1OJMA

Specificity and mechanism of streptococcus pneumoniae hyaluronate lyase: complex with unsulphated chondroitin disaccharide
Total Genus 259
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
259
sequence length
721
structure length
721
Chain Sequence
b'VKDTYTDRLDDWNGIIAGNQYYDSKNDQMAKLNQELEGKVADSLSSISSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEWMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPEHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFYQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPLLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQSDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFGLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTETDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLGSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSKKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYMLIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLKRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords HYALURONATE LYASE
publication title Structures of Streptococcus Pneumoniae Hyaluronate Lyase in Complex with Chondroitin and Chondroitin Sulfate Disaccharides: Insights Into Specificity and Mechanism of Action
pubmed doi rcsb
source organism Streptococcus pneumoniae
molecule tags Lyase
total genus 259
structure length 721
sequence length 721
ec nomenclature ec 4.2.2.1: Hyaluronate lyase.
pdb deposition date 2003-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02278 Lyase_8 Polysaccharide lyase family 8, super-sandwich domain
A PF02884 Lyase_8_C Polysaccharide lyase family 8, C-terminal beta-sandwich domain
A PF08124 Lyase_8_N Polysaccharide lyase family 8, N terminal alpha-helical domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.50.10.100 Mainly Alpha Alpha/alpha barrel Glycosyltransferase Chondroitin AC/alginate lyase 1ojmA02
2.60.220.10 Mainly Beta Sandwich Chondroitinase Ac; Chain A, domain 3 Polysaccharide lyase family 8-like, C-terminal 1ojmA03
2.70.98.10 Mainly Beta Distorted Sandwich Beta-galactosidase; Chain A, domain 5 Beta-galactosidase; Chain A, domain 5 1ojmA01
3AFLA 1N7PA 1HV6A 1N7RA 5JMDA 2WW0A 3T0AA 3VDCA 3J7HA 1N7OA 1NS0A 1JZ2A 2WMIA 1K1WA 2XSGA 1K1XA 1PX4A 3VD4A 1F4AA 1LF9A 1N7NA 3NNBA 2ZQ0A 2E22A 3T0BA 1NS2A 2WVZA 3VD9A 1X1HA 2WCOA 4D6DA 1JZ8A 1J0NA 3E7JA 1L7JA 1L7KA 4DUVA 4BZFA 4F13A 1OJMA 1N7QA 2BRVX 3IMHA 4D71A 2WW2A 3T2PA 2FUQA 1YGAA 1JZ5A 4OK2A 5JMFA 2JKPA 1X1JA 1JYXA 4BZHA 2WW1A 3T2QA 3VD5A 1MMUA 1HMUA 3T08A 4BZGA 3E80A 4AQ0A 1OJNA 3ECQA 1SNZA 2WMIB 1JZ4A 1NS8A 1LURA 2HTBA 3VSMA 3VDAA 2X03A 4D6IA 2WMJA 4DUXA 3MWXA 1NSUA 3A0OA 4OJZA 3T09A 4RNLA 1NSMA 4OZVA 1W3YA 1PX3A 3IAQA 2BRPA 1MN0A 1RWCA 3Q1NA 1F9GA 2FUTA 1J0MA 4D72A 4D6FA 1JOVA 3OB8A 2E24A 1HMWA 1HN0A 3VD7A 4E1YA 1NSRA 3IAPA 4D6GA 1Z45A 3MV11 1HN1A 1JZ3A 3BGAA 3VDBA 1NS7A 1RW9A 3I3DA 1HM2A 1RWGA 1CB8A 4F10A 1RWFA 3MV01 3DYPA 1JZ7A 3NFVA 