5A8CA

The ultra high resolution structure of a novel alpha-l-arabinofuranosidase (ctgh43) from clostridium thermocellum atcc 27405 with bound trimethyl n-oxide (trs)
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
299
structure length
299
Chain Sequence
ADYPIFSQRFTADPAAVVYNGRLYIYCSHDSDATPGQSTYNIPDITCISTDDLKNWTDHGEVFNAKRDSRWASVSWAPSIVYRNNKFYLYYGNGGNGIGVAVSDSPTGPFKDPLPGPLVSWNTPGVQPAQNMWLFDPGVFVDDDGQAYMYFGGNGQNNIRVIKLGNDMISTVGSAMTMSAPRFFEAAYMHKYNGKYYFSYASDFSQGASKIEYMMSDKPTTGFQYKGVILPQPPDNYSNNNHHAIVEYKGNWYVVYHNRTVAKQRGLDPVYQRNVCIDQMFYNADGTIKQVVPTVDGLK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Molecular determinants of substrate specificity revealed by the structure of Clostridium thermocellum arabinofuranosidase 43A from glycosyl hydrolase family 43 subfamily 16.
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium thermocellum
molecule keywords CARBOHYDRATE BINDING FAMILY 6
total genus 81
structure length 299
sequence length 299
ec nomenclature ec 3.2.1.55: Non-reducing end alpha-L-arabinofuranosidase.
pdb deposition date 2015-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04616 Glyco_hydro_43 Glycosyl hydrolases family 43
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.115.10.20 Mainly Beta 5 Propeller Tachylectin-2; Chain A Glycosyl hydrolase domain; family 43 5a8cA00
5GLNA 1VKDA 2ADDA 3QZ4A 3WMYA 2OXBA 3VT2A 2QQWA 4KCBA 3VSRA 2X8FA 4NOVA 3C2UA 5AYEA 3LIGA 4UDIA 3C7EA 3AKGA 3KSTA 3WN0A 1GYEB 3OM5A 3WASA 3TAWA 3K1UA 3OM2A 4ONZA 3WPYA 1PT2A 2AC1A 3LDKA 3NQHA 3ZXLA 3C7GA 3BYLA 5B6SA 3OM6A 4MLGA 5AYCA 3P2NA 1W18A 3PIGA 3U75A 4KC7A 3UGGA 1Y9GA 3ZXKA 4D47A 3LIHA 3C7HA 2B4WA 1OYGA 3KF3A 4AK6A 4U6DA 3AKHA 4FFIA 4N1IA 5AYDA 1GYHA 3QEDA 4UDKA 5C0PA 1UYPA 1Y9MA 2QQUA 5GLKA 4UDKE 3VSFA 5FKCA 2X8TA 2EXKA 5A7VA 3D61A 1ST8A 3RWKX 5JOWA 4COTA 1YIFA 2QQVA 3OM7A 4QQSA 2YFSA 2AEZA 2VDTA 3CU9A 5JOYA 5GLQA 3WATA 3BYKA 2EXIA 2XQRA 3VSSA 2EXJA 5AY9A 2YFRA 2YFTA 3QC2A 5GLLA 4N2ZA 2EXHA 3WAUA 3VT0A 3BYJA 3QEEA 4O8OA 3WPUA 1YI7A 5FMBA 1W2TA 5ANNA 4AK5A 4UDJA 3VT1A 3LF7A 5GLMA 