR A;  3E7J A;  1N7P A;  1C82 A;  1OJO A;  1X1J A;  2WMI B;  3I3B A;  3VD3 A;  1MMX A;  4OZW A;  3Q1N A;  3DCD A;  3NJX A;  3NRE A;  3NNB A;  1TXK A;  3DEC A;  3ECQ A;  1EGU A;  2WZS A;  2BRP A;  1W3Y A;  2CIS A;  3T0A A;  4FNV A;  3IAP A;  3SEP A;  1N7R A;  2E22 A;  4F10 A;  3VDA A;  1NSM A;  2CIR A;  3IAQ A;  1HMU A;  3IMH A;  3WFA A;  4F13 A;  3T0B A;  3E80 A;  1QAZ A;  3T08 A;  3T0D A;  2WW1 A;  1ULV A;  1F1S A;  1JYV A;  1NSZ A;  1UG9 A;  1LOH A;  1YQ2 A;  2BRW A;  3VDC A;  1HMW A;  2JKA A;  1JZ2 A;  4MMI A;  3A24 A;  2XSG A;  2WW0 A;  2WMG A;  4D6H A;  4D6G A;  3CZJ A;  3I3D A;  1LF6 A;  3VD7 A;  1J0M A;  5A1A A;  3T2P A;  4D71 A;  1HM3 A;  1K1X A;  1L7K A;  4D72 A;  1JYN A;  4BZG A;  3VDB A;  3DYM A;  3T2Q A;  2WVY A;  4MMH A;  1RWC A;  1NSX A;  4DUX A;  1SO0 A;  2E24 A;  3VSM A;  3BGA A;  4BZE A;  4D6E A;  4E1Y A;  2X03 A;  1RWG A;  2FUT A;  2ZXQ A;  1MMU A;  1OJN A;  2JKP A;  1F4A A;  1YGA A;  1K1Y A;  3OB8 A;  4OK4 A;  2BRV X;  2Q1F A;  1DP0 A;  1L7J A;  2WMF A;  3DYP A;  2WMI A;  1N7Q A;  4NEI A;  1F4H A;  1NSR A;  3VSN A;  1RWA A;  1JZ5 A;  1JZ4 A;  1JYW A;  2WCO A;  4OZV A;  2WMK A;  1HN1 A;  1F9G A;  1PX3 A;  1NS2 A;  1Z45 A;  2CIQ A;  4D6J A;  2WW3 A;  1NSV A;  2WVZ A;  1N7O A;  3E1F 1;  3VD4 A;  2ZQ0 A;  1JZ3 A;  4BZH A;  3NJV A;  4D6C A;  2D73 A;  2WVX A;  1HN0 A;  1PX4 A;  3OS7 A;  3OBA A;  4D6D A;  1NS7 A;  3MWX A;  3K25 A;  4BZF A;  1MN0 A;  5JMD A;  1NS8 A;  3MV0 1;  1OJM A;  1JOV A;  1OJP A;  1J0N A;  3T09 A;  2WMH A;  4DUW A;  4DUV A;  1LXK A;  1JYX A;  4D6I A;  1NS4 A;  2FUQ A;  3A0O A;  4OJZ A;  2HTB A;  3MUY 1;  3MUZ 1;  1JZ8 A;  4TTG A;  2WDA A;  1RWH A;  1NSU A;  1NKG A;  1I8Q A;  1LXM A;  1NS0 A;  1JZ6 A;  3VD5 A;  1HV6 A;  1K1W A;  3I3E A;  4OK2 A;  2WVX B;  3J7H A;  1CB8 A;  1X1H A;  5E1Q A;  4AQ0 A;  1MMZ A;  1JZ7 A;  4RNL A;  2HTA A;  2XHN A;  4D6F A;  3DYO A;  1NSS A;  3T2O A;  2WW2 A;  3MV1 1;  1RW9 A;  1MMY A;  3NFV A;  2JKE A;  2WMJ A;  1HM2 A;  1N7N A;  1LF9 A;  1RWF A; 
#chains in the Genus database with same CATH topology