2XHNA 2WVYA 1X1IA 2JKEA 3K25A 1JYWA 4MMIA 2WVXA 1LOHA 1MMZA 1NSSA 5E1QA 1MMYA 1EGUA 2HTAA 1RWAA 4NEIA 1TXKA 2WW3A 1C82A 3MUY1 3MUZ1 1JYVA 3NJVA 1NSXA 1LXMA 2CIQA 1MMXA 3DCDA 3DYMA 3OBAA 1JZ6A 3I3BA 1LF6A 2CISA 4MMHA 1OJPA 1NSZA 2JKAA 2WMGA 3A24A 1QAZA 2WMKA 2WMFA 3NJXA 4D6EA 1I8QA 1UG9A 3DECA 3NREA 3WFAA 3VSNA 3I3EA 1DP0A 3SEPA 2WZSA 2WMHA 1ULVA 3E1F1 2CIRA 2WVXB 3OS7A 4BZEA 1JYNA 1F1SA 2BRWA 3DYOA 1F4HA 4TTGA 1SO0A 1NKGA 1NSVA 2Q1FA 4OK4A 4OZWA 2ZXQA 4DUWA 1OJOA 1NS4A 1LXKA 4D6JA 4D6HA 2D73A 4D6CA 2WDAA 1YQ2A 4FNVA 1K1YA 5A1AA 3CZJA 3T2OA 1RWHA 3T0DA 1HM3A 3VD3A
chains in the Genus database with same CATH superfamily
4LNBB 3HXFB 5JMDA 3VDCA 3J7HA 1HXGA 1NS0A 5EAUA 2RGKA 2E2TA 3OEDA 2F1BA 3DSTB 1LF9A 3T09A 2YFNA 5IK9A 2F7OA 5JPNB 3CZSA 3WIQA 4ZRQA 3P5RA 2WOHA 1FCEA 2R2LB 1TQUA 3LOYA 1X1HA 2WGQA 4DLQA 1J0NA 1HZFA 4AYRA 4F13A 1OJMA 1JS4A 2BRVX 4MBGB 3W5NA 3MPHA 1FO3A 2GOXA 3DPYB 4FUSA 3SFXB 2CFKA 5IKAA 1L1YA 1MMUA 1HMUA 3BS6A 5CZLA 1TU5A 3NBBA 2H6IB 2EACA 1OJNA 3ECQA 2XN1A 4ZH5A 1SNZA 4D1IA 2CWUA 3Q7FB 3RJ3A 1RJOA 1KS8A 1NS8A 1QAKA 1US1A 4D6IA 2V8IA 1IVWA 3A0OA 1TN6B 2B4FA 3QT3A 2BBCA 5JPMB 3KBTC 1MZCB 1TF4A 2DRSA 1NSMA 3BUIA 3EJRA 4GTTB 2C10A 1F9GA 2PMVA 2WY7A 1W5ZA 2H6FB 3SFYB 1NSRA 2BB6A 3HXDB 2F18A 1NI1B 3AMOA 1RW9A 3D3IA 3HXCB 2AHFA 3SDTA 1CB8A 1RWFA 3QXFA 2CQSA 2FV0A 3CV5A 1X1IA 2JG0A 3E6UA 3DSWB 4QT9A 3Q7AB 4CJ1A 3M7EA 4TF4A 3RX8A 4KTPA 4DLOA 1N95B 2ZL8A 5DGRA 2NVPA 2WW3A 1O1TB 1JYVA 3NJVA 1N21A 4KKIA 3M78A 1O6RA 2G0DA 1LXMA 2WOFA 2CIQA 4ZRPA 1FT2B 2F6DA 1JZ6A 2EADA 4Z4JA 3DDFA 3HIGA 3AMOB 1PS3A 2JKAA 5DHKA 1HXCA 3QFYA 2WMGA 3M00A 1G9JA 2FV1A 4D6EA 2A73B 4FNTA 1I8QA 3DECA 3DX0A 3WFAA 1HXKA 1KKTA 3I3EA 3GT5A 2XFGA 4GTRB 3W7WA 2KXSA 4XUVA 3BVTA 2DRQA 5IL3A 3DYOA 1SO0A 1S64B 2ZBLA 4GTPB 4DI5A 4OK4A 4EHMB 4Q88A 2ZXQA 1N1BA 2CG1A 3SQCA 1AYXA 4J5TA 4YCRA 1QALA 5FOBB 1G9GA 3KSQB 1JCRB 4FJQA 1N4SB 5ILYA 1K1YA 3DX1A 3WA3A 3PYAA 2RI8A 5EASA 5CD2A 3CZJA 3T0UA 3KSLB 4BTWA 3E32B 2BB5A 3M7BA 1HV6A 1N7RA 3D52A 2WY8A 2XSGA 3QG0A 1K1XA 3WA2X 4WVBA 3VD4A 3TF4A 1H3AA 1QBQB 3GZKA 2ZQ0A 2PNCA 3F59A 1QSJA 2OQEC 2OW6A 2J5CA 2WVZA 4WU0A 5FO9B 3ON6A 3WIRA 4K3AA 1JZ8A 2DRRA 3E7JA 1H39A 4EV5A 4BZFA 4EV2A 3X42A 3IMHA 4FNQA 5JMFA 2FBAA 2WW1A 4ZH1A 3QR8A 1TNOB 3ANIA 1H35A 3VW5A 1W2ZA 5IKHA 3E80A 1FMIA 2QNOA 3QPFA 4ONTA 3LVTA 4MU9A 1SA5B 2AHGA 2HTBA 3VDAA 5C05A 3RRSA 3BVUA 4DUXA 2XN0A 1NSUA 3MWXA 2OOVC 4CJ0A 3M71A 3RX7A 4OZVA 3BVWA 1PX3A 1C3DA 1JCSB 3ACTA 3EU8A 5FO7B 2YX9A 2RI9A 2FUTA 1KZOB 3M76A 3OB8A 1SIHA 4K35A 3X3XA 1NC5A 1FAEA 1W6CA 4E1YA 4AYPA 5KBPA 1N9AB 3SDUA 3IAPA 2EAEA 1Z45A 1SQCA 3S4DA 5M7IA 2D8LA 3S4AA 3BGAA 2H6HB 1JZ7A 3SXXA 3DYPA 3X3YA 3N9HA 3NFVA 4L9PB 2CFLA 2D5JA 1AVLA 2JKEA 3VXDA 3M73A 1F9OA 2WVYA 2XHNA 3WKGA 1LTXB 3WKFA 3WKIA 4MMIA 3BUQA 3D4YA 1NSSA 3DSVB 5E1QA 1G87A 5CA3A 1EGUA 1O79A 2HTAA 1QQFA 3OXUA 3W7XA 1O7DD 3E37B 2PN5A 2F7PA 3QT9A 1MMXA 2OQEA 3BUDA 1O1RB 1D8DB 3RENA 2V3PA 3SDQA 4UFCA 1TNZB 