3D5ZA 5FMCA 3LEMA 4KC8A 3VSZA 5A8CA 3SC7X 3AKIA 3U14A 2X8SA 4UDGA 5GLPA 5A7VB 3WPZA 3R4YA 4FFFA 3WN1A 2ADEA 3KF5A 5FIXA 4N4BA 3AKFA 1GYDB 4FFHA 5B6TA 4FFGA 1WL7A 5FMDA 5FLWA 3BYNA 5A8DA 3C7OA 4EQVA 3PIJA 3UGFA 3WN2A 4O8PA 4PVIA 5FK8A 3LV4A 3UGHA 3R67A 4KMIA 5GLOA 5FK7A 3LFIA 4PVAA 3ZXJA 4AK7A 3R4ZA 5JOZA 5JOXA 4O8NA 3D60A 3LDRA 3QEFA 1Y7BA 4N2RA 5GLRA 3WMZA 3WPVA 3D5YA 3OM4A 1UV4A 1YRZA 2AEYA 4KCAA 4U6BA 3C7FA 5FKBA 1Y4WA
chains in the Genus database with same CATH superfamily
5GLNA 1VKDA 5C2MA 2ADDA 3QZ4A 3WMYA 2OXBA 3VT2A 2QQWA 4KCBA 3VSRA 2X8FA 4NOVA 3C2UA 5AYEA 3LIGA 4UDIA 3C7EA 3AKGA 3KSTA 3WN0A 1GYEB 3OM5A 3WASA 3TAWA 3K1UA 3OM2A 4ONZA 3WPYA 1PT2A 2AC1A 3LDKA 3NQHA 3ZXLA 3C7GA 3BYLA 5B6SA 3OM6A 4MLGA 5AYCA 3P2NA 1W18A 3PIGA 3U75A 4KC7A 3UGGA 1Y9GA 3ZXKA 4D47A 3LIHA 3C7HA 2B4WA 1OYGA 3KF3A 4AK6A 4U6DA 3AKHA 4FFIA 4N1IA 5AYDA 1GYHA 3QEDA 4UDKA 5C0PA 1UYPA 1Y9MA 2QQUA 5GLKA 4UDKE 3VSFA 5FKCA 2X8TA 2EXKA 5A7VA 3D61A 1ST8A 3RWKX 5JOWA 4COTA 1YIFA 2QQVA 3OM7A 4QQSA 2YFSA 2AEZA 2VDTA 3CU9A 5JOYA 5GLQA 3WATA 3BYKA 2EXIA 2XQRA 3VSSA 2EXJA 5AY9A 2YFRA 2YFTA 3QC2A 5GLLA 4N2ZA 2EXHA 3WAUA 3VT0A 3BYJA 3QEEA 4O8OA 3WPUA 1TL2A 1YI7A 5FMBA 1W2TA 5ANNA 4AK5A 4UDJA 3VT1A 3LF7A 5GLMA 3D5ZA 5FMCA 3LEMA 4KC8A 3VSZA 5A8CA 3SC7X 3AKIA 3U14A 2X8SA 4UDGA 5GLPA 5A7VB 3WPZA 3R4YA 4FFFA 3WN1A 2ADEA 3KF5A 5FIXA 4N4BA 3AKFA 1GYDB 4FFHA 5B6TA 4FFGA 1WL7A 5FMDA 5FLWA 3BYNA 5A8DA 3C7OA 4EQVA 3PIJA 3UGFA 3WN2A 4O8PA 4PVIA 5FK8A 3LV4A 3UGHA 3R67A 4KMIA 5GLOA 5FK7A 3LFIA 4PVAA 3ZXJA 4AK7A 3R4ZA 5JOZA 5JOXA 4O8NA 3D60A 3LDRA 3QEFA 1Y7BA 4N2RA 5GLRA 3WMZA 3WPVA 3D5YA 3OM4A 1UV4A 1YRZA 2AEYA 4KCAA 4U6BA 3C7FA 5FKBA 1Y4WA
chains in the Genus database with same CATH topology
5GLNA 1VKDA 2ADDA 3QZ4A 3WMYA 2OXBA 3VT2A 2QQWA 4KCBA 3VSRA 2X8FA 4NOVA 3C2UA 5AYEA 3LIGA 4UDIA 3C7EA 3AKGA 3KSTA 3WN0A 1GYEB 3OM5A 3WASA 3TAWA 3K1UA 3OM2A 4ONZA 3WPYA 1PT2A 2AC1A 3LDKA 3NQHA 3ZXLA 3C7GA 3BYLA 5B6SA 3OM6A 4MLGA 5AYCA 3P2NA 1W18A 3PIGA 3U75A 4KC7A 3UGGA 1Y9GA 3ZXKA 4D47A 3LIHA 3C7HA 2B4WA 1OYGA 3KF3A 4AK6A 4U6DA 3AKHA 4FFIA 4N1IA 