5A8CA

The ultra high resolution structure of a novel alpha-l-arabinofuranosidase (ctgh43) from clostridium thermocellum atcc 27405 with bound trimethyl n-oxide (trs)
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
299
structure length
299
Chain Sequence
ADYPIFSQRFTADPAAVVYNGRLYIYCSHDSDATPGQSTYNIPDITCISTDDLKNWTDHGEVFNAKRDSRWASVSWAPSIVYRNNKFYLYYGNGGNGIGVAVSDSPTGPFKDPLPGPLVSWNTPGVQPAQNMWLFDPGVFVDDDGQAYMYFGGNGQNNIRVIKLGNDMISTVGSAMTMSAPRFFEAAYMHKYNGKYYFSYASDFSQGASKIEYMMSDKPTTGFQYKGVILPQPPDNYSNNNHHAIVEYKGNWYVVYHNRTVAKQRGLDPVYQRNVCIDQMFYNADGTIKQVVPTVDGLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular determinants of substrate specificity revealed by the structure of Clostridium thermocellum arabinofuranosidase 43A from glycosyl hydrolase family 43 subfamily 16.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium thermocellum
molecule keywords CARBOHYDRATE BINDING FAMILY 6
total genus 81
structure length 299
sequence length 299
ec nomenclature ec 3.2.1.55: Non-reducing end alpha-L-arabinofuranosidase.
pdb deposition date 2015-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04616 Glyco_hydro_43 Glycosyl hydrolases family 43
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.115.10.20 Mainly Beta 5 Propeller Tachylectin-2; Chain A Glycosyl hydrolase domain; family 43 5a8cA00
3VT0A 3CU9A 5JOZA 4D47A 3WPVA 3PIJA 3QEFA 2X8TA 1Y7BA 3C7OA 1PT2A 3OM7A 4PVAA 5JOYA 4O8NA 3BYJA 4KC8A 1UV4A 5GLLA 3LFIA 3R4YA 3VT1A 3LDRA 1Y9GA 5GLNA 4KCAA 2YFRA 4ONZA 3C7HA 1GYHA 1OYGA 3WMYA 5A8CA 4COTA 3LIGA 3KF3A 3KF5A 3LF7A 3BYKA 5FMDA 4FFHA 3VT2A 1Y4WA 3UGGA 3WPUA 1W18A 3AKHA 4FFFA 5ANNA 5FMBA 1YRZA 3WPZA 5FK8A 2EXIA 3C2UA 2XQRA 3D60A 2EXJA 3LV4A 5FK7A 3WASA 5JOWA 3U75A 3ZXKA 5GLMA 3WMZA 3C7EA 4N2RA 4UDKE 3R67A 3NQHA 1YI7A 3PIGA 3WN0A 3U14A 3QEDA 3KSTA 4MLGA 3WATA 3D61A 1UYPA 2AC1A 5FKBA 5GLKA 2B4WA 5B6TA 5AYDA 3LEMA 4N2ZA 1VKDA 4UDJA 2QQWA 2X8SA 5FLWA 3D5ZA 4PVIA 3QEEA 3ZXJA 2X8FA 2YFSA 4KC7A 3R4ZA 4AK6A 4KCBA 2YFTA 1WL7A 3C7GA 3TAWA 3VSFA 3QC2A 5GLRA 5A7VA 4O8OA 1ST8A 3BYNA 3OM5A 4UDKA 2EXHA 1GYDB 