1N4PB 1HX9A 1FT1B 3H3KA 4D4AA 1O5MB 2WO0A 3M75A 2WMKA 3WIWA 3M01A 3QSPA 4BOKA 1UG9A 1R33A 3NREA 3W7SA 2YIKA 1V5CA 2WZSA 3U7VA 1ULVA 1NL4B 1JYNA 1F1SA 2JF4A 4LNVA 1TQSA 3Q73B 4BTXA 1F4HA 2F7QA 2Q1FA 2A8ZA 3W7UA 4OZWA 2RDYA 3SX1A 1AGMA 1TNUB 2H6GB 3QXQA 2OOVA 1IA6A 5IK0A 1NS4A 1TQWA 4RNQA 1UI7A 3D51A 4Z4LA 5GW7A 4L6XA 5A1AA 1GLMA 1N4RB 3DSSB 1IVUA 3T0DA 1HM3A 1V7XA 2E2UA 3VD3A 3AFLA 3S9VA 1TNYB 1DYUA 2WW0A 3T0AA 1N7OA 1JZ2A 4WVCA 3E30B 1D8EB 1K1WA 1PX4A 1SIIA 4GAXA 4DOEA 3HIIA 3BLCA 1N7NA 3NNBA 3QDEA 3E33B 2E22A 2WYNA 2ONHA 3T0BA 3WC3A 1H36A 3LZ9A 3E34B 2WCOA 2CFGA 1TQVA 3BVVA 5ILZA 1L7KA 4DUVA 2AFAA 3EQAA 3D50A 1DOGA 3PZ4B 1N7QA 5ILIA 4V1SA 1YGAA 1SPUA 4OK2A 4FXKB 2JKPA 1JYXA 1UMPA 2NOJA 4V1RA 1W6GA 3BUPA 3EJTA 3T2QA 1OACA 4BZHA 3T08A 1GHQA 1TN7B 3BLBA 4GTQB 5KKBA 3DRAB 1GAIA 2V3NA 2KXRA 5ILKA 2CG0A 4AQ0A 3N0FA 2ALWA 1D6ZA 3EJSA 2I07B 1TN8B 4FNUA 4ZG8A 3ACSA 1LURA 3VSMA 2X03A 2WIIB 1SA4B 2WMJA 4OJZA 2E2VA 3SAEA 2Y74A 3EJPA 2BRPA 1MN0A 3IAQA 1RWCA 3Q1NA 1HXAA 2XWJB 1JOVA 5AGDA 2E24A 1W6KA 3G6JB 1HN0A 3VD7A 3EJUA 3SDRA 1GXMA 4FNSA 2XWBB 5MEHA 1WMOA 3P5PA 4D6GA 3G4DA 1HN1A 1G6IA 2Z07A 2ZISB 3M02A 3D4ZA 3BUBA 1RWGA 5GY3A 1O6HA 1PU4A 1FBWA 1K72A 1H14A 3WVFA 1FP3A 1KWFA 3NBJA 2GH4A 2ZIRB 2DROA 3EUVB 4KFEA 1X9DA 1H37A 1HWWA 1MMZA 1GAHA 1MMYA 3KIIA 3MUY1 1RWAA 3C72B 1C82A 1VD5A 1CLCA 3EU5B 5IK6A 3PQIA 4YDEB 1UI8A 3DSXB 5DHIA 1NSXA 2V8JA 4D94A 3DX3A 3DCDA 3DYMA 1H3BA 3D5SA 2VN4A 2JJBA 3DDGA 3S4BA 1JRQA 2SQCA 1IQYA 4BOJA 4MMHA 2EABA 4LNGB 3A24A 1GA2A 5DGQA 3M72A 4L0GA 1DCEB 3VSNA 4DODA 3RSYA 4D4CA 1LVNA 5M7YA 1TQTA 2ZZRA 3D5RA 3H2WA 4GL3A 3RX5A 4AYQA 2WMHA 2CIRA 3E1F1 4C1SA 4BZEA 2BRWA 1V5DA 4AYOA 1WU4A 4TTGA 1H13A 1NKGA 2BT3A 4LIXA 3ANKA 1W7CA 1N94B 3GLYA 1QX1A 3CIHA 1LXKA 4D6JA 4D6HA 3K7XA 3CZNA 2D73A 1H54A 4BTYA 4D6CA 4WVAA 3QFZA 1YQ2A 3PZ3B 2WYHA 3T2OA 4D4BA 3WUXA 4GTSB 1KRFA 1WMNA 2CFWA 1FO2A 4GTMB 1N7PA 1WZZA 1FBOA 2WINB 5ILHA 3PZ1B 4KFDA 2WMIA 2GZ6A 4YDOB 1V7VA 4GTOB 5E2JA 3T33A 3E73A 1F4AA 2OW7A 2Y73A 1IQXA 3ANJA 3HXEB 3UD1A 1QAFA 3HXBB 1JCQB 1N1ZA 3WKHA 1NS2A 1UT9A 3QRYA 2CWVA 2P0VA 3AFJA 1S63B 4CE7A 4EL8A 3KBUC 3VD9A 4KKJA 4D6DA 1L7JA 1KZPB 1DL2A 3K11A 3Q78B 3M7CA 1QWNA 3PMMA 1XWTA 3A3VA 1HCUA 2F0YB 4D71A 2WW2A 2FUQA 3T2PA 1JZ5A 1D6UA 3P2CA 1X1JA 1N9EA 3X40A 2YFOA 2C11A 3VD5A 1IVVA 4BZGA 1LD7B 1W6JA 3KQ4A 4D8OA 1WMPA 5IL8A 5ILJA 2XN2A 2OKXA 2W0QA 2WMIB 4KTRA 4KFFA 1JZ4A 5FO8B 3KLSA 3W7TA 1N23A 2IEJB 1A2VA 1N22A 3X3ZA 1KREA 4GTVB 3MI6A 1GXNA 1X81B 1FPPB 3H7LA 1KSIA 1W3YA 2XQWA 4RNLA 3W5MA 3PYBA 3TY1A 3S4CA 1J0MA 1N4QB 4D6FA 2CQTA 1KSDA 3DSUB 1HMWA 1V7WA 4D72A 2D1WA 1N24A 4FNRA 3MV11 1JZ3A 3VDBA 1NXCA 3M74A 1XWQA 2V8KA 1HM2A 1NS7A 2ONGA 3I3DA 4F10A 3MV01 3SDVA 2FYVA 3K25A 2VN7A 3HI7A 1H3CA 3KN4A 2B39A 1JYWA 2WVXA 1LOHA 3BVXA 1TNBB 1D6YA 3Q79B 1AVKA 4D1JA 2CFDA 1O1SB 4NEIA 1TXKA 2CWTA 1N20A 3EJQA 3MUZ1 1IVXA 3CU7A 3PZ2B 2F1AA 1AV4A 1F9DA 1RQ5A 1IS9A 3OBAA 3N0GA 3QWTA 3I3BA 1LF6A 1IU7A 3X41A 1O6QA 1KFGA 1QWUA 1IA7A 2CISA 3M7LA 5GZKA 1OJPA 1KSCA 1NSZA 3ALAA 1WU6A 4D4DA 1QAZA 2F7RA 3UD2A 5ILDA 2WMFA 2BEDB 1GXOA 1L2AA 3NJXA 1XW2A 3K5TA 1W4NA 4TXTA 1R76A 1DP0A 3SEPA 3OS7A 1WU5A 2WVXB 4M76A 1CEMA 2WYIA 3X17A 4FNPA 2FUZA 3DX4A 3Q75B 1NSVA 1LD8B 1H12A 4DUWA 2G02A 3M77A 3G4FA 4JJJA 4Q2BA 1OJOA 1R34A 3PGBA 1HTYA 1GSZA 2WDAA 1RKYA 4FNVA 5EATA 1EKMA 5IM1A 1RWHA 3EZ8A 4FXGB 3DX2A