 1X1I A;  3AFL A;  1O1T B;  1JCR B;  2A73 B;  1IS9 A;  3HXD B;  3LVT A;  3WUX A;  3QDE A;  3M7B A;  1R33 A;  3RX7 A;  1KSI A;  1KSC A;  4KTR A;  3DX1 A;  1N9A B;  3X42 A;  2WMI B;  3I3B A;  2OKX A;  1MMX A;  3E33 B;  2XWB B;  3KSQ B;  1D6Z A;  3VD3 A;  3DCD A;  3EJQ A;  4LNV A;  3QFZ A;  3N0G A;  3KLS A;  3EJS A;  1HXA A;  3BVW A;  3BLB A;  3NRE A;  1KRE A;  5DGR A;  3NNB A;  5ILK A;  3W5M A;  3DX4 A;  1A2V A;  2AHG A;  1F9D A;  3EU8 A;  3BUP A;  4GTP B;  4GTQ B;  1KS8 A;  4FNV A;  2R2L B;  1N24 A;  2E22 A;  1TF4 A;  2WY8 A;  1CLC A;  3W7S A;  3IAQ A;  1O6H A;  4AYO A;  1N94 B;  1DOG A;  3RX8 A;  3E80 A;  2WW1 A;  1LVN A;  3SDV A;  1NSZ A;  5MEH A;  1LOH A;  2V3P A;  4XUV A;  2BRW A;  3WVF A;  1FAE A;  3Q7F B;  3VDC A;  3X17 A;  4MMI A;  5KKB A;  1TQS A;  4WVC A;  1G87 A;  3DSW B;  4D4B A;  5A1A A;  2YFN A;  5CZL A;  4UFC A;  1HM3 A;  1K1X A;  1L7K A;  3M73 A;  4D72 A;  3HII A;  1PU4 A;  3K7X A;  4YDE B;  1W2Z A;  1NSX A;  2V8K A;  1SO0 A;  1KWF A;  1IA6 A;  2W0Q A;  2X03 A;  1C3D A;  1L2A A;  2F1A A;  1H39 A;  2FUT A;  3SDQ A;  3AMO A;  1OJN A;  3S4D A;  1UI7 A;  1SIH A;  5IL8 A;  4KTP A;  2Y73 A;  3UD1 A;  3OB8 A;  2BB6 A;  2KXR A;  1L7J A;  3M00 A;  2H6I B;  1JZ4 A;  1N7Q A;  4NEI A;  1WMP A;  2WMK A;  5DHK A;  1Z45 A;  2OQE A;  1WU4 A;  1FP3 A;  2JJB A;  3PZ2 B;  4BZH A;  3OXU A;  5ILD A;  3P5P A;  1HN0 A;  3W7U A;  1PX4 A;  3OBA A;  4BTW A;  1NS7 A;  3MWX A;  4Z4L A;  1H35 A;  4FNT A;  2J5C A;  1JS4 A;  3BVV A;  3KN4 A;  3P5R A;  3QXF A;  2YX9 A;  1FMI A;  2A8Z A;  2WMH A;  1JYX A;  1N4Q B;  4D6I A;  2F7Q A;  3CZS A;  3S4C A;  4D94 A;  2HTB A;  2OW6 A;  4TTG A;  1SQC A;  3S4A A;  4Z4J A;  3ANI A;  4DOD A;  2F18 A;  2F7P A;  1D6Y A;  3K5T A;  4K3A A;  1NS0 A;  3HXE B;  3S9V A;  3CU7 A;  1IVW A;  2WOF A;  4BTX A;  4EV2 A;  5E1Q A;  3ANJ A;  1X1H A;  1IVX A;  2E2T A;  1FPP B;  2CFL A;  4MU9 A;  3M75 A;  5EAU A;  3T2O A;  3BUB A;  1RW9 A;  2WMJ A;  4LNG B;  3QT3 A;  3MV0 1;  1W6K A;  2OOV A;  1RWF A;  1IQY A;  4GTR B;  2EAE A;  1WMO A;  1TN8 B;  1O1S B;  3QWT A;  3DX0 A;  1SNZ A;  1LUR A;  1GXO A;  4D1J A;  3SAE A;  4V1R A;  2FV0 A;  3BVU A;  5KBP A;  3EQA A;  3VXD A;  2FUZ A;  