5AYEA 3VSRA 3OM2A 2QQUA 4NOVA 1YIFA 2EXKA 3OM4A 5FKCA 5AYCA 4FFGA 4U6BA 5A8DA 3ZXLA 4N4BA 3QZ4A 5FMCA 4UDIA 1Y9MA 3LIHA 5A7VB 3WAUA 5B6SA 3VSZA 3OM6A 3AKFA 3WN1A 4QQSA 3BYLA 3RWKX 3D5YA 3AKGA 3WN2A 3WPYA 3UGHA 3VSSA 5GLPA 4EQVA 5JOXA 3AKIA 4FFIA 3SC7X 4AK7A 4KMIA 4N1IA 2OXBA 3C7FA 2ADDA 3P2NA 5FIXA 2QQVA 4U6DA 5C0PA 2VDTA 5GLOA 1W2TA 4UDGA 3LDKA 5AY9A 3UGFA 4O8PA 2ADEA 2AEYA 1GYEB 3K1UA 4AK5A 5GLQA 2AEZA
chains in the Genus database with same CATH superfamily
3VT0A 3CU9A 5JOZA 1TL2A 3WPVA 4D47A 3PIJA 3QEFA 2X8TA 1Y7BA 3C7OA 1PT2A 3OM7A 4PVAA 5JOYA 4O8NA 3BYJA 4KC8A 1UV4A 5GLLA 3LFIA 3R4YA 3VT1A 3LDRA 1Y9GA 5GLNA 4KCAA 2YFRA 4ONZA 3C7HA 1GYHA 1OYGA 3WMYA 5A8CA 4COTA 3LIGA 3KF3A 3KF5A 3LF7A 3BYKA 5FMDA 4FFHA 3VT2A 1Y4WA 3UGGA 3WPUA 1W18A 3AKHA 4FFFA 5ANNA 5FMBA 1YRZA 3WPZA 5FK8A 2EXIA 3C2UA 2XQRA 3D60A 2EXJA 3LV4A 5FK7A 3WASA 5JOWA 3U75A 3ZXKA 5GLMA 3WMZA 3C7EA 4N2RA 4UDKE 3R67A 3NQHA 1YI7A 3PIGA 3WN0A 3U14A 3QEDA 3KSTA 4MLGA 3WATA 3D61A 1UYPA 2AC1A 5FKBA 5GLKA 2B4WA 5B6TA 5AYDA 3LEMA 4N2ZA 1VKDA 4UDJA 2QQWA 2X8SA 5FLWA 3D5ZA 4PVIA 3QEEA 3ZXJA 2X8FA 2YFSA 4KC7A 3R4ZA 4AK6A 4KCBA 2YFTA 1WL7A 3C7GA 3TAWA 3VSFA 3QC2A 5GLRA 5A7VA 4O8OA 1ST8A 3BYNA 3OM5A 4UDKA 2EXHA 1GYDB 5AYEA 3VSRA 3OM2A 2QQUA 4NOVA 1YIFA 2EXKA 3OM4A 5FKCA 5AYCA 4FFGA 4U6BA 5A8DA 3ZXLA 4N4BA 3QZ4A 5FMCA 4UDIA 1Y9MA 3LIHA 5A7VB 3WAUA 5B6SA 3VSZA 3OM6A 3AKFA 3WN1A 4QQSA 3BYLA 3RWKX 3D5YA 3AKGA 3WN2A 3WPYA 3UGHA 3VSSA 5GLPA 4EQVA 5JOXA 3AKIA 4FFIA 3SC7X 4AK7A 4KMIA 4N1IA 2OXBA 3C7FA 2ADDA 3P2NA 5FIXA 2QQVA 4U6DA 5C0PA 2VDTA 5GLOA 1W2TA 4UDGA 3LDKA 5AY9A 3UGFA 4O8PA 2ADEA 2AEYA 1GYEB 3K1UA 4AK5A 5GLQA 5C2MA 2AEZA
chains in the Genus database with same CATH topology
3VT0A 3CU9A 5JOZA 4D47A 3WPVA 3PIJA 3QEFA 2X8TA 1Y7BA 3C7OA 1PT2A 3OM7A 4PVAA 5JOYA 4O8NA 3BYJA 4KC8A 1UV4A 5GLLA 3LFIA 3R4YA 3VT1A 3LDRA 1Y9GA 5GLNA 4KCAA 2YFRA 4ONZA 3C7HA 1GYHA 1OYGA 3WMYA 5A8CA 4COTA 3LIGA 3KF3A 3KF5A 3LF7A 3BYKA 5FMDA 4FFHA 3VT2A 1Y4WA 3UGGA 3WPUA 1W18A 3AKHA 4FFFA 5ANNA 5FMBA 1YRZA 3WPZA 5FK8A 2EXIA 3C2UA 2XQRA 3D60A 2EXJA 3LV4A 5FK7A 3WASA 5JOWA 