chains in the Genus database with same CATH topology
3AFLA 1N7PA 1HV6A 1N7RA 5JMDA 2WW0A 3T0AA 3VDCA 3J7HA 1N7OA 1NS0A 1JZ2A 2WMIA 1K1WA 2XSGA 1K1XA 1PX4A 3VD4A 1F4AA 1LF9A 3BLCA 1N7NA 3NNBA 2ZQ0A 2E22A 3T0BA 1NS2A 2WVZA 3VD9A 1X1HA 2WCOA 4D6DA 1JZ8A 1J0NA 3E7JA 1L7JA 1L7KA 4DUVA 4BZFA 4F13A 1OJMA 1N7QA 2BRVX 3IMHA 4D71A 2WW2A 3T2PA 2FUQA 1YGAA 1JZ5A 4OK2A 5JMFA 2JKPA 1X1JA 1JYXA 4BZHA 2WW1A 3T2QA 3VD5A 1MMUA 1HMUA 3T08A 3BS6A 4BZGA 3E80A 4AQ0A 1OJNA 3ECQA 1SNZA 2WMIB 1JZ4A 1NS8A 1LURA 2HTBA 3VSMA 3VDAA 2X03A 4D6IA 2WMJA 4DUXA 3MWXA 1NSUA 3A0OA 4OJZA 3T09A 4RNLA 1NSMA 4OZVA 1W3YA 1PX3A 3IAQA 2BRPA 1MN0A 3TY1A 1RWCA 3Q1NA 1F9GA 2FUTA 1J0MA 4D72A 4D6FA 1JOVA 3OB8A 2E24A 1HMWA 1HN0A 3VD7A 4E1YA 1NSRA 3IAPA 4D6GA 1Z45A 3MV11 1HN1A 1JZ3A 3BGAA 3VDBA 1NS7A 1RW9A 3I3DA 1HM2A 1RWGA 1CB8A 4F10A 1RWFA 3MV01 3DYPA 1JZ7A 3NFVA 2XHNA 2WVYA 1X1IA 2JKEA 3K25A 3WVFA 1JYWA 4MMIA 2WVXA 1LOHA 1MMZA 1NSSA 5E1QA 1MMYA 1EGUA 2HTAA 1RWAA 4NEIA 1TXKA 2WW3A 1C82A 3MUY1 3MUZ1 1JYVA 3NJVA 1NSXA 1LXMA 2CIQA 1MMXA 3DCDA 3DYMA 3OBAA 1JZ6A 3I3BA 1LF6A 2CISA 4MMHA 1OJPA 1NSZA 2JKAA 2WMGA 3A24A 1QAZA 2WMKA 2WMFA 3NJXA 4D6EA 1I8QA 1UG9A 3DECA 3NREA 3WFAA 3VSNA 3I3EA 1DP0A 3SEPA 2WZSA 2WMHA 1ULVA 3E1F1 2CIRA 2WVXB 3OS7A 4BZEA 1JYNA 1F1SA 2BRWA 3DYOA 1F4HA 4TTGA 1SO0A 1NKGA 1NSVA 2Q1FA 4OK4A 4OZWA 2ZXQA 4DUWA 1OJOA 1NS4A 4J5TA 1LXKA 4D6JA 4D6HA 2D73A 4D6CA 2WDAA 1YQ2A 4FNVA 1K1YA 5A1AA 3CZJA 3T2OA 1RWHA 3T0DA 1HM3A 3VD3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AFL A;  1N7P A;  1HV6 A;  1N7R A;  5JMD A;  2WW0 A;  3T0A A;  3VDC A;  3J7H A;  1N7O A;  1NS0 A;  1JZ2 A;  2WMI A;  1K1W A;  2XSG A;  1K1X A;  1PX4 A;  3VD4 A;  1F4A A;  1LF9 A;  1N7N A;  3NNB A;  2ZQ0 A;  2E22 A;  3T0B A;  1NS2 A;  2WVZ A;  3VD9 A;  1X1H A;  2WCO A;  4D6D A;  1JZ8 A;  1J0N A;  3E7J A;  1L7J A;  1L7K A;  4DUV A;  4BZF A;  4F13 A;  1OJM A;  1N7Q A;  2BRV X;  3IMH A;  4D71 A;  2WW2 A;  3T2P A;  2FUQ A;  1YGA A;  1JZ5 A;  4OK2 A;  5JMF A;  2JKP A;  1X1J A;  1JYX A;  4BZH A;  2WW1 A;  3T2Q A;  3VD5 A;  1MMU A;  1HMU A;  3T08 A;  4BZG A;  3E80 A;  4AQ0 A;  1OJN A;  3ECQ A;  1SNZ A;  2WMI B;  1JZ4 A;  1NS8 A;  1LUR A;  2HTB A;  3VSM A;  3VDA A;  2X03 A;  4D6I A;  2WMJ A;  4DUX A;  3MWX A;  1NSU A;  3A0O A;  4OJZ A;  3T09 A;  4RNL A;  1NSM A;  4OZV A;  1W3Y A;  1PX3 A;  3IAQ A;  2BRP A;  1MN0 A;  1RWC A;  3Q1N A;  1F9G A;  2FUT A;  1J0M A;  4D72 A;  4D6F A;  1JOV A;  3OB8 A;  2E24 A;  1HMW A;  1HN0 A;  3VD7 A;  4E1Y A;  1NSR A;  3IAP A;  4D6G A;  1Z45 A;  3MV1 1;  1HN1 A;  1JZ3 A;  