4R28A

Mspji restriction endonuclease in complex with 27-mer oligonucleotide
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
449
structure length
449
Chain Sequence
IAWAASAEVANKPRLVFVGDELRYAQGANQRDVELDGFVNYHWLTSPGGLGLPKVMLEAGINAPAEVVGPDRSRRALIAIRSSPWKAGHETNPWHDEFDLDHGHVRYFGDHKPSTVGLPGETKGNRLLLEAARLHAGTTREERLLAPPLFLFRAVTVHRAGRAVVKGHVEFCGAAIIERLEHVVQRDPETGRSFPNLSLDLAVVSGGEIDGVDFRWIDDRRNAALAAGETLRHAPESWIRWVRQGRLAIPGIRRRVLASAVQSSKEQQPASGSAEAATLQTLYKFYDGRKHAFELLASRVAAEVFRESGARYKEGWLSRSSGDGGVDFIGRIDMGSLKASTPVVVLGQAKCIQPTSSVSPEQVARVVARLRRGWIGVYVTTGSFSRQAQVEIIDDQYPVVLIAGGTLAATVRRMVQANYGGDLDALLASTVDEYGAAVTHRRPEEVISL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Mycobacterium sp. jls
molecule keywords Restriction endonuclease
total genus 90
structure length 449
sequence length 449
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-08-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04471 Mrr_cat Restriction endonuclease
A PF18062 RE_AspBHI_N Restriction endonuclease AspBHI N-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.280.20 Mainly Beta Roll PUA domain-like PUA domain-like 4r28A01
3.40.91.100 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 4r28A02
4OC8A 4F0QA 4RZLA 4F0PA 4R28A
chains in the Genus database with same CATH superfamily
3MQYA 3V1ZA 3Q0DA 2FQZA 4PW7A 5FDGA 1ES8A 3V21A 4AWHA 1CFRA 2ZKDA 4ZQQA 5CGVA 3V20A 3Q0BX 1FZRA 3F8JB 4AWGA 2ZO2B 2BAMA 3Q0FA 1DFMA 2P0JA 5FDDA 3HW6A 2PB7A 3WVIA 5JHVA 1BAMA 3BM3A 3WVGA 5DESA 2PFJA 2ZKGA 3HW5A 1BHMA 2ZKEA 2P14A 3F8IA 4E5EA 4AWFA 4PW6A 1KNVA 3BI7A 4AWMA 4YYLA 4AVLA 4F0QA 5JHTA 5CL0A 3Q0CA 1VRRA 4E5GA 4CHCA 1ESGA 2XI7A 3DWHA 1M0IA 4PW5A 3N7BA 2E52A 4AVGA 4NFZA 2EWFA 2FOKA 5D42A 4E5JA 3WVKA 3CAEA 3EBJA 3BAMA 4OC8A 5DBSA 3HW4A 5I13A 5DEBA 2ZO0B 3A4KA 1FOKA 4YGIA 3DVOA 5CCYA 3HW3A 5D9JA 4AVQA 4ZI0A 3ODHA 5EGAA 3MQ6A 2XI5A 2ZO1B 4ZHZA 4E5IA 4R28A 3WVHA 3CLZA 1M0DA 4CGXA 3N78A 4NJ5A 5D8UA 4E5LA 5D2OA 5D4GA 1DC1A 4RZLA 4F0PA 3FDEA 2ZKFA 3OLNA 4E5HA 2GB7A 5CZNA 1SDOA 3DW9A 4CGSA 3DPGA 3WVPA 1D2IA 4AWKA 4E5FA
chains in the Genus database with same CATH topology
3MQYA 3V1ZA 3Q0DA 2FQZA 5FDGA 1ES8A 3V21A 4AWHA 1CFRA 4ZQQA 5CGVA 3V20A 1FZRA 3Q0BX 4AWGA 2BAMA 3Q0FA 1DFMA 2P0JA 5FDDA 3HW6A 3WVIA 5JHVA 1BAMA 3BM3A 3WVGA 5DESA 2PFJA 3HW5A 1BHMA 2P14A 4E5EA 4AWFA 1KNVA 4AWMA 4YYLA 4AVLA 4F0QA 5JHTA 5CL0A 3Q0CA 1VRRA 4E5GA 4CHCA 1ESGA 2XI7A 1M0IA 3N7BA 2E52A 4AVGA 4NFZA 2EWFA 2FOKA 5D42A 4E5JA 3WVKA 3CAEA 3EBJA 3BAMA 4OC8A 5DBSA 3HW4A 5I13A 5DEBA 3A4KA 1FOKA 4YGIA 3DVOA 5CCYA 3HW3A 5D9JA 4AVQA 4ZI0A 3ODHA 5EGAA 3MQ6A 2XI5A 4ZHZA 4E5IA 3WVHA 4R28A 1M0DA 4CGXA 3N78A 5D8UA 4E5LA 5D2OA 5D4GA 1DC1A 4RZLA 4F0PA 4E5HA 2GB7A 5CZNA 1SDOA 3DW9A 4CGSA 3DPGA 3WVPA 1D2IA 4AWKA 4E5FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OC8 A;  4F0Q A;  4RZL A;  4F0P A;  4R28 A; 