1RJO A;  3Q1N A;  4KKJ A;  5CA3 A;  3PZ3 B;  3NJX A;  1AV4 A;  2QNO A;  3ON6 A;  2XN2 A;  1QAL A;  1DL2 A;  1IQX A;  1WU6 A;  4AYR A;  4DLO A;  4EL8 A;  1GAH A;  3BVT A;  2VN7 A;  2CQS A;  3H3K A;  3QG0 A;  3SEP A;  1QX1 A;  1SPU A;  3MI6 A;  3IMH A;  4F13 A;  3T08 A;  1HCU A;  4ONT A;  4L6X A;  3SDT A;  2WYH A;  3G6J B;  4D1I A;  1JYV A;  1TNB B;  3KBT C;  2XFG A;  3QT9 A;  1YQ2 A;  3ALA A;  4KFD A;  1HXG A;  1GSZ A;  3HXC B;  3A24 A;  2WW0 A;  2WYN A;  2BB5 A;  4D6G A;  3CZJ A;  1S64 B;  5M7Y A;  3BUQ A;  3CV5 A;  5FO7 B;  2WIN B;  3M72 A;  3E30 B;  3T33 A;  3T2P A;  3VD7 A;  1H13 A;  3VDB A;  1V7W A;  3T2Q A;  3NBB A;  2B4F A;  3HXB B;  4MMH A;  2OQE C;  3BS6 A;  2E24 A;  3VSM A;  3PZ4 B;  1L1Y A;  4CE7 A;  1O1R B;  2WII B;  4JJJ A;  4AYP A;  3H2W A;  3Q79 B;  3GZK A;  3PYA A;  1MMU A;  1TQW A;  2OW7 A;  2C11 A;  2JKP A;  1FT2 B;  1PS3 A;  1HZF A;  1F4A A;  3M77 A;  1YGA A;  5IK9 A;  1K1Y A;  4FNS A;  4D4C A;  2G02 A;  3PQI A;  1GXM A;  3PZ1 B;  1JZ5 A;  1FO2 A;  1GHQ A;  3D4Z A;  3VSN A;  1TNO B;  2WCO A;  4OZV A;  2XQW A;  2CIQ A;  1PX3 A;  3VD4 A;  5ILJ A;  2WY7 A;  4GTT B;  4D4A A;  3D5S A;  2V8J A;  2CFG A;  1JZ3 A;  5IL3 A;  1O5M B;  1N4R B;  1H14 A;  1H3A A;  1QQF A;  2WVX A;  3N0F A;  3N9H A;  3DDF A;  3W7X A;  2RDY A;  5C05 A;  4D6D A;  2CG1 A;  1MN0 A;  3X3X A;  1OAC A;  2ONH A;  5EAS A;  1FCE A;  4MBG B;  2CG0 A;  3DST B;  4FNU A;  3DSS B;  2H6H B;  1KSD A;  1LXK A;  4DI5 A;  5AGD A;  1RQ5 A;  2ZIR B;  1TNZ B;  3PYB A;  3GT5 A;  4FXG B;  3A0O A;  1JZ8 A;  4FNQ A;  2OOV C;  1HWW A;  2WDA A;  1NKG A;  1I8Q A;  4KFF A;  3SFX B;  2CWT A;  3E6U A;  4C1S A;  1LXM A;  1HTY A;  4GAX A;  2WGQ A;  3D3I A;  2CFD A;  1KZO B;  3I3E A;  4OK2 A;  1V5D A;  2WVX B;  2PNC A;  4GL3 A;  4DLQ A;  1MMZ A;  1KZP B;  3M01 A;  1IVU A;  1TQV A;  1X9D A;  1FBO A;  3WIW A;  2XWJ B;  1MMY A;  3DSX B;  1AVL A;  4K35 A;  3ACS A;  1HM2 A;  3SQC A;  4LIX A;  3UD2 A;  3AMO B;  3WKH A;  1WU5 A;  1DYU A;  2I07 B;  5JMF A;  2G0D A;  3E7J A;  1OJO A;  4GTO B;  3Q73 B;  3MPH A;  1MZC B;  1X1J A;  1G9J A;  2ZZR A;  1N22 A;  1S63 B;  1SII A;  3BUD