3BGA A;  3VDB A;  1NS7 A;  1RW9 A;  3I3D A;  1HM2 A;  1RWG A;  1CB8 A;  4F10 A;  1RWF A;  3MV0 1;  3DYP A;  1JZ7 A;  3NFV A;  2XHN A;  2WVY A;  1X1I A;  2JKE A;  3K25 A;  1JYW A;  4MMI A;  2WVX A;  1LOH A;  1MMZ A;  1NSS A;  5E1Q A;  1MMY A;  1EGU A;  2HTA A;  1RWA A;  4NEI A;  1TXK A;  2WW3 A;  1C82 A;  3MUY 1;  3MUZ 1;  1JYV A;  3NJV A;  1NSX A;  1LXM A;  2CIQ A;  1MMX A;  3DCD A;  3DYM A;  3OBA A;  1JZ6 A;  3I3B A;  1LF6 A;  2CIS A;  4MMH A;  1OJP A;  1NSZ A;  2JKA A;  2WMG A;  3A24 A;  1QAZ A;  2WMK A;  2WMF A;  3NJX A;  4D6E A;  1I8Q A;  1UG9 A;  3DEC A;  3NRE A;  3WFA A;  3VSN A;  3I3E A;  1DP0 A;  3SEP A;  2WZS A;  2WMH A;  1ULV A;  3E1F 1;  2CIR A;  2WVX B;  3OS7 A;  4BZE A;  1JYN A;  1F1S A;  2BRW A;  3DYO A;  1F4H A;  4TTG A;  1SO0 A;  1NKG A;  1NSV A;  2Q1F A;  4OK4 A;  4OZW A;  2ZXQ A;  4DUW A;  1OJO A;  1NS4 A;  1LXK A;  4D6J A;  4D6H A;  2D73 A;  4D6C A;  2WDA A;  1YQ2 A;  4FNV A;  1K1Y A;  5A1A A;  3CZJ A;  3T2O A;  1RWH A;  3T0D A;  1HM3 A;  3VD3 A; 
#chains in the Genus database with same CATH topology
 4LNB B;  3HXF B;  5JMD A;  3VDC A;  3J7H A;  1HXG A;  1NS0 A;  5EAU A;  2RGK A;  2E2T A;  3OED A;  2F1B A;  3DST B;  1LF9 A;  3T09 A;  2YFN A;  5IK9 A;  2F7O A;  5JPN B;  3CZS A;  3WIQ A;  4ZRQ A;  3P5R A;  2WOH A;  1FCE A;  2R2L B;  1TQU A;  3LOY A;  1X1H A;  2WGQ A;  4DLQ A;  1J0N A;  1HZF A;  4AYR A;  4F13 A;  1OJM A;  1JS4 A;  2BRV X;  4MBG B;  3W5N A;  3MPH A;  1FO3 A;  2GOX A;  3DPY B;  4FUS A;  3SFX B;  2CFK A;  5IKA A;  1L1Y A;  1MMU A;  1HMU A;  3BS6 A;  5CZL A;  1TU5 A;  3NBB A;  2H6I B;  2EAC A;  1OJN A;  3ECQ A;  2XN1 A;  4ZH5 A;  1SNZ A;  4D1I A;  2CWU A;  3Q7F B;  3RJ3 A;  1RJO A;  1KS8 A;  1NS8 A;  1QAK A;  1US1 A;  4D6I A;  2V8I A;  1IVW A;  3A0O A;  1TN6 B;  2B4F A;  3QT3 A;  2BBC A;  5JPM B;  3KBT C;  1MZC B;  1TF4 A;  2DRS A;  1NSM A;  3BUI A;  3EJR A;  4GTT B;  2C10 A;  1F9G A;  2PMV A;  2WY7 A;  1W5Z A;  2H6F B;  3SFY B;  1NSR A;  2BB6 A;  3HXD B;  2F18 A;  1NI1 B;  3AMO A;  1RW9 A;  3D3I A;  3HXC B;  2AHF A;  3SDT A;  1CB8 A;  1RWF A;  3QXF A;  2CQS A;  2FV0 A;  3CV5 A;  1X1I A;  2JG0 A;  3E6U A;  3DSW B;  4QT9 A;  3Q7A B;  4CJ1 A;  3M7E A;  4TF4 A;  3RX8 A;  4KTP A;  4DLO A;  1N95 B;  2ZL8 A;  5DGR A;  2NVP A;  2WW3 A;  1O1T B;  1JYV A;  3NJV A;  1N21 A;  4KKI A;  3M78 A;  1O6R A;  2G0D A;  1LXM A;  2WOF A;  2CIQ A;  4ZRP A;  1FT2 B;  2F6D A;  1JZ6 A;  2EAD A;  4Z4J A;  3DDF A;  3HIG A;  3AMO B;  1PS3 A;  2JKA A;  5DHK A;  1HXC A;  3QFY A;  2WMG A;  3M00 A;  1G9J A;  2FV1 A;  4D6E A;  2A73 B;  4FNT A;  1I8Q A;  3DEC A;  3DX0 A;  3WFA A;  1HXK A;  1KKT A;  3I3E A;  3GT5 A;  2XFG A;  4GTR B;  3W7W A;  2KXS A;  4XUV A;  3BVT A;  2DRQ A;  5IL3 A;  3DYO A;  1SO0 A;  1S64 B;  2ZBL A;  4GTP B;  4DI5 A;  4OK4 A;  4EHM B;  4Q88 A;  2ZXQ A;  1N1B A;  2CG1 A;  3SQC A;  1AYX A;  4J5T A;  4YCR A;  1QAL A;  5FOB B;  1G9G A;  3KSQ B;  1JCR B;  4FJQ A;  1N4S B;  5ILY A;  