1GXBA

Anthranilate phosphoribosyltransferase in complex with pyrophosphate and magnesium
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
343
structure length
339
Chain Sequence
MNINEILKKLINKSDLEINEAEELAKAIIRGEVPEILVSAILVALRMKGESKNEIVGFARAMRELAIKIDVPNAIDTAGGLGTVNVSTASAILLSLVNPVAKHGNRAVSGKSGSADVLEALGYNIIVPPERAKELVNKTNFVFLFAQYYHPAMKNVANVRKTLGIRTIFNILGPLTNPANAKYQLMGVFSKDHLDLLSKSAYELDFNKIILVYGEPGIDEVSPIGNTFMKIVSKRGIEEVKLNVTDFGISPIPIEKLIVNSAEDSAIKIVRAFLGKDEHVAEFIKINTAVALFALDRVGDFREGYEYADHLIEKSLDKLNEIISMNGDVTKLKTIVVKS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Analysis of Two Enzymes Catalysing Reverse Metabolic Reactions Implies Common Ancestry
pubmed doi rcsb
molecule tags Transferase
molecule keywords ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE
total genus 129
structure length 339
sequence length 343
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.18: Anthranilate phosphoribosyltransferase.
pdb deposition date 2002-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 1gxbA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 1gxbA02
4N8QA 1UOUA 4ZOFA 4OWOA 4N5VA 3R88A 4YI7A 4GKMA 4GTNA 1ZXYA 2DSJA 4YYYA 4YEKA 4X5EA 4X58A 4XR5A 5BNEA 5BO2A 4M0RA 3QR9A 2WK5A 3H5QA 4MUOA 4X46A 2J0FA 1BRWA 1KGZA 4X5AA 4X5BA 5C1RA 4ZOJA 4GA5A 4OWNA 5EP8A 3QS8A 4EAFA 2GVQA 1ZVWA 3UU1A 5BYTA 1AZYA 1V8GA 2TPTA 4EADA 4X5CA 4GA6A 4GA4A 4GIUA 4ZTVA 2BPQA 1VQUA 4OWVA 4OWMA 1ZYKA 4X59A 3TWPA 1O17A 4X5DA 4IJ1A 3GBRA 3QSAA 3QQSA 2ELCA 5EY3A 2WK6A 4OWSA 3R6CA 4OWUA 1OTPA 5C2LA 5BO3A 4LHMA 4ZOKA 1KHDA 1GXBA 5C7SA 4OWQA 4HKMA 4N93A
chains in the Genus database with same CATH superfamily
4N8QA 1UOUA 4ZOFA 4F3FC 4OWOA 4N5VA 3R88A 4YI7A 4GKMA 4GTNA 1ZXYA 2DSJA 4YYYA 4YEKA 4X5EA 4X58A 4XR5A 5BNEA 5BO2A 4M0RA 3QR9A 2WK5A 3H5QA 4MUOA 4X46A 2J0FA 1BRWA 1KGZA 1RRZA 4X5AA 4X5BA 5C1RA 4ZOJA 4GA5A 4OWNA 5EP8A 3QS8A 4EAFA 2GVQA 1ZVWA 3UU1A 5BYTA 1AZYA 1V8GA 2TPTA 4EADA 4X5CA 4GA6A 4GA4A 4GIUA 4ZTVA 2BPQA 1VQUA 4OWVA 1RF8B 4OWMA 1ZYKA 4X59A 3TWPA 1O17A 4X5DA 4IJ1A 3GBRA 3QSAA 3QQSA 2ELCA 5EY3A 2WK6A 4OWSA 3R6CA 4OWUA 1OTPA 5C2LA 5BO3A 4LHMA 4ZOKA 1KHDA 1GXBA 5C7SA 4OWQA 4HKMA 4N93A
chains in the Genus database with same CATH topology