3U75A 3ZXKA 5GLMA 3WMZA 3C7EA 4N2RA 4UDKE 3R67A 3NQHA 1YI7A 3PIGA 3WN0A 3U14A 3QEDA 3KSTA 4MLGA 3WATA 3D61A 1UYPA 2AC1A 5FKBA 5GLKA 2B4WA 5B6TA 5AYDA 3LEMA 4N2ZA 1VKDA 4UDJA 2QQWA 2X8SA 5FLWA 3D5ZA 4PVIA 3QEEA 3ZXJA 2X8FA 2YFSA 4KC7A 3R4ZA 4AK6A 4KCBA 2YFTA 1WL7A 3C7GA 3TAWA 3VSFA 3QC2A 5GLRA 5A7VA 4O8OA 1ST8A 3BYNA 3OM5A 4UDKA 2EXHA 1GYDB 5AYEA 3VSRA 3OM2A 2QQUA 4NOVA 1YIFA 2EXKA 3OM4A 5FKCA 5AYCA 4FFGA 4U6BA 5A8DA 3ZXLA 4N4BA 3QZ4A 5FMCA 4UDIA 1Y9MA 3LIHA 5A7VB 3WAUA 5B6SA 3VSZA 3OM6A 3AKFA 3WN1A 4QQSA 3BYLA 3RWKX 3D5YA 3AKGA 3WN2A 3WPYA 3UGHA 3VSSA 5GLPA 4EQVA 5JOXA 3AKIA 4FFIA 3SC7X 4AK7A 4KMIA 4N1IA 2OXBA 3C7FA 2ADDA 3P2NA 5FIXA 2QQVA 4U6DA 5C0PA 2VDTA 5GLOA 1W2TA 4UDGA 3LDKA 5AY9A 3UGFA 4O8PA 2ADEA 2AEYA 1GYEB 3K1UA 4AK5A 5GLQA 2AEZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VT0 A;  3CU9 A;  5JOZ A;  4D47 A;  3WPV A;  3PIJ A;  3QEF A;  2X8T A;  1Y7B A;  3C7O A;  1PT2 A;  3OM7 A;  4PVA A;  5JOY A;  4O8N A;  3BYJ A;  4KC8 A;  1UV4 A;  5GLL A;  3LFI A;  3R4Y A;  3VT1 A;  3LDR A;  1Y9G A;  5GLN A;  4KCA A;  2YFR A;  4ONZ A;  3C7H A;  1GYH A;  1OYG A;  3WMY A;  5A8C A;  4COT A;  3LIG A;  3KF3 A;  3KF5 A;  3LF7 A;  3BYK A;  5FMD A;  4FFH A;  3VT2 A;  1Y4W A;  3UGG A;  3WPU A;  1W18 A;  3AKH A;  4FFF A;  5ANN A;  5FMB A;  1YRZ A;  3WPZ A;  5FK8 A;  2EXI A;  3C2U A;  2XQR A;  3D60 A;  2EXJ A;  3LV4 A;  5FK7 A;  3WAS A;  5JOW A;  3U75 A;  3ZXK A;  5GLM A;  3WMZ A;  3C7E A;  4N2R A;  4UDK E;  3R67 A;  3NQH A;  1YI7 A;  3PIG A;  3WN0 A;  3U14 A;  3QED A;  3KST A;  4MLG A;  3WAT A;  3D61 A;  1UYP A;  2AC1 A;  5FKB A;  5GLK A;  2B4W A;  5B6T A;  5AYD A;  3LEM A;  4N2Z A;  1VKD A;  4UDJ A;  2QQW A;  2X8S A;  5FLW A;  3D5Z A;  4PVI A;  3QEE A;  3ZXJ A;  2X8F A;  2YFS A;  4KC7 A;  3R4Z A;  4AK6 A;  4KCB A;  2YFT A;  1WL7 A;  3C7G A;  3TAW A;  3VSF A;  3QC2 A;  5GLR A;  5A7V A;  4O8O A;  1ST8 A;  3BYN A;  3OM5 A;  4UDK A;  2EXH A;  1GYD B;  5AYE A;  3VSR A;  3OM2 A;  2QQU A;  4NOV A;  1YIF A;  2EXK A;  3OM4 A;  5FKC A;  5AYC A;  4FFG A;  4U6B A;  5A8D A;  3ZXL A;  4N4B A;  3QZ4 A;  5FMC A;  