1K1Y A;  3DX1 A;  3WA3 A;  3PYA A;  2RI8 A;  5EAS A;  5CD2 A;  3CZJ A;  3T0U A;  3KSL B;  4BTW A;  3E32 B;  2BB5 A;  3M7B A;  1HV6 A;  1N7R A;  3D52 A;  2WY8 A;  2XSG A;  3QG0 A;  1K1X A;  3WA2 X;  4WVB A;  3VD4 A;  3TF4 A;  1H3A A;  1QBQ B;  3GZK A;  2ZQ0 A;  2PNC A;  3F59 A;  1QSJ A;  2OQE C;  2OW6 A;  2J5C A;  2WVZ A;  4WU0 A;  5FO9 B;  3ON6 A;  3WIR A;  4K3A A;  1JZ8 A;  2DRR A;  3E7J A;  1H39 A;  4EV5 A;  4BZF A;  4EV2 A;  3X42 A;  3IMH A;  4FNQ A;  5JMF A;  2FBA A;  2WW1 A;  4ZH1 A;  3QR8 A;  1TNO B;  3ANI A;  1H35 A;  3VW5 A;  1W2Z A;  5IKH A;  3E80 A;  1FMI A;  2QNO A;  3QPF A;  4ONT A;  3LVT A;  4MU9 A;  1SA5 B;  2AHG A;  2HTB A;  3VDA A;  5C05 A;  3RRS A;  3BVU A;  4DUX A;  2XN0 A;  1NSU A;  3MWX A;  2OOV C;  4CJ0 A;  3M71 A;  3RX7 A;  4OZV A;  3BVW A;  1PX3 A;  1C3D A;  1JCS B;  3ACT A;  3EU8 A;  5FO7 B;  2YX9 A;  2RI9 A;  2FUT A;  1KZO B;  3M76 A;  3OB8 A;  1SIH A;  4K35 A;  3X3X A;  1NC5 A;  1FAE A;  1W6C A;  4E1Y A;  4AYP A;  5KBP A;  1N9A B;  3SDU A;  3IAP A;  2EAE A;  1Z45 A;  1SQC A;  3S4D A;  5M7I A;  2D8L A;  3S4A A;  3BGA A;  2H6H B;  1JZ7 A;  3SXX A;  3DYP A;  3X3Y A;  3N9H A;  3NFV A;  4L9P B;  2CFL A;  2D5J A;  1AVL A;  2JKE A;  3VXD A;  3M73 A;  1F9O A;  2WVY A;  2XHN A;  3WKG A;  1LTX B;  3WKF A;  3WKI A;  4MMI A;  3BUQ A;  3D4Y A;  1NSS A;  3DSV B;  5E1Q A;  1G87 A;  5CA3 A;  1EGU A;  1O79 A;  2HTA A;  1QQF A;  3OXU A;  3W7X A;  1O7D D;  3E37 B;  2PN5 A;  2F7P A;  3QT9 A;  1MMX A;  2OQE A;  3BUD A;  1O1R B;  1D8D B;  3REN A;  2V3P A;  3SDQ A;  4UFC A;  1TNZ B;  1N4P B;  1HX9 A;  1FT1 B;  3H3K A;  4D4A A;  1O5M B;  2WO0 A;  3M75 A;  2WMK A;  3WIW A;  3M01 A;  3QSP A;  4BOK A;  1UG9 A;  1R33 A;  3NRE A;  3W7S A;  2YIK A;  1V5C A;  2WZS A;  3U7V A;  1ULV A;  1NL4 B;  1JYN A;  1F1S A;  2JF4 A;  4LNV A;  1TQS A;  3Q73 B;  4BTX A;  1F4H A;  2F7Q A;  2Q1F A;  2A8Z A;  3W7U A;  4OZW A;  2RDY A;  3SX1 A;  1AGM A;  1TNU B;  2H6G B;  3QXQ A;  2OOV A;  1IA6 A;  5IK0 A;  1NS4 A;  1TQW A;  4RNQ A;  1UI7 A;  3D51 A;  4Z4L A;  5GW7 A;  4L6X A;  5A1A A;  1GLM A;  1N4R B;  3DSS B;  1IVU A;  3T0D A;  1HM3 A;  1V7X A;  2E2U A;  3VD3 A;  3AFL A;  3S9V A;  1TNY B;  1DYU A;  2WW0 A;  3T0A A;  1N7O A;  1JZ2 A;  4WVC A;  3E30 B;  1D8E B;  1K1W A;  1PX4 A;  1SII A;  4GAX A;  4DOE A;  3HII A;  3BLC A;  1N7N A;  3NNB A;  3QDE A;  3E33 B;  2E22 A;  2WYN A;  2ONH A;  3T0B A;  3WC3 A;  1H36 A;  3LZ9 A;  3E34 B;  2WCO A;  2CFG A;  1TQV A;  3BVV A;  5ILZ A;  1L7K A;  4DUV A;  2AFA A;  3EQA A;  3D50 A;  1DOG A;  3PZ4 B;  1N7Q A;  5ILI A;  4V1S A;  1YGA A;  1SPU A;  4OK2 A;  4FXK B;  2JKP A;  1JYX A;  1UMP A;  2NOJ A;  4V1R A;  1W6G A;  3BUP A;  3EJT A;  3T2Q A;  1OAC A;  4BZH A;  3T08 A;  1GHQ A;  1TN7 B;  3BLB A;  4GTQ B;  5KKB A;  3DRA B;  1GAI A;  2V3N A;  2KXR A;  5ILK A;  2CG0 A;  4AQ0 A;  3N0F A;  2ALW A;  1D6Z A;  3EJS A;  2I07 B;  1TN8 B;  4FNU A;  4ZG8 A;  3ACS A;  1LUR A;  3VSM A;  2X03 A;  