4R28A

Mspji restriction endonuclease in complex with 27-mer oligonucleotide
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
449
structure length
449
Chain Sequence
IAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Mycobacterium sp. jls
molecule keywords Restriction endonuclease
total genus 90
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04471 Mrr_cat Restriction endonuclease
A PF18062 RE_AspBHI_N Restriction endonuclease AspBHI N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.20 Mainly Beta Roll PUA domain-like PUA domain-like 4r28A01
3.40.91.100 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 4r28A02
4RZLA 4F0QA 4OC8A 4R28A 4F0PA
chains in the Genus database with same CATH superfamily
3DW9A 3WVGA 1BAMA 3CLZA 5D42A 3CAEA 5CGVA 4E5JA 4PW7A 3BAMA 4AWHA 3WVHA 5CL0A 3WVIA 3MQ6A 4AWFA 4RZLA 3BI7A 5JHTA 1CFRA 4PW6A 2FQZA 3Q0DA 3OLNA 2FOKA 3F8IA 4AWMA 3F8JB 4AWGA 4PW5A 2ZKGA 5D9JA 2P14A 3HW4A 4NJ5A 5D8UA 5I13A 2ZKFA 2XI5A 4ZQQA 3ODHA 3HW3A 1M0DA 5DEBA 4CGXA 3Q0CA 1BHMA 4AWKA 4ZHZA 4YGIA 3DPGA 3V20A 4F0QA 1VRRA 3WVKA 2P0JA 4NFZA 1M0IA 2ZO0B 2ZKDA 2GB7A 3BM3A 4AVGA 3V1ZA 3WVPA 4CGSA 4E5EA 2E52A 4ZI0A 3EBJA 3N78A 3V21A 4F0PA 2ZKEA 1DFMA 2PB7A 5FDDA 4AVQA 3Q0FA 1SDOA 3Q0BX 2XI7A 3HW5A 2ZO1B 5D2OA 5DESA 2ZO2B 3HW6A 5CCYA 5EGAA 4E5GA 4YYLA 1D2IA 5CZNA 4E5HA 4CHCA 1KNVA 4AVLA 1ES8A 3DVOA 1FOKA 3FDEA 1DC1A 5D4GA 4E5FA 2EWFA 5FDGA 1FZRA 5JHVA 4R28A 3N7BA 3DWHA 4E5IA 3A4KA 1ESGA 4OC8A 4E5LA 2BAMA 2PFJA 3MQYA 5DBSA
chains in the Genus database with same CATH topology
3DW9A 3WVGA 1BAMA 5D42A 3CAEA 5CGVA 4E5JA 3BAMA 4AWHA 3WVHA 5CL0A 3WVIA 3MQ6A 4AWFA 4RZLA 5JHTA 1CFRA 2FQZA 3Q0DA 2FOKA 4AWMA 4AWGA 5D9JA 2P14A 3HW4A 5D8UA 5I13A 2XI5A 3ODHA 4ZQQA 3HW3A 1M0DA 5DEBA 4CGXA 3Q0CA 1BHMA 4AWKA 4ZHZA 4YGIA 3DPGA 3V20A 4F0QA 1VRRA 3WVKA 2P0JA 4NFZA 1M0IA 2GB7A 3BM3A 4AVGA 3V1ZA 3WVPA 4CGSA 4E5EA 2E52A 4ZI0A 3EBJA 3N78A 3V21A 4F0PA 1DFMA 5FDDA 4AVQA 3Q0FA 1SDOA 3Q0BX 2XI7A 3HW5A 5D2OA 5DESA 3HW6A 5CCYA 5EGAA 4E5GA 4YYLA 1D2IA 5CZNA 4E5HA 4CHCA 1KNVA 4AVLA 1ES8A 3DVOA 1FOKA 1DC1A 5D4GA 4E5FA 2EWFA 5FDGA 1FZRA 5JHVA 4R28A 3N7BA 4E5IA 3A4KA 1ESGA 4OC8A 4E5LA 2BAMA 2PFJA 3MQYA 5DBSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RZL A;  4F0Q A;  4OC8 A;  4R28 A;  4F0P A; 