4N8QA 1UOUA 4ZOFA 4OWOA 4N5VA 3R88A 4YI7A 4GKMA 4GTNA 1ZXYA 2DSJA 4YYYA 4YEKA 4X5EA 4X58A 4XR5A 5BNEA 5BO2A 4M0RA 3QR9A 2WK5A 3H5QA 4MUOA 4X46A 2J0FA 1BRWA 1KGZA 4X5AA 4X5BA 5C1RA 4ZOJA 4GA5A 4OWNA 5EP8A 3QS8A 4EAFA 2GVQA 1ZVWA 3UU1A 5BYTA 1AZYA 1V8GA 2TPTA 4EADA 4X5CA 4GA6A 4GA4A 4GIUA 4ZTVA 2BPQA 1VQUA 4OWVA 4OWMA 1ZYKA 4X59A 3TWPA 1O17A 4X5DA 4IJ1A 3GBRA 3QSAA 3QQSA 2ELCA 5EY3A 2WK6A 4OWSA 3R6CA 4OWUA 1OTPA 5C2LA 5BO3A 4LHMA 4ZOKA 1KHDA 1GXBA 5C7SA 4OWQA 4HKMA 4N93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4N8Q A;  1UOU A;  4ZOF A;  4OWO A;  4N5V A;  3R88 A;  4YI7 A;  4GKM A;  4GTN A;  1ZXY A;  2DSJ A;  4YYY A;  4YEK A;  4X5E A;  4X58 A;  4XR5 A;  5BNE A;  5BO2 A;  4M0R A;  3QR9 A;  2WK5 A;  3H5Q A;  4MUO A;  4X46 A;  2J0F A;  1BRW A;  1KGZ A;  4X5A A;  4X5B A;  5C1R A;  4ZOJ A;  4GA5 A;  4OWN A;  5EP8 A;  3QS8 A;  4EAF A;  2GVQ A;  1ZVW A;  3UU1 A;  5BYT A;  1AZY A;  1V8G A;  2TPT A;  4EAD A;  4X5C A;  4GA6 A;  4GA4 A;  4GIU A;  4ZTV A;  2BPQ A;  1VQU A;  4OWV A;  4OWM A;  1ZYK A;  4X59 A;  3TWP A;  1O17 A;  4X5D A;  4IJ1 A;  3GBR A;  3QSA A;  3QQS A;  2ELC A;  5EY3 A;  2WK6 A;  4OWS A;  3R6C A;  4OWU A;  1OTP A;  5C2L A;  5BO3 A;  4LHM A;  4ZOK A;  1KHD A;  1GXB A;  5C7S A;  4OWQ A;  4HKM A;  4N93 A; 
#chains in the Genus database with same CATH topology
 4N8Q A;  1UOU A;  4ZOF A;  4F3F C;  4OWO A;  4N5V A;  3R88 A;  4YI7 A;  4GKM A;  4GTN A;  1ZXY A;  2DSJ A;  4YYY A;  4YEK A;  4X5E A;  4X58 A;  4XR5 A;  5BNE A;  5BO2 A;  4M0R A;  3QR9 A;  2WK5 A;  3H5Q A;  4MUO A;  4X46 A;  2J0F A;  1BRW A;  1KGZ A;  1RRZ A;  4X5A A;  4X5B A;  5C1R A;  4ZOJ A;  4GA5 A;  4OWN A;  5EP8 A;  3QS8 A;  4EAF A;  2GVQ A;  1ZVW A;  3UU1 A;  5BYT A;  1AZY A;  1V8G A;  2TPT A;  4EAD A;  4X5C A;  4GA6 A;  4GA4 A;  4GIU A;  4ZTV A;  2BPQ A;  1VQU A;  4OWV A;  1RF8 B;  4OWM A;  1ZYK A;  4X59 A;  3TWP A;  1O17 A;  4X5D A;  4IJ1 A;  3GBR A;  3QSA A;  3QQS A;  2ELC A;  5EY3 A;  2WK6 A;  4OWS A;  3R6C A;  4OWU A;  1OTP A;  5C2L A;  5BO3 A;  4LHM A;  4ZOK A;  1KHD A;  1GXB A;  5C7S A;  4OWQ A;  4HKM A;  4N93 A; 
#chains in the Genus database with same CATH homology
 4N8Q A;  1UOU A;  4ZOF A;  4OWO A;  4N5V A;  3R88 A;  4YI7 A;  4GKM A;  4GTN A;  1ZXY A;  2DSJ A;  4YYY A;  4YEK A;  4X5E A;  4X58 A;  4XR5 A;  5BNE A;  5BO2 A;  4M0R A;  3QR9 A;  2WK5 A;  3H5Q A;  4MUO A;  4X46 A;  2J0F A;  1BRW A;  1KGZ A;  4X5A A;  4X5B A;  5C1R A;  4ZOJ A;  4GA5 A;  4OWN A;  5EP8 A;  3QS8 A;  4EAF A;  2GVQ A;  1ZVW A;  3UU1 A;  5BYT A;  1AZY A;  1V8G A;  2TPT A;  4EAD A;  4X5C A;  4GA6 A;  4GA4 A;  4GIU A;  4ZTV A;  2BPQ A;  1VQU A;  4OWV A;  4OWM A;  1ZYK A;  4X59 A;  3TWP A;  1O17 A;  4X5D A;  4IJ1 A;  3GBR A;  3QSA A;  3QQS A;  2ELC A;  5EY3 A;  2WK6 A;  4OWS A;  3R6C A;  4OWU A;  1OTP A;  5C2L A;  5BO3 A;  4LHM A;  4ZOK A;  1KHD A;  1GXB A;  5C7S A;  4OWQ A;  4HKM A;  4N93 A; 
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