2WII B;  1SA4 B;  2WMJ A;  4OJZ A;  2E2V A;  3SAE A;  2Y74 A;  3EJP A;  2BRP A;  1MN0 A;  3IAQ A;  1RWC A;  3Q1N A;  1HXA A;  2XWJ B;  1JOV A;  5AGD A;  2E24 A;  1W6K A;  3G6J B;  1HN0 A;  3VD7 A;  3EJU A;  3SDR A;  1GXM A;  4FNS A;  2XWB B;  5MEH A;  1WMO A;  3P5P A;  4D6G A;  3G4D A;  1HN1 A;  1G6I A;  2Z07 A;  2ZIS B;  3M02 A;  3D4Z A;  3BUB A;  1RWG A;  5GY3 A;  1O6H A;  1PU4 A;  1FBW A;  1K72 A;  1H14 A;  3WVF A;  1FP3 A;  1KWF A;  3NBJ A;  2GH4 A;  2ZIR B;  2DRO A;  3EUV B;  4KFE A;  1X9D A;  1H37 A;  1HWW A;  1MMZ A;  1GAH A;  1MMY A;  3KII A;  3MUY 1;  1RWA A;  3C72 B;  1C82 A;  1VD5 A;  1CLC A;  3EU5 B;  5IK6 A;  3PQI A;  4YDE B;  1UI8 A;  3DSX B;  5DHI A;  1NSX A;  2V8J A;  4D94 A;  3DX3 A;  3DCD A;  3DYM A;  1H3B A;  3D5S A;  2VN4 A;  2JJB A;  3DDG A;  3S4B A;  1JRQ A;  2SQC A;  1IQY A;  4BOJ A;  4MMH A;  2EAB A;  4LNG B;  3A24 A;  1GA2 A;  5DGQ A;  3M72 A;  4L0G A;  1DCE B;  3VSN A;  4DOD A;  3RSY A;  4D4C A;  1LVN A;  5M7Y A;  1TQT A;  2ZZR A;  3D5R A;  3H2W A;  4GL3 A;  3RX5 A;  4AYQ A;  2WMH A;  2CIR A;  3E1F 1;  4C1S A;  4BZE A;  2BRW A;  1V5D A;  4AYO A;  1WU4 A;  4TTG A;  1H13 A;  1NKG A;  2BT3 A;  4LIX A;  3ANK A;  1W7C A;  1N94 B;  3GLY A;  1QX1 A;  3CIH A;  1LXK A;  4D6J A;  4D6H A;  3K7X A;  3CZN A;  2D73 A;  1H54 A;  4BTY A;  4D6C A;  4WVA A;  3QFZ A;  1YQ2 A;  3PZ3 B;  2WYH A;  3T2O A;  4D4B A;  3WUX A;  4GTS B;  1KRF A;  1WMN A;  2CFW A;  1FO2 A;  4GTM B;  1N7P A;  1WZZ A;  1FBO A;  2WIN B;  5ILH A;  3PZ1 B;  4KFD A;  2WMI A;  2GZ6 A;  4YDO B;  1V7V A;  4GTO B;  5E2J A;  3T33 A;  3E73 A;  1F4A A;  2OW7 A;  2Y73 A;  1IQX A;  3ANJ A;  3HXE B;  3UD1 A;  1QAF A;  3HXB B;  1JCQ B;  1N1Z A;  3WKH A;  1NS2 A;  1UT9 A;  3QRY A;  2CWV A;  2P0V A;  3AFJ A;  1S63 B;  4CE7 A;  4EL8 A;  3KBU C;  3VD9 A;  4KKJ A;  4D6D A;  1L7J A;  1KZP B;  1DL2 A;  3K11 A;  3Q78 B;  3M7C A;  1QWN A;  3PMM A;  1XWT A;  3A3V A;  1HCU A;  2F0Y B;  4D71 A;  2WW2 A;  2FUQ A;  3T2P A;  1JZ5 A;  1D6U A;  3P2C A;  1X1J A;  1N9E A;  3X40 A;  2YFO A;  2C11 A;  3VD5 A;  1IVV A;  4BZG A;  1LD7 B;  1W6J A;  3KQ4 A;  4D8O A;  1WMP A;  5IL8 A;  5ILJ A;  2XN2 A;  2OKX A;  2W0Q A;  2WMI B;  4KTR A;  4KFF A;  1JZ4 A;  5FO8 B;  3KLS A;  3W7T A;  1N23 A;  2IEJ B;  1A2V A;  1N22 A;  3X3Z A;  1KRE A;  4GTV B;  3MI6 A;  1GXN A;  1X81 B;  1FPP B;  3H7L A;  1KSI A;  1W3Y A;  2XQW A;  4RNL A;  3W5M A;  3PYB A;  3TY1 A;  3S4C A;  1J0M A;  1N4Q B;  4D6F A;  2CQT A;  1KSD A;  3DSU B;  1HMW A;  1V7W A;  4D72 A;  2D1W A;  1N24 A;  4FNR A;  3MV1 1;  1JZ3 A;  3VDB A;  1NXC A;  3M74 A;  1XWQ A;  2V8K A;  1HM2 A;  1NS7 A;  2ONG A;  3I3D A;  4F10 A;  3MV0 1;  3SDV A;  2FYV A;  3K25 A;  2VN7 A;  3HI7 A;  1H3C A;  3KN4 A;  2B39 A;  1JYW A;  2WVX A;  1LOH A;  3BVX A;  1TNB B;  1D6Y A;  3Q79 B;  1AVK A;  4D1J A;  2CFD A;  1O1S B;  4NEI A;  1TXK A;  2CWT A;  1N20 A;  3EJQ A;  3MUZ 1;  1IVX A;  3CU7 A;  3PZ2 B;  2F1A A;  1AV4 A;  1F9D A;  1RQ5 