5AYDA 1GYHA 3QEDA 4UDKA 5C0PA 1UYPA 1Y9MA 2QQUA 5GLKA 4UDKE 3VSFA 5FKCA 2X8TA 2EXKA 5A7VA 3D61A 1ST8A 3RWKX 5JOWA 4COTA 1YIFA 2QQVA 3OM7A 4QQSA 2YFSA 2AEZA 2VDTA 3CU9A 5JOYA 5GLQA 3WATA 3BYKA 2EXIA 2XQRA 3VSSA 2EXJA 5AY9A 2YFRA 2YFTA 3QC2A 5GLLA 4N2ZA 2EXHA 3WAUA 3VT0A 3BYJA 3QEEA 4O8OA 3WPUA 1YI7A 5FMBA 1W2TA 5ANNA 4AK5A 4UDJA 3VT1A 3LF7A 5GLMA 3D5ZA 5FMCA 3LEMA 4KC8A 3VSZA 5A8CA 3SC7X 3AKIA 3U14A 2X8SA 4UDGA 5GLPA 5A7VB 3WPZA 3R4YA 4FFFA 3WN1A 2ADEA 3KF5A 5FIXA 4N4BA 3AKFA 1GYDB 4FFHA 5B6TA 4FFGA 1WL7A 5FMDA 5FLWA 3BYNA 5A8DA 3C7OA 4EQVA 3PIJA 3UGFA 3WN2A 4O8PA 4PVIA 5FK8A 3LV4A 3UGHA 3R67A 4KMIA 5GLOA 5FK7A 3LFIA 4PVAA 3ZXJA 4AK7A 3R4ZA 5JOZA 5JOXA 4O8NA 3D60A 3LDRA 3QEFA 1Y7BA 4N2RA 5GLRA 3WMZA 3WPVA 3D5YA 3OM4A 1UV4A 1YRZA 2AEYA 4KCAA 4U6BA 3C7FA 5FKBA 1Y4WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GLN A;  1VKD A;  2ADD A;  3QZ4 A;  3WMY A;  2OXB A;  3VT2 A;  2QQW A;  4KCB A;  3VSR A;  2X8F A;  4NOV A;  3C2U A;  5AYE A;  3LIG A;  4UDI A;  3C7E A;  3AKG A;  3KST A;  3WN0 A;  1GYE B;  3OM5 A;  3WAS A;  3TAW A;  3K1U A;  3OM2 A;  4ONZ A;  3WPY A;  1PT2 A;  2AC1 A;  3LDK A;  3NQH A;  3ZXL A;  3C7G A;  3BYL A;  5B6S A;  3OM6 A;  4MLG A;  5AYC A;  3P2N A;  1W18 A;  3PIG A;  3U75 A;  4KC7 A;  3UGG A;  1Y9G A;  3ZXK A;  4D47 A;  3LIH A;  3C7H A;  2B4W A;  1OYG A;  3KF3 A;  4AK6 A;  4U6D A;  3AKH A;  4FFI A;  4N1I A;  5AYD A;  1GYH A;  3QED A;  4UDK A;  5C0P A;  1UYP A;  1Y9M A;  2QQU A;  5GLK A;  4UDK E;  3VSF A;  5FKC A;  2X8T A;  2EXK A;  5A7V A;  3D61 A;  1ST8 A;  3RWK X;  5JOW A;  4COT A;  1YIF A;  2QQV A;  3OM7 A;  4QQS A;  2YFS A;  2AEZ A;  2VDT A;  3CU9 A;  5JOY A;  5GLQ A;  3WAT A;  3BYK A;  2EXI A;  2XQR A;  3VSS A;  2EXJ A;  5AY9 A;  2YFR A;  2YFT A;  3QC2 A;  5GLL A;  4N2Z A;  2EXH A;  3WAU A;  3VT0 A;  3BYJ A;  3QEE A;  4O8O A;  3WPU A;  1YI7 A;  5FMB A;  1W2T A;  5ANN A;  4AK5 A;  4UDJ A;  3VT1 A;  3LF7 A;  5GLM A;  3D5Z A;  5FMC A;  3LEM A;  4KC8 A;  3VSZ A;  5A8C A;  3SC7 X;  3AKI A;  3U14 A;  2X8S A;  4UDG A;  5GLP A;  5A7V B;  3WPZ A;  3R4Y A;  4FFF A;  3WN1 