#chains in the Genus database with same CATH topology
 3DW9 A;  3WVG A;  1BAM A;  3CLZ A;  5D42 A;  3CAE A;  5CGV A;  4E5J A;  4PW7 A;  3BAM A;  4AWH A;  3WVH A;  5CL0 A;  3WVI A;  3MQ6 A;  4AWF A;  4RZL A;  3BI7 A;  5JHT A;  1CFR A;  4PW6 A;  2FQZ A;  3Q0D A;  3OLN A;  2FOK A;  3F8I A;  4AWM A;  3F8J B;  4AWG A;  4PW5 A;  2ZKG A;  5D9J A;  2P14 A;  3HW4 A;  4NJ5 A;  5D8U A;  5I13 A;  2ZKF A;  2XI5 A;  4ZQQ A;  3ODH A;  3HW3 A;  1M0D A;  5DEB A;  4CGX A;  3Q0C A;  1BHM A;  4AWK A;  4ZHZ A;  4YGI A;  3DPG A;  3V20 A;  4F0Q A;  1VRR A;  3WVK A;  2P0J A;  4NFZ A;  1M0I A;  2ZO0 B;  2ZKD A;  2GB7 A;  3BM3 A;  4AVG A;  3V1Z A;  3WVP A;  4CGS A;  4E5E A;  2E52 A;  4ZI0 A;  3EBJ A;  3N78 A;  3V21 A;  4F0P A;  2ZKE A;  1DFM A;  2PB7 A;  5FDD A;  4AVQ A;  3Q0F A;  1SDO A;  3Q0B X;  2XI7 A;  3HW5 A;  2ZO1 B;  5D2O A;  5DES A;  2ZO2 B;  3HW6 A;  5CCY A;  5EGA A;  4E5G A;  4YYL A;  1D2I A;  5CZN A;  4E5H A;  4CHC A;  1KNV A;  4AVL A;  1ES8 A;  3DVO A;  1FOK A;  3FDE A;  1DC1 A;  5D4G A;  4E5F A;  2EWF A;  5FDG A;  1FZR A;  5JHV A;  4R28 A;  3N7B A;  3DWH A;  4E5I A;  3A4K A;  1ESG A;  4OC8 A;  4E5L A;  2BAM A;  2PFJ A;  3MQY A;  5DBS A; 
#chains in the Genus database with same CATH homology
 3DW9 A;  3WVG A;  1BAM A;  5D42 A;  3CAE A;  5CGV A;  4E5J A;  3BAM A;  4AWH A;  3WVH A;  5CL0 A;  3WVI A;  3MQ6 A;  4AWF A;  4RZL A;  5JHT A;  1CFR A;  2FQZ A;  3Q0D A;  2FOK A;  4AWM A;  4AWG A;  5D9J A;  2P14 A;  3HW4 A;  5D8U A;  5I13 A;  2XI5 A;  3ODH A;  4ZQQ A;  3HW3 A;  1M0D A;  5DEB A;  4CGX A;  3Q0C A;  1BHM A;  4AWK A;  4ZHZ A;  4YGI A;  3DPG A;  3V20 A;  4F0Q A;  1VRR A;  3WVK A;  2P0J A;  4NFZ A;  1M0I A;  2GB7 A;  3BM3 A;  4AVG A;  3V1Z A;  3WVP A;  4CGS A;  4E5E A;  2E52 A;  4ZI0 A;  3EBJ A;  3N78 A;  3V21 A;  4F0P A;  1DFM A;  5FDD A;  4AVQ A;  3Q0F A;  1SDO A;  3Q0B X;  2XI7 A;  3HW5 A;  5D2O A;  5DES A;  3HW6 A;  5CCY A;  5EGA A;  4E5G A;  4YYL A;  1D2I A;  5CZN A;  4E5H A;  4CHC A;  1KNV A;  4AVL A;  1ES8 A;  3DVO A;  1FOK A;  1DC1 A;  5D4G A;  4E5F A;  2EWF A;  5FDG A;  1FZR A;  5JHV A;  4R28 A;  3N7B A;  4E5I A;  3A4K A;  1ESG A;  4OC8 A;  4E5L A;  2BAM A;  2PFJ A;  3MQY A;  5DBS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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