4UDI A;  1Y9M A;  3LIH A;  5A7V B;  3WAU A;  5B6S A;  3VSZ A;  3OM6 A;  3AKF A;  3WN1 A;  4QQS A;  3BYL A;  3RWK X;  3D5Y A;  3AKG A;  3WN2 A;  3WPY A;  3UGH A;  3VSS A;  5GLP A;  4EQV A;  5JOX A;  3AKI A;  4FFI A;  3SC7 X;  4AK7 A;  4KMI A;  4N1I A;  2OXB A;  3C7F A;  2ADD A;  3P2N A;  5FIX A;  2QQV A;  4U6D A;  5C0P A;  2VDT A;  5GLO A;  1W2T A;  4UDG A;  3LDK A;  5AY9 A;  3UGF A;  4O8P A;  2ADE A;  2AEY A;  1GYE B;  3K1U A;  4AK5 A;  5GLQ A;  2AEZ A; 
#chains in the Genus database with same CATH topology
 3VT0 A;  3CU9 A;  5JOZ A;  1TL2 A;  3WPV A;  4D47 A;  3PIJ A;  3QEF A;  2X8T A;  1Y7B A;  3C7O A;  1PT2 A;  3OM7 A;  4PVA A;  5JOY A;  4O8N A;  3BYJ A;  4KC8 A;  1UV4 A;  5GLL A;  3LFI A;  3R4Y A;  3VT1 A;  3LDR A;  1Y9G A;  5GLN A;  4KCA A;  2YFR A;  4ONZ A;  3C7H A;  1GYH A;  1OYG A;  3WMY A;  5A8C A;  4COT A;  3LIG A;  3KF3 A;  3KF5 A;  3LF7 A;  3BYK A;  5FMD A;  4FFH A;  3VT2 A;  1Y4W A;  3UGG A;  3WPU A;  1W18 A;  3AKH A;  4FFF A;  5ANN A;  5FMB A;  1YRZ A;  3WPZ A;  5FK8 A;  2EXI A;  3C2U A;  2XQR A;  3D60 A;  2EXJ A;  3LV4 A;  5FK7 A;  3WAS A;  5JOW A;  3U75 A;  3ZXK A;  5GLM A;  3WMZ A;  3C7E A;  4N2R A;  4UDK E;  3R67 A;  3NQH A;  1YI7 A;  3PIG A;  3WN0 A;  3U14 A;  3QED A;  3KST A;  4MLG A;  3WAT A;  3D61 A;  1UYP A;  2AC1 A;  5FKB A;  5GLK A;  2B4W A;  5B6T A;  5AYD A;  3LEM A;  4N2Z A;  1VKD A;  4UDJ A;  2QQW A;  2X8S A;  5FLW A;  3D5Z A;  4PVI A;  3QEE A;  3ZXJ A;  2X8F A;  2YFS A;  4KC7 A;  3R4Z A;  4AK6 A;  4KCB A;  2YFT A;  1WL7 A;  3C7G A;  3TAW A;  3VSF A;  3QC2 A;  5GLR A;  5A7V A;  4O8O A;  1ST8 A;  3BYN A;  3OM5 A;  4UDK A;  2EXH A;  1GYD B;  5AYE A;  3VSR A;  3OM2 A;  2QQU A;  4NOV A;  1YIF A;  2EXK A;  3OM4 A;  5FKC A;  5AYC A;  4FFG A;  4U6B A;  5A8D A;  3ZXL A;  4N4B A;  3QZ4 A;  5FMC A;  4UDI A;  1Y9M A;  3LIH A;  5A7V B;  3WAU A;  5B6S A;  3VSZ A;  3OM6 A;  3AKF A;  3WN1 A;  4QQS A;  3BYL A;  3RWK X;  3D5Y A;  3AKG A;  3WN2 A;  3WPY A;  3UGH A;  3VSS A;  5GLP A;  4EQV A;  5JOX A;  3AKI A;  4FFI A;  3SC7 X;  4AK7 A;  4KMI A;  4N1I A;  2OXB A;  3C7F A;  2ADD A;  3P2N A;  5FIX A;  2QQV A;  4U6D A;  5C0P A;  2VDT A;  5GLO A;  1W2T A;  4UDG A;  3LDK A;  5AY9 A;  3UGF A;  4O8P A;  2ADE A;  2AEY A;  1GYE B;  3K1U A;  4AK5 A;  5GLQ A;  5C2M A;  2AEZ A; 