#chains in the Genus database with same CATH topology
 3MQY A;  3V1Z A;  3Q0D A;  2FQZ A;  4PW7 A;  5FDG A;  1ES8 A;  3V21 A;  4AWH A;  1CFR A;  2ZKD A;  4ZQQ A;  5CGV A;  3V20 A;  3Q0B X;  1FZR A;  3F8J B;  4AWG A;  2ZO2 B;  2BAM A;  3Q0F A;  1DFM A;  2P0J A;  5FDD A;  3HW6 A;  2PB7 A;  3WVI A;  5JHV A;  1BAM A;  3BM3 A;  3WVG A;  5DES A;  2PFJ A;  2ZKG A;  3HW5 A;  1BHM A;  2ZKE A;  2P14 A;  3F8I A;  4E5E A;  4AWF A;  4PW6 A;  1KNV A;  3BI7 A;  4AWM A;  4YYL A;  4AVL A;  4F0Q A;  5JHT A;  5CL0 A;  3Q0C A;  1VRR A;  4E5G A;  4CHC A;  1ESG A;  2XI7 A;  3DWH A;  1M0I A;  4PW5 A;  3N7B A;  2E52 A;  4AVG A;  4NFZ A;  2EWF A;  2FOK A;  5D42 A;  4E5J A;  3WVK A;  3CAE A;  3EBJ A;  3BAM A;  4OC8 A;  5DBS A;  3HW4 A;  5I13 A;  5DEB A;  2ZO0 B;  3A4K A;  1FOK A;  4YGI A;  3DVO A;  5CCY A;  3HW3 A;  5D9J A;  4AVQ A;  4ZI0 A;  3ODH A;  5EGA A;  3MQ6 A;  2XI5 A;  2ZO1 B;  4ZHZ A;  4E5I A;  4R28 A;  3WVH A;  3CLZ A;  1M0D A;  4CGX A;  3N78 A;  4NJ5 A;  5D8U A;  4E5L A;  5D2O A;  5D4G A;  1DC1 A;  4RZL A;  4F0P A;  3FDE A;  2ZKF A;  3OLN A;  4E5H A;  2GB7 A;  5CZN A;  1SDO A;  3DW9 A;  4CGS A;  3DPG A;  3WVP A;  1D2I A;  4AWK A;  4E5F A; 
#chains in the Genus database with same CATH homology
 3MQY A;  3V1Z A;  3Q0D A;  2FQZ A;  5FDG A;  1ES8 A;  3V21 A;  4AWH A;  1CFR A;  4ZQQ A;  5CGV A;  3V20 A;  1FZR A;  3Q0B X;  4AWG A;  2BAM A;  3Q0F A;  1DFM A;  2P0J A;  5FDD A;  3HW6 A;  3WVI A;  5JHV A;  1BAM A;  3BM3 A;  3WVG A;  5DES A;  2PFJ A;  3HW5 A;  1BHM A;  2P14 A;  4E5E A;  4AWF A;  1KNV A;  4AWM A;  4YYL A;  4AVL A;  4F0Q A;  5JHT A;  5CL0 A;  3Q0C A;  1VRR A;  4E5G A;  4CHC A;  1ESG A;  2XI7 A;  1M0I A;  3N7B A;  2E52 A;  4AVG A;  4NFZ A;  2EWF A;  2FOK A;  5D42 A;  4E5J A;  3WVK A;  3CAE A;  3EBJ A;  3BAM A;  4OC8 A;  5DBS A;  3HW4 A;  5I13 A;  5DEB A;  3A4K A;  1FOK A;  4YGI A;  3DVO A;  5CCY A;  3HW3 A;  5D9J A;  4AVQ A;  4ZI0 A;  3ODH A;  5EGA A;  3MQ6 A;  2XI5 A;  4ZHZ A;  4E5I A;  3WVH A;  4R28 A;  1M0D A;  4CGX A;  3N78 A;  5D8U A;  4E5L A;  5D2O A;  5D4G A;  1DC1 A;  4RZL A;  4F0P A;  4E5H A;  2GB7 A;  5CZN A;  1SDO A;  3DW9 A;  4CGS A;  3DPG A;  3WVP A;  1D2I A;  4AWK A;  4E5F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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