A;  2ADE A;  3KF5 A;  5FIX A;  4N4B A;  3AKF A;  1GYD B;  4FFH A;  5B6T A;  4FFG A;  1WL7 A;  5FMD A;  5FLW A;  3BYN A;  5A8D A;  3C7O A;  4EQV A;  3PIJ A;  3UGF A;  3WN2 A;  4O8P A;  4PVI A;  5FK8 A;  3LV4 A;  3UGH A;  3R67 A;  4KMI A;  5GLO A;  5FK7 A;  3LFI A;  4PVA A;  3ZXJ A;  4AK7 A;  3R4Z A;  5JOZ A;  5JOX A;  4O8N A;  3D60 A;  3LDR A;  3QEF A;  1Y7B A;  4N2R A;  5GLR A;  3WMZ A;  3WPV A;  3D5Y A;  3OM4 A;  1UV4 A;  1YRZ A;  2AEY A;  4KCA A;  4U6B A;  3C7F A;  5FKB A;  1Y4W A; 
#chains in the Genus database with same CATH topology
 5GLN A;  1VKD A;  5C2M A;  2ADD A;  3QZ4 A;  3WMY A;  2OXB A;  3VT2 A;  2QQW A;  4KCB A;  3VSR A;  2X8F A;  4NOV A;  3C2U A;  5AYE A;  3LIG A;  4UDI A;  3C7E A;  3AKG A;  3KST A;  3WN0 A;  1GYE B;  3OM5 A;  3WAS A;  3TAW A;  3K1U A;  3OM2 A;  4ONZ A;  3WPY A;  1PT2 A;  2AC1 A;  3LDK A;  3NQH A;  3ZXL A;  3C7G A;  3BYL A;  5B6S A;  3OM6 A;  4MLG A;  5AYC A;  3P2N A;  1W18 A;  3PIG A;  3U75 A;  4KC7 A;  3UGG A;  1Y9G A;  3ZXK A;  4D47 A;  3LIH A;  3C7H A;  2B4W A;  1OYG A;  3KF3 A;  4AK6 A;  4U6D A;  3AKH A;  4FFI A;  4N1I A;  5AYD A;  1GYH A;  3QED A;  4UDK A;  5C0P A;  1UYP A;  1Y9M A;  2QQU A;  5GLK A;  4UDK E;  3VSF A;  5FKC A;  2X8T A;  2EXK A;  5A7V A;  3D61 A;  1ST8 A;  3RWK X;  5JOW A;  4COT A;  1YIF A;  2QQV A;  3OM7 A;  4QQS A;  2YFS A;  2AEZ A;  2VDT A;  3CU9 A;  5JOY A;  5GLQ A;  3WAT A;  3BYK A;  2EXI A;  2XQR A;  3VSS A;  2EXJ A;  5AY9 A;  2YFR A;  2YFT A;  3QC2 A;  5GLL A;  4N2Z A;  2EXH A;  3WAU A;  3VT0 A;  3BYJ A;  3QEE A;  4O8O A;  3WPU A;  1TL2 A;  1YI7 A;  5FMB A;  1W2T A;  5ANN A;  4AK5 A;  4UDJ A;  3VT1 A;  3LF7 A;  5GLM A;  3D5Z A;  5FMC A;  3LEM A;  4KC8 A;  3VSZ A;  5A8C A;  3SC7 X;  3AKI A;  3U14 A;  2X8S A;  4UDG A;  5GLP A;  5A7V B;  3WPZ A;  3R4Y A;  4FFF A;  3WN1 A;  2ADE A;  3KF5 A;  5FIX A;  4N4B A;  3AKF A;  1GYD B;  4FFH A;  5B6T A;  4FFG A;  1WL7 A;  5FMD A;  5FLW A;  3BYN A;  5A8D A;  3C7O A;  4EQV A;  3PIJ A;  3UGF A;  3WN2 A;  4O8P A;  4PVI A;  5FK8 A;  3LV4 A;  3UGH A;  3R67 A;  4KMI A;  5GLO A;  5FK7 A;  3LFI A;  4PVA A;  3ZXJ A;  4AK7 A;  3R4Z A;  5JOZ A;  5JOX A;  4O8N A;  3D60 A;  3LDR A;  3QEF A;  1Y7B A;  4N2R A;  5GLR A;  3WMZ A;  3WPV A;  3D5Y A;  3OM4 A;  1UV4 A;  1YRZ A;  2AEY A;  4KCA A;  4U6B A;  3C7F A;  5FKB A;  1Y4W A; 