A;  5DGQ A;  3PMM A;  3M74 A;  4OZW A;  2GH4 A;  4ZH1 A;  3RX5 A;  4J5T A;  3QFY A;  1DCE B;  4ZRP A;  2GOX A;  2DRS A;  3SFY B;  4FNR A;  2F7O A;  1TXK A;  3ECQ A;  2WOH A;  1EGU A;  2DRQ A;  4V1S A;  2ONG A;  2WZS A;  1W6C A;  3EZ8 A;  4ZRQ A;  1AGM A;  1GXN A;  1K72 A;  3E34 B;  3KSL B;  3Q78 B;  4GTV B;  5IM1 A;  2XN0 A;  3IAP A;  1TQT A;  3REN A;  4DOE A;  4F10 A;  3VDA A;  2WYI A;  2CIR A;  3DDG A;  1HMU A;  3A3V A;  1WMN A;  3T0D A;  1ULV A;  1N20 A;  2V8I A;  1JRQ A;  1F1S A;  5M7I A;  3HI7 A;  1UG9 A;  2V3N A;  3VW5 A;  1O7D D;  1O6R A;  1QBQ B;  4TXT A;  3T0U A;  1HMW A;  1JZ2 A;  3OED A;  2XSG A;  3Q75 B;  3DSV B;  1LF6 A;  3WIQ A;  4CJ0 A;  4D71 A;  3W7T A;  1V7V A;  3U7V A;  2P0V A;  4RNQ A;  5IKA A;  1SA5 B;  3EUV B;  4BZG A;  3DYM A;  2EAC A;  5E2J A;  3DPY B;  1RWC A;  1N21 A;  4DUX A;  5DHI A;  3EJP A;  3CIH A;  4M76 A;  2D5J A;  3BGA A;  4BZE A;  2NOJ A;  4D6E A;  3LZ9 A;  4E1Y A;  5CD2 A;  1JZ6 A;  3KQ4 A;  2Z07 A;  1RKY A;  3D50 A;  2F0Y B;  1IU7 A;  1O6Q A;  4OK4 A;  2H6G B;  2Q1F A;  1G9G A;  5FOB B;  3DYP A;  2WMI A;  3BUI A;  1AVK A;  1TU5 A;  1RWA A;  2FV1 A;  3RRS A;  3CZN A;  1R34 A;  1FT1 B;  1F9G A;  1VD5 A;  1NS2 A;  2WW3 A;  1LTX B;  4D6J A;  1NSV A;  2WVZ A;  1N7O A;  1XWQ A;  3NJV A;  4D6C A;  3QRY A;  3QXQ A;  3EU5 B;  1XW2 A;  4BZF A;  5JMD A;  4WVA A;  1HXK A;  3EJU A;  1CEM A;  3X3Y A;  3F59 A;  1J0N A;  3D51 A;  1W5Z A;  4D4D A;  1TN6 B;  2GZ6 A;  3BVX A;  4DUW A;  3RJ3 A;  1TN7 B;  4DUV A;  1UI8 A;  4OJZ A;  2NVP A;  1NXC A;  5JPN B;  2ZL8 A;  2ZIS B;  2E2U A;  2KXS A;  3DX2 A;  1HXC A;  3X3Z A;  2BBC A;  1F9O A;  3DSU B;  4EHM B;  1HV6 A;  1K1W A;  1US1 A;  3D4Y A;  3DX3 A;  3VD5 A;  3J7H A;  4WVB A;  3KBU C;  1JZ7 A;  1D8D B;  3EJT A;  2HTA A;  4YDO B;  2XHN A;  4D6F A;  3DYO A;  3E73 A;  1NSS A;  4ZH5 A;  2ALW A;  3W5N A;  2AFA A;  3NFV A;  2ZBL A;  2JKE A;  3WA3 A;  4FUS A;  1N4P B;  1LF9 A;  2CQT A;  3EJR A;  2CWV A;  3SDU A;  3VD9 A;  1H37 A;  5IK6 A;  1NI1 B;  2BED B;  1GA2 A;  3NBJ A;  2DRO A;  3X40 A;  1N7P A;  1C82 A;  4GTS B;  1KKT A;  4EV5 A;  2IEJ B;  1LD8 B;  3HIG A;  1H54 