A;  1IS9 A;  3OBA A;  3N0G A;  3QWT A;  3I3B A;  1LF6 A;  1IU7 A;  3X41 A;  1O6Q A;  1KFG A;  1QWU A;  1IA7 A;  2CIS A;  3M7L A;  5GZK A;  1OJP A;  1KSC A;  1NSZ A;  3ALA A;  1WU6 A;  4D4D A;  1QAZ A;  2F7R A;  3UD2 A;  5ILD A;  2WMF A;  2BED B;  1GXO A;  1L2A A;  3NJX A;  1XW2 A;  3K5T A;  1W4N A;  4TXT A;  1R76 A;  1DP0 A;  3SEP A;  3OS7 A;  1WU5 A;  2WVX B;  4M76 A;  1CEM A;  2WYI A;  3X17 A;  4FNP A;  2FUZ A;  3DX4 A;  3Q75 B;  1NSV A;  1LD8 B;  1H12 A;  4DUW A;  2G02 A;  3M77 A;  3G4F A;  4JJJ A;  4Q2B A;  1OJO A;  1R34 A;  3PGB A;  1HTY A;  1GSZ A;  2WDA A;  1RKY A;  4FNV A;  5EAT A;  1EKM A;  5IM1 A;  1RWH A;  3EZ8 A;  4FXG B;  3DX2 A; 
#chains in the Genus database with same CATH homology
 3AFL A;  1N7P A;  1HV6 A;  1N7R A;  5JMD A;  2WW0 A;  3T0A A;  3VDC A;  3J7H A;  1N7O A;  1NS0 A;  1JZ2 A;  2WMI A;  1K1W A;  2XSG A;  1K1X A;  1PX4 A;  3VD4 A;  1F4A A;  1LF9 A;  3BLC A;  1N7N A;  3NNB A;  2ZQ0 A;  2E22 A;  3T0B A;  1NS2 A;  2WVZ A;  3VD9 A;  1X1H A;  2WCO A;  4D6D A;  1JZ8 A;  1J0N A;  3E7J A;  1L7J A;  1L7K A;  4DUV A;  4BZF A;  4F13 A;  1OJM A;  1N7Q A;  2BRV X;  3IMH A;  4D71 A;  2WW2 A;  3T2P A;  2FUQ A;  1YGA A;  1JZ5 A;  4OK2 A;  5JMF A;  2JKP A;  1X1J A;  1JYX A;  4BZH A;  2WW1 A;  3T2Q A;  3VD5 A;  1MMU A;  1HMU A;  3T08 A;  3BS6 A;  4BZG A;  3E80 A;  4AQ0 A;  1OJN A;  3ECQ A;  1SNZ A;  2WMI B;  1JZ4 A;  1NS8 A;  1LUR A;  2HTB A;  3VSM A;  3VDA A;  2X03 A;  4D6I A;  2WMJ A;  4DUX A;  3MWX A;  1NSU A;  3A0O A;  4OJZ A;  3T09 A;  4RNL A;  1NSM A;  4OZV A;  1W3Y A;  1PX3 A;  3IAQ A;  2BRP A;  1MN0 A;  3TY1 A;  1RWC A;  3Q1N A;  1F9G A;  2FUT A;  1J0M A;  4D72 A;  4D6F A;  1JOV A;  3OB8 A;  2E24 A;  1HMW A;  1HN0 A;  3VD7 A;  4E1Y A;  1NSR A;  3IAP A;  4D6G A;  1Z45 A;  3MV1 1;  1HN1 A;  1JZ3 A;  3BGA A;  3VDB A;  1NS7 A;  1RW9 A;  3I3D A;  1HM2 A;  1RWG A;  1CB8 A;  4F10 A;  1RWF A;  3MV0 1;  3DYP A;  1JZ7 A;  3NFV A;  2XHN A;  2WVY A;  1X1I A;  2JKE A;  3K25 A;  3WVF A;  1JYW A;  4MMI A;  2WVX A;  1LOH A;  1MMZ A;  1NSS A;  5E1Q A;  1MMY A;  1EGU A;  2HTA A;  1RWA A;  4NEI A;  1TXK A;  2WW3 A;  1C82 A;  3MUY 1;  3MUZ 1;  1JYV A;  3NJV A;  1NSX A;  1LXM A;  2CIQ A;  1MMX A;  3DCD A;  3DYM A;  3OBA A;  1JZ6 A;  3I3B A;  1LF6 A;  2CIS A;  4MMH A;  1OJP A;  1NSZ A;  2JKA A;  2WMG A;  3A24 A;  1QAZ A;  2WMK A;  2WMF A;  3NJX A;  4D6E A;  1I8Q A;  1UG9 A;  3DEC A;  3NRE A;  3WFA A;  3VSN A;  3I3E A;  1DP0 A;  3SEP A;  2WZS A;  2WMH A;  1ULV A;  3E1F 1;  2CIR A;  2WVX B;  3OS7 A;  4BZE A;  1JYN A;  1F1S A;  2BRW A;  3DYO A;  1F4H A;  4TTG A;  1SO0 A;  1NKG A;  1NSV A;  2Q1F A;  4OK4 A;  4OZW A;  2ZXQ A;  4DUW A;  1OJO A;  1NS4 A;  4J5T A;  1LXK A;  4D6J A;  4D6H A;  2D73 A;  4D6C A;  2WDA A;  1YQ2 A;  4FNV A;  1K1Y A;  5A1A A;  3CZJ A;  3T2O A;  1RWH A;  3T0D A;  1HM3 A;  3VD3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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