#chains in the Genus database with same CATH homology
 5GLN A;  1VKD A;  2ADD A;  3QZ4 A;  3WMY A;  2OXB A;  3VT2 A;  2QQW A;  4KCB A;  3VSR A;  2X8F A;  4NOV A;  3C2U A;  5AYE A;  3LIG A;  4UDI A;  3C7E A;  3AKG A;  3KST A;  3WN0 A;  1GYE B;  3OM5 A;  3WAS A;  3TAW A;  3K1U A;  3OM2 A;  4ONZ A;  3WPY A;  1PT2 A;  2AC1 A;  3LDK A;  3NQH A;  3ZXL A;  3C7G A;  3BYL A;  5B6S A;  3OM6 A;  4MLG A;  5AYC A;  3P2N A;  1W18 A;  3PIG A;  3U75 A;  4KC7 A;  3UGG A;  1Y9G A;  3ZXK A;  4D47 A;  3LIH A;  3C7H A;  2B4W A;  1OYG A;  3KF3 A;  4AK6 A;  4U6D A;  3AKH A;  4FFI A;  4N1I A;  5AYD A;  1GYH A;  3QED A;  4UDK A;  5C0P A;  1UYP A;  1Y9M A;  2QQU A;  5GLK A;  4UDK E;  3VSF A;  5FKC A;  2X8T A;  2EXK A;  5A7V A;  3D61 A;  1ST8 A;  3RWK X;  5JOW A;  4COT A;  1YIF A;  2QQV A;  3OM7 A;  4QQS A;  2YFS A;  2AEZ A;  2VDT A;  3CU9 A;  5JOY A;  5GLQ A;  3WAT A;  3BYK A;  2EXI A;  2XQR A;  3VSS A;  2EXJ A;  5AY9 A;  2YFR A;  2YFT A;  3QC2 A;  5GLL A;  4N2Z A;  2EXH A;  3WAU A;  3VT0 A;  3BYJ A;  3QEE A;  4O8O A;  3WPU A;  1YI7 A;  5FMB A;  1W2T A;  5ANN A;  4AK5 A;  4UDJ A;  3VT1 A;  3LF7 A;  5GLM A;  3D5Z A;  5FMC A;  3LEM A;  4KC8 A;  3VSZ A;  5A8C A;  3SC7 X;  3AKI A;  3U14 A;  2X8S A;  4UDG A;  5GLP A;  5A7V B;  3WPZ A;  3R4Y A;  4FFF A;  3WN1 A;  2ADE A;  3KF5 A;  5FIX A;  4N4B A;  3AKF A;  1GYD B;  4FFH A;  5B6T A;  4FFG A;  1WL7 A;  5FMD A;  5FLW A;  3BYN A;  5A8D A;  3C7O A;  4EQV A;  3PIJ A;  3UGF A;  3WN2 A;  4O8P A;  4PVI A;  5FK8 A;  3LV4 A;  3UGH A;  3R67 A;  4KMI A;  5GLO A;  5FK7 A;  3LFI A;  4PVA A;  3ZXJ A;  4AK7 A;  3R4Z A;  5JOZ A;  5JOX A;  4O8N A;  3D60 A;  3LDR A;  3QEF A;  1Y7B A;  4N2R A;  5GLR A;  3WMZ A;  3WPV A;  3D5Y A;  3OM4 A;  1UV4 A;  1YRZ A;  2AEY A;  4KCA A;  4U6B A;  3C7F A;  5FKB A;  1Y4W A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...