A;  2PMV A;  4Q2B A;  1W6J A;  2YFO A;  2B39 A;  5JPM B;  2RGK A;  1HX9 A;  1TNU B;  2H6F B;  1UT9 A;  3DEC A;  2BRP A;  3M7C A;  1W3Y A;  2D1W A;  2EAB A;  1H3C A;  2CWU A;  2CIS A;  3M7E A;  3T0A A;  3QPF A;  2C10 A;  1FBW A;  3TY1 A;  3KII A;  1N7R A;  1NSM A;  5ILY A;  1H36 A;  5GZK A;  3ANK A;  1X81 B;  2FBA A;  3PGB A;  3WFA A;  3T0B A;  5FO9 B;  1QAZ A;  5ILI A;  2D8L A;  1LD7 B;  2CFW A;  1KFG A;  1H3B A;  2JKA A;  3QR8 A;  1TNY B;  3M71 A;  1GLM A;  2YIK A;  3X41 A;  5FO8 B;  3M02 A;  1IA7 A;  3GLY A;  2WMG A;  4D6H A;  3I3D A;  4ZG8 A;  1J0M A;  1G6I A;  5IK0 A;  2CFK A;  5EAT A;  3RSY A;  1JYN A;  4LNB B;  3DRA B;  2JG0 A;  2WVY A;  3C72 B;  2RI8 A;  1W4N A;  2Y74 A;  1R76 A;  4KFE A;  2VN4 A;  1XWT A;  4Q88 A;  1D6U A;  4BOJ A;  3HXF B;  1W7C A;  2SQC A;  4BTY A;  1D8E B;  1RWG A;  2ZXQ A;  3QSP A;  1GAI A;  3BLC A;  3S4B A;  4AYQ A;  3WA2 X;  4BOK A;  1NC5 A;  3Q7A B;  3TF4 A;  3M78 A;  1KRF A;  3AFJ A;  3SXX A;  2BRV X;  1SA4 B;  1DP0 A;  2WMF A;  1QSJ A;  1IVV A;  3ACT A;  3SDR A;  5GW7 A;  3WKG A;  1N23 A;  1F4H A;  1NSR A;  2E2V A;  1JYW A;  2FYV A;  4CJ1 A;  2AHF A;  1HN1 A;  1EKM A;  2DRR A;  3E1F 1;  1JCS B;  1QAF A;  1TQU A;  2RI9 A;  2ZQ0 A;  1N1Z A;  3M7L A;  3K11 A;  2D73 A;  3OS7 A;  1QWN A;  3LOY A;  2F1B A;  3E32 B;  3K25 A;  3D5R A;  1NS8 A;  5ILZ A;  1QAK A;  1OJM A;  2XN1 A;  1JOV A;  1OJP A;  3WC3 A;  2WO0 A;  4WU0 A;  2BT3 A;  3T09 A;  3M76 A;  1H12 A;  3G4F A;  3SX1 A;  4QT9 A;  1NS4 A;  2FUQ A;  4TF4 A;  2F6D A;  3MUY 1;  3MUZ 1;  3WKI A;  1N9E A;  4KKI A;  5ILH A;  1RWH A;  3E37 B;  1NSU A;  3H7L A;  5IKH A;  3D52 A;  1WZZ A;  1V7X A;  4FJQ A;  1N1B A;  2EAD A;  1QWU A;  1O79 A;  4YCR A;  3W7W A;  1CB8 A;  2PN5 A;  1FO3 A;  1N4S B;  1UMP A;  4GTM B;  4L0G A;  4AQ0 A;  1V5C A;  1AYX A;  3WKF A;  4FNP A;  3G4D A;  4FXK B;  2JF4 A;  5GY3 A;  4RNL A;  1W6G A;  1N95 B;  2WW2 A;  2F7R A;  3MV1 1;  4L9P B;  1JCQ B;  1NL4 B;  4D8O A;  3P2C A;  3WIR A;  1N7N A; 
#chains in the Genus database with same CATH homology