#chains in the Genus database with same CATH homology
 3VT0 A;  3CU9 A;  5JOZ A;  4D47 A;  3WPV A;  3PIJ A;  3QEF A;  2X8T A;  1Y7B A;  3C7O A;  1PT2 A;  3OM7 A;  4PVA A;  5JOY A;  4O8N A;  3BYJ A;  4KC8 A;  1UV4 A;  5GLL A;  3LFI A;  3R4Y A;  3VT1 A;  3LDR A;  1Y9G A;  5GLN A;  4KCA A;  2YFR A;  4ONZ A;  3C7H A;  1GYH A;  1OYG A;  3WMY A;  5A8C A;  4COT A;  3LIG A;  3KF3 A;  3KF5 A;  3LF7 A;  3BYK A;  5FMD A;  4FFH A;  3VT2 A;  1Y4W A;  3UGG A;  3WPU A;  1W18 A;  3AKH A;  4FFF A;  5ANN A;  5FMB A;  1YRZ A;  3WPZ A;  5FK8 A;  2EXI A;  3C2U A;  2XQR A;  3D60 A;  2EXJ A;  3LV4 A;  5FK7 A;  3WAS A;  5JOW A;  3U75 A;  3ZXK A;  5GLM A;  3WMZ A;  3C7E A;  4N2R A;  4UDK E;  3R67 A;  3NQH A;  1YI7 A;  3PIG A;  3WN0 A;  3U14 A;  3QED A;  3KST A;  4MLG A;  3WAT A;  3D61 A;  1UYP A;  2AC1 A;  5FKB A;  5GLK A;  2B4W A;  5B6T A;  5AYD A;  3LEM A;  4N2Z A;  1VKD A;  4UDJ A;  2QQW A;  2X8S A;  5FLW A;  3D5Z A;  4PVI A;  3QEE A;  3ZXJ A;  2X8F A;  2YFS A;  4KC7 A;  3R4Z A;  4AK6 A;  4KCB A;  2YFT A;  1WL7 A;  3C7G A;  3TAW A;  3VSF A;  3QC2 A;  5GLR A;  5A7V A;  4O8O A;  1ST8 A;  3BYN A;  3OM5 A;  4UDK A;  2EXH A;  1GYD B;  5AYE A;  3VSR A;  3OM2 A;  2QQU A;  4NOV A;  1YIF A;  2EXK A;  3OM4 A;  5FKC A;  5AYC A;  4FFG A;  4U6B A;  5A8D A;  3ZXL A;  4N4B A;  3QZ4 A;  5FMC A;  4UDI A;  1Y9M A;  3LIH A;  5A7V B;  3WAU A;  5B6S A;  3VSZ A;  3OM6 A;  3AKF A;  3WN1 A;  4QQS A;  3BYL A;  3RWK X;  3D5Y A;  3AKG A;  3WN2 A;  3WPY A;  3UGH A;  3VSS A;  5GLP A;  4EQV A;  5JOX A;  3AKI A;  4FFI A;  3SC7 X;  4AK7 A;  4KMI A;  4N1I A;  2OXB A;  3C7F A;  2ADD A;  3P2N A;  5FIX A;  2QQV A;  4U6D A;  5C0P A;  2VDT A;  5GLO A;  1W2T A;  4UDG A;  3LDK A;  5AY9 A;  3UGF A;  4O8P A;  2ADE A;  2AEY A;  1GYE B;  3K1U A;  4AK5 A;  5GLQ A;  2AEZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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