 3VD9 A;  1X1I A;  3AFL A;  5JMF A;  1SNZ A;  1LUR A;  3E7J A;  1N7P A;  1C82 A;  1OJO A;  1X1J A;  2WMI B;  3I3B A;  3VD3 A;  1MMX A;  4OZW A;  3Q1N A;  3DCD A;  4J5T A;  3NJX A;  3NRE A;  3NNB A;  1TXK A;  3DEC A;  3ECQ A;  1EGU A;  2WZS A;  2BRP A;  1W3Y A;  2CIS A;  3T0A A;  4FNV A;  3IAP A;  3TY1 A;  3SEP A;  1N7R A;  2E22 A;  4F10 A;  3VDA A;  1NSM A;  2CIR A;  3IAQ A;  1HMU A;  3IMH A;  3WFA A;  4F13 A;  3T0B A;  3E80 A;  1QAZ A;  3T08 A;  3T0D A;  2WW1 A;  1ULV A;  1F1S A;  1JYV A;  1NSZ A;  1UG9 A;  1LOH A;  1YQ2 A;  2BRW A;  3WVF A;  3VDC A;  1HMW A;  2JKA A;  1JZ2 A;  4MMI A;  3A24 A;  2XSG A;  2WW0 A;  2WMG A;  4D6H A;  4D6G A;  3CZJ A;  3I3D A;  1LF6 A;  3VD7 A;  1J0M A;  5A1A A;  3T2P A;  4D71 A;  1HM3 A;  1K1X A;  1L7K A;  4D72 A;  1JYN A;  4BZG A;  3VDB A;  3DYM A;  3T2Q A;  2WVY A;  4MMH A;  1RWC A;  1NSX A;  3BS6 A;  4DUX A;  1SO0 A;  2E24 A;  3VSM A;  3BGA A;  4BZE A;  4D6E A;  4E1Y A;  2X03 A;  1RWG A;  2FUT A;  2ZXQ A;  1MMU A;  1OJN A;  2JKP A;  3BLC A;  1F4A A;  1YGA A;  1K1Y A;  3OB8 A;  4OK4 A;  2BRV X;  2Q1F A;  1DP0 A;  1L7J A;  2WMF A;  3DYP A;  2WMI A;  1N7Q A;  4NEI A;  1F4H A;  1NSR A;  3VSN A;  1RWA A;  1JZ5 A;  1JZ4 A;  1JYW A;  2WCO A;  4OZV A;  2WMK A;  1HN1 A;  1F9G A;  1PX3 A;  1NS2 A;  1Z45 A;  2CIQ A;  4D6J A;  2WW3 A;  1NSV A;  2WVZ A;  1N7O A;  3E1F 1;  3VD4 A;  2ZQ0 A;  1JZ3 A;  4BZH A;  3NJV A;  4D6C A;  2D73 A;  2WVX A;  1HN0 A;  1PX4 A;  3OS7 A;  3OBA A;  4D6D A;  1NS7 A;  3MWX A;  3K25 A;  4BZF A;  1MN0 A;  5JMD A;  1NS8 A;  3MV0 1;  1OJM A;  1JOV A;  1OJP A;  1J0N A;  3T09 A;  2WMH A;  4DUW A;  4DUV A;  1LXK A;  1JYX A;  4D6I A;  1NS4 A;  2FUQ A;  3A0O A;  4OJZ A;  2HTB A;  3MUY 1;  3MUZ 1;  1JZ8 A;  4TTG A;  2WDA A;  1RWH A;  1NSU A;  1NKG A;  1I8Q A;  1LXM A;  1NS0 A;  1JZ6 A;  3VD5 A;  1HV6 A;  1K1W A;  3I3E A;  4OK2 A;  2WVX B;  3J7H A;  1CB8 A;  1X1H A;  5E1Q A;  4AQ0 A;  1MMZ A;  1JZ7 A;  4RNL A;  2HTA A;  2XHN A;  4D6F A;  3DYO A;  1NSS A;  3T2O A;  2WW2 A;  3MV1 1;  1RW9 A;  1MMY A;  3NFV A;  2JKE A;  2WMJ A;  1HM2 A;  1N7N A;  1LF9 A;  1RWF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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